LOCUS       NZ_KQ947987            22982 bp    DNA     linear   CON 21-APR-2024
DEFINITION  Streptomyces curacoi strain DSM 40107 PRJNA299217_s004, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ947987
VERSION     NZ_KQ947987.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces curacoi
  ORGANISM  Streptomyces curacoi
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 770615)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Draft genome sequence of Streptomyces curacoi DSM 40107, type strain
            for the species Streptomyces curacoi
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 770615)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-OCT-2015) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 13-OCT-2014
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 65.7x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001513975.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 02:05:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,531
            CDSs (total)                      :: 7,455
            Genes (coding)                    :: 7,251
            CDSs (with protein)               :: 7,251
            Genes (RNA)                       :: 76
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 204
            CDSs (without protein)            :: 204
            Pseudo Genes (ambiguous residues) :: 0 of 204
            Pseudo Genes (frameshifted)       :: 91 of 204
            Pseudo Genes (incomplete)         :: 154 of 204
            Pseudo Genes (internal stop)      :: 21 of 204
            Pseudo Genes (multiple problems)  :: 54 of 204
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:06:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 442829
            Orig. end                         :: 465811
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ947987.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22982
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /product="terpene"
                     /region_number="5"
                     /rules="AfsA"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22982
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="neighbouring"
                     /product="butyrolactone"
                     /product="terpene"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10948
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10948
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5948](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5948
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     gene            156..809
                     /locus_tag="AQI70_RS15415"
                     /old_locus_tag="AQI70_15410"
     CDS             156..809
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675693.1"
                     /locus_tag="AQI70_RS15415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15410"
                     /product="hypothetical protein"
                     /protein_id="WP_062149300.1"
                     /transl_table=11
                     /translation="MRTRTLLTLAGAVAALTLPMAVPASAADGAVLTTGSVGGTAVAVG
                     EVLTAPLASGTAATFYSSATGTSGISCTKSQFTAAVTDNPGAPGTATESVTEHTFDPSS
                     CTANVVGVLGVTGITVNNLPYTAAVASDGTVTVTPAEGSTIQTTVVLRTLLGSINCVYQ
                     APSLTGTASNDDNSINFTRQQFTKVSGSSLCFANGYFTAKHAPVTGSGERVYVN"
     cand_cluster    823..22982
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    823..22982
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10822:12982](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      10823..12982
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     gene            complement(828..1787)
                     /locus_tag="AQI70_RS15420"
                     /old_locus_tag="AQI70_15415"
     CDS             complement(828..1787)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010034207.1"
                     /locus_tag="AQI70_RS15420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15415"
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_062150075.1"
                     /transl_table=11
                     /translation="MPWTRSHRTALAAASLTPLLLTVWAAGPARAHGAPTDPVSRVYAC
                     SPDGSGTSRSAACRAAVASNGAPFTAWDNLRIANVNGRDRQTVPDGQLCSGGLPAYQGL
                     DLARADWPSTRLTPGATLTMRYVSTIPHSGTFRLYLTEPGYDPTKPLSWSDLPEQPFAE
                     VTDPTLTDGAYRIRAKLPSDRAGRHVLYTIWQNSSTPDTYYSCSDVVFPAGGSGGAEES
                     GGGGAASATASAGRDDSRTAGGPSPASKPRTAASPTTPPAAGAATTRTQDGPAPDSTPV
                     ASTGGTGVSPSAPVLAGGAAAVLVLTGGAALALRLRRR"
     misc_feature    1844..1853
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            2152..3963
                     /locus_tag="AQI70_RS15425"
                     /old_locus_tag="AQI70_15420"
     CDS             2152..3963
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020122073.1"
                     /locus_tag="AQI70_RS15425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15420"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_062149303.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 2.1e-52, bitscore:
                     173.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTSAPLRRKLIPVAAVSAALFTAATTVAVAQDSTTPEAAASVPA
                     AQTEAAPGTPAERLIVGYKSGAAEAKSNKAAEADAAAKGKEAGEDLDFQRRLGSGAALV
                     DLGENLTKRDVADVVAEYRADPQVAYVVPDRLNKPLATPNDTEYSKQWDLFETTAGMNV
                     PGAWDVATGTGVTVAVIDTGYVSHSDLGANIVAGYDFISDTAVAGDGNGRDSNPADPGD
                     FTAANQCQAGDPAYPSSWHGTHVAGTIAAVTNNSKGVAGIAHGAKVSPLRVLGKCGGYD
                     SDIIDAITWASGGTVSGVPANTNVAKVINMSLGGGGACSTATQNAINAAVNRGTTVVVA
                     AGNDNSNAANYSPASCNNVISVAAADRQGNRSYYSNYGTVVDIAAPGGETNSVTANGIL
                     STLNSGAQGPSTENYEYYQGTSMAAPHIAGLAALMKSANSSLTPAQIESAIKTNSRALP
                     GTCSGGCGAGLADAAKTVQAVSGSGGGSTGGTTFTNSTAVSIPDNGSAIESSIAVSGRS
                     GNAPSALQVGVDITHTYRGDLVIDLIAPDGTSYRLKAASSSDSADNVNTTYTVNASSEA
                     ANGTWKLRVQDTAAQDTGRLNSWKLTF"
     gene            complement(4129..4806)
                     /locus_tag="AQI70_RS15430"
                     /old_locus_tag="AQI70_15425"
     CDS             complement(4129..4806)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996938.1"
                     /locus_tag="AQI70_RS15430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15425"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_062149306.1"
                     /transl_table=11
                     /translation="MARQERAIRTRRLILEAAGAVFDEHGYTATTIAMVLERAEVTKGA
                     LYFHFPSKESLAQAVLDEQLPLGAVPAQSCKLQELVDMTFVFGQRLLNNALLKGSVRLA
                     VDQAAPSGVDHAGPFRQWADHLVVLLEQARDQGELLPTVDPRKTVELLVGAFAGIQLMS
                     RALTDRSDLAERISVLWGHILPSIAVPGLLIGIDRKPDRGERILASLDETGVDTTAVDL
                     SLR"
     gene            5001..5948
                     /locus_tag="AQI70_RS15435"
                     /old_locus_tag="AQI70_15430"
     CDS             5001..5948
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996937.1"
                     /locus_tag="AQI70_RS15435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15430"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_062149309.1"
                     /sec_met_domain="AfsA (E-value: 6.1e-24, bitscore: 79.2,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHLPQLATTTTPLAKAPTLPGGLTATVPRQLVHRASVAETFLTD
                     WAAIDADRFTVTAQWPRAHQLHVSPDRSAHEPLLVAETVRQAGSLLAHTAYDVPLGHQF
                     VLRELRVTTRPEHLAVGAVPAEPVLHVTVTDLDHRGGRPAGFRYDTDVRIGGELVATAS
                     IAAIWTSEPVYRRLRGGRTAATVSALPVPPGLPPAVVDRALPADVVLARSDRPDRWQLR
                     VDTAHAVFFDHPLDHIPGMLLLEAARQAVRALPGNGGRTPVSFRAVFHQYAELDRPTWI
                     EATETADAGGTAVQVVGRQEDSTVFECEVGTEER"
     misc_feature    5196..5198
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6019..6666
                     /locus_tag="AQI70_RS15440"
                     /old_locus_tag="AQI70_15435"
     CDS             6019..6666
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996936.1"
                     /locus_tag="AQI70_RS15440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15435"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_062149313.1"
                     /transl_table=11
                     /translation="MARQLRAEQTRTTILTAAAELFDRHGYESTSLSDIVEHAQVTKGA
                     LYFHFAAKEDLAQAIMELQSRAARQVAAEMDARGQSSLEALIRTTFGITRLSVEGPIPR
                     AGLRLATGGVVIRPPLRHPYTELLDIATRKLLGAAKESDIHPDVDAEAAAHSLVCFFVG
                     TRVVGRSLEPVARQPRRVAEMWHIMIRGLVPVPRRARYLALATQLERELRAV"
     misc_feature    6031..6033
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6689..7876
                     /locus_tag="AQI70_RS15445"
                     /old_locus_tag="AQI70_15440"
     CDS             6689..7876
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996935.1"
                     /locus_tag="AQI70_RS15445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15440"
                     /product="damage-control phosphatase ARMT1 family protein"
                     /protein_id="WP_062149316.1"
                     /transl_table=11
                     /translation="MPERSDIPPAPVLLGNEPGSFPHSVLAERHPAIIRQVRESFPYGP
                     ERHRVLDALLASCTKGVIEPLPADAPDRDRWTAWGADAHTGRSWFDVPWLWSESYFYRQ
                     LLEAVGYFTPGPWQGIDPFRPAKLAELDAPETDEELAALDALADRPAAEQDRALLHGSL
                     WGNRADLGFRLSAAHDETSSHAPPLVADDSEALWSLLPPEGSATLCLIADNAGRELVPD
                     LLLIARLLTQGRIARAVLHVKPYPYYVSDATHTDVLDALRRLTAAPGAAATYGRTLWSA
                     MTDGRLTVRAHPFSSAPLPFAAMPGDLREELAAATLTIVKGDLNYRRLVGDRLWPPTTP
                     FTDVTAHFPGPVAALRTLKSDVVTGLDAGTEAALVAAEGQTWRTGGTHALIQVRM"
     gene            complement(7897..8046)
                     /locus_tag="AQI70_RS39160"
     CDS             complement(7897..8046)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AQI70_RS39160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159042665.1"
                     /transl_table=11
                     /translation="MRSRRRRVFAPRQYATGVPYDACRVLRDHHPVARQDEPHGIKSPL
                     VRIT"
     gene            8097..8579
                     /locus_tag="AQI70_RS15450"
                     /old_locus_tag="AQI70_15445"
     CDS             8097..8579
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012738.4"
                     /locus_tag="AQI70_RS15450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15445"
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_244181641.1"
                     /transl_table=11
                     /translation="MLQFARAVPPPALVPVFVVIFDFGTPMQIASIVFSAVWPVLINTA
                     EGARDTDPLRLEVAAVLRLTPAERLRFLILPSALPRVFAGLRLSLSLSLILMVFSELLP
                     GTANGIGFTLTDAQSRSGLLTVWAALVLLGALGHLLNTGLLAVEKRLVGRGRTTTV"
     gene            8626..9375
                     /locus_tag="AQI70_RS15455"
                     /old_locus_tag="AQI70_15450"
     CDS             8626..9375
                     /EC_number="7.6.2.14"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062773.1"
                     /locus_tag="AQI70_RS15455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15450"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_062149319.1"
                     /transl_table=11
                     /translation="MLRLAAVGRHYSDHQVLHDITLTVPHGQLLCVVGPSGCGKSTLLR
                     TIAGLLPTHDGTITLDGTPVRGVPDHLAVVFQDHARSLYPWLTVRENVALPLRRRGLPR
                     AQRRAEADRILDRVGLTGAARRHPWQLSGGMQQRVAIARALVCRPSLLLMDEPFGYLDA
                     QTREDLEDLLLEVHRTDGTTIVLVTHDIDESVYLGDRVVVLSPGPGAKVVLDLPVELPG
                     ARDQIATRGLAEFVALRSEVGRAVRNR"
     gene            complement(9400..10638)
                     /locus_tag="AQI70_RS15460"
                     /old_locus_tag="AQI70_15455"
     CDS             complement(9400..10638)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071446.1"
                     /locus_tag="AQI70_RS15460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15455"
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="WP_062149322.1"
                     /transl_table=11
                     /translation="MNHTGSFSRRVALASLAGAALAGTAAFPASATGGHRRTVRFATFN
                     ASLNRSAQGALITDLSTPDNAQARNAAETIQRVDPDVLLINEFDHDEQGTAVRLFLRNY
                     LSVGQGGAKPVRYPYHFTAPVNTGVASGVDLDGKNGAVTTPGSDAYGQDAYGYGWFPGQ
                     YGMVVLSKYPIDTRAVRTFQRFLWRDMPGHLMPPGYYSDEARAILRLSSKSHWDVPVCV
                     GRSTVHFLVSHPTPPTFDGTEDRNGRRNHDEIRLWADYIGGRRRSSYLYDDKGVRGGLR
                     PGAWFVIAGDQNADPYDGDSHGHAIRQLLDHPAVNLPAAPPAGAGGVEAAKLQGGANTS
                     HTGDPAYDTADFGDGAPGNLRVDYVLPSKGLIPGANGVFWPTSDDPLYRLVGDGRTVPT
                     SDHRLVWQDVRLG"
     misc_feature    10705..10716
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    10743..10758
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.21"
                     /tool="antismash"
     gene            10823..12982
                     /gene="cyc2"
                     /locus_tag="AQI70_RS15465"
                     /old_locus_tag="AQI70_15460"
     CDS             10823..12982
                     /EC_number="4.1.99.16"
                     /EC_number="4.2.3.22"
                     /EC_number="4.2.3.75"
                     /codon_start=1
                     /gene="cyc2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996932.1"
                     /locus_tag="AQI70_RS15465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15460"
                     /product="germacradienol/geosmin synthase Cyc2"
                     /protein_id="WP_062149325.1"
                     /sec_met_domain="T1TS (E-value: 2.8e-80, bitscore: 266.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQQPFELPHFYMPYPARLNPHVDEARAHSTEWAREMGMLEGSGI
                     WEQADLDAHDYGLLCAYTHPDCDGPALSLITDWYVWVFFFDDHFLETFKRTQDRVGGKA
                     YLDRLPLFMPMDLSTPMPEPENPVEAGLADLWARTVPSMSVDWRRRFAVATEHLLNESL
                     WELSNINEGRVANPVEYIEMRRKVGGAPWSSGLVEYATAEVPVSVAGSRPLRVLMETFS
                     DGVHLRNDLFSYQREVEDEGELSNGVLVLEKFFGCTTQEAADTVNDVLTSRLHQFEHTA
                     LTEVPAVALEKGLSPEEVAAVAAYTQGLQDWQSGGHEWHMRSSRYMNERAEPTAPWRGP
                     TGPGTSAADVGALLAAAGAERLRAYTHVPFQKVGPSRLPDFHMPFQVQLSPHLNDARHR
                     LTQWTHRMGMLQEGVWDEDKLAAYDLPLCSAGLDPDATPEALDLSSQWLAWGTYGDDYY
                     PLVFGHRRDLAAARLTTRRLSACMPLDGEEAIVPLNGMERGLADLWARTTAEMTPDGRR
                     TLKDAVDVMTESWVWELSNQLQNRIPDPVDYLEMRRATFGSDLTLSLCRMGHGPAIPPE
                     VYRSGPVRSLENAAIDYACLLNDVFSYQKEIEYEGEIHNAILVVQNFFGIDYPAALDVV
                     HDLMTQRMQQFEHVAAHELPIMYDDFGLSDEARDIMRSYVVDLQNWLAGILNWHREVDR
                     YKAEYLARRAHGFLPDRPPAVPVLS"
     misc_feature    13217..13230
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
     gene            13217..15103
                     /gene="phsA"
                     /locus_tag="AQI70_RS15470"
                     /old_locus_tag="AQI70_15465"
     CDS             13217..15103
                     /EC_number="1.10.3.4"
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0050149 - o-aminophenol oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0017000 - antibiotic biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="phsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675701.1"
                     /locus_tag="AQI70_RS15470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15465"
                     /product="O-aminophenol oxidase PhsA"
                     /protein_id="WP_062149328.1"
                     /transl_table=11
                     /translation="MTDIIERFTDSDRETGAQERPLDSGELTPYLAPLPVPPVLRPASD
                     DVLRETEIALRPAWVRLHPQLPPTLMWGYDGQVPGPTIEVRRGQRVRIAWTNRIPKDSE
                     YPVTSVEVPLRRDGRPQATTEPGRAGVEPNKDVAALPAWSVTHLHGAQTGGGNDGWADN
                     AVGYGDAQLSEYPNDHQAVQWWYHDHAMNITRWNVMTGLFGTYLVRDDEEDALHLPGGE
                     REIPLLLADRNLDTDEDGRLNGRLLHKTVIVQEKNPETGKPVSLPFTGPYTTVNGRIWP
                     YAEVDDAWYRFRLVNASNARIYSLVLVDEDDNPVPGIVHQIGSDGGLLPRPVPIDFDGA
                     MPTLSAAPAERFDLLVDFRGLAGRTLRLVNKGRNQPPGVPDPAGDVRYPAVMEFRVRET
                     CETDTFELPEVLSGSFRRLTHDIEHGHRLIVLTPPATKGAGGHPEMWEMAEVEDPGDIQ
                     VPTEGVIQITGPNGRTRTYRRTARTFNDALGFTIAEGSHEQWSFLNLAPIVHPMHIHLA
                     DFQLLGRDAYDVSGFDPAVGGTRSPIRYDARTRIPLAPNELGHKDVFQVPGNQMLRVMG
                     RFDGAYGRFMYHCHLLEHEDMGMMRPFVVMPAEALKFDHGGAHGGHGEGHTG"
     gene            complement(15132..15875)
                     /locus_tag="AQI70_RS15475"
                     /old_locus_tag="AQI70_15470"
     CDS             complement(15132..15875)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431963.1"
                     /locus_tag="AQI70_RS15475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15470"
                     /product="hypothetical protein"
                     /protein_id="WP_062149331.1"
                     /transl_table=11
                     /translation="MTNTAARTVKTARLALVGDRSPNVASHTRVPLLLEALAERDRLVL
                     DAYWIPSRDAAADDAVRGFDAVWVLPGSPYDSEAGVLSAIRTAREEGIPFLGTCGGFQH
                     ALLEYARHVCGLTRVAHAETDPDAEDFLIEPLACSLVGHEAAVRIEPGSLAQSVMGAER
                     TVERYFCAYGPSRHLDTLRAHGLRFSGHDEDGHVRIAELPGHPFFLASLFQPELSGDGS
                     RPHPVVRALARAAVEHAARRVPTHA"
     gene            15971..16834
                     /locus_tag="AQI70_RS15480"
                     /old_locus_tag="AQI70_15475"
     CDS             15971..16834
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010360992.1"
                     /locus_tag="AQI70_RS15480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15475"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_062150077.1"
                     /transl_table=11
                     /translation="MDPHLLRTYVTVARLASFSDAARELGYTQSAVSQQIAALEQDLGA
                     PLLTRRPVAPTAAGDRLLEHAGPLLLRLDAARADVVRMAAAPEHGLTLATAATALAPRV
                     LAALPPSGVTLRVLPRDEVPAAVATGTADLGLVDGLAAPSDPLRLPDVAPLTTYGVGEE
                     PVRVLLPDTHPLAHRTGLRLGDLADARWLDAPDAGLPLAQLRAANGGQGFRRAMRYEGT
                     DVRTLTALAAAGHGLTLLPCSAATEVPGTVAVPVVEPRVVHRTELVYAGAPGGAAAVAE
                     ALVGRL"
     gene            16989..17585
                     /locus_tag="AQI70_RS15485"
                     /old_locus_tag="AQI70_15480"
     CDS             16989..17585
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015657043.1"
                     /locus_tag="AQI70_RS15485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15480"
                     /product="PDZ domain-containing protein"
                     /protein_id="WP_062149334.1"
                     /transl_table=11
                     /translation="MEHTALRPKPMPGQPPGDGARTDPGARRPHTAPRRCGRRLTALLP
                     ALLVGLALVLSGVGLGTVGATVIGMSRLAELQRQTGPDTPATPAPSAQPGSSAAPSPTP
                     ASSPAPAAATLGVEAVDAGRPGALVVGLHVPGPGYTAGLVRGDLILAFDRTRVDSAADL
                     ARAVAGTRPGRVVTLTVRHRNGGYQQLRAVPGVVT"
     gene            17668..18288
                     /locus_tag="AQI70_RS15490"
                     /old_locus_tag="AQI70_15485"
     CDS             17668..18288
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385486.1"
                     /locus_tag="AQI70_RS15490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15485"
                     /product="LysE family translocator"
                     /protein_id="WP_062149337.1"
                     /transl_table=11
                     /translation="MLTTLVAFLGACTLVAASPGPSTVLIIKQSLHSRRSGFLTVLGNE
                     TGVFIWGIVAAFGLTALLTASEVAYDVMRIVGAVVLVGFGIQALRQARRTEGAEQDAWQ
                     GVHKSGWASYRGGLLLNLANPKAAVFALSFLPQFVPEGAPHLPTMIGLAALWAVYEVGY
                     YGLYVWFVGRMKAVLSRAGVRRRLEQISGGVLLLLGVRMALEN"
     gene            18397..19524
                     /locus_tag="AQI70_RS15495"
                     /old_locus_tag="AQI70_15490"
     CDS             18397..19524
                     /EC_number="3.4.11.9"
                     /GO_function="GO:0004177 - aminopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0070006 - metalloaminopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1172: methionine aminopeptidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996926.1"
                     /locus_tag="AQI70_RS15495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15490"
                     /product="aminopeptidase P family protein"
                     /protein_id="WP_062149340.1"
                     /transl_table=11
                     /translation="MTGTAPAPFTADDYRARMERAARTAADAGLAGLLVAPGPDLVWLT
                     GYAPTAETERLTLLVLVPGQDPVLVVPALEAPDAAKAAGAPGLTLRDWTDGKDPYAATA
                     ALLEASGRFGISDNAWAMHLLALQRALPGASYASLTDALPMLRAVKDAAELELMAAAGA
                     AADATFEEIRKVPFGGRRESEVAADLADLLRHFGHSQVDFTIVASGPNGANPHHEVGDR
                     VIERGDMVVLDFGGLKDGYGSDTSRTVHVGEPTDEERRVHDLVREAQEAGFRAVRPGVA
                     CQEVDRAARAVIADAGYGEYFIHRTGHGIGVTTHEPPYMIEGEEQPLVPGMCFSVEPGI
                     YLPGRFGVRIEDIVTVTEDGGRRLNDTTREMVIVD"
     gene            19586..20530
                     /locus_tag="AQI70_RS15500"
                     /old_locus_tag="AQI70_15495"
     CDS             19586..20530
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996925.1"
                     /locus_tag="AQI70_RS15500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15495"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_062149343.1"
                     /sec_met_domain="APH (E-value: 5.3e-18, bitscore: 61.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQAPTPTADTVRRLVRSLLKEGVDDSAGPEVRPAAPGADPATWL
                     VGTRHVLRLAPDRAAAARQRRELRLRDLVRPHVPVAVPTSVAHGEWAPGLTYTLDTKVP
                     GGSGGEHDVSAVGEADLAGLLTGLREVPVRQAETLGVPRAAPRSLEALRRAAETAAGRL
                     AAADEFDAARLRQLTQPAAVQLAAQPNTAVLVHHALTGDHLVVSADGRVRGVLGWADTV
                     LGDPAEDIAGLALAVGSPAAVRAATLAGYSARPCLRGLWLARCDAVVRLANRLDGKGGT
                     PPQVLRAQLRNAWEAILLERVTELRDDEADGEL"
     gene            complement(20600..22345)
                     /gene="treZ"
                     /locus_tag="AQI70_RS15505"
                     /old_locus_tag="AQI70_15500"
     CDS             complement(20600..22345)
                     /EC_number="3.2.1.141"
                     /GO_function="GO:0033942 -
                     4-alpha-D-(1->4)-alpha-D-glucanotrehalose trehalohydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0005992 - trehalose biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="treZ"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Alpha-amylase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1297: Pullulanase, type I"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133692.1"
                     /locus_tag="AQI70_RS15505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_15500"
                     /product="malto-oligosyltrehalose trehalohydrolase"
                     /protein_id="WP_062149346.1"
                     /sec_met_domain="Alpha-amylase (E-value: 3.9e-12, bitscore:
                     41.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFEVWAPQADRVTLHCEGTTRALERDPDRAGWWWGEAEARDGTR
                     YGFALDDGPVLPDPRSRRQPDGPDGLSAVVDHGRYAWRGEWAGRPLPGAVLYELHVGTY
                     TREGTLDAAAERLGHLAELGVTHVELMPLSPFPGRHGWGYEGVSLWAVHEPYGGPEALK
                     RFVDRAHELGLGVVLDVVHNHFGPSGNHLPAFGPYLTDTHQTPWGAAVNLDAPGSDEVR
                     AYLVQSALAWLRDYRLDGLRLDAVHALVDTRACHFLEELSTAVDALAAGLGRPLFLIAE
                     SDLNDPRLITAREEGGLGLHAQWNDDFHHAVHTALTGESQGYYADFARAPMAALAKTLT
                     GGYFHDGTYSSFRGRSHGRRLDRARVAAHRLLGYSQTHDQVGNRAQGDRLAALLSPGLL
                     ACAATLTLTAPFTPMLFMGEEWAAGTPWQFFTDHTDPELAEAVRRGRRREFAAHGWAED
                     EVPDPQDPATRERSCLDWSEPAGEPHARVLAWYRRLIALRHEHPDLTDPDLADTKVAYD
                     EHERWLAFRRGDVRVAVNLAKEPAAIPLGPRRAEVLAAWEPVAAPGADGVLHVPGESGV
                     VLLQA"
ORIGIN
        1 ggccggcctc cggtcggctg ccgttgccgg tccgtcacgt acggagaagg cgtcacgggc
       61 cggcagcggc gcacgccgac ccaagcgccc cacactcccc gaactccctg atcccctcag
      121 ggcacacccc ccaacgaaag ccgaggtaca cccgcatgcg cacgcgcacc ctcctcaccc
      181 tcgccggcgc cgtcgccgcg ctcaccctcc ccatggccgt ccccgcgtcc gcggccgacg
      241 gcgccgttct caccaccggc tccgtcggcg gtacggccgt cgcggtcggc gaggtcctca
      301 ccgcgccgct ggcgagcggc accgccgcca cgttctactc cagcgcgacc ggcaccagcg
      361 gcatctcctg cacgaagtcg cagttcaccg ccgccgtcac cgacaacccc ggcgccccgg
      421 gtaccgccac cgagtcggtc accgagcaca ccttcgaccc cagcagctgc accgccaacg
      481 tcgtcggcgt gctcggcgtc accggcatca cggtcaacaa cctgccgtac accgccgccg
      541 tggcctccga cggcaccgtc accgtgaccc cggccgaggg ctccaccatc cagacgacgg
      601 tcgtgctgcg caccctcctg ggcagcatca actgcgtcta ccaggcgccc agcctgaccg
      661 gcacggcgag caacgacgac aacagcatca acttcacccg tcagcagttc acgaaggtct
      721 ccggctcgtc cctgtgcttc gccaacggct acttcaccgc caagcacgcc ccggtgaccg
      781 gcagcggcga gcgggtctac gtcaactgac gtcttgggta tgggagttca cctccgtcgt
      841 agacgcagtg ccagggcggc gcccccggtg agcaccagca ccgcggcggc gccgcccgcc
      901 agcacgggcg ccgaggggct cacaccggtg ccgccggtgg aggccaccgg cgtgctgtcg
      961 ggggcggggc cgtcctgggt gcgcgtcgtc gcggccccgg ccgcaggggg agtcgtgggc
     1021 gaggcggccg tacgaggctt gctcgcgggt gaagggccgc cggccgtacg gctgtcgtcg
     1081 cgccccgcgc tcgcggtggc cgaagcagca cccccgccgc cgctctcctc ggcgcccccg
     1141 ctcccgcccg ccgggaacac cacgtccgag cacgagtagt acgtgtccgg agtgctgctg
     1201 ttctgccaga tcgtgtacag cacatggcgc ccggcccggt cggacggcag tttcgccctg
     1261 atccggtacg ccccgtccgt cagcgtcggg tccgtcacct ccgcgaacgg ctgctccggc
     1321 agatcggacc agctcagcgg cttcgtcggg tcgtagccgg gctcggtgag atagagccgg
     1381 aaggtgccgc tgtgcgggat cgtcgagacg taccgcatcg tcagggtggc gcccggcgtc
     1441 agacgggtcg acggccagtc ggcgcgggcg aggtcgaggc cctggtaggc gggcagtcca
     1501 ccgctgcaca gctgtccgtc ggggacggtc tgccggtccc ggccgttcac gttcgcgatc
     1561 cgtaggttgt cccaggccgt gaagggcgcc ccgttcgacg ccaccgccgc ccggcacgcc
     1621 gcagaccggg atgtgccgct gccgtcgggg gagcaggcgt acacccggct gaccggatcc
     1681 gtcggcgcac cgtgcgcccg ggccgggccg gccgcccaca ccgtgagcag caacggcgtg
     1741 agtgaggcgg ccgccagggc ggtgcggtgc gatctcgtcc agggcatcca ggacatccgg
     1801 aacgtctcct cggccggagt gggaaggtcc tcgtccagta cgggaaggcg gcccggcgcg
     1861 ttcaccacgc gacgagccgg gcgaaatccg tcattgccgg tcaaccgtcc gacgtagagg
     1921 gtgggtttcc ggcccgatcg agggtttccc ctgtatccct gtgacctcct ctttgcctat
     1981 cgttcgacca cagccgaccc acaggtaacc ccgaacaggt cgtagctcgc gccaggccgg
     2041 ccgccgcgcc cccgcacttt cgatacaccc cccgccgctt cgaggacgaa gcgcaatcga
     2101 ccgccgctcc gcgctgcccg gagtacggcc ggccccacga aaggcaagcc cttgcgtacc
     2161 tctgcacccc tcagacggaa gctgataccc gtcgccgcgg tctccgccgc gctcttcacg
     2221 gccgccacca ctgtcgccgt ggcccaggac tccaccaccc cggaagccgc cgcctccgtc
     2281 ccggcggccc agaccgaagc cgcacccggc accccggccg agcgcctcat cgtcggctac
     2341 aagtccggcg ccgccgaggc caagtcgaac aaggccgccg aggccgacgc cgccgccaag
     2401 ggcaaggagg ccggcgagga cctcgacttc cagcgccgcc tcggctccgg cgccgccctc
     2461 gtcgacctgg gcgagaacct cacgaagcgc gatgtcgccg acgtcgtcgc cgagtaccgg
     2521 gccgacccgc aggtcgccta cgtcgtaccg gaccggctga acaagccgct ggccacgccc
     2581 aacgacaccg agtacagcaa gcagtgggac ctcttcgaga ccaccgcggg catgaacgtg
     2641 ccgggtgcct gggacgtcgc cacgggcacc ggcgtgaccg tcgccgtcat cgacaccggt
     2701 tacgtcagcc actccgacct cggtgccaac atcgtcgcgg gctacgactt catctccgac
     2761 accgcggtcg cgggtgacgg caacggccgc gacagcaacc cggccgaccc gggcgacttc
     2821 accgccgcga accagtgcca ggcgggcgac cccgcctacc cctcctcctg gcacggcacc
     2881 cacgtcgcgg gcaccatcgc cgccgtcacc aacaacagca agggcgtcgc gggcatcgcg
     2941 cacggcgcga aggtctcccc cctgcgtgtc ctcggcaagt gcggcggcta cgactccgac
     3001 atcatcgacg ccatcacctg ggcgtccggc ggtacggtct ccggcgtccc ggccaacacc
     3061 aacgtcgcca aggtgatcaa catgagcctc ggcggtggcg gcgcctgctc caccgcgacc
     3121 cagaacgcca tcaacgccgc cgtgaaccgc ggcaccacgg tcgtcgtcgc ggcgggcaac
     3181 gacaactcca acgccgccaa ctactcgccg gccagctgca acaacgtcat cagcgtggcg
     3241 gccgccgacc gtcagggcaa ccgctcctac tactccaact acggcacggt cgtggacatc
     3301 gcggccccgg gcggcgagac caactccgtc accgccaacg gcatcctgtc cacgctgaac
     3361 tccggcgcgc agggcccgtc caccgagaac tacgagtact accagggcac cagcatggcc
     3421 gccccgcaca tcgcgggcct ggccgcgctg atgaagtcgg ccaactcgtc gctgaccccg
     3481 gcgcagatcg agtcggcgat caagaccaac tcgcgtgcgc tgcccggtac ctgctcgggc
     3541 ggctgcggcg ccggtctcgc ggacgcggcc aagacggtgc aggcggtgag cggctccggc
     3601 ggcggctcca cggggggcac caccttcacc aacagcacgg ccgtctccat cccggacaac
     3661 ggctccgcga tcgagtcctc catcgccgtc agcggccgca gcggcaacgc cccctcggcc
     3721 ctccaggtcg gcgtggacat cacccacacc taccgcggtg acctggtcat cgacctgatc
     3781 gcgcccgacg ggacgagcta ccgtctgaag gccgccagct cctcggactc cgcggacaac
     3841 gtgaacacca cctacacggt gaacgcctcc agcgaggccg ccaacggcac ctggaagctg
     3901 cgcgtccagg acacggccgc ccaggacacg ggcaggctca acagctggaa gctgaccttc
     3961 tgagcgacaa ctgagcgcgc ctgaacgggc gcgtacacaa agcgggcggg ccggccggtg
     4021 cggatggggc atcggccggc ccgtcgtctt tcgcgcacgc tcctgcgggg cgggcgcgcc
     4081 gccccgcagg agccccggaa accgtcactc cggtccggta agtcgccctc agcgcaggga
     4141 caggtccacg gcggtcgtgt cgacgccggt ctcgtcgagg gacgccagaa tccgctcgcc
     4201 acggtcgggt ttgcggtcga tgccgatcag caggcccggc acagcgatgc tcggcaggat
     4261 gtgcccccac agcaccgata tccgctccgc cagatcgctg cggtcggtca gcgcccggga
     4321 catcagctga atccccgcga acgccccgac cagcagctcc accgtcttcc tgggatccac
     4381 ggtgggcagc aactcaccct ggtcccgggc ctgttccagc aggacgacca gatggtccgc
     4441 ccactgccgg aacggtccgg catgatcgac gccggacggt gccgcctggt caaccgccag
     4501 ccgcacactg cccttgagca gcgcgttgtt cagcagccgc tgcccgaaca caaaggtcat
     4561 gtcgacgagt tcctggagct tgcacgactg tgccggcacg gcgccgagcg gcagttgctc
     4621 gtccagcacg gcctgggcca gggactcctt ggaagggaag tggaagtaca gggcgccctt
     4681 ggtgacttcg gcccgctcca ggaccatcgc gatggtggtc gcggtgtacc cgtgctcgtc
     4741 gaacaccgcg cccgcggcct ccaggatgag ccgccgcgtt ctgatggcgc gctcctgcct
     4801 cgccataact gcccctccgc atttttcctt cgcccccggg tgcgccggtg tgcgccggtg
     4861 tgcgccggag cgggttcggc acggatccgg gcgaccccag gccgcattga aaacaaaccg
     4921 gtcggctcgt actctaacgc tcgcgacacg ggcgcctcgc cggctgtcag cgcacacacg
     4981 ggggtaccca aggaggggac atgtctcatc tgccgcagct cgccacgacc acgaccccac
     5041 tcgccaaggc cccgacgcta ccgggcggtc tgaccgccac cgtaccccgc cagctcgtcc
     5101 atcgcgcctc ggtcgctgaa acgtttctga cggactgggc cgccatcgac gccgaccggt
     5161 tcaccgtcac cgcccagtgg ccgcgtgctc accagttaca cgtgtcgcca gaccggtcgg
     5221 cccatgaacc gctgctcgtc gcggagaccg tgcgccaggc cggctcgctc ctcgcgcaca
     5281 ccgcgtacga cgtcccgctg ggccaccagt tcgtgctccg ggaactgcgc gtcaccaccc
     5341 gccccgagca tctggccgtc ggtgccgtac ccgccgaacc cgtcctccac gtcaccgtca
     5401 ccgacctcga ccaccgcggt ggccgcccgg ccgggttccg ctacgacacg gacgtccgga
     5461 tcggcggtga gctcgtcgcg acggcgtcca tcgccgccat ctggacgagc gagcccgtct
     5521 accgcaggct gcgcggcggt cgcaccgcgg ccaccgtctc cgcgctgccc gtcccgccgg
     5581 ggctgccgcc cgccgtggtg gaccgggccc tgcccgcgga cgtcgtcctc gcccggtccg
     5641 accgcccgga ccgctggcag ctgcgagttg ataccgcgca tgctgttttc ttcgatcacc
     5701 ccctcgacca catacccggc atgctgctgc tggaggccgc ccgccaggcc gtgcgggccc
     5761 tgcccggcaa cggcggccgg acacctgtct ccttccgcgc cgtcttccac cagtacgccg
     5821 aactggaccg tcccacctgg atagaagcga ccgaaacggc ggacgccggc ggcaccgccg
     5881 tccaagtcgt gggacgacag gaggactcga cggtcttcga gtgcgaggtg ggtacggagg
     5941 agcggtgaga tatcgtgtac gcggagtaag aaacaaacgg catgacccgt tcttttccgt
     6001 cccaggagtg tccagccgat ggcgaggcag ttacgcgccg aacagacccg caccacgatc
     6061 ctcacagccg ccgccgaact gttcgaccgt cacggctatg aatccaccag tctcagcgac
     6121 atcgtcgagc acgcccaagt caccaagggc gccctgtact tccacttcgc ggcgaaggag
     6181 gatctcgccc aggccatcat ggagctccag tccagagccg cccggcaggt ggcggccgag
     6241 atggacgccc ggggccagtc ctcgctggag gcgctgatac gcacgacgtt cggcatcaca
     6301 cgcctgtccg tcgagggccc gataccccgg gccggcctgc gcctggccac cgggggagtg
     6361 gtgatacgac cgcccctgcg gcacccctac accgaactgc tggacatcgc cacccgcaaa
     6421 ctcctcggcg ccgccaagga gtccgacatc cacccggacg tcgacgccga ggccgccgcc
     6481 cactccctcg tctgcttctt cgtcggcacc cgtgtcgtcg gccgttccct cgaacccgtc
     6541 gcacgccagc cccgcagggt ggccgagatg tggcacatca tgatccgcgg cctggtcccg
     6601 gtaccccggc gggcccgtta tctcgcgctc gcgacacagc tggagcggga gctgagagcc
     6661 gtatgacacg cgcgatacgg tgaggcgcat gcccgagagg tccgacatcc cgcccgcgcc
     6721 cgtgctcctc ggaaacgaac ccggctcgtt cccgcacagc gtgctcgccg aacggcatcc
     6781 cgcgatcatc cggcaggtgc gggagtcctt cccctacggc cccgagcggc accgcgtgct
     6841 cgacgcgctc ctggcgagct gcaccaaggg cgtgatcgaa ccgctgcccg ccgacgcacc
     6901 cgaccgggac cgctggacgg cctggggcgc cgacgcccac accggccgat cctggttcga
     6961 cgtaccgtgg ctgtggtcgg agagctactt ctaccgccaa ctcctcgaag cggtcggata
     7021 cttcaccccc ggcccctggc agggcatcga ccccttccgc cccgccaagc tggccgaact
     7081 cgacgccccg gagacggacg aggaactggc cgccctcgac gccctcgcgg accggcccgc
     7141 cgcagagcag gaccgggccc tgctgcacgg ctccctgtgg ggcaaccgtg cggacctcgg
     7201 cttccggctg tccgccgcgc acgacgagac ctcctcgcac gccccgcccc tggtggccga
     7261 cgacagcgag gccctgtggt cactgctgcc gcccgagggc tcggccaccc tgtgcctgat
     7321 cgccgacaac gcggggcgcg aactcgtccc cgacctgctc ctcatcgccc gtctcctcac
     7381 ccaggggcgc atcgcgcggg cggtgctcca cgtcaagcct tacccgtact acgtctccga
     7441 cgccacccac accgatgtgc tcgacgccct gcgccggctc acggcggcac cgggcgcggc
     7501 ggcgacgtac ggccgcaccc tctggtcggc gatgacggac ggccgcctca ccgtccgcgc
     7561 ccatcccttc tccagcgccc cgctgccgtt cgcggcgatg cccggcgacc ttcgcgagga
     7621 gctcgccgcc gccaccctca ccatcgtcaa gggcgacctc aactaccgtc gcctcgtcgg
     7681 cgaccggctg tggccgccga cgacgccgtt caccgacgtc accgcccact tcccgggccc
     7741 ggtcgcggcc ctgcgcaccc tgaagtccga cgtcgtcacc gggctggacg ccgggacgga
     7801 ggcggcgctg gtggcggcgg aggggcagac ctggcggacg ggcgggacgc atgcgctgat
     7861 ccaggtgcgg atgtgacgac caccgtgcgg cttcactcaa gtgatccgca cgagtggcga
     7921 cttgatgccg tggggctcgt cctgccgggc gacggggtgg tggtcgcgca ggacgcggca
     7981 ggcgtcgtac gggacgccgg tggcgtactg gcggggggcg aagacccgcc gtcgccggga
     8041 tcgcactcgg agtcgcggtc ggccgctcgc gccgcgtgta cgccctgtgc aatcccgtgc
     8101 tgcagttcgc ccgcgccgtc ccaccgcccg ccctggtccc cgtcttcgtc gtgatcttcg
     8161 acttcggtac gccgatgcag atcgcgtcca tcgtcttcag cgccgtctgg ccggtcctga
     8221 tcaacacggc ggaaggggcc cgcgacaccg accccttgcg ccttgaggtc gccgcggtcc
     8281 tgcgcctcac cccggccgaa cggctccgct tcctgatcct gccctccgcg ctgccccgcg
     8341 tcttcgccgg gctgcgcctg agcctctcgc tctccctcat cctcatggtg ttctcggaac
     8401 tgctgccggg caccgccaac ggcatcggct tcacgctcac cgacgcccag tcccgctccg
     8461 gcctgctcac cgtctgggcc gcgctggtcc tgctcggcgc cctcggccac ctcctcaaca
     8521 ccggcctgct ggcggtggag aagcggctcg tcggccgggg gaggacgacg accgtatgac
     8581 ccgtacgccc cccaccgccc ctcctgctgc tgcgcaggga catccatgct ccggctagcc
     8641 gcggtcggtc ggcactacag cgaccaccag gtcctgcacg acatcaccct caccgtgccg
     8701 cacggccagt tgctgtgcgt cgtcggaccg tccggctgcg gcaagtccac gctcctgcgc
     8761 accatcgcgg gcctgctgcc gacgcacgac ggaacgatca cgctggacgg cacacccgtg
     8821 cggggcgtcc ccgaccatct ggccgtggtc ttccaggacc acgcccgctc cctctacccc
     8881 tggctcacgg tccgcgagaa cgtcgcgctc cccctgcgcc gcaggggcct gccgagagcc
     8941 caacgccgag ccgaggccga ccgcatcctg gaccgggtcg gcctcaccgg tgcggcccgc
     9001 cgccacccct ggcagctctc gggcggcatg cagcagcgcg tggcgatcgc ccgcgccctg
     9061 gtctgccgcc cctccctgct gctcatggac gaacccttcg gttacctgga cgcccagacc
     9121 cgtgaggacc tggaggacct gctcctggag gtccaccgca ccgacggcac gacgatcgtc
     9181 ctcgtcaccc acgacatcga cgagagcgtg tacctgggcg accgcgtcgt cgtcctctcc
     9241 ccggggcccg gcgcgaaggt cgtcctggat ctgccggtcg aactccccgg cgcccgggac
     9301 cagatcgcga cccggggcct ggcggagttc gtcgcgctgc ggtcggaggt ggggcgggcg
     9361 gtgcgcaaca ggtagcgcgc ccgtcggccc ccccgtcgct cagcccaggc gcacgtcctg
     9421 ccacaccagc cggtgatcgg aggtcggcac cgtcctgccg tctcccacca gccggtacag
     9481 cgggtcgtcg gacgtcggcc agaagacgcc gttcgcgccc ggtatcaggc ccttggacgg
     9541 caggacgtag tcgacgcgca ggttccccgg agcgccgtcg ccgaagtcgg cggtgtcgta
     9601 cgccggatcg ccggtgtgcg aggtgttggc gccgccctgg agcttcgcgg cctccacgcc
     9661 gcccgcgccg gccggcggtg cggccgggag gttcaccgcc ggatggtcga gcagttgccg
     9721 tatggcgtgg ccgtggctgt cgccgtcgta cggatcggcg ttctggtcac ccgcgatcac
     9781 gaaccaggcc ccgggccgca gcccgccgcg cacccccttg tcgtcgtaga gataggagct
     9841 gcgccggcgt ccgccgatgt agtcggccca cagccggatc tcgtcgtggt tgcggcggcc
     9901 gttgcggtcc tcggtgccgt cgaaggtggg cggcgtgggg tgcgagacca ggaagtgcac
     9961 ggtggagcgc ccgacgcaca ccggcacgtc ccagtggctc ttcgacgaca gccgcaggat
    10021 cgcgcgggcc tcgtcgctgt agtagcccgg cggcatgagg tggcccggca tgtcccgcca
    10081 caggaaccgc tggaaggtcc gcaccgcgcg cgtgtcgatc gggtacttcg acagcacgac
    10141 catgccgtac tgccccggga accagccgta gccgtaggcg tcctgcccgt acgcgtccga
    10201 accgggcgtc gtgaccgcgc cgttcttccc gtcgaggtcc accccggagg cgacgcccgt
    10261 gttcaccggg gcggtgaagt gatacgggta gcggaccggc ttcgccccgc cctggccgac
    10321 ggacaggtag ttgcgcagga acaggcggac cgccgtgccc tgttcgtcgt ggtcgaactc
    10381 gttgatcagc agcacgtccg ggtcgacccg ctggatggtc tcggcggcat tgcgcgcctg
    10441 ggcgttgtcc ggtgtggaca ggtcggtgat cagcgcgccc tgggcggagc ggttcaggga
    10501 ggcgttgaag gtggcgaacc gtacggtgcg ccggtgtccg ccggtcgcgg aggccgggaa
    10561 cgcggcggtg ccggccaggg ccgccccggc gagggaggcg agcgcgacgc ggcgggagaa
    10621 agatccggtg tggttcatcg gggctccggt gagggagggg acacgtgcac tgcgtgggtg
    10681 tggacgtcgg tagtctgcgc gcgtagagat gaacgccaca aggcccggcg agaactcccg
    10741 cattcacgct tgattcacgc gatggtgtga tcacgcaccg cccggaggat gcccgttcgg
    10801 ccccaggggt aggggcccgg ccatgacgca gcagcccttc gaactcccgc acttctacat
    10861 gccgtatccc gcgcggctga acccgcacgt cgacgaggca cgtgctcact cgaccgagtg
    10921 ggcgcgcgag atgggcatgc tggagggatc cgggatctgg gagcaggccg acctggacgc
    10981 gcacgactac ggcctgctct gcgcctatac ccaccccgac tgcgacggcc ccgccctctc
    11041 cctgatcacc gactggtacg tgtgggtctt cttcttcgac gaccacttcc tggagacctt
    11101 caagcgcacg caggaccggg tcggcggcaa ggcctacctg gaccggctgc cgctgttcat
    11161 gccgatggac ctgtcgacgc cgatgcccga gccggaaaac cccgtcgagg cgggcctcgc
    11221 cgacctgtgg gcgcgtacgg tgccctcgat gtcggtcgac tggcgccgcc gcttcgccgt
    11281 cgccaccgag catctcctga acgagtcgct gtgggagctg tccaacatca acgagggccg
    11341 ggtcgccaac ccggtcgagt acatcgagat gcgccgcaag gtgggcggcg ccccctggtc
    11401 gtcgggcctc gtcgagtacg cgaccgccga agtccccgtg tccgtcgccg ggtccaggcc
    11461 cctcagggtc ctcatggaga cgttctccga cggcgtgcac ctgcgcaacg acctgttctc
    11521 ctaccagcgc gaggtcgagg acgagggcga actcagcaac ggcgtcctgg tgttggagaa
    11581 gttcttcggc tgcaccaccc aggaggccgc cgacaccgtc aacgacgtcc tcacctcccg
    11641 gctccaccag ttcgagcaca ccgccctcac cgaagtcccc gccgtggccc tggagaaagg
    11701 cctcagcccc gaggaggtcg ccgcggtcgc cgcgtacacc caggggctgc aggactggca
    11761 gtccggcggg cacgagtggc acatgcgctc cagcaggtac atgaacgaac gcgccgaacc
    11821 caccgcgccc tggcggggcc cgaccgggcc cggcacctcc gccgccgacg tcggcgcgct
    11881 gctcgcggcg gccggcgccg aacgcctgcg cgcctacacc catgtgccgt tccagaaggt
    11941 cggcccgtcc cggctccccg acttccacat gcccttccag gtgcagctca gcccgcatct
    12001 gaacgacgcc cgccaccggc tgacccagtg gacgcaccgc atgggcatgc ttcaggaggg
    12061 cgtctgggac gaggacaaac tcgccgcgta cgatctcccg ctgtgctcgg ccggcctcga
    12121 cccggacgcc acccccgagg ccctcgacct cagctcgcag tggctcgcct ggggcactta
    12181 cggcgacgac tactaccccc tcgtcttcgg tcaccgccgc gacctggccg ccgcccggct
    12241 gaccacccgg cgcctgtcgg cctgcatgcc cctcgacggc gaggaggcga tcgtcccgct
    12301 caacggcatg gaacgcggac tcgccgacct gtgggcccgc acgacggccg agatgacccc
    12361 cgacggccgg cgcaccctga aggacgcggt cgacgtcatg accgagagct gggtgtggga
    12421 gctgtccaac cagctccaga accgcatccc cgacccggtc gactacctgg agatgcgccg
    12481 cgccaccttc ggctccgacc tcaccctgag cctgtgccgg atgggccacg gccccgcgat
    12541 cccgcccgag gtgtaccgca gcgggcccgt ccgctcactg gagaacgccg ccatcgacta
    12601 cgcctgcctc ctcaacgacg tcttctcgta ccagaaggag atcgagtacg agggcgagat
    12661 ccacaacgcg atcctcgtgg tccagaactt cttcggcatc gactacccgg ccgcgctcga
    12721 tgtcgtccac gacctgatga cccagcgcat gcagcagttc gagcacgtgg cggcgcacga
    12781 actgcccatc atgtacgacg acttcgggct ttcggacgag gcgcgcgaca tcatgcgcag
    12841 ctatgtggtc gacctccaga actggctggc cggcatcctg aactggcacc gggaggtcga
    12901 ccgctacaag gccgagtacc tggcccgccg cgcgcacggc ttcctgccgg accgcccgcc
    12961 ggcggtgccc gtcctcagct gacctcccgc atcgtccccg gggttcgcca gggtgtcccg
    13021 cagggccgcc agggccacgt gtgacgcgtc ttggcgcaga acgtaacagc cgtcgccggc
    13081 aacggacttc aatcctccgg atgcggtttt cgaaagtttt cggccggaac ggcacgttcc
    13141 tggaactcgg gcggtgcgcc gcgagtcttc cggggtgagg ggaacagaca acgagaacac
    13201 acgggggtgt tcgaccttga ccgacatcat cgagaggttc acggacagcg acagggagac
    13261 cggagcgcag gagcggccgc tcgacagcgg tgagctcacg ccgtacctgg ctccgctgcc
    13321 cgtccctccc gtcctgcggc ccgcgtccga cgacgtcctg cgggagaccg agatcgccct
    13381 gcgcccggcc tgggtgcgcc tgcacccgca gctgccgccg accctgatgt gggggtacga
    13441 cggccaggtg ccgggcccga ccatcgaggt gcggcgtgga cagcgcgtcc gcatcgcctg
    13501 gaccaaccgc attcccaagg acagcgagta cccggtcacc tcggtggagg tgccgctgcg
    13561 cagggacggc cgcccgcagg ccaccaccga gcccggccgt gcgggcgtcg agcccaacaa
    13621 ggacgtcgcc gccctgcccg cctggtcggt gacccatctg cacggcgcgc agacgggcgg
    13681 cggcaacgac ggctgggcgg acaacgcggt cggttacggc gacgcccagc tgtcggagta
    13741 tccgaacgac caccaggcgg tgcagtggtg gtaccacgac cacgccatga acatcacacg
    13801 ctggaacgtg atgacgggcc tgttcggcac ctacctcgtc cgtgacgacg aggaggacgc
    13861 cctccacctc cccggcggtg agcgggagat cccgctgctg ctggccgacc gcaacctcga
    13921 caccgacgag gacggccggc tcaacggccg gctgctgcac aagacggtga tcgtccagga
    13981 gaagaacccg gagaccggca agccggtctc cctcccgttc accggcccgt acaccacggt
    14041 caacggccgc atctggccgt acgccgaagt ggacgacgcc tggtaccgct tccggctggt
    14101 caacgcgtcc aacgcccgca tctacagcct cgtcctggtc gacgaggacg acaacccggt
    14161 cccgggcatc gtgcaccaga tcggcagcga cggcggactg ctgccgcgcc cggtgccgat
    14221 cgacttcgac ggcgcgatgc ccacgctgag cgcggcaccg gccgagcgct tcgacctgct
    14281 cgtcgacttc cgcggactcg cgggcaggac gctccgcctg gtcaacaagg gccgcaacca
    14341 gccgcccggc gtacccgacc cggcgggtga cgtgcgctac ccggcggtga tggagttccg
    14401 ggtccgggag acctgcgaga cggacacctt cgaactgccc gaggtgctct ccggctcctt
    14461 ccgccgcctc acgcacgaca tcgagcacgg ccaccggctg atcgtgctca ccccgcccgc
    14521 cacgaagggc gcgggcggtc acccggagat gtgggagatg gccgaggtcg aggacccggg
    14581 cgacatccag gtccccaccg agggcgtcat ccagatcacc ggcccgaacg gcaggaccag
    14641 gacttaccgg cgcacggccc ggaccttcaa cgacgccctc ggcttcacca tcgccgaggg
    14701 tagccacgag cagtggagct tcctcaacct cgcaccgatc gtccacccca tgcacatcca
    14761 cctggccgac ttccagctgc tgggccggga cgcctacgac gtctcgggct tcgacccggc
    14821 ggtgggcggt acccgcagcc cgatccggta cgacgcccgc acccggatcc cgctggcgcc
    14881 caacgagctc ggacacaagg acgtcttcca ggtgccgggg aaccagatgc tgcgcgtcat
    14941 gggcaggttc gacggcgcgt acggccggtt catgtaccac tgccacctcc tggagcacga
    15001 ggacatgggc atgatgcggc ccttcgtcgt catgcccgcg gaggcgttga agttcgacca
    15061 cggcggcgcc cacggcggcc acggggaggg acacaccggc tgaggtgagc ggtgcacgcg
    15121 cgtgtgacgt gtcaggcgtg cgtgggcacc ctgcgcgccg cgtgctcgac cgcggctcgc
    15181 gccagcgccc ggacgaccgg gtgcgggcgc gagccgtcgc cggacagctc cggctggaag
    15241 agcgaggcca ggaagaaggg atggccgggg agttcggcga tccggacgtg gccgtcctcg
    15301 tcgtgtccgg agaagcgcag cccgtgcgcg cgcagggtgt cgaggtgccg ggaggggccg
    15361 taggcgcaga agtaccgttc gacggtccgc tcggcaccca tcaccgactg ggcgagcgag
    15421 ccgggttcga tccggacagc cgcctcgtgg ccgaccaggg agcaggccag cggttcgatg
    15481 aggaagtcct cggcgtccgg gtcggtctcg gcgtgggcga cccgggtcag tccgcacaca
    15541 tgacgggcgt attcgaggag cgcgtgctgg aaaccgccgc acgtgccgag gaacgggatc
    15601 ccctcctcgc gcgccgtgcg gatcgcggac agcacacccg cctcactgtc gtacgggctg
    15661 cccggcagca cccacacggc gtcgaagcca cgcaccgcgt cgtcggccgc cgcgtcccgc
    15721 gacgggatcc agtaggcgtc gaggacgagc cggtcgcgtt cggcgagggc ctccagcagg
    15781 agcggcacgc gggtgtgcga ggcgacgttg ggggagcggt ccccgacgag ggcgagcctc
    15841 gccgtcttca ctgtccgagc agctgtgttc gtcatggacc tcatcctggg cgcgggccgc
    15901 acttcacgtc caacgatgat cggtgaacct ccgataagcg gagctgatgc cctgcgggat
    15961 gctgtccggc atggacccgc atctgctgcg cacctacgtc accgtcgccc gcctcgcctc
    16021 gttctccgac gccgcccgcg aactgggcta cacccagtcg gcggtgtccc agcagatcgc
    16081 cgcgctcgaa caggacctcg gcgcacccct gctcacccgc cgcccggtag cgcccacggc
    16141 ggccggtgac cggctcctcg aacacgcggg cccgctgctg ctgcgcctgg acgccgcccg
    16201 cgcggacgtc gtccgtatgg cggccgcccc cgagcacgga ctgacgctcg cgaccgcggc
    16261 gaccgcgctc gcaccacgcg tcctcgccgc gcttccgccc tccggcgtca ccctgcgtgt
    16321 gctgccgcgc gacgaggtcc ccgcggccgt cgccaccggc acggcggacc tcggcctcgt
    16381 cgacggcctg gccgccccca gcgacccgct gcgcctgccc gacgtggcgc cgctgaccac
    16441 gtacggcgtg ggcgaggaac cggtccgcgt gctcctgccc gacacgcacc cgctcgccca
    16501 ccgcacgggc ctgcgcctcg gcgacctggc cgacgcccgc tggctcgacg cccccgacgc
    16561 gggcctgccg ctcgcccagc tccgcgccgc gaacggcggc cagggtttcc gtcgtgccat
    16621 gcgctacgag ggcaccgacg tccgcaccct cacggccctg gccgcggcgg gacacgggct
    16681 gaccctcctg ccgtgctcgg cggccaccga ggtgcccggc acggtcgccg taccggtcgt
    16741 ggaaccgcgt gtcgtgcacc gcacggagct ggtgtacgcg ggggcgcccg ggggagcggc
    16801 ggcggtcgcg gaggcgttgg tgggacggct gtgagcgctc ccgcgaccga ggcgcccgcc
    16861 ggcctccccg acgtgccgtt ctccccgtga cgccgatggc ttcccgttcc tgaccaccgg
    16921 tcagtctcac tcgatcgtgg ctcgttgtgc gccggtgcgc agggtagtca ccagccggag
    16981 gcgatccgat ggaacacact gcgttgcgac ccaagcccat gccaggtcag ccgcccggcg
    17041 acggcgccag gaccgacccc ggcgcacgac gcccgcacac cgcgccccgc aggtgcggcc
    17101 gacggctcac ggccctgttg cccgccctgc tcgtggggct ggccctggtc ctgtccgggg
    17161 tcgggctcgg cacggtgggg gccacggtga tcggcatgag cagactcgcc gagctgcagc
    17221 gccagaccgg gccggacacc cccgcgaccc cggccccatc ggcacagccc ggctcctcgg
    17281 ccgcaccgtc cccgacgccg gcctcctcgc cggctcccgc cgccgcgacc ctcggcgtgg
    17341 aggccgtgga cgccgggaga ccgggcgccc tggtcgtcgg cctccatgtc ccgggcccgg
    17401 gatacacggc cggcctggtc cgcggcgacc tgatcctcgc gttcgaccgg acccgcgtcg
    17461 actcggccgc cgacctcgcg cgagccgtcg cggggacccg ccccggccgc gtggtcaccc
    17521 tgacggtgcg ccaccgcaac ggcggctacc agcaactgag ggcggtcccg ggcgtcgtca
    17581 cctgaccgcc tcacatccct gggggcggct tgggcgagta ccggaaaacc actggtcacc
    17641 ttccgccgcc ccgaccacga tgaccccatg ctgaccacac tcgtcgcctt tctcggagcc
    17701 tgcaccctcg tcgccgcctc gcccgggccg agcaccgtgc tgatcatcaa gcagtcgctg
    17761 cacagcagac gctccggctt cctgaccgtg ctcggcaacg agaccggcgt cttcatctgg
    17821 ggcatcgtcg ccgcgttcgg cctgaccgcc ctgctgacgg cgtccgaggt ggcgtacgac
    17881 gtgatgcgga tcgtcggcgc ggtcgtgctc gtcggcttcg gcatccaggc gctgcggcag
    17941 gcgcgccgca ccgagggagc ggagcaggac gcctggcagg gcgtccacaa gagcggctgg
    18001 gcctcctacc gcggcgggct gctgctcaac ctcgccaatc ccaaggcggc cgtcttcgcc
    18061 ctgtccttcc tcccgcagtt cgtaccggaa ggcgccccgc acctgccgac catgatcggc
    18121 ctcgccgcgc tctgggcggt ctacgaagtc ggctactacg gcctgtacgt ctggttcgtc
    18181 ggccgtatga aggccgtgct gtcccgcgcg ggcgtgcgcc ggcgcctgga acagatctcc
    18241 gggggcgtgc tgctgcttct cggcgtccgc atggcactgg agaactgaca ccgtgcccga
    18301 ccagccgccc gcgaaacccg ccgaccggct cgcgccgacc cctccgtccg ggcaggatgc
    18361 tgcccgtagt ccctatcagc gcccagggag gcccggatga ccggcaccgc acccgcgccc
    18421 ttcaccgccg acgactaccg ggcccgcatg gaacgggccg cgcggacggc cgcggacgcc
    18481 ggcctggccg gcctcctggt ggcacccggc cccgacctgg tgtggctcac cgggtacgcg
    18541 cccaccgccg agaccgaacg cctcaccctg ctggtcctcg tccccggcca ggaccccgtc
    18601 ctcgtcgtcc ccgccctgga ggcccccgac gccgcgaagg ccgccggcgc gcccggcctg
    18661 accctgcgcg actggaccga cggcaaggac ccctacgccg ccaccgccgc cctgctggag
    18721 gcgagcggcc ggttcggcat cagcgacaac gcctgggcga tgcacctgct ggccctgcaa
    18781 agggcgctgc ccggcgcctc ctacgcctcc ctcaccgacg ccctgccgat gctgcgggcg
    18841 gtcaaggacg ccgccgaact ggagctgatg gcggccgcgg gtgcggcagc ggacgccacc
    18901 ttcgaggaga tccggaaggt tccgttcggc ggacgccgcg agtccgaggt cgccgccgac
    18961 ctcgccgacc tccttcggca cttcggccac tcccaggtcg acttcaccat cgtcgcctcc
    19021 ggccccaacg gcgccaaccc gcaccacgag gtgggcgacc gcgtcatcga acgcggcgac
    19081 atggtcgtcc tcgacttcgg cggcctgaag gacggctacg gctccgacac ctcccgcacc
    19141 gtccatgtcg gcgaacccac cgacgaggag cgccgggtcc acgacctcgt acgcgaggcc
    19201 caggaggcgg gcttccgggc ggtacggccc ggcgtcgcct gccaggaggt cgaccgggcc
    19261 gcccgcgcgg tcatcgcgga cgccgggtac ggcgagtact tcatccaccg caccgggcac
    19321 ggcatcggcg tcaccacgca cgagccgccg tacatgatcg agggcgagga gcagcccctc
    19381 gtccccggca tgtgcttctc cgtggagccc ggcatctacc tgcccggccg gttcggcgtg
    19441 cgcatcgagg acatcgtgac ggtcaccgag gacggcggca ggcggctcaa cgacacgacc
    19501 cgcgagatgg tcatagtgga ctgaaccggc gaccgatccc ggagcaagga gcccccgtag
    19561 acccccgagc gacaacggcg cgaccatgac ccaggcaccg acacccaccg cggacaccgt
    19621 ccgccgactg gtccgttccc tgctcaagga gggcgtggac gactcggccg gacccgaggt
    19681 ccgccccgcc gccccgggcg ccgaccccgc cacgtggctg gtcggcaccc ggcatgtgct
    19741 gcgcctcgcc cccgaccgtg cggccgccgc ccgccaacgc cgggaactgc gccttcgcga
    19801 tctggtccgc ccgcacgtcc cggtcgcggt gccgacgagc gtcgcgcacg gcgagtgggc
    19861 gcccgggctg acctacaccc tggacaccaa ggtgcccggc gggtcgggcg gggagcacga
    19921 cgtgtccgcc gtcggcgagg ccgacctggc cgggctgctc acggggctgc gcgaggtccc
    19981 ggtacggcag gccgagacgc tcggcgtgcc gcgcgccgcc ccgcgctcgc tggaggccct
    20041 gcgccgcgcc gccgaaaccg ccgccgggcg cctcgccgcc gccgacgagt tcgacgccgc
    20101 ccgcctgcgc cagctcaccc agccggccgc cgtacagctc gcggcccagc ccaacacagc
    20161 ggtcctcgtc caccacgccc tcactggcga ccacctcgtc gtcagcgccg acggccgggt
    20221 gcgcggcgtc ctcggctggg ccgacacggt cctcggcgac cccgccgagg acatcgccgg
    20281 cctcgccctc gccgtcggct ccccggccgc cgtccgcgcc gccaccctcg ccggctacag
    20341 cgcccgcccg tgcctgcgcg gcctctggct cgcccgctgc gacgcggtcg tccgcctcgc
    20401 gaaccgcctc gacggcaagg gcgggacacc accgcaggtg ctgcgggcgc agctgcgcaa
    20461 cgcatgggag gcgatcctgc tggagcgggt cacggaactc agggacgacg aggcggacgg
    20521 ggagctgtag ggcgggcgga ccaggcggcg catacgcgga gcaggaggca cccccggcgg
    20581 acccgcccgc cctgcccgtt cacgcctgca acagcaccac acccgactcc ccgggcacat
    20641 gcagcacccc gtccgcaccc ggcgccgcca ccggctccca cgcggcgagc acctccgccc
    20701 gacgcggccc cagggggatc gccgccggct ccttggcgag gttgacggcc acgcgtacgt
    20761 cgccgcggcg gaaggcgagc cagcgctcgt gctcgtcgta ggccaccttg gtgtcggcca
    20821 ggtcggggtc ggtgaggtcg gggtgctcgt gacgcagcgc gatgagacgg cggtaccagg
    20881 ccagcacgcg cgcgtggggc tcgccggccg gctcggacca gtcgaggcag gagcgttccc
    20941 gggtcgccgg gtcctgcggg tcgggcacct cgtcctcggc ccagccgtgc gccgcgaact
    21001 cccgccgcct gccccgccgt accgcctcgg cgagctccgg atcggtgtgg tcggtgaaga
    21061 actgccaggg tgtgcccgcg gcccactcct cgcccatgaa cagcatgggt gtgaacggcg
    21121 cggtcagcgt cagcgtcgcc gcgcaggcca gcaggccggg ggagagcagg gccgcgagcc
    21181 ggtcgccctg ggcccggttg ccgacctggt cgtgggtctg gctgtagccg aggaggcggt
    21241 gcgcggccac gcgcgcccgg tccaggcggc gcccgtggct gcggccccgg aagctggagt
    21301 aggtgccgtc gtggaagtag ccgccggtga gggtcttggc gagggccgcc atgggcgccc
    21361 gggcgaagtc ggcgtagtag ccctgggact cgccggtcag cgcggtgtgc acggcgtggt
    21421 ggaagtcgtc gttccactgc gcgtgcagac cgaggccgcc ctcctcgcgc gcggtgatga
    21481 gccgggggtc gttcaggtcg gactccgcga tcaggaacag cggccggccc aggccggcgg
    21541 cgagggcgtc gacggccgtc gacagctcct ccaggaagtg gcacgcgcgc gtgtccacca
    21601 gcgcgtgcac cgcgtccagc cgcaacccgt cgagccggta gtcccgcagc caggccagcg
    21661 cgctctgcac gagatacgcg cgcacctcgt ccgagccggg cgcgtccagg ttgacggcgg
    21721 cgccccaggg cgtctggtgg gtgtccgtga ggtagggccc gaaggcgggc agatggttcc
    21781 cggacgggcc gaagtggttg tgcacgacgt cgaggaccac gcccaggccc agttcatggg
    21841 cccggtcgac gaagcgtttc agcgcctcgg gcccgccgta cggctcgtgc acggcccaca
    21901 gcgacacccc ctcgtacccc cagccgtgcc gcccggggaa ggggctcagc ggcatcaact
    21961 cgacatgggt gacgccgagt tcggcgagat ggccgaggcg ctcggctgcc gcgtccagcg
    22021 tgccctcgcg cgtgtacgtg cccacatgga gctcgtacag caccgcgccc ggcagcggcc
    22081 gcccggccca ctcgccgcgc caggcgtacc gcccgtggtc gacgaccgcg ctcagcccgt
    22141 ccgggccgtc cggctggcgg cgcgagcgcg ggtcgggcag cacggggccg tcgtcgagcg
    22201 cgaagccgta ccgggttccg tcccgcgcct ccgcctcccc ccaccaccat cccgcgcgat
    22261 cgggatcgcg ctccaacgcg cgcgtggtgc cctcgcaatg gagggtcact cggtcggcct
    22321 gcggtgccca cacctcgaac tgcacggacg gttccccttc gtctgctcac cgtgatgtag
    22381 cccgtccatg gtgcttcaaa cgagatcaat ccgcttttga atcttccctt ttgcggcagg
    22441 tgtcgcggcc ggtggcgtcg atcacgcacg cgtggcggcc gtttccgcgt tttctggaca
    22501 ccgggggttc actgcccgac aatcagcacc gtgacgtcgt ctttcgagtt caatacctac
    22561 cccgcgcggc tctccgacgt ggagcgcgac aaggtgctga aggtgctccg tgacggcgtc
    22621 gccatgggcc ggctgtcgca cgacaccttc gtacggcgca tggaactggc cctcgccgcc
    22681 cgccgtgtgg acgagctcgc cgtgctcacc gccgacctgc cctccgagag ccgcctgtcg
    22741 cgtctggtgt tcggcaccgt cgaggcggtc tccggcttca cggtacggct gcgcagggcc
    22801 tggcaggccg agcggctgcc caagctgctg ctgccccacc ccgcggccgg tcatccgctg
    22861 cggatcggcc gcgaccccgc caacggactg cggctgaccc acgagacggt gtcccgggtg
    22921 cacgcggaac tgagccacca ggccggcata tgggtgctgc gcgacctcgg ctccaccaac
    22981 gg
//
