LOCUS       NZ_KQ947984            21203 bp    DNA     linear   CON 21-APR-2024
DEFINITION  Streptomyces curacoi strain DSM 40107 PRJNA299217_s001, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ947984
VERSION     NZ_KQ947984.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces curacoi
  ORGANISM  Streptomyces curacoi
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1266825)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Draft genome sequence of Streptomyces curacoi DSM 40107, type strain
            for the species Streptomyces curacoi
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1266825)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-OCT-2015) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 13-OCT-2014
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 65.7x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001513975.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 02:05:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,531
            CDSs (total)                      :: 7,455
            Genes (coding)                    :: 7,251
            CDSs (with protein)               :: 7,251
            Genes (RNA)                       :: 76
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 204
            CDSs (without protein)            :: 204
            Pseudo Genes (ambiguous residues) :: 0 of 204
            Pseudo Genes (frameshifted)       :: 91 of 204
            Pseudo Genes (incomplete)         :: 154 of 204
            Pseudo Genes (internal stop)      :: 21 of 204
            Pseudo Genes (multiple problems)  :: 54 of 204
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:06:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 914494
            Orig. end                         :: 935697
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ947984.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21203
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21203
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21203
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11203](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11203
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            348..800
                     /locus_tag="AQI70_RS04070"
                     /old_locus_tag="AQI70_04060"
     CDS             348..800
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115019.1"
                     /locus_tag="AQI70_RS04070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04060"
                     /product="hypothetical protein"
                     /protein_id="WP_244181438.1"
                     /transl_table=11
                     /translation="MGSWGTLGPAVLSLAGVALGAAGSLFGQYLVSRASHRQLETQQNA
                     EHRAEVKDVILKFLEVAFRVEKAASAVPDGEEPPEALLDELWLAQAELDLAARTEPLRG
                     AAHRYAVRLTSAARGEGADGDGLYRAKVAFMDAAYDDLWPSSPRSR"
     gene            complement(748..1179)
                     /locus_tag="AQI70_RS04075"
                     /old_locus_tag="AQI70_04065"
     CDS             complement(748..1179)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001472.1"
                     /locus_tag="AQI70_RS04075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04065"
                     /product="gamma-glutamylcyclotransferase family protein"
                     /protein_id="WP_062144176.1"
                     /transl_table=11
                     /translation="MTLPFFVYGTLRPGEPNHDRFLRGRTAREEPARMTGLVLYDGPGY
                     PYAVEEPGSVVSGELVTARPEAYDELLDALDRLEDYAPGDPHNLYERVVREAVRQSDGT
                     PVPAWVYIAAFGVAARLRTRGPVIASGDWTATDRRTRHP"
     gene            complement(1280..1576)
                     /locus_tag="AQI70_RS38945"
     CDS             complement(1280..1576)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AQI70_RS38945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="5'-nucleotidase"
                     /protein_id="WP_159042605.1"
                     /transl_table=11
                     /translation="MRKTIGRLTVVLVAGAAGVVLTAGSAAAGSEWSAAPAGSEWGAAP
                     AGSDWGAVPVGSDWGAAPAGTDWGVAPASTEWGVAPAGNRWSTEATCLPRECR"
     gene            1830..3476
                     /locus_tag="AQI70_RS04080"
                     /old_locus_tag="AQI70_04070"
     CDS             1830..3476
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001471.1"
                     /locus_tag="AQI70_RS04080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04070"
                     /product="M4 family metallopeptidase"
                     /protein_id="WP_062144179.1"
                     /transl_table=11
                     /translation="MSRIRLHVRGSRLATAGAVTATATLLAAALSPAADADDRPTRAGA
                     IENAAEVLADRAESLGLTTAQDTAVRDVIVDADGTQHVRYDRTYRQLPVLGGDFVVHLA
                     KDGTYRGASRATTRPISLSSIAPSVSAPKAADLAANALRAANLGETLKKLTARPKLVVD
                     ALHGAPKLAWRTDVVAQDSLGNPAARTVLTDARTGAQIDAWDSIETATGDGKSLYGGTV
                     PLETTVSGSTYQLKDPTRGGTYTGDAANRTDLCVLAVCLNRAPATVFTDADNHWGTGTT
                     AERSTAAVDAQYGTDVTWDYYEDVHGRRGIAGDGKGSFNRVHYGKGYNNAFWDDSCFCM
                     TYGDGDGTQLGPLVSLDVAGHEMTHGVTSKTAALTYSGESGGLNEATSDIFGTLVEFHA
                     GNASDPGDYLIGEKIVRPGFGRSALRYMDKPSKDGSSVDCWSATTAALDVHYSSGVGNH
                     FAYLLAEGSGPKTVNGVSYNSPTCDGSSVTGIGRAKLGKIWYRALTVYMTSSTNYAGAR
                     TATLNAAKDLYGAGSVEYGAVAAAWKAVKVG"
     gene            3743..4666
                     /locus_tag="AQI70_RS04085"
                     /old_locus_tag="AQI70_04075"
     CDS             3743..4666
                     /EC_number="2.7.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001470.1"
                     /locus_tag="AQI70_RS04085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04075"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_062144182.1"
                     /sec_met_domain="APH (E-value: 9.8e-37, bitscore: 123.2,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPSPTKMHAEELDIDETLVARLVAEQFPRWAGLPVTRVASAGTDN
                     AMYRLGADLVVRLPRLPGGSRQIETEHRWLPHLAPHLPLAVPTPLALGEPAAGYELPWG
                     VYDWLDGENAYDAPLGEPREAAGELGRFVAALRKVDAAGGPLSFRGDPVGKHDAYVRTA
                     IRDLGAVGMLDPAVATAAWEETLRLPQWDDAPVWLHSDLLPGNLLTSSGRLTAVIDFGC
                     LGVGDPAADTIAAWAVFDAATREVFRDAADVDDTTWARGRGWALCFGLMAEHHYGESCG
                     NGTNPVLAGVARRTVGEVLAEYSGGA"
     misc_feature    complement(4709..4727)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            4768..5520
                     /locus_tag="AQI70_RS04090"
                     /old_locus_tag="AQI70_04080"
     CDS             4768..5520
                     /codon_start=1
                     /gene_functions="resistance (resist) ClassA"
                     /gene_kind="resistance"
                     /inference="COORDINATES: protein motif:HMM:NF024748.4"
                     /locus_tag="AQI70_RS04090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04080"
                     /product="serine hydrolase"
                     /protein_id="WP_062144185.1"
                     /transl_table=11
                     /translation="MDIDGRVDAFVGNAPSRAVLLRSLRGRDVCVRRNADRVFPAASLM
                     KVPLAIAVLEQLDATRVVRRSELGRTAYPSVLEVFDERHEFTLVELCGLMLATSDNPIG
                     TFLVELVGMEAVTATAERAGAHHTHMRVGFSDRDLGAAARSSTTTADDMALILRYAATQ
                     AHLRPVLGALRNSVRNFRLPLRLPDDLKVAHKTGSLRRLAHDAGILFGRHHDLIAVFLT
                     EDQADTAAVGIQIGDCMADVWRLLGEPV"
     gene            5544..6530
                     /locus_tag="AQI70_RS38330"
                     /old_locus_tag="AQI70_04085"
     CDS             5544..6530
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AQI70_RS38330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AQI70_04085"
                     /product="hypothetical protein"
                     /protein_id="WP_062144188.1"
                     /transl_table=11
                     /translation="MSDQRRVIAEVRRTVRIYNLLVLVVGAIALVVSVDRAQDDVLVTS
                     LEVVGTTLVSAALVSFIFGQITIRDTTLQVNEAIDQALREVLEPIRENLFAGALSHYRW
                     DCHLDGLEPDGYAVQAMRVSYQVQVIPRELRFICVSSLTDESFSRLAGDLRYVLRWQVD
                     EGLELTDPHCFHVSHVRVDGQQLDQPAPRPTTLRGSPAVEYRFQVSELRRHHGFHSVEF
                     HVVARKYLGTDREVRVQAYAFRSLLDAEYRLTVGESIGAEILNTQISGLSRIGAGGLIQ
                     HGRTYPDAFGRVAAYAIFTTPLQTGSNVVFTIDRGNPRRANRGGAAS"
     gene            6549..6872
                     /locus_tag="AQI70_RS04100"
                     /old_locus_tag="AQI70_04090"
     CDS             6549..6872
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AQI70_RS04100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AQI70_04090"
                     /product="hypothetical protein"
                     /protein_id="WP_062144190.1"
                     /transl_table=11
                     /translation="MSLNHVAGDPGRWTRATLTERLAVYEDLGIGFDGVFDDLAARGWL
                     TEDGGAMTLTEAGEAGRLRARERNLRVHRQLHEGVDTADFVTTVNVLRRMVANLGGNGD
                     LPE"
     gene            7282..7803
                     /locus_tag="AQI70_RS04105"
                     /old_locus_tag="AQI70_04095"
     CDS             7282..7803
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381868.1"
                     /locus_tag="AQI70_RS04105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04095"
                     /product="hypothetical protein"
                     /protein_id="WP_062144193.1"
                     /transl_table=11
                     /translation="MRRTARLLTGTALAVGAVGLGGMPAYGDDVGGLKVLPSSVVPGGQ
                     VTVNTASCGDGGSAEGDASAVGAGSFTLAPRTHEHDATGKFQVPPSAQPGTYEIVATCA
                     EGGRRVTGDLVVTLTAPREQVHPRGSVKTGVGGALGPDPVQTAAGVAALAVAAAGGTWL
                     LHRRARGDGI"
     gene            7922..8581
                     /locus_tag="AQI70_RS04110"
                     /old_locus_tag="AQI70_04100"
     CDS             7922..8581
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001466.1"
                     /locus_tag="AQI70_RS04110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04100"
                     /product="class F sortase"
                     /protein_id="WP_062144195.1"
                     /transl_table=11
                     /translation="MRSHRSVGNAAIATATALALCSGAWLLRNGAETHTPPQPSAAQAA
                     AQSGDTGRGDPHPRARRSAAPALPPSPPDRIRIPSIRVDAPLMGLGLTRTGSLDVPPAE
                     RRNLAGWYEAGTTPGETGTAIVAGHVDNADGPAVFYHLGALKKGSTIEVDRRDGGTALF
                     SVDAVEVYDAKDFPDKKVYGAAPRPELRVITCGGGYSRTTGYQGNVVVFAHLTGSR"
     gene            complement(8519..8908)
                     /locus_tag="AQI70_RS04115"
                     /old_locus_tag="AQI70_04105"
     CDS             complement(8519..8908)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028376.1"
                     /locus_tag="AQI70_RS04115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04105"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_062145062.1"
                     /transl_table=11
                     /translation="MAIGRRPGSYECGVDAAMDVIGGKWKVLILWALHVRPHRFGELRR
                     ELPGVTEKVLAAQLRELEADGIVHREEFDEVPPRVEYSLTPRGETLNTALEPLGEWGKR
                     NVLAPSPAAGEVREDHDVALIPGRP"
     gene            9014..9913
                     /locus_tag="AQI70_RS04120"
                     /old_locus_tag="AQI70_04110"
     CDS             9014..9913
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001465.1"
                     /locus_tag="AQI70_RS04120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04110"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_062144198.1"
                     /transl_table=11
                     /translation="MTDNATDKASSPTPVTLLGTGAMGTALARAWLAAGHPVTVWNRTP
                     ARAEALAVEGATVAASADAAVAANRLVVACLLDDDSLGEALATADLGGRDLVNLTTGTP
                     GEGRARAAWAEARGARFVDGGIMAVPPMIGSPDSGAFVFYSGSAALFEEHRDVLAVPAG
                     TAYVGADAGFAALHDVALLSAMYGMFGGIAHAFALIRREDIAPEDFAPLLVSWLTAMAP
                     AALESAGKLESGDYTRDVVSNLAMQVAGIPTFLRTADEQGVRPDMVRPYLDLMRRRLES
                     GPHADEDTTGVIDLLTAT"
     gene            10001..11203
                     /locus_tag="AQI70_RS04125"
                     /old_locus_tag="AQI70_04115"
     CDS             10001..11203
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001464.1"
                     /locus_tag="AQI70_RS04125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04115"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_244181439.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-26, bitscore:
                     89.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSDPDSSLSVDAAQVNSVVRHDAALLEDDLRAFLKSLTAAPDDG
                     SADGSAAVCATALHRSLHRSLYTPVSDALGSKVGQQALPPSAGAPGGTAPLRPSMVYWA
                     YRNYRGFPEGPGSEEASADLAVVRRAAVAVRVLLKAAVVLDDIQDGSAMRYGEPALHIT
                     HGVPVALNTGSWLITAALRHAADPGVVDSLIRGVGHGFTGQALDLATRSADTRADLLAA
                     PHEERVRFWESVAARKTGTLFRMPLDAALAALGVVEEERHALDGAMRRLGLASQLFNDL
                     TDVVPELGGAKTHQDFDGLGNRVFLELLDSPPRPPRPSDPDGLTGARLKSYVLGHPRLR
                     DTLLDLSAQAVEWKRSAKEAVRGVCRSARSAAYFDVTIERKGHLIDRLHETLRQRSGAT
                     G"
     misc_feature    complement(11353..11368)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.33"
                     /tool="antismash"
     gene            11405..12616
                     /locus_tag="AQI70_RS04130"
                     /old_locus_tag="AQI70_04120"
     CDS             11405..12616
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004001463.1"
                     /locus_tag="AQI70_RS04130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04120"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_062144201.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.3e-62, bitscore:
                     207.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSNTRVVVIGAGLAGVRLARRLGELGTPVTLVGDEEHRPYNRVL
                     LAEVLAGRYSPEVIALPAPAELTRGRVTGIDREARAVHLADGTEIAYDTLVLATGSNPV
                     LPPLRGLFTPDHVLPEGVHAFRTMDDCLGLSKAVRPGVRAVVIGGGLLGVSAARALAMR
                     GAQVVLAQQSERLMERQLDPAASKLVRRHLTELGVEVHTECRVRDVRCVGGAVRSVEMA
                     DGYALDADLVVLACGVRPRAGLAQAAGLDVRKGIVVDDELRTSDPHIRAIGDCTQHDGT
                     VYGLAAPALEQADVLAESLSGNAGARYTGTRSLTRLTLAGQTAFDLAAFGETEARPGDD
                     VVQLADATRGTYRKVVVRDDRLVGGVLVGELGTVGALARAWEGAEPLPDDGPLLHLLTN
                     DGGS"
     gene            12616..15210
                     /gene="nirB"
                     /locus_tag="AQI70_RS04135"
                     /old_locus_tag="AQI70_04125"
     CDS             12616..15210
                     /GO_function="GO:0008942 - nitrite reductase [NAD(P)H]
                     activity [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_process="GO:0042128 - nitrate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="nirB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136308.1"
                     /locus_tag="AQI70_RS04135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04125"
                     /product="nitrite reductase large subunit NirB"
                     /protein_id="WP_062144204.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.2e-48, bitscore:
                     160.5, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 1e-12, bitscore: 44.4,
                     seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATGANPTIVLVGHGMVGQRFLEALAERGLTATHRVVVLCEEPR
                     PAYDRVALTSYFSGKTPEDLSMTDMEFIKDHGIELHIGDPAETIDREARKVTARSGLVV
                     DYDVLVLATGSYPFVPPVPNKDATGCFVYRTIEDLLAIEEYARTKATSGAVVGGGLLGL
                     EAAGALKGLGVETHIVEFAPRLMPVQVDEGGGAALLRTIEDMGLTVHTGVGTQEIVTDA
                     EGAVTGMKLSDGSELATDMVVFSAGVRPRDQLARDCGLTVGERGGITVDEQCRTVSDPH
                     VFAIGECALAADGRVYGLVAPGYEQAETAAATIAEDEAEFTGADLSTKLKLLGVDVASF
                     GDAHGTAEDCLDVVYSDSRAGLYKKLVIGRDGTLLGGILVGDADAYGTLKAFTGSVPPV
                     SPESLVLPAGAGAPAQLGPSALPDDAVVCSCHNVTKGTIRGAVTDHQCTTVPEVKKCTK
                     AGTGCGSCVKVLGQLVTAELEASGVEVDKGLCGCFSQTREELYEIVLALRINTYQDLLD
                     RYGRENARGTDGCEICKPAVGSIIASLAPTIGASGYVLDGEQAALQDSNDHFLANIQKN
                     GSYSIVPRIPGGEITPEKLIVIGEVARDFGLYTKITGGQRIDLFGARVEQLPLIWARLV
                     DAGFESGHAYGKALRTVKSCVGQTWCRYGVQDSVRMAIDLELRYRGLRSPHKLKSAVSG
                     CQRECAEAQSKDFGVIATANGWNLYVGGNGGATPRHADLLAQDLSDAELIRLIDRFLMF
                     YIRTADRLERTSTWLERIPGGLDHVREVVVEDSLGICEELESLMAAHVANYRDEWAETI
                     NDPEKLARFVSFVNAPDTPDPVVGFVPERDQIKPALPLLTIGHRPLEGSAQR"
     gene            15207..15557
                     /gene="nirD"
                     /locus_tag="AQI70_RS04140"
                     /old_locus_tag="AQI70_04130"
     CDS             15207..15557
                     /GO_function="GO:0008942 - nitrite reductase [NAD(P)H]
                     activity [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nirD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381873.1"
                     /locus_tag="AQI70_RS04140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04130"
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="WP_062144207.1"
                     /transl_table=11
                     /translation="MTLAPETTDLKVQVRLDDDWLTVCDLTRLLPGRGVAALLPDGRQV
                     ALFRDRAGQLYAIDNRDPFGGAAVLSRGLTGTHQGRPFVASPLLKQRFDLETGQCLDDE
                     AVRVATYEIRTA"
     gene            15608..16192
                     /locus_tag="AQI70_RS04145"
                     /old_locus_tag="AQI70_04135"
     CDS             15608..16192
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825699.1"
                     /locus_tag="AQI70_RS04145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04135"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_062144210.1"
                     /transl_table=11
                     /translation="MARTKEFDPDAALQSALELFWQRGYEATSMSDLVEHLGVGRASLY
                     ATFGNKHELYLKALDRYERAGFTPIVRELSQPGPALPSVRSVVRRYATEAADERLRLNG
                     CLVTNTAAELAPHDRAAARQVERNWDQLETVLHSALVRAQAQGELPAGRDPLALARMLL
                     VLLQGLRVVGKASSDPARVRDAAEQALTLLD"
     misc_feature    complement(16244..16259)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.81"
                     /tool="antismash"
     gene            16264..17043
                     /locus_tag="AQI70_RS04150"
                     /old_locus_tag="AQI70_04140"
     CDS             16264..17043
                     /EC_number="1.1.1.47"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (13-174). E-value: 1.8e-14.
                     Score: 46.0. Matches aSDomain:
                     nrpspksdomains_AQI70_RS04150_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388437.1"
                     /locus_tag="AQI70_RS04150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04140"
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_062144213.1"
                     /sec_met_domain="adh_short (E-value: 1.2e-32, bitscore:
                     109.4, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAAHRTRFTDRTALVTGAGSGIGRAVALALATEGANVVVTGRR
                     REPLDETVALIEEAGGKALAVAADVSRAADVRSVVAAAVDRFGSLDVAVNNAGVFRGGD
                     PLADLPEEDWHTQLGINVTGVFLALQAEIRQMRTQPTGGAIVNIASVFGVHGRHPGTAA
                     YAATKAAVSVLTRGAALDHIGDGVRINAVSPGAVDTPMSLLPGETEAARAERAKATLPL
                     GRISGTEEVAAAVLYLASDDAASVVGTDLVVDSGATA"
     aSDomain        16303..16785
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQI70_RS04150_PKS_KR.1"
                     /evalue="1.80E-14"
                     /label="AQI70_RS04150_PKS_KR.1"
                     /locus_tag="AQI70_RS04150"
                     /protein_end="174"
                     /protein_start="13"
                     /score="46.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGAGSGIGRAVALALATEGANVVVTGRRREPLDETVALIEE
                     AGGKALAVAADVSRAADVRSVVAAAVDRFGSLDVAVNNAGVFRGGDPLADLPEEDWHTQ
                     LGINVTGVFLALQAEIRQMRTQPTGGAIVNIASVFGVHGRHPGTAAYAATKAAVSVL"
     CDS_motif       16309..16398
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQI70_RS04150_0001"
                     /evalue="1.40E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="AQI70_RS04150"
                     /protein_end="45"
                     /protein_start="15"
                     /score="17.7"
                     /tool="antismash"
                     /translation="LVTGAGSGIGRAVALALATEGANVVVTGRR"
     gene            complement(17048..17986)
                     /locus_tag="AQI70_RS04155"
                     /old_locus_tag="AQI70_04145"
     CDS             complement(17048..17986)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (15-102). E-value: 1.5e-06.
                     Score: 20.2. Matches aSDomain:
                     nrpspksdomains_AQI70_RS04155_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016435391.1"
                     /locus_tag="AQI70_RS04155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04145"
                     /product="oxidoreductase"
                     /protein_id="WP_062144216.1"
                     /transl_table=11
                     /translation="MSGWTAHDIPDQSGRVAVVTGANSGLGYVTARELARKGARVVLAC
                     RSEVRGAAAVERLVSEVRGADVELTRLDLGDLGCVREFATAFPYGRLDLLVNNAGVMAV
                     PYGTTADGFETQFGVNHLGHFALTGLLLPALLGTPGARVVTVSSPLHALSTIDLHDLNS
                     ERRYRRWLAYARSKTANLLFTHELARRLAAREADVVAAAAHPGYAATNLQTAGPRMAGR
                     RGSEWFMRSATRLLAQSAEAGALPVLYAATAPDVRPDSFTGPSFVHWRGSPAPCRRAPW
                     TVDDRAGELLWEASQRLTGVAYEALGGVSAR"
     CDS_motif       complement(17399..17482)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQI70_RS04155_0002"
                     /evalue="3.20E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="AQI70_RS04155"
                     /protein_end="196"
                     /protein_start="168"
                     /score="0.6"
                     /tool="antismash"
                     /translation="RWLAYARSKTANLLFTHELARRLAAREA"
     aSDomain        complement(17681..17941)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQI70_RS04155_PKS_KR.1"
                     /evalue="1.50E-06"
                     /label="AQI70_RS04155_PKS_KR.1"
                     /locus_tag="AQI70_RS04155"
                     /protein_end="102"
                     /protein_start="15"
                     /score="20.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAVVTGANSGLGYVTARELARKGARVVLACRSEVRGAAAVERLVS
                     EVRGADVELTRLDLGDLGCVREFATAFPYGRLDLLVNNAGVM"
     CDS_motif       complement(17846..17935)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AQI70_RS04155_0001"
                     /evalue="1.90E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="AQI70_RS04155"
                     /protein_end="47"
                     /protein_start="17"
                     /score="23.7"
                     /tool="antismash"
                     /translation="VVTGANSGLGYVTARELARKGARVVLACRS"
     assembly_gap    18067..18843
                     /estimated_length=777
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(18963..20738)
                     /locus_tag="AQI70_RS04160"
                     /old_locus_tag="AQI70_04155"
     CDS             complement(18963..20738)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015116 - sulfate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0008272 - sulfate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354814.1"
                     /locus_tag="AQI70_RS04160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_04155"
                     /product="SulP family inorganic anion transporter"
                     /protein_id="WP_062144219.1"
                     /transl_table=11
                     /translation="MSGAHARGRTRTKERAGKAGALKERAGKAGAPKERGAKPDLANEI
                     TASLVVFLVALPLCIGVAVASGVPAELGIISGVIGGLVVGAVRGSTLQVSGPAAGLAAL
                     VAETVLEHGVAMLGVIVLFSGILQVVLGVVRLGRMFQAISLAVVQGMLAGIGLPLMFSQ
                     AYPMADAKAPGTPIENMAGIPGLFADILTDPQAMIATLLGAATIVLSFVWKKVPGPARK
                     IPAALVAVGIGIAVAALPGVEVKTLQVGNLLASVQVPGAEQFAGLADAAVLTSILTFTV
                     IASAESLFTAAAVDRMHSGPRTRYNTELIAQGAGNTVAGILGALPITAVVARSSANVQA
                     GAKTRISRTLHGLWLLAFALLLPQVLALIPISVLAGVLVHSGWKLFAPTEFPKMWRQDR
                     GEFVVMTVTTLVIVATALLEGVLIGLAAGIVLAALRMSQTVIRQHIEEDTAKVVMAGNA
                     TFLRLPQLIEALESAAASGKPRIRLDLTGVTHLDHACRSQVEEFTAQQRGLGLRVELLM
                     PGPARTEVPAVTAPARPTVPAAAAPGPTDAPAAAAPERPEPGPGAEWFYLDTRPLPGDF
                     GRGHGDYAQGPPLVR"
     misc_feature    complement(21042..21057)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.67"
                     /tool="antismash"
ORIGIN
        1 ccagtaccag tccggcgccc agacccgccg cgtcgacgag ctgaacgccg ccgcgccggg
       61 cccgttcgtg gagctgcacc ccaggctggc ggcgcggctc ggggcggccg agggcgatcc
      121 ggtggccgtg gtctcgcgcc ggggccgggc cgtggccccc gcccgcatca cgaccggcat
      181 ccgcccggac accgtcttca tgccgttcca ctggccgggc gagggccgtg ccaacaccct
      241 gaccaacccg gcgctcgacc cgacgtcgcg gatgcccgag ttcaaggcgt gtgcggtgcg
      301 ggtggaggcg gtcgagtccc aggggtgatc ctgcgacact tgccggcatg ggaagttggg
      361 ggacgctggg cccggcggtg ctgtccctgg cgggcgtcgc gctgggcgcg gccgggtcgc
      421 tgttcgggca gtacctggtg tcgcgggcga gtcaccggca gctggagacc cagcagaacg
      481 ccgaacaccg cgccgaggtg aaggacgtga tcctcaagtt cctggaggtc gcgttccggg
      541 tggagaaggc cgcctcggcc gtcccggacg gcgaggaacc gcccgaggcg ctgctggacg
      601 agctgtggct ggcgcaggcc gagctcgacc tcgcggcccg gacggagccg ctgcgcggcg
      661 cggcccaccg ctacgcggtg cggctgacgt cggctgcccg gggcgaaggc gccgacggcg
      721 acgggctgta ccgggcgaag gtcgcgttca tggatgccgc gtacgacgat ctgtggccgt
      781 ccagtccccg ctcgcgatga ccgggccccg cgtccgcagc cgtgcggcga cgccgaaggc
      841 ggcgatgtac acccaggcgg ggacaggggt gccgtcggac tgccgtacgg cctcccgcac
      901 cacgcgctcg tagaggttgt gcgggtcgcc cggggcgtag tcctccaagc ggtccagggc
      961 gtcgaggagt tcgtcgtagg cctccggcct ggcggtcacc agctcaccgc tcacgactga
     1021 gccgggctcc tcgacggcgt acgggtagcc ggggccgtcg tacagcacga gaccggtcat
     1081 ccgggccggt tcctcgcgtg ccgtacggcc gcgcaggaag cggtcgtggt tgggctcgcc
     1141 ggggcggagg gtgccgtaga cgaagaaggg cagggtcact tcgggccgtc tcctcggcgg
     1201 cggggggctg ggcggtggcg gcgcgagggc cggccgtggc gcagcgtacc ggcgcgggag
     1261 gagggtcagg acaccggcct cagcggcatt cgcggggcag gcaggtcgcc tcggtgctcc
     1321 accggttgcc tgcgggagcg acaccccact cagtactggc gggagcgaca ccccagtccg
     1381 tgccggcggg agccgcaccc cagtcagagc cgaccggaac cgcaccccag tcagaaccgg
     1441 ccggagccgc accccattcg ctgccggcag gcgccgcgct ccattcgctg cccgccgccg
     1501 cgctccccgc ggtcagcacc acgcccgccg cgcccgccac cagcaccacg gtcagccgcc
     1561 cgatcgtctt cctcatcagt ccccctggat gtcgggtgag ttgcctgtcg tcaggtgcgc
     1621 tcagcgtgcc cgccttccgc gcacgccccg accgcattcg acgagaacgc aaacggaacg
     1681 ccccgccggg gcggtcacac caggatcacc ccccttcgca gaaacgatcc tctcccctca
     1741 cacacctcca cgcgctcacc ctgttcatgg catgtgcacg cccccttgaa tcttggtcat
     1801 cttcagtgcc gtcccgttga aggagaccga tgagtcggat acggctgcat gtccgaggtt
     1861 cccgcctggc cacggccggc gctgtcaccg ccaccgccac cttgctggcc gccgcgctct
     1921 ctcccgccgc cgacgcggac gacaggccca ccagggccgg cgcgatcgag aacgcggcag
     1981 aggtcctcgc ggaccgggcg gaaagcctgg ggctgaccac cgcgcaggac accgcggtgc
     2041 gggacgtgat cgtcgacgcg gacggcacgc agcacgtccg ctacgaccgc acataccgcc
     2101 aacttccggt cctcggcggc gacttcgtcg tccacctggc gaaggacggc acataccgcg
     2161 gcgcctctcg cgccacgacc cgaccgatct ccctgtcgag catcgcgccc agcgtctcgg
     2221 cgccgaaggc ggccgacctc gcggcgaacg ccctgcgcgc cgccaacctc ggcgagacgc
     2281 tgaagaagct gacggccagg ccgaagctgg tcgtcgacgc cctgcacggc gccccgaagc
     2341 tggcctggcg gaccgacgtc gtcgcccagg actccctcgg caacccggcc gcccgcacgg
     2401 tgctgaccga cgcccgcacc ggagcgcaga tcgacgcgtg ggacagcatc gagacggcga
     2461 cgggtgacgg gaagtcgctg tacggcggca cggtgccgtt ggagacgacg gtgtcgggat
     2521 cgacgtacca gttgaaggac ccgacgcgcg gcggcaccta cacgggtgac gcggcgaaca
     2581 ggacggacct gtgcgtcctc gccgtctgcc tgaaccgcgc cccggccacc gtcttcacgg
     2641 acgccgacaa ccactggggc accggcacga cggccgagcg ctcgacggcc gcggtggacg
     2701 cgcagtacgg cacggacgtg acgtgggact actacgagga cgtccacggc cgcaggggca
     2761 tcgctggcga cggcaagggc tcgttcaacc gcgtgcacta cgggaagggc tacaacaacg
     2821 ccttctggga cgacagttgc ttctgcatga cgtacggcga cggtgacggc acccagctcg
     2881 ggccgctggt gtcactggac gtggcgggcc acgagatgac ccacggggtc acttcgaaga
     2941 cggccgcgct gacgtactcg ggcgagtccg gcggcctcaa cgaggccacg tccgacatct
     3001 tcggcacact ggtcgagttc cacgcgggca acgcctccga cccgggcgac tatctgatcg
     3061 gcgagaagat cgtccggccg ggcttcggcc gcagcgccct gcgctacatg gacaagccgt
     3121 cgaaggacgg cagctcggtc gactgctgga gcgcgacgac cgcggcgctc gacgtccact
     3181 actcgtcggg cgtcggcaac cacttcgcct acctgctggc cgagggcagc ggcccgaaga
     3241 cggtcaacgg cgtcagctac aactccccca cctgcgacgg ttcctcggtg accgggatcg
     3301 gccgggccaa gctcggcaag atctggtacc gggcgctgac ggtctacatg acgtcctcga
     3361 cgaactacgc gggagcgcgt acggcgacgc tcaacgcggc aaaggacctg tacggggccg
     3421 ggagcgtgga gtacggggcg gtggcggcgg cctggaaggc ggtgaaggtg ggctgagccg
     3481 gtcgcccggt cagagctggt gagcggccgc cccggtggat gggaccgggg cggccgtggc
     3541 agagaagggg ccggggcggc cgtggcagtg gagggggacc ggggccgccg tggcagagga
     3601 gggcgccggg gcggccgtgg cagtggaggg gaccgcggcc gtcccgcgcc tgggcgcggc
     3661 gaaaagcggt ggtgtgcgcg ctgcggcccc ggatacgctc cgctgccgcc tgcccgacct
     3721 ccccgagccg ccacggagcc gtatgccgtc gcccacgaag atgcacgccg aggaactcga
     3781 catcgacgag acgctggtcg cccgcctggt cgcggagcag ttcccgcggt gggccgggct
     3841 gccggtgacg cgggtcgcct ccgccgggac cgacaacgcc atgtaccgcc tgggcgccga
     3901 cctggtcgta cgcctgccgc gcctgccggg cggatcccgc cagatcgaga cggagcaccg
     3961 ctggctgccg cacctggccc cgcatctgcc cctggcggtc ccgacaccgc tggcgctggg
     4021 cgaacccgcc gccggatatg agctgccgtg gggcgtgtac gactggctgg acggcgagaa
     4081 cgcctacgac gcgccgctcg gcgagccacg ggaggccgca ggtgagctgg gccgtttcgt
     4141 ggcggcgttg cgaaaggtgg acgcggcggg cggaccgttg tccttccgcg gcgacccggt
     4201 gggcaagcac gacgcgtacg tccgcaccgc gatccgcgac ctgggcgccg tcggcatgct
     4261 ggacccggcg gtcgcgacag cggcgtggga ggaaaccctg cgcctccccc agtgggacga
     4321 cgcccccgtc tggctccaca gcgacctcct tcccggcaac ctgctgacct cctccggccg
     4381 cctcaccgcg gtcatcgact tcggctgcct cggcgtcggg gacccggcgg ccgacaccat
     4441 cgcggcgtgg gcggtcttcg acgccgcgac ccgcgaggtg ttccgcgatg cggccgacgt
     4501 cgacgacacg acgtgggccc gggggcgcgg gtgggcgctg tgcttcgggc tgatggcgga
     4561 gcaccactac ggcgagagct gcgggaacgg gaccaatccg gtgctggcgg gggtggcgcg
     4621 gcggacggtg ggcgaggtgc tggcggagta ctcgggcggg gcgtgaggac ggcccgggaa
     4681 cggggtacgg cggtatggac gtcccaaatt gcttgcgcct aacctgagtt ggccggatgc
     4741 gggcgggccg gggcgtcggg gggcgggatg gacatcgatg gtcgcgtcga cgcctttgtc
     4801 ggcaacgccc cttccagggc cgtgctgctg cggtccctgc ggggacggga cgtctgtgtg
     4861 cggcgcaatg ccgaccgcgt ctttcccgcg gccagcctga tgaaagtccc gctggccatc
     4921 gcggtgctgg agcagctgga cgccacccga gtggtcaggc gctccgaact cggtcgcacc
     4981 gcctacccct cggtgctgga ggtcttcgac gagcggcacg agttcacact cgtcgaactc
     5041 tgcggcctga tgctcgcgac cagcgacaac cccatcggga cctttctggt ggagctcgtc
     5101 ggcatggagg ccgtgacggc caccgccgag cgggcgggag cacaccacac gcacatgagg
     5161 gtgggcttct ccgaccgcga tctgggcgcg gcggcgcgga gcagcaccac tacggcggac
     5221 gacatggcgc tgatcctgcg gtacgccgcg acgcaagcgc acctgcgtcc cgtcctcggc
     5281 gccctgcgca acagcgtgcg caatttccgc ctgccgctgc ggctgcccga cgatctgaaa
     5341 gtcgcccaca agaccggcag cctgcgccgc ctggcacacg acgcgggcat tctcttcggc
     5401 cgccaccacg acctgatcgc cgtgttcctc acggaggacc aggcggacac cgcagcggtc
     5461 ggcatccaga tcggcgactg catggcagat gtctggcggc tgctcggtga acccgtgtag
     5521 ccggctctcc cccgggagtc ctgatgagcg atcagcggcg tgtcatcgcg gaagtccgac
     5581 gcacagtgcg catctacaac ctgctggtcc tggtggtcgg ggcgatcgct ctggtcgtct
     5641 ccgtcgaccg cgcccaggac gacgtcctcg tcacctcact cgaagtcgtg gggacgacac
     5701 tggtctcggc cgcgctggtc agcttcattt tcgggcagat caccatccgg gacacgacat
     5761 tgcaggtgaa cgaggccatc gaccaggcgc tgcgcgaggt ccttgagccc atccgggaga
     5821 acctcttcgc cggggccctg tcccactacc gctgggactg ccacctggac ggtctcgaac
     5881 ccgacggata cgccgttcag gccatgcgtg tctcctacca ggtgcaggtg atcccccggg
     5941 aactgcgctt catctgtgtg tcgtcactga cggacgagtc cttcagccgg ctggccggcg
     6001 acctcaggta tgtgctgcgc tggcaggtgg acgaggggct ggagttgacg gacccccact
     6061 gcttccatgt cagtcatgtc cgggtcgacg ggcagcaact ggaccagccg gcaccgcgtc
     6121 cgaccacctt gcgcggctct ccggcggtcg agtaccgctt ccaggtgtcc gaactgcgcc
     6181 ggcatcacgg attccactcc gtcgagttcc atgtggtcgc ccgcaaatac ctcgggacgg
     6241 atcgtgaggt cagggttcag gcctacgctt tccggtccct gctggacgcc gagtaccgtc
     6301 tgaccgtcgg ggagtcgatc ggtgccgaga tcctgaacac tcagatctcg gggctgagcc
     6361 gaatcggtgc cggtggactg atccagcacg gccggaccta tccggacgcg ttcggccggg
     6421 tcgccgccta cgcgatcttc accactccgc tgcagaccgg cagcaatgtc gtgttcacca
     6481 tcgaccgcgg caacccgcgc agggcgaacc gaggcggtgc ggcatcgtga aagccgcatt
     6541 gaccgcaagt gtcgctcaac catgtcgccg gtgatcccgg cagatggacc cgggccacgc
     6601 tgaccgaacg gctggcggtc tacgaagacc tcgggatcgg tttcgacggc gtcttcgacg
     6661 atctcgccgc ccgtgggtgg ctgacggagg acgggggtgc gatgacgttg accgaggccg
     6721 gggaggccgg gcgccttcgg gccagggagc ggaacctgcg cgtccatcgg cagctgcatg
     6781 aaggcgtcga cacggccgac ttcgtgacca cggtcaatgt gctgcggcgg atggtcgcga
     6841 atctgggtgg caacggcgat ctgcctgagt gagggggacg cgggcgacgg gtcggccggg
     6901 gaacggctgt gggcgggtcg gctgcgggcg ggtcggctgt gggcaggtcg actgcgggcg
     6961 ggtcggctgc gggcgggtcg gctgcgggcg ggtcggctgt gggcgggtca tccggggcgg
     7021 gtcacccgtt cacacgcgcg gtcccccact caacaggttc tcttccgcga cacccccggg
     7081 acgcggccat gacctgctga aacagcgccg agtcccggac cccgtcccgt ccgcccgaca
     7141 cccgttcatc ccatttctga cgctctctca ggaagcgcgc ccgccccgct gccccttacc
     7201 tcggaagggc agggcacgac cgaggcggcg gcacatgggg gtgtcgcggg ccgtggcccc
     7261 gctgagtgcg gaggaacgct gatgcgacgt accgcccgtc tgctgacagg gaccgcgctg
     7321 gccgtgggcg ccgtggggct cggcggcatg cccgcgtacg gcgacgacgt cggtggcctc
     7381 aaggtgctcc cgtcctcggt cgtgccgggc gggcaggtga cggtgaacac ggcgtcctgc
     7441 ggggacggcg gttcggccga gggcgacgcc agcgcggtgg gcgccgggtc cttcacgctg
     7501 gcgccgagga cgcacgagca cgacgcgacc ggaaagttcc aggtgccgcc gagcgcgcag
     7561 ccggggacgt acgagatcgt cgcgacctgc gccgagggcg gccggcgggt gacgggcgac
     7621 ctggtggtca cgctgacggc cccgcgcgaa caggtgcatc cgcgaggaag tgtgaagacg
     7681 ggggtcggcg gcgctcttgg ccccgatccc gtgcagaccg cggccggcgt ggcggctctc
     7741 gccgtcgccg ccgcgggcgg tacctggctc ctgcatcgcc gggcgagagg cgacgggatc
     7801 tgatggacac cctccgctgt ccgtccgccg gtaccgcacg tcccctcccc ctccgggtcc
     7861 gacgcccctc gcggcccgga gggggatcag ggcggcacga gaggagtccg aggaggctcg
     7921 cgtgcgcagt caccgcagcg tcggcaacgc cgccatagcc accgcgaccg ccctcgccct
     7981 ctgctccggc gcctggctgc tgcgcaacgg cgccgagacg cacacgccgc cgcagccgtc
     8041 ggccgcacaa gcggcggcgc agagcgggga caccggtcgt ggtgacccgc acccgcgcgc
     8101 ccggcgctcg gccgcccccg cgctcccgcc ctctcctccc gaccgcatcc gcattccctc
     8161 gatccgcgtc gacgctcccc tcatgggcct gggcctgacg aggacgggca gcctcgacgt
     8221 cccgcccgcc gagcgcagga acctcgccgg ctggtacgag gccggcacca cacccggtga
     8281 gaccggcacc gcgatcgtcg ccgggcacgt cgacaacgcc gacggacccg ccgtcttcta
     8341 ccacctgggc gccctgaaga agggcagcac gatcgaggtg gaccgacggg acggcggcac
     8401 cgccctcttc tcggtcgacg ccgtcgaggt ctacgacgcg aaggacttcc ccgacaagaa
     8461 ggtgtacggc gcggccccgc gccccgagct gcgggtgatc acctgcggcg gcggttactc
     8521 acggacgacc gggtatcagg gcaacgtcgt ggtcttcgcg cacctcaccg gcagccggtg
     8581 acggcgccag gacgttccgc ttcccccact cgcccagcgg ctccagtgcc gtgttgaggg
     8641 tctcgcccct cggcgtcagc gagtactcca cgcgcggcgg cacctcgtcg aactcctccc
     8701 ggtgcacgat cccgtccgct tccagttccc gcagctgggc ggcgagcacc ttctccgtca
     8761 ccccgggcag ctcgcggcgc agctccccga agcggtgcgg acgcacatgc agcgcccaga
     8821 ggatgagcac cttccacttg ccgccgatca catccatcgc cgcgtcgaca ccacactcgt
     8881 acgaccccgg ccgccgtccg atcgccatgc ccgccactcc cccgtcctgt cccctgcacg
     8941 cttccctcaa ggtaaccacc cactcgaaag tacgtacttg agcaggcagt tcacctctac
     9001 gaggctaacc gccatgactg acaacgcgac tgacaaagcc tcttccccga cccctgtcac
     9061 cctcctcggc accggcgcca tgggcaccgc gctcgcccgt gcctggctcg ccgccgggca
     9121 ccccgtgacc gtctggaacc gcacccctgc ccgcgccgag gcgctggccg tcgagggcgc
     9181 cacggtcgcc gcgagcgcgg acgccgccgt ggccgccaac cggctcgtcg tcgcctgtct
     9241 gctcgacgac gactccctcg gcgaggccct cgccacggcc gacctcggcg gacgcgacct
     9301 cgtgaacctc accaccggca cgcccggcga gggccgcgcc cgtgccgcct gggccgaggc
     9361 gcgcggcgcc cgcttcgtcg acggcgggat catggccgta ccgccgatga tcggcagccc
     9421 ggacagcggg gcgttcgtct tctacagcgg atccgccgcc ctcttcgagg agcaccggga
     9481 cgtcctcgcg gtaccggcgg gcaccgccta tgtcggcgcg gacgccggct tcgcggccct
     9541 gcacgacgtg gcgctgctga gcgcgatgta cgggatgttc ggcgggatcg cgcacgcctt
     9601 cgcgctgatc cgccgggagg acatcgctcc cgaggacttc gccccgctgc tcgtgtcgtg
     9661 gctgaccgcc atggcgcccg ccgcgctgga gagcgccggg aagctggaga gcggcgacta
     9721 cacgcgggat gtcgtctcca acctcgccat gcaggtcgcg gggatcccga cgttcctgcg
     9781 gacggcagac gagcagggtg tacgaccgga catggtgcgg ccctacctgg acctgatgcg
     9841 ccgccgcctg gagtccggcc cgcacgccga cgaggacacc accggggtga ttgacctcct
     9901 gacagcgacc tgaggtgcgg gaatcggcca tacaggcgtg gatcctgcgt gacggaaaag
     9961 cgatcttgcc gtgttctcgg cggagccgga ccatgcgggc gtggactccg acccggactc
    10021 gtcgctcagc gtggacgccg cgcaggtgaa ctccgtcgtg cgccatgacg cggcgctgct
    10081 ggaggacgac ctgcgcgcgt tcctcaagtc actgacggcc gccccggacg acggttcggc
    10141 cgacggttca gcggccgtgt gcgccaccgc cctgcaccgc tcgctgcacc gctccctgta
    10201 cacacccgtg tccgacgcgc tcggctccaa ggtgggccag caggccctgc ctccgtccgc
    10261 gggcgcgccc ggcggtacgg ctccgttgcg gccctcgatg gtgtactggg cgtaccgcaa
    10321 ctaccggggc tttcccgaag ggccggggag cgaggaggca tccgccgacc tggccgtcgt
    10381 gcggcgggcg gcggtggcgg tgcgggtcct gctgaaggcc gcggtggtgc tggacgacat
    10441 ccaggacggc agcgccatgc gctacggcga gcccgcgctg cacatcaccc acggggtgcc
    10501 cgtcgcgctc aacaccggct cctggctgat cacggcggcg ctgcggcacg cggcggaccc
    10561 cggcgtggtg gacagcctga tccgcggtgt cggccacggc ttcaccggcc aggcgctcga
    10621 cctggcgacg aggtccgcgg acacccgtgc cgacctgctg gccgcaccgc acgaggaacg
    10681 ggtgcgcttc tgggagtcgg tcgccgcgcg caagaccggc acgctgttcc ggatgccgct
    10741 cgacgcggcc ctcgccgcgc tgggcgtcgt cgaggaggag cggcacgccc tggacggggc
    10801 catgcgccgg ctcgggctgg cgagccagct gttcaacgac ctgaccgacg tcgtaccgga
    10861 actcggcggc gccaagaccc accaggactt cgacgggctg ggcaaccggg tgttcctgga
    10921 gctgctcgac tcgccgccgc gcccgccgcg cccgtcggac ccggacgggc tgacgggcgc
    10981 gcggctgaag tcgtatgtcc tcggccaccc gaggctgcgc gacaccctcc tcgatctctc
    11041 cgcccaggcg gtcgagtgga aacggtcggc gaaggaggcc gtgcgggggg tgtgccggtc
    11101 ggcgcgcagc gcggcctact tcgacgtgac catcgagcgc aagggccacc tcatcgaccg
    11161 cctgcacgag acgctccggc agcgcagcgg cgccaccggg tgaccgtgtc gtagacgatg
    11221 ccggccgcac ccggacgggg gccgggcgcg cgcacccgac ccccgtcgca ccccacctca
    11281 cagcccgccc gcaccgcgcc ctccgaaccc tcacacccgc ccccggccct cgctgagggc
    11341 agcgttcctc gcgggaaaca gacgtgatgc ggtcgggaaa caccggcatc gcacgctcct
    11401 gggcatgacc tcgaatacgc gtgtggtggt gatcggcgcc ggcctcgcgg gcgtacgact
    11461 cgcccggcgg ctcggcgagc tcggcacgcc cgtgacgctc gtcggcgatg aggagcaccg
    11521 cccgtacaac cgggtcctgc tcgccgaggt gctggccgga cggtacagcc ccgaggtgat
    11581 cgccctcccg gcgcccgctg agctcacccg tggccgggtc accggcatcg accgcgaggc
    11641 gcgagccgta cacctcgcgg acggcacgga gatcgcatac gacacgctcg tgctggccac
    11701 cggctccaac ccggtgctcc cgccgctgcg cggcctgttc acgcctgacc atgtgctgcc
    11761 ggagggcgtc cacgccttcc gcaccatgga cgactgcctg ggcctgtcca aggcggtacg
    11821 gccgggcgtg cgggcggtcg tgatcggcgg cgggctcctc ggggtctccg cggcccgcgc
    11881 gctggcgatg cgcggcgcgc aggtcgtgct ggcccagcag tccgagcggc tgatggagcg
    11941 gcagctcgac ccggccgcct cgaagctggt caggcgccac ctcaccgagc tgggcgtcga
    12001 ggtgcacacc gagtgccgcg tccgtgacgt gcgctgcgta ggcggcgcgg tccgctcggt
    12061 ggagatggcc gacggttacg ccctcgacgc cgacctcgtg gtcctggcct gcggcgtgcg
    12121 tccgcgtgcg ggcctggcgc aggccgccgg gctggacgtc cgcaagggga tcgtcgtcga
    12181 cgacgagctc cgtacgtccg acccgcacat ccgggccatc ggcgactgca cgcagcacga
    12241 cggcacggtg tacggcctcg ccgcccccgc gctcgaacag gccgacgtcc tggccgagtc
    12301 gctgagcggg aacgcgggcg cccgctacac cggaacccgt tcgcttaccc ggctcaccct
    12361 cgccgggcag accgccttcg acctcgccgc gttcggcgag acggaggccc ggcccggcga
    12421 cgacgtcgta cagctcgccg acgccacccg cggcacctac cgcaaggtcg tcgtccgcga
    12481 cgaccgcctg gtcggcgggg ttctcgtcgg cgaactcggc accgtcggcg cgctcgcccg
    12541 cgcctgggag ggagcagagc cgctccccga cgacggtcct ctgctccacc tgctcaccaa
    12601 cgatggaggc tcctgatgac cgccactggg gcgaacccca cgatcgtgct cgtcggccat
    12661 ggcatggtcg gccagcgctt cctcgaagcg ctcgccgagc gcggcctgac cgccacgcac
    12721 cgcgtggtcg tgctgtgcga ggagcctcgt ccggcgtacg accgcgtggc gctgacctcg
    12781 tacttctcgg gcaagacgcc cgaggacctc tccatgaccg acatggagtt catcaaggac
    12841 cacggcatcg agctgcacat cggtgacccg gcggagacga tcgaccggga ggcgcggaag
    12901 gtcaccgccc gctccggtct cgtcgtggac tacgacgtcc tggtcctggc caccgggtcg
    12961 tacccgttcg tgccgcccgt cccgaacaag gacgccaccg gctgtttcgt ctaccgcacg
    13021 atcgaggacc tgctcgcgat cgaggagtac gccaggacga aggccacctc cggcgccgtg
    13081 gtcggcggcg gtctgctggg gctggaagcc gccggtgcgc tgaagggcct cggcgtcgag
    13141 acgcacatcg tggagttcgc gccgcgcctg atgccggtgc aggtcgacga gggcggcggc
    13201 gccgcgctgc tgcgcaccat cgaggacatg ggtctgacgg tccacaccgg ggtgggcacg
    13261 caggagatcg tgacggacgc cgagggtgcc gtcaccggta tgaagctgtc cgacggctcc
    13321 gagctcgcca ccgacatggt ggtcttctcc gccggtgtcc gcccccgcga ccagctggcc
    13381 cgcgactgcg gtctcacggt cggcgagcgc ggcggcatca ccgtcgacga gcagtgccgt
    13441 acggtctccg acccgcacgt gttcgcgatc ggcgagtgcg cgctggccgc cgacggccgg
    13501 gtgtacggcc tggtggcccc gggttacgag caggccgaga cggccgccgc gacgatcgcc
    13561 gaggacgagg cggagttcac cggcgccgac ctgtccacca agctgaagct gctcggcgtg
    13621 gacgtggcgt ccttcggtga cgcgcacggc accgccgagg actgcctgga cgtcgtctac
    13681 tccgactccc gcgcgggcct gtacaagaag ctggtcatcg gccgcgacgg cacgctgctc
    13741 ggcggcatcc tggtcggcga cgcggacgcg tacggcacgc tgaaggcctt caccggctcc
    13801 gtcccgccgg tctcgcccga gtcgctggtg ctgcccgccg gtgccggggc ccccgcccag
    13861 ctcggcccgt ccgcgctgcc ggacgacgcg gtcgtctgct cctgccacaa cgtcaccaag
    13921 ggcaccatcc gcggcgcggt caccgaccac cagtgcacga ccgtgcccga ggtgaagaag
    13981 tgcaccaagg ccggcaccgg ctgcggctcc tgtgtcaagg tgctcggcca gctggtcacc
    14041 gccgagctgg aggcgtccgg cgtcgaggtc gacaagggcc tgtgcggctg cttctcgcag
    14101 acccgcgagg agctgtacga gatcgtcctc gccctgcgca tcaacaccta ccaggacctg
    14161 ctggaccgct acggccgcga gaacgcccgc ggcaccgacg gctgcgagat ctgcaagccg
    14221 gcggtgggct cgatcatcgc ctccctcgcc ccgacgatcg gagcgagcgg ctacgtcctg
    14281 gacggcgagc aggcggccct gcaggactcc aacgaccact tcctcgccaa catccagaag
    14341 aacggctcgt actcgatcgt gccgcgcatc cccggcggcg agatcacccc ggagaagctg
    14401 atcgtgatcg gcgaggtcgc ccgcgacttc ggcctctaca cgaagatcac cggcggccag
    14461 cgcatcgacc tgttcggcgc gcgcgtcgag cagctcccgc tgatctgggc gcggctggtg
    14521 gacgcgggct tcgagtccgg ccacgcctac ggcaaggcgc tgcgcacggt gaagtcctgc
    14581 gtcggacaga cctggtgccg ctacggcgtc caggactccg tccggatggc gatcgacctg
    14641 gagctgcgct accgggggct caggtcgccc cacaagctga agtcggccgt ctccggctgc
    14701 cagcgcgagt gcgcggaggc ccagtcgaag gacttcggcg tcatcgccac cgccaacggc
    14761 tggaacctct acgtcggcgg caacggcggc gcgaccccgc gccacgccga cctgctggcg
    14821 caggacctgt cggacgccga gctgatccgc ctgatcgacc gcttcctgat gttctacatc
    14881 cgcaccgcgg accgcctgga gcgcacctcg acctggctgg agcggatccc cggcggcctg
    14941 gaccatgtgc gcgaggtggt cgtcgaggac tccctcggca tctgcgagga gctggagtcc
    15001 ctgatggcgg cccacgtcgc gaactaccgc gacgagtggg cggagaccat caacgacccc
    15061 gagaagctgg cccgcttcgt ctccttcgtc aacgcccccg acacccccga cccggtcgtc
    15121 ggcttcgtcc ccgagcgcga ccagatcaag cccgccctgc cgctgctgac catcggccac
    15181 cgtcccctgg aaggaagcgc ccagcgatga ccctggcacc cgagacaacc gacctgaagg
    15241 tccaagtacg gctggacgac gactggttga ctgtctgcga cctgacccgg ctgctcccgg
    15301 gccgcggtgt ggcggccctg ctgccggacg gccgccaggt ggccctgttc cgcgaccgcg
    15361 ccggacagct gtacgccatc gacaaccgcg acccgttcgg cggcgcggcc gtcctctccc
    15421 gcggcctgac cggcacccac cagggccgcc cgttcgtggc ctcgcccctg ctgaagcagc
    15481 gcttcgacct ggagaccggg cagtgcctgg acgacgaggc ggtgcgggtg gcgacgtacg
    15541 agatccgtac ggcctgacca tctacggcac ttgaccgatc gttccagaaa aacctaggct
    15601 gttcgtcgtg gccaggacca aggagttcga tccggacgcc gcgctgcagt cagctcttga
    15661 gctgttctgg cagcgcggct acgaggcgac gtcgatgtcc gacctcgtcg agcacctcgg
    15721 cgtcggacgc gccagcctct acgcgacctt cggcaacaag cacgagctgt acctgaaggc
    15781 gctggaccgc tacgagcggg cgggattcac gccgatcgtg cgggagctgt cccagccggg
    15841 gcccgccctg ccgtccgtgc ggtcggtcgt caggcggtac gcgaccgagg ccgccgacga
    15901 acgactgcgc ctgaacggct gcctggtcac caacacggcg gcggagctcg ccccgcacga
    15961 ccgggcagcc gcccggcagg tggagcgcaa ctgggaccag ctggagaccg tgctgcactc
    16021 ggcactggtc cgcgcccagg cccaggggga actgcccgcc ggccgcgatc cgctcgccct
    16081 cgcccgcatg ctgctggtcc tgctccaggg cctcagggtc gtgggcaagg cgtcctcgga
    16141 cccggcccgg gtccgggacg cggcagagca ggcgctgaca ctgctcgact gagacgccct
    16201 tcgtccgagg ggcgtttttc aggcccgaat aatgaaccga tcggtcaaga aaaaggggag
    16261 atcatgacca ccgcagccca ccgcacccgc ttcaccgaca ggaccgccct cgtcaccggc
    16321 gccggttccg gcatcggacg ggccgtcgcg ctcgcgctcg ccaccgaggg cgcgaacgtc
    16381 gtggtcaccg gccgcaggcg cgagccgctc gacgagacgg tggcgctgat cgaggaggcg
    16441 ggcggcaagg cgctcgcggt cgccgcggac gtctcccgtg cggccgacgt gcggtccgtg
    16501 gtggcggccg ccgtggaccg cttcggctcc ctcgacgtgg cggtcaacaa cgcgggcgtc
    16561 ttccgcggcg gcgacccctt ggccgacctc ccggaggagg actggcacac ccagctcggc
    16621 atcaacgtca ccggcgtctt cctcgccctc caggccgaga tccgccagat gcgcacccag
    16681 ccgacgggcg gcgcgatcgt gaacatcgcc tccgtcttcg gggtccacgg ccgccatccc
    16741 ggcaccgccg cgtacgccgc gaccaaggcc gccgtctccg tcctcaccag gggcgccgcc
    16801 ctcgaccaca tcggcgacgg cgtccgcatc aacgcggtca gccccggcgc cgtcgacacc
    16861 cccatgtccc tgctccccgg cgagacggag gcggcccggg ccgagcgggc gaaggccacc
    16921 ctccccctcg gccgcatctc gggcaccgag gaggtggccg cagccgtcct ctacctggcc
    16981 tcggacgacg ccgcgtcggt ggtgggcacc gacctggtgg tggacagcgg ggccacggcc
    17041 tgagcgctca ccgggcgctc acacctccca aggcctcgta cgccaccccc gtcagccgct
    17101 gcgaggcctc ccagaggagt tcgcccgccc ggtcgtcgac ggtccagggc gcccgcctgc
    17161 acggggcggg cgagccacgc cagtggacga aggacgggcc ggtgaaggag tcgggccgga
    17221 cgtcgggtgc ggtggcggcg tacaggacgg gcagcgcgcc ggcctcggcg gactgggcga
    17281 gcaggcgagt ggcgctgcgc atgaaccact cactgccccg gcgacccgcc atgcgcggtc
    17341 cggcggtctg caggttggtg gccgcgtacc cgggatgcgc ggcggcggcc accacgtccg
    17401 cctcccgcgc cgccagcctg cgcgccagct cgtgcgtgaa gagcagattg gcggtcttgg
    17461 accgggcgta ggcgagccaa cgcctatagc gtcgctcgct gttgaggtcg tggaggtcga
    17521 tggtggacag cgcgtgcagc gggctggaga cggtcaccac ccgcgcgccc ggcgtgccga
    17581 gcagcgcggg cagcagcaga ccggtgagcg cgaagtgccc gaggtggttg accccgaact
    17641 gcgtctcgaa gccgtccgcc gtcgtgccgt acggcaccgc catcaccccg gcgttgttca
    17701 cgagcaggtc cagccggccg tacgggaagg ccgtggcgaa ctcccgtaca cagccgaggt
    17761 ccccgagatc cagccgcgtc aactccacgt cggcgccccg cacttccgac accagccgct
    17821 ccacggccgc cgcgccccgc acctcgctgc ggcaggcgag caccacccgg gcgcccttgc
    17881 gggccagctc ccgcgccgtg acgtaaccga gcccgctgtt ggccccggtg acgacggcga
    17941 cgcgtccgct ctggtcgggg atgtcgtgcg cggtccagcc ggacatggca gggctccttc
    18001 cgcgggcggg tccgggccca ggtacctcat cagcctgcgc cgaaacgacc cccgagaaca
    18061 gatcggnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18181 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18241 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18301 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18361 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18421 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18481 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18541 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18601 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18661 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18721 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18781 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
    18841 nnncggtatc cggctttccc ggatcggcgg gcgggcctgc gacccgccag ccgggccgac
    18901 gggctcgcag accgcggcga tcgcaccaac gggcggggct cagcacaccg gcggccgagc
    18961 gctcagcgca ccagcggcgg gccctgcgcg tagtcgccgt ggcctcggcc gaagtccccg
    19021 ggcaggggcc gagtgtccag atagaaccac tcggcgccag ggccgggctc cggccgctcg
    19081 ggcgcggcag cggcaggcgc gtccgtcggc ccgggcgcgg cagcggcagg cacagtcggt
    19141 cgggcgggcg cggtgacggc agggacctcc gtcctcgccg gtcccggcat cagcaactcc
    19201 acccgcagcc ccagcccccg ctgctgcgcc gtgaactcct ccacctggct gcggcaggcg
    19261 tggtccaggt gcgtcacgcc ggtcaggtcc aggcggatgc gcggcttgcc cgacgccgcc
    19321 gcgctctcca gcgcctcgat gagctgcggc agtcgcagga acgtcgcgtt gccggccatg
    19381 acgaccttgg cggtgtcctc ctcgatgtgc tgccggatca ccgtctggga catgcgcagg
    19441 gcggccagca cgatcccggc cgcgaggccg atcaggacgc cttccagcag tgccgtcgcc
    19501 acgatgacca gggtcgtcac cgtcatcacc acgaactcgc cccggtcctg ccgccacatc
    19561 ttcgggaact ccgtgggcgc gaacagcttc cagccgctgt gcacgaggac gcccgccagc
    19621 accgagatcg ggatcagggc cagcacctgt ggcagcagca gggcgaaggc cagcagccac
    19681 aggccgtgca gggtgcggga gatacgggtc ttcgcaccgg cctggacgtt cgccgagctg
    19741 cgggccacga ccgccgtgat cgggagggcg ccgaggatgc ccgcgaccgt gttgccggcg
    19801 ccctgcgcga tgagttcggt gttgtagcgg gtgcgggggc cgctgtgcat acggtccacg
    19861 gcggccgcgg tgaacaggct ctccgcggag gcgatgaccg tgaaggtgag gatggaggtg
    19921 aggaccgcgg catcggcgag ccccgcgaac tgctcggccc ccggcacctg caccgacgcc
    19981 agcagattgc cgacctggag ggtcttcacc tccacgccgg gcagcgcggc gaccgcgatg
    20041 ccgatgccga ccgcgaccag cgcggccggg atcttccgcg ccgggcccgg caccttcttc
    20101 cacacgaagc tgagcacgat cgtggcggcg ccgagcaggg tggcgatcat cgcctgcggg
    20161 tcggtgagga tgtcggcgaa caggcccggt attccggcca tgttctcgat cggcgtgccg
    20221 ggggccttgg cgtcggccat cgggtaggcc tggctgaaca tcagcggcag cccgatgccg
    20281 gccagcatcc cctggacgac cgcgagggag atcgcctgga acatccggcc gaggcgtacg
    20341 acgcccagga cgacctgcag gatgcccgag aacaggacga tcacgccgag catcgccacg
    20401 ccgtgctcca gcaccgtctc cgcgaccagc gcggcgagtc cggcggcggg cccgctgacc
    20461 tggagcgtgc tgccccggac tgcgcccacc accaggccgc cgatcacacc ggagatgatg
    20521 ccgagctcgg cggggacgcc ggaggcgacg gcgacgccga tgcacagggg cagggcgacc
    20581 aggaagacga ccagggacgc ggtgatttca ttggcgaggt cgggcttcgc gcccctctcc
    20641 ttcggcgccc ccgccttccc cgccctctcc ttcagtgctc ccgccttccc cgccctctcc
    20701 ttggtgcgcg tacgcccgcg cgcatgcgcc ccgctcatcc ggcatgcacc cggaaccggc
    20761 cgtcgtcctc cagctcgtac acctgcccgg tgtcgacctc gtagtaccag ccgtgcagcc
    20821 gcagccgccc cgcgtccagc cgctgccgca cgacggggta ggtccgcagc accgcgatct
    20881 ggttgacgac attgcgctgt acgacgtcgg acagggacag ctcgccggag cccggggtga
    20941 gaaccggcgc cagttcgggg cgggccagtt gcagccaggc gtccacgccg ggcagcgcgg
    21001 acaggtcgtc gccggacttc agcgcaccca tcgctccgca gtgtgagtga ccgcacacga
    21061 cgatgtcctg aaccccgagc acctccagtg cgtactcgat ggtggcggcc tccccggacg
    21121 ctccggggct gccgtacggc ggcacgatat tgcccgcgtt gcgcagctcg aatatttctc
    21181 cgggccgcgc gccggtaatc agg
//
