LOCUS       NZ_LNBE01000003        26686 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces roseifaciens strain MBT76 scaffold_3, whole genome
            shotgun sequence.
ACCESSION   NZ_LNBE01000003
VERSION     NZ_LNBE01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseifaciens
  ORGANISM  Streptomyces roseifaciens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 2630732)
  AUTHORS   Wu,C., Zhu,H., van Wezel,G.P. and Choi,Y.H.
  TITLE     Metabolomics-guided analysis of isocoumarin production by
            Streptomyces species MBT76 and biotransformation of flavonoids and
            phenylpropanoids
  JOURNAL   Metabolomics 12, 90 (2016)
   PUBMED   27073352
REFERENCE   2  (bases 1 to 2630732)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     The complementarity of genome-mining and NMR metabolic-profiling
            facilitates lead-finding
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 2630732)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2015) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.06
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001445655.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 03:28:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,528
            CDSs (total)                      :: 7,450
            Genes (coding)                    :: 7,245
            CDSs (with protein)               :: 7,245
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 205
            CDSs (without protein)            :: 205
            Pseudo Genes (ambiguous residues) :: 0 of 205
            Pseudo Genes (frameshifted)       :: 77 of 205
            Pseudo Genes (incomplete)         :: 168 of 205
            Pseudo Genes (internal stop)      :: 20 of 205
            Pseudo Genes (multiple problems)  :: 56 of 205
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:37:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 717136
            Orig. end                         :: 743822
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LNBE01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26686
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26686
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26686
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16686](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16686
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(129..144)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.52"
                     /tool="antismash"
     misc_feature    989..1003
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            complement(1069..2067)
                     /gene="galE"
                     /locus_tag="AS857_RS09025"
     CDS             complement(1069..2067)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (39-207). E-value:
                     1.3e-11. Score: 36.0. Matches aSDomain:
                     nrpspksdomains_AS857_RS09025_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152793.1"
                     /locus_tag="AS857_RS09025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_058044015.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.4e-19, bitscore:
                     67.3, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 5.1e-14,
                     bitscore: 49.1, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGSHVARAMTQAGERVAVLDDLSAGVAERLPADC
                     VLVRGSVLDRELLDRTFAELGVTGVVHLAAKKQVGESVEKPLLYYRENLHGLTVLLEAA
                     VAAGVHSFVYSSSAAVYGMPDVDLVTEDTPCAPINPYGETKLAGEWLVRATGKAHGLST
                     ACLRYFNVAGAAVPELADTGIFNIIPMMFDRLTRGEAPRIFGDDYATPDGTCVRDYIHI
                     EDLATAHLAAARRLAERTEPGDLTLNVGTGQGVSVREMADLIAEVTGRTEPAPLLEPRR
                     PGDPARVVASNELIAKELGWSPAHDVRSMVASAWEGWCLHHPEARQALPRG"
     aSDomain        complement(1447..1950)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS09025_NAD_binding_4.1"
                     /evalue="1.30E-11"
                     /label="AS857_RS09025_NAD_binding_4.1"
                     /locus_tag="AS857_RS09025"
                     /protein_end="207"
                     /protein_start="39"
                     /score="36.0"
                     /tool="antismash"
                     /translation="RLPADCVLVRGSVLDRELLDRTFAELGVTGVVHLAAKKQVGESVE
                     KPLLYYRENLHGLTVLLEAAVAAGVHSFVYSSSAAVYGMPDVDLVTEDTPCAPINPYGE
                     TKLAGEWLVRATGKAHGLSTACLRYFNVAGAAVPELADTGIFNIIPMMFDRLTRGEAPR
                     IFGDD"
     CDS_motif       complement(1990..2064)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS09025_0001"
                     /evalue="5.10E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="AS857_RS09025"
                     /protein_end="26"
                     /protein_start="1"
                     /score="19.1"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGSHVARAMTQAGER"
     gene            2357..4303
                     /locus_tag="AS857_RS09030"
     CDS             2357..4303
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="AS857_RS09030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_079110189.1"
                     /transl_table=11
                     /translation="MSTAILTGTPPAGSFLEEDLRSLGFDVRVTEDAAGALAAVPATER
                     VALVDPGFVGHVHALRLALTDPRFPAAAVEGALTAQPGARASLTHALRAITGTGPAGQG
                     PASPAAAGEPTDSAEPGRRPSGADGPASARAGEPAGSALSGAGRAPAVGSLPGIVAARL
                     EADGVPVHRPELGVLVAAVPDGDDARAKTLAEVGAVDDEAVRLRNAVKSRDGFFTTFCI
                     SPYSRYLARWCARRGLTPNQVTTASLLTALIAAGCAATGTRGGFVAAGALLLFSFVLDC
                     TDGQLARYSLQYSTLGAWLDATFDRAKEYAFYAGLALGASRGGGHDDVWALALGAMVLM
                     TCRHVVDFAFNEANHDATANTSPTAALSGRLDSVGWTVWVRRMIVLPIGERWALIAVLT
                     ALTTPRTVFYVLLIGCAFAACYTTAGRVLRSLTRKAKRTDRAAQALADLADSGPIAEAA
                     AGSLGRTVPGRAYSAPFWAVLAAASLLLGPLVTGSGGTWRAVLQAAVYAILAGVAVAQP
                     LKGPLDWLVPPIFRGAEYGIILGLAAQSGAPGALPAAFGLVAAVAYHHYDTVYRIRGGT
                     GAPPHLLVRAIGGHEGRVLAVTIAAALWHGRGFTIALTVLAAAIALVVLSESIRFWVSS
                     GAPAVHDETGEPA"
     gene            4300..5037
                     /locus_tag="AS857_RS09035"
     CDS             4300..5037
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010640650.1"
                     /locus_tag="AS857_RS09035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_058042608.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.2e-12, bitscore:
                     45.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGDTTILDLTLANFAEI
                     GLTEVAIIVGYRKEAVYARKEALEAKYGLSLTLIDNDKAEEWNNAYSLWCGRDALKDGV
                     ILANGDTVHPVSVEKTLLAARGNGQKIILALDTVKQLADEEMKVVVDPDKGVQKITKLM
                     DPAEATGEYIGVTLIEGEAAADLADALKVTFERDPDLYYEDGYQELVNRGFKIDVAPIG
                     DVQWVEIDNHDDLAKGRGIACQY"
     gene            5025..6086
                     /locus_tag="AS857_RS09040"
     CDS             5025..6086
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413836.1"
                     /locus_tag="AS857_RS09040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_058042609.1"
                     /sec_met_domain="Fe-ADH (E-value: 6.7e-21, bitscore: 71.6,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRAGALNDLASVLADQRISSSGKLAVAISG
                     GSGAVLRERLAPALPGASWYEVGGGTLDDAIKLADAMKSGHYDAVVGLGGGKIIDCAKY
                     AAARIGLPLVAVATNLSHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPVRF
                     VRSGIGDAISNISAVADWELAARERGEDIDGLAAAMARQAGEAVLRHPGGVGDDGFLQV
                     LAEGLVLTGIAMSVAGDSRPASGACHEINHAFDLLFPKRAASHGEQCGLGAAFAMHLRG
                     AREESALMVEVLRRHGLPVLPQEIGFSAEEFVTAVEYAPQTRPGRYTILEHLALSTDQI
                     RDAYADYAKTVTS"
     gene            6064..6849
                     /locus_tag="AS857_RS09045"
     CDS             6064..6849
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003962488.1"
                     /locus_tag="AS857_RS09045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_079110420.1"
                     /transl_table=11
                     /translation="MPKPSLAELRPVVHPGGLKDRRSGEHWAGRLYMREISLRCTRVLL
                     NTRLTPNQYTGLMILAGIAAGAALVIPGLTGAILGALLIQLYLLLDCVDGELARWRKVT
                     STTGVYLDRVGHYLSEAALLVGFGIRAADVLHEDGAATQWQWAFLGTLAALGAILIKAE
                     TDLVDVARARSGMAAAEDSAATPRSSGMALARRAAAALKFHRLVGGVEASLVILVAGIA
                     DFVHGDLLFTRVAVVLLAAVAVLQTVLHLVSILASSRLR"
     gene            6846..7751
                     /locus_tag="AS857_RS09050"
     CDS             6846..7751
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384775.1"
                     /locus_tag="AS857_RS09050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_058042611.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 4e-12, bitscore:
                     43.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNASSAPSAKVGAVVLTMGNRPAELRALLESVAKQDGDPIEVVVV
                     GNGSPLPPIAVPGLAVRTVELSENVGIPAGRNVGIEAFGPAGREVDVMLFLDDDGLLPG
                     QDTAELCRQAFAADPKLGIISFRIADPDTGVTQRRHVPRLRASDPMRSSRVTTFLGGAN
                     AVRTRVFAEVGGLPDEFFYAHEETDLAWRALDAGWMIDYRSDMVLHHPTTAPSRHAVYH
                     RMVARNRVWLARRNLPAPLVPVYLGVWLLLTLARRPSLPALRAWFGGFKEGWTTPCGPR
                     RPMKWRTVWRLTRLGRPPVI"
     misc_feature    7818..7836
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.82"
                     /tool="antismash"
     gene            7830..8765
                     /locus_tag="AS857_RS09055"
     CDS             7830..8765
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="AS857_RS09055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_058042612.1"
                     /transl_table=11
                     /translation="MSETTHDSAVAMSAPPSPDDGLSAAELAKKYGLAVSGARPSLPEY
                     ARQLWARRHFIVAFSRAKMTAQYSQAKLGQVWQVATPLLNAGVYLLIFGLLMQQSKGMG
                     IATYIPFLVTGVFVFTFTQSSALAGVRSISGNLGLVRALHFPRAALPISFAMQQLQQLL
                     LSMCVLFLFLLGFGHMPDPSWALIVPVLVLQFLFNTGLAMVMARAGSKTPDLAQLLPFI
                     TRTWMYASGVMYNMVEALEKTHAPKWVIDVLSANPAAVYIDLMRWSLIDDHSHIHLPPH
                     VWLLAVGWAVVVGAGGFVYFWKAEEQYGRG"
     gene            8758..9570
                     /locus_tag="AS857_RS09060"
     CDS             8758..9570
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016907919.1"
                     /locus_tag="AS857_RS09060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_173864738.1"
                     /transl_table=11
                     /translation="MAEQNPTADPTGKSAETAARVPTVIAEDVHIVYRVYGGNTGRGSA
                     TAALNRIVKRKPGAGVREVHAVKGVSFTAYRGEAIGLIGSNGSGKSTLLKAIAGLLPTE
                     RGKVYTDGQPSLLGVNAAMMNDLTGEKNVMLGGLAMGMSREQIHERYQGIVDFSGINEK
                     GDFITLPMRTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRSFQKRSEARIRELRKQ
                     AGTVFLVSHNNRSIRDTCDRVLWLEHGQLLMDGPTEEVVRAYEKETAR"
     misc_feature    complement(9690..9700)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     gene            10001..10909
                     /gene="hpnC"
                     /locus_tag="AS857_RS09065"
     CDS             10001..10909
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019985319.1"
                     /locus_tag="AS857_RS09065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene synthase HpnC"
                     /protein_id="WP_058042614.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.6e-33, bitscore:
                     111.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.9e-36,
                     bitscore: 122.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAGTDAHERAVLDKSAHENFPVAPFFLPRTWRDDLMAVYGYARL
                     VDDIGDGDLAPGGRDAQLLGLAGTRADTSEDRLAMLDAFEADLRRVFDRSGTGPRHPLL
                     RRLRPTVRRCGLTPEPFLGLIEANRQDQRVRRYGTYDDLLAYCELSANPVGRLVLGITG
                     TASPERIRRSDAVCTGLQIVEHLQDVTEDLGRDRVYLPAEDMKRFHVTEADLARPTGGA
                     SLRALVAYEGQRAGELLNEGTLLVGSVHGRLKLLLAGFVGGGRAALRAVAAAGHDVLPG
                     PPKPTKLSLLREVGATLRREG"
     gene            10906..11856
                     /gene="hpnD"
                     /locus_tag="AS857_RS09070"
     CDS             10906..11856
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004951784.1"
                     /locus_tag="AS857_RS09070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_058042615.1"
                     /sec_met_domain="phytoene_synt (E-value: 8.3e-59, bitscore:
                     196.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.2e-67,
                     bitscore: 225.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGTVNGSQEASAPVLAAYSYCEAVTGQQAGNFSYGIRLLPTAKR
                     RAMSALYAFSRRVDDIGDGPLDAVDKHRRLEETRELLARIREGRIAEDDTDPVAVALSH
                     AARRFPIPLGGLDELIDGVQMDVRGESYETWDDLAVYCRCVAGAIGRLSLGVFGTVPGA
                     RDAARASEYADTLGLALQLTNILRDVREDAANGRTYLPSDDLAKFGCADGFHSARPPAG
                     ADFTGLVHFEVRRARALFAEGTRLLPMLDRRSGACVAAMAGIYRRLLDRIAEDPEAVLR
                     GRVSLPGREKVYVAVRGLSGLDARSVHRRTAGGRA"
     misc_feature    11873..11889
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.07"
                     /tool="antismash"
     gene            11939..13399
                     /gene="hpnE"
                     /locus_tag="AS857_RS09075"
     CDS             11939..13399
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018520232.1"
                     /locus_tag="AS857_RS09075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_058042616.1"
                     /sec_met_domain="DAO (E-value: 4.9e-09, bitscore: 33.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTTGPGRGPTDGDGAPAARAVVVGGGLAGITAALELADAGVR
                     VTLLEGRPRLGGLAFSFRRGDLTVDNGQHVYLRCCTAYSSFLDRIDALHLAPLQDRLDV
                     PVLDVGHPSGRPRLGRLRRTGLPVPLHLAASLATYPHLSLAERAQVGRAALALRGLDPQ
                     DPALDGTDFASWLRRHGQSARTVEALWDLIGVATLNATAGESSLGLAAMVFKTALLTEP
                     GAADIGWAHVPLGELHDTRARAALDKAGVRTLLRTRATGVGRAADGLWQVDAETGPGTA
                     ERLTAGTVVLALPQRETHALLPDGALDEPGRLLEIGTAPILNLHVVYDRKVLRQPFFTA
                     LGSPVQWVFDRTDSSGLAAGGEDREGCQYLAVSQSAAQDDIDRPVAELRARYLPELERL
                     LPAARGAGVRDFFVTRERTATFAPTPGVGRLRPTARTNTPGLYLAGAWTATGWPATMEG
                     AVRSGVHAAGAALSELGRPHESPLREAV"
     gene            13471..14535
                     /locus_tag="AS857_RS09080"
     CDS             13471..14535
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018088376.1"
                     /locus_tag="AS857_RS09080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_058042617.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.7e-60, bitscore:
                     201.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSAIPAVDTAGVNAMLERGRTLATPVLRAAVDRLAPPMDTVAAY
                     HFGWIDAEGRPAHGDSGKAVRPALALLSAEAAGRAPEVGIPGAVAVELVHNFSLLHDDL
                     MDGDEQRRHRDTVWKVYGPEQAILVGDALFALANEILLELGTVEAGRATRRLTTATRKL
                     IDGQAQDISYEHRERVTVEECLEMEGNKTGALLACAVSIGAVLGGADDHTADTLEAYGY
                     HLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRKKSLPVVAALDAGGSASERLAEILAA
                     DAKLSDAQLADFDEEEFASRAMLIEEAGGREWTSQEARRQHATAIAALDRVDMPAEVRA
                     QLVALADFVVVRKR"
     gene            14653..16686
                     /gene="shc"
                     /locus_tag="AS857_RS09085"
     CDS             14653..16686
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020116600.1"
                     /locus_tag="AS857_RS09085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_058042618.1"
                     /sec_met_domain="T2TS (E-value: 7.8e-150, bitscore: 497.0,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGALPPRAAAATDSTTAQQHTAQGTARPPLQEGEAPG
                     ALAAAERATARAVDHLLSRQDEQGWWKGDLETNVTMDAEDLLLRQFLGVQDEKTTRAAA
                     LHIRSEQRPDGTWATFLGGPGELSTTIEAYVALRLAGDAPDAPHMAAASAWIREQGGIA
                     TSRVFTRIWLALFGWWKWEDLPELPPEIMFLPKWFPLNLYDFGQWARQTIVPLTVVSAK
                     RPVRPAPFALDELHADPARPNPPRPLAPAASWDGVFQRLDKALHHYRRFPLGRLRRLAL
                     DSAARWIIERQENDGCWGGIQPPAVYSIIALHLLGYDLDHPVLREGLKSLDRFAVWRED
                     GSRMIEACQSPVWDTCLATIALADAGVAPDHPALVKAADWMLDEQIHRTGDWAVRRPGL
                     TPGGWAFEFHNDTYPDIDDTAEVVLALKRVRHPEPARVETAVRRAARWNLGMQSKNGAW
                     GAFDADNTSTLPNRLPFCDFGEVVDPPSADVTAHVVEMLAFLGERHDPRTRRGIEWLLA
                     EQEESGAWFGRWGVNYVYGTGSVVPALVAAGIPASHAAVRRAVRWLEGVQNDDGGWGED
                     LRSYRDPEWIGRGASTASQTAWALMALLAAGEREGKAVERGVAWLVETQRADGSWDEPH
                     FTGTGFPWDFSINYHLYRQVFPVTALGRYVHGELFTPDRLEA"
     gene            16686..17336
                     /locus_tag="AS857_RS09090"
     CDS             16686..17336
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004951795.1"
                     /locus_tag="AS857_RS09090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_058042619.1"
                     /transl_table=11
                     /translation="MTNGTGSPGPAPLLVACALGIERLALRGGGPGGAAGPVTVLRTGM
                     GPQAADHAVTRALRDPAMREAAVVATGFCAGLAPGMHPGDLVVADETRDRTGSTECSGV
                     ELLAKELARAVPRRVIHTGPLVGSDHVVRGAERAALHAAGALAVDMESAATLRSAVRAG
                     PRPVAAVRVVVDAPEHELVRIGTLRGGISAFRVLRTVLPAFIEWHRSLLLPRR"
     misc_feature    17316..17318
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17342..18364
                     /gene="hpnH"
                     /locus_tag="AS857_RS09095"
     CDS             17342..18364
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018568734.1"
                     /locus_tag="AS857_RS09095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_058042620.1"
                     /sec_met_domain="PF04055 (E-value: 2.9e-18, bitscore: 63.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 2.9e-09, bitscore: 33.8,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.7e-05, bitscore: 22.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIRVGTYLFEQKLRKREKFPLIVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIHEIVRQLVAKRKYVF
                     LCTNAMLLRKKMDKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAIKEAKRRGF
                     RVTTNSTFFNTDTPQTIVEVLNFLNDELKVDEMMISPAYAYEKAPDQDHFLGVEQTREL
                     FKKAFSGGNRARWRLNHSPLFLDFLEGKVDFSCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEETDWDKYGRGKDPRCDNCMAHCGYEPTAVLATMGSLKESIRAARESVAGNRS
                     "
     misc_feature    17384..17397
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.55"
                     /tool="antismash"
     misc_feature    17385..17398
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.22"
                     /tool="antismash"
     gene            18388..19536
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="AS857_RS09100"
     CDS             18388..19536
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602785.1"
                     /locus_tag="AS857_RS09100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_058044016.1"
                     /transl_table=11
                     /translation="MSLGLPGVPARPLAVRRPSRRIQVGPVAVGGDAPVSVQSMTTTRT
                     SDIGATLQQIAELTASGCQIVRVACPTQDDADALPVIAKKSQIPVIADIHFQPKYVFAA
                     IDAGCAAVRVNPGNIKQFDDKVKEIAKAASDAGTPIRIGVNAGSLDRRLLQKYGKATPE
                     ALVESALWEASLFEEHGFRDIKISVKHNDPVVMVNAYRQLAAQCDYPLHLGVTEAGPAF
                     QGTIKSAVAFGALLSEGIGDTIRVSLSAPPAEEIKVGMQILESLGLRQRRLEIVSCPSC
                     GRAQVDVYKLADQVSAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVK
                     GEVIKTVPESKIVETLIEEALKIADAMTADGALPGAPHVTVA"
     gene            19614..21542
                     /gene="dxs"
                     /locus_tag="AS857_RS09105"
     CDS             19614..21542
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010044657.1"
                     /locus_tag="AS857_RS09105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_058042621.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 7.1e-110,
                     bitscore: 363.6, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.2e-06, bitscore:
                     23.4, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLLENIRSPRDLKTLDAEELTELAEEIRHFLIHAVARTGGHLGP
                     NLGVVELTIALHRSFDSPADRILWDTGHQSYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SEHDVIENSHASTVLGWADGLAKANQVLGRWNRHVVAVIGDGALTGGMAWEALNNIAAA
                     KDRPLIIVVNDNERSYAPTIGGLADHLATLRTTDGYERFLSWGKDAIQGLPAIGKPLYE
                     SLHGAKKGFKDAFAPQGMFEDLGLKYLGPIDGHDVAAVESALRRAKRFHGPVLVHCRTE
                     KGRGYQPALEDDADRFHTVGVIDPLTSRPLAPPAGRSWTSVFGDEMLAIGAERPDVVAI
                     TAAMLHPVGLTKFAEAFPDRVWDVGIAEQHGAVSAAGLATGGLHPVFAVYATFLNRAFD
                     QVLMDVALHKCGVTFVLDRAGVTGTDGPSHNGMWDMSVLQVVPGLRIAAPRDADQLRAQ
                     LREAVEVEDAPTVIRFPKENVGEPVPALAREGGMDVIARPAPGGDEAQVLIVAVGAMAG
                     VCLEAADLLAARGTPCTVVDPRWVKPVDPALPPLAARHRVVAVVEDNSRTGGVGWAVAQ
                     ALRDAGVDVPLRTFGIPEQFLPHAKRGEVLADLGLTPAEIAGRISAALARKEEAARNPA
                     AVKENDA"
     misc_feature    19617..19633
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.49"
                     /tool="antismash"
     gene            21539..22954
                     /locus_tag="AS857_RS09110"
     CDS             21539..22954
                     /NRPS_PKS="Domain: Aminotran_3 (51-373). E-value: 1.2e-90.
                     Score: 295.9. Matches aSDomain:
                     nrpspksdomains_AS857_RS09110_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492039.1"
                     /locus_tag="AS857_RS09110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_058042622.1"
                     /sec_met_domain="Aminotran_3 (E-value: 3.6e-89, bitscore:
                     296.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAETAGAAADGKGFDLTRLLAERGGERYDLHARHLNHQLPRMLH
                     TIGFDKVYERAEGAYFWDADGQDYLDMLAGFGVMGVGRHHPVVRKALHDVLDASLADLT
                     RFDCQPLPGLLAEKLLSYAPHLDRVFFGNSGTEAVETALKFARYATGRPRVLYCSHAFH
                     GLTTGSLSVNGEDGFRDGFAPLLPDTAIPLGDLAALERELARGDVAAFVVEPIQGKGVH
                     EPPAGFLRAAQELLHRHKALLIADEVQTGIGRTGDFFAYQHEEGVEPDLVCVAKALSGG
                     YVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMEDEQIVANARR
                     TGDLLRSRLAALVGKYELLHDVRGRGLMIGIEFGKPSSLGLRSRWAMLQAARKGLFAQM
                     VVVPLLQKHRILTQVSGDHLEVIKLIPPLTIGEREVDRFVDAFTAVMDDAHGGGGLLWD
                     FGRTLVKQAVANR"
     aSDomain        21692..22657
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS09110_Aminotran_3.1"
                     /evalue="1.20E-90"
                     /label="AS857_RS09110_Aminotran_3.1"
                     /locus_tag="AS857_RS09110"
                     /protein_end="373"
                     /protein_start="51"
                     /score="295.9"
                     /tool="antismash"
                     /translation="VYERAEGAYFWDADGQDYLDMLAGFGVMGVGRHHPVVRKALHDVL
                     DASLADLTRFDCQPLPGLLAEKLLSYAPHLDRVFFGNSGTEAVETALKFARYATGRPRV
                     LYCSHAFHGLTTGSLSVNGEDGFRDGFAPLLPDTAIPLGDLAALERELARGDVAAFVVE
                     PIQGKGVHEPPAGFLRAAQELLHRHKALLIADEVQTGIGRTGDFFAYQHEEGVEPDLVC
                     VAKALSGGYVPVGATLGKDWIFKKVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMEDE
                     QIVANARRTGDLLRSRLAALVGKYELLHDVRGRGLMIGIEF"
     gene            complement(22959..23747)
                     /locus_tag="AS857_RS09115"
     CDS             complement(22959..23747)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016571012.1"
                     /locus_tag="AS857_RS09115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_058042623.1"
                     /transl_table=11
                     /translation="MPSTEPELAGVRNFRDLGGLPAAGGRRVRHGVLFRSGHLAHATED
                     DARFLGSLGLHTVFDFRNDADIALDGPDVELTGVRNVNLPLNDPAHGAEFWNMVRARNL
                     GHLRSVLADGRAAERMAETYREVVTGRTAELGHVLRALADDSVPALMHCAAGKDRAGLS
                     VAVTLLALGVGRDVIEADYLESNAPHRRYRMRRAPQSTGPEDREIAELLSPMFEARAAY
                     LHAAFDEMDATWGSADRYLTDGLGLAPAAREHLQSRLLTD"
     gene            23976..24767
                     /locus_tag="AS857_RS09120"
     CDS             23976..24767
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018542873.1"
                     /locus_tag="AS857_RS09120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_058042624.1"
                     /transl_table=11
                     /translation="MADDSNSFSKSAIGSYAAVGDSFTEGVGDPGPDDTFIGWADRLAV
                     LLSDQRAEHDFRYANLAVRGRLLDQIVAEQVPRAKELGPDLVTFCAGGNDILRPGSDPD
                     AVAERYEKAVAELASSVGTVLLCTGFDTRGMPVLRHLRGKIATYTAHVRAIADRHGCPV
                     LDLWSLRSVQDRRAWSDDRLHLSPDGHTRVALRAAQVLGLEVPADPDQAWPDEDHRSPA
                     EVRRDNIHWAREHLVPWIGRRLRGESSGDHVEPKRPDLLPL"
     gene            complement(24816..25301)
                     /locus_tag="AS857_RS09125"
     CDS             complement(24816..25301)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009713863.1"
                     /locus_tag="AS857_RS09125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_079110191.1"
                     /transl_table=11
                     /translation="MSRIAHSYGVVPSHDAPSLGRFGCSMAVRLQDAFHFPARGASVAA
                     ARKRVLAQLREWGIDEVACDDAQLVVSELFTNAVRHTDSANVSCQLRVLGAHLRIEVGD
                     QGRTPTEPRARCSGTDEESGRGLLLVGALSQAWGVRPDDSGRGRVVWADLAAGRLSP"
     misc_feature    complement(25311..25326)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 19.13"
                     /tool="antismash"
     misc_feature    25313..25327
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.72"
                     /tool="antismash"
     misc_feature    complement(25323..25337)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.01"
                     /tool="antismash"
     gene            25417..26283
                     /locus_tag="AS857_RS09130"
     CDS             25417..26283
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981505.1"
                     /locus_tag="AS857_RS09130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_058042626.1"
                     /transl_table=11
                     /translation="MAEARPAGAPTVLRVVLGKRLHDLREKAGLSYEQAGRALDVTHAT
                     VRRMEKAEVGLKLPYVEKLLRVYGVSDAEEVEGFLALAREANRPGWWHRFRDVLPEWFS
                     AFVSLEGEANLIRAYEPHYVPGLLQTERYARAVLRAGMPHAPEADVERAVAVRRERQSL
                     LTREGAPLLWVVIDETVLRRPIGGPDIMREQVARLAEATAMPNVRLQIMPFAAGPHPAM
                     YGPFHIFRFPLPELPDIAYAENLVGASYFDQRDDVSAFLEALDRMCAQAAPAHTTEAIL
                     GGIRKEI"
     gene            26287..26544
                     /locus_tag="AS857_RS09135"
     CDS             26287..26544
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602002.1"
                     /locus_tag="AS857_RS09135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_058042627.1"
                     /transl_table=11
                     /translation="MDRIYNGMPATDLGTEGWSKPWSGGNGGSCVEALRLGDGRIALRQ
                     STDPGGPALIYTRHEMESFINGAKAGAADFLLAGSGAACE"
     misc_feature    26288..26301
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.49"
                     /tool="antismash"
ORIGIN
        1 gtgcagtgct ccacgtcgaa gtgctcgccg aggcagccct gcaggtcgtg cagcattttc
       61 tcgtgcccgg tggagtccag ggccaggtga tcgaccacga cgtgggcgga gagcaccggc
      121 attccggatg tgatcgtcca cacatggagg tcgtgcaggt cctgcacccc gggcagcgcc
      181 atgatgtgtg accggatctc gtccatgtcg acgttccggg gagccgcctc cagcaggacg
      241 tccagcgcct cccgcagcag cttgaccgtg cgcggcacga tcatcaccgc gatcagcagc
      301 gaggcgatcg ggtccgcctg cgtccagccc gtggccatga tcaccagcgc cgagagcacc
      361 acggcgagcg aacccagcgc gtccgagagc acctccagga acgccccgcg cacattgagg
      421 ctctccttct gcccccgcat cagcagcgcc agcgagatcc cgttggcgac cacgcccacg
      481 agaccgaaga cgaccgtctg cccgcccggc acctccgtcg ggttcgccag ccgctcgatc
      541 gcctcgaaga ggatgaagcc gcccacgccg agcagcagca ggcagttcag cagcgccgcg
      601 aggatctcgg cccgggcgta gccgtaggtg cgccggctcg acgccgggcg gttggcgaag
      661 tggatcgcca gcagtgccat cgagacgccc accgcatccg tcgccatgtg acccgcctcg
      721 gcgaacagcg ccagcgaacc ggtcagcgcg ctgccgacga cgtaggccag cagcacggtg
      781 agcgtgatgc ccagggcgat cctgagccgc cccttgtagg ccgcggccgc cgtgccggtc
      841 gtgcccggcg ggggtcctcc gtgcgagtga ccgtgatcgt gtcctgcgcc catgaatgcc
      901 gccttaagaa acgggtgccc gcccggccgg ctcctgccgt ccgggcaccc agtgaactac
      961 gggcgggggg tatcgggcaa cgcggcactg aacaccgttg tcatgtgctc tgacctgcga
     1021 cgatgcccac ctcgccgacc tgcggcgatc acccttgggc ggcccgcgtc agccgcgcgg
     1081 aagagcctgc cgggcctccg ggtggtgcag gcaccagccc tcccacgcgg aagcgaccat
     1141 gctgcgcacg tcgtgcgcgg ggctccagcc gagctccttc gcgatcagct cgttcgacgc
     1201 cacgacacgc gccggatcac ccggacggcg cggctccagc aggggcgccg gctccgtgcg
     1261 gccggtcacc tcggcgatca ggtcggccat ctcccgcacc gagacgccct gccccgtgcc
     1321 cacgttcagc gtcaggtcgc ccggctccgt ccgctcggcc agccggcggg cggcagccag
     1381 gtgcgcggtg gccaggtcct cgatgtggat gtagtcgcgc acgcaggtgc cgtccggcgt
     1441 ggcgtagtcg tcaccgaaga tgcgcggggc ctcgccccgg gtgagccggt cgaacatcat
     1501 cgggatgatg ttgaagatcc cggtgtccgc gagctccggc accgcggcgc ccgccacgtt
     1561 gaagtagcgc aggcacgccg tggacaggcc gtgcgccttg ccggtggccc gcaccagcca
     1621 ctcgccggcc agcttggtct cgccgtacgg gttgatcggc gcgcacggcg tgtcctccgt
     1681 gacgaggtcc acatccggca tgccgtagac ggccgcggag gaggagtaca cgaagctgtg
     1741 caccccggcg gcgaccgccg cctccagcag cacggtcagc ccgtgcaggt tctcccggta
     1801 gtagaggagc ggcttctcca ccgactcccc gacctgcttc ttcgccgcca ggtgcaccac
     1861 gcccgtcacg cccagctccg cgaacgtacg gtcgagcagc tcgcggtcca gcaccgagcc
     1921 ccgcaccagc acgcagtccg cgggcagccg ctcggccacg cccgcggaca ggtcgtccag
     1981 cacggcgacc cgctcgccgg cctgcgtcat cgcccgggcg acgtgcgacc cgatgtatcc
     2041 ggcaccgcct gtgatcagcc atgtcatgac cggcacccta gtgcaggccg ggcggccgtc
     2101 cggtttcgtt cacccgaccc ccgcacccgc cgtgcggtcc ctcacgctcc ggtccggaac
     2161 cacgcgtgcc gcccgctcgt cctgactgtg gcgggccccc tgtcgtcggc ggggtgcacg
     2221 tgcggtgaac ggggccttcc ggtgatccga tagcctctgc cgacgtgccg cccccgccgg
     2281 ggtcgccggc acgactgccg cccgccgcgt cccgcggccc cggggcggcc atgtcagccg
     2341 caaggagtga gttcgtctgt cgaccgccat cctcaccggt acgccgcccg ccggctcctt
     2401 ccttgaggag gacctgcggt ccctcggctt cgacgtccgc gtgacggagg acgccgcagg
     2461 ggcgctggcc gccgtcccgg ccaccgagcg cgtcgctctg gtggaccccg gcttcgtggg
     2521 tcacgtgcac gccctgcggc tggccctgac cgacccccgc ttcccggccg ccgcggtcga
     2581 gggcgcactc accgcccagc cgggcgcgcg tgcgtcactg acgcacgcgc tcagggcgat
     2641 cacgggcacc ggcccggccg gccagggacc cgcttccccc gccgcggcgg gggagcccac
     2701 cgactcggcc gagcccgggc gccgcccgtc cggggcggac gggccggcct ccgcgcgagc
     2761 gggagagcct gccggttccg cgctttccgg cgccggtcgg gccccggccg tcgggagcct
     2821 gcccggcatc gtcgccgccc ggctggaagc cgacggcgtg cccgtgcacc ggcccgagct
     2881 cggcgtgctc gtcgcggccg tgccggacgg ggacgacgcg cgggcgaaga ccctcgccga
     2941 ggtcggggcc gtcgacgacg aggccgtgcg cctgcgcaac gccgtgaagt cccgcgacgg
     3001 gttcttcacc accttctgca tcagcccgta ctcgcgctac ctcgcgcgct ggtgcgcccg
     3061 ccggggcctc acccccaacc aggtcaccac cgcgtccctg ctgaccgcgc tgatcgcggc
     3121 cggctgcgcg gcgaccggca cccgcggcgg cttcgtcgcc gccggcgcgc tgctgctctt
     3181 ctcgttcgtc ctcgactgca ccgacggcca gctcgcccgc tactccctgc agtactccac
     3241 gctcggcgcc tggctcgacg cgaccttcga ccgcgccaag gagtacgcct tctacgcggg
     3301 cctggccctc ggagcgtccc gcggcggcgg ccacgacgac gtgtgggcgc tcgcgctcgg
     3361 cgcgatggtc ctcatgacct gccggcacgt cgtcgacttc gccttcaacg aggcgaacca
     3421 cgacgccacg gccaacacga gcccgacggc cgccctctcc gggcgcctcg acagcgtcgg
     3481 ctggacggtc tgggtccgcc gcatgatcgt gctgcccatc ggcgagcgct gggcgctgat
     3541 cgcggtcctc accgcgctca ccacgccccg caccgtcttc tacgtgctgc tgatcggctg
     3601 cgccttcgcc gcctgctaca ccaccgcggg ccgcgtcctg cgctccctga cccgcaaggc
     3661 gaagcggacc gaccgcgccg cacaggcgct ggcggacctc gccgactccg gcccgatcgc
     3721 cgaggccgcg gcgggcagcc tcggccgcac ggtgcccggc cgcgcctaca gcgcaccctt
     3781 ctgggccgtc ctcgccgccg ccagcctgct cctcggcccg ctggtcaccg gcagcggcgg
     3841 gacctggcgg gccgtcctgc aggccgcggt ctacgcgatc ctcgccggcg tcgccgtcgc
     3901 ccagcccctc aagggccccc tcgactggct ggtcccgccg atcttccgcg gtgcggagta
     3961 cggcatcatc ctggggctgg ccgcgcagtc gggcgccccg ggggcccttc ctgcagcttt
     4021 cggcctggtg gccgcggtcg cctaccatca ctacgacacg gtgtaccgca tccgcggcgg
     4081 caccggcgcg cccccgcacc tgctggtgcg ggcgatcggc ggacacgagg gtcgcgtcct
     4141 ggcggtcacc atcgcggccg ccctgtggca cggccgaggt ttcaccatcg cgctgacggt
     4201 cctcgcggcc gccatcgccc tcgtggtgct cagcgagagc atccgcttct gggtgtcctc
     4261 cggggcaccc gcagtacacg acgaaacagg agaacccgca tgatcggcct cgtgctggcc
     4321 gccggcgccg gacggcgtct gcgtccctac accgacactc tgcccaaggc cctggtgccg
     4381 gtggacggtg acaccaccat cctcgacctc accctggcca acttcgccga gatcggtctg
     4441 accgaggtcg cgatcatcgt gggctaccgc aaggaggccg tgtacgcccg caaggaggcc
     4501 ctggaggcca agtacggcct gagcctcacc ctgatcgaca acgacaaggc cgaggagtgg
     4561 aacaacgcct actccctgtg gtgcggccgg gacgccctca aggacggcgt gatcctcgcc
     4621 aacggtgaca ccgtgcaccc ggtctccgtc gagaagaccc tgctcgccgc ccgcggcaac
     4681 ggccagaaga tcatcctcgc cctcgacacg gtgaagcagc tcgccgacga ggagatgaag
     4741 gtcgtcgtgg accccgacaa gggcgtccag aagatcacca agctgatgga cccggccgag
     4801 gccaccggcg agtacatcgg cgtcaccctg atcgagggcg aggccgccgc cgacctggcc
     4861 gacgccctca aggtcacctt cgagcgcgac cccgacctct actacgagga cggctaccag
     4921 gagctcgtca accgcggctt caagatcgac gtggcgccca tcggcgatgt ccagtgggtc
     4981 gagatcgaca accacgacga cctcgccaag ggccggggga tcgcgtgcca gtactgacga
     5041 ggctcatccc ctcgccggtc gtcgtcgaca tccgggccgg agccctcaac gatctggcga
     5101 gcgtcctcgc cgatcagcgg atctccagct ccggcaagct ggccgtcgcc atcagcggcg
     5161 gctccggggc ggtgctgcgc gagcggctcg ccccggcgct gcccggcgcc tcgtggtacg
     5221 aggtgggcgg cggcacgctg gacgacgcca tcaagctggc cgacgcgatg aagtccggcc
     5281 actacgacgc cgtggtgggc ctcggcggcg gcaagatcat cgactgtgcg aagtacgccg
     5341 ccgcgcgcat cggcctgccc ctggtggccg tcgcgaccaa cctctcgcac gacggcctgt
     5401 gctcgccggt cgcgacgctg gacaacgacg cgggccgcgg ctcgtacggc gtgcccaacc
     5461 ccatcgccgt ggtcatcgac ctcgacgtca tccgtgaggc cccggtccgc ttcgtgcgct
     5521 ccggcatcgg cgacgcgatc tccaacatct ccgctgtggc ggactgggag ctcgccgccc
     5581 gcgagcgcgg cgaggacatc gacggcctgg ccgccgccat ggcccggcag gccggcgagg
     5641 ccgtgctgcg ccaccccggc ggcgtcggcg acgacggctt cctgcaggtg ctcgccgagg
     5701 gcctggtgct caccggcatc gccatgtcgg tggccggcga cagccgcccc gcctccggcg
     5761 cctgccacga gatcaaccac gccttcgacc tgctcttccc caagcgggcg gccagccacg
     5821 gcgagcagtg cggcctcggc gcggccttcg cgatgcacct gcgcggtgcc cgcgaggagt
     5881 ccgcgctgat ggtcgaggtg ctgcgccggc acggcctgcc cgtgctgccg caggagatcg
     5941 gcttcagcgc cgaggagttc gtcacggccg tggagtacgc gccgcagacc cgccccggcc
     6001 gctacacgat cctggagcac ctcgcgctct ccaccgacca gatcagggac gcttacgccg
     6061 actatgccaa aaccgtcact agctgaactc cgcccggtcg tccaccccgg cgggctgaag
     6121 gaccggcgca gcggcgagca ctgggccggg cgcctgtaca tgcgcgagat ctccctgcgc
     6181 tgcacccggg tcctgctgaa caccaggctc acgcccaacc agtacacggg cctgatgatc
     6241 ctggccggca tcgcggcggg cgcggccctg gtgatcccgg gcctcaccgg ggcgatcctc
     6301 ggtgcgctgc tcatccagct gtacctgctg ctggactgcg tggacggcga gctcgcgcgc
     6361 tggcgcaagg tcacctccac gaccggcgtc tacctcgacc gggtgggcca ctacctctcc
     6421 gaggcggccc tcctggtcgg cttcggcatc cgtgcggcgg acgtcctgca cgaggacggc
     6481 gcggccacgc agtggcagtg ggcgttcctg ggcacgctgg ccgcgctcgg cgccatcctg
     6541 atcaaggcgg agacggacct ggtcgacgtg gcccgtgccc gcagcggcat ggcggccgcc
     6601 gaggactccg cggccacgcc gcgctcctcg ggcatggccc tggcccgcag ggccgcggcc
     6661 gcgctgaagt tccaccggct ggtcggcggc gtcgaggcgt cgctggtgat cctggtggcc
     6721 ggcatcgcgg acttcgtcca cggagacctg ctgttcaccc gtgtcgcggt ggtcctgctc
     6781 gccgccgtcg cggtgctgca gactgtgctg cacctcgtgt ccatcctcgc gtcgagcagg
     6841 ctccgatgaa cgcttcctcc gccccttcgg ccaaggtcgg cgcggttgtc ctcaccatgg
     6901 gcaaccgccc cgcggagctg cgcgccctgc tggagtcggt cgccaagcag gacggcgacc
     6961 cgatcgaggt cgtcgtcgtc ggcaacggct ccccgctgcc gccgatcgcc gtccccggcc
     7021 tggccgtgcg caccgtcgag ctgtcggaga acgtcggcat cccggccggg cgcaacgtgg
     7081 gcatcgaggc gttcgggccc gccgggcgcg aggtcgacgt catgctgttc ctggacgacg
     7141 acggcctgct gcccggccag gacaccgccg agctgtgccg gcaggcgttc gccgccgatc
     7201 ccaagctcgg catcatcagc ttccggatcg ccgatcccga cacgggcgtc acccagcgcc
     7261 gccacgtgcc gcggctgcgc gcctccgacc cgatgcgctc ctcgcgggtg accaccttcc
     7321 tcggcggcgc caacgcggtc cgcacccggg tcttcgccga ggtcggcggg ctgccggacg
     7381 agttcttcta cgcgcacgag gagaccgacc tcgcctggcg ggccctcgac gcgggctgga
     7441 tgatcgacta ccgctcggac atggtgctgc accacccgac gacggcgccg agccgccacg
     7501 cggtctacca ccgcatggtc gcccgcaacc gcgtctggct cgcccggcgc aacctccccg
     7561 ccccgctggt cccggtctac ctcggggtgt ggctgctgct caccctggcc cggcggccgt
     7621 ccctgcccgc gctgcgggcc tggttcgggg gcttcaagga gggctggacg actccctgtg
     7681 gtccacggcg ccccatgaag tggcgtaccg tgtggcgcct gacccggctg ggtcggcctc
     7741 ccgtgatctg acaagctctt gtctatgagc atcgggcgcg gaccggggcg agcccccggc
     7801 agcgcacctt gaggacgaaa gtgtcaactg tgagcgagac aacgcacgac agtgcggtcg
     7861 ccatgagtgc cccgccatcg cccgacgacg gactgtccgc cgccgagctg gccaagaagt
     7921 acggtctcgc ggtcagcggg gcccggccga gcctgccgga gtacgcccgg cagctgtggg
     7981 cgcggcggca tttcatcgtc gcgttctccc gggccaagat gacggcccag tacagccagg
     8041 ccaagctggg ccaggtctgg caggtggcga cgccgctgct gaacgccggc gtgtacctgc
     8101 tgatcttcgg tctgctgatg cagcagtcca agggcatggg gatcgccacc tacatcccct
     8161 tcctggtgac cggcgtcttc gtcttcacct tcacccagag ctcggcgctg gccggcgtgc
     8221 ggtccatctc gggcaacctg ggcctggtgc gcgccctgca cttcccgcgg gcggccctgc
     8281 cgatctcctt cgcgatgcag cagctccagc agctgctgct gtcgatgtgc gtgctgttcc
     8341 tcttcctcct cggcttcggg cacatgcccg atccgtcctg ggcgctgatc gtccccgtcc
     8401 tggtgctgca gttcctcttc aacaccggcc tggcgatggt catggcccgg gcgggcagca
     8461 agacgcccga cctggcgcag ctgctgccgt tcatcacgcg gacgtggatg tacgcgtccg
     8521 gcgtgatgta caacatggtc gaggcgctgg agaagaccca cgcgccgaag tgggtcatcg
     8581 acgtgctcag cgccaacccg gccgccgtct acatcgacct gatgcgctgg tccctgatcg
     8641 acgaccacag ccacatccac ctgccgccgc acgtgtggct gctggcggtc ggctgggcgg
     8701 tcgtggtcgg cgccggcggc ttcgtgtact tctggaaggc tgaggagcag tacggccgtg
     8761 gctgaacaga accccaccgc ggaccccacc gggaagtccg cagagaccgc cgcccgggtg
     8821 cccaccgtga tcgcggagga cgtgcacatc gtctaccgcg tctacggcgg caacaccggc
     8881 cggggcagtg cgaccgccgc cctgaaccgc atcgtcaagc gcaagccggg ggccggtgtg
     8941 cgcgaggtgc acgccgtcaa gggagtgagc ttcaccgcct accgcggcga ggcgatcggc
     9001 ctgatcggct ccaacggctc cggcaagtcc accctcctca aggccatcgc cgggctgctg
     9061 cccaccgagc gcggcaaggt ctacaccgac ggccagccct cgctgctggg cgtgaacgcg
     9121 gccatgatga acgacctcac gggcgagaag aacgtgatgc tcggcggtct ggccatgggg
     9181 atgtcgcgcg agcagatcca cgagcgctac cagggcatcg tcgacttctc cgggatcaac
     9241 gagaagggcg acttcatcac gctgcccatg cggacctact cgtccggcat ggcggcccgg
     9301 ctgcggttct ccatcgccgc ggccaaggac cacgacgtgc tgatgatcga cgaggcgctg
     9361 gccaccggtg accgctcgtt ccagaagcgc tccgaggccc gcatccgcga gctgcgcaag
     9421 caggcgggca cggtcttcct cgtcagtcac aacaacaggt cgatccggga cacctgcgac
     9481 cgtgtgctgt ggctcgagca cggacagctg ctcatggacg gcccgaccga ggaagtggtc
     9541 cgggcctacg agaaggagac ggcccgctag gcgccgtacg ggccggcgcg ggccggttcc
     9601 cgcgggccct cgccggtgcg ctccggtgag ggccttgacc tttccgtaac gatcaactgg
     9661 cttattggca gggttgattc gttgctcgcg tggcattgta tggatcaagc acctacccgg
     9721 ccgcgcgtcg gacaggtgtg cggcgtacgc tgtaccgtgc tgatttgcgg cgaagcgtgc
     9781 gataccggtg tatccgcggc tccggagacg gcgtcggata cggcgggaca gtgggtgccg
     9841 aagggggagc agggggcgcc gaagggggtg tctaccctgc ggcgtgtccg aaataggatg
     9901 ttctgggtcg gcagtgtaga acgggagatg tgacggcaat ggctacggat actctccagc
     9961 cccgaggcgt gcacgccgtc cccggtccgg gcagcccgcg gtgacggcgg ggacggacgc
    10021 gcacgagcgc gccgtgctcg acaagtccgc gcacgagaac ttccccgtgg cacccttctt
    10081 cctgccgcgc acctggcggg acgacctcat ggccgtctac gggtacgccc gcctcgtcga
    10141 cgacatcggc gacggcgacc tcgcccccgg cgggcgcgac gcgcagctgc tggggctcgc
    10201 ggggacgcgg gccgacacga gtgaggaccg gctcgcgatg ctggacgcct tcgaggcgga
    10261 cctgcggcgc gtcttcgacc gctccggcac cggcccgcgc cacccgctgc tgcgccgcct
    10321 gcggcccacc gtgcgccggt gcggcctgac cccggagccc ttcctggggc tgatcgaggc
    10381 caaccggcag gaccagcgcg tccgccgcta cggtacgtac gacgatctgc tcgcctactg
    10441 cgagctgtcc gcgaaccccg tcggccgcct cgtcctgggc atcaccggca ccgccagccc
    10501 cgagcggatc cgccgctcgg acgcggtctg caccgggctg cagatcgtgg aacacctgca
    10561 ggacgtcacc gaggacctgg gacgcgaccg cgtctacctc ccggccgagg acatgaagcg
    10621 cttccacgtc accgaggccg acctcgcgcg cccgaccggc ggcgcgtcgt tgcgcgccct
    10681 ggtcgcgtac gaagggcaac gcgccgggga actgctgaat gaaggcaccc tcctggtggg
    10741 tagcgtccac ggcaggttga agctgttgct cgcggggttc gtgggcgggg ggagggccgc
    10801 gctccgcgcg gtcgccgccg caggacacga cgtactgccc ggaccgccca agcccaccaa
    10861 gctcagcctg ctgcgcgagg tgggagcgac actgcgaaga gaggggtgag cgggacagtg
    10921 aacggatcgc aggaagcgtc cgcaccggtg ctcgccgcgt acagctactg cgaggcggtc
    10981 accgggcagc aggcgggcaa cttcagctac ggcatccggc tcctgccgac cgccaagcgg
    11041 cgcgccatgt cggcgctgta cgccttctca cggcgtgtcg acgacatcgg ggacgggccg
    11101 ctggacgcgg tcgacaagca ccgccggctg gaggagacgc gcgagctgct cgcgcggatc
    11161 cgggagggcc ggatcgcgga ggacgacacc gacccggtgg ccgtcgcgct cagccatgcc
    11221 gcgcgccgct tccccatccc gctcggcggg ctggacgaac tcatcgacgg cgttcagatg
    11281 gacgtacgcg gcgagtcgta cgagacctgg gacgacctcg cggtgtactg ccggtgcgtc
    11341 gcgggtgcca tcggccggct ctccctcggc gtgttcggca ccgtgcccgg cgcgcgcgac
    11401 gccgcgcgcg cctcggagta cgccgatacg ctcggcctgg cgctgcagct caccaacatc
    11461 ctgcgcgacg tccgcgagga cgcggccaac ggccgcacct acctgccctc cgacgacctc
    11521 gcgaagttcg gctgcgccga cggcttccac tccgccaggc ccccggccgg cgccgacttc
    11581 accggcctcg tccacttcga ggtccggcgc gcccgcgccc tcttcgccga gggcacccgc
    11641 ctgctgccca tgctggaccg gcgcagcggc gcctgcgtcg ccgccatggc cggcatctac
    11701 cgccggctgc tcgaccggat cgccgaggac cccgaggcgg tcctgcgcgg ccgggtctcc
    11761 ctgcccggcc gggagaaggt ctacgtcgcc gtgcgcggcc tgtccggact cgacgcccgc
    11821 agcgtccacc ggcggaccgc cggggggcgc gcttgatgcc cctgttccgg gccggcaaac
    11881 ggcgcgcaac cctccgccct gcgaaaacgt ccctgagagc agccgaaggg gtgggcacat
    11941 gacagccacg acaaccgggc ccggccgagg ccccaccgac ggggacggcg ccccggccgc
    12001 ccgcgcggtg gtcgtcggcg gcgggctcgc cggcatcacg gccgcgctgg agctcgccga
    12061 cgccggcgtg cgcgtcaccc tcctggaggg gcggccccgg ctcggcggcc tcgccttctc
    12121 cttccgccgc ggcgacctca ccgtcgacaa cggccagcac gtctacctgc gctgctgcac
    12181 cgcctacagc tcgttcctcg accggatcga cgcgctgcac ctcgcacccc tgcaggaccg
    12241 gctcgacgtg cccgtcctcg acgtcggcca cccctccggc aggccccgcc tcggccggct
    12301 gcgccgcacc ggcctgcccg tccccctgca cctggccgcg agcctagcca cgtacccgca
    12361 cctctcgctc gccgagcgcg cccaggtggg ccgcgccgcg ctggccctgc gcggcctcga
    12421 cccgcaggac cccgccctcg acggcacgga cttcgcgagc tggctgcggc gccacggcca
    12481 gtccgcccgc accgtcgagg cgctgtggga cctgatcggc gtggccacgc tcaacgccac
    12541 ggccggcgag tcctcgctcg gcctcgccgc catggtcttc aagaccgcgc tgctcaccga
    12601 gcccggcgcc gccgacatcg gctgggcgca cgtccccctc ggcgagctgc acgacacccg
    12661 cgcccgcgcc gccctcgaca aggccggcgt gcgcaccctg ctgcgcaccc gcgccaccgg
    12721 cgtcggccgc gccgcggacg gcctctggca ggtcgacgcc gagacgggcc ccggcacggc
    12781 cgagcggctc acggccggca cggtcgtgct cgccctgccg cagcgcgaga cccacgccct
    12841 gctgcccgac ggcgccctgg acgagccggg ccggctgctg gagatcggca ccgcccccat
    12901 cctcaacctc cacgtcgtct acgaccgcaa ggtcctgcgg cagccgttct tcaccgcgct
    12961 gggctcgccc gtgcagtggg tcttcgaccg cacggactcc tccggcctcg cggcgggggg
    13021 agaggaccgg gaaggctgcc agtacctggc cgtctcgcag tcggcggcgc aggacgacat
    13081 cgaccggccc gtggccgagc tgcgggcccg ctatcttccc gagctggaac ggctgttgcc
    13141 cgccgcacgc ggcgccggcg tccgggactt cttcgtgacc cgggagcgta cagcgacgtt
    13201 cgcccccacc ccgggcgtcg gccggctgcg gccgaccgcc cgcacgaaca cgcccggcct
    13261 gtacctggcc ggcgcgtgga ccgccaccgg ctggcccgcg accatggagg gcgccgtgcg
    13321 cagcggtgtc cacgccgcgg gtgccgcact ctccgagctc ggccgaccgc acgagagccc
    13381 cttgcgggag gcggtatgac cgaggcgagc catgaagcgt cgcgtgcccg gaccgggccg
    13441 cgcacgagca cgaccaccag aggagagacc gtgacttcgg cgatcccagc tgtcgacact
    13501 gcaggcgtca acgccatgct ggagcgggga cggacgcttg ccacgccggt gctgcgtgcc
    13561 gccgtggacc ggctcgcgcc gcccatggac accgtcgccg cctaccactt cggctggatc
    13621 gacgccgagg gacggccggc gcacggcgac agcggcaagg ccgtccggcc cgcgctcgcc
    13681 ctgctctcgg ccgaggccgc cggacgcgcc ccggaggtgg gcatccccgg cgcggtcgcc
    13741 gtggagctcg tgcacaactt ctccctgctg cacgacgacc tgatggacgg cgacgaacag
    13801 cgccgccacc gcgacaccgt ctggaaggtg tacgggcccg agcaggccat cctcgtcggc
    13861 gacgccctct tcgcgctcgc caacgagatc ctgctggagc tcggcaccgt cgaggccggc
    13921 cgcgccaccc ggcggctgac caccgccacc cgcaagctga tcgacggcca ggcgcaggac
    13981 atctcctacg agcaccgcga gcgggtcacc gtcgaggagt gcctggagat ggagggcaac
    14041 aagaccggcg ccctcctcgc ctgcgcggtc tccatcggcg ccgtcctggg cggcgccgac
    14101 gaccacacgg ccgacaccct ggaggcctac ggctaccacc tcggcctcgc cttccaggcg
    14161 gtggacgacc tgctcggcat ctggggcgac ccggaggcca ccggcaagca gacctggagc
    14221 gacctgcgcc agcgcaagaa gtcgctgccg gtggtcgcgg ccctcgacgc cggcggctcc
    14281 gcctccgagc ggctcgcgga gatcctcgcg gccgacgcca agctcagcga cgcccagctc
    14341 gccgacttcg acgaggaaga attcgccagc cgcgcgatgt tgatcgaaga ggcgggcggc
    14401 cgggagtgga cctcccagga ggcccgccgc cagcacgcga ccgcgatcgc cgccctcgac
    14461 cgagttgaca tgcccgcaga agtccgagcc caactggtgg cgctcgccga cttcgtcgtc
    14521 gtacgaaaga gatgattcct attcacccga tctagcagat cgcggtcgcc ggccggcgcc
    14581 agtgttgcgg cgccggccga cggagccccc aggaaggcag agaaggaagc tcactgcaaa
    14641 aaaggggaaa ccatgacagc gacgaccgac ggaagcaccg gggccctgcc gccccgcgct
    14701 gccgcggcca ccgacagcac cacagcgcaa cagcacactg cacagggcac ggcacggccc
    14761 ccgctccagg agggtgaggc gcccggcgca ctcgccgccg ccgagcgggc cacggcccgc
    14821 gcggtcgatc acctcctctc ccgtcaggac gagcaggggt ggtggaaggg cgacctggag
    14881 accaacgtca ccatggacgc cgaagacctg ctgctccgtc agttcctcgg cgtccaggac
    14941 gagaagacca cccgcgccgc cgcgctccac atccgctccg agcagcgccc ggacggcacc
    15001 tgggccacct tcctcggcgg gcccggcgag ctctccacca ccatcgaggc ctacgtcgcc
    15061 ctgcggctcg ccggggacgc ccccgacgcc ccgcacatgg ccgccgcctc cgcatggatc
    15121 cgcgagcagg gcggcatcgc cacctcccgg gtcttcaccc gcatctggct cgccctcttc
    15181 ggctggtgga agtgggagga cctccccgaa ctgccgcccg agatcatgtt cctgccgaag
    15241 tggttccccc tgaacctcta cgacttcggc cagtgggccc ggcagaccat cgtgcccctg
    15301 accgtcgtct ccgcgaagcg ccccgtgcgc cccgcgccct tcgcgctcga cgagctgcac
    15361 gccgacccgg cccggccgaa cccgccgcgc ccgctcgccc cggccgccag ctgggacggc
    15421 gtcttccagc ggctcgacaa ggccctgcac cactaccgcc ggttcccgct gggccgcctg
    15481 cgccgcctcg cgctcgactc ggccgcccgc tggatcatcg agcgtcagga gaacgacggc
    15541 tgctggggcg gcatccagcc ccccgccgtc tactcgatca tcgccctgca cctcctcggc
    15601 tacgacctgg accaccccgt gctgcgcgag gggctcaagt cgctggaccg tttcgccgtg
    15661 tggcgcgagg acggcagccg catgatcgag gcctgccagt ccccggtgtg ggacacctgc
    15721 ctggccacca tcgccctcgc ggacgccgga gtggcgcccg accacccggc gctggtcaag
    15781 gccgccgact ggatgctgga cgagcagatc caccgcaccg gcgactgggc ggtgcgccgc
    15841 cccggtctga ccccgggcgg ctgggccttc gagttccaca acgacaccta ccccgacatc
    15901 gacgacacgg ccgaggtcgt gctggccctc aagcgggtcc ggcaccccga gcccgcgcgc
    15961 gtggagacgg ccgtccggcg cgccgcccgc tggaacctgg gcatgcagtc gaagaacggc
    16021 gcctggggcg ccttcgacgc ggacaacacc agcacgctgc ccaaccggct gcccttctgc
    16081 gacttcggcg aggtcgtcga cccgccgtcc gccgacgtca ccgcgcacgt cgtcgagatg
    16141 ctcgccttcc tcggcgagcg gcacgacccg cgcacgcggc gcggcatcga gtggctgctg
    16201 gccgaacagg aggagagcgg cgcctggttc ggccgctggg gcgtcaacta cgtctacggc
    16261 accgggtcgg tggtgcccgc cctcgtcgcg gccggcatcc ccgcctcgca cgcggcggtc
    16321 cgccgggccg tgcgctggct ggagggcgtg cagaacgacg acggcggctg gggcgaggac
    16381 ctgcgctcct accgcgaccc cgagtggatc gggcgcggcg cctccaccgc ctcccagacg
    16441 gcctgggccc tgatggccct gctcgccgcc ggcgagcggg agggcaaggc cgtggagcgg
    16501 ggcgtcgcct ggctggtgga gacccagcgc gcggacgggt cctgggacga gccgcacttc
    16561 accggcaccg gattcccctg ggacttctcc atcaactacc acctctaccg gcaggtcttc
    16621 cccgtcacgg ccctcggccg ctacgtgcac ggggagctgt tcacccccga ccgcctggag
    16681 gcgtgatgac gaacggcacg ggcagtcccg gccccgcacc gctgctggtc gcctgcgcgc
    16741 tcggcatcga gcgcctcgcc ctgcgcgggg gcggcccggg cggtgcggcc gggcccgtga
    16801 ccgttctgcg gaccggcatg ggaccgcagg ccgcggacca tgccgtcacc cgcgccctgc
    16861 gcgacccggc gatgcgcgag gccgcggtcg tcgccacggg cttctgcgcc ggcctggccc
    16921 cggggatgca ccccggcgac ctggtcgtcg ccgacgagac ccgggaccgc acgggcagca
    16981 ccgagtgctc gggcgtcgag ctgctcgcca aggagctcgc ccgtgccgtg ccccggcgcg
    17041 tcatccacac cgggcccctc gtcggctcgg accacgtcgt gcgcggcgcg gagcgggccg
    17101 ccctgcacgc cgcgggcgcg ctcgccgtgg acatggagtc cgcggccaca ctccgaagcg
    17161 ccgtgcgcgc gggtccgcgc ccggttgcgg ccgtccgggt ggtcgtggac gctccagagc
    17221 atgaactcgt ccgaatcggg acgttgcgcg gtggaatatc ggctttccgg gttctgcgca
    17281 ccgtcctccc ggcttttatc gaatggcacc gttctttact gctccccagg aggtgagcca
    17341 gatggccatg ccactccgcc agtccatccg ggtgggaacg tacctttttg aacagaagct
    17401 caggaagcgc gagaagttcc cgctgatcgt cgagctggaa ccgcttttcg cctgcaatct
    17461 caagtgcgag gggtgcggga agatccagca ccccgccggg gtgctcaagc agcgcatgcc
    17521 ggtcgcacag gccgtcggcg ccgtgctgga gtccggggcg ccgatggtct ccatcgcggg
    17581 cggcgagcct ctgatgcatc cgcagatcca cgagatcgtg cgccagctgg tggcgaagcg
    17641 gaagtatgtc ttcctttgca ccaacgccat gctcctgcgc aagaagatgg acaagttcac
    17701 cccgtccccc tacttcgcgt tcgcggtgca catcgacggg ctgcgcgagc ggcacgacga
    17761 gtcggtcgcg aaggagggcg tcttcgacga ggcggtggag gccatcaagg aggccaagcg
    17821 gcgcggcttc cgggtcacca ccaactcgac cttcttcaac accgacaccc cgcagaccat
    17881 cgtcgaggtg ctcaacttcc tcaatgacga gctcaaggtc gacgagatga tgatctcgcc
    17941 cgcctacgcc tacgagaagg ctcccgacca ggaccacttc ctgggggtcg agcagacccg
    18001 ggagctcttc aagaaggcct tctccggggg gaaccgggcg cgctggcggc tcaaccacag
    18061 ccccctgttc ctggacttcc tggagggcaa ggtcgacttc tcctgcaccg cctgggcgat
    18121 ccccaactac tccctcttcg gatggcagcg cccctgctat ctgatgagcg acggctacgt
    18181 cccgacgtac cgggagctga tcgaggagac cgactgggac aagtacggcc gcggcaagga
    18241 cccgcgctgc gacaactgca tggcccactg cggatacgag ccgacggccg tcctcgccac
    18301 catggggtcg ctgaaggagt cgatccgcgc ggcccgcgag agcgtcgccg ggaaccggag
    18361 ctgacggccg tggcctccgc gggacccgtg tccctcgggc tccccggcgt gccggcccgg
    18421 ccgctcgcgg tgcgccgccc ctcgcggcgc atccaggtcg ggccggtcgc cgtgggcggt
    18481 gacgcgcccg tttcggtgca gtcgatgacc acgaccagaa cgtcggacat cggcgccacg
    18541 ctccagcaga tcgcggagct gacggcgtcg ggctgccaga tcgtgcgtgt ggcctgcccc
    18601 acgcaggacg acgcggacgc gctccccgtc atcgcgaaga agtcgcagat ccctgtcatc
    18661 gcggacatcc acttccagcc gaagtacgtc ttcgccgcga tcgacgccgg ctgcgccgcg
    18721 gtccgtgtga acccgggcaa catcaagcag ttcgacgaca aggtcaagga gatcgccaag
    18781 gcggcctccg acgcgggcac cccgatccgt atcggcgtga acgcggggtc gctggaccgc
    18841 cgcctgctgc agaagtacgg caaggcgacg cccgaggcgc tggtggagtc ggcgctgtgg
    18901 gaggcctcgc tcttcgagga gcacggtttc cgcgacatca agatctcggt caagcacaac
    18961 gacccggtgg tgatggtcaa tgcgtaccgt cagctggcgg cgcagtgcga ctacccgctg
    19021 cacctgggcg tgaccgaggc cggcccggcg ttccagggca cgatcaagtc cgcggtggcg
    19081 ttcggtgcgc tgctgtcgga gggcatcggc gacaccatcc gcgtctcgct gtcggcgccg
    19141 ccggcggagg agatcaaggt cggcatgcag atcctggagt ccctgggcct gcgccagcgc
    19201 cgcctggaga tcgtctcctg cccgtcctgc ggtcgtgcgc aggtggacgt gtacaagctc
    19261 gccgaccagg tcagcgccgg cctggagggc atggaggtgc cgctgcgcgt cgcggtgatg
    19321 ggctgcgtcg tcaacggtcc gggtgaggcc cgtgaggccg acctgggtgt cgcctcgggc
    19381 aacggcaagg ggcagatctt cgtcaagggc gaggtcatca agaccgtgcc ggagtcgaag
    19441 atcgtggaga ccctcatcga ggaagcactg aagatcgccg atgccatgac ggcggacggg
    19501 gccctccccg gggcgccgca cgtcaccgtg gcctgagacc ggcgacccac caccgtagga
    19561 acagcgaccg tgcggccgcc cggcccaggc cgcaagacga ggagggggcc cgcgtgtcgt
    19621 tgctggagaa catccgcagt ccgcgcgacc tgaagaccct ggacgccgag gagctgaccg
    19681 aactggcgga ggagatccgc cacttcctca tccacgccgt cgccaggacc ggcggccacc
    19741 tcggccccaa cctgggcgtg gtggagctca ccatcgccct gcaccgctcc ttcgactcac
    19801 cggccgaccg catcctgtgg gacaccggcc accagtcgta cgtgcacaag ctgctcaccg
    19861 gccgccagga cttctccaag ctgcgcggca agggcggcct gtccggctac ccctcgcgcg
    19921 aggagtccga gcacgacgtc atcgagaaca gccacgcctc gaccgtcctc ggctgggccg
    19981 acggcctcgc caaggccaac caggtcctcg gccgctggaa ccgccacgtc gtcgccgtca
    20041 tcggcgacgg ggccctgacc ggcggaatgg cctgggaggc gctcaacaac atagccgccg
    20101 ccaaggaccg cccgctgatc atcgtcgtca acgacaacga gcgcagctac gcccccacca
    20161 tcggcggcct cgcggaccac ctcgccacgc tccgcacgac cgacggctac gaacgcttcc
    20221 tgtcctgggg caaggacgcg atccagggcc tgcccgccat cggcaagccc ctctacgagt
    20281 ccctgcacgg cgcgaagaag ggcttcaagg acgcgttcgc cccgcagggc atgttcgagg
    20341 acctgggcct gaagtacctc ggcccgatag acgggcacga cgtcgccgcc gtcgagtccg
    20401 cgctgcgccg ggccaagcgc ttccacggcc ccgtcctcgt ccactgccgc acggagaagg
    20461 gccgcggcta ccagcccgcc ctggaggacg acgccgaccg cttccacacc gtcggcgtga
    20521 tcgacccgct cacctcccgg ccgctggccc cgccggccgg ccgctcctgg acctcggtct
    20581 tcggcgacga gatgctcgcc atcggggccg agcggcccga cgtggtcgcc atcaccgctg
    20641 ccatgctcca ccccgtgggc ctgacgaagt tcgccgaggc cttccccgac cgcgtctggg
    20701 acgtcggcat cgccgagcag cacggcgcgg tgtccgcggc cggcctggcc accggcgggc
    20761 tgcacccggt cttcgccgtc tacgccacgt tcctcaaccg cgccttcgac caggtgctga
    20821 tggacgtcgc cctgcacaag tgcggcgtga ccttcgtcct ggaccgggcg ggcgtcaccg
    20881 gcaccgacgg gcccagccac aacggcatgt gggacatgtc ggtcctgcag gtcgtccccg
    20941 gtctgcggat cgccgccccg cgcgacgccg accagctgcg cgcccagctg cgcgaggccg
    21001 tcgaggtcga ggacgccccc accgtgatcc gcttcccgaa ggagaacgtc ggcgagcccg
    21061 tcccggccct ggcccgcgaa ggcggcatgg acgtcatcgc ccgccccgca cccggcgggg
    21121 acgaggcgca ggtcctgatc gtcgcggtcg gcgccatggc cggcgtgtgc ctggaggccg
    21181 ccgacctcct ggccgcccgc ggcactccct gcaccgtcgt cgacccgcgc tgggtcaagc
    21241 ccgtcgaccc cgcgctgccc ccgctcgccg cacgccaccg cgtcgtcgcg gtcgtcgagg
    21301 acaacagccg taccggcggc gtcggctggg ccgtcgcgca ggcgctgcgc gacgccggcg
    21361 tcgacgtgcc gctgcgcacc ttcggcatcc ccgagcagtt cctgccgcac gccaagcgcg
    21421 gcgaggtcct ggcggacctc gggctcaccc ccgccgagat cgccggccgg atcagcgccg
    21481 ccctggcccg caaggaagaa gccgcgagga accccgcggc cgtgaaggag aacgacgcat
    21541 gacagccgag acagccggtg ccgccgccga cggcaagggc ttcgacctca cccggctcct
    21601 cgcggagcgc ggcggcgagc ggtacgacct gcacgcccgg cacctcaacc accagttgcc
    21661 gcgcatgctg cacaccatcg gcttcgacaa ggtctacgag cgggccgagg gcgcctactt
    21721 ctgggacgcc gacgggcagg actacctcga catgctcgcc ggcttcggcg tgatgggcgt
    21781 cggccggcac caccccgtcg tccgcaaggc gctgcacgac gtcctcgacg cctcgctcgc
    21841 cgacctcacc cgcttcgact gccagccgct gcccggcctc ctcgccgaga agctgctgtc
    21901 gtacgcgccg cacctggacc gggtgttctt cggcaacagc ggcaccgagg cggtggagac
    21961 ggccctgaag ttcgcgcggt acgcgacggg caggccgcgg gtcctctact gctcccacgc
    22021 cttccacggc ctgaccaccg gctcgctctc cgtcaacggc gaggacggct tccgggacgg
    22081 cttcgcgccc ctgctgcccg acacggcgat cccgctcggc gacctcgccg ccctggagcg
    22141 ggagctcgcc cgcggcgacg tggcggcgtt cgtcgtcgaa ccgatccagg gcaagggcgt
    22201 ccacgagccg cccgccggct tcctgcgcgc cgcgcaggag ctgctccacc ggcacaaggc
    22261 gctgctcatc gccgacgagg tgcagaccgg cattggccgc accggcgact tcttcgccta
    22321 ccagcacgag gagggcgtcg agccggacct ggtctgcgtg gccaaggcgc tctcgggcgg
    22381 ctacgtgccc gtcggcgcca ccctcggcaa ggactggatc ttcaagaagg tctactcctc
    22441 catggaccgg gtcctggtgc actccgcgag cttcggctcc aacgcgcagg cgatggccgc
    22501 cgggctcgcg gtgctctccg tgatggagga cgagcagatc gtcgccaacg cccggcgcac
    22561 gggcgacctg ctgcgcagcc ggctcgccgc gctcgtcggc aagtacgagc tgctgcacga
    22621 cgtccgcggc cggggcctga tgatcggcat cgagttcggc aagccgtcct cgctggggct
    22681 gcgcagccgc tgggccatgc tccaggcggc ccgcaagggc ctcttcgcgc agatggtcgt
    22741 ggtgccgctg ctgcagaagc accgcatcct cacccaggtc tccggcgacc acctggaggt
    22801 gatcaagctg atcccgccgc tgaccatcgg ggagcgcgag gtggaccgct tcgtggacgc
    22861 cttcacggcg gtgatggacg acgcccacgg cggaggcggt ctgctgtggg acttcgggcg
    22921 gacgctggtg aagcaggcgg tggcgaaccg ctgagccctc agtccgtgag cagcctgctc
    22981 tgcaggtgct cacgggccgc cggggcgagc cccagcccgt ccgtcaggta gcggtcggcc
    23041 gagccccacg tcgcgtccat ctcgtcgaac gcggcgtgca ggtacgcggc gcgcgcctcg
    23101 aacatcggcg acagcagctc cgcgatctcc cggtcctcgg gccccgtcga ctgcggcgcg
    23161 cgccgcatcc ggtagcgccg gtgcggcgcg ttcgactcca ggtagtcggc ctcgatcacg
    23221 tcgcggccga cgccgagggc gagcagggtg accgcgacgg acagcccggc gcggtccttc
    23281 ccggccgcgc agtgcatcag cgccggcacg ctgtcgtcgg cgagggcgcg caggacgtgg
    23341 ccgagctcgg ccgtgcggcc cgtgacgacc tcccggtacg tctcggccat ccgctccgcg
    23401 gctctgccgt cggccagcac gctccgcagg tgcccgaggt tgcgggcgcg caccatgttc
    23461 cagaactcgg cgccgtgggc cgggtcgttg agggggaggt tgacgttccg gacgccggtg
    23521 agctcgacgt ccggcccgtc gagcgcgatg tcggcgtcgt tgcggaagtc gaagaccgtg
    23581 tgcaggccga gcgagccgag gaagcgcgcg tcgtcctcgg tggcgtgggc gaggtgcccg
    23641 ctgcggaaga ggacgccgtg ccgtacccgc cgtccgccgg cggccggcag accgccgagg
    23701 tcgcggaagt tgcgcacccc cgccagctcg ggctcggtgg acggcatatg cggcgtctgc
    23761 gtcacgggcg ctcccagggc tgggccgccg gcgctcctcg ccggcgacgc ggttcaacga
    23821 ccttacgaca ccggttgtac gggcaaccgc cccgctgtgg tagccgcgcc gacgtattcc
    23881 gcgtacacgg acttatcggg gtgggataca tcacggctcg tcaacccctg gttacggtgg
    23941 cgtaggtcac tcctcgcgag gaaagatgta ccaacgtggc agacgattcg aattcattca
    24001 gcaagagcgc gatcgggtcg tacgcagccg tcggggacag cttcaccgaa ggcgtcggcg
    24061 acccgggtcc ggacgacacc ttcatcggct gggccgaccg actggccgta ctcctctccg
    24121 accagcgcgc cgagcacgac ttccgctacg ccaacctcgc cgtgcgcggc cgtctcctgg
    24181 accagatcgt cgcggagcag gtgccccggg cgaaggagct cggcccggac ctcgtgacgt
    24241 tctgcgcggg cggcaacgac atcctgcgcc cgggcagcga cccggacgcc gtggccgagc
    24301 gctacgagaa ggccgtcgcc gagctggcct cctccgtggg caccgtcctg ctgtgcaccg
    24361 gcttcgacac ccgcgggatg cccgtgctgc ggcacctgcg cggcaagatc gcgacgtaca
    24421 cggcccacgt ccgggccatc gcggaccggc acggctgccc ggtcctggac ctgtggtcgc
    24481 tgcgctcggt gcaggaccgc agggcgtgga gcgacgaccg gctccacctc tcgcccgacg
    24541 ggcacacgcg ggtcgccctg cgggccgccc aggtgctcgg cctggaggtg ccggccgacc
    24601 cggaccaggc ctggccggac gaggaccacc gctcgcccgc cgaggtgcgg cgcgacaaca
    24661 tccactgggc gcgcgagcac ctggtgccgt ggatcggccg ccggctgcgc ggcgagtcct
    24721 cgggggacca cgtggagccc aagcggccgg atctcctgcc gctgtagcgc ttttgcagtg
    24781 ccttttgcgg tgccttcagg ccgccgggat gcctttcagg gggagagccg cccggcggcg
    24841 aggtcggccc agacgacacg gccccggccg ctgtcgtcgg gccggacccc ccatgcctgc
    24901 gacagcgcgc ccacgagcag caggccccgg ccgctctcct cgtccgtccc gctgcaccgg
    24961 gcccgtggct ccgtcggggt gcggccctgg tcgcccacct ctatgcgcag gtgcgcaccg
    25021 agcaccctca gctgacagct gacgttcgcg ctgtccgtgt gccggaccgc gttggtgaag
    25081 agctccgaca ccaccaactg ggcgtcgtcg cacgccactt cgtcgatgcc ccactcccgc
    25141 agttgtgcga ggacccgttt tcgcgcggcg gccaccgagg cgccacgagc cgggaagtgg
    25201 aaggcgtcct gcagacgtac ggccatggaa cagccgaagc gcccgagcga aggtgcgtca
    25261 tgggagggga ccacgccgta actatgtgcg atacggctca tgtgtggcaa ggttcaatct
    25321 gtaaattgca gaatcgtcag atcagtctgt cggctccggg gggtgcgtga cagactgcgg
    25381 gcatatgaca accggtgggc atggaggggg agaacagtgg cggaagcgcg tccggcgggc
    25441 gcaccgaccg tcctgcgggt cgtgctcggc aaacggctgc acgacctgag ggagaaggcc
    25501 ggtctctcct acgagcaggc gggccgcgcc ctcgacgtca cccacgccac cgtccgcagg
    25561 atggagaagg ccgaagtcgg cctgaagctc ccctacgtgg agaagctcct gcgcgtctac
    25621 ggcgtgagcg acgccgagga ggtggagggc ttcctcgccc tcgcccgcga ggccaaccgc
    25681 cccggctggt ggcaccgctt ccgggacgtc ctgcccgagt ggttcagcgc gttcgtcagc
    25741 ctggagggcg aggccaacct catccgggcc tacgaaccgc actacgtccc gggcctgctg
    25801 cagaccgagc gctacgcacg cgccgtgctc cgcgccggca tgccgcacgc cccggaggcg
    25861 gacgtcgagc gggcggtcgc cgtccgccgg gagcgccagt cgctgctgac ccgcgagggc
    25921 gcgccgctgc tgtgggtggt gatcgacgag acggtgctcc gccggcccat cggcgggccg
    25981 gacatcatgc gcgagcaggt cgcccgcctc gccgaggcca ccgccatgcc caacgtacgg
    26041 ctgcagatca tgccgttcgc cgccgggccg cacccggcga tgtacggacc gttccacatc
    26101 ttccggttcc cgctcccgga gctgccggac atcgcctacg ccgaaaacct cgtcggcgcc
    26161 tcgtacttcg accagcgcga cgacgtctcg gccttcctgg aggcgctgga ccgcatgtgc
    26221 gcgcaggccg cgccggcaca caccaccgag gcaatcctgg gtgggattcg taaggagatc
    26281 tgaaccatgg atcgcatcta caacggcatg cccgccaccg acctcggcac cgaggggtgg
    26341 agcaagccgt ggagcggcgg caacgggggc tcgtgcgtcg aggcgctgcg gctgggcgac
    26401 ggccggatcg ccctgcgcca gtccaccgac cccgggggcc ccgcgctgat ctacacgcgt
    26461 cacgagatgg agagcttcat caacggggcc aaggcgggcg cggcggactt cctgctcgcc
    26521 ggctccggcg ccgcctgcga atgaccccgc agggcacgtg cacggcaccg ccgggcggcc
    26581 cgggccgccc gtgcgccgcg gcgtcacccc ctaccgcgca accaaccgaa cggagcaccg
    26641 catgagccag cagggcttcg cggccgagga catcgacacc agccgg
//
