LOCUS       NZ_LNBE01000004        13112 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces roseifaciens strain MBT76 scaffold_4, whole genome
            shotgun sequence.
ACCESSION   NZ_LNBE01000004
VERSION     NZ_LNBE01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseifaciens
  ORGANISM  Streptomyces roseifaciens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 3642602)
  AUTHORS   Wu,C., Zhu,H., van Wezel,G.P. and Choi,Y.H.
  TITLE     Metabolomics-guided analysis of isocoumarin production by
            Streptomyces species MBT76 and biotransformation of flavonoids and
            phenylpropanoids
  JOURNAL   Metabolomics 12, 90 (2016)
   PUBMED   27073352
REFERENCE   2  (bases 1 to 3642602)
  AUTHORS   Wu,C., Zhu,H., van Wezel,G.P. and Choi,Y.H.
  TITLE     Metabolomics-guided analysis of isocoumarin production by
            Streptomyces species MBT76 and biotransformation of flavonoids and
            phenylpropanoids
  JOURNAL   Metabolomics 12, 90 (2016)
   PUBMED   27073352
REFERENCE   3  (bases 1 to 3642602)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     The complementarity of genome-mining and NMR metabolic-profiling
            facilitates lead-finding
  JOURNAL   Unpublished
REFERENCE   4  (bases 1 to 3642602)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     The complementarity of genome-mining and NMR metabolic-profiling
            facilitates lead-finding
  JOURNAL   Unpublished
REFERENCE   5  (bases 1 to 3642602)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2015) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
REFERENCE   6  (bases 1 to 3642602)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2015) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.06
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001445655.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 03:28:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,528
            CDSs (total)                      :: 7,450
            Genes (coding)                    :: 7,245
            CDSs (with protein)               :: 7,245
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 205
            CDSs (without protein)            :: 205
            Pseudo Genes (ambiguous residues) :: 0 of 205
            Pseudo Genes (frameshifted)       :: 77 of 205
            Pseudo Genes (incomplete)         :: 168 of 205
            Pseudo Genes (internal stop)      :: 20 of 205
            Pseudo Genes (multiple problems)  :: 56 of 205
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:37:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3241709
            Orig. end                         :: 3254821
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LNBE01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13112
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="9"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..13112
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13112
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8112](+)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8112
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     misc_feature    78..91
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.18"
                     /tool="antismash"
     gene            complement(476..1336)
                     /locus_tag="AS857_RS31685"
     CDS             complement(476..1336)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AS857_RS31685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_079110762.1"
                     /transl_table=11
                     /translation="MRRRPVRLFPPAALVTVLLCTSVTPAATAADDDRPWSAAPAPAGT
                     EAPGPDDRASFYLEGAPGTVFTDKLSVVNPADRERSFALRGAGTWISFPRQQVRVPART
                     RANVPVRVTVPGDAEPGDHSGAVVVSGEGREVRVRLALRVSGGPALPALAVENVRVSGA
                     GTGGAVIRYALVNRGNRTLTPRLAIRADGVFGTVLRRTVADAPAELAPGRVVRRVERWP
                     DAPRLDSVTVRVTAVAEGGVRASGSGSYTPVRWVLPVGGGVVLALAGGAVVLVRRRRRG
                     AGSGA"
     gene            complement(1357..2199)
                     /locus_tag="AS857_RS31690"
     CDS             complement(1357..2199)
                     /GO_component="GO:0009986 - cell surface [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016643551.1"
                     /locus_tag="AS857_RS31690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LPXTG cell wall anchor domain-containing protein"
                     /protein_id="WP_058046589.1"
                     /transl_table=11
                     /translation="MSHIPRRAAALAASLAGGAVLLGAPAAHAVTIDVDYACKTPIGDK
                     SAVSPIDIKGVADGGAYKLTMTFEKGVSSSPIELGKGAMKPSAVIKVGGADSGTVAVSG
                     PANTEPIPANTPIKISDLSGTYTPKKSGSVTFTASTLTIQALGTTTTCTPTNNPKPSLT
                     LDIKEPGGSSGGSSTGGSSTGGSSTGGSSTGGSTGGSATGGSGSGGASGGAASGGSSTG
                     GSATGGSSSTGGSTGGQLPQTGPADSAIALGTLGGTVLLTGVAGTLWLTRRRRAATTR"
     gene            complement(2380..2898)
                     /locus_tag="AS857_RS31695"
     CDS             complement(2380..2898)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061224.1"
                     /locus_tag="AS857_RS31695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_058046590.1"
                     /transl_table=11
                     /translation="MSTTRPCPPPGDPGPGANGAASSGALSPDGPSQGSRPGGMRRLHL
                     VGVSGAVPMSRDFTRQALHDWGWLPAIGADHRAAAEDVLLVVSELVTNACLHADGPEEL
                     RVSCTGKVLRLEVVDLGAGTPAPRTPHRAGRPGGHGMFIVQRLCLDWGVVRNESGAGKT
                     VWAELAAPG"
     misc_feature    complement(2918..2932)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.56"
                     /tool="antismash"
     misc_feature    complement(3111..3126)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     gene            complement(3155..3523)
                     /locus_tag="AS857_RS31700"
     CDS             complement(3155..3523)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019329970.1"
                     /locus_tag="AS857_RS31700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="STAS domain-containing protein"
                     /protein_id="WP_058046591.1"
                     /transl_table=11
                     /translation="MDRGMVGSASRGRLHVAVRRDGASAIVTPVGELDHHTADVLREPL
                     EAAIADGGARVVLDCSGLEFCDSTGLNVLLGARLQAEAAGGGIHLAAMQPVVARVFEIT
                     GAEAVFTVHDTLDAALAG"
     misc_feature    3606..3619
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.51"
                     /tool="antismash"
     misc_feature    3606..3620
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.49"
                     /tool="antismash"
     gene            3753..4676
                     /locus_tag="AS857_RS31705"
     CDS             3753..4676
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016326408.1"
                     /locus_tag="AS857_RS31705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_058047193.1"
                     /transl_table=11
                     /translation="MEETMSPRLDETRAEPRTASSAPLPQSPPEYSYSDLPGFPECDGT
                     GPTPPGEMAPHDARALSKTLFARLEALEEGTHEYAYVRNTLVELNLALVRFAAARFRSR
                     SEPMEDIVQVGTIGLIKAIDRFELSRGVEFPTFAMPTIIGEIKRFFRDTSWSVRVPRRL
                     QELRIDLAKARDELAQSLDRSPTVGELAGHLGLTKDEVVEGMAASNAYSASSLDAQPQD
                     DEAEGALSARIGYEDHDLEGVEYVAALKPMIAELPQRDRKILSLRFVANMTQSEIGEEL
                     GISQMHVSRLLGRTLVRLRRGLLSEE"
     gene            5001..6194
                     /locus_tag="AS857_RS31710"
     CDS             5001..6194
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642316.1"
                     /locus_tag="AS857_RS31710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_275477394.1"
                     /sec_met_domain="DAO (E-value: 3.1e-61, bitscore: 205.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGSGVVGAACAEALTRRGARVLVLDRGPLAAGTTACGEGNLLVS
                     NKAPGPGLALAQASLSRWPRLLAALREELGPGRAECEYEVKGGLVVATGEPEGAALCGF
                     AAAQRAAGVDARELAPGEAAAYEPHLTPAVRAAVHYPQDAQLQPVLAATSLLAAVRARG
                     GRIRTGVDVTGVETGRDGRAVGVRTSQGRIPCGAVVNACGPWAGEFAAAAGAPLPVVPR
                     RGTVLVTAPLPHGTVRHKVYDAGYAETARSEDAALQVAAVVEATQAGTVLIGSSRQRCG
                     FDGTLRAGVLGALARAAAQLFPVLGGVPVMRAYGGFRPYTPDHLPVVGEDPRHPGLWHA
                     TGHEGAGIGLAAATGELLAELWAGEPPHLDPEPFRVQRFGTARTTRTARFGRENGWH"
     gene            6185..>6430
                     /locus_tag="AS857_RS41690"
                     /pseudo=""
     CDS             6185..>6430
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020118955.1"
                     /locus_tag="AS857_RS41690"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="(2Fe-2S)-binding protein"
                     /pseudo=""
                     /sec_met_domain="Fer2_4 (E-value: 1.6e-23, bitscore: 80.2,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALTVYVDGERHRALPGQTVAALLLATGRRSWRTTRLGGRPRGVF
                     CGIGVCYDCLVVVNGLPDVRACRRELRDGDRVETQRG"
     gene            6619..8112
                     /locus_tag="AS857_RS31720"
     CDS             6619..8112
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468369.1"
                     /locus_tag="AS857_RS31720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_079110764.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.1e-23, bitscore:
                     81.5, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 2e-09, bitscore: 35.3,
                     seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAQPPLASSSASASATATASPLVVVVGAGPAGARAALSAARCDA
                     RVVLADSEERVGGRHHRQPAVAGGGPGASAAHPLEQAVATQPRITHLARATVWALEPGP
                     APGRHLVHLQQGPADDRGRPVRTLAADALVLCTGAFDRALPFPGWELPGVVTAGAAQAL
                     AEGQRTAPGGRAVVSGTGPFLLPVALSLLGVGAQVLGVYEAGNPARWLRSPAAALRDGG
                     PGRLAELGSYAVGLARRRVPYRTRHAVVAAHGRDRVEAVTVARLDAGWHPVAGSEQRIA
                     PVDAVCVGYGFLPQLELPLAAGCAVRGGHVVVDGRQATTVPGVYAAGELTGVAGAPAAA
                     AEGELAGLAAVADLAERPEAAEAGARLVPPSPARLAAAASRVRSGRRFARALARAHPVP
                     GGWRGWLREDTLVCRCEEVSYGELRDAVVARGADGMRALKLTCRAGLGACQGRICGRNT
                     AELAAAFLGSPVADPYAMDRRPLAHPVRLGDLAGPPAID"
     misc_feature    6637..6639
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8175..9833
                     /gene="hutU"
                     /locus_tag="AS857_RS31725"
     CDS             8175..9833
                     /EC_number="4.2.1.49"
                     /GO_function="GO:0016153 - urocanate hydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006548 - histidine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hutU"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014061230.1"
                     /locus_tag="AS857_RS31725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="urocanate hydratase"
                     /protein_id="WP_058046592.1"
                     /transl_table=11
                     /translation="MSGPRPVRAARGSRLSTLGWQQEAALRMLQNNLDPEVAEHPDKLV
                     VYGGTGKAARDWRSFDAMVRTLQTLKQDETMLVQSGRPVGVMQTHEWAPRVLLANSNLV
                     GDWANWEEFRRLEHLGLTMYGQMTAGSWIYIGTQGILQGTYETFAAVAAKKFDGTLAGT
                     ITLTAGLGGMGGAQPLAVTMNDGVAICIDCDPRAIDRRIEHRYLDVKADSLDHALQLAV
                     EARDARRPLSIGVLGNAAELVPQLLAMNAPIDIVTDQTSAHDPLAYLPVGVSFDDMATY
                     AAEKPADFTTRARESMARHVEAMVGFQDAGAEVFDYGNSIRGEAQLAGYTRAFDFPGFV
                     PAYIRPLFCEGKGPFRWAALSGDPADIHKTDKAILELFPENESLARWIKMAGERVHFQG
                     LPARICWLGYGERDKAGERFNDMVADGTLAAPLAIGRDHLDCGSVASPYRETEAMLDGS
                     DAIADWPLLNAMVNVASGASWVSIHHGGGVGMGRSIHAGQVTVADGTPLAGEKIRRVLT
                     NDPGMGVIRHVDAGYDIAESVAEDRGVRVPMREGE"
     gene            9830..11071
                     /locus_tag="AS857_RS31730"
     CDS             9830..11071
                     /GO_function="GO:0016813 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in linear amidines
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128509.1"
                     /locus_tag="AS857_RS31730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="allantoate amidohydrolase"
                     /protein_id="WP_058046593.1"
                     /transl_table=11
                     /translation="MSSPAAGEVKAGASFHEMWRDLASIGRDKDTAGYHRFAWSGADAD
                     CRAWFRAQAESRGLAYELDRNGNQWAWLGDPAAGDAVVTGSHLDSVPNGGAFDGPLGVV
                     SSFAALDELRARGAQPSRPLAVVNFGDEEGARFGLACVGSRLTAGQLSLDKAHALRDAE
                     GVSLPLAMERAGYDPEAIGPDPERLARIGAFVELHVEQGRALDLSDRAVGIASAIWPHG
                     RWRFDFHGEANHAGTTRIEDRRDPMLTYANTVLAARKKARLAGALATFGKVGVEPNGVN
                     AIPSLVRGWLDSRAADQETLDLVVAEIEKAAVERGERDGVDVRVTRESFTPVVEFEHAL
                     RDELGRILGGDVPVLGTGAGHDAGILSGAVPTAMLFVRNPTGVSHSPAETASEDDCLAG
                     VTALADVLEGLACR"
     gene            11068..12408
                     /locus_tag="AS857_RS31735"
     CDS             11068..12408
                     /EC_number="3.5.3.13"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017241228.1"
                     /locus_tag="AS857_RS31735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="formimidoylglutamate deiminase"
                     /protein_id="WP_107105749.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 6.2e-47, bitscore:
                     158.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAQTYWAEHALLDTGVEPGVVIETGTDGRIKAVRRGAAAPPQGA
                     VTLRGLTLPGLANAHSHAFHRALRGATQAGEGTFWTWRDVMYRVADNLTPDSYFALARA
                     AYAEMALAGITSVGEFHYVHHLAGGARYDNPNAMGEALIAAAAEAGIRITLLDACYLSS
                     GFGAEPNKHQRRFSDGTAERWAERVSALKGDDNTRIGAAIHSVRAVPAEQLATVAAWAQ
                     ERDAPLHLHLSEQTAENDACVEAHGFTPTALLSHHGVLGPRTTAVHATHLTPGDIRLLG
                     HSGTGVCMCPTTERDLADGIGPARALQEAGSPLSLGSDSHAVIDLLEEARAMELDERLH
                     SRTRGHWTAVQLLRAATADGHAALGWDGAGRIERGALADFTAVALDSVRTAGQPYALAA
                     ETAVFAASAADVRDTVVGGRHIVREGAHQLVAHVPAALAESIAAVRG"
ORIGIN
        1 gtcacggtgg ccacgtgcac cacacaaggg caaggcgtgg gcggctcgac aacaacaagc
       61 tcccgccgaa agaccccgtc acgctccgta gtaacagtgc gcccctccgc gttaacgcag
      121 tcgttggtgc cccccaccat gttctgcccg cacaccagca gagtgagcaa ggcccgcgac
      181 cgccaccctt cccccctgac gaccacggtg ctgcccttac cggcctccgc ccgatccagc
      241 gagagacgag gcccatcggc agcagccgct cccgcagcgg gcaacagggc gacgaggagg
      301 accagcagca gaagaacgac ggcggaggcg ccggggccgc aggggcaggg ccctggacgc
      361 tgacgtgtat gtgcggcgcc cggcgcgggg tgcgcatgcg gcagggcaga gggcgccgta
      421 aatagacggt ccagggccct gccccggagg ccccggcgcc ggaccacgac gcgcctcatg
      481 cgccgctccc cgcaccgcgg cgccgccgtc gcaccagcac caccgcccca cccgcaagcg
      541 ccagcaccac cccgccaccc accggcagaa cccaccgcac gggcgtgtac gagccggacc
      601 cgctggcccg taccccgccc tccgcgacag cggtcacgcg caccgtcacc gagtccagcc
      661 gcggcgcatc cggccaccgc tccaccctcc gcaccacccg ccccggcgcc agctcggccg
      721 gcgcgtcggc gaccgtgcgg cggaggaccg tgccgaaaac cccgtcggcg cggatggcga
      781 gccgcggggt cagcgtcctg ttgccacggt tgaccagggc gtaccggatg accgcgccgc
      841 ccgtgcccgc gccgctcacc cgtacgttct cgacggcgag cgccggcagc gccggtcccc
      901 cgctgacacg cagggccagc cgcacccgca cctcccgccc ctccccgctc acgaccaccg
      961 cgccggagtg gtcgccgggc tccgcgtcac cggggaccgt cacgcgcacg ggcacgttcg
     1021 cccgggtgcg ggcgggcacc cgtacctgct gccgggggaa ggagatccag gtcccggcgc
     1081 cccggagggc gaaggagcgc tcgcggtccg cggggttgac cacggacagc ttgtcggtga
     1141 agaccgtgcc gggggcgccc tccaggtaga acgacgcgcg gtcgtccggt ccgggcgcct
     1201 ccgtaccggc gggagcgggc gcggccgacc acggccggtc gtcgtcggcg gcggtggctg
     1261 ccggggtgac ggaggtgcag agcagcaccg tcacgagggc ggccggcggg aagagacgga
     1321 cgggacgacg gcgcacaggc ggccccttca tgcgtgtcag cgcgtggtcg ccgcccggcg
     1381 ccgccgggtc agccagagcg tgcccgcgac gccggtgagg aggacggtgc cgccgagggt
     1441 gccgagggcg atggcggagt cggcgggccc ggtctgggga agctgaccgc ccgtggaacc
     1501 cccggtggag gaggaaccac cggtggcaga accgccggtg gaggacccac ccgaggcggc
     1561 cccgccggaa gccccgccgg aacccgaccc acccgtagcg gaacctccgg tggacccacc
     1621 cgtagaggac ccacccgtgg aggacccacc ggtggaggac ccaccggtgg aggacccacc
     1681 ggaactcccg ccgggctcct tgatgtcgag cgtcagcgac ggcttggggt tgttcgtcgg
     1741 cgtgcaggtg gtggtcgtgc ccagcgcctg gatggtcagc gtggaggcgg tgaacgtcac
     1801 gctgccgctc ttcttcgggg tgtacgtccc cgacaggtca ctgatcttga tcggggtgtt
     1861 ggccggtatc ggctccgtgt tggcgggccc ggagacggcg accgtcccgc tgtccgcgcc
     1921 gcccaccttg atgacggcgc tcggcttcat cgcgcccttg ccgagctcga tggggctgga
     1981 ggagacgccc ttctcgaagg tcatggtcag cttgtacgca ccgccgtccg cgacgccctt
     2041 gatgtcgatg ggcgagacgg cgctcttgtc tccgatgggg gtcttgcacg cgtagtcgac
     2101 gtcgatcgtc accgcgtgcg cggccggagc gcccagcagg acggccccgc cggccaggga
     2161 cgcggcgagg gcggctgcgc ggcgtgggat gtgggacacc tctggttccc ctctcgtccg
     2221 gtgccgcagc cgagcagagc cgagctgagc ccagccgagc tgacggcaca tcagatcggg
     2281 cgcagacagt acgccgggga ccttgaggaa ggaagagaaa ggaagagaag ggaggaagga
     2341 agggacgcgg gagagagaag agaaggggga gccagaggcc tagcccggcg cggccagctc
     2401 cgcccacacc gtcttcccgg ccccgctctc gttccgcacg acgccccagt ccaggcagag
     2461 cctctgcacg atgaacatcc cgtgcccgcc gggccgcccc gcgcggtgcg gcgtgcgcgg
     2521 tgcgggcgtc cccgcgccga ggtcgacgac ctccaggcgc agcaccttgc ccgtgcagct
     2581 cacgcggagc tcctcggggc cgtcggcgtg caggcaggcg ttggtgacca gctcggagac
     2641 gacgagcagg acgtcctcgg cggccgcgcg gtggtccgcg ccgatcgcgg ggagccagcc
     2701 ccagtcgtgg agcgcctgcc gggtgaagtc acgcgacatg ggcacggcgc cgctgacccc
     2761 gacgaggtgc agccggcgca tcccgccggg ccgggacccc tgcgaaggcc cgtccggcga
     2821 cagcgcaccg gaggaggcgg cgccgttcgc ccccggaccg gggtcgcccg gcggagggca
     2881 cggccgggtg gtgctcatca gcgcttcacc tcaccgattc accgattcag aacggaacga
     2941 agggacggac gggtacctgg ataccttgat cgcggctacc tggcacatgg aacggattca
     3001 gcagactcct gcccgaccga atcgtgagaa cacccacttc ttcggtgccg atcctgtgat
     3061 gcatgcaact ggtgcctgcg aacccacgcc gaaggagccc ggccgaccgg gtgacgactg
     3121 agtaacgcac agggaaaggc gggggcgcca ggggtcagcc ggcgagggcc gcgtcgaggg
     3181 tgtcgtgcac cgtgaagacg gcttccgcgc cggtgatctc gaagacccgg gcgaccacgg
     3241 gctgcatcgc agccaggtgg attccgccgc ctgcggcctc ggcctgcagc cgggcgccca
     3301 gaagcacgtt caggccggtc gagtcgcaga actccagacc ggagcaatcg aggaccacgc
     3361 gtgcgccgcc gtcggcgatg gcggcctcga ggggctcgcg cagtacgtcc gccgtgtggt
     3421 gatcgagctc acccaccggc gtcacgatcg cgctcgcccc gtcccgccgg acggctacat
     3481 gcagccggcc cctgcttgcg ctgccgacca tcccgcgatc catgcgcatc ccttctcggt
     3541 gtgcctgcgt ggcgctccca gaacactacg ccttccctac ggcgtccggt agccgaaggt
     3601 ccggcattat tcacatatag ggacatcacg cacttgcggt gcacgggtga agacaggtag
     3661 ggctagtagg acgacatcca ccacggacgg ctttggaggc gccgctcacc gcagcacgac
     3721 gcgacggcat cggcagccat atgccgagaa tgatggagga gaccatgtca ccccggctcg
     3781 acgaaacgcg tgcggaaccg cgtacggcgt cgtcggcacc cctgccccag tccccgcccg
     3841 agtattccta ttccgacctt cccgggtttc ccgagtgcga cgggaccggc cccacgcccc
     3901 ccggcgaaat ggcgccgcac gacgcacgtg ccctgtccaa gacgctcttc gcccgcctgg
     3961 aggcgctcga agagggcacg cacgaatacg catacgtacg caacaccctg gtcgaactga
     4021 acctcgccct cgtgaggttc gccgccgccc ggttccgctc ccgcagcgag ccgatggagg
     4081 acatcgtcca ggtcggcacg atcggcctca tcaaggccat cgaccgcttc gagctcagcc
     4141 ggggcgtgga gttcccgacc ttcgcgatgc cgaccatcat cggcgagatc aagcggttct
     4201 tccgcgacac cagctggtcc gtgcgcgtgc cgcgccggct ccaggagctc cgcatcgacc
     4261 tggccaaggc ccgcgacgag ctcgcccaga gcctggaccg ctcccccacc gtcggtgaac
     4321 tcgccgggca cctcggcctg acgaaggacg aggtcgtcga gggcatggcc gcgagcaacg
     4381 cctactcggc gagctcgctg gacgcccagc cgcaggacga cgaggcggag ggcgccctct
     4441 cggcccgcat cggctacgag gaccacgacc tggagggcgt cgagtacgtc gccgcgctca
     4501 agccgatgat cgccgaactc ccgcaacggg accggaagat cctgtccctg cgcttcgtgg
     4561 cgaacatgac ccagtcggag atcggcgagg aactgggcat ctcccagatg cacgtctcgc
     4621 gcctgctggg ccgcaccctc gtccgcctgc gccggggact cctgagcgag gagtgaggcc
     4681 ggggcctcag cttttgcacg gtattcacac cgtttccgca ccgccgcgcg ccgcacgggt
     4741 ttcccgtgcg gcgcgcggcg tttgatgccg cctcagcagc tgcagggccg tgcccacccc
     4801 tgcacaaacc tggaccgggg atgcgcgccg agggtgttga cccgcctgct gcgggcgaat
     4861 agcgtcgcgg cggcctctgg gggaacggcg gtgcgactgg cgtgcgcctt ctgcgggaag
     4921 accaggaaaa ccgggaagac cggcaagacc ggcaaatcca ggacgacggt ggcggtagcg
     4981 gtagcggtgc cgatgtcgtc atcgtcggca gcggagtggt cggcgcggcg tgtgcggagg
     5041 cgctgacccg ccgcggggcc cgcgtgctcg tcctcgaccg gggcccgctc gcggccggca
     5101 ccaccgcctg cggtgagggc aacctcctcg tctcgaacaa ggcccccggc cccggactcg
     5161 ccctcgcaca ggcctcgctg agccgctggc cccgcctgct cgccgcgctg cgcgaagagc
     5221 tgggcccggg ccgtgcggag tgcgagtacg aggtgaaggg cggcctcgtc gtcgccaccg
     5281 gcgagccgga gggcgcggcc ctgtgcggct tcgcggcggc ccagcgcgcg gcgggcgtgg
     5341 acgcccgcga gctcgcgccg ggcgaggccg cggcgtacga gccgcacctc acgcccgccg
     5401 tgcgcgccgc ggtccactac ccgcaggacg cccagctgca gcccgtcctg gcggcgacgt
     5461 cgctgctggc ggcggtccgg gcgcgcggcg gccggatccg taccggcgtg gacgtgacgg
     5521 gcgtggagac cggccgggac gggcgggccg tgggcgtccg cacgtcgcag ggccgcattc
     5581 cgtgcggggc ggtggtcaac gcctgcggcc cctgggccgg ggagttcgcc gcggccgccg
     5641 gcgcgcccct gcccgtcgtg ccccgccgcg gcacggtcct cgtcacggca ccgctgccgc
     5701 acggcacggt gcggcacaag gtctacgacg ccgggtacgc ggaaaccgcc cgcagcgagg
     5761 acgccgcact gcaggtggcg gccgtggtcg aggcgaccca ggcgggcacg gtcctcatcg
     5821 gttccagccg gcagcgctgc ggcttcgacg ggacgctgcg cgccggggtg ctgggggcac
     5881 tggcacgcgc ggcggcgcag ctgttccccg tcctcggcgg cgtccccgtc atgcgcgcgt
     5941 acggcggctt ccgcccgtac acccccgacc acctccccgt cgtgggcgag gacccgcgcc
     6001 accccggcct gtggcacgcg acgggccacg agggcgcggg catcggcctg gccgccgcca
     6061 ccggcgaact gctcgccgag ctctgggcgg gcgagccgcc gcacctcgat ccggagccgt
     6121 tccgtgtcca gcgcttcgga accgcacgaa ccacacgaac cgcacgcttc ggaagggaga
     6181 acggatggca ctgacggtgt acgtcgacgg cgagcggcac cgcgccctgc ccggtcagac
     6241 ggtggcggcc ctgctcctgg cgacgggccg ccggtcctgg cgcaccaccc gcctcggcgg
     6301 ccgcccgcgc ggcgtcttct gcggcatcgg cgtctgttac gactgcctgg tcgtcgtcaa
     6361 cggcctcccc gacgtacggg cctgccggcg cgaactgcgc gacggggacc gggtggagac
     6421 ccagcgcggc gcgcggctgc ccgcggagga ggagtcccgc ccggcccctc cgacccctcc
     6481 ggctcctccc gcccctcgta cggaccgtga ggacgcacat cccggtcacc ccttgcacga
     6541 ctcacacgac tcatgcaact catgcgactc atgccaatca cacggcttac gcgacttacg
     6601 cgacgcggac ggggtcgcat gagcgcccag cctcccttag cctcctcctc cgcctccgcc
     6661 tccgccactg ccaccgcctc ccccctcgtg gtcgtcgtcg gcgcgggacc ggccggcgcg
     6721 cgggccgcgt tgagcgccgc ccggtgcgac gcgcgcgtcg tgctcgccga cagcgaggag
     6781 cgcgtcggcg gccggcacca ccggcagccg gccgtcgcgg gcggcggccc cggcgcctcc
     6841 gccgcgcacc cgctcgaaca ggccgtcgcc acccagcccc gcatcacgca cctggcccgc
     6901 gccaccgtct gggccctgga gccggggccg gcgcccggca ggcacctcgt ccacctgcag
     6961 cagggccccg ccgacgaccg cgggcgcccc gtgcgcacgc tcgcggccga cgcgctcgtc
     7021 ctgtgcaccg gcgccttcga ccgcgcgttg ccgttccccg gctgggagct gccgggcgtg
     7081 gtcacggcgg gcgcggcgca ggcgctcgcc gaggggcagc ggacggcgcc cggcggccgg
     7141 gccgtggtgt cggggaccgg gccgttcctg ctgccggtcg cgctgtccct gctcggggtg
     7201 ggggcacagg tcctgggcgt gtacgaggcg gggaacccgg cgcgctggct gcgcagcccc
     7261 gccgcggccc tgcgcgacgg cggccccggc aggctcgccg agctgggctc gtacgcggtg
     7321 gggctggccc gccggcgcgt cccgtaccgc acgcggcacg cggtcgtcgc cgcgcacggc
     7381 cgcgaccggg tcgaggccgt caccgtcgcc cgcctcgacg cgggctggca cccggtggcg
     7441 ggcagcgagc agcgcatcgc acccgtggac gccgtgtgcg tcggctacgg gttcctcccg
     7501 cagctggagc tcccgctggc cgcaggctgc gcggtccgcg gcgggcacgt ggtggtcgac
     7561 gggcgccagg cgacgaccgt cccgggcgtg tacgcggcgg gcgagctcac gggcgtcgcg
     7621 ggcgcccccg ccgcggcggc ggagggcgag ctggcggggc tcgcggcggt ggcggacctg
     7681 gcggagcgcc cggaggcggc ggaggccggg gcgcgcctcg taccgccgtc gcccgcccgt
     7741 ctcgcggccg ccgcctcgcg ggtgcggtcc gggcggcggt tcgcgcgggc gctcgcccgg
     7801 gcgcatcccg tcccgggcgg ctggcgcggc tggctgcgcg aggacacgct cgtgtgccgg
     7861 tgcgaggagg tgtcgtacgg ggagctgcgg gacgccgtcg tggcgcgcgg cgcggacggg
     7921 atgcgggcgc tcaagctcac gtgccgcgcc gggctgggtg cctgccaggg ccgcatctgc
     7981 gggcggaaca cggccgagct cgccgcggcg ttcctgggct cccccgtcgc cgacccgtac
     8041 gccatggaca ggcggccgct ggcccatccg gtacggctcg gggatctcgc cgggccgcca
     8101 gccattgact agagctattc agccacccaa gatgtgcagt gttctattca gagccgccag
     8161 ggaggcaggg ccccatgtcc ggaccgcgac ccgtacgagc tgcgcgaggc agccggctga
     8221 gcacgctggg gtggcagcag gaagccgctc tgcgcatgct gcagaacaac ctcgaccccg
     8281 aggtcgccga gcaccccgac aagctcgtcg tctacggcgg cacgggcaag gccgcccgcg
     8341 actggcgctc gttcgacgcc atggtccgca cgctgcagac cctcaagcag gacgagacca
     8401 tgctcgtcca gtccggccgc ccggtcggcg tcatgcagac ccacgagtgg gcgccgcgcg
     8461 tcctcctcgc caactccaac ctcgtcggcg actgggccaa ctgggaggag ttccgccgcc
     8521 tggagcacct cggcctcacc atgtacggcc agatgaccgc cggctcgtgg atctacatcg
     8581 gcacacaggg catcctgcag ggcacgtacg agaccttcgc cgccgtcgcc gccaagaagt
     8641 tcgacggaac gctggccggc acgatcaccc tgacggccgg gctcggcggc atgggcggcg
     8701 cccagccgct cgccgtcacc atgaacgacg gcgtcgccat ctgcatcgac tgcgacccgc
     8761 gcgcgatcga ccgccgcatc gagcaccgct acctggacgt gaaggccgac tcgctcgacc
     8821 acgccctgca gctggccgtc gaggcgcgcg acgcccgccg cccgctgtcc atcggcgtcc
     8881 tcggcaacgc cgcggagctc gtcccgcagc tgctcgcgat gaacgccccg atcgacatcg
     8941 tgaccgacca gaccagtgcc cacgacccgc tggcctacct gccggtcggc gtctccttcg
     9001 acgacatggc cacctacgcg gccgagaagc ccgccgactt cacgacgcgg gcgcgcgagt
     9061 ccatggcccg gcacgtcgag gccatggtcg gcttccagga cgccggcgcc gaggtcttcg
     9121 actacggcaa ctccatccgc ggcgaggccc agctcgcggg ctacacccgc gccttcgact
     9181 tccccggctt cgtccccgcc tacatccgcc ccctcttctg cgagggcaag ggccccttcc
     9241 gctgggcggc cctctccggc gacccggccg acatccacaa gaccgacaag gcgatactcg
     9301 aactcttccc cgagaacgag tccctcgccc gctggatcaa gatggccggc gagcgggtgc
     9361 acttccaggg cctgccggcg cgcatctgct ggctgggcta cggcgagcgc gacaaggccg
     9421 gcgagcgctt caacgacatg gtcgccgacg gcacgctcgc cgcgccgctg gccatcggcc
     9481 gcgaccacct cgactgcggc tcggtggcct ccccgtaccg cgagaccgag gccatgctcg
     9541 acggctccga cgcgatcgcc gactggccgc tgctcaacgc gatggtcaac gtcgcctcgg
     9601 gcgcctcgtg ggtctccatc caccacggcg gcggcgtcgg catgggccgc tccatccacg
     9661 cgggccaggt cacggtcgcc gacggcacgc cgctggccgg cgagaagatc cgccgcgtcc
     9721 tgacgaacga ccccggcatg ggcgtcatcc gtcacgtcga cgccgggtac gacatcgcgg
     9781 agtcggtcgc ggaggaccgc ggggtgcgcg tccccatgcg ggagggcgaa tgagcagccc
     9841 ggctgcgggc gaggtgaagg caggggcttc gttccacgag atgtggcgcg acctcgcgtc
     9901 catcggccgt gacaaggaca ccgccggcta tcaccgcttc gcctggagcg gcgccgacgc
     9961 cgactgccgc gcctggttcc gcgcccaggc ggagtcccgc gggctcgcct acgagctcga
    10021 ccgcaacggc aaccagtggg catggctcgg cgacccggcc gccggggacg ccgtcgtcac
    10081 cggctcccac ctggactccg tgccgaacgg cggcgccttc gacggccccc tcggcgtggt
    10141 ctcctccttc gccgcgctgg acgagctccg cgcccgcggg gcgcagccgt cccgccccct
    10201 cgccgtcgtc aacttcggcg acgaggaggg cgcccgcttc ggcctggcct gcgtgggctc
    10261 ccggctgacc gccggtcagc tgtccctcga caaggcgcac gcgctccggg acgccgaggg
    10321 cgtctccctg cccctggcca tggagcgcgc cggctacgac ccggaggcca tcggcccgga
    10381 ccccgagcgc ctggcccgga tcggcgcctt cgtcgagctc cacgtcgagc agggccgcgc
    10441 cctggacctg tcggaccgcg ccgtcgggat cgcctccgcc atctggccgc acggccgctg
    10501 gcggttcgac ttccacggcg aggccaacca cgccggcacc acccgcatcg aggaccgccg
    10561 cgacccgatg ctcacctacg ccaacaccgt cctggccgcc cgcaagaagg cccggctggc
    10621 cggcgccctc gcgaccttcg ggaaggtcgg cgtcgagccg aacggcgtca acgccatccc
    10681 ctcgctcgtg cgcggctggc tggattcgcg ggccgccgac caggagaccc tcgacctcgt
    10741 ggtcgcggag atcgagaagg cggccgtgga gcgcggcgag cgcgacggcg tcgacgtgcg
    10801 ggtcacccgg gagtccttca cgcccgtcgt ggaattcgag cacgccctgc gcgacgagct
    10861 gggccgcatc ctgggcgggg acgtccccgt cctcggtacg ggtgcgggac acgacgccgg
    10921 aatcctctcc ggagccgtcc ccaccgccat gctgttcgta cgcaacccca caggcgtctc
    10981 gcactcaccc gccgaaacgg cttccgagga cgactgcctg gccggggtga ccgcactcgc
    11041 cgacgtactg gagggcctgg cgtgtcgctg acggcacaga cctactgggc ggagcacgcc
    11101 cttctcgaca ccggcgtcga gccgggcgtg gtcatcgaga ccgggacgga cggccgcatc
    11161 aaggccgtcc gccggggcgc cgcggcaccg ccccagggcg cggtgaccct gcggggcctg
    11221 accctgcccg gtctcgcgaa cgcgcacagc cacgccttcc accgggccct gcgcggcgcg
    11281 acgcaggcgg gcgaggggac cttctggacc tggcgcgacg tcatgtaccg cgtcgccgac
    11341 aacctcaccc ccgacagcta cttcgcgctc gcccgtgcgg cctacgccga gatggcgctc
    11401 gccggcatca cctccgtcgg cgagttccac tacgtgcacc acctcgccgg gggcgcccgc
    11461 tacgacaacc ccaacgccat gggcgaggcc ctgatcgcgg ccgccgccga ggcgggcatc
    11521 cgcatcacgc tcctcgacgc ctgctacctc tcctccggct tcggcgccga gcccaacaag
    11581 caccagcggc gcttcagcga cggcaccgcc gagcgctggg ccgagcgcgt ctccgccctc
    11641 aagggcgacg acaacacccg catcggcgcg gcgatccact cggtgcgggc cgtgcccgcc
    11701 gagcagctgg cgaccgtggc cgcgtgggcg caggagcgcg acgccccgct gcacctgcac
    11761 ctctccgagc agaccgccga gaacgacgcg tgcgtggagg cccacggctt cacgcccacc
    11821 gccctcctct cgcaccacgg cgtgctcggc ccgcgcacga ccgccgtcca cgccacgcac
    11881 ctcacccccg gcgacatccg cctcctcggc cactcgggca ccggcgtgtg catgtgcccg
    11941 accaccgagc gggacctggc cgacgggatc ggaccggccc gggcgctgca ggaggcgggc
    12001 tccccgctct ccctcggcag cgacagccac gccgtcatcg acctgctcga agaggcccgc
    12061 gccatggagc tggacgagcg gctgcacagc cgcacccgcg gccactggac cgcggtccag
    12121 ctgctgcgcg cggccacggc cgacggccac gcggccctcg gctgggacgg ggcgggccgc
    12181 atcgagcggg gcgcgctcgc ggacttcacg gccgtcgcgc tcgactccgt gcgcaccgcg
    12241 ggccagccgt acgccctcgc cgccgagacg gccgtcttcg cggcgagcgc cgcggacgtc
    12301 cgggacaccg tggtgggcgg ccggcacatc gtgcgcgagg gggcgcacca gctcgtggcc
    12361 cacgtgccgg cggcgctggc ggagtccatc gcggccgtac ggggctgaac caccgaaccg
    12421 accaaaggag tgccgcacgc ccatggcgac gacggtcatc accaacatca gcagtctcgt
    12481 cacgaacgac ccctccctcg gcgaaggccc cctcggcacg atccgggacg cggcggtcgt
    12541 catcgacggc gaccgcgtcg cctgggtcgg cacgtccagc aaagcaccgg ccactgacaa
    12601 ccgggtcgac gccgagggcc gggccgccct cccgggcttc gtcgactccc actcccacct
    12661 ggtcttcgcg ggcgaccgca cggccgagtt caacgcccgc atgtccggcc ggagctacag
    12721 cgccggcggc atccgcacca ccgtcgccgc cacgcgcgcc gcgaccgacg aggcgctgga
    12781 cgccaacgtc cggcgctacg tgcacgaggc cctgcgccag ggcaccacgg tcctggagac
    12841 caagtccggc tacggcctca ccgtcgagga cgaggcccgc gccctgcgca tcgccgcggc
    12901 gcacaccgac gaggtcacct acctcggcgc ccacatcgtc tcccccgact acgccgacga
    12961 cccggccgcg tacgtggacc tcgtgaccgg gccgatgctc gacgcctgcg cgccgcacgc
    13021 ccgctgggtc gacgtgttct gcgagcaggg cgcgttcgac ggcgaccagg cccggacgat
    13081 cctcacggcc ggcgccgccc gcgggctgac gc
//
