LOCUS       NZ_KQ947989            22757 bp    DNA     linear   CON 21-APR-2024
DEFINITION  Streptomyces curacoi strain DSM 40107 PRJNA299217_s006, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ947989
VERSION     NZ_KQ947989.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces curacoi
  ORGANISM  Streptomyces curacoi
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 676431)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Draft genome sequence of Streptomyces curacoi DSM 40107, type strain
            for the species Streptomyces curacoi
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 676431)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-OCT-2015) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 13-OCT-2014
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 65.7x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001513975.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 02:05:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,531
            CDSs (total)                      :: 7,455
            Genes (coding)                    :: 7,251
            CDSs (with protein)               :: 7,251
            Genes (RNA)                       :: 76
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 204
            CDSs (without protein)            :: 204
            Pseudo Genes (ambiguous residues) :: 0 of 204
            Pseudo Genes (frameshifted)       :: 91 of 204
            Pseudo Genes (incomplete)         :: 154 of 204
            Pseudo Genes (internal stop)      :: 21 of 204
            Pseudo Genes (multiple problems)  :: 54 of 204
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:06:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 184375
            Orig. end                         :: 207132
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ947989.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22757
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="3"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22757
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22757
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12757](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12757
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            461..1045
                     /locus_tag="AQI70_RS21055"
                     /old_locus_tag="AQI70_21050"
     CDS             461..1045
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163: rhodanese domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133862.1"
                     /locus_tag="AQI70_RS21055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21050"
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="WP_062152375.1"
                     /transl_table=11
                     /translation="MTTHAHNTPRLDPAALRDLLQGGPGPRLLDVRTPGEFHTAHIPGS
                     CNVPLDTLREHRAELLRHLDQDAVLICRSGTRAAQAEQALAEAGLPGLRVLAGGVTAWE
                     AAGGPLTRGPERWALERQVRLVAGTLVLVTGVAGLALPGLHLIGTAVGAGLTVAALTNT
                     CAMGVLLSKLPYNRGPRTGLDTVVAALRGPS"
     gene            1042..1935
                     /locus_tag="AQI70_RS21060"
                     /old_locus_tag="AQI70_21055"
     CDS             1042..1935
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003851.1"
                     /locus_tag="AQI70_RS21060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21055"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_062152377.1"
                     /transl_table=11
                     /translation="MIALVVAASLLIGASLGVLGGGGSILTVPMLVYLAGTQTKEAIAT
                     SLFVVGVTSAAGVVTHARAGRIRWRTGLLFGLAGMAGAHAGGRLAESVPGTVLLIAFAL
                     MMIATAGAMIRGRRGERKQPHRELPVLHVLSEGVVVGFVTGLVGAGGGFLVVPALALLG
                     GLPMTVAVGTSLLVIAMNSFAGLAGHLTGARIDWGLAALVTATAVVGSQLGCRLTGRIP
                     QDALRRSFGWFVAVMGVFVLGGQLPPGLRHTLLTSPWTWAFGAAAGIAVSWSMLRRTER
                     STPGRADGPGPPRTLE"
     misc_feature    complement(1973..1989)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 20.97"
                     /tool="antismash"
     misc_feature    complement(1974..1989)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 21.53"
                     /tool="antismash"
     gene            2006..2293
                     /locus_tag="AQI70_RS21065"
                     /old_locus_tag="AQI70_21060"
     CDS             2006..2293
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003965298.1"
                     /locus_tag="AQI70_RS21065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21060"
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="WP_037891627.1"
                     /transl_table=11
                     /translation="MELELEGADLKAVLNRLRRAQGQISGVIRMIEEGRDCEDVVTQLA
                     AASRALDRAGFAIIATGLQRCVTDIESGRRNGEDTEAMRARLEKLFLSLA"
     gene            2580..3605
                     /locus_tag="AQI70_RS21070"
                     /old_locus_tag="AQI70_21065"
     CDS             2580..3605
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115266.1"
                     /locus_tag="AQI70_RS21070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21065"
                     /product="6-phosphofructokinase"
                     /protein_id="WP_062152379.1"
                     /transl_table=11
                     /translation="MKVAVLTGGGDCPGLNAVIRSAVRKGIQEYAFDFVGLRDGWRGAI
                     QGKVVPLDISSVRGILPRGGTILGSSRTNPLKHEDGVRRIQDTLATHEVDALIVIGGED
                     TLGAATELSRQGIRLVGVPKTIDNDVAGTDCTFGFDTAVGIATEAIDRLHTTAESHMRT
                     LVVEVMGRHSGWIALRAGVAGGANVILIPERPFDIDQVCAWVKSRFRINYAPIVVAAEG
                     AVPKEGQMILKDRSVDEYGHVRLSGIGEWLAREISERTGTDARTTVLGHIQRGGTPSSF
                     DRWLATRFGLHAVDAVKDGDFGKMVALRSTDIVRVPLADSTSTTKRVDPALYDEFEVFF
                     G"
     gene            complement(3636..4535)
                     /locus_tag="AQI70_RS21075"
                     /old_locus_tag="AQI70_21070"
     CDS             complement(3636..4535)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114680.1"
                     /locus_tag="AQI70_RS21075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21070"
                     /product="universal stress protein"
                     /protein_id="WP_062152381.1"
                     /transl_table=11
                     /translation="MSHPVLAGVDGSERSLVAAAWAAREAVLRGVPLRLLHVSPPLPGD
                     PGDVVPATALETLRQVGDHIVQRAIADLGARHPDLQVRGEQADAAPATALLAAARGAGL
                     LVVGARGSGGFDGLAVGSVALRSAAAAPCPVVLVPEPPAGGFGDRAWTTRGPAQVVVGF
                     DAHRPVGEVADFAFAAAQARGARLRAVQAWALPAEAVSPRTLFVTEEDRATWEDQEVLR
                     LSDAMRAWREKYPEVTVGTDVLLLHAAQALLHTSPGADLLVVGRRTDPRAAEGRLGPVT
                     HAVLHHARCPVAVVPHDG"
     gene            complement(4662..5516)
                     /locus_tag="AQI70_RS21080"
                     /old_locus_tag="AQI70_21075"
     CDS             complement(4662..5516)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662803.1"
                     /locus_tag="AQI70_RS21080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21075"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_062152383.1"
                     /transl_table=11
                     /translation="MDVELRQLRCLVAIVDEGSFTDAAIALGVSQAAVSRSLASLERAL
                     GVRLLRRTSREVTPTGTGLRVLAHARRVLGEVDDLVREATSGAARLRMGYAWAALGRHT
                     PAFQRRWTAAHPGTDLQLVRVNSATAGLAEGACELSVVRRPVDDRRFDSAIVGLERRLC
                     AVAADDPLARRRSVRLADLSARTLLVDRRTGTTTTDLWPPDSRPATEATHDVDDWLTVI
                     STGRCIGVTAEATAHQYPRPGVVYRPVRDAEPIAVRLAWWRDDPHPAAQAAIELLTALY
                     RGD"
     misc_feature    5548..5561
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.76"
                     /tool="antismash"
     gene            5585..6532
                     /locus_tag="AQI70_RS21085"
                     /old_locus_tag="AQI70_21080"
     CDS             5585..6532
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019356684.1"
                     /locus_tag="AQI70_RS21085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21080"
                     /product="EamA family transporter"
                     /protein_id="WP_244181761.1"
                     /transl_table=11
                     /translation="MRDRTAAAPTPAPAPTPAPAPGAPASVPGAPSPRAPKPAGAGLAG
                     VAAMIGSGLSNQTGAAIGSLAFPVLGPVGVVAVRQYVAALVLLTVGRPRLRTFTWGQWW
                     PVALLAVVFGTMNLSLYSAVERLGLGLAVTLEFLGPLTLALATSRRRTDACCAVIAAAG
                     VVVLMRPQPSADYPGMALGLLAAACWASYILLNRTVGRRIPGAQGAAAAAGLSALMFLP
                     IGLAVAVRHPPTAGALGCAIAAGVLSSAVPYLADLFTLRHVPARAFGLFMSVNPVLAAL
                     VGWIGLGQGLGPTEWASIGAIVAANALSILTSRS"
     gene            6940..7509
                     /locus_tag="AQI70_RS21090"
                     /old_locus_tag="AQI70_21085"
     CDS             6940..7509
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016641493.1"
                     /locus_tag="AQI70_RS21090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21085"
                     /product="DinB family protein"
                     /protein_id="WP_062152387.1"
                     /transl_table=11
                     /translation="MTRSERLADQLDRHWHKNLRPRLHGLADEEYFWEPVRGCWSIRPR
                     GTSAAPMSAGSGEWTMDSASPDPAPAPAPVTTIAWRLAHIIVSCLGYRVGWHFGGQDVD
                     SRTFAYAGTADEALKQLDEMYGRWNAGVRELSDADLENPPTVGPERFPMEGIVLHVNRE
                     LIHHGAEISLLRDLYRWQDGAVPRRI"
     gene            complement(7579..9012)
                     /locus_tag="AQI70_RS21095"
                     /old_locus_tag="AQI70_21090"
     CDS             complement(7579..9012)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003843.1"
                     /locus_tag="AQI70_RS21095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21090"
                     /product="MFS transporter"
                     /protein_id="WP_062152388.1"
                     /transl_table=11
                     /translation="MTHPETHPAPAPEHHHQRPDPRRWAALALVCLAQFMLILDVTVVN
                     VALPDMAADLDLGRATLTWVVTAYTLCFGGLMLLGGRLADALGARRTLLAGLSLFTAAS
                     LVAGLAAGAPALLGGRIAQGVAAALLSPAALSIVTTTFHGQERTKALGVWAAIGGSGAA
                     AGVLIGGALTDGPGWQWVFYVNVPVGLLVLAAVPAFVAARAPRPARLDVPGALLVTAGT
                     GALIYGLVAAGDSGWADPATLASLAGAVVAYALFALVERASRAPLMDLRMFTRRPVLAG
                     AFLMLVATALLIAHFFLGSAYLQHIRGFSPLKTGLVFLPVAVATGVGAHLGSRLVGTVG
                     SRTTAVAAMAVAAAGTVPLTRLSDTGSVYGGLLPGFVVASLGLGAAFVTATTTALAMVG
                     HREAGLASGVVNTFHEVGGSIGVAVVSTVAASGFERGTVGGFTDAFTVCAVAAGVSAAV
                     AVGLVPRGRPQLTGGPHVH"
     misc_feature    9080..9090
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     gene            9169..9825
                     /locus_tag="AQI70_RS21100"
                     /old_locus_tag="AQI70_21095"
     CDS             9169..9825
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010038917.1"
                     /locus_tag="AQI70_RS21100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21095"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_079051401.1"
                     /transl_table=11
                     /translation="MTMEGVKQPPSGPRAQLKRQAIVRAARELFLREGFGVGMDAIAAE
                     AGVSKVTVYNHFGSKEALFTAVITGALDEPLAADASAALEKLAEAEDLRAALLYAARTW
                     VRSVRANDDVTALRNLVAAESHRFPELGRAWRHHGPEGHHPAVANALRTLAEQGRLVVP
                     DLEAAIIQLYALLVFPHMVFASYGTHIDDDLTDRLITQGVDMFLSHYGPPDDVTS"
     gene            10001..12757
                     /gene="lanKC"
                     /locus_tag="AQI70_RS21105"
                     /old_locus_tag="AQI70_21100"
     CDS             10001..12757
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003841.1"
                     /locus_tag="AQI70_RS21105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21100"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_062152393.1"
                     /sec_met_domain="micKC (E-value: 2.2e-207, bitscore: 686.0,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1e-10, bitscore: 36.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.9e-06, bitscore:
                     22.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVYALADRHFYETPDRLSAGTDASPARGGTAPLYEPARRP
                     APDGWHAARIGDWLTLTPVDEDGRPRSGPTQGWKIHCSATRENAERIAAAVWDYCVPRL
                     IPFKFVPGPHLLHLRNAKYAARDSSGKFVTIYPSDEEQLQLVLCELGEILAGLEGPYIL
                     TDLRWNDGPLYVRYGAFARSFVVDERGTLVPAVRDGEGRLVPDRRQPAFQVPEWVSLPA
                     FLKPQLAARNTTTVGDLPYRIEKALHFSNGGGVYQGTDTRTGRKVVLKEGRPHAGLAAD
                     GADAIARLKREKDALERLAGLGVVPEVRDWFTLGDHRFLVMDFVEGRPLNSFFAERHPL
                     LAPDPEPGAVAAYTAWALRVHRAVEEAVEKVHERGIVFNDLHVFNIMVAPDEQSVFLLD
                     FEAAAPAEERGRQIVAHPGFLAPPDRTGADVDQYALACLRLALFLPVTSLLVVDRAKAA
                     HLAEVITSQFPDVPREFLDRAVAEITRDAGPGQGAPTRTEGGGAGRPGLPHSVAMSSFA
                     SLAEPGDWPYSRDSMVKAILASATPERDDRLFPGDVAQFSDGGGLGLAYGAAGVLYALA
                     ETGAERYDEGERWLLDHTDPVPLGTPLGLYDGLAGVAYVLDRLGHRQRALDLVEQILSE
                     KWQKLSSDLHGGLAGLGLVLGHLAGTTGETGLREQAAETTRLLVRRLAEPRPEAPRRRA
                     GLLRGASGPALFLLRQYEATGDPALLDAAGEALRQDLECCVVQADGALAVDEGWRTMPY
                     LGDGSVGVGMVIDDYLALRDPSASHALDPALGPTLDPAFETAFDPAFDPAFEQARAGIL
                     TAATYRFYAQAGLFQGRAGMILHLGRTGAPRARLAEQIAGLGWYAMPYQGQLAFPGHHM
                     MRLSMDLGTGTAGCLLALGATLAAEDSTAAQLPFLPPPRRRPTDAAP"
     misc_feature    10439..10441
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    10448..10450
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12818..12928
                     /locus_tag="AQI70_RS21110"
                     /old_locus_tag="AQI70_21105"
     CDS             12818..12928
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005483995.1"
                     /locus_tag="AQI70_RS21110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21105"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_004003840.1"
                     /transl_table=11
                     /translation="MALLDLQTMEADELTGAPSSLSVLSCVSAASITLCL"
     CDS_motif       12818..12877
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQTMEADELTGAPSS"
                     /locus_tag="AQI70_RS21110_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12878..12928
                     /prepeptide="core"
                     /locus_tag="AQI70_RS21110_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="9.10"
                     /molecular_weight="1489.8"
                     /monoisotopic_mass="1488.8"
                     /core_sequence="LSVLSCVSAASITLCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQTMEADELTGAPSS"
                     /leader_location="[12817:12877](+)"
                     /alternative_weights="1507.8"
                     /alternative_weights="1525.9"
                     /alternative_weights="1543.9"
     gene            13029..14771
                     /locus_tag="AQI70_RS21115"
                     /old_locus_tag="AQI70_21110"
     CDS             13029..14771
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003837.1"
                     /locus_tag="AQI70_RS21115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21110"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_062152395.1"
                     /transl_table=11
                     /translation="MTTPVPADCAPALLRAATRHSGARCAALALAALAATGANLLLPAA
                     LGRALDLLLAGAADATRWVLWCAALVLLLAVLDAFDTVLDGTTTARTTAWLRRRLTGHV
                     LAVGPRAVGRFGSGDLVARIVGIAAQAGTAPATLAALFAGLAGPVGAVVALGLISPWPA
                     AVLLGGAPVLALSLRVLARDSSGCAERYQQVQGRMASALSEAIEGHRTIAAAGTADRTV
                     ARILRPLPELSRAGHRMWRVQGRAAAQAAAVAPLLQVGVLAVAGFLLARQRLTVGELLA
                     ASRYAVLAAGIGVLVGQLSGLVQARTAARRLDEVLAEPAASYGVRHLPPGDGELELRGI
                     TVRRGGRTVLDGVDLVVPAGTTLAVVGRSGTGKSLLAAVAGRLTDPDEGEVRLDGVPLT
                     ELDRGALRRAIAYAFERPALLGESVEDTIAFGVPRPDRARVREAALAARADAFVRRLPD
                     GYATPVADAPLSGGEAQRLGLARAFARDSRVLILDDALSSLDTITEQHITEALLHHTAS
                     RTRLLVAHRASTASRADAVAWLDGGQVRAVGPHSELWQLAGYREVFGARPEGVARARSY
                     GGGG"
     gene            14771..16753
                     /locus_tag="AQI70_RS21120"
                     /old_locus_tag="AQI70_21115"
     CDS             14771..16753
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040507.1"
                     /locus_tag="AQI70_RS21120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21115"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_062152397.1"
                     /transl_table=11
                     /translation="MRGSGVHRRGLRFVRRRWRVVVRLVLWSALETAQAFLLGYALARA
                     LDDGFLAGRTDVGLGWLGAGAGAVLVGAYGTGRVYAGVAGLVEPLRDRLVRGVVERGVR
                     EADGGALSGFTQQVEIARDTFAGLVLVSRSFVFTAAGALIGLFSLAPPLLLVVAPPLAA
                     GVALFAAALRPLARRQERFLVADEALAAHLDTVCPGLRDITAGGAEERIATATDARVDA
                     EFRAARSLARWSVLRVASLAIGGQFPIVLLLATAPWLLDHGVTPGALVGALAYVTQSLL
                     PALQNLVHGLGASGSRLAVVLRRLAPPEEGGETKAAAPEVPGGTEKAASEAPGDTVKAA
                     SEELGGTKATGPEDRHGSKATAPSSATPDALTLTSLTFAYGPTSAPVIEDLTVRVAQGT
                     HLAVVGPSGIGKSTLTAVVAGLLDPRHGTVHLCGHPVPGDTARAHRVLIPQEAYVFRGS
                     LAENVGDLRPKPIPERELRAAADAVGLTALMERLGGPEAEVDPGALSAGERQLIALTRA
                     YLSYAPVVLLDEATCHLDAEAEERAERAFVERPGTTLVVVAHRVGSARRADRVLVMDGR
                     RVAYGHHDDLLERSPLYRELVLGTREPAGQQPLQPALPLRDTDGVDSVAGAGLAGDGRH
                     VVAHGPVGQVQAPGDLRHRRTLGGQ"
     gene            complement(<16679..17257)
                     /locus_tag="AQI70_RS40255"
                     /pseudo=""
     CDS             complement(<16679..17257)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="AQI70_RS40255"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGTREDGATGKREAGGGDVIRVLLVHDACLVRSVLAEWLRGEPEL
                     KVDDCSWRGAGKRVRSIRPDVCAADLDCADAYGIPPVADLCVRGAAGPAPRLLVLAQAS
                     RPGLLKRAAEAGALGFVDKEGAPERLVSAIREVAQGKRFVDDSLGFGFLKAAQMPLTRR
                     ELSVLSLAAEGASVAEIAGSLHLSHGTVRN"
     misc_feature    complement(16967..16969)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(17404..17419)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.87"
                     /tool="antismash"
     misc_feature    complement(17405..17419)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.42"
                     /tool="antismash"
     misc_feature    17418..17431
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.07"
                     /tool="antismash"
     misc_feature    17419..17432
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.84"
                     /tool="antismash"
     misc_feature    17420..17433
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.15"
                     /tool="antismash"
     misc_feature    complement(17434..17449)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.64"
                     /tool="antismash"
     gene            17549..18688
                     /locus_tag="AQI70_RS21125"
                     /old_locus_tag="AQI70_21120"
     CDS             17549..18688
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001586.1"
                     /locus_tag="AQI70_RS21125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21120"
                     /product="DUF475 domain-containing protein"
                     /protein_id="WP_062152399.1"
                     /transl_table=11
                     /translation="MLLRTFGWSFGVTAAGLALAAVLWGWEGFAVVAILSILEISLSFD
                     NAVVNAGVLKKMNAFWQKIFLTIGILVAVFGMRLVFPVVIVAVTAQLGPIEAVRLAIDD
                     ADRYQQLVTDAHPAIAAFGGMFLLMIFLDFIFEERDHTWLGPLERPLARLGRVDGLSVC
                     IALIALLVTATTIATQAAQHGGAHVDKSATVLLSGVAGLVTYLIVGGLSGHFENKLEEE
                     EEKEHEAEEEARKAGKQPSVVALAGKAAFFMFLYLEVLDASFSFDGVIGAFAITNDIFW
                     MALGLGIGAMYVRSLTVYLVRQGTLDDYVYLEHGAHYAIGALAVLLLVSIRWHINEVVT
                     GLIGVALIAASFWSSVRRNRALATAEQESGEKSEVMSGV"
     misc_feature    complement(18772..18783)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.31"
                     /tool="antismash"
     misc_feature    18777..18790
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.26"
                     /tool="antismash"
     misc_feature    18892..18906
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.88"
                     /tool="antismash"
     misc_feature    18894..18905
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.86"
                     /tool="antismash"
     gene            18969..21824
                     /locus_tag="AQI70_RS21130"
                     /old_locus_tag="AQI70_21125"
     CDS             18969..21824
                     /GO_function="GO:0016798 - hydrolase activity, acting on
                     glycosyl bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009331404.1"
                     /locus_tag="AQI70_RS21130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_21125"
                     /product="carbohydrate binding domain-containing protein"
                     /protein_id="WP_062152401.1"
                     /transl_table=11
                     /translation="MSEPLQRRSLLKLAVGTAATGWLWQGVGTAQAAADATPTTAPPAA
                     GPLDTLVFGNTASESAHGLTATLSDVVTGGLDQPARVLNVPESAGFWGGTLSATMACRP
                     RGATYVTIKLWGSESGAELGRLQLFAEGKQVGHYHLGAVDPLDIASEDPRTPERFFFHT
                     LPLPLDLTEGKESVSLEIRSMGRIAGYATSADSYYKAMEGPSRTVYRLYTHDEPYFALA
                     DGDVTGTLPPTTTRTSPGSEIVDTINARILARAASEASRTSPQLDLWYLDFLARAYGMP
                     ATAAHANIAVPPQIARSLDGIYWRYRADSAVMTNSSQQWMGLGRSGLVMLALADVLAPL
                     LDEPVLGSPYGLTNPGFEFGTTGWRSSTWSGSGTASRDTTVYRTGHASAKVTVPTAGTV
                     GYTTSARIPVDQGTYTYGGWIRTAGVGTRSAYLDILFHDANGAVVGTDNKVHASAGTHD
                     WEHVTASLTTPGTATHVTLSVRLSGAGTAWFDDLTMVEPEGSAYAPVVRRDAWARMLLD
                     SREYWRQNFPQYTNQAIICAIGLYLADRGLTYLGSADAWGEKKARDYIYQSVGLVPWLG
                     PEKPDGTPTRPLGGSYHQVTKKGISKELGYAGSYGELQEWLSLVYDAVTGIGGVEDGTL
                     RDHLVKMAKARMVFRHPSLDRDGHRAMRLETVVGWRDNEYPGKVAYDQDAKWDGHALKM
                     AAQIKDPDLVSYARQSLADGQAFQSLADSHAATVSARTNLNLLSTADDYAYISKATGSG
                     AKLPMTPGAPDFVFSDEENGLVAIKHGDEILFASLYWRARWGVNRLARVHHLTAEGTER
                     SATVWQEVKYLADGRTFTEPDWVNWEFTVSDLDIPDGGFTPPGNALHQAFAGQVLPLAK
                     APDDVPERAAGVESPYAGRASFYRCEYGPYLIAMNTTDDRDHTFTTRGFGASTNLVTGA
                     KVSGNTEVRVKPGTTVVLRKR"
     misc_feature    complement(18970..18984)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.88"
                     /tool="antismash"
     misc_feature    21925..21936
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.78"
                     /tool="antismash"
     misc_feature    complement(21926..21939)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.59"
                     /tool="antismash"
     misc_feature    21926..21939
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.34"
                     /tool="antismash"
     misc_feature    22411..22425
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.44"
                     /tool="antismash"
ORIGIN
        1 cgcctttccc gccctcgcgg acgagatacg gcaggccggc cgtgtgacgg cggacgagtt
       61 gcgtcggctg ctggccggtg acgacgcgcc gctggtgctg gacgtgcgca accccgccga
      121 gcgcgaagag ggcttcatcg agagctcgtt gcacatcccg ctggccgaac tggcccgccg
      181 tacgcacgag atcccggccg gccggccgct ggtggtgcac tgcgcgggcg gccaccgctc
      241 ctccatcgcc gccagtctgc tgcggcaccg gggccgcacc gacgtctccg acctgctcgg
      301 cggcttcggc gcctggctca cccacccctc ccccacgctc ggcggcgccg gcgcggtggg
      361 agccccgtcg gccgacgcct gacgcaccgc actccgggcg gcggccccga ggcaccggcc
      421 gccgcccggc ccggccactt cgacgacagc gaggaacccc atgaccaccc atgcccacaa
      481 caccccacgg ctcgaccccg ccgcgctgcg cgacctgctc cagggcgggc ccggcccacg
      541 cctgctggac gtgcgcacgc ccggcgagtt ccacaccgcc cacatccccg gctcctgcaa
      601 cgtccccctc gacaccctgc gcgaacaccg cgccgaactg ctgcggcacc tcgaccagga
      661 cgccgtcctc atctgccgct ccggcacccg cgccgcccag gccgaacagg ccctcgccga
      721 agccgggctg cccggcctgc gcgttctcgc cggcggggtg acggcatggg aggccgccgg
      781 aggtccgctc acgcgcggcc cggaacgctg ggccctggag cgccaggtcc gccttgtcgc
      841 cggcaccctg gtgctggtga cgggcgtcgc cggtctcgcc ctgcccggcc tgcacctgat
      901 cggcacggcc gtcggcgccg ggctgaccgt cgccgcgctc acgaacacct gcgcgatggg
      961 cgtactgctg tcgaagctgc cctacaaccg cggcccgcgc accggcctcg acaccgtcgt
     1021 cgccgcgctg cggggcccgt cgtgatcgcc ctggtcgtcg cggcgtcgct gctcatcggg
     1081 gccagtctcg gcgtgctggg gggcggcggc tccatcctga ccgtgcccat gctggtctac
     1141 ctggccggca cacagaccaa ggaggccatc gccacctcac tgttcgtcgt cggcgtcacc
     1201 agcgccgccg gggtggtcac gcacgcccgc gcggggcgca tccgctggcg tacgggactg
     1261 ctgttcggtc tggccggaat ggccggcgcc catgcgggcg gccggctggc cgagtccgtc
     1321 cccggcaccg tcctgctgat cgcgttcgcc ctcatgatga tcgccaccgc cggcgcgatg
     1381 atccgaggcc gccgaggcga gcggaagcag ccgcaccgcg aactccccgt cctccacgtc
     1441 ctgtcggagg gcgtcgtggt gggtttcgtg accggcctgg tcggcgccgg cggaggcttc
     1501 ctcgtcgtgc ccgccctcgc gctgctcggc gggttgccga tgaccgtcgc ggtcggcacc
     1561 tcactgctgg tcatcgcgat gaactcgttc gccgggctgg ccggtcacct caccggggcg
     1621 cgcatcgact ggggcctcgc ggccctcgtc accgcgaccg ccgtggtcgg cagccagctc
     1681 ggctgccgcc tcacggggcg catcccgcag gacgcgctgc gcaggtcctt cggctggttc
     1741 gtcgccgtca tgggcgtctt cgtcctcggc ggccagctgc cccccggcct gcgccacaca
     1801 ctgctcacca gcccctggac ctgggcgttc ggggccgcgg cggggatcgc ggtcagctgg
     1861 tccatgctgc gcaggaccga acggtcgacg ccgggccgcg ccgacggccc cggccccccg
     1921 cgtaccctcg aatgatcatc aatggtcgac gtcgccccga accgggacgt acagtacccc
     1981 taggggtatg tcctgaggag tgatcgtgga actggagctc gagggtgcgg acctgaaggc
     2041 cgtactgaac cggctgcgcc gggcgcaggg tcagatctcc ggtgtgatcc ggatgatcga
     2101 ggaggggcgc gactgcgagg acgtagtcac ccagctcgcc gccgcctccc gtgcgctcga
     2161 ccgggccggt ttcgcgatca tcgcgaccgg cttgcagcgg tgcgtgacgg acatcgagtc
     2221 cggccgcagg aacggcgagg acacggaagc catgcgtgcc cgtctggaga agctgttcct
     2281 gtccctggca taggcgtccc tggcactggc agccctggca tcggcgtccc tggcattggc
     2341 gtccctggct aggacccgcc ggggcgaggc tccgccgaat cagccgaagc tcccccctgt
     2401 ggcaggcccc ggggtaggtc gccgacaggg ccgcctgcgc tcatgatgga aggagagtcc
     2461 agggctcttc gagttcagcg cgaggacgtc ctcaagcggc tgaaccggct ccttcagtcc
     2521 gcggcgccgt cttgatcggg caggacatgc cgccactctc gcagaagagg gaggaagcca
     2581 tgaaggtcgc agtgctgacc ggcggcggtg actgtcccgg cctcaacgcc gtgatccgca
     2641 gtgccgtccg caagggcatc caggagtacg ccttcgactt cgtcggcctg cgcgacggct
     2701 ggcgcggcgc gatccagggg aaggtcgtac cgctggacat ctccagtgtg cggggcatcc
     2761 tgccccgcgg cggaaccatc ctcggctcct cccgtaccaa cccgctcaaa cacgaggacg
     2821 gcgtgcggcg catccaggac accctcgcca cgcacgaggt ggacgcgctc atcgtgatcg
     2881 gcggcgagga cacgctcggt gcggccaccg aactgagccg acagggcatc cgcctggtcg
     2941 gcgtgcccaa gaccatcgac aacgacgtgg ccggcaccga ctgcaccttc ggcttcgaca
     3001 cggccgtggg catcgcgacg gaggccatcg accgtctcca caccacggcc gagtcgcaca
     3061 tgcgcaccct ggtggtggag gtgatgggcc gacactccgg ctggatcgcc ctgcgcgccg
     3121 gcgtcgcggg cggcgccaac gtgatcctca tccctgagcg gccgttcgac atcgaccagg
     3181 tctgcgcgtg ggtgaagagc cgattcagga tcaactacgc gccgatcgtc gtcgccgccg
     3241 agggagccgt gcccaaggaa gggcagatga tcctcaagga ccggtcggtg gacgagtacg
     3301 gccatgtccg gctgtccggc atcggcgagt ggctggctcg ggagatctcg gaacgcaccg
     3361 gcacggacgc ccgcacgacg gtgctcggtc atatccagcg cggcggcacg ccgagctcct
     3421 tcgacaggtg gctggccacg cgcttcgggc tgcacgccgt cgacgccgtc aaggacggtg
     3481 acttcggcaa gatggtggcc ctgcggagca ccgacatcgt ccgtgtgccc ctcgccgact
     3541 cgacgagcac gaccaagcgg gtcgatcccg cgctgtacga cgagttcgag gtgttcttcg
     3601 gctgaccctc gccgcggtca gccgtcatgc cgcggtcagc cgtcatgcgg tacgaccgcc
     3661 accgggcagc gggcgtggtg cagcacggcg tgggtcaccg gtcccaaccg gccctcggcc
     3721 gcccgggggt cggtgcggcg gcccacgacc agcaggtccg ctcccgggga cgtgtgcagc
     3781 agtgcctgcg cggcgtggag caggaggaca tcggtgccga ccgtcacctc cgggtacttc
     3841 tcccgccacg cccgcatcgc gtcggagagc cgcaggacct cctggtcctc ccaggtggcg
     3901 cggtcctcct cggtcacgaa cagcgtccgg ggagacacgg cctcggcggg cagagcccag
     3961 gcctgaaccg cccgcagacg cgccccgcgc gcctgggcgg ccgcgaacgc gaagtccgcc
     4021 acctcgccga ccggacggtg tgcgtcgaaa cccaccacga cctgggccgg accgcgggtc
     4081 gtccacgccc ggtccccgaa ccccccggcc ggcggttcgg gcacgaggac gacggggcag
     4141 ggggctgccg ccgccgagcg aagggccacc gaaccgaccg cgagcccgtc gaagccgccc
     4201 gagcctcgcg caccgaccac gaggagcccg gcgccgcgcg ccgcggcgag gagcgcggtg
     4261 gccggggccg cgtcggcctg ctcgccccgc acctggaggt ccgggtggcg ggcgccgagg
     4321 tcggcgatcg cacgctggac gatgtggtca ccgacctggc gcagcgtctc cagggccgta
     4381 gccgggacga cgtcacccgg gtcgcccgga agcggcgggg agacatgcag cagccgcagc
     4441 ggaacgccac gcagcaccgc ttcccgcgcg gcccaggcgg cggcgaccag gctccgctcg
     4501 gacccgtcga cacccgccag caccgggtga ctcatcgcgc cctccttcgc cgaccgtgca
     4561 cttccgcagg agcgccacgc gtgcctttcg ccgcttcttc cactgttcca cggtgggcgc
     4621 actgttccac ggtgggcgcc ggaccggccg aaccgcggag gtcagtcgcc ccggtacagg
     4681 gcggtgagca gttcgatcgc cgcctgggcg gcgggatgcg ggtcgtcgcg ccaccaggcc
     4741 agccgtacgg cgatgggttc cgcgtcccgc accggccggt agaccacgcc gggccgcggg
     4801 tactggtggg cggtggcctc ggcggtgacc ccgatgcagc ggcccgtgga gatcacggtc
     4861 agccagtcgt cgacgtcgtg cgtcgcctcg gtcgccgggc gggagtccgg cggccacaga
     4921 tcggtggtcg tggtgccggt acggcggtcg acgagcaggg tacgggcgct gaggtcggcc
     4981 agccggaccg agcggcgccg ggccagcgga tcgtccgcgg ccacggcgca cagccgccgc
     5041 tccagtccga cgatggcgga gtcgaagcgg cggtcgtcca ccggccggcg tacgacggac
     5101 agctcgcagg ctccctccgc gaggcccgcg gtcgcggagt tgacgcggac gagttgcagg
     5161 tcggtcccgg gatgggcggc ggtccagcgg cgctggaagg ccggggtgtg ccggccgagc
     5221 gccgcccagg cgtagcccat ccgcagccgg gccgctccgg acgtagcctc ccggaccagg
     5281 tcgtcgacct cgccgagcac ccgacgggcg tgcgccagga cgcgcagccc ggtgcccgtc
     5341 ggggtcacct cgcgggaggt ccggcgcaac agccgtacgc ccagggcgcg ttcgagcgag
     5401 gcgagcgagc gggacacggc ggcctgggag acgccgaggg cgatcgcggc gtcggtgaaa
     5461 ctgccctcgt cgacgatcgc gaccagacag cgcaactgcc tcaactccac atccatgagc
     5521 caagcgtata gatggcccgt cggctgcatt ttgcgcaaag atcgaggggc cgcacgatca
     5581 gcgcatgcgc gaccgaaccg cagccgcacc cacacccgca cccgcaccga cccctgcccc
     5641 tgcccctggt gcccccgcct ccgtacccgg agccccgtcg ccgcgggccc cgaagccggc
     5701 cggcgcgggc ctcgccggtg tggccgcgat gatcggcagt ggcctgtcca accagaccgg
     5761 tgccgcgatc ggctccctcg ccttccccgt cctcggcccg gtcggggtcg tcgcggtacg
     5821 ccagtacgtc gccgccctcg tcctgctgac cgtgggtcgg ccccggctgc ggacgttcac
     5881 gtggggtcag tggtggccgg tggccttgct ggccgtggtg ttcggcacca tgaacctgtc
     5941 gctgtacagc gccgtcgagc ggctggggct gggcctggcg gtgaccctgg agttcctggg
     6001 gccgctcacc ctcgccctgg ccacctcgcg ccggcgcacg gacgcgtgct gcgcggtgat
     6061 cgccgcggcg ggcgtcgtcg tcctgatgcg gccccagccc tccgccgact acccgggcat
     6121 ggccctgggc ctcctggccg ccgcctgctg ggcgtcgtac atcctgctca accgcacggt
     6181 cggccgacgt atccccggag cccagggcgc ggcggccgcc gccgggctgt ccgccctgat
     6241 gtttctgccg atcggcctcg ccgtggctgt ccggcaccct ccgacggcgg gcgcgctcgg
     6301 ctgtgcgatc gccgccggcg tcctctcctc ggccgtccct tacctggcgg acctgttcac
     6361 cctgcgccat gtaccggccc gggccttcgg cctgttcatg agcgtcaacc cggtcctggc
     6421 cgccctggtc ggctggatcg gcctcggcca ggggctcggc ccgacggagt gggcgagcat
     6481 cggggccatc gtcgccgcca acgcgctgag cattctcacg tcacggagct gatggcgggt
     6541 catacggcgg gtacggcacc gcggaagtca cgcccgcgct gccgtactcc gcgagccggg
     6601 ccggcccgcc ccgttcagtg agtcttcgcc atcttcgaac atgaaggtcg caggctctgg
     6661 cgtggcgctc gctcgggata ctcatgctga tctcgggcgg gggtctgtgg tcttgatcat
     6721 ccgtcatgtc atcgctctca aggccgtcac atttgggtca tagaacccaa cccggccagc
     6781 cgggttgtca atgtcaaaca gccgctcgcg gcggcgcggg ccgaagggca catcgacccc
     6841 cagcgtcatc tcccggtgcg gtacgctctc gcggcccacg gccggcgacg gcgtccgcga
     6901 gggtcgcagc caggtctccg tcgtatgtag tgtgcggaaa tgacaagaag cgagcggctc
     6961 gcggaccagt tggaccggca ctggcacaag aacctgcggc cgcggctgca cggtcttgcc
     7021 gatgaggagt acttctggga gccggtgcgc ggctgctgga gcatccgccc acgtggcacg
     7081 tcggccgcac cgatgtcggc aggttcgggg gaatggacga tggactccgc gtctcctgac
     7141 ccggcgccgg cgccggcgcc ggtgaccacg attgcctggc ggctggcgca catcatcgtc
     7201 tcctgcctgg gctatcgggt cggatggcac ttcggcggcc aggacgtcga ctcccggaca
     7261 ttcgcctacg cggggaccgc tgacgaggcg ctgaaacagc tcgatgagat gtacgggaga
     7321 tggaacgcgg gggtccgcga actctcggac gccgacctgg agaatccgcc cacggtgggt
     7381 cccgagcggt ttcccatgga gggcatcgtc ctgcacgtca acagggagct gatccatcac
     7441 ggcgccgaga tttccctgct gcgcgacctc taccgatggc aggacggagc cgtaccgcgc
     7501 cgaatatgac tttccggtaa ccggcgatcg agcttcggaa actttcatgg actccgtgac
     7561 gctccgtggc tgcgagcttc agtgcacgtg gggtccgccg gtcagttgcg gcctgccgcg
     7621 cgggaccagc ccgacggcca cggccgcgct gaccccggcc gccaccgcgc acacggtgaa
     7681 ggcgtcggtg aagccgccga ccgtgccgcg ctcgaagccg gaggcggcga cggtggagac
     7741 gaccgccacg ccgatcgaac cgcccacctc gtggaaggtg ttgacgacac cggacgccag
     7801 ccccgcctcc cggtgcccga ccatggcgag cgccgtggtg gtggcggtga cgaaggccgc
     7861 gccgaggccg agtgaggcga ccacgaagcc cggcaggagg ccgccgtaca cactgccggt
     7921 gtcggacagc cgggtcagcg gcacggttcc ggcggcggcc accgccatcg cggcgacggc
     7981 cgtcgtacgg ctcccgacgg tgccgaccag ccgggagccc aggtgggcac cgacgccggt
     8041 ggcgacggcc acgggcagga acaccaaccc ggtcttcaag gggctgaagc cacggatgtg
     8101 ctggaggtag gccgagccga ggaagaagtg ggcgatcagc agcgcggtcg ccaccagcat
     8161 caggaacgct ccggcgagca ccggacgccg ggtgaacatg cgcaggtcca tcagcggggc
     8221 ccggctcgcc cgctcgacca gggcgaacag tgcgtaggcc acgaccgcgc cggccagcga
     8281 cgccagcgtg gcgggatccg cccacccgga gtcgcccgcc gccacgagcc cgtagatcag
     8341 cgcgccggtg cccgcggtca ccagcagcgc accgggcacg tcgagccggg cgggccgagg
     8401 cgcgcgggcc gccacgaacg ccgggacggc ggcgaggacg aggagaccga ccggcacgtt
     8461 gacgtagaag acccactgcc agccgggccc gtcggtgagc gcgccgccga tcagcacccc
     8521 ggccgcggcg ccggacccgc cgatcgccgc ccacacgccg agtgccttgg tgcgctcctg
     8581 gccgtggaag gtggtcgtga cgatcgacag cgcggcgggc gaaagcaggg cggcggcgac
     8641 gccctgggcg atacgtccgc ccagcagggc cggggcgccg gcggccaggc cggcgaccag
     8701 cgacgcggcg gtgaacaggg acagtccggc gagcagggtg cggcgcgctc cgagggcgtc
     8761 ggcgaggcgc ccgccgagga gcatgaggcc gccgaagcag agggtgtacg cggtgacgac
     8821 ccaggtcagg gtcgcgcggc cgaggtcgag gtcggcggcc atgtcgggca gggcgacgtt
     8881 caccacggtg acatcgagga tcagcatgaa ctgggcgagg cagaccagcg ccagcgccgc
     8941 ccagcggcgg gggtcggggc gctggtgatg gtgctccggc gcaggggccg ggtgggtttc
     9001 cgggtgggtc acggcgagtc cttaggggtg aggggcgggg cgggagtccg ctgggcggga
     9061 cgagtggatg agggctgggt gcactgtcac ctggccacgc atttgaactg cactgtgcag
     9121 ttcatctgaa ctcaactgta cagttcaggt ccctgctagg ctctccccgt gaccatggaa
     9181 ggtgtgaagc agcccccgag cggcccccgt gcccagctca agcggcaggc catcgtccgg
     9241 gcggcccgcg agctgtttct gcgggagggc ttcggcgtcg gcatggacgc catcgccgcc
     9301 gaggccggcg tgtccaaagt gaccgtctac aaccacttcg gcagcaagga agccctcttc
     9361 accgcggtca tcaccggagc cctggacgaa cccctcgccg cggacgcgtc agccgcgctg
     9421 gagaagctgg cggaggccga ggacctgcgg gcggccctcc tctacgcggc ccgcacctgg
     9481 gtccgctcgg tacgcgccaa cgacgacgtc accgccctgc gcaacctcgt ggccgccgag
     9541 tcccaccggt tcccggagct gggccgggcc tggcggcacc acggaccgga gggccaccac
     9601 cccgccgtgg cgaacgcgct gcgcaccctc gcggagcagg gccggctggt cgtccccgac
     9661 ctggaggcgg ccatcatcca gctctacgcc ctgctggtct tcccccacat ggtcttcgcc
     9721 tcctacggca cccacatcga cgacgacctc accgaccggc tcatcaccca gggcgtcgac
     9781 atgttcctga gccactacgg ccccccggac gacgtgacct cctaacgccc cgacgagcga
     9841 gtggaccgcg cgagtcgaaa gcagccgaac atctcttaac gcatgcgtac cgcacggtga
     9901 cggcgtgaca ggcgtgacgg attactggtg acaggcggga ctgtccggtg cccccgagtg
     9961 gctggaaggc tcggcgtcac gccgtcgagg gggttcgcgc atggacaagc ggtacgaggt
    10021 gtacgcgctc gccgacagac acttctacga gacaccggac cggctgtcgg ccggtacgga
    10081 cgcctccccg gcccgaggcg ggaccgctcc cctgtacgag ccggcccgcc gcccggcacc
    10141 cgacggctgg cacgcggcga ggatcggcga ctggctcacg ctgaccccgg tcgacgagga
    10201 cggccggccg cgctccggac cgacccaggg ctggaagatc cactgttcgg ccacccggga
    10261 gaacgccgag cggatcgcgg cggccgtgtg ggactactgc gtgccccggc tcatcccgtt
    10321 caagttcgtg ccgggcccgc acctgctgca cctgcgcaac gccaagtacg cggcgcgcga
    10381 cagcagcggc aagttcgtga cgatctaccc gtccgacgag gagcaacttc agctcgtctt
    10441 atgcgagtta ggggaaatcc tggccggcct ggaggggccg tacatcctca ccgacctgcg
    10501 ctggaacgac gggccgctgt atgtccggta cggcgccttc gcgcgctcct tcgtcgtcga
    10561 cgagcgcggc acgctcgtcc cggcggtccg cgacggcgag ggcaggctgg tgccggaccg
    10621 gcggcagccg gccttccagg tccccgagtg ggtgagtctg cccgcgttcc tcaagccgca
    10681 gctcgcggcg cggaacacga cgacggtcgg cgacctgccg taccgcatcg agaaggcgct
    10741 gcacttctcc aacggcggcg gggtctacca gggcaccgac acccgcaccg gccgcaaggt
    10801 cgtcctcaag gaggggcgtc cgcacgcggg gctcgccgcg gacggggccg acgccatcgc
    10861 ccggctgaag cgggagaagg acgccctgga acggctggcg ggcctgggtg tcgtgcccga
    10921 ggtgcgggac tggttcacgc tcggcgacca ccgcttcctc gtcatggact tcgtcgaggg
    10981 ccgcccgctg aactcgttct tcgccgagcg gcacccgctg ctcgcacccg atcccgagcc
    11041 gggcgcggtc gccgcgtaca cggcgtgggc gctgcgcgtg caccgggccg tcgaggaggc
    11101 ggtcgagaag gtgcacgagc gcgggatcgt cttcaacgac ctgcatgtct tcaacatcat
    11161 ggtcgcgccc gacgaacaat ccgtgttcct gctggacttc gaggcggcgg caccggccga
    11221 ggagcggggc cggcagatcg tcgcccatcc cggcttcctc gcgccaccgg accgtacggg
    11281 cgccgacgtc gaccagtacg cgctcgcctg tctgcggctg gcgttgttcc tgccggtgac
    11341 ctcgctgctg gtggtggacc gcgccaaggc ggcacatctg gccgaggtga tcacgagtca
    11401 gttcccggat gtgccgcggg agttcctcga ccgggcggtg gcggagatca cccgcgacgc
    11461 cggtccgggc cagggcgcgc cgacccgcac cgagggcggc ggggcgggcc ggcccgggct
    11521 tcctcactcc gtggcgatgt cgtcgttcgc ctcgctcgcg gagccgggcg actggccgta
    11581 cagccgtgac tccatggtca aggcgatcct cgcctcggcc acgcccgaac gcgacgaccg
    11641 cctgttccct ggcgacgtgg cgcagttctc ggacggcggc gggctggggc tcgcgtacgg
    11701 cgccgcgggc gtcctctacg cgctcgccga gaccggggcc gagcggtacg acgagggcga
    11761 gcgctggctg ctcgaccaca ccgacccggt accgctcgga accccgctgg gcctctacga
    11821 cggactcgcg ggcgtcgcgt acgtcctgga ccggctcggg caccggcagc gggcgctgga
    11881 cctggtcgag cagatcctga gcgagaagtg gcagaagctg tcctccgacc tgcacggcgg
    11941 actggccggg ctcgggctcg tcctgggaca cctggcgggc acgaccggcg agaccgggct
    12001 gcgcgaacag gcggccgaga ccacgcgcct gctcgtccgg cggctcgccg agccccggcc
    12061 cgaggcgccc cgccgccgcg ccggacttct ccggggagcg agcgggcccg cgctcttcct
    12121 cctgcggcag tacgaggcga ccggcgaccc cgccctgctg gacgcggcgg gagaggcgct
    12181 gcggcaggac ctggagtgct gtgtcgtgca ggcggacggc gctctcgcgg tcgacgaggg
    12241 gtggcgcacc atgccgtacc tcggggacgg cagcgtgggc gtcgggatgg tgatcgacga
    12301 ctacctggcg ctccgggatc ccagcgcgtc ccacgccctc gatcccgcgc tcggccctac
    12361 tctcgatccc gccttcgaaa ccgccttcga tcccgccttc gatcccgcct tcgaacaggc
    12421 ccgcgccggc atcctcaccg ccgccaccta ccgcttctac gcgcaggccg ggctcttcca
    12481 gggccgcgcc ggaatgatcc tgcacctcgg ccgcacgggt gcgccccggg cgcggctcgc
    12541 cgaacagatc gcgggactcg gctggtacgc catgccgtac cagggccaac tggccttccc
    12601 cggccaccac atgatgcggc tctccatgga cctcggtacc ggaacggccg gttgcctgct
    12661 ggcgctcggc gcgaccctcg ccgccgaaga ctccaccgcg gcccagctgc cgttcctgcc
    12721 gccgccccga cggcggccca cagacgcggc tccgtgacct gacggagtcg tgacgcaaca
    12781 ctcccgtccc cattgaagga tcaagaaggg aatcgacatg gcactgctcg acctgcagac
    12841 gatggaagcc gacgagctga cgggcgcccc cagctccctc agcgtgctgt cctgcgtcag
    12901 tgcggcaagc atcaccctct gcctctgagc gacttcgtcg tatcgaggct cacggccccg
    12961 gacggtccct cccgtaccgg gaggggccgc tcggggcctt cccgcatgcg tgaccgatgc
    13021 gaggtggcat gaccacgcct gttccggcgg actgcgcccc cgcgctgctg cgcgcggcca
    13081 cccgccacag cggcgcccgc tgtgcggccc tggccctggc cgccctggcc gccacgggcg
    13141 cgaacctcct gctgcccgca gcactcgggc gcgccctcga cctgctgctg gccggcgccg
    13201 cggacgcgac acgctgggtg ctgtggtgtg ccgctctcgt gctgctgctc gccgtcctgg
    13261 acgcgttcga caccgtgctc gacggcacca cgaccgcccg gaccacggcg tggctgcgca
    13321 ggcggctgac gggccatgtg ctggcggtgg ggccgcgcgc ggtgggccgc ttcggttccg
    13381 gggatctggt ggcgcggatc gtcggcatcg cggcgcaggc cgggacggcg cccgccaccc
    13441 tggccgccct gttcgcgggg ctggccggtc cggtcggcgc ggtggtggcg ctcgggctga
    13501 tcagcccctg gccggccgcg gtgctcctcg gcggggcgcc ggtgctggcc ctgtcactgc
    13561 gggtcctcgc ccgggactcc tcggggtgcg cggagcgcta ccagcaggtc caggggcgga
    13621 tggcgagtgc cctgtccgag gcgatcgaag gccaccgtac gatcgccgcc gccgggacgg
    13681 cggaccggac ggtggcgcgc atcctgcgtc cgctgcccga actctcccgc gcgggtcacc
    13741 gcatgtggcg ggtccagggc cgcgccgccg cacaggcggc cgccgtggca ccgctgctcc
    13801 aggtgggagt gctggcggtg gcgggcttcc tgctcgcccg acagcgcctg accgtgggcg
    13861 agttgctcgc cgcctcccgg tacgccgtgc tggccgcggg catcggcgta ctggtcgggc
    13921 agctgtccgg cctggtgcag gcgcggacgg cggcccgacg tctcgacgag gtcctggccg
    13981 aacccgccgc ctcctacggc gtacgccatc tcccgcccgg ggatggagag ttggagctgc
    14041 gcggcatcac cgtccggcgc ggcgggcgca cggtactgga cggcgtcgac ctcgtcgttc
    14101 cggcggggac cacactggcc gtggtcggcc gctcagggac gggcaagtcg ctgctcgccg
    14161 ccgtcgccgg ccggctgacg gacccggacg agggtgaagt acggctcgac ggagtccccc
    14221 tgaccgagct ggaccgcggc gcactgcgcc gggcgatcgc ctacgccttc gaacgccccg
    14281 cgctgctcgg cgagtcggtc gaggacacga tcgccttcgg tgtcccccgc cccgaccggg
    14341 cccgcgtccg tgaggccgct ctggccgccc gcgccgacgc gttcgtccgc cgtctccccg
    14401 acgggtacgc cacccccgtc gccgatgccc ccctgtcggg cggcgaggcc caacggctcg
    14461 gcctcgcccg ggcgttcgcc cgcgacagcc gggtcctcat tctcgacgac gccctgtcca
    14521 gcctcgacac gatcaccgag cagcacatca ccgaggccct cctccaccac accgcgagcc
    14581 gcacccgtct gctggtcgcc caccgcgcct cgacggcgtc ccgcgcggac gccgtggcgt
    14641 ggctggacgg aggccaggtg cgggcggtgg gcccgcactc cgagctgtgg caactggcgg
    14701 gctaccgcga ggtgttcggg gcgcgccccg agggcgttgc ccgagcacgg tcgtacggcg
    14761 gagggggctg atgcgcgggt ccggtgtgca ccgacgaggg ctgcggttcg tgcggcggcg
    14821 gtggcgggtc gtcgtacgcc tcgtcctgtg gtcggcgctg gagaccgcgc aggcctttct
    14881 cctggggtac gccctggccc gcgccctcga cgacgggttc ctggccggcc gcaccgacgt
    14941 cgggctcggc tggctcgggg cgggggcggg cgccgtgctc gtgggggcgt acgggacggg
    15001 ccgggtctac gcgggtgtcg ccgggctggt cgagccgttg cgggaccggc tggtgcgcgg
    15061 ggtggtcgag cggggggtgc gggaggcgga cggcggggcg ctgtcggggt tcacccagca
    15121 ggtggagatc gcccgggaca ccttcgcggg gctggtgttg gtctcccgct cgttcgtgtt
    15181 caccgccgcc ggggcgctga tcggactgtt ctcgctcgcg ccgccgctgc tgctcgtggt
    15241 cgctccgccg ctcgccgccg gggtggctct gttcgcggcg gccctgcggc cactggcccg
    15301 caggcaggag cggttcctcg tcgcggacga ggccctcgcc gcccacctgg acaccgtctg
    15361 cccggggttg cgggacatca cggcgggcgg cgcggaggag cggatcgcca cggcgacgga
    15421 cgcccgcgtg gatgccgagt tccgagcggc gcgctcgctg gcccgttgga gcgtcctgcg
    15481 ggtggcctct ctcgcgatcg gcggacagtt cccgatcgtg ctgctcctcg ccaccgcgcc
    15541 ctggctcctg gaccacgggg tcactccggg cgccctcgtc ggtgccctcg cctacgtcac
    15601 ccagtccctg ctgcccgcgc tgcagaacct ggtgcacggc ctgggcgcga gcggctcgcg
    15661 actcgcagtc gtactgcggc gactggcacc gcccgaggag gggggcgaga cgaaggcggc
    15721 agcaccggag gtgccgggcg gcacggagaa agcagcatcc gaggcgcccg gcgacacggt
    15781 gaaggcagca tccgaggagc tgggcggcac aaaggcgaca ggacccgagg atcggcacgg
    15841 ctcaaaagcg acggcgccct cctccgccac ccccgacgcc ctcaccctca cctccctcac
    15901 tttcgcctat ggccccacca gcgctcccgt catcgaggac ctcaccgtcc gcgtcgccca
    15961 gggcacccac ctcgccgtcg tgggccccag cggcatcggc aagtccaccc tcaccgctgt
    16021 cgtcgcgggc ctcctggacc cccggcacgg cacggtccac ttgtgtgggc acccggtacc
    16081 cggcgacaca gcccgggcac accgggtcct cattccgcag gaggcgtacg tcttcagggg
    16141 atccctggcc gagaacgtcg gcgatctgcg gccgaaaccc ataccggaac gcgaacttcg
    16201 cgccgccgcg gacgccgtgg gactcaccgc tctgatggaa cggctcggcg gccccgaggc
    16261 cgaggtcgac ccgggcgcgc tgtccgccgg ggagcggcag ctcatcgcgc tgacccgggc
    16321 gtatctgtcg tacgcgcccg tcgtcctgct cgacgaggcg acctgtcacc tcgacgcgga
    16381 ggcggaggag cgcgcggagc gtgccttcgt cgagcgcccc ggcaccaccc tggtcgtggt
    16441 cgcccaccgg gtcggctcgg cgcggcgggc ggaccgggtg ctggtcatgg acggccggcg
    16501 cgttgcgtac gggcaccacg acgacctgct ggaacgctca ccgctctacc gcgaactggt
    16561 cctcggcacc cgggagcccg ccgggcagca gccgctacag ccagccctcc ccctgcgaga
    16621 tacggatggc gtcgattctg ttgcgggcgc cggtcttgcg ggtgatggcc gccatgtagt
    16681 tgcgcacggt cccgtgggac aggtgcaggc tcccggcgat ctccgccacc gacgcaccct
    16741 cggcggccag tgacagcacg ctcaactcac gtctggtcag cggcatctgg gcggccttga
    16801 gaaagccgaa gcccagggag tcgtcgacaa aacgttttcc ctgggcgacc tcgcgtatcg
    16861 cggacaccag ccgctcgggc gcgccctcct tgtccacaaa gcccagggcc ccggcctccg
    16921 ccgcccgttt cagcagtccc ggcctgctcg cctgggccag caccagtaat cgcggcgcgg
    16981 ggccggccgc gccgcgcacg cacaggtcgg cgacgggtgg gatgccgtac gcgtccgcgc
    17041 agtccaggtc ggccgcgcag acgtcgggcc ggatcgacct gacccgcttg ccagcgccgc
    17101 gccacgagca gtcgtccacc ttcaactccg gttccccgcg gagccactcc gccaggaccg
    17161 accgcaccag acacgcgtcg tgcacgagaa gtacccggat cacatcgccc cctccagcct
    17221 cacgtttgcc ggttgctccg tcttcgcgcg tgcccattgt tcgcggctgc caccgccacc
    17281 ggccgcgaag atccggccaa cggggtgcgc gggggcgcac agcagcgccc gagcgcaacc
    17341 gaacgcccca actgaggggg catgtcttcg ggcggagggg gtaccgagga cgactcacag
    17401 acggtgagca aaacgagaat ttatgaacac aaagagcaaa aatcctgcac ctgttgaagc
    17461 ttccgaactt cgcttaggct gtccgccgtt tcgtgaagcc gcgcacggcg cgcgggcggg
    17521 gggacccgca cggacgattg ggtagtcagt gcttcttaga accttcggct ggtccttcgg
    17581 cgtcaccgcc gcgggactcg ccttggccgc cgtcctctgg gggtgggagg gcttcgccgt
    17641 ggtggcgatc ctgagcatcc tggagatctc gctgtccttc gacaacgcgg tcgtgaacgc
    17701 gggcgtgctg aagaagatga acgccttctg gcagaagatc ttcctcacca tcggcattct
    17761 cgtcgccgtg ttcggcatgc gtctggtctt cccggtcgtg atcgtcgccg tcaccgccca
    17821 gctcgggccc atcgaggccg tacggctggc gatcgacgac gccgaccggt accagcagct
    17881 ggtcaccgac gcacaccccg ccatcgcggc cttcggcggg atgttcctgc tgatgatctt
    17941 cctcgacttc atcttcgagg agcgcgacca cacctggctg ggcccgctgg agcgaccgct
    18001 ggccaggctg ggccgcgtcg acgggctgtc ggtgtgcatc gcgctgatcg ccctgctggt
    18061 caccgcgacc accatcgcca cgcaggccgc acagcacggc ggcgcgcacg tcgacaagtc
    18121 ggcaacggta ctgctgtccg gcgtcgccgg cctggtcacg tacctcatcg tcgggggtct
    18181 gtcgggacac ttcgagaaca agctcgaaga agaggaggag aaggagcacg aggccgagga
    18241 ggaggcccgc aaggccggca agcagccctc ggtggtcgcg ctcgcgggca aggccgcgtt
    18301 cttcatgttc ctctacctgg aggtgctgga cgcgtccttc tccttcgacg gtgtcatcgg
    18361 cgccttcgcc atcaccaacg acatcttctg gatggcgctc ggcctcggca tcggcgcgat
    18421 gtacgtccgg tccctgacgg tctacctcgt ccggcagggg accttggacg actacgtcta
    18481 cctggagcac ggcgcgcact acgccatcgg cgccctggcc gtgctgctgc tcgtcagcat
    18541 caggtggcac atcaacgagg tcgtcaccgg cctcatcggc gtggccctga tcgccgcctc
    18601 cttctggtcc tcggtgcgcc gcaaccgcgc gctggcgacg gccgagcagg agtccggcga
    18661 gaagtccgag gtgatgtcgg gagtctgacg ccccgacacc cctgaaacag cacctgtggt
    18721 cgtgacctac gaccgcaggt gcttttgcat gcggttccgg cgcttccgcc ggtaaccgtt
    18781 tacacaaaga cgcgtctgtg cccactcctc cattccccca gccggcgctc cctgcaagct
    18841 gaggctcagc accgcgcggc cgttgaccgg ctcacaccgc tctcactagc gtggaatacg
    18901 tttactgccg cctcgctgcc cggacctctc cgactgcctc cccgcagagc cgaaaggaac
    18961 cgcccccagt gtccgaaccg ctccagcgca gatccctgct caagttggcc gtaggcaccg
    19021 cagccaccgg atggctgtgg cagggcgtcg gcaccgccca ggccgccgcc gacgccacgc
    19081 ccaccaccgc gcccccggcc gccggcccgc tcgacacact ggtcttcggg aacaccgcgt
    19141 cggagagcgc gcacggcctg accgccaccc tctccgacgt cgtcacgggc ggcctcgacc
    19201 agcccgcccg cgtgctcaac gtccctgaga gcgcgggctt ctggggcggc acgctgtccg
    19261 cgacgatggc gtgcaggccc aggggcgcca cctacgtcac catcaagctg tggggctcgg
    19321 agagcggcgc ggaactcggc cggctccagc tcttcgccga gggcaagcag gtcggccact
    19381 accatctggg cgccgtcgac cccctcgaca tcgcgagcga ggatccgcgt acgccggagc
    19441 ggttcttctt ccacacgctg ccgctgcccc tcgatctcac cgagggaaag gagtccgtct
    19501 ccctggagat ccggtccatg ggacgaatcg ccgggtacgc cacgtcggcc gactcctact
    19561 acaaggccat ggaaggcccg agccgcacgg tctaccgcct ctacacccac gacgagccgt
    19621 acttcgccct cgccgacggc gacgtcaccg gcaccctgcc gcccacgacc acgcgcacct
    19681 cccccggcag cgagatcgtc gacacgatca acgcccgcat actcgccagg gccgcgtccg
    19741 aggcgtcccg caccagcccc caactcgacc tgtggtacct ggacttcctg gcccgcgcgt
    19801 acggcatgcc ggctacggcc gcccacgcga acatcgccgt tccgccgcag atcgcgcgga
    19861 gcctcgacgg catctactgg agataccgtg ccgactccgc cgtgatgacc aactccagcc
    19921 agcagtggat gggcctgggc cggtcgggcc tggtcatgct ggcgctcgcc gacgttctgg
    19981 cgccgctgct cgacgagccg gtcctcggtt cgccgtacgg cctcaccaac ccgggcttcg
    20041 agttcggcac cacgggctgg aggtcgtcca cctggtccgg cagcggcacc gcgtcccggg
    20101 acaccaccgt gtaccgcacc ggccacgcct ccgcgaaggt gacggtcccc accgcgggca
    20161 cggtcggcta caccacctcc gccaggatcc cggtggacca gggcacttac acctacggcg
    20221 ggtggatcag gaccgccggc gtcggcaccc gcagtgccta cctggacatc ctcttccacg
    20281 acgcgaacgg cgccgtcgtc ggcaccgaca acaaggtcca cgcctcggcc ggcacccatg
    20341 actgggagca tgtgacggcc tccctcacca caccgggcac ggccacccac gtcaccctca
    20401 gcgtccgcct gtcgggcgcg ggcaccgcct ggttcgacga cctgaccatg gtcgagccgg
    20461 agggctcggc gtacgcgccg gtcgtccgcc gggacgcctg ggccaggatg ctgctggaca
    20521 gccgcgagta ctggcggcag aacttcccgc agtacacgaa ccaggccatc atctgcgcca
    20581 tcggcctcta cctcgccgac cgcggactca cctacctcgg ctcggccgac gcctggggcg
    20641 agaagaaggc ccgcgactac atctaccagt ccgtcggcct cgtcccctgg ctcggcccgg
    20701 agaagccgga cggcaccccg accagaccgc tgggcggctc gtaccaccag gtcaccaaga
    20761 agggcatctc caaggagctc ggctacgcgg gcagttacgg cgagctgcag gagtggctgt
    20821 cgctggtgta cgacgcggtg acgggcatcg gcggcgtcga ggacggcact ctccgcgacc
    20881 acctggtcaa gatggccaag gcgcgcatgg tcttccgcca cccgtcactg gaccgcgacg
    20941 gccaccgggc gatgcgcctg gagaccgtcg tcggatggcg tgacaacgag tacccgggca
    21001 aggtcgccta cgaccaggac gccaagtggg acggccatgc cctgaagatg gccgcgcaga
    21061 tcaaggaccc tgacctcgtc tcgtacgcgc ggcagtccct cgcggacggc caggcgttcc
    21121 agtccctcgc cgactcccac gcggcgacgg tctccgcccg gaccaacctc aatctgctga
    21181 gcaccgccga cgactacgcg tacatcagca aggccaccgg cagtggggcg aagctgccga
    21241 tgacgcccgg ggcaccggac ttcgtcttct ccgacgagga gaacggcctg gtcgcgatca
    21301 agcacggcga cgagatcctg ttcgcgtccc tgtactggcg ggcccgctgg ggcgtcaacc
    21361 ggctggcccg cgtccatcac ctcacggccg agggcaccga gcggtcggcc accgtctggc
    21421 aggaggtcaa gtacctcgcg gacgggcgga cgttcactga accggactgg gtcaactggg
    21481 agttcacggt gagcgacctc gacatcccgg acggcggttt caccccgccc ggcaacgccc
    21541 tgcaccaggc gttcgcgggc caggtgctgc cgctggccaa ggcgccggac gacgtgccgg
    21601 agcgggccgc gggcgtcgag agcccctacg ccggacgcgc ctccttctac cggtgcgagt
    21661 acggcccgta tctgatcgcc atgaacacca ccgacgaccg tgaccacacc ttcaccacgc
    21721 gggggttcgg cgcgtcgacg aacctggtga ccggggcgaa ggtgagcgga aacaccgaag
    21781 tacgcgtgaa gcccggcacg acggtggtgc tgcgcaagcg ctgagtcttc cggcggagtc
    21841 cgatgaacgg ccatgtcgcc ccggtcgcgc gcggggcgcc acggccgtgg cccccgagct
    21901 cgtcccagtg gagtcccgac ggcggaaaac gtttgttgcc ccctcacgtc ggtcgttctc
    21961 cggcggctgc cgcaaggcgc cccacatgca gtaacgtcga gccgtgacgg acagcggcaa
    22021 ccccgagcgc cccggccccc gaaggggccg agccgggaaa cggaagcgga ccgacgcgcg
    22081 gcaggggccc aaggagaggc cgagcaccat ccgtgacgtc gccctcaagg cgggggtttc
    22141 ggtagcaacc gtttcccgca ccctggcggg gaactacccc gtctccgacg aaacccgggc
    22201 ccgcgtcatg gcggccgtcg agtcactgca ctacgtggtc aacgtgcacg ccaaggcgct
    22261 ctccgggcgg gtcgcgggcc cggtcgccct ggtcatcaag gacatcaccg ggccgtcgct
    22321 cgcccacgtc gccgccggag tcgagcaaga ggccgccgac cggggcaggt tgagcctggt
    22381 gtgcgccacg cgcgacgacc cggcccgaga ggacgacctg gtccagctca tgcgggagca
    22441 gcatgcggct gccgtcctcc tcgtcggcgg tgtggtgccg gacgcggcgt acgaccggcg
    22501 catggcgggc tacgcggagg cgctggacgc cgcgggctcg cgactggtgc tggtcggccg
    22561 tccggcgccg gcaccggacc tgccggtgac cgtcgtggac tacgacaacc ggggcggcgc
    22621 cttccaggcc gtctcgcacc tgctcgcgtc cgggcaccgg cgggtgctgt tcctcggcgg
    22681 ggaggccggg ctgagcagcg cggacgagcg ccgggccggg taccgggacg cgctgcgcgc
    22741 gcacggcgcc gaccatg
//
