LOCUS       NZ_LNBE01000003        23955 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces roseifaciens strain MBT76 scaffold_3, whole genome
            shotgun sequence.
ACCESSION   NZ_LNBE01000003
VERSION     NZ_LNBE01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseifaciens
  ORGANISM  Streptomyces roseifaciens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 2630732)
  AUTHORS   Wu,C., Zhu,H., van Wezel,G.P. and Choi,Y.H.
  TITLE     Metabolomics-guided analysis of isocoumarin production by
            Streptomyces species MBT76 and biotransformation of flavonoids and
            phenylpropanoids
  JOURNAL   Metabolomics 12, 90 (2016)
   PUBMED   27073352
REFERENCE   2  (bases 1 to 2630732)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     The complementarity of genome-mining and NMR metabolic-profiling
            facilitates lead-finding
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 2630732)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2015) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.06
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001445655.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 03:28:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,528
            CDSs (total)                      :: 7,450
            Genes (coding)                    :: 7,245
            CDSs (with protein)               :: 7,245
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 205
            CDSs (without protein)            :: 205
            Pseudo Genes (ambiguous residues) :: 0 of 205
            Pseudo Genes (frameshifted)       :: 77 of 205
            Pseudo Genes (incomplete)         :: 168 of 205
            Pseudo Genes (internal stop)      :: 20 of 205
            Pseudo Genes (multiple problems)  :: 56 of 205
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:37:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1428413
            Orig. end                         :: 1452368
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LNBE01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23955
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="11"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23955
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23955
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13955]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13955
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(654..669)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.45"
                     /tool="antismash"
     gene            complement(850..1305)
                     /locus_tag="AS857_RS12040"
     CDS             complement(850..1305)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AS857_RS12040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_063804232.1"
                     /transl_table=11
                     /translation="MENRLQILLSEEGTEAEHVEKLTGYLRRELLQLDVDDVTSLPADA
                     EVPPGARAVDVTQVGALLVTLGTSATALREVVGVVREWWGRCRDSRPSMRLALGDDVLE
                     VSEATPEQVTEAFDLFVRRHSPGAAPSGAASPAEVPTGEVPKGEVPP"
     gene            complement(1491..2396)
                     /locus_tag="AS857_RS12045"
     CDS             complement(1491..2396)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018092642.1"
                     /locus_tag="AS857_RS12045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_058044092.1"
                     /transl_table=11
                     /translation="MDLRLLASFLAVVEEGHFARAAARLFLSPPAVTQHVRRLESDLGT
                     RLLHRNPVSPTPAGERLAGHARTLLAAANAALDDVAEAAQAAPAAERPLRVGIMGHGSA
                     ELTPASINAFRRARPHVPVELRQLDFTEHVSALVEDRVDVAFVRPTPADERITADAMTT
                     EQRIVAVPESSPLADARDTGALLADIADLPFFTVPGHTPRTFTDYLYFDCAARRRSPHV
                     ALTPQEVLTGVVTGRAAGSGLKSFARYYAWPGAVFVPVLDAPHESSYLAVRARDRNPEV
                     QIFRALALALAREMGPRISA"
     misc_feature    complement(2427..2442)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.82"
                     /tool="antismash"
     misc_feature    complement(2430..2443)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.94"
                     /tool="antismash"
     misc_feature    complement(2435..2448)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.08"
                     /tool="antismash"
     misc_feature    complement(2440..2454)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.3"
                     /tool="antismash"
     misc_feature    complement(2441..2450)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.08"
                     /tool="antismash"
     misc_feature    2539..2551
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            2757..3992
                     /locus_tag="AS857_RS12050"
     CDS             2757..3992
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003980559.1"
                     /locus_tag="AS857_RS12050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_245699790.1"
                     /transl_table=11
                     /translation="MRTGWMMTASGWSANQFSALLGAYRSELGLSESAVTGLFALYVVG
                     LIPGLLIGGPLADRRGRRPVALTALAVNLLSTCLLMAGSAATAWLLPGRFLTGISAGAL
                     LAAGSAWVKELSCPPYAPEGVPGAAARRPGLFVSAGFASGGLVAALIAQWLPYPMATAY
                     VPHVVLAALAWAIAYRAPETRRPAARDGRAAAAGHGADAAAPDGAVDWSRFRRAVLPLA
                     PWVFAAPAIGFATLPGLVDDGLTGWRTVYAGIATAVVPGCGLLVQPLARRLAVRNRFAT
                     ASAGLGAITVGLALAVPAAAAAQPALALVAAAVLGAGYGFALSFGLTEAAAAAPPARLA
                     MVTSLFWTAAYLGMLVPYALALLSRWWSMPVLLAAGAVLAAVTCGVFAAVGGRRNAPAA
                     LHRTAEPDRPRA"
     gene            complement(4199..5320)
                     /locus_tag="AS857_RS12055"
     CDS             complement(4199..5320)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009712170.1"
                     /locus_tag="AS857_RS12055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="barstar family protein"
                     /protein_id="WP_058043104.1"
                     /transl_table=11
                     /translation="MIPTVYEDDDANGRGWARYTLTDTEHGHVWGTCDEVEGLFGEFQR
                     GTYELFGWVPEGPEVRDWVGNRVWLVPEDEELDAWLLEDVERLDVESPGRRPGANGLVL
                     TGQDDYEGPPEGYRGTVRVHDGHRWLGSCREFTRVLTPEQAAPLLVLRGLAAGEELRRV
                     LATGTRRALDLDETALEIRDDRGEPLTDRLLWPTVRDWRPSALGTDLIDLELDCSSLYP
                     PIPEHARPIRDRWLAGPPNSPGAWVGLDSRQRLAWLDIVRERGCRLKRQDRPAHHAYEL
                     DGRHITDDPGLYLALGEAVNGPGGYFGGCLSALDDCLRGTFGYTAPATLLWRDAATARE
                     HLSHALTPDGRPYDLFAEVLDSLAEGGMHVTLA"
     gene            complement(5699..6829)
                     /locus_tag="AS857_RS12060"
     CDS             complement(5699..6829)
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0004722 - protein serine/threonine
                     phosphatase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016579274.1"
                     /locus_tag="AS857_RS12060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PP2C family protein-serine/threonine phosphatase"
                     /protein_id="WP_058043105.1"
                     /transl_table=11
                     /translation="MPLPRSVPGFGRWWHTGRSLVAVPLGLIALVMFVDLLTPPDIHLG
                     PLLVAAPAISAAIGGPVLTAVIGALAVTAQVVIGIFHGGLETPNHQAQIAALLLISVFL
                     VLFRRAREQREQELSQARWVAEVAQRVLLRPVPTRLGPLRIASMYVAAEAEARIGGDLY
                     AAARTVHGTRVMIGDVRGKGLPTIGDAASLLGAFRAAAHRNPPLPRLVAHLQNATYWDM
                     AEPADDRTTGEGFITAAVLDIPDDQPVLRLINCGHPPPLVLSDGKVTTLTVADPALPLG
                     LAGGLTEDDYESESFPYRAGDVLLLYTDGVIETRDAGGGFYPLADRVAAWQETDPDRLV
                     QRLHRDLLAYAGGAMADDVAVMALERLPREDPQDSA"
     gene            complement(6921..8426)
                     /locus_tag="AS857_RS12065"
     CDS             complement(6921..8426)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031823.1"
                     /locus_tag="AS857_RS12065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytosine permease"
                     /protein_id="WP_079110263.1"
                     /transl_table=11
                     /translation="MTSPEQPSSRSPLAPERRTIEVVPDAERHGAPHSQFTLWFGASMQ
                     ITAVVDGALAVVFGADALWAIPALLVGNVLGGVVMALHSAQGPRLGIPQMISSRAQFGV
                     LGAVVPLVMVILMYLGFAATGSVLAGQAVRRILHLPGTTPGILVFGVLTAVVALAGYRL
                     IHLAGRIATVVGSIGLGYLLVAVFTRYDVGAHVGRQPFDAATFLLAVSLGAGWQLTFGP
                     YVADYSRYLPRTTSARAAFWSTFSGSVLGAQWAMSLGALIAAVAGESFLSDQVGFVGEL
                     AGPAAVGFLVHLVVLVGKLTVNCLNAYGGFMSILTTVTAFDGRSRITPAARALYITAFT
                     AAATVVAVAASADFLDNFKNFVLLLLMVFTPWSAINLTDYYLVSRERVDIPALYDPDGR
                     YGRWNVPALSSYALGVLAQIPFLAQKLYTGPLTERLGGADVSWIVGLVFTAAVYLPWAR
                     HTADPPAETVHPAADEPEDEPEDKPEDDSDSDSNRRNPATAEN"
     tRNA            8593..8665
                     /anticodon=(pos:1437039..1437041,aa:Ala,seq:ggc)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="AS857_RS12070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /product="tRNA-Ala"
     gene            8593..8665
                     /locus_tag="AS857_RS12070"
     misc_feature    complement(8795..8807)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     misc_feature    8881..8895
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.56"
                     /tool="antismash"
     misc_feature    8904..8918
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.65"
                     /tool="antismash"
     gene            8928..10028
                     /locus_tag="AS857_RS12075"
     CDS             8928..10028
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007492352.1"
                     /locus_tag="AS857_RS12075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ionic transporter y4hA"
                     /protein_id="WP_058043106.1"
                     /transl_table=11
                     /translation="MNSRLHFLAARWPALVPALAAVVLALTWGRSLSAGTVALVSCCLA
                     GAVLAAVHHAEVIAHRVGEPFGSLVLAVAVTVIEVALIVTLMADGGDKSASLARDTVFA
                     AVMITCNGIVGLSLLVCALRRRVAVFNAEGTGAAFATVATLAGLSLALPTFTTSTPGPQ
                     FSPAQLVFAAVASLLLYGLFVATQTVRHRDYFLPVTAQGEVIDTDDHAEPPTARTALTS
                     LGLLAVALVSVVGLAKGVSPTIESGVAAAGLPASVVGVVIALLVLLPETIAALRAARRD
                     RVQTSLNLGLGSAMASIGLTIPAVAVASIWLDGPLLLGLGATHMVLLALTVAVGTLTVI
                     PGRATPLQGGVHLSLLAAYVVLAVSP"
     gene            complement(10001..11074)
                     /locus_tag="AS857_RS12080"
     CDS             complement(10001..11074)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="AS857_RS12080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_107105560.1"
                     /sec_met_domain="T1TS (E-value: 4.8e-56, bitscore: 188.0,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRLNLFFCPLPLRISPDAERARAHTWEWCQETGMAASPEAAALW
                     DAYRLDLWGSCVWWYCTGDLLDLVTDWGTWGVMLDDVLEVHDPELIRDTVDEMKQIFDT
                     NDPDAPGACAGPFTVALSDLWRRTQAHGMSVRWQRRTANRFSRFLDSYLRDAVYRRDGV
                     WPTVEHYLDDRIWSTAALANMCFNDLEHRCELSDDIVMHPVLHAMQRATGDHIALVNDI
                     TGVHREASWNDHINVVPLIQRQYRCTQEEAIARAVTMADQRMHSFLALERALPDLCAHL
                     DVTPEERECIGHLTRGLRSWLSGNIEYHLISPRYEERPRPASRHTAAWMTDAHRVPARI
                     PAPVPARVPQGLTASTT"
     gene            complement(11102..12136)
                     /locus_tag="AS857_RS12085"
     CDS             complement(11102..12136)
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039286.3"
                     /locus_tag="AS857_RS12085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rieske 2Fe-2S domain-containing protein"
                     /protein_id="WP_079110264.1"
                     /transl_table=11
                     /translation="MKIPSAFRFHLARSTGETPLVTGNRATPRLPYPDGWYAVAFRDEL
                     PAGRVLTRHLTGEDVVLYRTRSGLVRAVRPFCPHLGAHLGHGGRVDGENIVCPFHHFAF
                     SPSGDCVRTGCGSPPPKARLRLLEVRETDGIVLVWHHSRGHPAAWEVRSSKPAEFCPAG
                     HVSYTLADHPQDVMENSVDTAHGPPIHGMAIDIKGLRFSGTVMEADLATTPAKGSSGGF
                     LVSHQVHYSLRLQGLGWLFVDARIPRLRTHVHFWVLPVPVDPLRVEIRLAVNVEECLGL
                     TAPGRTTRLIGKVLAPLIGLDMAKDFPVWQNKAYVAHPKLTKGDGPIMEYRRWAGQFYS
                     EPSP"
     gene            12375..13955
                     /locus_tag="AS857_RS12090"
     CDS             12375..13955
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024640.4"
                     /locus_tag="AS857_RS12090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_160330217.1"
                     /sec_met_domain="T2TS (E-value: 3.5e-69, bitscore: 230.8,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTTAGGASGPDRPTARRIREAVGRLMAGLGDTGTCSDSYNTAF
                     VSRVRDPDGSPRYPRALQWLQERQHPDGSWGGRIALPADRLTSTLAAVRALVDYAETTP
                     PGPYDWVAGALKRGTGHLKSLAREWRAGPHEPIGFEFVVPELTRRLRAHGVDLPPQAWP
                     DIHALRRDKIARMAAASAGSLSPSLSPSLRYCMEVAPDEAFAGVALTLQSPGGSVGCSP
                     AATAALWQSTGDARALAYLDHLAHRSRDGGAPEVHPVEAFETGWSLYHLGRAGLLPPGA
                     AQHLDALAGELDRRGWVGFSREFPAPEADTTAMTINLLSHLGVEAASRLGLLLRYEADD
                     HFFHYPGERGASVSVNARLLEAFNHAPGMYGPQRRKLIRFLLESRAADGSWLDKWHMSP
                     YYATAHVCFALGRSASAEGPLTRTHEWLLDTQHPNGSWGAGGGQPEETAYAILALDALA
                     GSGLPLPARTSHLAHRYLVPHLDAGPDAFAELWLGKSLYTPTAVVQSAVIAAAHLTRLR
                     LTTPRARGD"
     gene            complement(13887..14753)
                     /locus_tag="AS857_RS12095"
     CDS             complement(13887..14753)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013757.4"
                     /locus_tag="AS857_RS12095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="IclR family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_058043109.1"
                     /transl_table=11
                     /translation="MTQTRWDPQTPAEVRTIPEATFERGAVGRALRVLEMVCQDARPRG
                     LSEIARETGVPKATTYRILTALCAHGMIGRWDDKYVAGERLAELASKRVTRRNQLSVLR
                     ATAMPFLLDLYDSLGGFVGLGVHEGRQVRYVERIHGRRLQPLLSRTGETVPASSTAIGK
                     LLLAFEHDAQAADWPPHEELEDELAVIRHTGIAVERQEYASGMLTVAAPVLGPDRLVLA
                     GVVIGDTTGRTALKRAVGELRRTAFALTIALRRLNTDSLPSPAESVAARPRRGEAEPRE
                     MGGGDDG"
     gene            complement(14773..16116)
                     /locus_tag="AS857_RS12100"
     CDS             complement(14773..16116)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018560295.1"
                     /locus_tag="AS857_RS12100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_058043110.1"
                     /sec_met_domain="p450 (E-value: 1.2e-75, bitscore: 252.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTAASIPLAPNAVPLLGHVLPLVRDPLAFLSSLPARGELVRIRM
                     GPRSVVMVCDPVLTRQVLLNDHVFDKGGPMYERVREVVSDGLISCPHSRHRRQRRLCQP
                     SFHPERFPHYSAVFVAAAEGVARSWHDGQVVDVTTEMTKLATRVAVETMFTAALPPEAA
                     QQTVGDINTVVNGAFRRMIRPALLNRLPSPGNRRYLRARERLQHTASSVAGRRSADSTD
                     HRDLLSSLQSATDPDSLADGARALTDAELADQVLTFFLAGAETTSNAMAWALYLLAEHP
                     EVEERLHAESARVLGGASPAFADLPALQEAGHVVHEALRLYPPAWLLTRTVVEDTELGG
                     VTLPAETLIAFSPYLIHRRPDLYEDPDRFDPDRWRGPQPDRTVYLPFGAGARKCIGARF
                     AVAEATLALTAINARWRLVPLSGRPVRPSAKVTLGPRGLRMRVIARRA"
     misc_feature    complement(16345..16360)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 24.01"
                     /tool="antismash"
     gene            16442..17536
                     /locus_tag="AS857_RS12105"
     CDS             16442..17536
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011028391.1"
                     /locus_tag="AS857_RS12105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="chitinase"
                     /protein_id="WP_058043111.1"
                     /transl_table=11
                     /translation="MIGRMARLLAGAAGVCLGTVLAGPAPLQTESQVAYGTAAAVSGPG
                     ADTCPVQSRPSGKVLQGYWENWDGAANGVHPPFGWVPITDARIGEHGYNVINAAFPVIR
                     SDGTVLWEDGMDATVKVATPTEMCRAKAAGATILMSIGGAAAGIDLGSGTVADRFVETV
                     VPILKTYNFDGIDIDIETGLTGSGNINTLSASQANLIRIIDGVLARMPSNFGLTMAPET
                     AYVTGGSVTYGSIWGAYLPIVKKYADNGRLWWLNMQYYNGNLYGCSGDSYSAGTVKGFT
                     VQTDCLNKGLVVQGTTIRVPYDKQVPGLPAQPGAGGGYMSPGLVAQAWNTYGNGLKGLM
                     TWSVNWDGSKGWTFGNNVRALQGR"
     misc_feature    17720..17733
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.56"
                     /tool="antismash"
     gene            17753..18424
                     /locus_tag="AS857_RS12110"
     CDS             17753..18424
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019887149.1"
                     /locus_tag="AS857_RS12110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4097 family beta strand repeat-containing
                     protein"
                     /protein_id="WP_058043112.1"
                     /transl_table=11
                     /translation="MQKFHTPAAVAAVLDIPAGRIRFIAADRTDTTVEVLPADASKGRD
                     VKAAERTTVEYGDGVLRIADPAAETRTLGNPGSVEVTIQLPAGSRIEAKTATAEIRGVG
                     RLGDVTLNSAHGSIKLDETANAHLTLAAGDITVGRLGGPAQISTQKGNLHITEAMHGTV
                     TLRTEAGDITIGAARGVSASLDAGTSYGRIHNALKNTDSTDTQLDIHATTAYGNITARS
                     L"
     gene            18592..20868
                     /locus_tag="AS857_RS12115"
     CDS             18592..20868
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891812.1"
                     /locus_tag="AS857_RS12115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DPP IV N-terminal domain-containing protein"
                     /protein_id="WP_058043113.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.1e-38, bitscore:
                     129.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTQDYQAAEQLLRRPARPGELVIGDKVRPQWIDGGARFWYAVS
                     NGVGRRFVLVDPAAGTREPAFDHALLADALAAASGQQVDPEALPFIGIELAGNAVEFHA
                     FGEYWRCRLDGYACERAEFTPPGSPLDVLSPDKKVAVSQRGHDLWARSLSDGREWALTT
                     DGEPDHRYGSGPDCTSNGTLLRKIGLPHLPPAVAWSPDSTKVLAHRTDERGVRQTHLVE
                     ARPADGGAPLLHTQRYAYPGDEQVPQAELVVLDVQAGTMVRAQAAPLLMPQLSPITTKW
                     AWWAQDGSAVYYLSRPRDLRTLTLHRLDPATGEVTTVLSETGATRVEPNQWMYEAPIVR
                     VLADEVLWYSQRDGWGHLYRYDLRTGELLGQVTSGEWAVREILRVDEAERVVYFTAVGL
                     VDEDPYRRTVCRVGLDGSGFAKVTDDELDHVVTMPDDQEYFIDSASTVDTPPVTTVRDR
                     TGRVLVELERADISKLTATGWTPPERFRVKAADGVTDIYGVLYRPRGFDPARRYPVVDN
                     LYPGPQVNRVAPCFDPGGMGLDAEPLAALGFVVVALDGRGTPGRSKSFHDASYGRLADA
                     GCLADHVAALRQLAGTRPWMDLDRVGAFGHSGGGFAAARAMLDFPEVYKAGVALSGSHD
                     ARCFNLGFVETYDGAANPEAWARSSNVDLADRLAGKLLLVHGEMDDQVHPDHTLRLADR
                     LIAADKDFELLIVPGAEHTFIDCLAYVRKRCWDFLVRELMGTQPPAHRPAPIAIGPELL
                     GELFA"
     gene            21065..21976
                     /locus_tag="AS857_RS12120"
     CDS             21065..21976
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AS857_RS12120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_144440787.1"
                     /transl_table=11
                     /translation="MLARTLALAALLAVPAGVCTAAPAPPAPWVPPAPLVPPAPLMPLA
                     PARAPAPAPEAAVTQRCAPAAVLKGKGTGKGGQSAKAGVCVTLDNAFMTVTAPAECGRG
                     TCDTSGTWRMRRGGREVASGELARRAGYPGPGTYEITTTLRVRSVPAGVDFRAERTVRV
                     TLSWPRPKATHRIDVSPRTVRAGRTTTVTYTVSRLGPDGDSNARLGLIGVEKTGVQLTS
                     SDPRCSNPLSGAYPSEARHPYVLNCDFVELQPGRPGVVKVRVRMGEACSPVVSKMGYWL
                     PKGQETYTGNMLVGPTVGCVKG"
     gene            21973..22419
                     /locus_tag="AS857_RS12125"
     CDS             21973..22419
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713073.1"
                     /locus_tag="AS857_RS12125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_058043115.1"
                     /transl_table=11
                     /translation="MSAGGEGVLARAHVATRLPARDLDRARRFYSEQLGLEPVDERPGG
                     LLYRCGGVDFAVFLSTGASSGEFTQMAWEVDDIEEAVAELKRRGVVFEDVELPGPPGAP
                     AAGRTEDGIVDIDGNYPSKGARGERGAWFRDSEGNMLGIGQPVV"
     misc_feature    complement(23121..23130)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
     misc_feature    23253..23265
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
ORIGIN
        1 cggcgatggc cccgcggcgg gtgtagatgt cggggctgcg catcgcggcc tgtacgtcgt
       61 ccggaacggg ggagggggcg atccgccgcc gttggctgcg cgccaggtac aggtctccct
      121 gcatgtcgac gctgcggctg ggggtctggt tcgggttctc ctgccgtacg cggtcgaaga
      181 cgtactcgta cagctcgtcg agggagatcc ggccgtcctc gtccaggtcg gcctctccgg
      241 tggcgaggcc ggagacgagc gcgctggtga acaccgaggg ccgcgggccg gccgtctgcg
      301 tgagctcggc gccttcgaag gcgtactcca tggagttgga ggcggtgatg acggcccagc
      361 cgcgcccgcc gccgagcttc tcgcccgcga aggactccag gacgttgacg tcgccggcgg
      421 cgcgggcgac cgcgccctgg gggaaggcgc cgccgtagca gcagtccagg aagagggcga
      481 tgctgcgggc gcgggtgcag gacatgcaga ggcgtacgaa gtcggccggc acggcggtgg
      541 aggccaggcg ccggggcagc gtgttgctgg ccgcgaagta cagttcgccg gactcgctct
      601 tgagcccgtg gcaggagaag tggaccacga gggtgtcgcc cggccgccgg tcggcgaaga
      661 agtcgtcgag tcgcatggag atggcgtgcg aaggctcgtt ccgcacgatc tggacgtcga
      721 atccgccgat ccgcggatcg ccaaggacgt ccgccagcgc ctcggcgtcc tgggccgggg
      781 acatcagctg tcggagtcct tggtcctggt agctgtcgtt ggcgatgatc agcgcgtacc
      841 gggactccgt catggcggca cctcgccctt cggcacctcg cccgtcggca cctcagcggg
      901 cgacgctgct ccggacggcg ccgcaccggg ggagtggcgg cggacgaaga ggtcgaaggc
      961 ctcggtgacc tgctccggtg tcgcctcgga gacctccagg acgtcgtcgc cgagggccag
     1021 ccgcatcgaa ggccgggaat cccggcagcg gccccaccac tctctcacga cgccgacgac
     1081 ctcgcgcagc gccgtggcgg acgttcccaa ggtcaccagc agggctccca cctgggtgac
     1141 gtccacggcc cgcgcgcccg gcggcacctc tgcgtcggcc gggagggacg tcacgtcgtc
     1201 cacgtcgagc tggagcagct cccggcggag gtagccggtc agcttctcga cgtgctcggc
     1261 ttccgtcccc tcctcggaca ggaggatctg cagtcggttc tccaccgtat tcgccccttc
     1321 atccgcccct tcgcgcccag tcgcgcgtcc tcgcgctcac agctcacagg ggcgacgcgg
     1381 agtcggaccg cggtggctcc acgtgcctca cttccagtct gtgatccctc ctaccccgcc
     1441 gcaaccaggg tccgtgacca gggcacacac gacggacgcc gacgtgtccc tcacgcgctg
     1501 atccgtggcc ccatttcccg tgccagcgcc agggccagcg cgcggaagat ctgcacctcg
     1561 gggttgcggt cccgggcgcg aacggccagg tagctgctct cgtgaggggc gtcgagcacc
     1621 gggacgaaga ccgcgcccgg ccatgcgtag tagcgggcga acgacttcag cccggagccg
     1681 gccgcgcgcc cggtgaccac gccggtgagg acctcctgcg gcgtcagcgc cacgtgcggg
     1741 ctgcggcgcc gggccgcgca gtcgaagtac aggtagtcgg tgaaggtgcg gggcgtgtgg
     1801 ccggggaccg tgaagaacgg caggtcggcg atgtccgcga gcagggcgcc ggtgtcacgg
     1861 gcgtccgcca gcggcgacga ctccggtacc gccacgatgc gctgctcggt cgtcatggcg
     1921 tccgcggtga tccgctcgtc ggccggggtg ggccggacga aggcgacgtc cacgcggtcc
     1981 tcgacgagcg cggagacgtg ctcggtgaag tcgagctgcc gcagctcgac ggggacgtgg
     2041 gggcgggccc gccggaaggc gttgatcgag gcgggagtca gctccgccga gccgtggccc
     2101 atgatgccta cgcggagcgg tcgttcggcg gcgggcgcgg cctgagcggc ctcggccacg
     2161 tcgtcgagcg cggcgttcgc ggcggcgagc agcgtacggg cgtggccggc cagccgctcg
     2221 ccggcgggcg tgggggagac ggggttgcgg tggagcaggc gcgtgccgag gtcgctctcc
     2281 agccgccgga cgtgctgggt gacggcgggc ggggagagga agagccgtgc ggctgcccgc
     2341 gcgaagtgtc cttcctcgac caccgccagg aaggacgcca gcagacggag atccatgacg
     2401 gccacgatag acacctccgc cgcccggttc gcatgtgtat tcacaaatcg tgaatgcggg
     2461 cggcgggggc ggggcggagg cccgtaggac tggcggacgt gagtattcct gtcgagcaca
     2521 ccgcccctga cgccgctggt gccgttggca cccctgaggc aaccgctggt ccccccggta
     2581 cccctggcgc cgttggcatc cccggcgacc ccggtggttc cgttgccctc ccgcccaccg
     2641 accccgccgg gacgagcccg ccgccccggc accgcgcacg ggcgcgggcg ggtgggatgc
     2701 gcaccggccg gccgcgcacc ggccggccgc ggtccaggtg gatgcggtcc gggtggatgc
     2761 gaacgggctg gatgatgacg gcctccggct ggagcgccaa ccagttctcc gccctgctgg
     2821 gtgcctaccg ctccgagctc ggcctgtccg agtccgcggt caccggcctg ttcgcgctgt
     2881 acgtcgtcgg cctgatcccg ggcctgctga tcggcggacc gctggccgac cggcgcgggc
     2941 gccggccggt ggcgctgacc gccctcgccg tcaacctgct ctccacctgc ctcttgatgg
     3001 ccggttcggc cgccacggcg tggctgctgc ccggccgctt cctgaccggc atcagcgccg
     3061 gcgctctgct ggccgccgga agcgcctggg tcaaggagct gtcctgcccg ccctacgctc
     3121 cggaaggggt accgggggcg gcggcccggc gcccgggcct gttcgtctcg gcgggcttcg
     3181 cctcgggtgg cctggtggcc gcgctgatcg cccagtggct gccgtacccg atggcgacgg
     3241 cctacgttcc ccatgtcgtc ctggcggcac tcgcctgggc gatcgcgtac cgggcaccgg
     3301 agacccgccg gccggctgcg cgggacgggc gggctgcagc ggccggtcac ggggctgatg
     3361 ccgccgcccc tgatggcgcc gtcgactggt cccgcttccg ccgtgccgta ctgcccctgg
     3421 ccccctgggt ctttgccgcc ccggccatcg gcttcgccac cctgcccggg ctggtcgacg
     3481 acggactgac cggctggcgc accgtctacg cgggcatcgc caccgccgtc gtccccggct
     3541 gcggcctgct cgtccagccc ctggcccgcc gcctggccgt acggaaccgc ttcgccaccg
     3601 cgtcggccgg gctcggcgcg atcaccgtag ggctcgccct cgccgtccct gcggcggcgg
     3661 cagcgcagcc ggctctcgca ctcgtcgcgg cggccgtcct gggggccggt tacggtttcg
     3721 cgctgtcctt cgggctgacc gaggcggccg cggccgcacc gccggcgcgg ctggccatgg
     3781 tgacgtcgct gttctggacg gcggcctacc tcggcatgct cgttccgtac gccctcgccc
     3841 tgctctcccg ctggtggagc atgcccgtac tcctcgctgc gggagccgta ctggcggcag
     3901 tgacctgcgg tgtgttcgct gccgtcggtg ggcgccgcaa cgcacccgcc gcactccacc
     3961 gcacggcgga gccggaccgc cctcgcgcgt gatccctaac gtggcgagca ggcggaagag
     4021 tgatcgcatg gcagcgagcg tgagcgcaac acccgaagtt cccggtgtgt ctccgtcgtg
     4081 gtgtggtcca gccctggggc gaggtcgtgc cctctgtggg ggccgttggc gccggccgtg
     4141 acgtacgcct gccaccggcg ccgccgggcc ggctgctgaa aggcccggcg gcccgggatc
     4201 aggccagggt gacgtgcatc ccgccctcgg cgagggagtc gaggacttcg gcgaacaggt
     4261 cgtagggccg gccgtccggc gtgagggcgt gggacaggtg ctcgcgcgcg gtcgcggcgt
     4321 cgcgccagag cagggttgcc ggggccgtgt agccgaaggt gccgcgcagg cagtcgtcga
     4381 gggcgctcag gcaaccaccg aagtagccgc ccggcccgtt caccgcctcg cccagcgcga
     4441 ggtagaggcc cgggtcgtcg gtgatgtgcc ggccgtcgag ctcgtatgcg tggtgggccg
     4501 gccggtcctg acgcttgagt cggcagcctc gttcccggac gatgtccagc catgccaggc
     4561 gttgccggct gtcgaggccg acccaggcgc cggggctgtt cggcggcccg gcgagccacc
     4621 ggtcccggat cggccgggcg tgttccggga tgggcgggta gaggctgctg cagtccagct
     4681 ccaggtcgat cagatccgtt ccgagggcgg acggccgcca atcgcgaacg gtgggccaca
     4741 gcagccgatc agtgagtggc tcaccccggt cgtcccgtat ctccagggcg gtctcgtcca
     4801 gatccagtgc ccgccgagtc cctgtcgcca gtacccgccg cagttcttcc cccgctgcga
     4861 gcccgcgcag gacgagcagg ggcgccgctt gctcgggtgt caggacgcgg gtgaactccc
     4921 ggcaggaacc cagccaccgg tgcccgtcgt gcacccggac ggtgccccgg tagccctccg
     4981 gcgggccctc gtagtcgtcc tggccggtga gcaccagacc gttcgccccg gggcgccgac
     5041 cggggctctc cacgtcaagg cgctccacgt cttcgaggag ccaggcgtca agctcctcgt
     5101 cctccggcac cagccacacc ctgttgccga cccagtcgcg tacctcgggt ccctccggaa
     5161 cccagccgaa cagttcgtac gtcccgcgct ggaactcccc gaacaggccc tccacctcgt
     5221 cacaggtgcc ccagacgtgg ccgtgctcgg tatcggtcaa tgtgtagcgc gcccacccgc
     5281 ggccgttcgc atcgtcatcc tcatacacgg tcggaatcat gccctgacca gcggcggacg
     5341 atgaaggtgg gccttcggcg gcggtcgttg ccgcgccgcc gagcgccggg ctcgtcggca
     5401 ccaacggcac cggcaagtcc actctgctgc ggctgaagcc ggagacgcga gcgaggaacg
     5461 ggccctcgcg acccggggcg ctcgggctcg gcggcttcgg accggaccgc accgtgggcc
     5521 ggatgtccgg cggcgagacc gtcctccgcg ccgtcctgca cctgcatgaa ctgcgcccca
     5581 ggaccggggc gttgcgcgaa ggcaccctcc acgtgcacag cgctggcggg tggctgagcg
     5641 gtcggtcggc cggtcggccg gtcccgtgag gagcgagccc cttcctcaag ggtgggcgtc
     5701 acgcggagtc ctgcgggtct tcgcggggaa ggcgttcgag ggccatcacg gcgacgtcgt
     5761 cggccatcgc ccctcccgcg tacgcgagca ggtcgcggtg gaggcgctgg acgagccggt
     5821 ccgggtcggt ctcctgccag gcggcgaccc ggtcggccag cgggtagaag cctccgccgg
     5881 cgtcacgggt ctcgatgacg ccgtcggtgt agagcaggag gacgtcgccc gcgcggtagg
     5941 ggaacgactc ggactcgtag tcgtcctccg tcaggccgcc cgccaggccg agcggcagcg
     6001 cggggtcggc cacggtcagg gtggtgacct tgccgtcgct cagcacgagc gggggagggt
     6061 gtccgcagtt gatgagccgg agcaccggct ggtcgtccgg gatgtccagg accgcggcgg
     6121 tgatgaagcc ctcgccggtc gtccggtcgt cggcgggctc tgccatgtcc cagtacgtgg
     6181 cgttctgcag gtgcgcgacc agccgcggca gcggggggtt gcggtgggcc gccgcgcgga
     6241 aggcgccgag cagggaggcg gcgtccccga tcgtcgggag gcccttgccg cgcacgtcgc
     6301 cgatcatcac gcgcgtgccg tgcacggtcc gcgcggcggc gtacaggtcg ccaccgatcc
     6361 gggcctccgc ctcggccgcc acgtacatcg aggcgatccg caggggaccc agacgcgtcg
     6421 ggaccggccg cagcagtacg cgctgggcca cctccgccac ccagcgggcc tggctcagct
     6481 cctgctcgcg ctgctcgcgg gcgcggcgga agaggaccag gaagacggag atgagcagca
     6541 gtgcggcgat ctgggcctgg tggttcgggg tctccaggcc gccgtggaag atgccgatca
     6601 cgacctgggc cgtcacggcg agggccccga tgacggccgt gagcacgggt ccgccgatgg
     6661 ccgcgctgat cgccggcgcg gcgaccagaa gggggcccag gtggatgtca gggggtgtca
     6721 ggaggtcgac gaacatcacc agagcgatga gccccagcgg cacggcgacc agggaccggc
     6781 cggtgtgcca ccaccggccg aatccgggca cactgcgcgg aaggggcatg agtactgctt
     6841 accttctcgg tgacctccct gcacagctgc cacatcggtg gtgtcgcccc cggcggcgtt
     6901 agggcgtgtg tgcgaatggc tcagttctcg gcggtggccg ggttgcgacg gttgctgtcg
     6961 ctgtcgctgt cgtcctccgg cttgtcctcc ggctcgtcct ccggttcgtc cgccgccggg
     7021 tggacggtct cggcgggcgg gtcggcggtg tgccgggccc agggaaggta gacggccgcg
     7081 gtgaagacca gccccacgat ccaggagacg tccgcaccgc cgagccgttc cgtcagcgga
     7141 ccggtgtaga gcttctgggc caggaagggg atctgggcga ggacgccgag ggcgtagctg
     7201 ctcagtgcgg ggacgttcca gcgcccgtag cggccgtccg ggtcgtacag cgcggggatg
     7261 tcgacgcgtt cgcgcgaaac caggtagtag tcggtcaggt tgatggcgct ccagggcgtg
     7321 aacaccatga gcagcagcag gacgaaattc ttgaagttgt ccaggaagtc cgcgctcgcc
     7381 gcgaccgcga cgacggtggc cgccgccgtg aacgcggtga tgtacagcgc gcgggcggcc
     7441 ggcgtgatcc tggaccggcc gtcgaacgcg gtcaccgtcg tcaggatcga catgaaaccg
     7501 ccgtacgcat tgaggcagtt gacggtgagc ttgcccacca gcaccaccag gtggacgagg
     7561 aacccgacgg ccgccggccc cgccagctcg ccgacgaacc cgacctggtc ggacaggaag
     7621 gactcgccgg ccacggcggc gatcagggct cccaggctca tggcccactg cgccccgagg
     7681 acgctgcccg agaaggtcga ccagaaggcc gcccgggcgc tggtggtacg gggcaggtag
     7741 cgcgaatagt cggccacgta ggggccgaag gtgagttgcc agccggcgcc gagcgagacg
     7801 gcgagcagga acgtcgcggc gtcgaagggc tgccggccga cgtgcgcgcc gacgtcgtac
     7861 cgggtgaaca cggcgacgag gagatagccg agaccgatgc tgccgacgac ggtcgcgatc
     7921 cggcccgcga ggtggatgag gcggtatccg gccagggcga cgacggcggt cagcacgccg
     7981 aagacgagga ttccgggggt cgtgccgggc aggtgcagga tcctgcggac ggcctgcccg
     8041 gccagtacgg agccggtcgc cgcgaagccc aggtacatga ggatcaccat cacgagcggc
     8101 accactgcgc cgaggacgcc gaactgtgcg cggctcgaaa tcatctgggg gatcccgagc
     8161 cgcgggccct gggcggagtg cagagccatc accaccccgc cgaggacgtt gcccacgagc
     8221 agcgccggga tcgcccacag tgcgtcggcg ccgaagacga ccgccaaggc gccgtcgacg
     8281 acggcggtga tctgcatgct cgcgccgaac cagagggtga actggctgtg cggggcgccg
     8341 tgccgctcgg cgtccgggac cacctcgatc gtccggcgtt ccggggcgag gggggatcgg
     8401 gacgacggct gctcgggcga cgtcatgggt gccacactcc tggctcgact ccggctcgcg
     8461 cgatgttgcg cagaatctgg cacggggcga aaaccggagt caacgggtcg gtcgccgtcg
     8521 tgtaatattg ccgatgtcgc cggggaaacc gggcgaaaag cggaacagat gaacaactga
     8581 acagctgaac aaggggctat agctcagttg gtagagcgcc tgcatggcat gcaggaggtc
     8641 aggagttcaa ttctccttag ctccacagtg aacgagatgg aggccacccg ggtcgggtgg
     8701 cctccatctc gtcgtgcgct ccccgatgga gggagtttgc gcacccgtcc gggtgacggg
     8761 cgtttctcgg atcatcggac ggcgaagatc cttcatgaca gcggcacgct gcccttgccc
     8821 agtcctacca gccgcggact gggcaagggc gaggacggcc ggccgaggcg gcgggtgcga
     8881 aatctccagt aaatgggaca tcgccgtcaa tctgcgaagc tttccgtatg aactctcggc
     8941 tccacttcct tgctgcgcgc tggcccgccc tcgtgccggc gctcgccgcc gtcgtcctgg
     9001 ccctgacctg ggggcggtca ctgtccgccg gaacggtggc cctggtgagc tgctgcctgg
     9061 ccggcgccgt gctcgccgcc gtgcaccacg cggaggtgat cgcgcaccgg gtcggcgaac
     9121 ccttcgggtc gctcgtcctc gccgtcgcgg tgacggtcat cgaagtggcc ctcatcgtca
     9181 cgctcatggc cgacggcggc gacaagagcg cctccctggc ccgcgacacc gtcttcgccg
     9241 cagtcatgat cacctgtaac ggcatcgtcg ggctctccct cctcgtgtgc gccctccggc
     9301 gccgcgtggc cgtcttcaac gcggaaggca ccggcgccgc cttcgccacc gtggcgacgc
     9361 tcgccggact gagcctggcc ctgccgacct tcaccaccag cacccccggc ccgcagttct
     9421 ccccggccca gctcgtcttc gccgccgtcg cctcgctcct cctctacggc ctgttcgtgg
     9481 cgacccagac cgtacggcac cgcgactact tcctcccggt gaccgcccag ggcgaggtca
     9541 tcgacaccga cgaccacgcc gagccgccca cggcccggac cgccctgacc agcctcggac
     9601 tgctcgccgt cgccctggtg tcggtcgtcg gcctggccaa gggagtctcc ccgaccatcg
     9661 agtccggcgt ggccgccgcc ggcctccccg cctccgtcgt cggcgtcgtc attgccctgc
     9721 tggtgctgct ccccgagacg atcgccgccc tgcgcgccgc ccgccgcgac cgcgtccaga
     9781 ccagcctcaa cctcggcctc ggctcggcca tggccagcat cggcctcacc atccccgccg
     9841 tcgcggtggc ctcgatctgg ctggacggcc ccctcctcct cggcctcggc gcgacgcaca
     9901 tggtgctcct cgccctcacc gtcgccgtag gcaccctgac ggtgatcccg ggccgcgcca
     9961 ccccgctcca gggcggcgta cacctctcgc tcctggcggc ctacgtggtg ctggcggtga
    10021 gcccctgagg gacacgggcg gggacggggg cggggatacg ggcggggacg cggtgcgcat
    10081 cggtcatcca ggcggcggtg tgccggctgg caggccgggg acgctcctcg tagcgcggcg
    10141 agatgaggtg gtactcgatg ttgccgctca gccaggagcg cagcccgcgg gtcaggtgac
    10201 cgatgcactc gcgttcttcg ggggtgacgt cgaggtgggc gcagaggtcg ggcagcgcgc
    10261 gctcgagggc caggaaggag tgcatgcgct ggtcggccat cgtgacggcc cgggcgatcg
    10321 cctcctcctg ggtgcaccgg tactggcgct ggatgagggg aacgacgttg atgtggtcgt
    10381 tccaggaggc ttcgcggtgg acgccggtga tgtcgttgac gagggcgatg tggtcgcccg
    10441 tggcgcgctg catggcgtgg aggacggggt gcatgacgat gtcgtcgctg agctcgcagc
    10501 ggtgctccag gtcgttgaag cacatgttgg ccagggcggc ggtcgaccag atccggtcgt
    10561 ccaggtagtg ctcgaccgtg ggccagacac cgtcacggcg gtagaccgcg tcgcggaggt
    10621 acgaatccag gaagcgactg aaccggttcg cggtgcggcg ctgccagcga actgacatgc
    10681 cgtgggcctg ggtgcgccgc cacaggtcgg acagggccac ggtgaacggc ccggcgcagg
    10741 cacccggcgc gtcggggtca ttggtgtcga agatctgctt catttcgtcg acggtgtcgc
    10801 ggatgagctc gggatcgtgg acttccagga cgtcgtcgag catgacgccc cacgtccccc
    10861 agtcggtgac gaggtccagc aggtcgccgg tgcagtacca ccagacgcac gagccccaga
    10921 ggtccagccg gtaggcgtcc cagagggctg ccgcttccgg agaggccgcc atgcccgtct
    10981 cctggcacca ttcccaggta tgggcgcggg cgcgctcggc atcggggctg atccgcaggg
    11041 gaagcgggca gaagaacaga ttcagtcgtc gcatctccgt gcctccgttc cgggcgatcg
    11101 atcaggggct cggctcgctg tagaactgac cggcccagcg gcggtattcc atgatggggc
    11161 cgtccccctt ggtcagtttg ggatgggcta cgtacgcctt gttctgccac acggggaagt
    11221 ccttcgccat atcgagaccg atcagcgggg cgagcacttt gccgatcagc cgggtcgtgc
    11281 ggcccggggc ggtgaggccc aggcattcct ccacgttcac cgcgagcctg atctccacgc
    11341 gcagcggatc gacgggcacc ggcaggaccc agaaatggac gtgggtgcgg agccgcggaa
    11401 tgcgagcgtc gacgaacagc cagccgagcc cctgaagacg cagactgtag tggacttgat
    11461 gagataccag gaagcccccg gaagagccct tggccggagt cgtggccaga tcggcttcca
    11521 tcacggtccc tgaaaagcgg aggcccttga tgtcgatggc catgccgtga atgggagggc
    11581 cgtgtgcggt atcgacggag ttctccatga cgtcctgcgg gtggtcggcc agcgtgtagg
    11641 agacgtgccc cgccggacag aactccgcgg gcttggagga gcgcacttcc catgcggccg
    11701 ggtgaccgcg ggaatggtgc cagaccagca cgatgccgtc cgtctcgcgc acctccagca
    11761 gcctgagccg ggctttgggc ggtggtgagc cgcaccccgt tcggacgcag tcgccggagg
    11821 gcgagaaggc gaaatggtga aacgggcaga cgatgttctc cccgtccacc cgtccgccgt
    11881 ggccgagatg ggcccccagg tgcgggcaga acgggcgtac cgctcgcacc aggccggacc
    11941 gggtccggta cagcacgacg tcctcgccgg tgaggtgccg ggtcagcacc cggccggcag
    12001 gcaattcgtc gcggaatgcc acggcgtacc agccgtcggg ataaggcagc cggggagttg
    12061 ccctgttacc cgtcaccaat ggggtttcac ccgtgctgcg cgcgaggtga aacctgaagg
    12121 cggagggtat tttcatgagc gataccgtcc tcgtcgacag gggtcaactg ccgttggtcg
    12181 atctaccgca ccatggtggg acctgcagga tgacgttccg cgccgaaacc ggcaaccttt
    12241 cggttcgccc agcggaccac tcgcttgagc ggaaggcagg atgccgcgta aaagaggggg
    12301 ccatgtgctc cgatcagccg ggcgagaact ctcctgtgcc agccggtatg acgaccggat
    12361 cgacgaccga tgcaatgacc cgaacaacgg ccggtggagc gagcggcccg gatcggccga
    12421 ccgcgcgccg tatccgggag gcggtgggcc ggctcatggc cgggctcggg gacacgggga
    12481 cctgttcgga cagttacaac acggcattcg tctcccgggt ccgtgacccc gacggatccc
    12541 cgcgctaccc gcgcgcgctc caatggctgc aggagcgcca gcacccggac ggttcctggg
    12601 gaggccggat agccctgccc gccgaccggc tcacgtccac attggcggcc gtgcgcgcac
    12661 tcgtggacta cgcggagacc acgccgcccg ggccgtacga ctgggtggcc ggagcgctga
    12721 agaggggaac cggccacctg aagtcactgg cccgcgaatg gcgggccggg ccgcacgagc
    12781 cgatcggatt cgaattcgtc gtgccggagc tgacccgccg gctccgtgcc catggcgtgg
    12841 acctcccacc gcaggcatgg ccggacatcc acgccctgcg ccgggacaag atcgccagga
    12901 tggcagccgc ttcggcgggc tcgctctccc cctcgctctc cccttcactg cggtactgca
    12961 tggaggtcgc tccggacgag gccttcgcgg gagtggcact gacactgcag tcacccggag
    13021 ggtcggtggg ctgctccccc gcggctacgg ctgccttgtg gcagagcacg ggtgatgcgc
    13081 gggcactcgc ctacctcgac cacctcgccc accgctcgcg cgacggcggg gcgcccgagg
    13141 tgcacccggt ggaggccttc gagaccggct ggtccctcta ccacctcgga cgtgcgggcc
    13201 tgttgcctcc cggtgccgcg cagcacctcg atgcgctggc gggtgagctc gaccgccgcg
    13261 gctgggtcgg tttcagcagg gagtttcccg cgcccgaggc cgacaccact gcgatgacca
    13321 tcaacctgct gtcccacctc ggcgtggagg ccgcatcccg gctcggcctc ctcctgcgct
    13381 acgaagcaga cgatcacttc ttccactacc cgggcgagcg gggcgcgtcg gtgagtgtga
    13441 acgcccggct cctggaagcc ttcaaccacg cgcccggcat gtacggcccg cagcgccgta
    13501 agctcatccg cttcctcctc gagagccgtg cggcggacgg ctcctggctg gacaagtggc
    13561 acatgtcgcc ctactacgcg actgcccacg tctgcttcgc gctcggccgg tccgcatccg
    13621 ccgagggccc cttgacccgc acccacgagt ggctcctcga cacccagcat ccgaacggct
    13681 cctggggagc cggcggggga cagccggagg agaccgccta cgcgatcctg gcgctggacg
    13741 cactcgccgg aagcggcctc cctctcccgg ctcgtacgtc acacctggcc caccgctacc
    13801 tcgtgcccca tctcgatgcc gggcccgacg ccttcgccga actgtggctc ggcaagtccc
    13861 tctacacgcc gaccgcggtc gtgcagtcag ccgtcatcgc cgccgcccat ctcacgcggc
    13921 tccgcctcac cacgccgcgg gcgcgcggcg actgactccg ccggcgaggg cagggagtcg
    13981 gtgttcagcc ggcgcagggc gatggtgagg gcgaacgccg tgcgccggag ttcaccgacg
    14041 gcccgcttca gcgcggtgcg gcccgtggtg tcaccgatga ccacaccggc caggacgaga
    14101 cggtccggcc ccaggacggg cgcggccacc gtcagcatcc cggacgcgta ctcctgacgc
    14161 tcgacggcga tgccggtgtg gcggatgacc gcgagttcgt cctccagttc ctcgtggggc
    14221 ggccagtccg ctgcctgcgc atcgtgttcg aaggcgagca gcagcttgcc gatggcggtc
    14281 gaggacgccg gcaccgtttc gccggtgcgg gagagcagag gctgcaggcg gcggccgtga
    14341 atgcgctcca cgtagcggac ctgccggcct tcgtggactc ccaggcccac gaagccgccc
    14401 agggagtcgt acaggtcgag gaggaacggc attgccgtgg ctctcaggac gctgagctgg
    14461 ttccggcggg tgacgcgctt cgacgccagc tcggccagcc gctcgcccgc cacgtacttg
    14521 tcgtcccagc ggccgatcat tccgtgtgcg cagagcgccg tcaggatccg gtacgtcgtg
    14581 gccttcggca cgcccgtctc ccgggcgatc tcactgagcc cgcgcggcct ggcgtcctgg
    14641 cagaccatct ccagcacgcg cagcgcgcgg ccgaccgcgc cgcgttcgaa agtcgcttcc
    14701 gggatcgtcc tgacctccgc gggggtttgc gggtcccacc ttgtctgcgt cattccggac
    14761 aacccctact ggtcaggcac ggcgggcgat gacgcgcatc cgcagtcccc gggggcccag
    14821 ggtgactttg gcggagggcc gtacggggcg gccggagagc gggacgagac gccagcgggc
    14881 gttgatggcg gtgagggcca aggtggcctc ggccacggcg aagcgggcgc cgatgcactt
    14941 gcgggcaccg gccccgaaag ggaggtagac ggtgcggtcg ggctgcggcc cgcgccaccg
    15001 gtcggggtcg aagcggtcgg ggtcctcgta caggtcgggc cggcggtgga tgaggtaggg
    15061 gctgaaggcg atcagggttt cggccgggag cgtgaccccg ccgagctcgg tgtcctccac
    15121 cactgtgcgc gtgagcagcc acgcgggcgg atacagccgg agagcctcgt ggacgacgtg
    15181 ccccgcctcc tgcagggcgg gcaggtcggc gaaggccggc gaggcgccgc ccaggaccct
    15241 ggcggactcc gcgtgcaggc gttcttccac ctccgggtgt tcggcgagca ggtacagggc
    15301 ccaggccatc gcgttggagg tcgtctccgc tccggcgagg aagaacgtga ggacctggtc
    15361 ggccagttcg gcatcggtca gtgcccgggc gccgtcggcg aggctgtcgg ggtcggtggc
    15421 actctgcagg gacgaaagga ggtcccggtg gtcggtggaa tcggcgctgc ggcggccggc
    15481 gacgctggag gccgtgtgct gcagccgctc gcgtgcccgg aggtaacgcc ggtttcccgg
    15541 actcggcagc cggttgagga gcgcaggcct gatcatccgc cggaacgcgc cgttcaccac
    15601 ggtgttgatg tcgccgaccg tctgctgcgc ggcctcgggc ggcagggcgg cggtgaacat
    15661 cgtctccacc gcgacccggg tggccagttt cgtcatctcg gtcgtcacgt cgacgacctg
    15721 gccgtcgtgc caggagcgcg ccacgccctc ggccgcggcc acgaacaccg cggaatagtg
    15781 ggggaacctc tcggggtgga aggacggctg gcacagccgc cgctggcgcc tgtgcctgct
    15841 gtgcgggcac gagatgaggc cgtcgctgac cacttcgcgc acccgctcgt acatgggacc
    15901 ccccttgtcg aacacgtggt cgttcaggag gacctgccgg gtcaggaccg ggtcgcacac
    15961 catcacgacc gaccgcggcc ccatgcggat ccgcaccagt tctccgcggg cgggcaggga
    16021 cgacaggaac gccagcggat cgcggacgag gggcagcacg tgccccagga gcggcacggc
    16081 attcggtgcc agtggaatcg acgcagccgt atccatgccc accccttccg ggacgagtcg
    16141 ccgggacgcc gggacgcgta gggacgccac cagcatgttg tccaccctgc acggctcgtg
    16201 aatccccggt cgtgcggtgc acgggagcac acccggcgga ctgaaaaggc ggaggtgcgc
    16261 cgcgcacttc atgtgcgcgg cgccgtagcg aaacggagga ggagccgggg cggtggtgac
    16321 aaccggcagc gttcaggccc tgggtttggt ccagacctat tgacggttca acggggcggt
    16381 cctagcgttc gacaccttca gcgaccggtg gcgggcagcc acggcccgaa gggagccgag
    16441 catgatcggt cggatggcgc gtctgctggc gggggcggcc ggggtctgcc tggggacggt
    16501 cctcgcgggc cctgcgcccc tgcagacgga gagtcaggtg gcgtacggga ccgccgccgc
    16561 ggtgagcggg ccgggggcgg acacctgtcc cgtgcagtcg aggccctcgg gcaaggtgct
    16621 ccagggctac tgggagaact gggacggagc ggcgaacggc gtgcacccgc cgttcggctg
    16681 ggtgccgatc accgacgcgc gcatcggcga gcacggctac aacgtgatca acgcggcgtt
    16741 ccccgtcatc cgctcggacg gcaccgttct gtgggaggac gggatggacg cgaccgtgaa
    16801 ggtcgcgacg ccgaccgaga tgtgccgggc caaggcggcc ggggccacga tcctgatgtc
    16861 gatcggcggc gcggcggcgg gcatcgacct cggttccggc acggtcgccg accggttcgt
    16921 ggagaccgtc gtgccgatcc tcaagacgta caacttcgac ggcatcgaca tcgacatcga
    16981 gaccggtctc accggcagcg gcaacatcaa cacgctgtcc gcctcgcaag ccaacctcat
    17041 ccgcatcatc gacggcgtac tcgcccgcat gccctcgaac ttcggcctca cgatggcccc
    17101 cgagacggcc tacgtcacgg gcggcagcgt cacgtacggc tcgatctggg gcgcgtacct
    17161 gccgatcgtg aagaagtacg ccgacaacgg ccggctgtgg tggctgaaca tgcagtacta
    17221 caacgggaac ctttacggct gctccgggga ctcgtactcc gcggggacgg tgaaagggtt
    17281 caccgtacag acggactgcc tgaacaaggg gctcgtcgtc cagggcacga ccatccgcgt
    17341 cccttacgac aagcaggtcc cgggccttcc cgcccagccg ggcgccggcg ggggctacat
    17401 gtcaccgggg ctcgtggcgc aggcgtggaa cacctacggc aacgggctga agggcctcat
    17461 gacgtggtcg gtcaactggg acgggtcgaa ggggtggacg ttcgggaaca acgtgcgggc
    17521 gctgcagggg cgttgagccg tcgcaaggcc ccggtgcctc cggcatagcg ttcactctca
    17581 gttcattgca acgagagagg tggctttcgt tgcgttacgt tcagggctgt tgcaacgatc
    17641 tttacgccct gacctgcggt gatgttgttt ttgcgcaacg aagtcgttgc ggagctttgg
    17701 aatgcaacgt agcgtttccc ttgttcgaaa caacgagtcg caggagaaca tcatgcagaa
    17761 gttccacacc cccgccgccg tcgccgccgt cctcgacatc cccgccggac gcatccgctt
    17821 catcgcagcc gaccgcaccg acaccaccgt cgaggtcctg cccgcggacg cctccaaggg
    17881 ccgcgacgtg aaggccgcgg agcggaccac cgtcgaatac ggcgacggcg tcctgcggat
    17941 cgcggacccg gcggcggaga cccggaccct cggcaacccc ggatccgtcg aggtgaccat
    18001 ccagctgccc gccggctccc gcatcgaggc gaagaccgcc accgccgaga tccgcggcgt
    18061 cggacgcctc ggcgacgtca ccctcaacag cgcccacggc tccatcaagc tcgacgaaac
    18121 cgcaaacgcc cacctcaccc tcgccgccgg cgacatcacc gtcggccgcc tgggcggccc
    18181 cgcccagatc agcacccaga agggcaacct ccacatcacc gaagccatgc acggcaccgt
    18241 caccctgcgc accgaggccg gcgacatcac catcggcgcc gcccgcggag tctccgcctc
    18301 cctggacgcc ggcacctcct acggccgcat ccacaacgcc ctcaagaaca ccgacagcac
    18361 cgacacccag ctcgacatcc acgcaaccac cgcctacggc aacatcaccg cccgcagcct
    18421 ctgacccaca gcctccgacc cacagccctt gccccgcagc ctctgactca cagcctccga
    18481 cccggtgcgc ggcccgttcg ccgccctccc ataccctcat ctcccctgcc gtgagggcac
    18541 caccgcggca tcgcaaatac ctatgagcaa caccgaagaa ggacaagaaa aatgagcacc
    18601 actcaggact accaggccgc cgagcagctc ctccgccgcc ccgcccgccc tggcgagctc
    18661 gtcatcggcg acaaggtcag gccgcagtgg atcgacggag gcgcccggtt ctggtacgcg
    18721 gtgagcaatg gcgtcggcag acggttcgtg ctcgtcgacc cggcggcggg tacccgtgag
    18781 ccggccttcg accacgccct gctcgccgac gcgctggccg ccgcctccgg gcagcaggtc
    18841 gaccccgagg ccttgccttt cataggcatc gaactggccg ggaacgccgt ggagttccac
    18901 gcgttcggcg agtactggcg ctgccgcctg gacggctacg cctgtgagcg ggccgagttc
    18961 acgccgccgg gcagcccgct ggacgtgctg tcacccgaca agaaggtcgc ggtgtcccag
    19021 cgggggcacg acctgtgggc gcgctcgcta tccgacggcc gcgagtgggc gctgaccacc
    19081 gacggggagc ccgaccaccg gtacggctcc ggcccggact gcacgagcaa cggcaccctg
    19141 ctgcgcaaga tcggcctgcc gcacctgccg cccgcggtgg cctggtcgcc cgactcgacg
    19201 aaggtgctgg cgcaccggac cgacgagcgc ggcgtccggc agacccacct cgtggaggcc
    19261 aggcccgccg acggcggcgc gcccctcctg cacacccagc ggtacgcgta ccccggggac
    19321 gagcaggtgc cccaagccga gttggtggtg ctggacgtgc aggcgggcac catggtccgc
    19381 gcgcaggcag cgccgctgct catgccgcag ctgtcgccga tcacgacgaa gtgggcgtgg
    19441 tgggcccagg acggctcggc cgtgtactac ctcagccggc cccgcgacct gcgcacgctc
    19501 acgctgcacc ggctggatcc ggccaccggc gaggtcacca ccgtgctcag cgagaccggg
    19561 gccacccgcg tcgagcccaa ccagtggatg tacgaggcgc cgatcgtgcg ggtgctggcc
    19621 gacgaggtgc tgtggtactc gcagcgggac ggttggggcc acctgtaccg gtacgacctg
    19681 cgcaccggcg agctgctcgg gcaggtcacc tccggggagt gggcggtgcg ggagatcctg
    19741 cgcgtcgacg aggccgagcg ggtggtgtac ttcaccgccg tcgggctggt cgacgaggat
    19801 ccgtaccggc gcacggtgtg ccgggtcggt ctggacggct ccggcttcgc caaggtcacg
    19861 gacgacgagc tggaccacgt cgtcaccatg ccggacgacc aggagtactt catcgactcc
    19921 gcgtccacgg tcgacacccc gccggtgacg acggtccgtg accggaccgg gcgggtgctg
    19981 gtcgagctgg agcgcgccga catcagcaag ctcactgcca ccggctggac gccgccggag
    20041 cggttccgcg tcaaggcggc cgacggggtg acggacatct acggggtgct gtaccggccg
    20101 cgggggttcg accccgcccg gcgctacccg gtggtggaca acctctaccc cggcccgcag
    20161 gtcaaccggg tcgccccgtg cttcgacccc ggcgggatgg gcctcgacgc ggaacccctc
    20221 gcggcgctgg gcttcgtggt ggtggcgctg gacgggcgag gcaccccggg gcggagcaag
    20281 tccttccacg acgcctccta cggccgcttg gccgacgcgg gctgcctggc cgaccatgtc
    20341 gcggcgctgc ggcagctggc cgggacccgg ccgtggatgg acctggaccg ggtgggcgcg
    20401 ttcggccact ccggaggcgg attcgccgca gcgcgggcga tgctggactt ccccgaggtg
    20461 tacaaggccg gagtcgccct ctcgggctcg cacgacgccc gctgcttcaa cctgggcttc
    20521 gtggagacct acgacggcgc ggccaatccc gaggcctggg cccgctcctc caacgtggac
    20581 ctcgcggacc ggttggcggg caagctgctg ctcgtccacg gcgaaatgga cgaccaggtc
    20641 caccccgacc acacgctgcg gctggccgac cggctcatcg ccgccgacaa ggacttcgag
    20701 ctgctcatcg tgcccggggc cgagcacacg ttcatcgact gcctggccta cgtccgcaag
    20761 cgctgctggg acttcctggt gcgcgagctg atgggcacgc agccgcccgc ccaccgcccc
    20821 gcccccatcg ccatcggccc cgagctgctc ggcgagctgt tcgcctgagc gcgacaccca
    20881 ttgaggcggg ggcatcggag aaaggagatg ggccggttgg gccggactgc gtaagggttc
    20941 ggtcatcccc ggtcatcggc cgccgccgtg cgtggcgtgc ccgaggtctc ccgccgggtg
    21001 ggcccagaat ctccgtgttc gtcatccgga acccggaacc cgggagccca ccatggtcct
    21061 gaaggtgctc gctcgcacac tggctctggc cgcgctgctc gccgtgcccg cgggggtgtg
    21121 cacggcggcg ccggcgcccc ccgccccgtg ggtgcctccc gccccactcg tgcctcctgc
    21181 cccactgatg cctctcgccc ccgcccgcgc tcccgccccc gcaccggaag cggccgtgac
    21241 gcagcgctgc gcccccgccg ccgtgctcaa gggaaagggc acgggcaagg gcgggcagtc
    21301 ggcgaaggcc ggcgtgtgcg tgacgctcga caacgcgttc atgaccgtca ccgcacccgc
    21361 cgagtgcggc cggggcacct gtgacacgtc agggacctgg cggatgaggc gcggcggccg
    21421 ggaagtcgcc tcgggggagc tcgcccggcg ggcggggtat ccggggccgg ggacgtacga
    21481 gatcaccacc acgctacggg tgcgctcggt cccggcgggc gtcgacttcc gggcggagag
    21541 gaccgtcagg gtcaccttgt cctggccccg ccccaaggcg acgcaccgca tcgacgtcag
    21601 cccgcgcacg gtcagggcgg gccgcaccac gaccgtgacg tacacggtca gccgcctggg
    21661 gcccgacggt gacagcaacg cccgcctggg cctgatcggc gtcgagaaga caggggtgca
    21721 gctgacctcc tccgatcccc ggtgcagcaa ccccctgtcc ggcgcctacc cctccgaggc
    21781 ccgccacccg tacgtcctga actgcgactt cgtcgaactc cagcccggac ggccgggcgt
    21841 ggtcaaggta cgggtccgca tgggcgaggc ctgctcgccc gtcgtctcca agatgggcta
    21901 ctggctgccg aaggggcagg agacctacac gggcaacatg ctcgtggggc cgacggtcgg
    21961 gtgcgtgaag ggatgagcgc gggcggcgag ggtgttctgg cccgggcgca cgtggcgacc
    22021 cggcttccgg cccgggacct ggaccgggcg cggcgcttct actccgagca gctcggactg
    22081 gagcccgtcg acgagcggcc cggtgggctg ctgtaccggt gcggaggcgt ggacttcgcc
    22141 gtgttcctgt cgacgggggc ctcgtccggt gagttcaccc agatggcctg ggaggtagac
    22201 gacatcgagg aagccgtggc ggaactgaag cggcgcggcg tggtgttcga agacgtggag
    22261 ctgcccgggc cgccgggggc gccggccgcc gggcggacgg aggacgggat cgtcgacatc
    22321 gacgggaact acccgagcaa gggtgcgcgg ggcgagcgcg gagcctggtt ccgcgacagc
    22381 gaagggaaca tgctgggcat cggccagccg gtcgtctgag gaggacggcc cgccgccccg
    22441 ccgccgacgg cccgtccccc gccgaccacg gcccgccccc gccgtggcgt gaaaccgtaa
    22501 gcggaagatc tcaccccgcg cagcgcctat ggttgtcgga ttcgccgatg ttcgaatctt
    22561 gcacagctga agggcggtcg tgcggtggtg ctcgcgcgtg tcgagttcaa ggtgctgggg
    22621 cccctcgcgg ccgtcgccga cggccgcgtt ctcccgctcg gagggccgaa gcagcggacc
    22681 ctgctcgcca tgctcctcgt caacgccaac accgccgtct ccgcggaccg gctgtgcgac
    22741 gccgtctggg gcgaggcccc tccggcgtcg gcccaggcca acctccgcag ctacgccgcc
    22801 gtcctgcgca aggtgctcag ccccgcctcc ggcccggagg acggccgcga ccgcggtggc
    22861 cccgcgcccg gcagcggcga ggaccggctg agccagggca acggcggcta ctgcctgcgg
    22921 gtgttccccg gcgaggtgga cctgcaccgg ttcgaggtcc tcgtcgcccg cggccgcgtc
    22981 gccctcggag cgggcgagcg ccgggcggcg gccgacgccc tgcaggaggc gctggacctg
    23041 tggcacggca gcccgttcga aggggtggcg caccacgacg tcctgctcgg cgaggtcgcg
    23101 cggctcgagg agtcgaggct ggccgccttc gaggactacg ccgaagcccg cctcgcactc
    23161 ggcgagcccc gcgaggtggt gggcctcctg cgcgcggaga ccgcccgcta cccgctgcgc
    23221 gagtcgctgt gggccaagct gatgaccgcg cagtaccgct gtcaccaccc gggcgacgcg
    23281 ctgcagtcct acgccctcgc ccgctccgcc ctgcgcgacg aactcggcat cgaacccggc
    23341 gacgaactcc gcagactgca tcacgcggtc ctcaccagag acccggaact gggcgcgccc
    23401 ccgccccccg cggcacccgc acagcccgcc cgccccgcgg acctctggca gccgaccgtc
    23461 caagtcccct ccgacgactc cgacttcgtc ggacggagcc ggctgatcga gcacgtggcc
    23521 gggctgctca gacccgggcc cgaacggccc cgcaccacgc cctgcgccgt gcccgtcgcg
    23581 atcctcaccg gcctgccggg cgtcggcaag accgccctgg ccacccgcct cgcccaccac
    23641 ctgcgcaacg agttccccga cggccggctg ttcctgcacc tcgacggcac ccgcggcccc
    23701 cagcgcccgc ccggcgtcat cctcgcggac ctgctcctca gcctgggcgt cgccgggtcc
    23761 tccatccccg aggccacgga ggaccgggcg gcgctctacc gctcgctgct ggccgaccgc
    23821 aaggtgctcg tgctgctcga cgacgcgcgc gacgaggccc agatccgcct gctgctcccc
    23881 ggcaccccgg gcagcgcggc cctggtcacc agccgggcac ggctggccgg gctgacggac
    23941 gcgcgcctga tcgac
//
