LOCUS       NZ_KQ947985            26329 bp    DNA     linear   CON 21-APR-2024
DEFINITION  Streptomyces curacoi strain DSM 40107 PRJNA299217_s002, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ947985
VERSION     NZ_KQ947985.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces curacoi
  ORGANISM  Streptomyces curacoi
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 931730)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Draft genome sequence of Streptomyces curacoi DSM 40107, type strain
            for the species Streptomyces curacoi
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 931730)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-OCT-2015) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 13-OCT-2014
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 65.7x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001513975.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 02:05:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,531
            CDSs (total)                      :: 7,455
            Genes (coding)                    :: 7,251
            CDSs (with protein)               :: 7,251
            Genes (RNA)                       :: 76
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 204
            CDSs (without protein)            :: 204
            Pseudo Genes (ambiguous residues) :: 0 of 204
            Pseudo Genes (frameshifted)       :: 91 of 204
            Pseudo Genes (incomplete)         :: 154 of 204
            Pseudo Genes (internal stop)      :: 21 of 204
            Pseudo Genes (multiple problems)  :: 54 of 204
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:06:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 37798
            Orig. end                         :: 64127
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ947985.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26329
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26329
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26329
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16329](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16329
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    884..899
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 22.89"
                     /tool="antismash"
     misc_feature    1578..1587
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     misc_feature    2564..2579
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.9"
                     /tool="antismash"
     misc_feature    complement(2979..2994)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.83"
                     /tool="antismash"
     misc_feature    3262..3276
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.97"
                     /tool="antismash"
     misc_feature    complement(3300..3315)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.96"
                     /tool="antismash"
     misc_feature    3308..3322
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.38"
                     /tool="antismash"
     misc_feature    3309..3321
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 18.52"
                     /tool="antismash"
     misc_feature    3411..3420
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     misc_feature    complement(4358..4372)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.41"
                     /tool="antismash"
     misc_feature    4473..4488
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.42"
                     /tool="antismash"
     misc_feature    4473..4491
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.53"
                     /tool="antismash"
     misc_feature    complement(4475..4489)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.65"
                     /tool="antismash"
     misc_feature    complement(4476..4491)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 21.41"
                     /tool="antismash"
     misc_feature    complement(5994..6008)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.8"
                     /tool="antismash"
     gene            complement(6490..7029)
                     /locus_tag="AQI70_RS05635"
                     /old_locus_tag="AQI70_05630"
     CDS             complement(6490..7029)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337821.1"
                     /locus_tag="AQI70_RS05635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05630"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_208607299.1"
                     /transl_table=11
                     /translation="MTTAPSIELRTFTTLDTARGDLLDVYADVRAPLLHLPNYAVTAFG
                     ERLDRHSTEPGFTAVLAYADGHPVGYAYGNTIEHGDRYWQRTTPTPAEKYTERPAVALK
                     EIGVRPTWRKTGTARRIHDALLATRDEPYVTLMVNPAAGDGKVHALYKSWGYEDIGQSQ
                     PSPASPVLTVMIRIIR"
     gene            complement(7026..8309)
                     /locus_tag="AQI70_RS05640"
                     /old_locus_tag="AQI70_05635"
     CDS             complement(7026..8309)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000004.1"
                     /locus_tag="AQI70_RS05640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05635"
                     /product="Tat pathway signal sequence domain protein"
                     /protein_id="WP_079051164.1"
                     /transl_table=11
                     /translation="MDTTRNTVLEAWMTEHGYSSNSLAEAVNRAIERLTGRLGGLDGSS
                     VRAWKAGRVTWPKSAARKALEDVTGLPAIALGFVPRSRPSSTPAPPQQEDPDMKRRTLV
                     GSIAAAAAAAAAPGTASPRRIGMSDVNRLNKRFAEIIASDHRHGGQLGIEQRAAALADE
                     ALNLQNAGSATQRVRSNLYASAAAFRSSAMWAAIDGRRYDVAKAHMREAQALAEMSGDQ
                     AIKFRIWSHAGTMYRHMGRPADAFAANDVARNLHLTRRDPLFASLGLARQAAIHGTAQD
                     RTGTRRAFEQAQDAMLRADPADYRPVWMLAFYDQAELDSLALSAHLALGDYSTAEYHAH
                     RCLSALRPHMIRSRAITTTRLAHAQLAQGAPDAATATAMKVPAEAATQHARVTRMLQEF
                     GAALRATAPGSSTVQTWTEHTAAWRMAA"
     misc_feature    complement(8082..8084)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8551..8997
                     /locus_tag="AQI70_RS05645"
                     /old_locus_tag="AQI70_05640"
     CDS             8551..8997
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000003.1"
                     /locus_tag="AQI70_RS05645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05640"
                     /product="ATP-binding protein"
                     /protein_id="WP_062145161.1"
                     /transl_table=11
                     /translation="MTSLKTPVEALSVGHPTYSQTFPCKPSTAELGRELVRDVLGVWHL
                     DGLADRAALIITELIANASRHTPCPEIRLTVGRPSATRLRVGVVDREPSRLPILSQAAD
                     DDESGRGLLLVDAVADRWGYDLHGSGRRPWGKEVWAELRTGGGE"
     gene            9604..9783
                     /locus_tag="AQI70_RS05650"
                     /old_locus_tag="AQI70_05645"
     CDS             9604..9783
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825826.1"
                     /locus_tag="AQI70_RS05650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05645"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_062145163.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 5.4e-14, bitscore:
                     47.6, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSTVVPSRTEVRPQIRGASDGFDLDVSLVEIADPAGLVNLTDD
                     NCGSTCGACTTNVA"
     gene            10001..12955
                     /locus_tag="AQI70_RS05655"
                     /old_locus_tag="AQI70_05650"
     CDS             10001..12955
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543779.1"
                     /locus_tag="AQI70_RS05655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05650"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_062145165.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.9e-199,
                     bitscore: 659.6, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2.7e-20,
                     bitscore: 68.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 7.7e-22, bitscore:
                     73.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAWLRAVWADTDVAEALQHSSPVLATQVGALCTAEYPALRDVRRA
                     VLSVARYLLRTQHRATPFGLFAGVATAEFGPQARADWGEEHVAVGRAGAEWLAALVARL
                     ESCPDLLERLPVVINNTVTYRGDRLIVPFQPDVQDDRTRPVEASLALTGPVHAVLAATR
                     LPIRFGTLVDKLQAEFPEAGPEKARQLLAELIRRRVLITGLHAPSTETDALGYLLGQLD
                     AIDAGTLAPVAETVRELRAVRAGLEECATHGGRDSVAARMRDLVPGLRRHPVALDLRLD
                     AQIVLPEAVAREIERSALILTHLSIRPYGTAAWNAYHQRFYERYGIGTMVPLVEAVADS
                     GTGYPDGYPGASASARRPRVSARDDALVRLAQAAALDGRDEVILTDEQIEALDAGPDEP
                     RLPPHLEIGVRVHAASLEELQRGRFRLEVVSVSRGVGVSTGRFLSVLAPADREALVAEL
                     AGLPAADGNTVPAQLSFPPLLPESAHVTRSPQVLPTVISLQEHRAPQDTVLTPEDLAVG
                     CDGRRMYLAVPERGHRVEAVGVHALNLRTHTPPLVRFLTELSRAQCAQVTVFDWGAAAA
                     MPFLPRLRYGRTVLAPARWRLEVSELPGHARPRAEWDAALSDWRARRRLPRRVHLVEDD
                     RRLFLDLDEAGHRALLRRHLDHRRLAVLVEAPEPEAYGWCGGRAHEVVVPLKATRPSAW
                     PPLPAPSRARALSAAQMQTPAASSVVLAALYGAPRRQDVLLSQHLPGLLEQLGNPPWWF
                     IRFRDPDQHLRVRIALPDPEAFADTARTVSAWADELRSIGLLADLRYPTSYREMGRWGS
                     GTAWEAAEEVFRADSRAILVQLAQPQRPGLRTLVVAHTVAIASAFLGSTAAGMRWLIDH
                     IPPTAPAPVPRPQFTDAVRLADPSDDWAALRQVPGGDAIVSGWADRDAALAAYRPHLPG
                     PDTQGIAVDDVLTSLLHVHFVRHVAVNFPEEEVCLYLARAAALAWTARTRGRAS"
     aSDomain        10346..10621
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AQI70_RS05655_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="8.80E-22"
                     /identifier="RREFam001.1"
                     /label="AQI70_RS05655"
                     /locus_tag="AQI70_RS05655"
                     /protein_end="207"
                     /protein_start="115"
                     /score="68.6"
                     /tool="antismash"
                     /translation="VVINNTVTYRGDRLIVPFQPDVQDDRTRPVEASLALTGPVHAVLA
                     ATRLPIRFGTLVDKLQAEFPEAGPEKARQLLAELIRRRVLITGLHAP"
     gene            12952..14226
                     /locus_tag="AQI70_RS05660"
                     /old_locus_tag="AQI70_05655"
     CDS             12952..14226
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543780.1"
                     /locus_tag="AQI70_RS05660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05655"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_062146436.1"
                     /sec_met_domain="LANC_like (E-value: 5e-43, bitscore:
                     142.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTHPALGLVDAIAAQLADPDTVPRGSRALSSDRQHLAYGPPGIA
                     LLHIELAANGLGPWHRAHDWLAAASRQPLTSGPASHPFYGVPAFAHALTCAADHLPGSY
                     QRALDAMDAQIAVDVGRRLDAAHRRIDAGRLPQLAEFDAIRGLIGYGAYLLRRNPGSST
                     MRAVLDYCVRLTEPITHHGESLPGWWAETGPSGSPDDRFPGGHANTGMAHGIGGVLALL
                     ALAARNRSVTDGHHAALRTILAWLDRWKEKTSGGPVWPYWVTQGELRSGRPGSSAPRRP
                     SWCYGTAGLARAQQLAALALGDASRQIAAENALVAALTDPEQLKATTDNGLCHGFSGLA
                     HAAARTADDAHPSTAGKLRAAIPTLLAAVIPPGTDPELMATALIQDEEGGPGLLDGAAG
                     IALALLAPSTAAPHRSAWDACLLIA"
     gene            14248..16329
                     /gene="fxlM"
                     /locus_tag="AQI70_RS05665"
                     /old_locus_tag="AQI70_05660"
     CDS             14248..16329
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543781.1"
                     /locus_tag="AQI70_RS05665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05660"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_062145168.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.9e-28, bitscore:
                     95.6, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 6e-46, bitscore: 152.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPDRWQQHNITFVDREIAQRTIAERLGPTLIEAEADGQLTDWWF
                     MNKQPWPLRYLADKPSPAIESLLSDLVRDSVAVSCLPCVYEPETDTFGGPEAMDTAHEL
                     FHSDSRHLLTYQLSPMHLGRRETAVLLASVMMRGAGLDWFEQGDVWAKVAALRPATAPQ
                     PPERTAELTPAMRKLMTADAHRLCRPGSPLHAHEEWVTAFERAGATLADLAARGALTRG
                     LRAVIAHHVIFHANRAGLLRDDQSALSHIAREVVMGTSDHTESPTEATAEIDSVSAVNP
                     DTIATPTADAERLRNALVDQLRADGHARTPAVETALRTVPRHVFVPDASLEDAYANAPV
                     HIKYDTHGTSISCASQPGVVALMLDQLDAQPGQRVLELGAGTGYNAGLLAHLVGESGHV
                     TTLDVDDDLVEGARAHLAAAGITNAEAVTRDGALGYAEGAPYDRIIATVGAHGVPHAWL
                     QQLAPGGRLLVPQRLKGTVSRSIAYEQRDGRWVSLGSEMNTFMPLRRGIADDDRRVIPL
                     STDGTVRLQAPAGLNIDADALAGVLDQPRTEEWTGMTVRAMESPEWMELFLTCSLSSGL
                     IRMLFPQSAKGTLLTEDPYPSSTAVVDQGAVTYLARRLSEKRTPEGGKLWEFGVIGHGP
                     GSDELAAKVADAIRTWDREYRSREATFEIQPLDAPSIERRPGLFALDTPLNRIVVDWQ"
     misc_feature    14278..14292
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            16418..17550
                     /locus_tag="AQI70_RS05670"
                     /old_locus_tag="AQI70_05665"
                     /pseudo=""
     CDS             16418..17550
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999997.1"
                     /locus_tag="AQI70_RS05670"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05665"
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDPHGSTAQRFPLVARFRPACLPLPERVRALVDLADTAVKETDQG
                     LASAVYNQAALIASDLGLPDLAREMCHQHAAAYLHACPLPGMSAIRGLEPVVNLARLQI
                     RAGHADEGRQRLLNLYKAVEAGAAARFERVTVPASLTATGEDRQEVRAWLWRVLLADGT
                     RTLTTEGQWAEALAHIEAHHGIGKRMLDGRQVAVLAALVAGDTAWAAALLADTMPGGPW
                     EQAVTTCLTVLCRRDAGQPIDGHLADLVTVYSRRKTEPG"
     misc_feature    17228..17230
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17557..19272)
                     /locus_tag="AQI70_RS05675"
                     /old_locus_tag="AQI70_05670"
     CDS             complement(17557..19272)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002506.1"
                     /locus_tag="AQI70_RS05675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05670"
                     /product="hypothetical protein"
                     /protein_id="WP_062145170.1"
                     /transl_table=11
                     /translation="MIAAIKPAGSNTRGLLAYLYGPGDHDEHLDPHIVAGFAMLGMPDP
                     GRDENATLTELARYLDQPVRLRNSEFGGKVTDHVWHCPVRAAPEDRYLSDTEWGDIAQR
                     IVQAAGIAPAGDDLACRWIAVRHADDHIHILATTVREDGRRPKLHDSGIRVGDACREAE
                     KDYGLRRLKKGDRTGTRRPTQAEMHKAERLGWEQPSPEWLQARIRAAIPHVTNAGEFIA
                     YLEASGVEVQVRRGPSGDLLGYAAGRPGDVNEAGEQIYHPGSKISPDLSLPKIKARLES
                     SRPEEHPTARRNHPSTPWRQATDALDTLHSDLAADTHAQAHITALGELLEATAQKVPAN
                     LRTELQAAAKAFARAQRSQIRAEDRAAHALRSAARDIVHTATGPDGSALAAMVAALVWA
                     TIVARRWHEAKHHAHQADAAGQAVQHLQTAADRALAPTLAELTARPPREQTRRVFANDV
                     RAAVPDHAERILADPAWPALATVLADAEARGHQPHQLLKEAAVQRELTSARQPARVLIT
                     RIQHTGRNPAPNRRAEAARRRSTITPSVRVQQIHNGQLPSAATTPAEQQHRWRR"
     gene            complement(19269..19838)
                     /locus_tag="AQI70_RS05680"
                     /old_locus_tag="AQI70_05675"
     CDS             complement(19269..19838)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005476783.1"
                     /locus_tag="AQI70_RS05680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05675"
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="WP_062145172.1"
                     /transl_table=11
                     /translation="MAEMAQRQGAPGQHVGAEGGPDEDTLHTVQRETLRPVRATDTAES
                     VGGEPVVKSVQPTIRRFTGTKRVVRVGPLRFTGDEHTQLQEAAAEHGYKGDSGFAADIV
                     LAFITGRFTANLPLSEDRRRTHIFRAQVLRQLNRIGVNVNQIARALNSDRTPPDIRQRL
                     TELHDLLELIAEALCQPTDPGTESAA"
     gene            complement(20184..21014)
                     /locus_tag="AQI70_RS05685"
                     /old_locus_tag="AQI70_05680"
     CDS             complement(20184..21014)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009321524.1"
                     /locus_tag="AQI70_RS05685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05680"
                     /product="DUF2637 domain-containing protein"
                     /protein_id="WP_079051219.1"
                     /transl_table=11
                     /translation="MAGVVIVALTAGAFWLSYAHLADVAAQHGLRDSPTRRWAWPATLD
                     AFIVAGELLMLRAGLRRVKDKWAIGVTAIGSVGSIGLNVAGVTGTRDIGSVPLLDYVVA
                     AVPPAAAMVAFGVLMRQIHELVTQPAAGHPDPDSAHVPQLPATTSVHPAKAPATAVGPS
                     AEAPAEGVRPADLVVQPGRITGLPIAVSGQSPESPSQAAEGKPRGGRPPGAPLEVLVEI
                     GRAAAAEQGKLTRVVVRTAVEAKGLTIGSKRLTEVMDILRAELEAPAETDRDGG"
     gene            complement(21581..22909)
                     /locus_tag="AQI70_RS05690"
                     /old_locus_tag="AQI70_05685"
     CDS             complement(21581..22909)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015578055.1"
                     /locus_tag="AQI70_RS05690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05685"
                     /product="DUF3631 domain-containing protein"
                     /protein_id="WP_062145174.1"
                     /transl_table=11
                     /translation="MQPENPESYSAPAKATWPATAVPGRPGAHLRATQADDADPDLSGD
                     ADARSADEAETPSGPDAIPDAEPTHGSKLLDELRAQIAQFVIPPSQEALDAITLWVAAT
                     HLQPAWQHAPRLAVVGPAKRCGKSRLLDVLTETVHEPMLTINTTPAAIFRSITEENPPT
                     LLVDEADTIFGTPKMAEKNEEMRGLLNAGHQRNRYVTRVVGNDHTPHRFATFAMAAIAG
                     IGDLPDTVMDRAIVIRMRRRAEGEKVKPFRSRRDIPALHDLRDRIAAWARPLLDEAANL
                     EPDMPVEDRAADTWEPLVIVADLAGGRWPRLARVACVRMVAAEEAAEEDHPSGARILAD
                     IRRVFYSQREVDSLSTEELLHHLRQDPEAPWAEWGRGGLAARELSRMLRTYEIKSGNVR
                     MADRTQRKGYMRNKFLDAWRRYCPTVHPVDTQAAPPGEPPAVH"
     gene            complement(23143..23373)
                     /locus_tag="AQI70_RS05695"
                     /old_locus_tag="AQI70_05690"
     CDS             complement(23143..23373)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961488.1"
                     /locus_tag="AQI70_RS05695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05690"
                     /product="hypothetical protein"
                     /protein_id="WP_062145181.1"
                     /transl_table=11
                     /translation="MRENELAGRVKGMSREELLELPAAVDLETGNRALGLGRSKGYELA
                     KRGQYPCKVLRLGNAYRVVTADLLALPGLAA"
     gene            23468..24154
                     /locus_tag="AQI70_RS05700"
                     /old_locus_tag="AQI70_05695"
     CDS             23468..24154
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009321526.1"
                     /locus_tag="AQI70_RS05700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05695"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_062145183.1"
                     /transl_table=11
                     /translation="MTQHGWDAGGDEDDVPEWVDQVMATVAAEVRRRRKELGMSAQDLA
                     DRCEEIGHPIPRNVIANMESGRRANLPLVDVIVLAEALRTYPICLLYPVGYVDRVQRLP
                     LQHSEPAWDAMRWFTGDSEDFGLEDDMLRSFRAHVRHQRAALAALKGEKHERWKAETAP
                     NRAEREEAVLAQADYAERALEAKYRLRSARAFIREDGGTPPHLPPELADVDPPETDPST
                     TEENDL"
     gene            24151..25662
                     /locus_tag="AQI70_RS05705"
                     /old_locus_tag="AQI70_05700"
     CDS             24151..25662
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015578052.1"
                     /locus_tag="AQI70_RS05705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_05700"
                     /product="site-specific integrase"
                     /protein_id="WP_062145185.1"
                     /transl_table=11
                     /translation="MKGSTHRRCCCRDPHTGKPLGKKCPKLSSRKHGSYSIRQELPPRE
                     DGTRRSFSRAGYESLKDAQADLDHVRSLLALAEKDDPDSLQRLVDMLEEVAVEKAPLPA
                     IEETRRRLRAGLALRGSLTVGEWLDQWFAAKKRRKTTLNGYASHIRVHLKPRIGHVRLD
                     RLNVGHLVEMFDGIADDNEVIAAENEARREQIARCKPSKPGRPVGAEQKLLAIERAKLA
                     EMKPFRKITGPASRQAIRRTLRAALNSAIAQQLITFNPASHVELESGKRPKPLLWTDER
                     VRRWRATGEIPGPVMVWTPQQFGAFLDAAEGDRLYAIFHLMGTRGLRRGEAVGQDWHEI
                     DLDAGLITPAKEIVVDGWDPYESEPKTDGSANTIALDSTTIMELRDHKVRQEKERAQWG
                     DAWQDTGKVFTKEDGSWLHPETVSETFRRILATTDLPPITLRDLRHVAATLTHGGGGDI
                     HAVKETLRHSTIALTSDTYTSLLPELDREIAEAAARLIPRARQPR"
ORIGIN
        1 gaattgagtg cctgccgcgt tagcagacag atgagcccaa gcgaaaaagt ccgtgaaaag
       61 tgagcgttga gcggtagtga ttccacccgt cagcgggtcg tcgcggtcta ggccgccgtc
      121 gtctgactcg cgataaacga tccagccgag cagttgcagc ttgggttcat ctatttcgtc
      181 tccccatggc ggcccctcgc cagccccagg caggccctgc ggacgtgtgc tgcttgccag
      241 agcagcgagt agggcggcac tggcttctgg ggttactaga gcgctggtca accaggccgt
      301 acacgaatgg cggtcagaat aggtggtgat ggatgcggac actacgatca tttcgggatc
      361 gtcatcgagc atgtccagtt cgcggcatgc ctgtcgcgct acagcggctc cgtcgaatcc
      421 cctccgaact gctgaatccg gatcaacagc agacgtggaa gcatcctgag acgtcgtcgt
      481 ttgcactgag gtaatggcgt cgtctagctg gagccgatcc cacataccga gggtgagcga
      541 gcgagccgga accggttcgc ggatatcggc cagccagtgg gttgatgagt ggggaagatg
      601 accggtcagc cagcccgtcc actcgtcgtc gtcacgccag tgtctgagca cggggttttc
      661 cccgtcgata agttcgccag ccaccatgtg gagtgcgtgg tactccaggt acttctggag
      721 cgtttccaca atcggcaagg aaccatggtc agcactgatc agcgcccacg accgctcgtg
      781 ttgggccgcc ctggggtcct gccgtgtttc ctcggagctc cggccccacc gctcgctgat
      841 ccacttgtct gcactctgca tgacgtcggc gagaaacact ccgtcgaatg cctctgccag
      901 aggggagtac cagtacggta cgacgtccat agagtcgaag tggaagcgcg tgtcgtagtc
      961 gccataacgc gatccaacgt tccgtacgtc gcgtgaggtg ctgcacaatc gaggccgatt
     1021 cgcgaacgcg aggtcgctga caacgtgcgc aggcaatgcc tcaggatgag ctgcggccac
     1081 gtcgagcgcc gcttggcgtg ccaactcgcg aatagctgca tggggctgac ttcggtctac
     1141 tgccattgcg gctagttcag tggccagcgg cactaggacc agtggggctt cactggctac
     1201 ccgcgcgaag acgatgagca gccactgttg agctgatagc ggaaagaatt caagcgtggc
     1261 ggaacggaaa ctaccaccgg tggagaattc cgttacgcag cgccagagcg cgtcagccac
     1321 agagctgccg tcgctgcttc gagtcaggat aattcgtgcc gtgtgtgcag ctcgccatcg
     1381 cacgcgccgg tcgggatggc cgagcagggc ccacaatacc gctgcaaaga gtgtgctcga
     1441 gtcctctggt ggttcaggca aggtctctcg ggcggccttg atgtcagctg cggaattact
     1501 aatcgccgaa gcagcgggaa tccgtgtgat aggtgcagag ttgggtagag acggacgaga
     1561 gtccaaagcc cattcgatga tttgtgaaag tgtggacgtg gccggcagtg tttctgccag
     1621 tgatgctgcc aacgtgtaaa gctggttggc agtcaactca tcgaggtgag cagatgctga
     1681 cggaaggagc caatttgacc atcccggttc attacttggc aattttagca ataggccgta
     1741 gttgccatgc cgatctagtc cggtggtgaa taggtcgagt agatgtcgcg atacccacat
     1801 cggcagatgc tggctagccc agtcacgcac gcttgcgctc gcacgccatt cgtagcatag
     1861 cccgctcact acgcgcgcta cctggggtgc gcgggcgccc cgcaccccac gatcggcgag
     1921 ttttaggagc tcctccagcg ccgtagtacg tcccgacggg ccggcgcgat gagccgcagt
     1981 cgtcaggtag gtgactacgc gttcatcaga ggcataatga gcgacaagta cggggagatc
     2041 ctgatcggct cggatgaaac tcgccgcact gactaggcca gcaatgtcca ctgcttgctc
     2101 ttcaccggat cctccccagt cccgtgagga gcggatggct ggcttatttg cgcttagggc
     2161 ggaaagttcc tgtgcacggg attgcagtcg ctgcgcggcc tgaatctgac ccagtcccat
     2221 ttcttgaatg gcagtattga gattacggga agcgtcacct tgttggtgag gcggtagatc
     2281 gcgaacgacc cagtcggcga gcgttccgag gcacgtgacg gcctggctac gacccgccgg
     2341 tccctggttg aggaggcatc tgagaacagt gaccgcaggg gttaccacat cggagtgctg
     2401 actgagcagc cgcagcatcc agaacgcctc aaagccgccg actgttcctg tctcggcgag
     2461 gagaggaatg accgtgccaa tgccttcaga taggcccacg tgtccgtcgt cctcccaccg
     2521 gcaggcgaga gctagaccag acggcccgtg gagtcggctc gccacgctga gagcgagccg
     2581 gtatggcact tgttcccgag ggtccggcac aaagggggtg gcgtcttcaa ctgcgtgggc
     2641 gagccgacgg gcgatgtgtg cacggtctcc gcctgttgtg gggtctgttg gccgatcggg
     2701 gatccggtcg gcaatcgtga gcagagcccg tagcctcagg gcgacatcca cgtccacgcc
     2761 gctggcggca tctactgcgg cagcgaacag gtccgcggcc agagccgtgt cagcgtgttg
     2821 cgctgccgcc gctgcgtcca ggagtacgtc ccgccgttct gttgccggga ccgtcgctgc
     2881 acccatgacg tctcccaccc gctgaagtag ctgaagagca acttctcggg cgaccccatt
     2941 ttcaaggagg atacggctca tttgcaccca cgcgtatgcc gacccgtcgg ccaactgctg
     3001 tccgatgctc ttccctacgt ctgccaacag attttcgatc tgcatctgca tggcatttgc
     3061 ctctatgctg gtgaacgcgg ccatggcccg tgcagctgat accaatgcct cgaccgcagc
     3121 catgaaccag acgcgttggc gattaccagg ccggtcgaat ctatgctctg atccctgggc
     3181 ctccacccga ctacgcacga cctgtacgac ctctgcagtt gccagctcga catcgtcagc
     3241 gcgggattta cgatcggcgg caactttcac acattcggcc tgtgtagtta ctacaggcag
     3301 caagtcatta gcaatctgca agaaaagccg acgtgtggac tcattcttgt cataacttcg
     3361 gtcattatcg gtcggtggcc gcaaattgtc tgggagcagc ttctcagctg tgattttgga
     3421 gccgcggatg gcggcttcca ggcatgccgc cttcaacgga ctaagcatct cgctgctgcc
     3481 ggtgtaacta ttgaggtgag acggtactgg cggcgcaaag cgccggagta gacgtctcac
     3541 cttggatttg gcggcaccat gcgccagcgc gatctcacag aacggcatac cccactcggc
     3601 tggatggctc accgggcgca gaggcaaccg gtctagccgg gtcgcaacct gcagtaccca
     3661 cctgccgggc agactttccc cggcccgtgc gtaggcgact gcgaactggg cctgggtcca
     3721 tgcactggct cgtacctgat tcaggtcccg aattgcctgc ttgacgggca catgcgcagg
     3781 tgcatgttgg gccacgtgcc acgttacctt gtcaacgaat tggggcggat tccagccggc
     3841 cgccaggcga tgggcgcgat ttaggccacg cagcacgtat gccgcatgta cgccgtaggc
     3901 gatgtcctct gcgctcagtt cccagcccgc gtcctgccgc gaccaggccc gcagccacgc
     3961 gtaggcaagg tcgagttgct cgaccgcctc tgccgtacgt ccgttcagcc atgcaagcat
     4021 ggctgcggcc cggaagtgag cgcggcctcg ccaagtgccc gattcttctc gcaacaagat
     4081 ctcggcgact gtgctcgcat ctgcatgtag caatgcgagt tccggccgct gacggaccgt
     4141 gtcaacgagg ctggaatcgg tgcgggctgc gtcccctgca gccagcagga gtcggaccgc
     4201 atctccggat gcgttgttgt cattgcgctc catgaccgcg cgcagtgcca gcgtgagccg
     4261 ggtccgttga gcttgggctc gtgctatgcc gtctgcgatc gccgctggcg cgccttcatc
     4321 aagtgctatg gcgagcagtt cttcgtggcg gccggagtta aaaagatgct caccaaccag
     4381 tcgtgctgct tcctcgtcga catggcggtg gtgaaggaag tcctcagcaa agagatcgtg
     4441 ggcctggcgt acatcggaca ctgacaactt ttgacgcaaa tgattctcaa agtcctcgtc
     4501 ggcgaaaccg acggcgccgt cggagattcg cagcgccgga aacaagtcgt cgcacagctg
     4561 ccgcacgcgg ccttcgttgg tcttcagtac ccgggcgagt gtcgagggcc gcgcagggcg
     4621 ggccatggca gcaaggacgc ccatgtgctg ctgccgcacg tcgcggtcat ggacggtgga
     4681 gaaggcgcta tctaggacct cgtcgaagat ggctgccagg ccggcttccg cgcgtacgag
     4741 tacgtcctcg atatccagca tggctggggt ttcactcgtg ccttgtgacc gctgctcccc
     4801 agcgcccagt gcgtatgtct ggacgcgcgc cactccgttg ctggcggcat ggaaggccgc
     4861 gcattggtta tccgttgcgt tcggatacat cgaacgcaac atcgccgcgc tggccgaggc
     4921 atcaaatgcg ccaagtgctg tctcagtgat acctgtctct tcggctccag ccaggacgtc
     4981 cgagcgacga gcgctgcgtg cagtcatcag cactcgcacg ttaggcggca gttgcatgtg
     5041 ccacagccca cgcacgaacg gttcagctcc actacggtgc gccgcgaaaa cggcgttatc
     5101 ggcagcatcg actgcgacaa cgaggagggc ggactctggc agtgcgtctg ccaccacggt
     5161 gagcgttctc tcaagtcctc gccaaagctc actgtggacg actggcccat cgggcaccac
     5221 caagggcaga gcgccgcctc gaaccgcgac gtcgtttgcg atctggacaa cggcccgttc
     5281 gctgtgccga tcgttggccg gattgaggta ctggccgtcg ccgtagcagt cgtacgcaac
     5341 gaggatcgat cctggtggca gttcggcttc caacgcagtc agaacggttg tcttgccgac
     5401 acccggccca ccgtgcgcca ggagctttcc ggccgttgca cccgttacag ctgcggccag
     5461 actctgcggc tgggccgttg gtacaagctt cttaggcttc gccacaagtg tgggataggg
     5521 aaatagcgat cgttccccgc ttgcacccaa agcgacgatg atgtcagcgc gactcagccc
     5581 agggtcaccc gctgtttctg ggagcatctg ctggcgcatg agttctatca gcccgatgac
     5641 tccaggacgg gacgagccga cgaggaagga ggatgcctcc tggtggagtg tcagcgtctg
     5701 cagtgcccgg ctgtcagcgc cacagccaga aaggtccaat acccgaacaa aatcagtaaa
     5761 ccgaccactc ttcagcccgg acgccgaacg caacttggtc aagatctgct ggtgaggctt
     5821 ggccagtgaa gcaaaggcgc gtcccgcgtg cgcacccagc ggtcggtccg ccagtgctgc
     5881 ctgggccgat ttcagcgcat tgaggaggtc gacgtcggct ggctggttac tcaccagtgc
     5941 gacattgatc ttgcttacta cggtcgacgc atcccagtct tctgctagcc cgctgaacat
     6001 gtctgccaag cggcgaagcg gaggtgcacc gccaggggtc ttggcctggc acagtctggc
     6061 cgccgtccag gctcgacctg agtgcttgac gctgtatttc agctgagtca aaaccagacg
     6121 attcgctgtc gcgaaggtgt ctccgccgta gtattcactc aggtcgcagc ccaagtagcg
     6181 atcatcttct tcggctgcgt cagctggtga tagcccctcc aaccgcagaa tcctcaggtc
     6241 ggtgtggggc atcaggagtt gcaatgcacg ccgggctgcc catagcaggt ggaaatcatc
     6301 cccggctcgt gattcgcgaa cagaaatgac tcgctccgga cggatcgggc acgcaatgcg
     6361 cgctactagc agacctagtt cattgtcccg cagatcagca gaccaggacc cgcggagcga
     6421 gtagcgatcc caaactgacg gtcaagatct actgcgatcg gctctgtaac gaatggagag
     6481 acgtcgggat cagcgaatga tgcggatcat caccgtgagg actggcgaag ccggtgacgg
     6541 ttggctctgc ccgatgtcct cgtaccccca cgacttgtag agcgcgtgaa cctttccgtc
     6601 gccggcggcc gggttgacca tgagcgtgac gtacggctcg tcgcgggtgg cgaggagggc
     6661 gtcgtggata cggcgggcgg tgccggtctt ccgccaggtc ggccggacgc cgatctcctt
     6721 gagggccacg gcagggcgct cggtgtactt ctcggccggc gtcggggtgg tgcgctgcca
     6781 gtagcggtcg ccgtgttcga tggtgttgcc gtaggcgtaa ccgaccgggt gcccgtccgc
     6841 gtacgcgagg acggctgtga accccggctc ggtgctgtgt cggtccaggc gttcgccgaa
     6901 cgcggtgacg gcgtagttcg gcaggtggag gagcggggcg cgcacgtctg cgtacacgtc
     6961 gaggaggtca ccgcgggctg tgtcgagggt ggtgaaggtg cgcagttcga tggagggcgc
     7021 cgtggtcatg cggccatcct ccaggcggcg gtgtgctcgg tccaggtctg cacggtggag
     7081 ctgccaggcg cggtggcgcg cagtgcggcc ccgaactcct gcagcatgcg cgtgacccgg
     7141 gcgtgctggg tggcggcttc ggcggggact ttcatcgcgg tggccgtagc agcgtcgggg
     7201 gcgccctggg cgagctgggc gtgggcgagc cgggtggtgg tgatggcgcg ggaccggatc
     7261 atgtggggtc ggagggcgga caggcagcgg tgggcgtggt actcggcggt cgagtagtcg
     7321 ccgagcgcca agtgtgcgga gagggccagg gagtccagtt cggcctggtc gtagaaggcg
     7381 agcatccaca ccggccggta gtcggcgggg tcggcgcgca gcatggcgtc ctgcgcctgc
     7441 tcgaacgcgc ggcgggtgcc ggtgcggtcc tgtgccgtgc cgtggatggc cgcctggcgg
     7501 gccaggccga gggaggcgaa cagggggtcg cggcgggtga ggtgcaggtt gcgggcgacg
     7561 tcgttggcgg cgaacgcgtc ggcgggtcgg cccatgtggc ggtacatggt gccggcgtga
     7621 ctccagatgc ggaacttgat cgcctggtcg ccggacatct cggcgagggc ctgggcctcg
     7681 cgcatgtgcg ccttggcgac gtcgtagcgc cggccgtcga tggcggccca catcgcggag
     7741 gagcggaaag cggctgctga ggcgtagagg ttgctgcgta cgcgctgggt ggcgctgcct
     7801 gcgttctgga ggttgagcgc ctcgtcggcg agggcggcgg cccgctgttc gatgccgagt
     7861 tgtccgccat ggcggtggtc gctggcgatg atctcggcga agcgcttgtt gaggcggttg
     7921 acgtcgctca tgccgatacg gcgcggcgat gcggtgccgg gtgcggctgc tgctgcggca
     7981 gccgccgcga tgctgccgac gagggtgcgg cgcttcatgt cggggtcctc ctgctgcggt
     8041 ggggccgggg tggacgaagg ccggctccgt ggcacgaacc ctaaggcgat ggcgggtagt
     8101 ccggtgacgt cctcaagtgc cttgcgggcg gccgactttg gccacgtgac ccggcccgct
     8161 ttccatgccc ggaccgatga gccgtcgagt cctccaaggc gcccggtcaa ccgttcaatg
     8221 gccctgttca cggcctcggc gaggctgttg gagctgtagc cgtgctcggt catccacgcc
     8281 tcaagaacgg tgttgcgggt ggtgtccatg cgggcacggt agtccgcgcg atccccactc
     8341 gccaggtaaa ggggaggtca aaacgtccta ggtgggtccg tcggctgagt gcctgaacgt
     8401 cctaaccaac ctgctgcgaa agggagttgt ctgggtgctg gtcgcccgcc gcgccccacc
     8461 gtgcgggcgg ctgttgacgg cccggcccgc ccctgaggtt cccccgcggg ggtgggccgg
     8521 gcgccgagac gacacgaagg ctccacccca atgacgagtc tgaaaacacc agttgaggcc
     8581 ctctccgtcg gccaccccac gtacagccag accttcccgt gcaagccgtc cacggccgag
     8641 ctcggccgcg aactcgtccg ggacgtcctc ggcgtgtggc acctcgacgg cctcgccgac
     8701 cgtgccgcgc tgatcatcac cgagctcatc gcgaacgcct ccaggcacac tccgtgtccc
     8761 gagatccgcc tcacggttgg gcggccgagc gcgactcgac tgcgtgtcgg ggtcgtggac
     8821 cgggaaccat cgcgtcttcc catactcagc caggcggctg acgacgacga atcgggccgc
     8881 gggctgctcc tcgtcgatgc tgtcgccgac cgctggggct acgacctgca cggctcaggc
     8941 agacgccctt ggggcaaaga ggtctgggcg gaactccgca ccgggggcgg cgagtgagca
     9001 tccccgccac ggcaccctcg ccccttccgg acctcgcccg actccggccc cgccagcaga
     9061 tggccatgga ctgcgccctc tgtgcccggc cgctgggagc gagcggtcga cggctgggcg
     9121 agatacgcca ccggggcctg ccgttccagc tctgggcctg tgctcctgac tgccaggcca
     9181 ccagatcgac catcccgacc ggctgagaaa ggggacgtcc ttccatggag tggccgcgga
     9241 tcaccggtga ttgctggctc ggctgtgggc gtactggagt cctggtgatc tggctcggcc
     9301 cggtgcagtg ggacgggcag cacgccccct tctaccacat gcgagccgtg cctcgatcgt
     9361 ctcaaggccc aggcactcgc ctacttcatg gagcggcgac cggcatccgc ttgatcagac
     9421 tcccggcaca cgacttcccg gcgtgaggca ggcagcccgc gaggacttcc tacgcggggc
     9481 acgttgcctc ccgccgggcg gccaggagcc gtccggggag cagccgtctg gcaacgctcc
     9541 cgtgacggca cctggtgggc gctccagccc agtaacacca caacgattgc gaggagttgc
     9601 agcatgacgc gcagcaccgt agttcccagc cgcaccgaag tacgccccca gatccggggg
     9661 gcatcagacg gcttcgacct ggacgtctcc ctcgtcgaga tcgccgaccc ggcgggcctg
     9721 gtcaacctga ccgacgacaa ctgcgggtcc acctgcggcg cctgcaccac caacgtcgcc
     9781 tgacccggac cccagatcac cccggtctgg tgccgccgcg tctccgcgcg gcggcaccag
     9841 ccgcccgccc cctcacctac ggaggtactt ggtggttgct ccgcccgcag cgttccgcac
     9901 cggttccact gctctcgtgc gcgccgtggc ccggccctcg ctgccgtttc ctccatgtcc
     9961 tgacctcgat gaccgctcac ccagtggttc gtctgcccat gtggcgtggc tacgcgcggt
    10021 ctgggctgac acggacgtcg ccgaggcact ccagcactcc agcccggtcc tggccacgca
    10081 ggtaggagcc ctgtgcacgg ccgagtaccc cgccctccgg gatgtgcggc gcgcggtgct
    10141 gtccgtggcc cgctacctgc tgcggaccca gcaccgggcg acacccttcg gcctgttcgc
    10201 cggcgtggcc accgcggagt tcggcccgca ggcgcgggcc gactggggcg aggagcacgt
    10261 ggccgtcggc cgcgcgggag cagagtggct ggcggccctg gtcgcacggt tggagtcgtg
    10321 cccggacctc ctcgaacggc tgcccgtcgt catcaacaac accgtgacat accggggaga
    10381 ccggctcatc gtgccgttcc agcccgacgt ccaggacgac cggactcgcc cggtcgaggc
    10441 gtccctggcc ctgaccggac cggtgcacgc cgtcctcgct gcgacccgac tgccgatccg
    10501 gttcggcacc ctcgtggaca agctccaggc ggagttcccc gaggccggtc ccgagaaggc
    10561 gcgtcaactg ctggcagagt tgatccggcg gcgggtgctg atcacgggcc tgcacgctcc
    10621 gagcactgag accgacgccc ttgggtatct gctcggccaa ctcgacgcga tcgacgctgg
    10681 aacccttgcc ccggtggcgg agacggtgcg cgagctacgc gcggtccggg cgggcctgga
    10741 ggagtgtgcc acgcacggag gccgggacag cgtcgcggcg cggatgcgag acctcgtccc
    10801 tggtctgcgt cgccaccccg tcgcgctcga cctccgcctg gacgcccaga tcgttctacc
    10861 ggaagcggtc gcccgagaga tcgagcgctc cgctctcatc ctgacccact tgagtatccg
    10921 cccgtacggg accgccgcgt ggaacgcgta tcaccagcgg ttctacgagc ggtacggcat
    10981 cggcacgatg gtgccgctcg tggaggccgt ggcggacagc ggcaccggct atcccgacgg
    11041 ctacccaggc gcttcggcca gcgcacgcag gccccgcgtc tctgctcggg atgacgccct
    11101 cgtacggctg gctcaggccg ccgcgctcga cggccgtgac gaagtgatcc tcacggacga
    11161 acagatcgag gccctggatg cgggtcccga cgagcctcgg ctgccgccgc acttggagat
    11221 cggggtaagg gtgcacgcgg ccagcctgga ggagttgcag cgcgggcggt tccggctgga
    11281 ggtcgtgagc gtctcccgtg gtgtcggcgt ctccacaggc cgattcctca gcgtgctggc
    11341 ccccgccgac cgggaggccc tggtcgcaga gcttgccggc ctcccggccg cagacggcaa
    11401 caccgtgccc gcgcagctct ctttcccgcc cctgctcccc gagagcgccc acgtcacccg
    11461 ctccccacag gttctaccca ccgtgatcag ccttcaggag caccgcgccc cgcaggacac
    11521 cgtcctcacc ccggaggact tggccgtagg gtgtgatggc cgccgcatgt acctcgccgt
    11581 ccccgagcgg ggccaccgtg ttgaggccgt cggggtgcac gcgctgaacc tgcgcaccca
    11641 caccccgccg ctggtgcggt tcctcactga actgtcccgc gcccagtgcg cgcaggtcac
    11701 cgtcttcgac tggggcgccg cagcggcgat gccgttcctt ccacgtctgc ggtacggccg
    11761 gaccgtgctg gccccagcgc gctggcggct ggaagtgtcc gaactgcccg gccatgcccg
    11821 ccctcgggcc gagtgggacg ccgcgctcag cgactggcgt gcccggcgga ggctgccgcg
    11881 ccgcgtccat ctcgtcgagg acgaccggcg cctcttcctc gacctcgacg aggccggcca
    11941 ccgtgcgctc ctgcgcagac acctcgacca taggcgcctg gccgtactcg tcgaggcccc
    12001 ggaaccggag gcgtatggct ggtgcggcgg gcgagcccac gaggtcgtgg tgcccctcaa
    12061 agcgaccagg ccgtcggcat ggccgccact gcccgccccc agccgcgccc gtgccctgtc
    12121 tgcggctcag atgcagacgc ctgccgcttc ctcggttgtt cttgccgccc tgtacggcgc
    12181 ccctcgccgc caagacgtct tgctctcaca gcacttgccc ggcctcctcg aacaactcgg
    12241 taacccgccg tggtggttca tccgcttccg agacccggac caacacctcc gcgtacgcat
    12301 cgccctcccc gacccggaag ccttcgccga cacggcccga accgtgagcg cttgggccga
    12361 cgagctacga agcatcggcc tgctggccga cctgcgctat cccacctcct accgcgagat
    12421 gggccgctgg ggctccggca ccgcatggga ggcggctgag gaggtgttcc gggcggactc
    12481 gcgcgccatc ctggtccagc ttgcgcagcc acagcgcccc ggactgcgca cgctggtggt
    12541 ggcccacacc gtcgccatcg cctccgcgtt cctcggcagc accgcagccg ggatgcggtg
    12601 gctgattgac cacatcccgc cgacagcccc cgctcccgtt ccgcgcccgc agttcaccga
    12661 cgccgtacga ctcgccgacc cgagcgacga ctgggcggcg ctgcgccagg tcccgggcgg
    12721 ggacgccatt gtgtcgggat gggcagaccg agatgcggcg ctcgccgcgt accggccgca
    12781 cctgcccggc ccggacaccc agggcatcgc cgtcgacgac gtcctgacct ccctgctgca
    12841 cgttcacttc gtgcgccacg tcgccgtgaa cttcccggag gaagaggtgt gcctctacct
    12901 ggcgcgcgcc gccgccctgg cctggacggc ccgcacccgt gggagggcct cgtgaccacc
    12961 caccccgcgc tcggcctggt cgacgccatc gccgcccagc tcgccgaccc cgacaccgtg
    13021 ccccgcggct ccagggcgct gtcctcggac cggcagcacc ttgcctacgg cccgcccggc
    13081 atcgcgctcc tgcacatcga gctggccgcg aacggcctcg gcccgtggca ccgcgcccac
    13141 gactggctcg ccgccgcctc ccggcagccg ctcaccagcg gcccagccag tcaccccttc
    13201 tacggagtac ccgccttcgc ccacgccctg acctgtgcgg ccgaccacct tcccggctcc
    13261 taccaacgcg ccctcgacgc gatggacgcc cagatcgcag tcgacgtcgg acgccgtctc
    13321 gatgccgcac accgccgcat cgacgccgga cgcctgccgc agctcgccga gttcgacgcc
    13381 atccggggcc tcatcggata cggcgcctac ctactgcgcc gaaaccccgg cagctccacg
    13441 atgcgcgccg ttctcgacta ctgcgtgcgc ctcaccgaac cgatcaccca ccacggcgag
    13501 agcctgccgg gctggtgggc ggagaccggg ccctcaggca gcccggacga ccgattcccc
    13561 ggcggtcacg ccaacaccgg tatggcccac ggcatcggcg gcgtgcttgc actcctggcc
    13621 ctcgccgctc ggaaccgctc cgtcaccgat gggcaccatg cagcactgcg caccatcctg
    13681 gcctggctgg accgctggaa ggagaagacc agcggcggac cggtctggcc gtactgggtc
    13741 actcaggggg agctgcgcag cgggcgtccc ggctcgtcag cccccaggcg gccctcctgg
    13801 tgctacggca ccgccggcct cgcccgcgcc cagcaacttg ccgcgctggc cctcggcgat
    13861 gcgagccgcc agatcgccgc ggagaacgcg ctcgtggccg ccctcactga tcccgagcag
    13921 ctgaaggcca cgacggacaa cggcctctgc cacggcttct ccggcctcgc ccacgctgcc
    13981 gcacgcacgg ccgacgacgc ccacccctcg accgctggga aactccgcgc cgcgatcccg
    14041 accctcctgg ctgcggtcat cccaccgggc accgaccccg aactcatggc cacggcgctc
    14101 atccaggacg aggaaggcgg ccccggccta ctcgacggcg ccgccggcat agccctggcc
    14161 ctcctcgcgc ccagcaccgc cgcaccacac cggtccgcct gggacgcatg cctcctcatc
    14221 gcttgatcca ccgaccgaag gacctctatg cctcccgacc gctggcagca gcacaacatc
    14281 accttcgtcg accgcgagat tgcccagcgc accatcgccg aacgcctcgg ccccaccctg
    14341 atcgaggcgg aggccgacgg gcagctcacc gactggtggt tcatgaacaa gcagccctgg
    14401 ccgctgcgtt acctcgcgga caagccctca ccagccattg agtcgctcct gagcgatctc
    14461 gtccgcgaca gcgtggccgt gtcgtgcctg ccctgcgtct acgagcccga gaccgacacg
    14521 ttcggcggcc cggaggccat ggacacagcc cacgaactgt tccacagcga ctcgcgccac
    14581 ctgctcacct accagctgag cccgatgcat ttgggacgtc gggagaccgc cgtcctgctg
    14641 gcgagcgtca tgatgcgcgg tgctggactc gactggttcg agcagggcga tgtatgggcg
    14701 aaggtcgcgg cccttcgccc ggccaccgct ccacaaccac ctgaacgaac cgccgaactg
    14761 actccggcca tgcggaagct catgaccgcc gacgcccacc gcctctgccg cccgggtagc
    14821 ccactccacg cgcacgagga atgggtgacc gccttcgaac gggccggcgc cacgctcgct
    14881 gacctcgcag cccgcggcgc cctcacccgc ggcctgcgag ccgtcatcgc ccaccacgtg
    14941 atcttccacg ccaaccgcgc cggtctcctc cgggacgacc agagcgccct gtcccacatc
    15001 gcacgagagg tagtcatggg aacgagtgac cacaccgagt cgcccaccga ggcaacggcc
    15061 gagatcgata gcgtcagcgc ggtgaacccc gacacgatcg ccacccccac ggcggacgcc
    15121 gagcgtctcc gcaacgccct ggtcgaccag ctccgcgcgg acgggcatgc ccgcacgccc
    15181 gccgtcgaga ccgcgttgcg gaccgtcccc cgccatgtgt tcgtgcccga cgcgtccctc
    15241 gaagacgcct acgccaacgc accggtgcac atcaaatacg acacccacgg cacatcgatc
    15301 tcctgcgcct cccagccggg cgtcgtcgcc ctcatgctgg atcagctcga cgcccagccc
    15361 gggcagcgcg tcctcgaact cggcgccggc actggctaca acgccggtct gctcgcccac
    15421 ctggtcggcg agagcggaca cgtgaccacc ctcgacgtcg acgacgacct cgtggagggc
    15481 gcccgcgcgc acctcgccgc cgccgggatc accaacgccg aggccgtgac ccgtgacgga
    15541 gccctcggct acgccgaggg agcgccgtac gaccggatca tcgccaccgt gggcgcgcac
    15601 ggcgtaccgc acgcctggct gcagcagctc gcccccggcg gccggctcct tgtcccccag
    15661 cgcctgaagg gcaccgtctc ccgttccatc gcctacgagc agcgcgatgg ccgatgggtg
    15721 tccctcggca gcgagatgaa caccttcatg ccgcttcgga ggggcatcgc cgacgacgac
    15781 cgccgagtga tcccgctcag cacggacggc accgtacgac tccaggcccc cgccggactc
    15841 aacatcgacg ccgacgccct cgcaggtgta ctcgaccagc cgcgcaccga ggagtggacc
    15901 ggcatgacgg tccgcgccat ggaatcgccg gagtggatgg aactgttcct cacctgctcc
    15961 ctctcctccg gcctaatccg gatgctgttc cctcagagcg ccaagggcac tctgctcacc
    16021 gaggatccct acccctcgtc gaccgccgtc gtcgaccagg gcgccgtcac ctacctggcg
    16081 cggcggctgt cggagaagag gacccccgag ggcggcaagc tctgggagtt cggcgtcatc
    16141 ggccacggtc ccggcagcga cgaactggcc gcgaaggtcg ccgacgccat ccgcacctgg
    16201 gaccgcgaat accgcagccg tgaggccacg ttcgaaatcc agcccctcga cgcccccagc
    16261 atcgagcggc gccccggcct cttcgctctc gacaccccgc tgaaccgcat tgtcgtcgac
    16321 tggcagtgac gccccacgcg tagcggacgg tgcccgtcga cacatggctg gcgggcaccg
    16381 ccgcctcagc attcctcact ctcgacaagg gggatccatg gacccacacg gctccacagc
    16441 ccagcgcttc ccgctcgtcg cccgattccg acccgcctgc ctgcccctgc ctgaacgcgt
    16501 acgcgcactc gtcgacctgg ccgacaccgc ggtgaaagag actgaccagg ggctcgcatc
    16561 agccgtctac aaccaggccg cgctcatcgc ctccgacctc ggcctccccg acctcgcccg
    16621 cgagatgtgc caccagcacg ccgccgccta ccttcacgcc tgccccctgc ccggcatgag
    16681 cgcgatccga ggactggaac cggtcgtcaa cctcgctcgc ctccagatcc gcgccggtca
    16741 cgccgatgag ggtcggcagc gactcctcaa cctgtacaag gccgtcgagg cgggcgcagc
    16801 cgcccggttc gagcgcgtca ccgtacccgc gagcctcact gcgaccggcg aagaccgcca
    16861 ggaggttcgc gcgtggctgt ggcgcgtcct cctcgcagac ggcacgcgca ccctcaccac
    16921 cgaggggcaa tgggccgaag cgctggcgca catcgaagcc caccatggca tcggaaagcg
    16981 gatgctcgac ggtcggcagg tcgccgtcct cgccgctctc gttgcgggtg acaccgcgtg
    17041 ggccgctgcc ctccttgccg acacgatgcc cggcggccca tgggaacaag ccgtcacgac
    17101 atgcctgacc gtcctatgcc gccgcgacgc cgggcagccg atcgacgggc acctggcgga
    17161 cctggtgacg gtctactccc gacggaagac cgaacccggg tgatcgtatt cgacacccgg
    17221 ctcggactta cggccctcga cgcgatcggt tccgccgagg cgctcgccgc gcaccgcatc
    17281 gtcgaggacc tccaccgcag gacgacagac gccgaagacg gctatgcggc tcgcgagagc
    17341 ttggctcatc ctctgttcac cgagaccgcc acggaccggc aagggcagga ctgtcgcgcg
    17401 ctggtacgcg cctgcgccct tggctcaggg accctcccga acgagctgcg aggagaactg
    17461 acggcggctc tgcgcgccag cgaccgcgtg atccgggaaa gcctcgcacg tccctccgat
    17521 cccggaggaa cgcaactcct gcggctctga cggtgtctaa cggcgccatc ggtgctgctg
    17581 ctcggcaggc gtcgtcgccg ccgacggaag ctgaccgtta tggatctgct ggacgcggac
    17641 cgagggtgtg atggtcgagc gtcggcgggc agcttcagcg cggcggttcg gggccgggtt
    17701 ccggccggtg tgctgaatac gggtgatcag cactcgggcc ggttggcggg cgctggtcaa
    17761 ctcgcgctgg acagcggcct ccttgaggag ctggtggggt tgatggccac gggcttcggc
    17821 gtcggcaagg acggtggcga gcgcgggcca ggccgggtcg gcgaggatgc gctcggcgtg
    17881 gtcggggacg gctgctcgta cgtcgttcgc gaaaacgcgg cgcgtttgct ccctgggcgg
    17941 tcgggctgtg agttcggcga gagtcggagc aagggcacgg tcggcggccg tctggaggtg
    18001 ctggacggcc tggccggcgg cgtcagcctg gtgggcgtgg tgcttcgctt cgtgccagcg
    18061 cctggcgacg atggtggccc agacgagggc tgcgaccatg gctgccagtg cgctgccgtc
    18121 ggggccggtg gcggtgtgga cgatgtcgcg ggccgcgctg cgcagggcgt gggcggcgcg
    18181 gtcttcggct cggatctggg agcgctgggc tcgggcgaac gccttggcgg cggcctggag
    18241 ttcggtgcgc aggttggcgg gtaccttctg ggcggtagct tcgagcagtt caccgagggc
    18301 ggtgatgtgg gcctgggcgt gtgtgtcggc ggcgaggtcg ctgtggaggg tgtcaagggc
    18361 gtcggtcgct tggcgccagg gggtgctggg gtggttgcgg cgggcggtgg ggtgttcttc
    18421 ggggcggctg gattcgagac gggccttgat cttgggcagg gagaggtcgg gggagatctt
    18481 gcttccgggg tggtagatct gctcgccggc ctcgttgacg tcgccaggtc ggccggcggc
    18541 gtagccgagg aggtcgcctg acgggccgcg ccggacctgg acctcgacgc cgctggcttc
    18601 gaggtaggcg atgaattccc cggcgttggt cacgtgcggg atggcggcgc ggatgcgggc
    18661 ctggagccac tcagggctgg gctgttccca gccgaggcgt tcggccttgt gcatctcggc
    18721 ctgggtgggg cggcgggtgc cggtgcggtc gcccttcttt aggcggcgca gcccgtagtc
    18781 cttctcggcc tcgcggcagg cgtcgccgac gcggatgccg ctgtcgtgga gcttggggcg
    18841 gcgtccgtct tcgcggacgg tggtggccag gatgtggatg tggtcgtcgg cgtggcgtac
    18901 ggcgatccag cggcaggcca ggtcgtcacc ggccggagcg atgccggccg cctggacgat
    18961 gcgctgggcg atgtcgcccc actcggtgtc ggagagatag cggtcctcgg gggcggcgcg
    19021 cacagggcag tgccagacgt ggtcggtgac cttcccgccg aactcgctgt tgcgcagccg
    19081 cacgggctgg tcgaggtagc gggcgagttc ggtgagggtg gcgttctcgt ctcggccggg
    19141 gtcgggcatg ccgagcatcg cgaatcccgc gacgatgtgc gggtcgaggt gctcgtcgtg
    19201 gtcgccgggg ccgtagaggt aggcgagcag gccgcgggtg ttggacccgg ccggtttgat
    19261 ggcggcgatc acgcggctga ctccgtcccc ggatcggtgg gctggcacag agcttcggcg
    19321 atcagctcca gcaggtcgtg gagttcggtc aggcgctggc ggatgtcggg tggggtgcgg
    19381 tcgctgttga gagcgcgggc gatctggttg acgttcaccc cgatccggtt gagctggcgc
    19441 agcacctggg ctcggaagat gtgcgtgcga cggcggtcct ccgacagggg caggttggca
    19501 gtgaaccggc cggtgatgaa ggcgaggacg atgtcggcgg cgaacccgga gtcgcccttg
    19561 tagccgtgct cggcggcggc ctcctggagc tgggtgtgct cgtcgccggt gaagcgcaag
    19621 gggccgacgc ggacgacgcg tttggtgccg gtgaagcggc ggatcgtggg ctggacgctc
    19681 ttcacgacgg gctcaccgcc aacgctctcg gcggtgtcgg tggcgcgtac ggggcgcagg
    19741 gtctcgcgct ggacggtgtg gagcgtgtcc tcgtcggggc cgccctcggc cccgacgtgc
    19801 tggcctggcg ctccctggcg ctgggccatc tccgccaccc ccggggcgga gatccccgat
    19861 gcccggccgt gagtcggact cggggtacta ctggctccgc caggggcagg tcgtccgaac
    19921 gcgcggcgcc aacggtccag cagcgtaggg ggcttcgtca gcgggagcgg ctcgtcgggg
    19981 gtgttctcgg ggtggggcgg gtcgtgcgtc atggacggtt ctccggagaa agggtgggag
    20041 ggcgtgcggg tcaccgcgga gatcagatgg agttcgggcg gctgccgcct cgtccacagg
    20101 tgtggacgct cgcgcgctgc gcggggcggt ggccggcggg ccgggtgacc ggaagggttc
    20161 cggtcacccg gcagcggttg cggtcagccg ccgtcccgat cggtctcggc tggggcttcg
    20221 agttcggccc ggaggatgtc catcacctcg gtcagccgct tgctgccgat cgtcagccct
    20281 ttggcctcaa ccgccgttcg gacgacgacc cgggtgagct tgccctgctc agcggccgca
    20341 gcccggccga tctccacgag tacctcaagc ggggcgccgg gcggacggcc accgcgcggc
    20401 ttgccctccg cagcctggga aggcgattcc ggcgactggc cggatacagc gatcggcagc
    20461 ccagtgatcc gaccgggctg aaccactagg tcggcaggcc gaacgccctc ggccggagcc
    20521 tcggcagacg ggccaaccgc ggtggccggc gccttggcgg ggtggacgga tgtggtggcc
    20581 ggtagttgcg gcacgtgcgc tgaatcgggg tccggatggc cggcagcagg ctgtgtgacg
    20641 agttcgtgga tctgccgcat caacacgccg aaggccacca tcgcggcggc cgggggaacc
    20701 gcggcgacca cgtagtcgag caacggcacg ctaccgatgt cgcgagtgcc ggtcaccccg
    20761 gccacgttga gcccgatgga gccgactgaa ccgatggcgg tgacgccgat ggcccatttg
    20821 tccttgacgc ggcgcaggcc cgcacggagc atgagcagct cgcccgcgac gatgaacgcg
    20881 tccagcgtcg cgggccacgc ccatcggcgg gtcggcgagt cacggagtcc atgctgggcg
    20941 gcgacgtccg ccaggtgcgc atacgagagc cagaacgcac ccgcggtcag ggccacgatg
    21001 acgacgccgg ccatacggag cacgtactgc tccacggtga gcttcgtctt cgccggctgc
    21061 tccaggccgg gctggtcgcc ccgcagcggg cgttgtcggt gacgggacac gagagggatc
    21121 ctcaagcggg gttctcctgg ggtagtagtg gggtgcgtct ttgccgtctt gaccgttgca
    21181 ggcacaggtc agagcaggta cggcaaccgc ctctgccatc cgtcctggcg ggtgccgccg
    21241 acgccgtgtt ccgagccgga acacgacatc ggggcgtcct ggcgggcctg acccggggtg
    21301 gaccgtgtcc cgattcggga cagaggcgtt gcgtcttccg tcccggaggg cagagctgtg
    21361 acctgcggcg atacggcagg acggcgcggg acggcgcaag acggatgcgg gcagcgtctt
    21421 gacggcaggc tgcgattacg gatcgctgtg ccgtcttagc ctcggttccc gtcttggctg
    21481 catgccgttt gacctgcgag atcacggcag ggacggcaag tacggcaaca agaggagcag
    21541 gggttcagcc tgcgtcgaga ccgccgggcg gggcgttcac tcagtgaacg gcaggtggtt
    21601 caccaggcgg agccgcctga gtgtccaccg ggtggacggt ggggcagtac cggcgccagg
    21661 catcgaggaa cttgttgcgc atgtagccct tgcgctgggt ccggtcggcc atgcgcacgt
    21721 tgccggattt gatctcgtac gtgcgcagca tcctgctcag ctcacgcgcg gccagtccgc
    21781 cgcgtcccca ctccgcccac ggagcctcgg ggtcctggcg caggtggtgg aggagttcct
    21841 cggtggacag gctgtccacc tcgcgctggg agtagaagac ccggcggatg tcggcgagga
    21901 tccgcgcacc actggggtgg tcctcctcgg ccgcctcttc ggcggcgacc atccgcacac
    21961 aggcgacccg cgccagccgg ggccaacgtc caccggccag gtcggcgacg atgaccagag
    22021 gctcccaggt gtcggcggcg cggtcctcga ccggcatgtc cggctccagg ttcgcggcct
    22081 cgtccagcag cggcctggcc cacgcggcga tgcggtcgcg cagatcatgc agggccggga
    22141 tgtcgcgacg ggagcggaag ggcttgacct tctcgccctc ggccctccgc cgcatgcgga
    22201 tcacgatggc ccggtccatc accgtgtcgg gcaggtcacc gatccccgca atggccgcca
    22261 tggcgaaggt agcgaagcgg tgcggggtgt ggtcgttgcc gacgacccgg gtgacgtacc
    22321 ggttgcgttg gtggccggcg ttgagcaggc cacgcatctc ctcattcttc tcggccatct
    22381 tcggggtgcc gaagatggtg tcggcctcgt ccaccaggag tgtgggcggg ttctcctcgg
    22441 tgatcgaccg gaagatggcc gccggtgtgg tgttgatggt gagcatcggt tcgtggaccg
    22501 tctcggtcag cacatccagc agccgcgact tgccgcaccg cttcgccggc cccaccaccg
    22561 ccaggcgtgg ggcgtgctgc caggcaggct gcaagtgcgt cgccgccacc cacaaggtga
    22621 tcgcgtccag ggcttcctgc gagggcggga tcacgaactg ggcgatctgc gcacgcagtt
    22681 catccagcag cttcgagccg tgggtcggct ccgcatcggg tatcgcatcc gggccgctcg
    22741 gcgtctccgc ctcgtcggcg ctacgggcgt ccgcatcgcc gctgaggtcc ggatcggcgt
    22801 cgtcagcctg cgtggcacgc aggtgggcgc cgggccggcc ggggacggcg gttgcgggcc
    22861 aggttgcctt ggcgggggcg gaataggact cggggttctc gggttgcact cggcagctcc
    22921 tcgtctggcg gtggcgggct cgcacgccct tgccgccggg ttggttcttc cagggccgtt
    22981 cgggggtgct cgggcctccg gcgttgcacc gccggaggcc cacccctttc tcgcgggcgc
    23041 caggccatcg cgagggaaca cggaccgtac gtccacaccc ggcagcagtc cagcgtttct
    23101 gtgtcagctc agcgcagaac gggctgctat gactccccgc tctcacgcgg ccaggcccgg
    23161 cagagccagc aggtcggcgg tcaccacccg gtaggcgttg cccagccgca gcaccttgca
    23221 cgggtactgg ccgcgcttcg ccagctcgta ccccttgctc cgcccgagcc ccagcgcccg
    23281 attacccgtc tccaggtcaa cggcggcggg aagctccagc agctcctctc gactcatgcc
    23341 cttcactcgg ccggcgagtt cgttctcgcg catacgcgct ccatccatga ctgagccctc
    23401 ggcgaacacg gcaatcgcgc tcgtctccaa gccatggaat caacgttagg gaagttaatg
    23461 tgtcctcatg acacaacacg gttgggatgc tggaggggac gaggacgacg tcccggagtg
    23521 ggtggaccag gtgatggcaa ccgtggccgc cgaagtccgc agacgaagga aggagctagg
    23581 gatgagcgcc caggacctgg cggaccgctg tgaggagatc gggcacccga tcccgcgcaa
    23641 cgtgatcgcc aacatggaat ccggccgccg agccaacctg cccctggtcg acgtcatcgt
    23701 cctcgccgaa gccctgcgga cctacccgat ctgcctgctc taccccgtcg gctacgtcga
    23761 ccgagtccag cgccttcccc ttcagcactc cgaaccggcc tgggatgcca tgcgctggtt
    23821 caccggtgac agcgaggact tcggcttgga agacgacatg ctccgttcct tccgtgccca
    23881 cgtccgccac cagcgcgccg ccctggccgc cctgaagggc gagaagcacg agcgctggaa
    23941 ggccgagacg gcacccaacc gggcagaacg cgaggaagcc gtactcgccc aagccgacta
    24001 cgcagaaagg gcgttggaag ccaagtatcg gctccgcagt gcccgcgcct tcatccgcga
    24061 agacggcggc accccaccgc acctgccacc ggaactcgcc gacgtcgacc cacccgagac
    24121 cgaccccagt accaccgagg agaacgatct ttgaagggtt ccacccaccg ccgctgctgc
    24181 tgccgcgacc cccacaccgg caagccgctc ggcaagaagt gccccaagct ctccagccgc
    24241 aagcacggct cgtactccat acgccaggaa ctcccgcccc gcgaagacgg cacccgccgt
    24301 tccttcagcc gcgccggcta cgagtccctc aaggacgcgc aggccgacct cgaccacgtc
    24361 cgctccctgc tcgccctggc ggagaaggac gaccccgaca gtcttcagcg cctcgtcgac
    24421 atgctggagg aggtcgcggt cgagaaggct ccactcccgg ccatcgagga gacccgacgc
    24481 cgcctaaggg cgggcctggc cctccgtggc agcctcaccg tcggtgagtg gctcgaccag
    24541 tggttcgccg cgaagaagcg ccgcaagacc acgctcaacg gttacgcctc ccacatccgc
    24601 gtccatctga agccgcgcat cggccacgta cgcctcgacc gcctcaacgt cggccacttg
    24661 gtggagatgt tcgacgggat cgccgacgac aacgaggtca tcgcggccga gaacgaggcc
    24721 cgccgcgagc agatcgcccg ctgcaagccg agtaagcccg gccgccccgt aggagctgag
    24781 cagaagctgc tcgcgatcga gcgggccaag ctggcggaga tgaagccgtt ccggaagatc
    24841 accggcccgg catcccgtca ggcgatacgc cgaaccttgc gcgcggccct gaactccgcg
    24901 atcgcccagc agctcattac cttcaacccg gcgtcccatg tcgagttgga gtccggcaag
    24961 cgcccgaagc cacttctctg gaccgatgag cgagtccgac gctggcgcgc gacgggcgag
    25021 atccccggcc cggtgatggt gtggaccccg cagcagttcg gcgccttcct cgacgcagcc
    25081 gagggcgacc gcctgtacgc gatcttccac ctcatgggta cccgcggcct ccgtcgcggc
    25141 gaggcggtcg gccaggactg gcacgagatc gacctcgacg ccggcctcat cacgcctgcc
    25201 aaggagatcg tggtggatgg ctgggatccc tacgaatccg agcccaagac ggacggcagc
    25261 gccaacacga tcgcgctcga cagcacgacc atcatggagt tgcgcgatca caaagtccgc
    25321 caggagaagg agcgcgcgca gtggggcgac gcctggcagg acacgggcaa ggtcttcacc
    25381 aaggaggacg gctcctggct ccacccggag accgtctccg agactttccg ccgcatcctt
    25441 gccacgaccg acctgccgcc catcaccctg cgggacctac gccacgtcgc cgcgacgctc
    25501 acgcacggag gtggcggcga catccacgcg gtaaaggaaa ccctgcggca ctccaccatc
    25561 gcgctgacct cggacacgta cacgagcctg ctccccgagt tggaccggga gatcgccgaa
    25621 gcggcggcac gtctcatacc tcgtgctcgt cagcctcggt gaaaatgcca gcacgtcacg
    25681 cctcgaccga ccgcatgatg ttcacatgaa ggatgaaggt gccgagcgag tcgtgctgtt
    25741 cacgctggat cgggtaaccg agtgcctcgt tcttacgaga tctgatcgta aagaagcgcg
    25801 aatcccgctg cagcatcctc cgtttgagga cagcagcgcg ctcgccaggc tgcaccttgc
    25861 agcagagacc cttgatgctg tggtggctga aacgctccgc ggagactcga tctacttcga
    25921 gcttcctaca gcaacccgtg ttgaaccgct cgatggtcgc ctcatcgtgt acctcgacca
    25981 aaacaagtgg agcgagatca gtaacgctct gcactcaccg gaaaaggtca gctccgagaa
    26041 ccgtcgggca tctgcacagc tactccaatg ggtgcaggac aggctcatcg tgttgccggc
    26101 atccgccggc cattacgccg agacaggcaa gaggttcagc accgagaagc gctacgacct
    26161 cgccctgacc atcctgcagc acagtcgtgg ctggcagatg cgagatccgc tccaggtcag
    26221 gcgcgaagag attcaagatg ctctgtcccg gcacactgac gccgaaagta cacgtcaggc
    26281 acccaacgta ttcaccctca cccccgactc tctgtacggc gcagcacgt
//
