LOCUS       NZ_KQ947987            11365 bp    DNA     linear   CON 21-APR-2024
DEFINITION  Streptomyces curacoi strain DSM 40107 PRJNA299217_s004, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ947987
VERSION     NZ_KQ947987.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces curacoi
  ORGANISM  Streptomyces curacoi
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 770615)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Draft genome sequence of Streptomyces curacoi DSM 40107, type strain
            for the species Streptomyces curacoi
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 770615)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-OCT-2015) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 13-OCT-2014
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 65.7x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001513975.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 02:05:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,531
            CDSs (total)                      :: 7,455
            Genes (coding)                    :: 7,251
            CDSs (with protein)               :: 7,251
            Genes (RNA)                       :: 76
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 204
            CDSs (without protein)            :: 204
            Pseudo Genes (ambiguous residues) :: 0 of 204
            Pseudo Genes (frameshifted)       :: 91 of 204
            Pseudo Genes (incomplete)         :: 154 of 204
            Pseudo Genes (internal stop)      :: 21 of 204
            Pseudo Genes (multiple problems)  :: 54 of 204
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:06:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 329990
            Orig. end                         :: 341355
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ947987.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..11365
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="4"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11365
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11365
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6365](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..6365)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    210..219
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     gene            507..1238
                     /gene="hemQ"
                     /locus_tag="AQI70_RS14945"
                     /old_locus_tag="AQI70_14935"
     CDS             507..1238
                     /EC_number="1.3.98.5"
                     /codon_start=1
                     /gene="hemQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018564417.1"
                     /locus_tag="AQI70_RS14945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_14935"
                     /product="hydrogen peroxide-dependent heme synthase"
                     /protein_id="WP_062149066.1"
                     /transl_table=11
                     /translation="MSDDAPTTESGRIPNKGKLAKDLNEVIRYTLWSVFKLKDVLPEDR
                     AGYADEVQELFDQLAAKDVTIRGTYDVSGLRADADLMIWWHAETSDQLQEAYNLFRRTK
                     LGRALTPVWSNMALHRPAEFNRSHIPAFLADETPRNYVSVYPFVRSYDWYLLPDEDRRR
                     MLADHGKMARGFPDVRANTVASFSLGDYEWLLAFEADELYRIVDLMRHLRASEARMHVR
                     EEVPFFTGRRKSVAELVAGLA"
     gene            complement(1239..2906)
                     /locus_tag="AQI70_RS14950"
                     /old_locus_tag="AQI70_14940"
     CDS             complement(1239..2906)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (109-483). E-value:
                     4.5e-21. Score: 67.5. Matches aSDomain:
                     nrpspksdomains_AQI70_RS14950_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997029.1"
                     /locus_tag="AQI70_RS14950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_14940"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_062149069.1"
                     /sec_met_domain="PF00561 (E-value: 5.7e-25, bitscore: 83.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAPALYSAVGVLLLTALSAAPAGSTGAAPGTAELHGTAVAAARA
                     RAAGIDFGKCPKEQDMPAALQCGKVSVPLDYAHPNGKQIELTVSRVRATHKDPHNSKRR
                     VPRKGALVYNPGGPGASGMYFPLIGVMPAWKRLAAAYDLVGYAPRGVERSAPLSCQEPK
                     QVFKGPLLAPTHPSESHKKERIARAKAYARGCAQRAGSALRHYNSLNNARDLDVLRAAL
                     GEEKLTFMGASYGTYFGALYATLFPSHVRRMVFDSAVNPDPAMVWYRNNLAQSAAFEGR
                     WADFREWVAEHHKVYGLGDTAEEVLRSYEKVRARLAAEPAGGKVGQEQLQETFLQAGYY
                     DDYWPSRARALSAYLKGDSKPLVELAAPATEAAAEEENSDAVYTAVECNDAPWPTDWDV
                     WDRDNTRLARVAPFETWDNVWMNLPCAYWQAPRQEPLDVRTGPGEVPPLLILAAERDAA
                     TPYDGALEMHRRLSGSVLVTERDAGTHGIAYGPNACVNGYVDAYLLEGRLPARRAACEG
                     HPEPKPERPDDRTDKKRGAHPGTAPGDRPRTAAARLPH"
     aSDomain        complement(1458..2579)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQI70_RS14950_Abhydrolase_1.1"
                     /evalue="4.50E-21"
                     /label="AQI70_RS14950_Abhydrolase_1.1"
                     /locus_tag="AQI70_RS14950"
                     /protein_end="483"
                     /protein_start="109"
                     /score="67.5"
                     /tool="antismash"
                     /translation="ALVYNPGGPGASGMYFPLIGVMPAWKRLAAAYDLVGYAPRGVERS
                     APLSCQEPKQVFKGPLLAPTHPSESHKKERIARAKAYARGCAQRAGSALRHYNSLNNAR
                     DLDVLRAALGEEKLTFMGASYGTYFGALYATLFPSHVRRMVFDSAVNPDPAMVWYRNNL
                     AQSAAFEGRWADFREWVAEHHKVYGLGDTAEEVLRSYEKVRARLAAEPAGGKVGQEQLQ
                     ETFLQAGYYDDYWPSRARALSAYLKGDSKPLVELAAPATEAAAEEENSDAVYTAVECND
                     APWPTDWDVWDRDNTRLARVAPFETWDNVWMNLPCAYWQAPRQEPLDVRTGPGEVPPLL
                     ILAAERDAATPYDGALEMHRRLSGSVLVTERDAG"
     gene            complement(3030..3827)
                     /locus_tag="AQI70_RS14955"
                     /old_locus_tag="AQI70_14945"
     CDS             complement(3030..3827)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997028.1"
                     /locus_tag="AQI70_RS14955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_14945"
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_062149072.1"
                     /transl_table=11
                     /translation="MFWVLLLLLAWAVAGTACTRLCLAAVHAAAMDTKEAAAGRGHDLT
                     LYEAAFLSGGPRRVADLTLVSMARQRRLLLAHTGWATVVDPRGRDEMERSVIGAIGPEG
                     QSRIEPVRDAAAAADAVGSLADRLVSAGLAVPDGMRSGVAAAIGRVRLAAAVVLALGVI
                     ALLTPAQSDMPAHLVALWFALPFVLTLSCLAIARIEIHPYTQWASPAGQRLLSALVRRS
                     GGGDDRRYLTSVAVRGVRAIGEPELRAAFAHREPPPEVTPWRG"
     misc_feature    complement(3834..3847)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.84"
                     /tool="antismash"
     misc_feature    3897..3911
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.38"
                     /tool="antismash"
     gene            complement(3930..4718)
                     /locus_tag="AQI70_RS14960"
                     /old_locus_tag="AQI70_14950"
     CDS             complement(3930..4718)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997027.1"
                     /locus_tag="AQI70_RS14960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_14950"
                     /product="DUF4142 domain-containing protein"
                     /protein_id="WP_062149075.1"
                     /transl_table=11
                     /translation="MRPRPPINGRGIFSGTGIIITGLTATLLAMIFPIWSYEDRSGTGL
                     DVLNAETVPTGYGPLSGLDREFLTKVRLAGLWELPAGRQAQQKGTTEAVRTAGQHLVEG
                     HMFLDERVRDVAAKLRMELPNEPTEQQREWLATLDSAQGVEYERQFANILRLAHGKVFS
                     VVAQVRASTRNSLVRKLADDANSTVLDHITVLEATGYVDFDAVARDMVADSTPPLTPPP
                     APPGPAVDPAPAVPVSPPPSPTYSLPPAATSPRPKDAAGF"
     misc_feature    complement(4722..4738)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.35"
                     /tool="antismash"
     misc_feature    4768..4784
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.02"
                     /tool="antismash"
     gene            complement(5001..6365)
                     /locus_tag="AQI70_RS14965"
                     /old_locus_tag="AQI70_14955"
     CDS             complement(5001..6365)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997026.1"
                     /locus_tag="AQI70_RS14965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_14955"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_208607365.1"
                     /sec_met_domain="DUF692 (E-value: 9.2e-98, bitscore: 322.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVRLGTGIGWRPEIAEAVENMPGIEWVEAVAENVCPGHLPESLVR
                     LRERGVTVVPHGVSLGLGGAERPDAGRLAALAERVTALGSPLVTEHIAFVRAGGPLTAS
                     PRLEAGHLLPVPRTRDALDVLCENVRIAQDALPVPLAVENIAALISWPGEEMTEGQFLY
                     ELADRTGVRLLIDVANLHTNQVNRGEDAAKALAELPLEAIAYVHVAGGFERDGVWHDSH
                     AHPVPQPVLDILTDLASRVSPPGVLLERDENFPERAELERELGAIRGALEKGSAERRAS
                     ATEASAAASPEGASRGARERETVREQGAAGVEGLTDPARQRLGLAQAALLSALVAGTPV
                     PEGFDRVRLGVQARALAGKRADVVAKVAPELPVILGDGYRGAFLAYAHGHPMSDGYRRD
                     ALDFAGYLLAEGRLEDALVRAELREWWLERSGPKPRSGRPGVRLARATRRVLLRR"
     gene            complement(6561..7292)
                     /locus_tag="AQI70_RS14970"
                     /old_locus_tag="AQI70_14960"
     CDS             complement(6561..7292)
                     /EC_number="3.1.1.29"
                     /GO_function="GO:0004045 - aminoacyl-tRNA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997025.1"
                     /locus_tag="AQI70_RS14970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_14960"
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="WP_062149078.1"
                     /transl_table=11
                     /translation="MTSDPTVPGDSPFRTEPSTRDGAPQFVLPLVVRIERAAPPARTDA
                     LETAARAVLVMLSDERSIGDGEWAQAVRDWQDARIRKVVRRARGAEWHRAEALPGITVT
                     GKSAEVRVFPPVPLDGWPKDLARLQVSGTDLDDPEPPAEADSSAPVLWLNPDVDMSAGK
                     AMAQAGHGAQLAWWELSEEEKAAWRDAGFPLAVRTAAPGRWGELTGSGLPLVRDAGFTE
                     IAPGSCTVVADHPALRQTPRV"
     gene            7381..8259
                     /locus_tag="AQI70_RS14975"
                     /old_locus_tag="AQI70_14965"
     CDS             7381..8259
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997024.1"
                     /locus_tag="AQI70_RS14975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_14965"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_062149081.1"
                     /transl_table=11
                     /translation="MQRDLRLHNVGRRYGLRGPWVLRGVHLTVPPGTLIRVEGANGTGK
                     STLLRLLARLDAPSEGRITGRPRTAYVPERFPTALPFTALGYLTHLGTVHGLSRPAATR
                     AAHEHLDRFGATAHARTPMAQLSKGSSQKVAVAQALLADPELLVLDEAWTGLDAAARAE
                     LERAVAERTAAGTAVVFVDHDPRRLAGAPDATYTVHAGGLDRRTGQESAPPTGPHTTVV
                     VQGPRGAGLPAEATRIATRTDEPTPGIHRLTVPASHSDIVLRALLTARPPWHVVSVSQE
                     TPDPSEAESRR"
     misc_feature    7444..7446
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8256..8927
                     /locus_tag="AQI70_RS14980"
                     /old_locus_tag="AQI70_14970"
     CDS             8256..8927
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997023.1"
                     /locus_tag="AQI70_RS14980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_14970"
                     /product="hypothetical protein"
                     /protein_id="WP_062149084.1"
                     /transl_table=11
                     /translation="MTALLCYQAALLLRSQRWLPPFILYAVFLAVGVQGGQPILDSLGY
                     AAAALLPVAAWLVRICVTNEPPAARSCVSAAVGPGRAHLAALLVALGAAAMLGTVTIVV
                     VTLVSDPASADHQTRVPRLPAGAAGLLAALACALLGTAVGALTTWPLLRSTGRAVPAML
                     LAALLSVVVTGSPAQAAVSGLVTGSRSGTVPLPVLPLAAAALLTAAAIAAACALTSRRS
                     P"
     gene            complement(8919..9110)
                     /locus_tag="AQI70_RS14985"
                     /old_locus_tag="AQI70_14975"
     CDS             complement(8919..9110)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125244.1"
                     /locus_tag="AQI70_RS14985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_14975"
                     /product="hypothetical protein"
                     /protein_id="WP_062149087.1"
                     /transl_table=11
                     /translation="MSEEQPMTDYCLIDATRPPRADGPPYAECVLCREPTEYPESYKGI
                     TLCPVCEWQEAQRTACSG"
     gene            complement(9129..9995)
                     /locus_tag="AQI70_RS14990"
                     /old_locus_tag="AQI70_14980"
     CDS             complement(9129..9995)
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003997021.1"
                     /locus_tag="AQI70_RS14990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_14980"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_062149090.1"
                     /transl_table=11
                     /translation="MITLVRRVTAAACALGAALGALAGCTAPEATRAPHPAPSASAASP
                     VSPAAEPPTLAPGPAGLTPVFEHGPRARDKTVALTFDADMTADQGTRAARGERFDNPGL
                     VAALRELKVPATVFMTGRWAEEYPVQARAIGRHPLFEVANHSYSHYAFTDDCYGLPTLD
                     EERMRADVERAYAVFRKVGVRDPMPYFRFPGGCYDRRALKALTPVGVTAVQWDVVSGDA
                     FATDADAVAREVLDGVRPGSVVVLHCTLSAAPTTERAVRTIVPALRAKGFRFVKVSELI
                     GAASSRL"
     gene            complement(10087..11010)
                     /locus_tag="AQI70_RS14995"
                     /old_locus_tag="AQI70_14985"
     CDS             complement(10087..11010)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AQI70_RS14995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AQI70_14985"
                     /product="hypothetical protein"
                     /protein_id="WP_063801589.1"
                     /transl_table=11
                     /translation="MSASRGRSFPATGELLQHLLATKPRYQRLWLGKTGRVRGGLSQSA
                     VARVITLHLWESGERSESETSLQRTLKDRVSRALNGTAISAETLKWIINAFDMDSGDTD
                     HLWATYAAELGSTPGIAHTLRRRRKMASRQRHRTVSLVERYFLDESGALKLRNTFHTIR
                     AIEDGVDLYMFNHEPQASDIEVLHGGTPGLQHVYGGGMVGREIILTPPLLKSQTTALEY
                     RTHFVQEPAFPATEVRRAAFARTEHVDLAVVFPAKRTPRVVWWCVWDDHLGGVPVQRKE
                     MTPQNGTVRHYVPFIEETSVGFAWKW"
     misc_feature    complement(10639..10641)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    11111..11126
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.76"
                     /tool="antismash"
ORIGIN
        1 accgacctgc ccgcgggcag cggcttcctc gtaccgccgg tcgacggacg caccatcaag
       61 gcgtcgacgt tcgcctccca gaagtggggc tggatcgccg acgagaaccc ggacgtggtc
      121 gtgctgcgca cgtccgtggg gcggtacggc gagacgcgga tcctggagcg tgacgacgcc
      181 cacctcgtcg acgtctcccg gcacgacctg aaggcggcca ccggcctcga cgccaccccc
      241 ctcgaaaccc gcgtcacccg ctggaccgac ggcctgcccc agtacccggt cggccaccac
      301 gcgcgcgtgg cccgcgtccg cgagcacatc gccgggctgc ccggcctcgc cgtgtgcggc
      361 gcgcagtacg acggcgtggg catcccggcg tgcatcgcga gcgcgtatgc cgcggtggac
      421 cagctggacg gagacctgag cggtgtggag gagctcaccg cccacccggt gcagagtctg
      481 cacggaggag caggagaata agggacatga gtgacgacgc ccccaccacc gagtccggca
      541 ggatcccgaa caagggcaag ctggccaagg acctcaacga ggtcatccgc tacaccctct
      601 ggtcggtctt caagctgaag gacgtgctcc ccgaggaccg cgcgggctac gccgacgagg
      661 tccaggagct gttcgaccag ctcgccgcca aggacgtgac gatccgcggc acgtacgacg
      721 tgtccgggct gcgcgccgac gccgatctca tgatctggtg gcacgccgag accagcgacc
      781 agctgcagga ggcgtacaac ctcttccgcc gcaccaagct gggccgcgcc ctcacgccgg
      841 tctggtcgaa catggcgctg caccgccccg ccgagttcaa ccgctcgcac atcccggcgt
      901 tcctcgccga cgagacgccg cgcaactacg tcagcgtcta ccccttcgtg cgctcctacg
      961 actggtacct cctgcccgac gaggaccgcc gccgtatgct cgccgaccac ggcaagatgg
     1021 cccgcggctt cccggacgtc cgcgccaaca cggtcgcctc gttctcgctg ggcgactacg
     1081 agtggctcct cgccttcgag gccgacgagc tctaccgcat cgtcgacctc atgcgtcacc
     1141 tgcgggcttc ggaggcgcgg atgcacgtgc gcgaagaggt gccgttcttc acggggcgcc
     1201 gcaagagcgt cgccgagctg gtcgcgggcc tcgcctgatc agtgcgggag ccgggcggcg
     1261 gccgtccggg gccggtcgcc cggtgccgtc ccggggtggg cgccccgctt cttgtccgtg
     1321 cggtcgtccg ggcgctccgg cttcggctcg gggtgcccct cgcacgccgc gcgccgtgcc
     1381 gggaggcggc cctccagcag atacgcgtcg acgtagccgt tgacgcaggc gttcgggccg
     1441 taggcgatgc cgtgcgtgcc ggcgtcccgt tcggtcacca gcaccgaacc cgacaggcgc
     1501 cggtgcatct ccagggcccc gtcgtacggc gtggcggcat cccgctcggc ggccaggatc
     1561 agcagcggcg gcacctcgcc cggcccggtc cgcacatcga ggggctcctg ccggggcgcc
     1621 tgccagtagg cacacggcag gttcatccac acgttgtccc aggtctcgaa cggcgccacc
     1681 cgggcgagcc gcgtgttgtc ccggtcccac acgtcccagt ccgtcggcca gggcgcgtca
     1741 ttgcactcca cggccgtgta gaccgcgtcc gagttctcct cctcggccgc cgcctccgtc
     1801 gccggcgcgg ccagctcgac caggggcttg gagtcgccct tcagatacgc cgacagcgcc
     1861 cgcgcgcgcg acggccagta gtcgtcgtag taaccggcct gcaggaacgt ctcctgcaac
     1921 tgctcctgcc cgaccttccc gcccgccggc tcggcggcca gccgcgcacg caccttctcg
     1981 tagctgcgca gcacctcctc ggcggtgtca cccagcccgt acaccttgtg gtgctcggcg
     2041 acccactccc ggaagtcggc ccaccgcccc tcgaacgcgg ccgactgggc gaggttgttg
     2101 cggtaccaga ccatcgcggg gtccgggttc accgcagagt cgaacaccat ccgccgcacg
     2161 tgtgagggga agagggtcgc gtacagggcg ccgaagtagg tgccgtacga cgcgcccatg
     2221 aaggtcagct tctcctcgcc cagcgcggcg cgcaggacgt ccaggtcacg ggcgttgttg
     2281 agggagttgt agtggcgcag cgcgctgccc gcgcgctggg cgcagccccg ggcgtaggcc
     2341 ttcgcccggg cgatgcgctc cttcttgtgc gactccgagg ggtgcgtcgg cgccagcaag
     2401 ggccccttga agacctgctt gggctcctgg caggacagcg gcgcggaacg ctcaaccccg
     2461 cgcggggcgt agccgaccag gtcgtacgcc gccgccagcc gcttccacgc gggcatgacg
     2521 ccgatcagcg ggaagtacat gccggaggcg cccggtccgc ccgggttgta gaccagggcg
     2581 cccttccgtg gcacccggcg cttgctgttg tgcgggtcct tgtgcgtggc ccggacccgg
     2641 ctgacggtga gttcgatctg cttgccgttg gggtgcgcgt agtcgagcgg gacggacacc
     2701 ttgccgcact gcagggcggc cggcatgtcc tgctccttgg ggcacttgcc gaagtcgatg
     2761 ccggccgccc gggcgcgggc ggcggccacc gcggtgccgt gcagctcggc tgtgcccggg
     2821 gcggccccgg tgctgccggc cggggcggcg ctgagggctg tcaggagcag gacccccacg
     2881 gccgagtaga gggcgggagc tctcatcgcg tatcccttcg gtgcacggca gcaacaaaag
     2941 ggatatttcg tccgtctgtt gacgaaggca agcaccaccc tgccggtgtc ggcgtcaatg
     3001 ccccctatgc gccaccgggc gcccggcggt cagccgcgcc agggcgtcac ctcggggggc
     3061 ggctcgcggt gcgcgaaggc cgcgcgcagc tccggctcgc cgatcgcgcg tacgccccgt
     3121 acggccacgg aggtgagata ccggcggtcg tccccgccgc cggagcgccg gaccagggcg
     3181 ctcaacagcc gctgcccggc tggggaggcc cactgggtgt aggggtggat ctcgatccgg
     3241 gcgatggcga ggcagctcag ggtgagcacg aaggggagcg cgaaccagag tgcgaccaga
     3301 tgcgcgggca tgtccgactg agcgggcgtc agcagggcga tcacccccag cgccagtacg
     3361 accgccgcgg cgagccgcac ccgcccgatc gcggccgcga ccccgctgcg catcccgtcg
     3421 ggtacggcca ggcccgcgct gaccaaccgg tccgcgaggc tgcccaccgc gtcggcggcg
     3481 gccgcggcgt cccgtaccgg ctcgatccgg gactgaccct ccgggccgat ggctcctatc
     3541 accgagcgct ccatctcgtc ccgcccgcgc ggatcgacga ccgtcgccca gccggtgtgc
     3601 gcgagcagca gccgccgctg ccgcgccatg gagacgaggg tcagatcggc gacccggcgg
     3661 gggccgccgg acaggaacgc ggcctcgtac agcgtcagat cgtgtccccg gcccgcggcc
     3721 gcctctttcg tgtccatggc cgcggcgtgt acggcggcca ggcacagccg tgtacacgcc
     3781 gtgccggcaa cggcccacgc cagcagcaga agaaggaccc agaacatgcc gcgtttctat
     3841 gccaaatgct ccccgaaaca ccatgccttg ttcaccatac ggaccgagag ttgccgggat
     3901 gtgacgttcc ggatcgggga gttcgggcct cagaaccccg cggcgtcctt cgggcgcggg
     3961 ctggttgcgg ccggcggcag tgagtaggtc ggcgagggag gcgggctcac cgggacggcc
     4021 ggagcggggt cgacggccgg gccgggcggg gcggggggcg gggtgagcgg aggcgtgctg
     4081 tcggcgacca tgtcccgggc cacggcgtcg aagtcgacgt aaccggtggc ctcgaggacc
     4141 gtgatgtggt ccagcaccgt gctgttggcg tcgtcggcga gcttgcggac gagggagttg
     4201 cgggtgctgg cccgcacctg ggcgacgacg gagaacacct tgccgtgcgc cagccgcagg
     4261 atgttggcga actgacgctc gtactcgacg ccttgggccg agtccagggt cgccagccac
     4321 tcccgctgct gctcggtcgg ctcgttgggc agctccatgc ggagcttggc ggcgacgtca
     4381 cgcacccgct cgtccaggaa catgtgcccc tcgacgagat gctgacccgc ggtccgtacg
     4441 gcctcggtgg tccccttctg ctgcgcctgc cggccggcgg gcagctccca gagcccggcc
     4501 agccggacct tggtgaggaa ctcgcggtcg agaccggaca gcgggccgta cccggtcggg
     4561 acggtctcgg cgttgagcac gtccagaccg gtcccggacc ggtcctcgta cgaccagatc
     4621 gggaagatca tcgccagcag cgtcgccgtc aggccggtga tgatgatccc ggtgccgctg
     4681 aagatgcctc ggccgttgat ggggggtcgc ggtcgcatgg gtgcctcctg ttgcggcacc
     4741 gcacgttagt gcgcttcgag ggttgggttg gcatattact tcgggtgcgc cggggtctac
     4801 gccaactgcc gtacgggagc gaatggttgc aacgagggtg gatacgggcg aatggggagg
     4861 gggagggtct gacgttcagg ggcaaaggcg ggcgaatcga ctgctcagac cgcgctgcgc
     4921 ggctggggtg ttaacccagg cacactcgcg gggcgggagc gctcagcggc tgaacggcac
     4981 tgggcgcacg cggggtgcgc tcaccggcgc aggaggaccc ggcgcgtggc ccgggccagc
     5041 cgcacccccg gccgccccga gcgtggcttc ggccccgacc gctccagcca ccactcccgc
     5101 aactccgccc ggaccaaggc gtcctccagg cgcccctcgg ccagcagata cccggcgaag
     5161 tccagcgcgt cgcgccgata gccgtcgctc atcgggtgcc cgtgcgcgta cgcgaggaag
     5221 gccccccggt acccgtcccc gagtatcacc ggcagctccg gcgccacctt ggccacgacg
     5281 tccgcccgct tcccggcgag cgcccgcgcc tgcacaccga gccgcacccg gtcgaaccct
     5341 tccggcaccg gcgtcccggc gacgagcgcg gacagcagcg cggcctgcgc gaggccgagg
     5401 cgctgacggg cggggtcggt gagcccctcc actccggccg ccccctgctc ccgtacggtc
     5461 tcccgctccc gagccccccg agaggcgcct tccggggacg ccgctgcgga cgcttccgtg
     5521 gcggacgccc tccgctcggc ggaccccttc tccaacgcgc ctcgaatcgc ccccaactcc
     5581 cgctccagct ccgcccgctc ggggaagttc tcgtccctct ccagcaggac ccccggcggg
     5641 gacacccggg acgccaggtc ggtcaggatg tccaggaccg gctgcgggac cgggtgggcg
     5701 tggctgtcgt gccagacgcc gtcgcgctcg aagccgcccg cgacatggac gtacgcgatg
     5761 gcctccagcg gcagttcggc gagtgccttg gccgcgtcct cgccccggtt gacctggttg
     5821 gtgtgcaggt tggcgacatc gatgagcagc cgcacccccg tgcggtcggc gagctcgtac
     5881 aggaactgcc cctcggtcat ctcctcgccc ggccaggaga tgagcgcggc gatgttctcc
     5941 acggcgagcg gcacgggcag cgcgtcctgc gcgatgcgga cgttctcgca cagcacgtcc
     6001 agggcgtccc gggtgcgcgg cacgggcagc agatgccccg cctccagccg cggggacgcc
     6061 gtcagcggcc cgcccgcgcg tacgaacgcg atgtgctcgg tgaccagcgg cgaccccagc
     6121 gccgtaaccc gctccgcgag agcggccagc ctcccggcgt cggggcgctc cgcgccgccc
     6181 aggccgagcg agacgccgtg cgggaccacg gtcaccccgc gctcccgcag ccgtaccagc
     6241 gactcgggca gatggcccgg gcagacgttc tcggcgacgg cctcgaccca ctcgatgccc
     6301 ggcatgttct ccacggcctc cgcgatctcc ggacgccacc cgatccccgt gcccagtcgc
     6361 accatcgtcc cctcctcggc ctcttccgta cccgctgtcc cgtctcctcg gacgtgtcgg
     6421 acgtgacggg ggtatggccc cgcgggcccc gcccgaaccc ctgggcggac accttcagag
     6481 caacatttga ggttgggaac cgcgccccgc acaccgtgaa cggccgccgt aaggtcgtac
     6541 gcgcgggagg ccggggatgt tcagacgcgg ggcgtctgcc gcagcgcggg atggtcggcg
     6601 acgacggtgc acgacccggg agcgatctcg gtgaacccgg cgtcacgcac caacggcagc
     6661 ccgctgccgg tgagttcacc ccagcgcccc ggggccgcgg tccgcacggc gagcgggaaa
     6721 ccggcgtcgc gccaggcggc cttctcctcc tccgacagct cccaccaggc cagctgtgcc
     6781 ccgtgccccg cctgcgccat cgccttgccg gccgacatgt cgacatccgg gttcagccag
     6841 agcacgggcg ccgacgagtc ggcttccgcg ggcggctccg gatcgtcgag gtcggtaccg
     6901 gacacctgga gccgggcgag atccttgggc cacccgtcca ggggcacggg cggaaacacc
     6961 cgtacctccg ccgacttgcc ggtgaccgtg atccccggca gtgcctccgc ccggtgccac
     7021 tcggctcccc gagcccgccg tacgaccttg cggatacggg cgtcctgcca gtcccggacg
     7081 gcctgggccc attccccgtc accgatggac cgctcgtcgc tcagcatgac cagcaccgca
     7141 cgggcggcgg tctccagggc gtccgtacgg gccggcggag cggcccgctc gatgcggacg
     7201 acgagcggca ggacgaactg gggtgccccg tcgcgcgtcg agggctcggt acgaaagggg
     7261 ctgtcgccgg gaacggtcgg atcactggtc acgtcctcca gtctgccagg cacaagatcc
     7321 ctctcacggc gggatccgtc tcacggcggg atccgtctca cggcgggaga ggatgggccc
     7381 atgcaacgcg atcttcgtct gcacaacgtg ggccgccgct acggcctgcg cgggccctgg
     7441 gtgttacgcg gcgtccacct caccgtgccg ccgggcacgc tgatccgcgt ggaaggcgcc
     7501 aacggcaccg gcaaatccac cctgctccgc ctcctcgccc gcttggacgc cccctcggaa
     7561 ggccgcatca ccggccgccc ccgcaccgcg tacgttcccg aacgtttccc caccgccctg
     7621 cccttcaccg ccctcggcta cctgacccac ctcggcacgg tccacggcct gtcccggccg
     7681 gcggccaccc gagccgccca cgagcacctg gaccgtttcg gcgccaccgc ccacgcccgt
     7741 accccgatgg cccagctgtc gaagggcagc agccagaagg tcgccgtcgc gcaggccctg
     7801 ctcgccgacc cggagctgct cgtcctcgac gaggcgtgga ccggcctgga cgccgccgcc
     7861 cgcgccgaac tggaacgtgc cgtcgccgaa cgcaccgccg ccggcaccgc ggtggtcttc
     7921 gtcgaccacg acccgcgccg cctcgcgggg gcgcccgacg cgacgtacac cgtgcacgcc
     7981 ggcggcctcg accgccggac cgggcaggag agcgcgccgc ccaccggccc gcacacgacc
     8041 gtcgtcgtcc agggaccgcg cggcgcgggc ctgcccgccg aggcgacccg catcgcgacg
     8101 agaacggacg aacccacccc cggcatccac cggctgaccg tccccgcctc ccactcggac
     8161 atcgtcctgc gcgccctgct gacggcccgc ccgccctggc acgtggtgag cgtgagccag
     8221 gagacacccg acccttccga agccgagagc cgccgatgac cgccctcctc tgctaccagg
     8281 ccgcgctgct gctccgctcg cagcgctggc tgccgccgtt catcctgtac gccgtcttcc
     8341 tcgccgtcgg cgtgcagggc ggccagccca tcctcgactc gctcggctac gcggccgcgg
     8401 ccctgctgcc ggtcgccgcc tggctggtgc ggatctgcgt caccaacgaa ccgccggccg
     8461 cccgcagctg tgtgtccgcg gcggtcggac cggggcgggc gcacctcgcc gcgctgctgg
     8521 tggcgctggg cgcggcggcg atgctcggta cggtgacgat cgtcgtcgtc acgctggtca
     8581 gcgacccggc cagtgccgac caccagaccc gggtgccacg gctgccggcg ggtgccgcgg
     8641 gcctgctcgc cgcgctggcc tgtgcgctgc tcggcacggc cgtcggtgcc ctcaccacct
     8701 ggccgctgct gcgctcgacc ggccgcgcgg tccccgcgat gctgctcgcg gcgctgctgt
     8761 ccgtggtggt gaccggctcc ccggcccagg cggcggtcag cggcctggtc accggctccc
     8821 gctcgggcac ggtcccgctg cccgtcctgc ccctggcggc ggcagccctg ctcacggcgg
     8881 cggcgatcgc ggccgcctgc gcgctcacct cgcgcagatc accctgagca ggccgtgcgc
     8941 tgcgcctcct gccactcgca caccgggcag agcgtgatcc ccttgtacga ctccgggtac
     9001 tccgtcggct cccggcacag cacgcactcc gcgtacggcg gcccgtcagc cctgggcggc
     9061 ctggtcgcgt cgatcaggca gtagtcggtc atgggctgtt cctcgctcat accttcagcg
     9121 tacgagcctc acagccggct gctcgcggcc ccgatcagct cggacacctt cacgaaccgg
     9181 aagcccttcg cgcgcagtgc cggcacgatc gtccggaccg cccgttcggt cgtcggagcg
     9241 gcactgagcg tgcagtgcag gacgaccacc gaccccggcc gcaccccgtc cagcacctcc
     9301 cgggccaccg cgtcggcgtc cgtcgcgaac gcgtccccgc tcaccacgtc ccactgcacg
     9361 gccgtgaccc cgaccggggt cagcgccttc agggcgcgcc ggtcgtagca gccgccggga
     9421 aaccggaagt acggcatcgg atcccgtacg cccactttcc ggaacacggc gtaggcccgt
     9481 tccacgtccg cccgcatccg ctcctcgtcg agggtcggca gcccgtagca gtcgtcggtg
     9541 aaggcgtagt ggctgtacga gtggttggcg acctcgaaca gcgggtgccg cccgatggcc
     9601 cgggcctgca ccggatactc ctcggcccac cgtcccgtca tgaacacggt cgccggcacc
     9661 ttcagctccc gcagagccgc gaccagcccc gggttgtcga accgctcccc ccgcgccgcc
     9721 cgcgtcccct ggtcggcggt catgtcggca tcgaaggtga gcgcgacggt cttgtcccgg
     9781 gcccgggggc cgtgctcgaa gacaggggtc agaccggcgg gcccgggggc gagcgtcggc
     9841 ggctcggcgg ccggggagac cggggaggcg gcggaggcgc tgggcgcggg atgaggagca
     9901 cgggtcgcct cgggcgccgt gcacccggcg agcgcgccga gggcggctcc cagggcacag
     9961 gcggcggcgg tgacgcgtcg tacaagagtg atcaccgaac gaacatatga ggatcaaatg
    10021 gttatttcgg tggatcagcg ggtgtgccgg gccggtgtca cccgcccggc acatgcgcgg
    10081 cctctctcac cacttccagg cgaaaccgac ggacgtctcc tcgatgaagg gaacgtagtg
    10141 ccggacggtg ccgttctgag gggtcatttc cttccgctgg accggcacac cgcccaggtg
    10201 gtcgtcccaa acgcaccacc acacgacgcg cggcgttctc ttcgcgggaa acaccaccgc
    10261 cagatcgacg tgctccgtgc gcgcgaaggc ggcccgtcgc acttctgtcg cggggaaggc
    10321 cggttcctgg acgaagtgag tccggtactc cagggcggtg gtctgggatt tcaacagggg
    10381 aggcgtgagg atgatctcgc gcccgaccat gccgccgccg tagacgtgtt gcaggcccgg
    10441 cgttcctccg tgcagcacct cgatgtcgga cgcctgcggt tcgtgattga acatatagag
    10501 atccaccccg tcctcgatcg cacggatggt gtggaaggtg ttgcggagct tcagcgcccc
    10561 tgactcgtcc aggaagtacc gctccaccag gctgacggtt cgatggcgct gcctgctggc
    10621 catcttccgg cgtcggcgta acgtgtgcgc gataccggga gtggatccca actccgctgc
    10681 gtaggtggcc cacaagtggt cggtgtcacc gctgtccatg tcgaaggcgt tgatgatcca
    10741 cttgagcgtt tccgcggata tcgcagttcc gttgagggcc cgggacaccc tgtccttgag
    10801 ggtccgctgg agcgatgtct cgctttcact ccgttccccc gattcccaga gatgcaaagt
    10861 gatgacgcgc gcgaccgctg actgactgag gcctccccgg acacgcccgg tcttgccgag
    10921 ccacagccgt tgatagcgtg gcttcgtcgc gaggaggtgc tggagcagtt ctccagtggc
    10981 aggaaaactt cgtccccttg aagccgacac cgatgacctc caagcctgtc cgcggacagt
    11041 agctccctgg tagtccccgc cctgactcac ggcttcgagt atgtggcttc ccagcagcgg
    11101 cttctgcact tcgacgcttt tcgcacggtc tgtgcgacat aagcgcgaca ccgctgtcgt
    11161 gaagttgtgc tcggcgcgcc gaaccgtcag ggagggccgg cgcgtaacga acgcaacgga
    11221 ggagaagagc ccgtgagcga caaggacacc aggggagccg acaccgcgcc ggagcacatg
    11281 accgccggag aggaggcgga cggctcggac cccgtgcgcg acagcgccgg cggtaccgca
    11341 gcgcgcgcgg acctgctcgc catgc
//
