LOCUS       NZ_LNBE01000003        13588 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces roseifaciens strain MBT76 scaffold_3, whole genome
            shotgun sequence.
ACCESSION   NZ_LNBE01000003
VERSION     NZ_LNBE01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseifaciens
  ORGANISM  Streptomyces roseifaciens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 2630732)
  AUTHORS   Wu,C., Zhu,H., van Wezel,G.P. and Choi,Y.H.
  TITLE     Metabolomics-guided analysis of isocoumarin production by
            Streptomyces species MBT76 and biotransformation of flavonoids and
            phenylpropanoids
  JOURNAL   Metabolomics 12, 90 (2016)
   PUBMED   27073352
REFERENCE   2  (bases 1 to 2630732)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     The complementarity of genome-mining and NMR metabolic-profiling
            facilitates lead-finding
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 2630732)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2015) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.06
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001445655.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 03:28:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,528
            CDSs (total)                      :: 7,450
            Genes (coding)                    :: 7,245
            CDSs (with protein)               :: 7,245
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 205
            CDSs (without protein)            :: 205
            Pseudo Genes (ambiguous residues) :: 0 of 205
            Pseudo Genes (frameshifted)       :: 77 of 205
            Pseudo Genes (incomplete)         :: 168 of 205
            Pseudo Genes (internal stop)      :: 20 of 205
            Pseudo Genes (multiple problems)  :: 56 of 205
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:37:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1038071
            Orig. end                         :: 1051659
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LNBE01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..13588
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="aminopolycarboxylic-acid"
                     /region_number="7"
                     /rules="(AesA and AesB and AesC)"
                     /tool="antismash"
     cand_cluster    1..13588
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AesA and AesB and AesC)"
                     /kind="single"
                     /product="aminopolycarboxylic-acid"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..13588
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8588](+)"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8588
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(AesA and AesB and AesC)"
                     /neighbourhood="5000"
                     /product="aminopolycarboxylic-acid"
                     /protocluster_number="1"
     gene            complement(184..1029)
                     /locus_tag="AS857_RS10350"
     CDS             complement(184..1029)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006138032.1"
                     /locus_tag="AS857_RS10350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease subunit"
                     /protein_id="WP_058042822.1"
                     /transl_table=11
                     /translation="MSSAALAPYRSRRPPVRVLLAVAPGLLLTLLALTGPLYAPRTEAS
                     PVTAPYAPPGRDALLGGDQLGRDVLSRMLHGGSALIGSALAVALLVTALAAVLGCFAVL
                     TPALGRLVERSADVAILLPPVLGMMLIALAWPGGGRLAVMAAATVLGVPYAVRVVASAA
                     APVAAAGFVEAATASGERLWHLALREILPNLRSTVLALFGLRFVAAVYVISMAGFLQLG
                     PQPPAADWALMIRENAPGALLNPWAVVAPSIAIGLLAVSVNLAADALTPAARRAGAGVR
                     "
     gene            complement(1026..1916)
                     /locus_tag="AS857_RS10355"
     CDS             complement(1026..1916)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014173874.1"
                     /locus_tag="AS857_RS10355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_107105614.1"
                     /transl_table=11
                     /translation="MLGVLLAVVFAAIELLPGDAASATSERGESAADTAARRHLLGLDR
                     PVWERFGDWMTALPTGDLGTSARGERVTGLLAAPFPNTLLLGATAFALTFAAALALGCR
                     AALHPGGTVDRIIGFTSGIALALPEFVVSVGLLLVLSLWTGWLPAVTLTAPDGSPASWT
                     MLVMPVLALTVPQAGWNARIVRGALADQAGAPHVAAARLDGLSPRRVLLRHALPGAWPA
                     IATGAATSTGMLLGGAVVVETLFNYPGLGTVLSGAVADRDTPVIAGVVACTGAVISLVL
                     LCADLVRARTLGARP"
     gene            complement(2030..3583)
                     /locus_tag="AS857_RS10360"
     CDS             complement(2030..3583)
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006138034.1"
                     /locus_tag="AS857_RS10360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_058042824.1"
                     /transl_table=11
                     /translation="MNWTRRQALWAGGSIGAAALLTACGGGENDAASSPADSAGTPRKG
                     GTLRIGALGRASATTRDPHGTQGNESDYLIIALVYDTLTAPGLKDNTVGRLASGWTPSG
                     DLKTWRFTIAKGAAFHDGSPVTADDVVWSLRRLRNTPAGAARLPGIKAENITAGGKDTV
                     VLVSDQPNAELPLLTRLSTFVLKKDTPDKEIAGAPGTGPFKLDWFRSGNARLLRNDKWH
                     GGPVHLDAIEVTMFESPQAMANALLGGQIDVASNVGAVAARSAASRKDIQLVRRPNDMA
                     MPVVMRAADGPFADVRVREAMKLVVDREAMVKQVLSGYGTVANDILGTGDPAYAKDIPQ
                     RSRDLAKAKKLLAEAKFDLSKTYELVTTEDVPGLAESATLFADQAREAGIKIKVVKQES
                     GAFYEKTWLKGQLYTNYWGTNDSVVFFASKTMVTGAGQSEAGWSDPQFDAVYRKVIGTA
                     DKKARATALRELQQIEHDKSGYLLWGMADGIDLAGPKVRNLPKLPGYGRVQLENVWLTR
                     "
     misc_feature    complement(3615..3633)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 27.16"
                     /tool="antismash"
     misc_feature    3744..3762
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.25"
                     /tool="antismash"
     misc_feature    complement(3749..3767)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 30.9"
                     /tool="antismash"
     misc_feature    3759..3772
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.55"
                     /tool="antismash"
     gene            3937..4929
                     /locus_tag="AS857_RS10365"
     CDS             3937..4929
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091641.1"
                     /locus_tag="AS857_RS10365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_058042825.1"
                     /sec_met_domain="TauD (E-value: 2.2e-08, bitscore: 31.3,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTGAPPVRRLDAASSAELHRTAGEILAAFGTSATSPELLRRIAV
                     SAADLAGTIREHLRPVDTDDGLFVLRGLTVDDTRIGPTPASWAEAGDSAAGHDIVMLLL
                     AAAMGNPIAWKGQQGGRFVHNIVPAVGHEQAQTGASSDILLSPHTEDAFHPGRAHLLML
                     GCMRNHDNIATTAASIRKVRLEDADIATLSRPELPILPDDAYFEAQGFAGEPPDVPTLW
                     RSEDGLTLRFDPAYTPLEKATPAYRAAYERLEAELARVSVAVSLSPGEVLVVDNDLVVH
                     GRVPFKARYDGTDRWLKRASVRVPGRGTRPPAEDAEHGYGQAVTKAYAA"
     gene            5001..6026
                     /locus_tag="AS857_RS10370"
     CDS             5001..6026
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091640.1"
                     /locus_tag="AS857_RS10370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="WP_079110215.1"
                     /sec_met_domain="AesA (E-value: 4e-164, bitscore: 542.0,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTAADPCISGTPADDTTLRVLSTGDLAGIDITLADVVGTVEGA
                     YRTLAAGLSDNPRKLTVKPADGHSVAYAMLGRDGSRDVVAVKTSYKHGLDKGRQEQHYY
                     TTLTLYDDVTGLPVAMMDCSRIGSLRTPAVSALLARECAAPGARSALVIGTGTQGRLAL
                     PFLLTTLPGLDRLMLFGTHPEGIEAVRAQLHAHFPDRDVEVVADVRAAAGDADVVVATA
                     GAHTPAAVEAEDLAPGTLAILVGHGLDPSTLHRADRIVATSEAQMNVTGTDMADAEGKL
                     PAVDTEFPPVLAGAAAGRTAPTERIFAYNSGLVVTDIALGHRFAQLALAQGLGTQVPLW
                     R"
     gene            6017..7474
                     /locus_tag="AS857_RS10375"
     CDS             6017..7474
                     /EC_number="5.1.1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010987018.1"
                     /locus_tag="AS857_RS10375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alanine racemase"
                     /protein_id="WP_063804220.1"
                     /sec_met_domain="AesB (E-value: 8.6e-185, bitscore: 611.2,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 3.1e-24, bitscore:
                     82.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVNGTPPPPPSLPAHPDPATDAVLGSGLLHELAHAFGSPFHFLL
                     PHRFDANLAAFRAALADAGVDGRVYYAKKANKAAAWVERCAAAGAGVDVASPGELREAL
                     GHGVRGENIVVTGPAKSEELLRVAALQGALTAVDSLDELDRLTAAPRAGGAPPPRLLLR
                     VLPPAQPGSRFGLDGAELEEALTHCARAGDAVRMEGFGFHLSGYAVQPRADLAGHLVDL
                     CLKARVMGLRADRISIGGGFAVDYSAADDWHSFLAAQQPGHYHAHRRFTPADFYPYHSP
                     VAGADALRAVLAAVPAGGRDSLGSRLRETGTLLLMEPGRALLDRAGCSVFRIQGVKDRD
                     GYAILTVDGTSLSLSEQWFNSEFLPDPVLVPTAGRAGRTRRTGGTGGTGVHPACAGGAT
                     CLESDLLTWRKIPFPVRPSVGDLLVYPNTAGYQMDSNESPFHDLPLPPKVVVDTTDDGT
                     DDGTDGTTDGTTGGGRPRWRLDRRPAC"
     gene            7563..8588
                     /locus_tag="AS857_RS10380"
     CDS             7563..8588
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0006535 - cysteine biosynthetic process
                     from serine [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     aminopolycarboxylic-acid: AesC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006138038.1"
                     /locus_tag="AS857_RS10380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cysteine synthase family protein"
                     /protein_id="WP_058042826.1"
                     /sec_met_domain="AesC (E-value: 1.2e-176, bitscore: 583.8,
                     seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="PALP (E-value: 5.1e-56, bitscore: 187.3,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEALMRPAVVSRISDLIGRTPLFELCRTDNGSRLLLKLEMYNPT
                     GTAKIRMARQMVLDAEARGELRPGGRIIESTSGNTGLGLAVVAAERGYAFTAVVDHHAC
                     SDKLRAMKALGTELVYVADDGTEELATAAREELAEEMARGRDNTVFTEQHNNPSNGVGY
                     HPVAHELHQALGGRIDVLIGAVGTGGSLCGTASELRRLVPGVRTVGVEPKGSIAFGGPA
                     HDYYQSGTGTPEGAEIGALVDFDLIDEGVKVGDVEAFATARAVARTGLLIGGSAGGVVH
                     EALSRLPSLPPGTTIVALVNDGGEKYMDTVFDDAWMNARNLTDPALEREIDEALTKLRK
                     G"
     gene            8597..10057
                     /locus_tag="AS857_RS10385"
     CDS             8597..10057
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0042910 - xenobiotic transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006855 - xenobiotic transmembrane
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1086: MATE efflux
                     family protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998466.1"
                     /locus_tag="AS857_RS10385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MATE family efflux transporter"
                     /protein_id="WP_173864740.1"
                     /transl_table=11
                     /translation="MDPTILLRDGRALAGLAVPLVLTQLAQVALTTTDTVMMGLLSTRD
                     LAAGGLALVIFNQLRTMGVGLVTSVGNRIAAAAARAETADGDPAQSDAEVRRIVRASMA
                     VATLAGLAGAVLMLLVGQALTLLGQEAAVADRVRTLLPALAPGLLPCLWFQAVRQFTVG
                     MRRPQALLQITLASVAVNAGLDWALIHGTWGLPKLGLTGIGVATSAVYLLSFLALYASA
                     RRDPALAPLLSLNVFAADRTTVRELVRLGVPIAATYGSEAGFFSVTALMAGSFGSAALA
                     AHTAVNQLVYIVFQVAVGLSHAASINVSRELALGRVHAALRIKNTALACAAAVMAAVGA
                     VYVTLPGLVLRPFLDGGAAGDDRAVTIATQLLLVVAVLQFFDCAQNIGVGLLRGLDDTR
                     SGFRITLVGYWAVGLPAAWLFGYAAGLDTLGIWLGLLAGLATTAVLLLRRYGSGLRARV
                     REQEAAATACPGPPAGRPLRRPSGADQG"
     gene            complement(10037..11545)
                     /locus_tag="AS857_RS10390"
     CDS             complement(10037..11545)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006601805.1"
                     /locus_tag="AS857_RS10390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FUSC family protein"
                     /protein_id="WP_058042827.1"
                     /transl_table=11
                     /translation="MLKRAFMAPDPGLGRLRIAVRAVLGVTFAVTVVQLSGLPLTASIT
                     GGLTALLALFTVADPTVRRQVNTTALLPVVGFPVLALAAGLHGLPLVRDAAFLAVVFCG
                     VYARRWGPRGNALGIFGFMMFFATQFLHAVPAQLPHLYTAMIMSLAAAGSVRFGFWCIE
                     RRTPPPAGPAPLAGRGLARVTTRQAFQTAFACGLALAVGQMVSDERWYWAVGTAWWIFV
                     NTASRGETLVRGFRRVLGTVMGIATGMVVALPLHGAPAATAALVAVCVFGIFYTAAVSY
                     TWMMFAVTVMAGLLYGLLGVLDADLLTLRLAQTGVGAAGAALAVLLVLPVTTHATTDAW
                     IQRALRCVHACAAEAAARLAGSETADPAPRVTELELLLGRVRLSLAPLVHPLNPFRARK
                     EKARRVVALLDDCAREVRGLASVAADPEASHDDRLAAACWRVETAVEALTTPGKARDAA
                     AASAAAPEHLPAEPALAHLHDLERALAELAAPLRSTRPSPLVGA"
     gene            complement(11779..12930)
                     /locus_tag="AS857_RS10395"
     CDS             complement(11779..12930)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1106: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="AS857_RS10395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_058042828.1"
                     /transl_table=11
                     /translation="MLWYALAVLLVGINMRPAIVAVSPLLDEIRHVTGLSNGGAGALST
                     LPLICFGIFAPLAPRLARRWGMERTLVAVLAVLLCGTAIRIVPSLFPLFAGTFLVGTAV
                     AVANVVITALIKRDFPQQVGLMSGLHTTMLVGGGAVTAAATVPLRDALSLSWAGGLSVW
                     GVLALAALVVWAPRLRRGREQPRVAAQAGGSIWRSRLAWAVALFYAFQSLLYYTATTWL
                     PSFYIDHGYTEGGAGVLLAVCMGSAMVTSLLVPVWAQRSRRQSYLAVGGTVLCMAAFAG
                     LIAAPVGAAVLWAVLLGLGLGAVLSLGIAYMSMCVRSTHDAGLLSAMSQCVGYLLAAVG
                     PTAFGAARDLTGAWTAGLIALVVLAVPMGITGALAGRGGHVER"
     misc_feature    12890..12903
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.18"
                     /tool="antismash"
     misc_feature    13040..13053
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.07"
                     /tool="antismash"
     misc_feature    complement(13325..13340)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.04"
                     /tool="antismash"
ORIGIN
        1 gggcgagtga gggctcgggg cgggtggatt cggcggcgga tccggcggcg gttcggagct
       61 ccggcgccga cgcgggacgc ggcacggatc cccgaagcgg ccctgcgcaa gtacgcggcc
      121 ctgcacaagc acgcggtcct gcggaagtac gcggctccac gggaacgagc cgttctgcac
      181 gtgtcaccgc acccccgccc ccgcccgccg cgccgcaggc gtgagcgcgt cggcggcgag
      241 gttgacgctc acggccagga ggccgatggc gatgctgggg gcgacgacgg cccaggggtt
      301 gaggagggcg ccgggggcgt tctcacggat catcagcgcc cagtcggcgg ccggcggctg
      361 gggcccgagc tggaggaagc cggccatgga gatgacgtag acggcggcga cgaagcgcag
      421 gccgaacagg gcgagaacgg tggaccgcag gttgggcagg atctcgcgca gcgcgaggtg
      481 ccacagccgc tcgccgctcg cggtggccgc ctcgacgaag cccgccgcgg cgacgggcgc
      541 ggccgcgctc gccaccacgc gcaccgcgta cggcacgccg agcacggtgg cggcggccat
      601 gacggcgagg cgcccgccgc cgggccaggc cagggcgatc agcatcatgc ccagcacggg
      661 cggcagcagg atggcgacgt cggcgctgcg ctcgacgagc cgtcccagcg ccggggtgag
      721 gacggcgaag cagcccagca cggcggccag ggcggtgacg agcagggcga cggcgagcgc
      781 gctgccgatg agggcgctgc cgccgtgcag catgcggctc agcacgtccc ggccgagctg
      841 gtcgccgccc aggagcgcgt cccggccggg cggggcgtag ggcgcggtga cgggggaggc
      901 ctccgtccgc ggggcgtaca ggggtccggt cagggcgagc agcgtgagca ggagcccggg
      961 tgccacggcg agcaggacgc ggaccggggg gcgccgggag cggtacgggg cgagggcggc
     1021 ggagctcatg ggcgggctcc cagggtgcgg gctcggacga ggtcggcgca gagcaggacg
     1081 aggctgatga cggctccggt gcaggccacg accccggcga tgaccggggt gtcgcggtcg
     1141 gcgacggcgc cggacaggac ggtgccgagg ccggggtagt tgaagagggt ctcgacgacg
     1201 accgctccgc ccagcagcat gccggtggag gtggcggcgc cggtggcgat ggcgggccag
     1261 gcgccgggca gcgcgtggcg gagcagcacg cggcgcgggg agaggccgtc cagccgggcg
     1321 gcggccacgt ggggtgcccc cgcctggtcg gccagtgcac cgcggacgat ccgggcgttc
     1381 cagccggcct gcgggacggt gagggccagg accggcatga cgagcatggt ccaggaggcg
     1441 ggcgagccgt cgggggcggt gagcgtgacg gcgggcagcc agccggtcca cagggacagg
     1501 acgagcaaca ggccgacgga gacgacgaat tcgggcaggg ccagggcgat gcccgaggtg
     1561 aagccgatga tccggtcgac cgtgccgccg gggtgcaacg ccgcccggca gcccagggcg
     1621 agcgccgcgg cgaaggtgag ggcgaaggcg gtggcgccga gcaggagcgt gttggggaag
     1681 ggggcggcga gcagaccggt gacgcgttcg ccccgtgcgg aggtgcccag gtcgccggtg
     1741 ggcagcgcgg tcatccagtc cccgaaccgc tcccacaccg gccggtccag gcccagcagg
     1801 tgccgccggg ccgcggtgtc ggcggcgctc tcgccgcgtt cggacgtggc cgaggccgcg
     1861 tcgccgggca gcagctcgat cgcggcgaac acgacggcga gcagcacgcc cagcatcagg
     1921 gcccgtttgg cgagcaccac gccggtgcgg gcggccgccg tcgcggcgcg gcgcagggcc
     1981 ggggccgccg gcggtgcggc ggccccggcc ccttctgacg ctgcctggct caacgcgtca
     2041 gccagacgtt ctcgagctgc acccgcccgt agccgggcag cttgggcagg ttgcgcacct
     2101 tgggcccggc caggtcgatg ccgtcggcca tgccccagag caggtagccg gacttgtcgt
     2161 gctcgatctg ctggagctcg cgcagggcgg tggcgcgggc cttcttgtcg gcggtgccga
     2221 tgaccttgcg gtacacggcg tcgaactgcg ggtccgacca gccggcctcg ctctgcccgg
     2281 cgccggtgac catggtcttg gaggcgaaga acaccacgga gtcgttggtg ccccagtagt
     2341 tggtgtagag ctgccccttg agccaggtct tctcgtagaa ggcgcccgac tcctgcttga
     2401 cgaccttgat cttgatgccg gcctcgcggg cctggtcggc gaacagcgtc gcggactcgg
     2461 cgagcccggg gacgtcctcg gtggtgacca gctcgtaggt cttggagagg tcgaacttcg
     2521 cttctgcaag cagcttcttg gccttggcga ggtcacggct gcgctggggg atgtccttgg
     2581 cgtaggcggg gtcgccggtg cccaggatgt cgttggcgac ggttccgtag cccgagagga
     2641 cctgtttgac catggcctcg cggtcgacga cgagcttcat ggcctcgcgg accctgacgt
     2701 cggcgaaggg gccgtcggcg gcgcgcatga cgacgggcat cgccatgtcg ttggggcggc
     2761 gcacgagctg gatgtccttg cgcgaggcgg cgctgcgggc cgcgaccgcg ccgacgttgg
     2821 acgcgacgtc gatctggccg cccagcaggg cattggccat ggcctggggg ctctcgaaca
     2881 tggtcacctc gatggcgtcg aggtggaccg gcccgccgtg ccacttgtcg ttgcgcagca
     2941 ggcgggcgtt gccgctgcgg aaccagtcga gcttgaacgg gcccgtgccc ggggccccgg
     3001 cgatctcctt gtcgggggtg tccttcttca ggacgaacgt cgacaggcgg gtgagcaggg
     3061 ggagttcggc gttgggctgg tcggagacga ggacgacggt gtccttgccg ccggcggtga
     3121 tgttctccgc cttgatgccc ggcaaccggg ctgctccggc gggggtgttg cgcagtctgc
     3181 gcagcgacca cacgacgtcg tcggcggtga cgggggagcc gtcgtggaag gcggcgccct
     3241 tggcgatggt gaagcgccag gtcttcaggt cgcccgaagg cgtccagccg gaggcgaggc
     3301 ggccgaccgt gttgtccttg aggcccggtg cggtgagggt gtcgtagacg agcgcgatga
     3361 tcaggtagtc gctttcgttg ccctgggttc cgtgcgggtc gcgggtggtg gcggaggcgc
     3421 ggccgagcgc gcctatgcgg agcgtgccgc ccttccgggg ggtgccggcg gagtccgccg
     3481 gcgaggaggc cgcgtcgttc tcgccgcccc cgcaggcggt gagcagcgcg gccgcgccga
     3541 tgctcccgcc ggcccacagc gcctggcgcc ttgtccagtt cacgtcgtcc ccgttccgct
     3601 gcagttactg gtacttaggt ttgcctaccc tgatattcgc catgatcgca atgttgcgtg
     3661 gacggtgaag cgaaagctga agcaatgtca acctccgctt ccagtacgcg agttgggtgg
     3721 aatcgggagg agtggggcta ctttaaagta aggtttgcct aacctaagtt cggtggtacg
     3781 tttctcggcg tccggtcaag ccaacagccg gatttccgcc acaagttgcc gccccccaca
     3841 ggcagccgtc cgcgcaccgc catgccctgc ggccgcttcc cgggcatgcc cggaaacctc
     3901 tcctccgccc ctgcacacgg aacggatgac cttgccatga gcacgggagc cccacccgta
     3961 cgccggctcg acgccgcctc gtccgccgaa ctccaccgca ccgccggaga gatcctcgcc
     4021 gccttcggca cgtccgccac gtcccccgaa ctgctgcgaa ggatcgccgt gtcggcggcg
     4081 gacctcgccg ggacgatccg cgagcacctg cgccccgtcg acaccgacga cggcctgttc
     4141 gtgctgcgcg gcctgaccgt cgacgacacc cgcatcggcc ccacgcccgc gagctgggcc
     4201 gaggccgggg acagcgcggc cggccacgac atcgtgatgc tgctgctcgc cgccgccatg
     4261 ggcaacccca tcgcctggaa gggccagcag ggcgggcggt tcgtgcacaa catcgttccc
     4321 gcagtcggcc acgagcaggc ccagaccggc gccagcagcg acatcctcct cagcccgcac
     4381 accgaggacg ccttccaccc cggccgcgcc cacctgctga tgctcggctg catgcgcaac
     4441 cacgacaaca tcgccaccac cgcggcgagc attcgcaagg tgcggctgga ggacgccgac
     4501 atcgccacgc tctcccgccc cgaactgccc atcctccccg acgacgccta cttcgaagcg
     4561 cagggcttcg cgggggagcc gccggacgtg cccaccctgt ggcgctccga ggacggcctc
     4621 accctccgct tcgaccccgc ctacaccccc ctggagaagg ccacccccgc ctaccgcgcc
     4681 gcgtacgagc ggctggaggc cgaactcgcc cgcgtctcgg tcgcggtgag cctgagcccc
     4741 ggcgaggtcc tcgtcgtcga caacgatctc gtcgtgcacg gccgcgtccc cttcaaggcc
     4801 cgctacgacg gcaccgaccg ctggctcaag cgcgcctcgg tacgcgtccc cgggcgcggc
     4861 acccggcccc cggccgagga cgccgagcac ggctacggcc aggccgtcac caaggcgtac
     4921 gccgcctgat caccgttcaa cagagagcag tggaaaaccc ggaccggaag acgcccagcc
     4981 ccgcagacga ggagcgagac atgacccgta ccgccgccga cccctgcata tccggcacac
     5041 ccgccgacga caccaccctg cgcgtgctgt ccaccggcga cctcgcaggc atcgacatca
     5101 ccctcgccga cgtcgtcggc acggtcgagg gcgcctaccg caccctggcc gcgggcctct
     5161 cggacaaccc gcgcaagctc accgtcaagc ccgccgacgg gcactcggtc gcgtacgcca
     5221 tgctcggccg cgacggctcc cgcgacgtcg tcgccgtcaa gacctcgtac aagcacggcc
     5281 tggacaaggg gcgccaggag cagcactact acaccaccct caccctctac gacgacgtca
     5341 ccggcctgcc cgtcgcgatg atggactgca gccgcatcgg ctccctgcgc accccggccg
     5401 tctccgccct gctggcccgc gagtgcgccg cccccggggc gcgcagcgcg ctggtcatcg
     5461 gcaccggcac ccagggccgg ctggccctgc cgttcctgct gacgacgctg cccggcctgg
     5521 accggctgat gctcttcggc acccaccccg agggaatcga ggcggtacgg gcgcagctgc
     5581 acgcccactt ccccgaccgc gacgtcgagg tcgtcgccga cgtccgggcc gcggcgggcg
     5641 acgccgacgt cgtcgtcgcc acggccggtg cgcacacccc cgccgccgtc gaggccgagg
     5701 acctggcgcc gggaacgctg gcgatcctgg tcggccacgg cctggacccc tccacgctgc
     5761 accgtgccga ccgcatcgtg gccaccagcg aggcccagat gaacgtcacc ggcaccgaca
     5821 tggcggacgc cgaaggcaaa ctccccgccg tcgacaccga gttccccccg gtcctggcgg
     5881 gcgcggcggc gggccgcacc gcaccgaccg agcggatctt cgcctacaac agcggtctgg
     5941 tcgtcaccga catcgccctc ggccaccgct tcgcccagct cgccctcgca cagggcctgg
     6001 gaacgcaggt gccgctgtgg cggtgaacgg cacgcctccg ccccctccga gcctgcccgc
     6061 gcaccccgac cccgcgacgg acgcggtcct cggcagcggc ctcctccacg agctggccca
     6121 cgccttcggc agccccttcc acttcctgct cccgcaccgc ttcgacgcca acctcgccgc
     6181 gttccgcgcg gcgctggccg acgccggggt ggacgggcgc gtgtactacg cgaagaaggc
     6241 caacaaggcc gccgcatggg tcgaacgctg cgccgccgcg ggcgccggag tggacgtcgc
     6301 gagccccggc gagctccgcg aggccctggg ccacggcgtc cgcggcgaga acatcgtggt
     6361 gaccgggccg gccaagagcg aggaactgct gcgcgtggcc gccctccagg gcgccctgac
     6421 cgcggtcgac tccctcgatg aactcgaccg cctcaccgcg gcgccccggg cgggcggggc
     6481 ccctccgccc cggctgctgc tccgcgtcct gcccccggca cagcccggca gccgcttcgg
     6541 cctggacggg gcggagctcg aggaggccct cacgcactgc gcacgggccg gtgacgccgt
     6601 ccggatggaa ggcttcggct tccacctctc cggctacgcc gtccagccgc gcgccgacct
     6661 cgccggccac ctcgtcgacc tctgcctcaa ggcacgggtc atggggctcc gggccgaccg
     6721 gatcagcatc ggcggcggct tcgccgttga ctactcggcg gccgacgact ggcactcctt
     6781 cctcgcggcg cagcagcccg ggcactacca cgcgcacagg aggttcaccc ccgccgactt
     6841 ctacccgtac cactcgccgg tcgccggggc cgacgccctc cgcgccgtac tggccgccgt
     6901 cccggcgggc ggccgggaca gcctcggcag caggctccgg gagaccggca ccctcctgct
     6961 gatggagccc ggccgcgcgc tgctggaccg ggccggctgc tccgtcttcc gcatccaggg
     7021 cgtcaaggac cgcgacggtt acgcgatcct caccgtcgac ggcacgagcc tgagcctgtc
     7081 cgagcagtgg ttcaacagcg aattcctccc cgaccccgtg ctggtcccca cggccggccg
     7141 ggccgggagg actcggagga ccggggggac cggggggacc ggggtacacc ccgcgtgtgc
     7201 gggcggtgcc acctgcctgg agtcggacct gctcacctgg cgcaagatcc ccttccccgt
     7261 ccgcccctcg gtcggcgacc tgctggtcta ccccaacacg gcgggctacc agatggattc
     7321 gaacgagtcc cccttccacg acctgccgct gccccccaaa gtcgtggtcg acaccaccga
     7381 cgacggcacc gacgacggca ccgacggcac caccgacggc accacgggcg gcggccggcc
     7441 gcgctggcgc ctggaccgcc gacccgcctg ctgacgccct tcccgcgtcc tgacgccctt
     7501 cccgcctcct gaccccaccc cgtctcctga ccccctcccc acctgccaca ggagtccctc
     7561 ccatgaacga ggcactgatg cgccccgccg tggtctcccg catctccgac ctcatcggac
     7621 gcaccccgct gttcgagctg tgccgcaccg acaacggcag ccggctgctc ctcaagctgg
     7681 agatgtacaa ccccaccggc accgccaaga tccgcatggc ccgtcagatg gtcctcgacg
     7741 ccgaggcccg cggcgagctg cgccccggcg gccgcatcat cgagtccacc tccggcaaca
     7801 ccgggctcgg cctcgccgtc gtcgccgccg agcgcggcta cgccttcacc gccgtcgtcg
     7861 accaccacgc ctgttccgac aagctgcgcg ccatgaaggc gctcggcacc gaactcgtct
     7921 acgtggccga cgacggcacc gaggagctgg ccaccgccgc gcgcgaggaa ctcgccgagg
     7981 agatggcccg cggccgggac aacaccgtct tcaccgaaca gcacaacaac cccagcaacg
     8041 gcgtcggcta ccaccccgtc gcccacgagc tccaccaggc cctcggcggc cgcatagacg
     8101 tcctcatcgg cgccgtcggc accggcggct ccctgtgcgg caccgcgagc gagctgcgca
     8161 ggctcgttcc cggcgtgcgg accgtcggcg tcgagcccaa ggggtcgatc gccttcggcg
     8221 gccccgccca cgactactac cagtccggca ccggcacccc cgaaggcgcc gagatcggcg
     8281 cgctggtcga cttcgacctg atcgacgagg gcgtcaaggt cggcgacgtc gaggccttcg
     8341 cgacggcccg cgccgtcgcc cgcaccggcc tcctcatcgg cggctccgcg ggcggcgtcg
     8401 tccacgaggc gctgtcgcgc ctgccgtccc tgccgccggg caccactatc gtcgccctcg
     8461 tcaacgacgg cggggagaag tacatggaca ccgtgttcga cgacgcgtgg atgaacgcca
     8521 ggaacctcac cgatcccgcc ctggagcgcg agatcgacga ggccctcacc aaactccgca
     8581 agggctgatg cccgccatgg acccgaccat cctcctccgc gacggccggg cgctggccgg
     8641 cctcgccgtc cccctcgtcc tcacccagct cgcccaggtg gccctgacca ccaccgacac
     8701 ggtgatgatg ggcctgctga gcacccgcga cctggcggcc ggcggcctgg ccctcgtcat
     8761 cttcaaccag ctccgcacca tgggcgtcgg cctggtcacc tccgtgggca accggatcgc
     8821 ggccgccgcc gcccgcgccg agaccgcgga cggcgacccc gcgcagagcg acgcggaggt
     8881 ccgcaggatc gtccgcgcga gcatggcggt ggccaccctc gccgggctgg ccggggcagt
     8941 cctcatgctc ctcgtcgggc aggccctcac cctgctcggc caggaggccg ccgtcgccga
     9001 ccgcgtacgg acgctgctgc ccgccctcgc ccccggcctg ctgccgtgcc tgtggttcca
     9061 ggcggtccgc cagttcaccg tcggcatgcg ccgcccccag gccctgctgc agatcaccct
     9121 cgcctccgtc gccgtcaacg ccggcctcga ctgggcgctg atccacggca cctggggcct
     9181 gccgaagctg ggcctgaccg gcatcggcgt cgccacctcc gccgtctacc tgctctcctt
     9241 cctcgccctg tacgcctccg cgaggaggga cccggccctc gccccgctgc tcagcctcaa
     9301 cgtgttcgcg gccgaccgca ccaccgtgcg cgagctggtg cgcctgggcg tccccatcgc
     9361 cgccacctac ggatccgagg ccgggttctt ctcggtcacc gccctgatgg ccgggtcctt
     9421 cggcagcgcc gccctggccg cccacacagc cgtcaaccag ctcgtctaca tcgtcttcca
     9481 ggtcgccgtg gggctctccc acgcggcctc catcaacgtc agccgcgaac tcgccctcgg
     9541 ccgcgtccac gccgcactgc gcatcaagaa caccgcgctg gcctgtgccg ccgccgtcat
     9601 ggcagccgtc ggcgccgtct acgtcaccct gcccggcctg gtcctgcgcc cgttcctgga
     9661 cggcggggcc gcgggcgacg acagggccgt gacgatcgcg acgcagctgc tgctcgtcgt
     9721 cgccgtgctc cagttcttcg actgcgcgca gaacatcggc gtcggcctcc tgcgcgggct
     9781 cgacgacacc aggagcggct tccggatcac cctcgtcggc tactgggccg tcggcctccc
     9841 cgccgcctgg ctcttcggct acgcggccgg cctcgacacc ctcggcatct ggctcggcct
     9901 cctcgccggt ctggccacca ccgcggtcct cctcctgcgc cgctacggca gcggcctccg
     9961 cgcccgcgta cgggagcagg aggccgctgc cactgcgtgt ccggggccgc cggccgggcg
    10021 cccgctgcgg aggccgtcag gcgccgacca ggggtgaggg ccgggtgctg cgcagcggcg
    10081 ccgccagttc ggccagggcc ctctccaggt cgtgcaggtg ggcgagggcc ggctcggccg
    10141 gcaggtgctc gggcgctgcc gccgaggcgg ccgccgcgtc gcgcgccttc cccggtgtgg
    10201 tgagcgcctc caccgcggtc tccacgcgcc agcaggcggc ggcgagccgg tcgtcgtggg
    10261 aggcctccgg gtcggcggcc acggacgcca gcccccgcac ttcgcgggcg cagtcgtcga
    10321 ggagcgcgac cacgcggcgg gccttctcct tgcgggcgcg gaaggggttc agcgggtgga
    10381 cgagcggagc gagggagagc cggacccggc cgagcagcag ctccagctcg gtcacccgcg
    10441 gcgcggggtc ggccgtctcc gagccggcca ggcgcgcggc ggcctcggcg gcgcaggcgt
    10501 gcacgcagcg cagggcgcgc tggatccagg cgtcggtggt ggcgtgcgtg gtcaccggca
    10561 gcacgaggag cacggcgagc gccgcaccgg cggctcccac gccggtctgg gccagccgca
    10621 gcgtgagcag gtccgcgtcc aggaccccga ggagcccgta gagcagcccg gccatcaccg
    10681 tcacggcgaa catcatccac gtgtacgaga cggcggcggt gtagaagatg ccgaagacgc
    10741 acaccgcgac gagggccgct gtggccgcgg gcgccccgtg cagggggagg gcgacgacca
    10801 ttccggtggc gatgcccatc accgtgccca ggacccgccg gaagccccgg acgagcgtct
    10861 cgccgcgcga cgcggtgttg acgaagatcc accaggcggt gccgacggcc cagtaccagc
    10921 gctcgtcgga gaccatctgg cccacggcga gcgccaggcc gcaggcgaag gcggtctgga
    10981 aggcctgccg ggtcgtgacg cgcgccagcc cgcgcccggc gaggggcgcc gggcccgcgg
    11041 gcggcggggt gcgccgctcg atgcaccaga acccgaagcg gacggagccc gcggccgcca
    11101 gggacatgat catggccgtg tacaggtgcg gcagctgtgc ggggacggcg tgcaggaact
    11161 gcgtcgcgaa gaacatcatg aagccgaaga tcccgagcgc gttgccccgc gggccccagc
    11221 ggcgggcgta gaccccgcag aagacgacgg cgaggaaggc cgcgtcgcgc accagcggca
    11281 gcccgtgcag cccggccgcc agagcgagca cggggaagcc cacgaccggc agcagcgcgg
    11341 tcgtgttcac ctggcgccgc acggtcgggt cggcgacggt gaacagcgcg agcagcgccg
    11401 tgagcccacc ggtgatggag gcggtcagcg gcaggccgga cagctggacc acggtgaccg
    11461 cgaaggtcac gcccaggacg gcgcggacgg cgatccgcag cctgcccagg cccggatccg
    11521 gtgccatgaa cgccctcttc agcaatgctc ccgccccttc gacgtcctgg ccgagcagcc
    11581 ggcaggaaag ccggcgcgaa tgcgacatga aaaaggcgcc gcggagatcc gcagcgccat
    11641 cgacacccac atcagaccat tacatcgact gctggctcaa cagaggccga tttctctggg
    11701 ccattggccc agtggcggcc tcccgggccg ctccggggga gggccaatgg cacgcacggc
    11761 cctccctcct gccctttcct accgttcgac gtggcctccg cggccggcga gcgcaccggt
    11821 gatccccatc ggcacggcca ggaccaccag cgcgatcagc ccggcggtcc acgccccggt
    11881 caggtcgcgg gcggcgccga aggcggtcgg gcccacggcc gccagcagat agcccacgca
    11941 ctgcgacatc gccgacagca ggcccgcgtc gtgcgtgctg cggacgcaca tcgacatgta
    12001 ggcgatgccc agggagagca cggcccccag accgagcccc agcaagacgg cccacagcac
    12061 cgccgccccg accggcgcgg cgatcaggcc ggcgaaggcg gccatgcaca gcacggtgcc
    12121 gcccaccgcc aggtagctct gccgccggga ccgctgcgcc cacaccggca ccaggagcga
    12181 ggtgaccatg gcggagccca tgcagaccgc cagcagcacc ccggcgccgc cctcggtgta
    12241 gccgtggtcg atgtagaacg acggcagcca ggtggtcgcg gtgtagtaca gcaaggactg
    12301 gaacgcgtag aacagggcga ccgcccaggc cagcctgctg cgccagatcg agccgcccgc
    12361 ctgcgccgcc acccgcggct gctcccgtcc ccggcgcagc cgcggcgccc acaccaccag
    12421 cgccgcgagc gccagcacgc cccagacgga caggccgccg gcccacgaca gcgacagcgc
    12481 gtcgcgcagt ggaacggtcg cggcggccgt gaccgcgccc ccgccgacca gcatggtggt
    12541 gtgcagcccg gacatcagcc cgacctgctg cgggaagtcc cgcttgatca gcgccgtgat
    12601 gaccacgttc gcgacggcca ccgccgtgcc gaccaggaac gtcccggcga acagcgggaa
    12661 cagcgacggg acgatgcgta tcgcggtgcc gcacagcagc accgccagca ctgcgaccag
    12721 ggtgcgttcc atgccccagc ggcgggccag ccggggcgcg agcggagcga agatgccgaa
    12781 gcagatcagc ggcagcgtcg acagcgcgcc ggcgccgccg ttggacaggc cggtgacgtg
    12841 ccggatctcg tccagcagcg gggagaccgc cacgatggcg ggccgcatgt tgatcccgac
    12901 cagcagcacc gccagcgcgt accagagcac gcgacggctc cgcggagtgc cgtgggcggg
    12961 aacggaaccg gggccggaac cgggcccggc cgccgcgccg gcggccgcag cgggcgcacc
    13021 cgccgttccg cggggcgagg aaaccccggt ttccgattca gggggtgggg tcacgaacga
    13081 tccttccggg ggtacgcgca ccgggccgtc gcctccggcc ggcgccaggg gcggagggcg
    13141 ccgggacgag ggcccggtgg gcatgcacgg ctgctgggtc aggcggcggt ggcgaggggc
    13201 acgggtttgc cgtcgccggg ggcgatgccg cggatccccc tggcccgggc cgcccgcagg
    13261 aagcgcccgc gcacgtcgtg ctgctcggtg tagtacggcg ggttgttgaa gaggtcgtag
    13321 tggatcgcgc aggcggtcga cgcctggagg accaccgccg cctcgacggc ctgctccggg
    13381 gtgagcgtgg cgggctggtt ggtcggcgtg aggccctcgc ggcgcgccat caccccggcg
    13441 atgggaagga acgcgacgtc gaaggggccg tagtcgcgcg cgatcgacca ccacatgccg
    13501 tgccagatgg tgtcgccgaa gtggatgacg cgcaggccgg gggcctcgac gatccaggcg
    13561 acctggtcgt cgccgcgcca gtcgtgcg
//
