LOCUS       NZ_KQ947984            10405 bp    DNA     linear   CON 21-APR-2024
DEFINITION  Streptomyces curacoi strain DSM 40107 PRJNA299217_s001, whole genome
            shotgun sequence.
ACCESSION   NZ_KQ947984
VERSION     NZ_KQ947984.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces curacoi
  ORGANISM  Streptomyces curacoi
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1266825)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Draft genome sequence of Streptomyces curacoi DSM 40107, type strain
            for the species Streptomyces curacoi
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 1266825)
  AUTHORS   Ruckert,C., Winkler,A., Kalinowski,J., Kampfer,P. and Glaeser,S.
  TITLE     Direct Submission
  JOURNAL   Submitted (30-OCT-2015) CeBiTec, Bielefeld University, Sequenz 1,
            Bielefeld 33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 13-OCT-2014
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 65.7x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001513975.1-RS_2024_04_21
            Annotation Date                   :: 04/21/2024 02:05:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,531
            CDSs (total)                      :: 7,455
            Genes (coding)                    :: 7,251
            CDSs (with protein)               :: 7,251
            Genes (RNA)                       :: 76
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 70
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 204
            CDSs (without protein)            :: 204
            Pseudo Genes (ambiguous residues) :: 0 of 204
            Pseudo Genes (frameshifted)       :: 91 of 204
            Pseudo Genes (incomplete)         :: 154 of 204
            Pseudo Genes (internal stop)      :: 21 of 204
            Pseudo Genes (multiple problems)  :: 54 of 204
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:06:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 94196
            Orig. end                         :: 104601
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            KQ947984.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10405
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="ectoine"
                     /region_number="1"
                     /rules="ectoine_synt"
                     /tool="antismash"
     cand_cluster    1..10405
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="ectoine_synt"
                     /kind="single"
                     /product="ectoine"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10405
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5405](+)"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5405
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="ectoine_synt"
                     /neighbourhood="5000"
                     /product="ectoine"
                     /protocluster_number="1"
     misc_feature    complement(100..111)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            1404..1907
                     /locus_tag="AQI70_RS00435"
                     /old_locus_tag="AQI70_00435"
     CDS             1404..1907
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0019239 - deaminase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240: riboflavin biosynthesis protein RibD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007444204.1"
                     /locus_tag="AQI70_RS00435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_00435"
                     /product="nucleoside deaminase"
                     /protein_id="WP_062142429.1"
                     /transl_table=11
                     /translation="MTTHTQETSVQEFERAWMEKAIRLATHSVTDGGGPFGALVAKDGA
                     VVAIGHNQVTATLDPAAHAEVSAMRAACRELDTFSLDGCVLITSCEPCPMCLSAALWAR
                     VDRVVYCADRHDAAVAGFDDRRFYDLFEKRPQSMWPMAVERLDLPNRTAPFDAWLAKSD
                     RVDY"
     gene            <1987..>2100
                     /locus_tag="AQI70_RS39925"
                     /pseudo=""
     CDS             1987..>2100
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468719.1"
                     /locus_tag="AQI70_RS39925"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="bifunctional RNase H/acid phosphatase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTALVLLRHGETPLTPQKRFSGSGGSDPPLPEAAWRQA"
     gene            2310..2837
                     /locus_tag="AQI70_RS00440"
                     /old_locus_tag="AQI70_00440"
     CDS             2310..2837
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004002247.1"
                     /locus_tag="AQI70_RS00440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_00440"
                     /product="DinB family protein"
                     /protein_id="WP_062142431.1"
                     /transl_table=11
                     /translation="MTSDAPLTLPDGRPVPLLTGDERPMLESWLDFHRATLELKCAGLD
                     DAQLRLASAEPSELTLLGLVQHLAECERNWFQRVVGGLDVPPVYGEKSGYSLDPGRGVD
                     EALAVWRREIARGREVCAGRSLDGVGRIADGPMAGVEVSLRWVLIHMIEEYARHNGHAD
                     ILRERIDGVTGA"
     misc_feature    2454..2456
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    2961..2978
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.75"
                     /tool="antismash"
     misc_feature    complement(2963..2978)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.62"
                     /tool="antismash"
     misc_feature    2973..2988
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    3081..3096
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 17.69"
                     /tool="antismash"
     misc_feature    3107..3119
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     gene            3144..3650
                     /gene="ectA"
                     /locus_tag="AQI70_RS00445"
                     /old_locus_tag="AQI70_00445"
     CDS             3144..3650
                     /EC_number="2.3.1.178"
                     /GO_function="GO:0033816 - diaminobutyrate
                     acetyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019491 - ectoine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ectA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004002246.1"
                     /locus_tag="AQI70_RS00445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_00445"
                     /product="diaminobutyrate acetyltransferase"
                     /protein_id="WP_062142433.1"
                     /transl_table=11
                     /translation="MTAAQADLQIDRPAVADGAALWRIARDSKALDLNSSYSYLLWCRD
                     FAGTSAVARDERGEPVGFVTGYVRPERPHTLLVWQVAVDGAYRGRGIAARLLDGLVARV
                     GGEYGITSVETTITPGNTASERLFGSFAERHGARVEREVLFDTGLFPDGPHDPEVLYRI
                     GPLSL"
     gene            3682..4953
                     /gene="ectB"
                     /locus_tag="AQI70_RS00450"
                     /old_locus_tag="AQI70_00450"
     CDS             3682..4953
                     /EC_number="2.6.1.76"
                     /GO_function="GO:0045303 - diaminobutyrate-2-oxoglutarate
                     transaminase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (28-366). E-value: 6.8e-73.
                     Score: 237.5. Matches aSDomain:
                     nrpspksdomains_AQI70_RS00450_Aminotran_3.1"
                     /codon_start=1
                     /gene="ectB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007448159.1"
                     /locus_tag="AQI70_RS00450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_00450"
                     /product="diaminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="WP_062142435.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.6e-76, bitscore:
                     253.7, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTITQPDLSVFETLESEVRSYCRGWPTVFDRARGSRMYDEDGHEY
                     LDFFAGAGSLNYGHNNPVLKRALIDYLERDGVTHGLDMSTSAKRAFLQTFQDLVLRPRD
                     LPYKVMFPGPTGTNAVESALKLARKVKGREAIVSFTNAFHGMSLGSLAVTGNAFKRAGA
                     GIPLVHGTPMPFDNYFDGTVPDFLWFERLLEDQGSGLNKPAAVIVETVQGEGGINVARP
                     EWLRALAELCERQDMLLIVDDIQMGCGRTGAFFSFEEAGITPDIVTVSKSISGYGLPMS
                     LCLFKPELDVWEPGEHNGTFRGNNPAFVTATAALESYWADGSAMEKQTRTRGEQVEQGL
                     IAICEENLADVKEYRGRGLVWGMEFHDKERAGRVARRAFELGLLVETSGPESEVAKLLP
                     ALTITPDELDEGLSILARAVRETA"
     aSDomain        3766..4779
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQI70_RS00450_Aminotran_3.1"
                     /evalue="6.80E-73"
                     /label="AQI70_RS00450_Aminotran_3.1"
                     /locus_tag="AQI70_RS00450"
                     /protein_end="366"
                     /protein_start="28"
                     /score="237.5"
                     /tool="antismash"
                     /translation="FDRARGSRMYDEDGHEYLDFFAGAGSLNYGHNNPVLKRALIDYLE
                     RDGVTHGLDMSTSAKRAFLQTFQDLVLRPRDLPYKVMFPGPTGTNAVESALKLARKVKG
                     REAIVSFTNAFHGMSLGSLAVTGNAFKRAGAGIPLVHGTPMPFDNYFDGTVPDFLWFER
                     LLEDQGSGLNKPAAVIVETVQGEGGINVARPEWLRALAELCERQDMLLIVDDIQMGCGR
                     TGAFFSFEEAGITPDIVTVSKSISGYGLPMSLCLFKPELDVWEPGEHNGTFRGNNPAFV
                     TATAALESYWADGSAMEKQTRTRGEQVEQGLIAICEENLADVKEYRGRGLVWGMEFH"
     gene            5001..5405
                     /locus_tag="AQI70_RS00455"
                     /old_locus_tag="AQI70_00455"
     CDS             5001..5405
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     ectoine: ectoine_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337952.1"
                     /locus_tag="AQI70_RS00455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_00455"
                     /product="ectoine synthase"
                     /protein_id="WP_004002244.1"
                     /sec_met_domain="ectoine_synt (E-value: 2.7e-55, bitscore:
                     181.7, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIVRSFKDIEGTERHVKSASGTWESKRIVLAKEKVGFSLHETILY
                     AGTETSMWYANHIEAVVCVEGEAELTDHETGRTYAITPGTMYLLDGHERHTLRIKEDFR
                     CLCVFNPPVTGREDHDENGVYPLLTEPEEV"
     gene            5413..6315
                     /gene="thpD"
                     /locus_tag="AQI70_RS00460"
                     /old_locus_tag="AQI70_00460"
     CDS             5413..6315
                     /EC_number="1.14.11.55"
                     /codon_start=1
                     /gene="thpD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PhyH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003976953.1"
                     /locus_tag="AQI70_RS00460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_00460"
                     /product="ectoine hydroxylase"
                     /protein_id="WP_004002243.1"
                     /sec_met_domain="PhyH (E-value: 1.8e-41, bitscore: 138.8,
                     seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAMTANVTDLYPSRGATEVSTPRQDPVVWGAPDTPGPITATDL
                     QAYERDGFLAIDQLITDDEVAVYRQELERLVTDPAIRADERSIIEPKSKEIRSVFEVHR
                     ISEVFASLVRDERVVGRARQILGSDVYVHQSRINVKPGFGASGFYWHSDFETWHAEDGL
                     PNMRTVSVSIALTENYDTNGGLMIMPGSHRTFLGCAGATPKDNYKKSLQMQDAGTPSDE
                     ALTKMASEYGIKLFTGRAGSATWFDCNCMHGSGDNITPFPRSNVFIVFNSVENAAVEPF
                     AAPVRRPEFIGARDFTPVK"
     gene            complement(6443..7493)
                     /locus_tag="AQI70_RS00465"
                     /old_locus_tag="AQI70_00465"
                     /pseudo=""
     CDS             complement(6443..7493)
                     /NRPS_PKS="Domain: Aminotran_5 (51-292). E-value: 3.3e-21.
                     Score: 67.5. Matches aSDomain:
                     nrpspksdomains_AQI70_RS00465_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004002242.1"
                     /locus_tag="AQI70_RS00465"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_00465"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /pseudo=""
                     /sec_met_domain="Aminotran_5 (E-value: 1e-17, bitscore:
                     60.2, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="METFESLVRAEFAPKNVYLNTASNGLLPARTVTALHRAVRMRAEG
                     TPLGPLYEDVEVVRASFARLAGVPVERVATGASVAEYGGLIAASLPAGAEVLTAEGDFA
                     SLVNPFHVRGDLKVRSVPLERLAESVRPDTALVAVSAAQSADGRVADLAAVREAARTHG
                     ARTYVDASQSAGWLPLEADAYDFVAAVGFKWLLGPHGAVFCVVPQDLGGLTPLLAGWVA
                     GEIPWDSCYGPVEDLARSARRFDISPSLFTYAGLRTSLELIEELGVAAIQAHDLALADR
                     FRTGLAALGHEPVPSPGSAIVSVPGLGDRQPELSRGHRGLQPRGQPARGLPPLQHPRGR
                     RPVARHPVRL"
     aSDomain        complement(6618..7340)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AQI70_RS00465_Aminotran_5.1"
                     /evalue="3.30E-21"
                     /label="AQI70_RS00465_Aminotran_5.1"
                     /locus_tag="AQI70_RS00465"
                     /protein_end="292"
                     /protein_start="51"
                     /score="67.5"
                     /tool="antismash"
                     /translation="YEDVEVVRASFARLAGVPVERVATGASVAEYGGLIAASLPAGAEV
                     LTAEGDFASLVNPFHVRGDLKVRSVPLERLAESVRPDTALVAVSAAQSADGRVADLAAV
                     REAARTHGARTYVDASQSAGWLPLEADAYDFVAAVGFKWLLGPHGAVFCVVPQDLGGLT
                     PLLAGWVAGEIPWDSCYGPVEDLARSARRFDISPSLFTYAGLRTSLELIEELGVAAIQA
                     HDLALADRFRTGLAALGHE"
     gene            complement(7593..8309)
                     /locus_tag="AQI70_RS00470"
                     /old_locus_tag="AQI70_00470"
     CDS             complement(7593..8309)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004002241.1"
                     /locus_tag="AQI70_RS00470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_00470"
                     /product="DsbA family oxidoreductase"
                     /protein_id="WP_062142437.1"
                     /transl_table=11
                     /translation="MRVEIWSDIACPWCYVGKARFEKALAAFPHRDQVEVVHRSFELDP
                     GRAKGDIQPVITMLTRKYGMSAAQAEAGEDNLGRLAAAEGLDYRTRGRDHGSTFDMHRL
                     LHLAKDKGRQDELLQTLYRANFAEERSVFAEGDERLVELAVAAGLDADDARKVLADPDA
                     YADDVRADEREAARLGATGVPFFVLDRKFGVSGAQPAEVFEQALTQAWGERSPLRLVDR
                     GDAEACGPDGCAVPQR"
     gene            complement(8397..8867)
                     /locus_tag="AQI70_RS00475"
                     /old_locus_tag="AQI70_00475"
     CDS             complement(8397..8867)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018545806.1"
                     /locus_tag="AQI70_RS00475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_00475"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_062142439.1"
                     /transl_table=11
                     /translation="MIRTVLPAEVEDIVALHARARATYYPDGLPQDGIDWRSAWQSAIA
                     LPDGHVLCVVEKGRIIGLASFRTPEGAPADTVKLFQFHVDPDHWRSGVGTALHAACVEE
                     WKADGKRTAVLDVHVDNRRAQAFYTRLGWLPDPENPPAEGHHHLFLRFCASA"
     gene            complement(8926..>9408)
                     /locus_tag="AQI70_RS00480"
                     /old_locus_tag="AQI70_00480"
                     /pseudo=""
     CDS             complement(8926..>9408)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004002239.1"
                     /locus_tag="AQI70_RS00480"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_00480"
                     /product="helix-turn-helix domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="TDYGAAVANEVARLALVAPVRPGGQTQFTQTPLPPERGNACADTR
                     GWAMRNLDKPLTLTDLARHAGVSVRTLTRRFHAESGVSPLQWLLHQRIERAKELLETTA
                     LPMDQVARACGLGTADSLRGHLVRRTGLTPSAYRAQFSRLGSPTGTGGAEATSSVA"
     gene            <9394..9795
                     /locus_tag="AQI70_RS00485"
                     /old_locus_tag="AQI70_00485"
                     /pseudo=""
     CDS             <9394..9795
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152076.1"
                     /locus_tag="AQI70_RS00485"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_00485"
                     /product="MFS transporter"
                     /pseudo=""
                     /transl_table=11
                     /translation="GAVVGRHGARLPMLVGQGLAVVGLLGLLYVDTGTPAVLVALLLVP
                     MALGCALTVPPLTAAMLDAVPAERAGLAAGVLNAARQMAGALGIAVFGALVSGGFVAGM
                     RLSLGISAALLVVTGLLSFRLAGPSASSA"
     gene            complement(9755..10363)
                     /locus_tag="AQI70_RS00490"
                     /old_locus_tag="AQI70_00490"
     CDS             complement(9755..10363)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016436202.1"
                     /locus_tag="AQI70_RS00490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AQI70_00490"
                     /product="DUF1349 domain-containing protein"
                     /protein_id="WP_062142442.1"
                     /transl_table=11
                     /translation="MDVELPELPFLLRTYGPDGHWSYEDGILSGWAGPRQDRFVPPTGE
                     ALDPASDAPRLLGAPEGDFQLIARVTVGFAAAFDAGVLYVHVGDRAWAKLCLEYSPDVP
                     IVCTVVTRGHSDDANSFTVEGSSVWLRVSRTGRAFAFHASRDGERWTFVRLFTLGDEKE
                     SDAALVGFMAQSPMGEGCVVTYDHIEFRPNWPKDLRDGS"
ORIGIN
        1 gggccgtacg aggtacccaa cgtccggatc gagggctggg gcctgtacac caacaacccg
       61 ccgtgcggcg cgatgcgcgg cctcggggcg gtgcagccgg cgttcgccta cgagctgcag
      121 atggacaagc tcgccacggc gctcggcatg gacccggtgc ggctgcgtca gctcaacgcc
      181 gtcgaagagg gctcgaccat gcacaccggg caggtcctcg actatccggc gccggtcgcc
      241 gagctgctgg aacgcctcga aaagctgccg ctgccaccgg agaaccggcc cgggccgagg
      301 gacatccgga ccctgccggg cggcctgtcc aacaccacgc acggcgaagg cgtcgtccgg
      361 ggcgtcggct acagcgtgat catcaagaac gtctcctacg ccgaaggcgt cgacgactac
      421 tccacggcgc gggtgcggct ggaggtcatc ggcggcgaac cggtggcgat ggtgcacacc
      481 gcggcggccg aggtcggaca gggcctgatc acggtgcagc agcagatcgc gcgcagcgaa
      541 ctcggcgtgg aacgggtgaa catccacccg gccgacacca acgtcggtga cgccgggtcg
      601 agttcggcct cccgccagac ctacatcacc ggcggcgccg tccggaacgc gtgcgaagcc
      661 gtccgcgcgg cggtcttcga ccgggtcgcc cagcggttcg gcgaggaccc cgcggcgctc
      721 tcgctctccg gcggcaaggt cgtctccgcg gccaccggct tcgtcgccga cctcgtcgac
      781 gtcctcggcg acgacgcgat cgaggagacc agggagtacc accacctgcg gacgtacgag
      841 atggacccgg tgaccggaca gagcccgcgg gtgcacgtcc agcacgcctt cgccgcgcac
      901 cgcgccgtgg tggaggtcga caccgagctg ggcctggtca aggtggtcca gctggactgc
      961 gcccaggacg tcggcaaggc catcaacccg gacgccgtcg tcgggcagat ccagggcggc
     1021 tccacacagg gcctcggcct tgccgtcatg gaggagatca aggtcgaaga cggcaagatc
     1081 cgcaacccgt cgttcaccga ctacctgatc ccgaccatcc tggacacgcc gcccatgacg
     1141 gtggacgtga tcgaaagggc cgacccgcac gccccctacg gcgtgcgtgg cgtcggcgaa
     1201 ccgcccacca tctccgccac cccggcgatc gtgaacgcca tccgcaacgc cacgggcctg
     1261 aacctcaccc acaccccggt cacaccggag cagctctgcg ggctctagcc gcgacgacct
     1321 cccgccggtg ccgcccgacg gcgctgaccc gacggcggca cccgtgggcc ctcgaacacc
     1381 caccctctcc cgaaggagtg accgtgacca cgcacacgca ggaaacgagt gtccaggagt
     1441 tcgagcgggc ctggatggaa aaggcgatca ggctggccac ccacagcgtg acggacggcg
     1501 gcggtccgtt cggcgcgctg gtcgccaagg acggcgcggt cgtcgcgatc gggcacaacc
     1561 aggtcaccgc gaccctggac ccggcggcgc acgccgaggt gagcgcgatg cgggccgcgt
     1621 gcagggaact cgacaccttc tcgctcgacg gctgtgtcct gatcacgtcg tgcgagccgt
     1681 gtccgatgtg cctgtccgcc gcactgtggg cgcgagtcga ccgggtcgtc tactgcgccg
     1741 accggcacga tgccgcggtg gccggcttcg acgaccgcag gttctacgac ctgttcgaga
     1801 agaggcccca gtcgatgtgg ccgatggcgg tcgagcgact ggacctgccg aaccgcacgg
     1861 cgccgttcga cgcgtggctg gccaagtcgg atcgcgtcga ctactgacga ggagctccgg
     1921 acaccgtccg tgccgaggtc cacgccccgg tggagttgaa cgggtgagtg cgggaagccg
     1981 tcccggccga cggccctcgt actgctgcgg cacggtgaga cgccgctgac acctcagaag
     2041 cggttctccg gcagtggcgg ctcggatccg ccgctgccgg aggccgcgtg gcggcaggcc
     2101 gggggcgacc gcgccacggc cggccgcccc gcggtggcgg gcaggtgatc gtcgccccgc
     2161 cgccgcggcg ctgccgggag gcgggctgcc ggcgcggcat gcggagtcga cggtgctggt
     2221 cgtctcgcac gcgccttccg tgggcgaggg cttccgccgt ggcctcgcct ccccgccggt
     2281 gatccgaggc cgagtgcaag actggcggca tgacgtccga tgcgcccctc accctccccg
     2341 acggccgccc cgtccccctc ctgaccggcg acgagcgccc catgctggaa agctggctgg
     2401 acttccaccg cgccaccctg gaactcaagt gcgccgggct ggacgacgcg cagttacgac
     2461 ttgcctccgc cgagccctcc gagctgacgt tgctcgggct ggtgcagcac ctcgccgagt
     2521 gtgagcggaa ctggttccag cgggtggtgg gtggactcga cgtgccgccg gtgtacgggg
     2581 agaagagcgg gtactcgctc gatcccgggc ggggtgtcga cgaggcgctc gcggtgtggc
     2641 gccgggagat cgcgcggggc cgggaggtgt gcgcggggcg gtcgctggac ggcgtggggc
     2701 ggatcgccga cgggcccatg gccggcgtgg aggtcagtct gcgctgggtg ctcatccaca
     2761 tgatcgagga gtacgcgcgg cacaacggcc acgccgacat tctgcgggag cgtatcgacg
     2821 gcgttaccgg cgcctgaatt caacgtaatt ccgcaattcc ttttccgggc agcttcccat
     2881 cctcttctgc ccgctttccc gggtcctaaa cgcaaagatt ccgcgaacgc caaccggagt
     2941 aattcgggca gatctcgtga gagttacatg gctgtgacgc gttccacatc gcatcccttt
     3001 tgtgcggtat taaccgggca aaatcgggcg attcacggct gtcacgcccc acccttcacg
     3061 cccgcgtgat aacacacctc gcctccatat gtaacccctc acggccatgc aatttcgaat
     3121 ttccctcggt aaattcaatc cgcatgactg ccgcacaagc agacctgcaa atcgaccgtc
     3181 cggcggtggc cgacggggcc gcgctgtggc gtattgccag agactcgaaa gccctcgacc
     3241 tcaactcgtc gtacagctat ctgctgtggt gccgcgactt cgccggcacg tcggccgtcg
     3301 cgcgtgacga gcgcggggag ccggtcggct tcgtcaccgg ctacgtacgg ccggaacgtc
     3361 cgcacaccct gctcgtctgg caggtggccg tggacggcgc gtaccgcgga cgcgggatcg
     3421 ccgccaggct gctcgacggg ctcgtcgcac gggtcggcgg cgagtacggc atcacgagcg
     3481 tggagacgac catcacgccc ggcaacaccg cctcggagcg gctgttcggt tccttcgccg
     3541 agcggcacgg cgcccgggtc gagcgtgagg tgctgttcga caccggcctg ttccccgacg
     3601 ggccgcacga ccccgaagtc ctctaccgca tcggtcccct ctccctctga cctcccccca
     3661 cgcaacgagg agcgattcgt cgtgaccatc acccagcccg acctcagcgt cttcgagacc
     3721 ctggagtccg aggtgcgcag ctactgccgc ggctggccca ccgtcttcga ccgtgcgcga
     3781 ggcagccgca tgtacgacga ggacggccac gagtatctgg acttcttcgc cggggccggc
     3841 tcgctgaact acgggcacaa caacccggtc ctgaagcggg cgttgatcga ctacctggag
     3901 cgggacggcg tcacgcacgg gctcgacatg tccaccagcg ccaaacgggc cttcctgcag
     3961 accttccagg acctggtgct gcgcccgcgc gacctgccgt acaaggtcat gttccccgga
     4021 cccaccggca ccaacgccgt ggagtccgcg ctgaagctgg cccggaaggt gaaggggcgc
     4081 gaggccatcg tgtccttcac caacgccttc cacggcatgt ccctcggctc cctcgccgtc
     4141 accggcaacg cgttcaagcg cgccggcgcc gggatcccgc tcgtgcacgg cacgcccatg
     4201 ccgttcgaca actacttcga cggcacggtc ccggacttcc tgtggttcga gcggctcctg
     4261 gaggaccagg gctcggggct caacaagccc gccgccgtga tcgtcgagac cgtgcagggc
     4321 gagggcggca tcaacgtcgc gcgtcccgag tggctgcggg cgctcgccga gctgtgcgag
     4381 cggcaggaca tgctgctcat cgtcgacgac atccagatgg gctgcgggcg cacgggtgcc
     4441 ttcttctcct tcgaggaggc gggcatcacc ccggacatcg tcacagtgtc caagtccatc
     4501 agcggctatg gcctccccat gtcgctgtgc ctgttcaagc ccgagctgga cgtctgggag
     4561 ccgggcgagc acaacggcac cttccgcggc aacaaccccg ccttcgtcac ggccaccgcc
     4621 gccctggagt cgtactgggc cgacggttcc gcgatggaga agcagacccg gacccgcggc
     4681 gagcaggtcg agcagggcct gatcgccatc tgcgaggaga acctcgccga tgtgaaggag
     4741 taccggggcc gcgggctggt gtggggcatg gagttccacg acaaggagcg ggctggccgc
     4801 gtcgcccggc gcgccttcga actcggcctg ctcgtggaga cgtccggccc ggagagcgag
     4861 gtcgccaagc tgctgcccgc cctcaccatc accccggacg agctcgacga gggcctcagc
     4921 atcctggccc gcgccgtccg cgaaaccgcc tgaccggccg ggaaaccggc acaccaccac
     4981 ctaggaggca tcgcagcacc gtgatcgtcc gttcgttcaa ggacatcgaa ggcaccgagc
     5041 gccatgtgaa atcggcgtcc ggcacctggg agagcaagcg catcgtcctc gccaaggaga
     5101 aggtcggctt ctccctgcac gagacgatcc tgtacgcggg tacggagacg tcgatgtggt
     5161 acgcgaacca catcgaggcc gtcgtctgcg tcgagggtga ggccgagctg accgaccacg
     5221 agaccgggcg gacgtacgcg atcacgcccg ggaccatgta cctcctggac ggccacgaga
     5281 ggcacacgct gcggatcaag gaggacttcc gctgcctctg tgtcttcaac ccgccagtga
     5341 ccggccgtga ggaccacgac gagaacggcg tgtacccgct gctcaccgag cccgaggagg
     5401 tgtgagaaac ccatgaccac cgccatgacc gcaaacgtca ccgatctcta tcccagccgc
     5461 ggcgccaccg aggtgtcgac cccgcgccag gaccccgtcg tctggggcgc ccccgacacc
     5521 cccggcccga tcacggccac cgacctccag gcgtacgagc gcgacggctt cctcgccatc
     5581 gaccagctca tcaccgatga cgaggtggcc gtctaccggc aggagctgga gcgcctggtc
     5641 accgacccgg cgatccgcgc ggacgagcgg tcgatcatcg agccgaagtc caaggagatc
     5701 cggtccgtct tcgaggtgca caggatcagc gaggtgttcg cgagcctcgt gcgcgacgag
     5761 cgggtggtcg gccgggcgcg gcagatcctc ggctcggacg tgtacgtcca ccagtcgcgg
     5821 atcaacgtca agccgggctt cggggccagc ggcttctact ggcactccga cttcgagacc
     5881 tggcacgccg aggacggtct gccgaacatg cggacggtgt cggtctcgat cgcgctgacc
     5941 gagaactacg acaccaacgg cgggctcatg atcatgcccg gctcgcacag gaccttcctg
     6001 gggtgtgcgg gcgccacgcc gaaggacaac tacaagaagt ccctccagat gcaggacgcg
     6061 ggcacgccgt ccgacgaggc gctgaccaag atggcctccg agtacggcat caagctcttc
     6121 acgggcaggg ccggttcggc gacctggttc gactgcaact gcatgcacgg ctccggggac
     6181 aacatcacgc cgttcccgcg cagcaacgtg ttcatcgtgt tcaacagcgt ggagaacgcg
     6241 gccgtcgagc ccttcgcggc tccggtacgg cggcccgagt tcatcggcgc gagggacttc
     6301 acgccggtga agtgaccccc tgcggtgaag tgcccccggc ggggaggtga cctcacttcg
     6361 gtgaggcgcc ctcacgacca cgacggcgac gcggcccgct ccgtacgttc cgtacggcgg
     6421 ccgcgtcgcc gcgttgcgtg gttcaggcgg acagggtgtc gagcaaccgg tcgacgtcct
     6481 cgggggtgtt gtagaggtgg aaggccgcgc gcaggttgcc cgcgcggttg gagacctcga
     6541 tgcccgcggc tcaactcggg ctggcggtcc ccgagtccgg gcacggacac gatcgccgag
     6601 ccgggcgagg gcaccggttc gtggccgagg gcggccaggc ccgtacggaa acggtcggcc
     6661 agggcgaggt catgtgcctg gatggcggcc acgccgagct cctcgatcag ctccagggaa
     6721 gtgcgcagcc cggcgtaggt gaagaggctg gggctgatgt cgaagcgccg tgcggagcgg
     6781 gcgaggtcct cgaccgggcc gtagcagctg tcccacggga tctccccggc gacccagccg
     6841 gcgagcagcg gggtcagccc gccgaggtcc tgcgggacga cacagaacac ggccccgtgc
     6901 gggcccagga gccacttgaa gccgacggcg gcgacgaagt cgtacgcgtc ggcctccagc
     6961 ggcagccaac cggcggactg ggaggcgtcg acgtaggtgc gcgccccgtg cgtccgggcc
     7021 gcctcgcgca ccgcggccag gtcggcgacg cggccgtcgg cggactgcgc ggcgctgacc
     7081 gcgacgagcg cggtgtccgg gcggacggac tcggcgaggc gttccagcgg gacggaacgc
     7141 accttgaggt cgccgcggac gtggaagggg ttcaccaggg aggcgaagtc gccctcggcg
     7201 gtgaggactt cggccccggc gggcagcgag gcggcgatca gcccgccgta ctcggcgacc
     7261 gaggccccgg tcgcgacgcg ctcgacgggc acgccggcca gcctcgcgaa ggaggcgcgg
     7321 acgacctcca cgtcctcgta cagggggccc agcggtgtgc cctcggcccg catccgcacg
     7381 gcccggtgca gggcggtcac ggtgcgggcc ggcagcaggc cgttgctcgc ggtgttgaga
     7441 tagacgttct tcggggcgaa ctcggcgcgg acgaggctct cgaaggtctc catgggtcca
     7501 ctgtgggccc tcggcccctc atggtccatt gcgattttct acgtggtttc gccaaggaac
     7561 gcttatggat ccgccccgac ctgcacactc gctcagcgct gcggcaccgc gcacccgtcg
     7621 ggaccgcacg cctccgcgtc accccggtcg acgaggcgca gcggtgaccg ctcgccccac
     7681 gcctgtgtga gcgcctgctc gaagacctcg gcgggctggg cgccggagac gccgaacttg
     7741 cggtcgagga cgaagaacgg cacgccggtg gcgccgagcc gggcggcctc gcgctcgtcg
     7801 gcgcggacgt cgtcggcgta ggcgtccggg tcggcgagga ccttgcgggc gtcgtcggcg
     7861 tcgaggccgg cggcgacggc cagttccacg agccgctcgt cgccctcggc gaagacggac
     7921 cgctcctcgg cgaagttcgc ccggtagagc gtctggagca gttcgtcctg ccggcccttg
     7981 tccttggcga ggtgcaggag ccggtgcatg tcgaaggtgc tgccgtggtc gcggccccgg
     8041 gtgcggtagt ccaggccctc ggcggcggcg agccggccca ggttgtcctc accggcctcg
     8101 gcctgcgccg cgctcatgcc gtacttcctg gtgagcatgg tgatcacggg ctggatgtcg
     8161 cccttggcgc gcccgggatc cagctcgaac gagcggtgca ccacctcgac ctggtcgcgg
     8221 tgcgggaagg ccgccagcgc cttctcgaag cgggccttgc ccacatagca ccaggggcag
     8281 gcgatgtcgc tccagatctc gacgcgcatg tctgtggctc tctccaggtc gaacgggata
     8341 cggagactcc ctccggtgac tatatgaacc ttcaagcagc ccggttcatt ccccggtcac
     8401 gcagaagcgc agaagcgcag aaagagatgg tgatgaccct cggcgggcgg gttctcgggg
     8461 tcgggaagcc agccgagacg ggtgtagaag gcctgggcgc gccggttgtc gacgtgcacg
     8521 tccaggacgg ccgtgcgctt gccgtcggcc ttccactcct cgacgcaggc cgcgtgcagg
     8581 gcggtgccga cgccggaacg ccagtggtcg gggtcgacgt ggaactggaa gagcttgacc
     8641 gtgtccgcgg gggcgccctc cggggtgcgg aaggaggcga ggccgatgat gcggcccttc
     8701 tccacgacgc acagcacatg cccgtccggc agggcgatgg cgctctgcca ggccgagcgc
     8761 cagtcgatgc cgtcctgcgg cagcccgtcg ggatagtagg tcgcccgggc gcgggcgtgc
     8821 agggcgacga tgtcctcgac ctcggcgggc aggacggtac ggatcacgcg gccttcgctc
     8881 actcggtcac tcggtcactc ggtcactcgg tcactcggtc actgatcatg caacggagga
     8941 cgtggcctcg gcgcccccgg ttccggtcgg gctccccagc cggctgaact gggcccggta
     9001 ggcactcggc gtcagccccg tccggcggac cagatgcccc cgcagcgagt cggccgtgcc
     9061 cagaccgcag gcgcgggcca cctggtccat gggcagggcg gtggtctcca gcagctcctt
     9121 ggcgcgctcg atgcgctggt ggagcagcca ctgcagaggg ctcaccccgc tctcggcatg
     9181 gaagcggcgg gtgagggtgc ggacgctgac gccggcgtgg cgggccaggt cggtgagggt
     9241 gagcggcttg tcgaggttgc gcatggccca gccgcgggtg tcggcgcagg cgtttccgcg
     9301 ctcgggcggc agcggggtct gggtgaactg ggtctggccg ccgggccgta caggggcgac
     9361 gagggcgagc cgggccacct cgttggcgac ggcggcgccg tagtcggtcg ccacggcgcg
     9421 cggctgccca tgctggtggg gcagggcctg gccgtcgtag ggctgctggg gctgctgtac
     9481 gtcgacaccg gcacgcctgc ggtcctggtg gccctgctcc tcgtccccat ggcgctgggc
     9541 tgcgcgctga cggtgccgcc gctgacggcg gcgatgctgg acgccgtacc cgccgaacgg
     9601 gcgggcctgg cggccggggt gctcaacgcg gcccggcaga tggccggggc gctggggatc
     9661 gcggtcttcg gggcgctggt ctccggcggt ttcgtggccg gcatgcgcct gagcctgggg
     9721 atcagcgcgg ccctgctcgt ggtgacgggc ctgctcagct tccgtctcgc aggtccttcg
     9781 gccagttcgg cctgaactcg atgtggtcgt aggtcacgac acacccctcc cccatcggcg
     9841 actgcgccat gaagccgacc agggcggcgt cgctctcctt ctcgtcgccc agggtgaaca
     9901 ggcggacgaa ggtccagcgc tcgccgtcgc gggaggcgtg gaaggcgaag gcgcggccgg
     9961 tgcggctgac tcggagccac accgaactgc cttccacggt gaaggagttg gcgtcgtcgg
    10021 agtgcccccg ggtgaccacc gtgcagacga tgggcacgtc cggggagtac tccaggcaga
    10081 gcttggccca ggcgcggtcg ccgacatgga cgtagagcac tccggcgtcg aaggcggcgg
    10141 cgaacccgac ggtgacccgg gctatcagct ggaagtcccc ttccggagca cccaggagcc
    10201 gtggcgcgtc ggaggcgggg tccagggcct ccccggtggg cggcacgaac cggtcctgcc
    10261 ggggcccggc ccatccggag aggatgccgt cctcgtagga ccagtggccg tcggggccat
    10321 aggtacggag caggaaaggc agttcgggaa gttccacgtc catcgccaca gtgtctcagt
    10381 agatctctcg cagcaccttt ggagc
//
