LOCUS       NZ_LNBE01000003        48917 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces roseifaciens strain MBT76 scaffold_3, whole genome
            shotgun sequence.
ACCESSION   NZ_LNBE01000003
VERSION     NZ_LNBE01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseifaciens
  ORGANISM  Streptomyces roseifaciens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 2630732)
  AUTHORS   Wu,C., Zhu,H., van Wezel,G.P. and Choi,Y.H.
  TITLE     Metabolomics-guided analysis of isocoumarin production by
            Streptomyces species MBT76 and biotransformation of flavonoids and
            phenylpropanoids
  JOURNAL   Metabolomics 12, 90 (2016)
   PUBMED   27073352
REFERENCE   2  (bases 1 to 2630732)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     The complementarity of genome-mining and NMR metabolic-profiling
            facilitates lead-finding
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 2630732)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2015) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.06
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001445655.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 03:28:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,528
            CDSs (total)                      :: 7,450
            Genes (coding)                    :: 7,245
            CDSs (with protein)               :: 7,245
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 205
            CDSs (without protein)            :: 205
            Pseudo Genes (ambiguous residues) :: 0 of 205
            Pseudo Genes (frameshifted)       :: 77 of 205
            Pseudo Genes (incomplete)         :: 168 of 205
            Pseudo Genes (internal stop)      :: 20 of 205
            Pseudo Genes (multiple problems)  :: 56 of 205
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:37:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 545562
            Orig. end                         :: 594479
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LNBE01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..48917
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRP-metallophore"
                     /product="NRPS"
                     /region_number="3"
                     /rules="(VibH_like or Cy_tandem or (cds(Condensation and
                     AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or
                     TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or
                     (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or
                     PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like))
                     or Lys_monoox or VbsL)))"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /tool="antismash"
     cand_cluster    1..48917
                     /SMILES="NC(CO)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /kind="chemical_hybrid"
                     /product="NRP-metallophore"
                     /product="NRPS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..48917
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:28917](+)"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..28917
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="30000"
                     /detection_rule="(VibH_like or Cy_tandem or
                     (cds(Condensation and AMP-binding) and ((IBH_Asp and not
                     SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or
                     CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD
                     and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox
                     and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))"
                     /neighbourhood="20000"
                     /product="NRP-metallophore"
                     /protocluster_number="1"
     misc_feature    454..468
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.57"
                     /tool="antismash"
     misc_feature    465..480
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.57"
                     /tool="antismash"
     misc_feature    complement(469..482)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.2"
                     /tool="antismash"
     gene            complement(481..1320)
                     /locus_tag="AS857_RS08375"
     CDS             complement(481..1320)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1215: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004945463.1"
                     /locus_tag="AS857_RS08375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_058042495.1"
                     /transl_table=11
                     /translation="MPQPAKAVRTPRTAGEVPRETRDPHPDTESAGSRRAAAQRLTMRR
                     KLAAAAMELFATKGYEATTVDEIAAAAGVARRTFFRHFRSKEEAIFPDHDDTLVRAAGV
                     LDAAPPHENPLDTVCRGIKEVMRMYAASPAVSVERYRLTREVPALREREIASVARYERL
                     FTRYLLGHFDESAHHVGDDDPLLAEVAASAVVTAHNHVLRRWLRGGGQGDVETQLDHAF
                     AIVRETFGTGIGAGRARAEDGPAASARTEGEVLVTVARTDAPLGEVMRAIEKALKTK"
     gene            complement(1421..>2275)
                     /locus_tag="AS857_RS08380"
                     /pseudo=""
     CDS             complement(1421..>2275)
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /GO_process="GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1095: 3-hydroxybutyryl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004945461.1"
                     /locus_tag="AS857_RS08380"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="3-hydroxyacyl-CoA dehydrogenase NAD-binding
                     domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="PLRTVAVVGLGTMGTGIAEVLVRAGREVVGIDVSEAAAAHAVRAL
                     ETATARAVRRERITEDERRAALARFRTATDLQAAAGADLVIEVVPEDYAVKHEVFTALD
                     AIVRPETILATGTNALSVTRLAADSARPERVLGMHFFNPAPAMKLVEVVRTVLTADDVH
                     ATVRAVCAKVRKHAVDCGDRAGFIVNALLFPYLNNAVKMVQEHYASPDDIDAAMKLGGG
                     YPMGPFELLDVVGLDVSLAIEKVLHREFRDPGLAPAPLLEHLVAAGCLGRKTGRGFREY
                     AKA"
     misc_feature    complement(2605..2622)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.16"
                     /tool="antismash"
     gene            2690..3319
                     /locus_tag="AS857_RS08385"
     CDS             2690..3319
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004945459.1"
                     /locus_tag="AS857_RS08385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="WP_245699703.1"
                     /transl_table=11
                     /translation="MTGAERAEEEFRALVKRVRAELGTSAEFSEFERLLALVRSREGGP
                     PARRARRDELAGMLVAPEQPLWAREIAAFVLGAEGDRRAFETLILLLNYREPVRCATAA
                     FVLARLGDPRTARAAAALATNPLRTAYALHPVRLLTELRAPESVPALLATLERLLAARD
                     HCWPIARACVEGLGALGDRRAEDALVAAREHDRLRAAAQEALERLM"
     gene            complement(3350..4387)
                     /locus_tag="AS857_RS08390"
     CDS             complement(3350..4387)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018837083.1"
                     /locus_tag="AS857_RS08390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rv2578c family radical SAM protein"
                     /protein_id="WP_058042497.1"
                     /transl_table=11
                     /translation="MRWSNLGGDGADDGPGALFGTDVVTRTLDTPEFRGITFHEVRAKT
                     IVNRVPGASRMPFEWTVNPYRGCTHACVYCFARKTHGYLDLDTGLGFDTQIVVKVNAPE
                     ALRRELAAPRWRGEHIAMGTNVDCYQRAEGRYRLMPGIISALRERANPFSVLTKGTLIL
                     RDLELLREAAAVTDVGVSMSVGFLDHELWRTVEPGTPSPARRLDAVRTLTGHGIPCGVL
                     MAPVIPFLGDSPEQLRATVRAVAASGATSVTPLVLHLRPGAREWFTAWLARHHPHLVRR
                     YETMYADGAYAPKWYQRRITRQVHEYATEFGIGPTGPGRHRRIPAAPPQDPGPTPPQAT
                     QLTLL"
     misc_feature    complement(4412..4425)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.45"
                     /tool="antismash"
     misc_feature    complement(4439..4453)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.05"
                     /tool="antismash"
     misc_feature    4439..4454
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.96"
                     /tool="antismash"
     misc_feature    4440..4453
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: strong, score: 23.52"
                     /tool="antismash"
     misc_feature    4527..4542
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.06"
                     /tool="antismash"
     gene            4561..5004
                     /locus_tag="AS857_RS08395"
     CDS             4561..5004
                     /NRPS_PKS="Domain: Polyketide_cyc2 (3-146). E-value: 7e-23.
                     Score: 73.5. Matches aSDomain:
                     nrpspksdomains_AS857_RS08395_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010038765.1"
                     /locus_tag="AS857_RS08395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC family protein"
                     /protein_id="WP_058042498.1"
                     /transl_table=11
                     /translation="MGQVEATTERIIAADPEEVFDALADYTGTRAKLLPEHFSEYEVRE
                     GGDGEGTLVHWKLQATSKRVRDCLLEVAEPTTGQLVEKDRNSSMVTTWTVTPAGEGRAR
                     VVVSTVWNGAGGIGGFFERTFAPKGLGRIYDAVLDKLAAETEK"
     aSDomain        4570..4998
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08395_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="7.00E-23"
                     /label="AS857_RS08395_Polyketide_cyc2.1"
                     /locus_tag="AS857_RS08395"
                     /protein_end="146"
                     /protein_start="3"
                     /score="73.5"
                     /tool="antismash"
                     /translation="VEATTERIIAADPEEVFDALADYTGTRAKLLPEHFSEYEVREGGD
                     GEGTLVHWKLQATSKRVRDCLLEVAEPTTGQLVEKDRNSSMVTTWTVTPAGEGRARVVV
                     STVWNGAGGIGGFFERTFAPKGLGRIYDAVLDKLAAETE"
     protocluster    4823..48917
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[24822:28917](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      24823..28917
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="2"
     misc_feature    complement(5175..5187)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.22"
                     /tool="antismash"
     gene            5229..7613
                     /locus_tag="AS857_RS08400"
     CDS             5229..7613
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019071307.1"
                     /locus_tag="AS857_RS08400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_058042499.1"
                     /transl_table=11
                     /translation="MGGTTLVQSDGPPVPVLLAPEAAPAPPAPPEPPTVRGRLGVVLAG
                     LLLALFLAAIDQTVVATALPAIAGDLHGAGRATWIITAYLLGSAVAVPVHGRLGETAGR
                     KGVFAFAVVLLVAGSALAARAQTMDQLLAFRALQGIGGGGVLAAVHAIIADLTPARERR
                     RRLGAAAAVLALASLAGPPLGGLLTDHASWRWCFHLNVPLGLLALLAVTFGLRLPRPAH
                     RARFDTLGALLLVAFSVCAVLLADRAGTAPAWHARVVLGLAAATLGTALLFIVVEHLAA
                     DPLVPPRLLRDRTFLVCAALGAGTGAALFGAVGCLPTFLQMADGAGAVRAGLLLLPLTA
                     GAVLGSLLSGRYARRTGRCRLFAAAGCAAAAAGAYALSRLGTGTTWPAYALATAALGAG
                     TGLALPALARAVRNSVPAADLAAAGSAGTYLRQLGGALAVASLGALLAHRLAGGPGRSS
                     GPSAPHALTPRLLRALPAELRGGYVRAYADAMPRIFLYLVPVLVLGLLLAFLLKEKPPV
                     SQNLAEAPVIPSARTAPPEEEPPFVPGIPVTGVVQHHDGTTVPRAALTLIDSGGRQIGR
                     GATGEDGRYALSTPGTGSYVLIAAAGGHQPQAVTVTVGERPVELDVVLGGAGRLAGTVL
                     TADGSPVRDALVTLTNVHGEVVASTRTGRDGGYDITELVAGEYTLAGSAPVFRPAALPV
                     TVQSCRETRQDIELAGGAVLRGVVRAGGGRLVEDARVTLLDAAGNVVDTATTGPDGSFR
                     FVDLSAGEYTVIAAGYPPVATVLQVAGGGRTERDLQLGHAD"
     misc_feature    6744..6746
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(8077..8586)
                     /locus_tag="AS857_RS08405"
     CDS             complement(8077..8586)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1160: flavin reductase domain protein FMN-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013756.4"
                     /locus_tag="AS857_RS08405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavin reductase family protein"
                     /protein_id="WP_058042500.1"
                     /transl_table=11
                     /translation="MTTALSPVDPDSYRALMASHPGGVAVVTTDDGLGTPYGFACTAWC
                     GVSLDPPLLLVCASAKGSTLPVLAGRGWFAVNLLHGAGRRAAEAFAHRDAGRFSAVPWQ
                     PSPATGLPLLPEDAHTAAECRVHRLTPAGDHTVIIGEIVRTTTTRSAEEPPLLYGMRRY
                     ATWPVP"
     gene            complement(8583..9821)
                     /locus_tag="AS857_RS08410"
     CDS             complement(8583..9821)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="AS857_RS08410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_058042501.1"
                     /transl_table=11
                     /translation="MRANGQRRLAAAGAPAPALPAVPRTAVPTVTYVLFVVMAGGTLPT
                     PVYALYVQRLHLSPPVVALVFAAYAVGIVAALLLFGGLSDKIGRRATLVPALVVAAASS
                     VVFIALPTLPGLFAGRLLSGVSVGLTTGAATAYLRELHPSPPRAALIASVTNMAGLGSG
                     ALLSGVLVEYAPSPEVLPYTVLIVLLLPGAALVLLPERVVARGGGIRPQRIGVPPAVRR
                     PFAAAAVAVFASFALLGLLAALAGNFLVQGLHNHSHLAVGLVAFSAFGSAGAAQLLAGR
                     MTPRAGLVAGMTAVPLGLALIVTGLSAASLPVFLCGSVLGGAGAGTSFKSGLALVTSQA
                     APDRVSELVSGYFVAAYLGLTVPVVGVAVLLAEGTLMTAAGVFAGVVTVLCLGSIGVTA
                     ALGNRTSTRRTPP"
     gene            complement(9818..11023)
                     /locus_tag="AS857_RS08415"
     CDS             complement(9818..11023)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) azdH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933761.1"
                     /locus_tag="AS857_RS08415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_245699705.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 4.7e-10, bitscore:
                     37.2, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="azdH (E-value: 3.5e-16, bitscore: 56.0,
                     seeds: 3, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.3e-16, bitscore:
                     56.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 6e-14, bitscore:
                     49.6, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMSLPTELLPAEFDELLDVAEATGAALAPFAAEVDAGRSTGHET
                     YRVLREAGLLGLLVPREAGGAGLGFAAYSRVLAVLGAHNGAAALGFNMHNVAIGSLCES
                     AGTPLPPAAEAFRSWLFDEVVHGRKLFASATSEAGSGAKLRGVRTSYRRTEDGGYVITG
                     EKSFVSLAGVADYYVVAARAEGTEGSGEVSHFVVAADDRGVGFGEVHSLSAMYGTSTAG
                     MTLDAVTVPRSRLFLGVEGMSLYKLVREPHWMIAGYTGAYLGIAEAILRFTTDHVAASP
                     RRAASPVLQRELGRMSARLSAARALVAEAGARVDAARGSAEANAAVHAAKYVVGETGPA
                     LAQDAVRICGSVAVSRSQPLERLVREASFASVMPAKPEECLEYLGKAALGVNLYDATAF
                     DW"
     gene            complement(11073..12254)
                     /locus_tag="AS857_RS08420"
     CDS             complement(11073..12254)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933757.1"
                     /locus_tag="AS857_RS08420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_058042502.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4e-21, bitscore:
                     72.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.8e-21, bitscore:
                     74.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAADRLLRSGPPGAEAVVDEYRDRALPLVEQLAGKGFRDQWEAL
                     AGLGVLCLDAPEPGPGASAGAAAPGPVTRSLAMIEGIGLAGADPGVVYAMASQVFGMEY
                     PLRAVLPAGAWRSVARIQEGRELLCHALTERKGGSDPLSMDTRATRDGDGYVLEGAKTF
                     ITAAPVADLALVFARTEQGRSPFSLSAFLFPVATAGVTRAEAFAKTALPGVPMGELAFD
                     GVRLDAGSLVGGEGSGLAILSSTTTWERALLLGYALGPMRRTLQRLTDWASERGHFGRR
                     MGSSHQVAARISDMALVLHRSRTLLYAMAARLDAGTPTRRLSAEAALTKISVSEDYVRL
                     TEHATALSGVRAFIADSELPADLHSPMAALTYAGPNDLLRIGVAREFGLPVEN"
     gene            complement(12376..12639)
                     /locus_tag="AS857_RS39855"
     CDS             complement(12376..12639)
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PP-binding (21-65). E-value: 1.3e-08.
                     Score: 27.0. Matches aSDomain:
                     nrpspksdomains_AS857_RS39855_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="AS857_RS39855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl carrier protein"
                     /protein_id="WP_058042503.1"
                     /sec_met_domain="PP-binding (E-value: 4.5e-08, bitscore:
                     30.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTVEDLCTLISSKITWGRGEEPRQLLPDTPLLEQGLLDSLSIMQ
                     IVAALDAQAGIVLPDTEIVAANFRSPQALWSVLEDLRAGVAR"
     aSDomain        complement(12445..12576)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS39855_PP-binding.1"
                     /evalue="1.30E-08"
                     /label="AS857_RS39855_PP-binding.1"
                     /locus_tag="AS857_RS39855"
                     /protein_end="65"
                     /protein_start="21"
                     /score="27.0"
                     /tool="antismash"
                     /translation="EPRQLLPDTPLLEQGLLDSLSIMQIVAALDAQAGIVLPDTEIVA"
     gene            complement(12674..14269)
                     /locus_tag="AS857_RS08430"
     CDS             complement(12674..14269)
                     /NRPS_PKS="Domain: AMP-binding (14-422). E-value: 1.7e-84.
                     Score: 275.7. Matches aSDomain:
                     nrpspksdomains_AS857_RS08430_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="AS857_RS08430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_058042504.1"
                     /sec_met_domain="AMP-binding (E-value: 4.5e-90, bitscore:
                     299.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLDDVRLDGLLAASARRHPSRPALTAGGRTWTYAELDRAVGDL
                     ARQLRAAGLETGDRVGVLAPKGSEAVLGIYAALRAGAVVAPLDVADPPVRTAHMVRGAG
                     ISLLLAPDRSLEGCRRAAAEAGAGPAPDEGTLDHGLNRVRTLAAADKPAPLPAPAGSGG
                     YVLFTSGSTGRPKGVLLSHANVAHFALWAAAELGLTETDRVGSQAALTFDLTTFDLFST
                     AAAGACAVLMPDVLRAFPRDVVGWLHEQRITAFYAVPSLYQGMLERGGIAEDFPPSLRV
                     AAFAGEPFAPRPLERYLGLLGDVPLYNLYGPTETNVCTYSRVPASWTADQEATIGRAVD
                     GDVVDVLGEDGLPTDGTGEIHVAGATVFQGYLQDGTLTDPTRTVRFRDGVARRAYATGD
                     IGRIAADGRVFLRGRGDTQVKRRGHRIDLLDVESAVLALPGVTAAAVVAKDGAHHGEIW
                     AYVQSDGGGTGAAAAAETSPEETAEGILAGLRGLLPLRMLPDRVVPAAALPVNARGKVD
                     RRALAARTDGPHTA"
     CDS_motif       complement(12860..12895)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08430_0004"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="AS857_RS08430"
                     /protein_end="470"
                     /protein_start="458"
                     /score="-3.3"
                     /tool="antismash"
                     /translation="AYVQSDGGGTGA"
     CDS_motif       complement(12974..13033)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08430_0003"
                     /evalue="2.40E-07"
                     /label="NRPS-A_a8"
                     /locus_tag="AS857_RS08430"
                     /protein_end="432"
                     /protein_start="412"
                     /score="23.2"
                     /tool="antismash"
                     /translation="GRGDTQVKRRGHRIDLLDVE"
     aSDomain        complement(13004..14227)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08430_AMP-binding.1"
                     /evalue="1.70E-84"
                     /label="AS857_RS08430_AMP-binding.1"
                     /locus_tag="AS857_RS08430"
                     /protein_end="422"
                     /protein_start="14"
                     /score="275.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ASARRHPSRPALTAGGRTWTYAELDRAVGDLARQLRAAGLETGDR
                     VGVLAPKGSEAVLGIYAALRAGAVVAPLDVADPPVRTAHMVRGAGISLLLAPDRSLEGC
                     RRAAAEAGAGPAPDEGTLDHGLNRVRTLAAADKPAPLPAPAGSGGYVLFTSGSTGRPKG
                     VLLSHANVAHFALWAAAELGLTETDRVGSQAALTFDLTTFDLFSTAAAGACAVLMPDVL
                     RAFPRDVVGWLHEQRITAFYAVPSLYQGMLERGGIAEDFPPSLRVAAFAGEPFAPRPLE
                     RYLGLLGDVPLYNLYGPTETNVCTYSRVPASWTADQEATIGRAVDGDVVDVLGEDGLPT
                     DGTGEIHVAGATVFQGYLQDGTLTDPTRTVRFRDGVARRAYATGDIGRIAADGRVFLRG
                     RGDTQVKRR"
     CDS_motif       complement(13136..13201)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08430_0002"
                     /evalue="3.00E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="AS857_RS08430"
                     /protein_end="378"
                     /protein_start="356"
                     /score="19.6"
                     /tool="antismash"
                     /translation="TGEIHVAGATVFQGYLQDGTLT"
     CDS_motif       complement(13724..13780)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08430_0001"
                     /evalue="9.20E-10"
                     /label="NRPS-A_a3"
                     /locus_tag="AS857_RS08430"
                     /protein_end="182"
                     /protein_start="163"
                     /score="30.5"
                     /tool="antismash"
                     /translation="YVLFTSGSTGRPKGVLLSH"
     gene            complement(14266..15060)
                     /locus_tag="AS857_RS08435"
     CDS             complement(14266..15060)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (23-138). E-value:
                     4.6e-14. Score: 44.6. Matches aSDomain:
                     nrpspksdomains_AS857_RS08435_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="AS857_RS08435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_058042505.1"
                     /sec_met_domain="PF00561 (E-value: 1.8e-11, bitscore: 41.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.3e-19, bitscore:
                     68.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTIAISRGPVEYTVLEGDSEAAPLVLLHEGLGCIAMWRRFPARL
                     AAATGRRALVFSRHGHGGSGPAPQERTPRSLHEEAHEVLPELLDRLGVHRPVLVGHSEG
                     ASIALLHAAEHPVEAVVAVAPHLFAEPQTLRGVAAAREAHASGPLAKELAFYHQDPLTV
                     FRRWSGLWLSEAFRGWDIEGDLAGATAPVLLVQGDSDPYGTFAHLDAAERALGGPVQRL
                     ELAGCGHAPHLERPDDVVDAVQTFLATAPGPAGPPPRQETRP"
     aSDomain        complement(14647..14991)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08435_Abhydrolase_1.1"
                     /evalue="4.60E-14"
                     /label="AS857_RS08435_Abhydrolase_1.1"
                     /locus_tag="AS857_RS08435"
                     /protein_end="138"
                     /protein_start="23"
                     /score="44.6"
                     /tool="antismash"
                     /translation="PLVLLHEGLGCIAMWRRFPARLAAATGRRALVFSRHGHGGSGPAP
                     QERTPRSLHEEAHEVLPELLDRLGVHRPVLVGHSEGASIALLHAAEHPVEAVVAVAPHL
                     FAEPQTLRGVA"
     misc_feature    15158..15167
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.59"
                     /tool="antismash"
     misc_feature    complement(15216..15228)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    15235..15248
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.21"
                     /tool="antismash"
     misc_feature    15332..15347
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.64"
                     /tool="antismash"
     gene            15477..16313
                     /locus_tag="AS857_RS08440"
     CDS             15477..16313
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513453.1"
                     /locus_tag="AS857_RS08440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M55 family metallopeptidase"
                     /protein_id="WP_058044003.1"
                     /transl_table=11
                     /translation="MKILISADMEGATGVTWPADVLPGASQWERCRHLFTSDVNAAVAG
                     FFDGGADEVLINEAHWGMRNLLLEKLDDRAQMLTGKHKSLSMVEGVQHGDVDGIAFVGY
                     HTGAGTPGVLAHTYLANTITGVWVDGARASEGLLNSLVVAEYGVPVVLVTGDDLTCADA
                     KGYAPLARSVAVKDCVSRYAAVCRTPARTAADIRAAAREATALAVRYEPVTGGGPFTVD
                     IEFDADHLAGAATVIPGVVPSGERRVSYTTATMYDGIRCFKAVTTVVSAAVEEQYG"
     gene            16306..17676
                     /locus_tag="AS857_RS08445"
     CDS             16306..17676
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537460.1"
                     /locus_tag="AS857_RS08445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="WP_058042506.1"
                     /transl_table=11
                     /translation="MAEITTEEAVGPEGAEVRVDERALDEAVCFTSDLIRIDTTNRGAG
                     DCRERPAAEYVAAALSGAGIEPVLLEKEPGRTNVVARVPGTDPGAPALLVHGHLDVVPA
                     DPAEWSVHPFSGEIRDGVVWGRGAVDMKNTDAMVLSVVRAWARTGARPPCDIVLAFTAD
                     EEDRAWTGAAFLAEEHPGLFEGCRYAIGESGAYTFHADGGLRLYPVAAGERGTAWLKLT
                     ARGRAGHGSKPNQANAVTRLAEALARIGRHRWPVRLSPVVSAALVEIAALHGIEADPGA
                     PGFDADALLEELGSASRLLAPTVRNSSNPTMLDAGYKVNVIPGAAVGHVDGRVVPGGEE
                     EFRTTLDRLTGPHVEWEYYQKGTALQAPLATPLFSLMREALERFDPDGHAVPFCMSGGT
                     DANQFSRLGIDCYGFAPLKLPPGFDYQALFHGVDERVPCDALHFGVRVLDHFLMNAA"
     gene            17790..19778
                     /locus_tag="AS857_RS08450"
     CDS             17790..19778
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890479.1"
                     /locus_tag="AS857_RS08450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="WP_058042507.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 1e-42, bitscore:
                     143.1, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSTAPYGAWQSPVGAELAASAGGGPDFVGTVGDELWWAAPRPAE
                     EGRFTLVRRRAGGAEETVLPAPWNVRNRVLEYGGLPWAAVARASGGPLVVFTHFADQRL
                     YAFEPDVPGAVPRPLTPLSSVGGGLRWADPVLLPGRGEVWCVLEEFTGEGPCDVRRLLT
                     AVPLDGSAARDRGAVRELTDGGNRFVTGPRLSPDGRQAAWIAWDHPRMPWEGTELKTAQ
                     VSADGRLADARTVMGGPAESVAQVEWAEDGSLVAASDRTGWWNLYRVDPATGESTALCR
                     REEEFAGPLWRVGVRWFAPLPGGLVAALHGRGAAVLGVLDPRSGEIADVAGPWTEWAPT
                     LAVSGTRAVGVAASPHSAYEVVELDVCTGRARTVGARHTDRVDPAYYPEPLTRTFGGPD
                     GREVHAHLHPPRNPGHAAPDGELPPYAVWAHGGPTARTPLVLDLAVAFFTSRGIGVAEV
                     NYGGSTGYGRAYRERLRGQWGVVDVEDCAAVAAALAREGIADPARIAIRGGSAGGWTAA
                     ASLAATSLYACGTILYPVLDPEAWTAEGGTHDFESRYLESLIGPREEVPERYRERSPLH
                     RASRISAPFLLLQGLADPVCPPAQSERLLAAMAGRGVPHTYIAFEGEGHGFRRAATVVR
                     ALEAELSLYAQTFGVAAPGMAVLELVT"
     misc_feature    complement(19852..19870)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: strong, score: 33.62"
                     /tool="antismash"
     misc_feature    complement(19854..19874)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.29"
                     /tool="antismash"
     misc_feature    19953..19971
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: medium, score: 29.03"
                     /tool="antismash"
     gene            20001..20780
                     /locus_tag="AS857_RS08455"
     CDS             20001..20780
                     /EC_number="1.3.1.28"
                     /GO_function="GO:0008667 -
                     2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (10-166). E-value: 1.1e-13.
                     Score: 43.4. Matches aSDomain:
                     nrpspksdomains_AS857_RS08455_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: EntA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004954196.1"
                     /locus_tag="AS857_RS08455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase"
                     /protein_id="WP_058042508.1"
                     /sec_met_domain="EntA (E-value: 3.2e-114, bitscore: 377.9,
                     seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 7.7e-36, bitscore:
                     120.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.8e-30, bitscore:
                     103.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQQSELSGRIALVTGAGQGIGEAVTRALVARGARVAALDWTPDGI
                     KDLEAEFGRDKVTAHTADVADSAAVEAVVEEVEDTLGPLAILVNVAGVLRTSPVVDITD
                     DTWHRTFAVNSTGVFNASRAAARRMTERRSGCIVTVGSNAAGVPRTSMAAYAASKAAAT
                     MFTKCLGLELARSGIRCNVVSPGSTDTAMQRGLWADEEAPQRVIDGDPGSYRVGIPLGR
                     IAEPADIADAVAFLVSDRARHITMHDLYVDGGATLRA"
     aSDomain        20031..20498
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08455_PKS_KR.1"
                     /evalue="1.10E-13"
                     /label="AS857_RS08455_PKS_KR.1"
                     /locus_tag="AS857_RS08455"
                     /protein_end="166"
                     /protein_start="10"
                     /score="43.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGAGQGIGEAVTRALVARGARVAALDWTPDGIKDLEAEFGRD
                     KVTAHTADVADSAAVEAVVEEVEDTLGPLAILVNVAGVLRTSPVVDITDDTWHRTFAVN
                     STGVFNASRAAARRMTERRSGCIVTVGSNAAGVPRTSMAAYAASKAAATMFT"
     CDS_motif       20034..20102
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08455_0001"
                     /evalue="1.90E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="AS857_RS08455"
                     /protein_end="34"
                     /protein_start="11"
                     /score="14.1"
                     /tool="antismash"
                     /translation="LVTGAGQGIGEAVTRALVARGAR"
     CDS_motif       20367..20423
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08455_0002"
                     /evalue="4.90E+00"
                     /label="PKSI-KR_m1"
                     /locus_tag="AS857_RS08455"
                     /protein_end="141"
                     /protein_start="122"
                     /score="-0.0"
                     /tool="antismash"
                     /translation="RAAARRMTERRSGCIVTVG"
     misc_feature    20842..20851
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.17"
                     /tool="antismash"
     misc_feature    complement(20980..20989)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 12.89"
                     /tool="antismash"
     gene            21029..22249
                     /gene="dhbC"
                     /locus_tag="AS857_RS08460"
     CDS             21029..22249
                     /codon_start=1
                     /gene="dhbC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: EntC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1018: isochorismate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004954199.1"
                     /locus_tag="AS857_RS08460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isochorismate synthase DhbC"
                     /protein_id="WP_058042509.1"
                     /sec_met_domain="EntC (E-value: 2.6e-146, bitscore: 485.0,
                     seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAHHVADRPGGSEPGTPVGGDTVGAATSLLDAYEPGRARFFAS
                     PTRTLLAHGVRAEVPHGAAPVAQRVAETLAARVLAGDEAPVVVGAVPFDQGAPAALAVP
                     EAVRWAPPLAEDPLIALPAAAPGAARWDVRPVPEPAGYGAAVAEAVGRMQRGDFAKVVL
                     ARTLELSSDRDLDLPALLQRLARRDPAGYTFALPTGPGRTLLGASPELLVSRRGGTLVA
                     NPLAGSTPRSADLAEDVRRAAALLQSEKDLHEHAVVVDAVREALAPYCRTLHVPERPTL
                     VRTAAMWHLSTTVTGEPADPAVSALELASALHPTPAVCGTPTTTARDVIGELEPFDRGF
                     FTGMVGWGDANGDGEWVVTIRCAEAEERTLRLYAGAGVVAQSSPEAETAETGAKFQTFL
                     QAVGVDQ"
     gene            22246..23892
                     /locus_tag="AS857_RS08465"
     CDS             22246..23892
                     /EC_number="6.2.1.71"
                     /GO_function="GO:0008668 - (2,3-dihydroxybenzoyl)adenylate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (33-441). E-value: 2.8e-88.
                     Score: 288.2. Matches aSDomain:
                     nrpspksdomains_AS857_RS08465_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453341.1"
                     /locus_tag="AS857_RS08465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="(2,3-dihydroxybenzoyl)adenylate synthase"
                     /protein_id="WP_058042510.1"
                     /sec_met_domain="AMP-binding (E-value: 6.3e-93, bitscore:
                     308.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETTDAPGYPAEFAERYRAAGYWRGETFGQMLRDRAQAHPDRIA
                     IVDPAGEGRRWTYGDLDLRADRLAAGFLAHGIGKGDRVVVQLPNVAEFFEVVFALFRIG
                     ALPVFALPAHRETEIRHFCAFTEAAAYVIADVSEGYDYRELATKVRAEVPGLKHVFVAG
                     EPGEHTALAGLPTEPVAVENAPAPHELAFLQLSGGSTGVPKLIPRTHDDYIYSLWGSNE
                     ICGVDENSVYLCALPAAHNFPLSSPGTLGALYAGARVVLAPRPSPDVAFPLIAAEGVTI
                     TGLVPPLALVWTEAAAETPHDLSSLQVLLVGGAKFSEEAARRVRPALGCTLQQVFGMAE
                     GLVNYTRLDDPEATIVTTQGRPISPDDEIRIVDDEDNELPAGETGHLLTRGPYTIRGYW
                     RAPEHNATAFTADGFYRTGDVVRMTETGHIVVEGRAKDQINRGGEKVAAEEIENHILAH
                     PAVHDVAVVSMPDAYLGERTCAYVVLREGAEPVKSIAVKKFVRERGLAAFKVPDRVEFV
                     TEFPQTGIGKVSKKDLRAAIAAQVAAAAAQH"
     aSDomain        22345..23568
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08465_AMP-binding.1"
                     /evalue="2.80E-88"
                     /label="AS857_RS08465_AMP-binding.1"
                     /locus_tag="AS857_RS08465"
                     /protein_end="441"
                     /protein_start="33"
                     /score="288.2"
                     /specificity="substrate consensus: diOH-Bz"
                     /tool="antismash"
                     /translation="RDRAQAHPDRIAIVDPAGEGRRWTYGDLDLRADRLAAGFLAHGIG
                     KGDRVVVQLPNVAEFFEVVFALFRIGALPVFALPAHRETEIRHFCAFTEAAAYVIADVS
                     EGYDYRELATKVRAEVPGLKHVFVAGEPGEHTALAGLPTEPVAVENAPAPHELAFLQLS
                     GGSTGVPKLIPRTHDDYIYSLWGSNEICGVDENSVYLCALPAAHNFPLSSPGTLGALYA
                     GARVVLAPRPSPDVAFPLIAAEGVTITGLVPPLALVWTEAAAETPHDLSSLQVLLVGGA
                     KFSEEAARRVRPALGCTLQQVFGMAEGLVNYTRLDDPEATIVTTQGRPISPDDEIRIVD
                     DEDNELPAGETGHLLTRGPYTIRGYWRAPEHNATAFTADGFYRTGDVVRMTETGHIVVE
                     GRAKDQINR"
     CDS_motif       23383..23472
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08465_0001"
                     /evalue="1.20E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="AS857_RS08465"
                     /protein_end="409"
                     /protein_start="379"
                     /score="17.7"
                     /tool="antismash"
                     /translation="PAGETGHLLTRGPYTIRGYWRAPEHNATAF"
     gene            23919..24551
                     /locus_tag="AS857_RS08470"
     CDS             23919..24551
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091628.1"
                     /locus_tag="AS857_RS08470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="isochorismatase family protein"
                     /protein_id="WP_058042511.1"
                     /transl_table=11
                     /translation="MALPAIAPYPMPREADLPANKVGWTVDPSRAVLLVHDLQNYFLDA
                     FEAGASPVTELLANVAAVKKDCERLGVPVVYSAQPGGQSPAERGLQQDFWGPGLPDDER
                     AKAIADAVAPTAADTVLTKWKYSAFVRTDLAERMAAQGRDQLIIVGVYAHIGVMMSACD
                     AWMRDIQSFLVADAVADFSAEDHAMALRWAAAKCAVVTTTDRLFEGA"
     gene            24557..24787
                     /locus_tag="AS857_RS08475"
     CDS             24557..24787
                     /NRPS_PKS="Domain: PP-binding (5-69). E-value: 3.5e-16.
                     Score: 51.3. Matches aSDomain:
                     nrpspksdomains_AS857_RS08475_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018091629.1"
                     /locus_tag="AS857_RS08475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_058042512.1"
                     /sec_met_domain="PP-binding (E-value: 2.8e-14, bitscore:
                     50.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALTLEQIRADVADVLGEDPADIPDDENLVDYGLDSVRIMTLVER
                     WRRDHGTEVTFVALAEQPAIEQWAPLLGAGT"
     aSDomain        24572..24763
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08475_PP-binding.1"
                     /evalue="3.50E-16"
                     /label="AS857_RS08475_PP-binding.1"
                     /locus_tag="AS857_RS08475"
                     /protein_end="69"
                     /protein_start="5"
                     /score="51.3"
                     /tool="antismash"
                     /translation="EQIRADVADVLGEDPADIPDDENLVDYGLDSVRIMTLVERWRRDH
                     GTEVTFVALAEQPAIEQWA"
     gene            24823..28917
                     /locus_tag="AS857_RS08480"
     CDS             24823..28917
                     /NRPS_PKS="Domain: Condensation_Starter (14-317). E-value:
                     1.9e-106. Score: 347.7. Matches aSDomain:
                     nrpspksdomains_AS857_RS08480_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (481-880). E-value:
                     7.7e-110. Score: 359.2. Matches aSDomain:
                     nrpspksdomains_AS857_RS08480_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (997-1043). E-value: 2.2e-17. Score:
                     55.0. Matches aSDomain: nrpspksdomains_AS857_RS08480_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1110-1360). E-value:
                     3.3e-36. Score: 117.8. Matches aSDomain:
                     nrpspksdomains_AS857_RS08480_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRP-metallophore: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981755.1"
                     /locus_tag="AS857_RS08480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid adenylation domain-containing protein"
                     /protein_id="WP_275477365.1"
                     /sec_met_domain="Condensation (E-value: 1.5e-49, bitscore:
                     165.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 3.1e-117, bitscore:
                     388.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 6.1e-09, bitscore:
                     33.4, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 8.4e-25, bitscore:
                     85.3, seeds: 16, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTSGAGRSPAPEGLPLTAAQSGMWFAQALDPGSPALGTAEYLE
                     IHGDIDPARFAEALHRTVGEADALRVRITDAPGGPRQLPIAVEAPGHGFPLHTADLRDE
                     RDPDASALARMRADLAEPFDLARGPLFSHALFRVGDERWLWYQRVHHAVLDGYGYSLVA
                     RRVAELYTALATGEDPAPSPFGRLADLVAEDAAYRESATRTRDRAHWLTVFADRPEAPS
                     LASAGPAARPALPSRSHLRATAHLAPEATARLRRLAASVRATWTDVLFAAQALYVARAT
                     RSEDVVLGLPMMGRMGSVALRVPGMVMNVLPLRMTVTPGTTFAELVHQAVLGIRAARRH
                     QRYRYEDIRRDLGLLGEGRPLTGPLVNVMPFDYGLTFAGARSDAHNLAPGPVDDLTVGI
                     YDRADGSGLRIDYDANPARYGQDELAAHQARFLDLLTRLAERDPHLPLGGLPLATDAER
                     EQVLAEFNDTATEVPPTTLIGPVEARAARTPHATALVDGDLTLTYAALNARANRLARHL
                     RTLGVAPGTLAAVALPCSTELVVALLAVLKAGGAYVPLDTADPAVRLRGMLDTAAPVCV
                     LTDRAGAAALPAGAAPVVVLDDPALGEALAAHLPTDPGRALTPQHPAYVLHTSGTTGAP
                     KGVVVPHSAIDNRLRWMQAQYPLAPGDRVLHKTPVGFDVSVWELFWPLREGATLVLAGP
                     GAHRDPAELARTVREQGVTVTHFVPSVLQLFLAAPGAAACTGLRHVFSSGEVLPRATAE
                     EFHRLLPGTALHNLYGPTEAAVDVTHHTCRPGATGPVPIGRPAWNTRLYILDAALQPCP
                     PGVPGELHLAGAQLATGYLGRPDLTAERFVDDPFAGPGARMYRTGDLARWREDGEAEYL
                     GRTDRQVKLHGRRIEPDGVEAVLLADPRVQAACAVVREDRPGDRRLVAYVTPVSADAAA
                     ETGTLLRPAPDALRESLAAQLPEAMVPSAVVVLDAFPTGPNGKLDRAALPAPGPQADAG
                     GRAPAGPREETLTRLFAEVLGLPHVGVDDSFFALGGTSLLAARLVARVRDVFGEGVGVI
                     ADSAGGGADDGEDGPFAMGALFRAPTPAALARRLGGGTDVTAGLDGAPLEPVLPLRATG
                     SRTPLFALPPAAGLGWCYASLLAGLGPDQPLHALRARGLTPGEPLPATLEEMAADHAER
                     IRAVQPQGPYRLLGWSAGGVLAHAVAVRLQEAGEKVELLAMLDAYPAAAAFEEQAVLGA
                     LLDMAGCAQADGAPLTRDGVLAALRADGGAFAALTPRMLQAVVDVALGTTALAGRHQHR
                     VFDGDVLFFTATGTATATGTGTDGDGPRAPGAGSVTREAWRPYVTGRVINRDIACPHAH
                     MTQPGPAAEVAEAVTRHLGES"
     aSDomain        24865..25773
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08480_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="1.90E-106"
                     /label="AS857_RS08480_Condensation_Starter.1"
                     /locus_tag="AS857_RS08480"
                     /protein_end="317"
                     /protein_start="14"
                     /score="347.7"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHAVLDG"
                     /tool="antismash"
                     /translation="GLPLTAAQSGMWFAQALDPGSPALGTAEYLEIHGDIDPARFAEAL
                     HRTVGEADALRVRITDAPGGPRQLPIAVEAPGHGFPLHTADLRDERDPDASALARMRAD
                     LAEPFDLARGPLFSHALFRVGDERWLWYQRVHHAVLDGYGYSLVARRVAELYTALATGE
                     DPAPSPFGRLADLVAEDAAYRESATRTRDRAHWLTVFADRPEAPSLASAGPAARPALPS
                     RSHLRATAHLAPEATARLRRLAASVRATWTDVLFAAQALYVARATRSEDVVLGLPMMGR
                     MGSVALRVPGMVMNVLPLRMTV"
     aSModule        24865..28902
                     /complete
                     /domains="nrpspksdomains_AS857_RS08480_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_AS857_RS08480_AMP-binding.1"
                     /domains="nrpspksdomains_AS857_RS08480_PCP.1"
                     /domains="nrpspksdomains_AS857_RS08480_Thioesterase.1"
                     /final_module
                     /locus_tags="AS857_RS08480"
                     /monomer_pairings="Ser -> Ser"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       24868..24909
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08480_0001"
                     /evalue="5.00E-04"
                     /label="C1_starter_004-017"
                     /locus_tag="AS857_RS08480"
                     /protein_end="29"
                     /protein_start="15"
                     /score="12.7"
                     /tool="antismash"
                     /translation="LPLTAAQSGMWFAQ"
     CDS_motif       24940..25047
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08480_0002"
                     /evalue="1.10E-14"
                     /label="C2_starter_024-063"
                     /locus_tag="AS857_RS08480"
                     /protein_end="75"
                     /protein_start="39"
                     /score="46.9"
                     /tool="antismash"
                     /translation="TAEYLEIHGDIDPARFAEALHRTVGEADALRVRITD"
     CDS_motif       25267..25332
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08480_0003"
                     /evalue="3.70E-10"
                     /label="C3_starter_134-155"
                     /locus_tag="AS857_RS08480"
                     /protein_end="170"
                     /protein_start="148"
                     /score="32.5"
                     /tool="antismash"
                     /translation="VHHAVLDGYGYSLVARRVAELY"
     CDS_motif       25675..25764
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08480_0004"
                     /evalue="6.90E-15"
                     /label="C5_starter_265-294"
                     /locus_tag="AS857_RS08480"
                     /protein_end="314"
                     /protein_start="284"
                     /score="47.2"
                     /tool="antismash"
                     /translation="DVVLGLPMMGRMGSVALRVPGMVMNVLPLR"
     CDS_motif       25822..25926
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08480_0005"
                     /evalue="2.90E-17"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="AS857_RS08480"
                     /protein_end="368"
                     /protein_start="333"
                     /score="55.1"
                     /tool="antismash"
                     /translation="IRAARRHQRYRYEDIRRDLGLLGEGRPLTGPLVNV"
     aSDomain        26266..27462
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08480_AMP-binding.1"
                     /evalue="7.70E-110"
                     /label="AS857_RS08480_AMP-binding.1"
                     /locus_tag="AS857_RS08480"
                     /protein_end="880"
                     /protein_start="481"
                     /score="359.2"
                     /specificity="substrate consensus: Ser"
                     /tool="antismash"
                     /translation="EARAARTPHATALVDGDLTLTYAALNARANRLARHLRTLGVAPGT
                     LAAVALPCSTELVVALLAVLKAGGAYVPLDTADPAVRLRGMLDTAAPVCVLTDRAGAAA
                     LPAGAAPVVVLDDPALGEALAAHLPTDPGRALTPQHPAYVLHTSGTTGAPKGVVVPHSA
                     IDNRLRWMQAQYPLAPGDRVLHKTPVGFDVSVWELFWPLREGATLVLAGPGAHRDPAEL
                     ARTVREQGVTVTHFVPSVLQLFLAAPGAAACTGLRHVFSSGEVLPRATAEEFHRLLPGT
                     ALHNLYGPTEAAVDVTHHTCRPGATGPVPIGRPAWNTRLYILDAALQPCPPGVPGELHL
                     AGAQLATGYLGRPDLTAERFVDDPFAGPGARMYRTGDLARWREDGEAEYLGRTDRQVKL
                     "
     CDS_motif       26449..26490
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08480_0006"
                     /evalue="2.70E-06"
                     /label="NRPS-A_a2"
                     /locus_tag="AS857_RS08480"
                     /protein_end="556"
                     /protein_start="542"
                     /score="20.3"
                     /tool="antismash"
                     /translation="LAVLKAGGAYVPLD"
     CDS_motif       26572..26601
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08480_0007"
                     /evalue="1.60E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="AS857_RS08480"
                     /protein_end="593"
                     /protein_start="583"
                     /score="0.0"
                     /tool="antismash"
                     /translation="AALPAGAAPV"
     CDS_motif       26689..26748
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08480_0008"
                     /evalue="1.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="AS857_RS08480"
                     /protein_end="642"
                     /protein_start="622"
                     /score="26.7"
                     /tool="antismash"
                     /translation="AYVLHTSGTTGAPKGVVVPH"
     CDS_motif       27256..27345
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08480_0009"
                     /evalue="2.20E-16"
                     /label="NRPS-A_a6"
                     /locus_tag="AS857_RS08480"
                     /protein_end="841"
                     /protein_start="811"
                     /score="51.9"
                     /tool="antismash"
                     /translation="PPGVPGELHLAGAQLATGYLGRPDLTAERF"
     CDS_motif       27430..27495
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08480_0010"
                     /evalue="4.70E-08"
                     /label="NRPS-A_a8"
                     /locus_tag="AS857_RS08480"
                     /protein_end="891"
                     /protein_start="869"
                     /score="25.4"
                     /tool="antismash"
                     /translation="YLGRTDRQVKLHGRRIEPDGVE"
     aSDomain        27814..27951
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08480_PCP.1"
                     /evalue="2.20E-17"
                     /label="AS857_RS08480_PCP.1"
                     /locus_tag="AS857_RS08480"
                     /protein_end="1043"
                     /protein_start="997"
                     /score="55.0"
                     /tool="antismash"
                     /translation="EETLTRLFAEVLGLPHVGVDDSFFALGGTSLLAARLVARVRDVFG
                     E"
     aSDomain        28153..28902
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08480_Thioesterase.1"
                     /evalue="3.30E-36"
                     /label="AS857_RS08480_Thioesterase.1"
                     /locus_tag="AS857_RS08480"
                     /protein_end="1360"
                     /protein_start="1110"
                     /score="117.8"
                     /tool="antismash"
                     /translation="PLFALPPAAGLGWCYASLLAGLGPDQPLHALRARGLTPGEPLPAT
                     LEEMAADHAERIRAVQPQGPYRLLGWSAGGVLAHAVAVRLQEAGEKVELLAMLDAYPAA
                     AAFEEQAVLGALLDMAGCAQADGAPLTRDGVLAALRADGGAFAALTPRMLQAVVDVALG
                     TTALAGRHQHRVFDGDVLFFTATGTATATGTGTDGDGPRAPGAGSVTREAWRPYVTGRV
                     INRDIACPHAHMTQPGPAAEVAEAVTRH"
     CDS_motif       28333..28407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08480_0011"
                     /evalue="3.20E-14"
                     /label="NRPS-te1"
                     /locus_tag="AS857_RS08480"
                     /protein_end="1195"
                     /protein_start="1170"
                     /score="45.1"
                     /tool="antismash"
                     /translation="QPQGPYRLLGWSAGGVLAHAVAVRL"
     gene            28917..29660
                     /locus_tag="AS857_RS08485"
     CDS             28917..29660
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008897 - holo-[acyl-carrier-protein]
                     synthase activity [Evidence IEA]"
                     /NRPS_PKS="Domain: ACPS (135-197). E-value: 5.9e-09. Score:
                     27.8. Matches aSDomain:
                     nrpspksdomains_AS857_RS08485_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055740.1"
                     /locus_tag="AS857_RS08485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_079110179.1"
                     /transl_table=11
                     /translation="MRVSDGPGTAPRVLGEDSLPGVWTPGPPHVWLLRTDRPLPGPVQD
                     PERILDAGERARAAAFVRDLHRERYVASHTGLRLLLGAYLATDPAAVELVREPCPGCGG
                     PHGRPAAAGAPLHFNLSHAGDLALVAFADTPVGADVEEVQPAGTARELAGVLHPAETAE
                     LAALPAPRLPEAFARCWTRKEAYLKGTGTGLSENPSVTYVGTGPVPASPAGWALEDVPA
                     APGYAAAIAVAVTGAVTGAAANAPR"
     aSDomain        29322..29507
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08485_ACPS.1"
                     /evalue="5.90E-09"
                     /label="AS857_RS08485_ACPS.1"
                     /locus_tag="AS857_RS08485"
                     /protein_end="197"
                     /protein_start="135"
                     /score="27.8"
                     /tool="antismash"
                     /translation="VGADVEEVQPAGTARELAGVLHPAETAELAALPAPRLPEAFARCW
                     TRKEAYLKGTGTGLSEN"
     gene            29911..30612
                     /locus_tag="AS857_RS39860"
     CDS             29911..30612
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AS857_RS39860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_058042513.1"
                     /transl_table=11
                     /translation="MIRSTAALLGAGLVVTSIVLMANGNSRGSTPGIAGATTAPPSTPP
                     PSPPSAPPSAPPSAGPSPGTPAPPPPAVPPTAPAPGSTRSATAALLERVPDAIRPSCSD
                     GDASKFPPSVVAVVACTPPGGFPVIYAQFVDGISTSGAYDRLIGNATVTHDACGPSVPL
                     DGRQRYKVGGKTVGDLTCYGTSDGDAYLTWSSEDLNIIAEAHAPLASYGRLCAWWMTAG
                     PLHGTGAGAAA"
     gene            30686..32809
                     /locus_tag="AS857_RS08495"
     CDS             30686..32809
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1173: WD-40
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF024180.4"
                     /locus_tag="AS857_RS08495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CHAT domain-containing protein"
                     /protein_id="WP_144440759.1"
                     /transl_table=11
                     /translation="MLEVSGGPGGRYTVAVSSPAGEGSLSVALDPDAIGARLADLQRAV
                     LASSVTPRAAALGLERPVREVGERLFRAVFDGRLRGLYLASRQHAGERDEALRVVLRIR
                     APELAALPWELLYDEESGEYLCLRRPLVRYVDLPEPLAPLRSEPPLKILGMTSLPRSRA
                     PLGAESERAALSVALGPLTERGLVHLDWVPGQTAEDLSRRLLRGCHVLHFIGHGAYDPQ
                     RREGMVTLADADGREHHLHATALASLLSVARPRPQLVILNSCQSGMGNAEDLFSSTAAV
                     LVRTVPAVVAMQFAVTDKAATRFAASFYQALAQGRTVDEAVRVGRIALVVDKDDSLEWA
                     TPVLYLRGGDARLFDMPAVWAEAGPAVPPAGAGPVPPKPHTPPEAADGRPAAADGPPQA
                     PGGTPAPPGGPPEAPGAVITSRVLDTRQWVHALAFHPDGRRLATGSRNRVRVWDALTGN
                     RIWEQPVGGWLSSVFAAAFSPGGRRLVTGGADNTVRIWASSNGEELLRLRHDHVVFGVA
                     FSPDGFRVASASADRTVRLWDSTSGDPMLRITHDQVVTDVAFSPDGARLASASADRSVR
                     LWSLGGDALLRLRHDHAVKAVAFSPDGGRLATAGDDGCVRVWDAGSGHQLLLVRHGDAV
                     KDVAFSPGGHWLATASADRTAGVWAVADGTRILRVQHHHTVFCVAFGPDGGWLASGSED
                     KTVKLTPVPGERG"
     gene            complement(32874..33272)
                     /locus_tag="AS857_RS08500"
     CDS             complement(32874..33272)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AS857_RS08500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_058042515.1"
                     /transl_table=11
                     /translation="MKRTIILAMAAVAALTGGLVTTASAENAADDKPVVSADKAKEFAE
                     DGPEIGGFDQVEGPPVTVAPQANGRAVATCPAGRVPSGGGGKTSAFRIFFTDSFQEGGT
                     WVVRGTNTNPAGGASETIRAVAICTAPR"
     misc_feature    complement(33578..33591)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.88"
                     /tool="antismash"
     gene            33665..35194
                     /locus_tag="AS857_RS08505"
     CDS             33665..35194
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AS857_RS08505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_058042516.1"
                     /transl_table=11
                     /translation="MPDPITISIEPYQEGTATASSLAGDLVALPAVRERLSGPRLNVAD
                     FRLLEKDAGTDAPFRAVVHDPDAYRSVEVTGRLGDLAGATARSVRFQPLPDREEFDRAV
                     EAVCAHAEFGPQLAADGALAYRPMPPLADITHADGTVDRVVTVGLRTPGSEVKHRIVGV
                     RTKDGTVIPAPEGVSAPSALDCVTIPPADNCPDPSGGPRAVRVRVSRGTTELWNLVVNR
                     PRTSSGVNGSGAELRFVDYKGERVLYQAHAPILNVRYTGDRCGPFRDWANEEVCFNATG
                     SDPVGPGYRLCTSAPRTILDTHSDQGNFRGVAFFHDGSALRIVSELAAGWYRYVTEWRL
                     ADDGTILPRFGFSAVTNPCTCLAHTHHVYWRLDLDVGGSTANRVDEFNDATGWTPVRLE
                     TQRTRNPAGHRQWRVVAPATGRGYVLVPGANDGTADAYGVADLWVLRYRGTEIDDGRPS
                     DTRAHIGDFVNGESVDGQDLVVWYGAHFFHDEAGPPPPSHVVGPDLRPVVV"
     gene            35240..35809
                     /locus_tag="AS857_RS08510"
     CDS             35240..35809
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602128.1"
                     /locus_tag="AS857_RS08510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family protein"
                     /protein_id="WP_058042517.1"
                     /transl_table=11
                     /translation="MSDHQTAGARARVLAEGPRVVIRAVTPEDGPEFTRLVRDSADLHH
                     PWLSMPTTEERFAQYAARFDGEQRAGFLVCLRDSGRPAGFVNINNIVRGAFQCGALGYG
                     AFVPSAGRGLMGEGFGLVLRHAFGPLGLHRLEANIQPGNTASLALVKRHGFRLEGFSPE
                     FLFIGGAWRDHERWAITADMLQEHQD"
     gene            35861..37876
                     /locus_tag="AS857_RS08515"
     CDS             35861..37876
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014175383.1"
                     /locus_tag="AS857_RS08515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5107 domain-containing protein"
                     /protein_id="WP_058042518.1"
                     /transl_table=11
                     /translation="MPTTIRRAVLSLPAAPLGAEDPLPSLRTAADVHRIDAEQRRALPP
                     DMARQAGHAPLRSLLPVRRRDGYSRRRTPADLEAIVIENDRLRATVLPGLGGRVHSLEH
                     KPTGRELLHRNPVLQPASFALNGAWFSGGIEWNIGATGHTTLSVAPLHAARVPAPDGGE
                     MLRLWEWERLRDLPFQVDLWLPDGSDFLYVGVRIRNPHDRPAPVYWWSNIAVPEEAGTR
                     VLAPAEAAWRFGYERSLSRVPVPEWDGADRTYPLNSTHASDFFYDVPGGERRWIASLDA
                     DGHGLVQTSTDLLRGRKLFVWGSGRGGRRWQEWLTEPGTGGYAEIQAGLARTQLEHVPL
                     EAGGAFAWLEAYGPLAADPAAVHGGDWAAARGEAAARLEAALPRADVEAAYAAWRPYAD
                     AEPKESLHTGSGWGALEAERGHYDLPGTPFAPETLGEEQEPWLEFLHRGEFPRPDRSLP
                     PGPSLVSPRWRELLETIGDGDLCGAYHLGVARWHTGDRSQAVRAWEAAGGLWWAKRCLA
                     FADAEDGHPERAADRYLEAFGEACGERRESASWAATMAALGREAVEALLDAGRADDAGA
                     VLDGLRPGVRERGRFRLLRARVLLAQGDAAAAREIFDGGFEVEDLREGDESLGETWYAI
                     QARLLAGEGPVTEEIRVRARAQALPRPYDFRMRPAP"
     gene            38017..38598
                     /locus_tag="AS857_RS08520"
     CDS             38017..38598
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825699.1"
                     /locus_tag="AS857_RS08520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_058042519.1"
                     /transl_table=11
                     /translation="MARTKEFDPDAALQSAVELFWRRGYEATSMADLVAHLGIARASLY
                     ATFGSKHELYLKALQRYSEQHSPRIAEELSRPGPALPAVRGLVTRFAGEAADDELRRGC
                     FVTNTAVELAPHDPAAARGVEESWLALEAALTAALTRAQEQGELPAGRDPVALARMLLV
                     LMQGMRVVGKAVPGRARLRDAAAQALALLE"
     gene            38699..39460
                     /locus_tag="AS857_RS08525"
     CDS             38699..39460
                     /EC_number="1.1.1.47"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-122). E-value: 1.2e-10. Score:
                     33.6. Matches aSDomain:
                     nrpspksdomains_AS857_RS08525_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008408995.1"
                     /locus_tag="AS857_RS08525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_058042520.1"
                     /sec_met_domain="adh_short (E-value: 2.3e-32, bitscore:
                     109.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.1e-30, bitscore:
                     104.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTARFTGRTVLVTGGGTGIGQAIALAFAREGARVVVAGRREEPLK
                     ETVAFVEAEGGEAVAVTADVTRAEDVRALVEQTVARFGSLDVAVNNVGLAVPPAKVADV
                     PEEDFDRIVGTNLKGVWLSMKYEIGHMRANGGGAIVNIASNVGAHRRKPGFGAYTATKA
                     AVSALTRNAALDHIGEGVRINAVSPGPVETPMSSRPGESSLDKAERMSREVPAGRAGTP
                     DEIASAVLHLASDEAGYTVGADLVLDGGVTA"
     CDS_motif       38723..38818
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08525_0001"
                     /evalue="5.60E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="AS857_RS08525"
                     /protein_end="40"
                     /protein_start="8"
                     /score="22.2"
                     /tool="antismash"
                     /translation="TVLVTGGGTGIGQAIALAFAREGARVVVAGRR"
     aSDomain        38723..39064
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08525_PKS_KR.1"
                     /evalue="1.20E-10"
                     /label="AS857_RS08525_PKS_KR.1"
                     /locus_tag="AS857_RS08525"
                     /protein_end="122"
                     /protein_start="8"
                     /score="33.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TVLVTGGGTGIGQAIALAFAREGARVVVAGRREEPLKETVAFVEA
                     EGGEAVAVTADVTRAEDVRALVEQTVARFGSLDVAVNNVGLAVPPAKVADVPEEDFDRI
                     VGTNLKGVWL"
     gene            complement(39450..40862)
                     /locus_tag="AS857_RS08530"
     CDS             complement(39450..40862)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038: phenylalanine-specific permease"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942163.1"
                     /locus_tag="AS857_RS08530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid permease"
                     /protein_id="WP_058042521.1"
                     /transl_table=11
                     /translation="MHDTDGTHTRRFGLPTATALVMGNIIGGGIFLLPASVAPFGTVSL
                     LAFGVLTVGAIALALVFGRLAERHPRTGGPYVYAREAFGDFAGFLSAWSFWTMTWVSNA
                     ALAVAGVGYLHVMTGKGSMAGDLAMALAMLWLPTLANLAGTRWVGAVQMISTVMKFVPL
                     LFVAVVGLFFFDPDKLGSFTTSDGNWTGGLTASAAILLYSYVGVESAAMSAGEVRDPER
                     NVGRASVLGTVGAALVYLLGTVSVFGTVEHDKLVESTAPFSDAVDVMFGGHWGGTLIAL
                     CAVISIVGALNGWTLMSAQAPYAAAKDGLFPAAFGKKKRGVPTFGVLAAAVLASLLTIV
                     NYTSGVGGVFEILVLITTFSATVPYLLAAAAQVYFLLTGQRDKVRTGRFVRDMALALGA
                     FAFSFWLVAGAGYAAVYQGVLFLFAGILVYVWLTARRTTAQAGAQDGAAQSAAPERAGT
                     AERAEQAEAVRP"
     gene            41233..42441
                     /locus_tag="AS857_RS08535"
     CDS             41233..42441
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (42-187). E-value:
                     1.2e-08. Score: 26.4. Matches aSDomain:
                     nrpspksdomains_AS857_RS08535_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942176.1"
                     /locus_tag="AS857_RS08535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_058042522.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 4.6e-07, bitscore:
                     26.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQVSFPALPAGTAPERGLPVLPELAARLAQAARDSAPEPVGGGDA
                     LRAAACGYWARRGLPTAPEHVLAAPGAQPLLLAVLAGAGGDVLLTRPCAAWYPPLARLA
                     GRPTYHVPVPAECGGVPDPFALLETVRRIRAEGGRPRVLVLSVADDPTGSVTPPELLHE
                     VCEAAVGEELTVVSDETWRDMRHDPGGTVFFGPAEMWPDHVVVLTDLAGGLFPTAWPAA
                     VARFPAGGRGPVLRARVTSALAAVRAELAPPVAAAAAYALDEPGPVRARAADAVRIYGA
                     LARAAREHLTAAGVLSRPSQAGPYLYADLGELRAALADRAITDSVELEAHLSTALGRPV
                     PGGHRFGDDPDALRVRISTPPLLGATDEERQRALDAPDPLAAPGVAAALTSFGSAFGRL
                     AGG"
     aSDomain        41359..41793
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08535_Aminotran_1_2.1"
                     /evalue="1.20E-08"
                     /label="AS857_RS08535_Aminotran_1_2.1"
                     /locus_tag="AS857_RS08535"
                     /protein_end="187"
                     /protein_start="42"
                     /score="26.4"
                     /tool="antismash"
                     /translation="GDALRAAACGYWARRGLPTAPEHVLAAPGAQPLLLAVLAGAGGDV
                     LLTRPCAAWYPPLARLAGRPTYHVPVPAECGGVPDPFALLETVRRIRAEGGRPRVLVLS
                     VADDPTGSVTPPELLHEVCEAAVGEELTVVSDETWRDMRHD"
     gene            42531..43628
                     /locus_tag="AS857_RS08540"
     CDS             42531..43628
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019521747.1"
                     /locus_tag="AS857_RS08540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_107105539.1"
                     /transl_table=11
                     /translation="MTEQTERPLAEPRPLGEIRIWPKSFADRLTAPLPGVRALARLARE
                     GRLRPGAEALREIAALPVEPGPLPVTDAATAAVTWAGHASWVVRIGGLTVLTDPVWSRR
                     ILGTPPRLTPVGVRWEDLPPVDAVVISHNHYDHLDAPTLKRLPRHTPLLLPAGLARWAR
                     RRRFTHVTELDWWEAVELPGPAGPVRFDFVPAHHWSKRTLTDTCRSLWGGWVMTAPGGQ
                     RVYFAGDTGYGHWFERIGRRYGGIDLALLPIGAYDPRWMLGTVHTDPEEAVAACQDLGA
                     RAMAPMHWSTFILSAEPPLEPLRRVRAAWEATGRPREDLWDLPVGGSRTLPGWSGSAPS
                     SRTGPLPLALPGSEPAGGAHGGAGT"
     gene            complement(43637..44170)
                     /locus_tag="AS857_RS08545"
     CDS             complement(43637..44170)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942169.1"
                     /locus_tag="AS857_RS08545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_058042523.1"
                     /transl_table=11
                     /translation="MASPLTLLTPRLTLRRWRADDVEPMAAVNADPEVMRWTGDGSVLD
                     RERTAAAVAAWEQGWDEHGVGLFAVEVRRSRRLAGFAGLSVPAELPELRPAVEVGWRLG
                     RPFWDDGLATEAARAVLDFAFRDRGLARVVGVHRTGHEAPAAVMRKLGMRHDRKTTHPE
                     YGVPLCVHVIEARP"
     gene            complement(44265..44837)
                     /locus_tag="AS857_RS08550"
     CDS             complement(44265..44837)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004941068.1"
                     /locus_tag="AS857_RS08550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR03086 family metal-binding protein"
                     /protein_id="WP_058042524.1"
                     /transl_table=11
                     /translation="MTDATLLNRHREALALFTERVHAVRPGQWDEPTPCTEWSVRDLVN
                     HLAVEQLWVPPLLEGRSIDDVGDALDGDRLGDDPVAVWDAAEAAAREAFAAPGALERTV
                     ELSSGPSDTRGYCSQMTADAVVHAWDLSRAIGADERLPKPLVELTRREVEPYIDSLAGT
                     GLFAEPVEPPPGADAQTVLLAQLGRRV"
     gene            45003..46520
                     /locus_tag="AS857_RS08555"
     CDS             45003..46520
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006602118.1"
                     /locus_tag="AS857_RS08555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional phosphatase PAP2/diacylglycerol
                     kinase family protein"
                     /protein_id="WP_058042525.1"
                     /transl_table=11
                     /translation="MRKIVSSWDRAAFLAVAARHWPGGDRVLPRLSRSADHGLLWFGVA
                     AGAALAGGRPARRAALRGVASLAVASATVNTVGKRSVRRLRPVLDVVPVVRQLSRQPFT
                     TSFPSGHSASAVAFTTGIALENPAWGLALAPLAASVCFSRVYTGVHYPGDVLAGAALGA
                     GAAFAVRGIAPTRAQLAPPARPRADAPALARGEGLVVVVNAGSGQRAAGVRTDPVQEVR
                     SALPLAEVTGYGQDGAGEGGDLGKVLESAALRARELDGALGVFGGDGTVNAAAVVARRH
                     RLPLAVLPGGTYNHFAYDLGIESLGDACRAVEAGEAVAVDMVRMCAGGGEEAGWFLNTF
                     SIGAYPELVRVRERWAPRVGAWPAGVLAAVHVLRTARPLRLEVDGRRRRLWMLFAGNCT
                     YRGLGLAPVRRHDLADGVLDVRTVSGGPLARTRLLAAALGGGLKHSPVLRTARVRSLRI
                     SGIRRGTHLAYDGEIAAAPGELTLRKENEALVVYRLPAEWDLRGRGV"
     gene            46585..47397
                     /locus_tag="AS857_RS08560"
     CDS             46585..47397
                     /NRPS_PKS="Domain: oMT (41-139). E-value: 3.2e-08. Score:
                     23.9. Matches aSDomain: nrpspksdomains_AS857_RS08560_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003981768.1"
                     /locus_tag="AS857_RS08560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="methyltransferase domain-containing protein"
                     /protein_id="WP_058042526.1"
                     /sec_met_domain="PCMT (E-value: 7.6e-07, bitscore: 26.2,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADDETTVYTHGHHESVLRSHAWRTAANSAAYLLPELEPHLEILD
                     VGCGPGTITADLAALVPQGRVAGLDAAEEVLGAARATAAARGLTNTDFTVGDVRALDFP
                     DGSFDVVHAHQVLQHVGDPVGAMGEMRRVCRPGGLVAVRDADYSAMTWYPAVPGLDDWQ
                     DLYRRVARTAGGEPDAGRRLLSWARRAGFTRVSATASAWCYATEEERSWWSGLWAARTT
                     ASAYARLAVDGGHADRAGLDRIAAAWREWGRHEDAWFAVLNGELLCRA"
     aSDomain        46708..47001
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08560_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.20E-08"
                     /label="AS857_RS08560_oMT.1"
                     /locus_tag="AS857_RS08560"
                     /protein_end="139"
                     /protein_start="41"
                     /score="23.9"
                     /tool="antismash"
                     /translation="EILDVGCGPGTITADLAALVPQGRVAGLDAAEEVLGAARATAAAR
                     GLTNTDFTVGDVRALDFPDGSFDVVHAHQVLQHVGDPVGAMGEMRRVCRPGGL"
     gene            47440..47790
                     /locus_tag="AS857_RS08565"
     CDS             47440..47790
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942178.1"
                     /locus_tag="AS857_RS08565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glyoxalase/bleomycin resistance/dioxygenase
                     family protein"
                     /protein_id="WP_058042527.1"
                     /transl_table=11
                     /translation="MNILGTSLRVCVDDLDHAIGVYERLTGAEALRFHRGGVAVAAVGC
                     FFLMSGPEKELSILRKITATIAVTDVEEALGDLEAVGAQIIAGPVPTPIGRNLVARHPD
                     GSVFEYVDRKQG"
ORIGIN
        1 tgcacggtga ccgcgcggta ggactcgggg acggtcaggg ctgcgaagtc ctcggacgtg
       61 gtgtccggcg cgaggatcgc gtcgagtatc tggttcacgg tattgcctcc ggcgaagcac
      121 gtcgggaaac ggcttgaggg aacgtcgggg gtggtgcaga gggtggagca gaggcggtgc
      181 cgtcggttcg gcggtggtgc ggggcggtgc cttgtgcggt gatgcggcgc cggtgggcgc
      241 gctgggaaat gcctgtgacg caggcgtccg ggcgcacagc gttcttgtgg ggacagccgg
      301 cgcacgacgg ttgtcgtctg cgcgccggcc gcccggacac cgacaacgta tggcaccgcg
      361 tgccacacga caagacactc ggtgccaaca atttctctca gatgtcatcc ggaaggcacg
      421 tatgagcaac gaaggccgcc ccgagggggc ggccttcgtc agtaaatgag agtttttgtt
      481 ctacttcgtc ttgagcgcct tctcgatcgc ccgcatgacc tcgcccagcg gcgcgtccgt
      541 ccgggccacg gtcaccagga cctcgccctc ggtccgcgcc gaggcggccg ggccgtcctc
      601 cgcccgggcg cgcccggccc cgatgcccgt gccgaaggtc tcccgcacga tcgcgaacgc
      661 gtggtcgagc tgggtctcca cgtcgccctg gccgccgccg cgcagccagc gccgcagcac
      721 gtggttgtgc gcggtgacga cggccgaggc ggcgacctcg gcgagcagcg ggtcgtcgtc
      781 gccgacgtgg tgggcgctct cgtcgaagtg gccgaggagg tagcgggtga agagccgctc
      841 gtagcgggcc acggaggcga tctcgcgctc gcgcagggcc ggcacctcgc gggtcaggcg
      901 gtagcgctcc acggagacgg cgggggaggc cgcgtacatc cgcatgacct ccttgatgcc
      961 ccggcagacg gtgtcgaggg ggttctcgtg cggcggggcc gcgtccagca cccccgcggc
     1021 ccgcaccagg gtgtcgtcgt ggtcggggaa gatggcctct tccttggagc ggaagtggcg
     1081 gaagaacgtc cggcgggcga cgccggccgc ggccgcgatc tcgtcgacgg tcgtcgcctc
     1141 gtagcccttc gtcgcgaaca actccatcgc ggccgcggcg agtttgcggc gcatggtgag
     1201 ccgctgggcg gcggcgcggc ggctgccggc gctctcggtg tcggggtgcg ggtctctggt
     1261 ctcgcggggt acttctccgg ccgtgcgcgg ggtgcggacg gccttggcgg gctggggcat
     1321 gtggggaacg taacacgcgt ccgtacgggc gtgccggggc ggaccgtccc cgggttcgag
     1381 cagtccgccc cagcccacgt cgcgctcgcg cgcggtccgg tcaggccttc gcatactcgc
     1441 ggaagccgcg gcccgtcttg cgccccaggc agcccgccgc caccaggtgc tccagcaggg
     1501 gcgccggagc gagcccgggg tcgcggaact cgcggtgcag gaccttctcg atggccaggg
     1561 acacgtccag ccccacgacg tcgagcagct cgaagggccc catcggatag ccgccgccga
     1621 gcttcatggc cgcgtcgatg tcgtccgggc tcgcgtagtg ctcctgcacc atcttgaccg
     1681 cgttgttcag gtacgggaac agcagggcgt tgacgatgaa cccggcccgg tcgccgcagt
     1741 ccacggcgtg cttgcgcacc ttcgcgcaga ccgcgcggac cgtggcgtgc acgtcgtccg
     1801 cggtcaggac cgtgcggacc acctccacca gcttcatcgc cggcgccggg ttgaagaagt
     1861 gcatcccgag gacgcgctcc gggcgggccg agtcggcggc cagccgggtc acggacaggg
     1921 cgttggtgcc cgtcgccagg atcgtctccg ggcgcacgat cgcgtccagg gcggtgaaca
     1981 cctcgtgctt gacggcgtag tcctcgggca cgacctcgat caccaggtcg gcgccggccg
     2041 cggcctgcag gtccgtggcc gtgcggaagc gggcgagcgc ggcccgccgc tcgtcctccg
     2101 tgatgcgctc gcggcgcacc gcgcgggcgg tggcggtttc cagcgcgcgg acggcgtgcg
     2161 ccgccgcggc ctcggagacg tcgatcccga cgacctcgcg gccggcccgg acgaggactt
     2221 cggcgatgcc ggtgcccatg gtgccgaggc cgacgacggc gacggtcctc aggggggagg
     2281 gggaggaggg ggacggctca ggggtggacg tacggtccat cgcgagactc cagaaggtgt
     2341 tccccgggcg cggggatgca tcggtcggtt gccggtgcag gcgggcggcc ccggcgggcc
     2401 gcggcggctg cgggattttc cgggtgcggt atttccgggt acgtacgggt aaggggcgac
     2461 cacggaaagg gagttgtgcg accggcaggc cctgtcccgg ggccgtgccg tactcgacgg
     2521 gccgaaccga cgaaccgacg tcgaaagcag cgggcggctg cgtcaccagg ccgcccgagc
     2581 gggggtaccg ctcttgccgg gagattaact cacgggtaac caagagcgcc aggggcgggg
     2641 ccggcgactt acgatgtggc gcaggccact cggggaggag aagcgggcag tgacaggagc
     2701 cgagagggca gaagaggaat tccgtgcgct ggtgaaacgg gtgcgggccg aactgggcac
     2761 gtcggccgag ttctcggagt tcgagcggct cctcgcgctc gtccgctcgc gcgagggcgg
     2821 accccccgcc cggcgcgcgc ggcgcgacga gctcgccggg atgctggtcg cccccgaaca
     2881 accgctgtgg gcccgcgaga tcgccgcctt cgtcctgggg gcggagggcg accggcgggc
     2941 cttcgagacg ctgatcctgc tcctcaacta ccgcgagccg gtgcgctgcg ccaccgccgc
     3001 cttcgtcctc gcccgcctcg gcgacccccg caccgcccgc gcggccgcgg ccctcgccac
     3061 caacccgctg cgcaccgcct acgccctgca ccccgtccgc ctgctgaccg agctgcgcgc
     3121 ccccgagtcc gtccccgccc tgctggccac gctcgaacgg ctgctggcgg cccgcgacca
     3181 ctgctggccg atagcccgcg cctgcgtgga gggcctgggc gccctggggg accggcgggc
     3241 ggaggacgcc ctggtcgcgg cccgcgaaca cgaccgcctc cgggcggcgg cacaggaggc
     3301 gctggagcgg ctcatgtgac gggcggggcc gacgccccgg cggcgtccct cacagcaggg
     3361 tgagctgagt cgcctgcgga ggcgtcgggc ccgggtcctg cggcggtgcc gcggggatac
     3421 ggcggtggcg gccggggccc gtcgggccta tgccgaattc ggttgcgtat tcgtggactt
     3481 gccgggtgat gcgccgctgg taccacttcg gggcgtaggc gccgtccgcg tacatcgtct
     3541 cgtagcgccg caccaggtgc gggtggtggc gggccagcca ggccgtgaac cactcgcggg
     3601 cgcccggccg caggtgcagc acgagcgggg tgaccgaggt ggcgccggag gcggcgacgg
     3661 cgcgcaccgt cgcccgcagc tgctcggggg agtcgccgag gaaggggatc accggcgcca
     3721 tcagcacccc gcaggggatg ccgtgcccgg tgagcgtccg gacggcgtcg agccggcgcg
     3781 cgggcgaggg ggtgccgggc tcgaccgtgc gccacagctc gtggtcgagg aagccgacgg
     3841 acatcgacac cccgacgtcg gtgacggcgg cggcctcgcg cagcagctcc aggtcgcgca
     3901 ggatcagcgt ccccttggtg agcaccgaga acgggttcgc gcgctcgcgc agggcggaga
     3961 tgatgccggg catcaggcgg tagcggccct cggcgcgctg gtagcagtcg acgttggtgc
     4021 ccatggcgat gtgctcgccg cgccagcgcg gggccgccag ctcgcggcgg agcgcctcgg
     4081 gggcgttgac cttgacgacg atctgggtgt cgaagccgag gccggtgtcc aggtcgaggt
     4141 agccgtgcgt cttgcgggcg aagcagtaca cgcacgcgtg cgtgcagcca cggtaggggt
     4201 tcaccgtcca ctcgaagggc atccgggagg cgcccggcac ccggttgacg atcgtcttcg
     4261 cccggacctc gtggaaggtg atcccgcgga actcgggggt gtcgagggtg cgcgtcacca
     4321 cgtccgtgcc gaagagcgcg cccgggccgt cgtcggcgcc gtcgccgccg aggttggacc
     4381 agcgcatggc acctccttcg catcattcgt tcgaacgttc gatccctccc gtcgagatta
     4441 gaacatatgt tcgcgcgggg cgagggggcc cggatttggg cgggtgtggc gttggtggtt
     4501 ggctgtgccg cgaagcaggt acggcaagca cagctttttc acatgtcccg gagggcagcc
     4561 atgggccagg tcgaggccac gacggagcgg atcatcgcgg cggacccgga ggaggtgttc
     4621 gacgcgctgg cggactacac cggcacccgg gccaagctgc tgcccgagca cttcagcgag
     4681 tacgaggtgc gcgagggcgg ggacggcgag ggcaccctcg tgcactggaa gctccaggcc
     4741 accagcaagc gcgtccgcga ctgcctgctg gaggtcgccg agcccaccac cgggcagctg
     4801 gtcgagaagg accgcaactc ctccatggtc accacctgga ccgtcacccc ggccggcgag
     4861 ggcagggcgc gggtcgtcgt cagcaccgtg tggaacggcg ccggcggcat cggcggcttc
     4921 ttcgagcgca ccttcgcccc caagggcctc ggccgcatct acgacgccgt cctcgacaag
     4981 ctggccgcgg agaccgagaa gtaggcggcg cacggccgag aggcagtcgg tggaagcccg
     5041 gaccggtcgc ggtccgggct tcaccgtttc gggtggtttc ccccggcgtc gcagggggcc
     5101 gccgtatgcc tccgaccggc gcaaaagccc caccgatggt ctctcgggtc aatcccctcg
     5161 gttgcccgcc gttgtcgcga aatgcgagaa aagggcggcg atagcaggtg ctacgagggg
     5221 agcggcacgt gggtgggacc actttggtac agagcgacgg gccgccggtg cccgtcctgc
     5281 tcgcacccga ggccgccccc gcacctccgg cgccccccga accccccacc gtccggggac
     5341 ggttgggcgt ggtcctcgcc ggcctgctgc tcgcactgtt cctcgccgcg atcgaccaga
     5401 ccgtcgtcgc caccgcgctc ccggccatcg ccggagacct gcacggcgcc ggccgggcca
     5461 cctggatcat cacggcctac ctgctcggct ccgccgtcgc cgttcccgtg cacggccggc
     5521 tcggcgaaac cgccggccgc aagggcgtct tcgccttcgc cgtcgtcctc ctcgtcgccg
     5581 gctccgccct cgcggcccgg gcgcagacca tggaccagct cctcgccttc cgcgccctcc
     5641 agggcatcgg cggcggcggc gtcctggccg ccgtccacgc gatcatcgcc gacctgaccc
     5701 ccgcccgcga gcggcgccgc cgcctcggcg cggccgccgc cgtcctcgca ctcgcctccc
     5761 tcgccggacc gccgctcggc ggcctcctca ccgaccacgc ctcctggcgc tggtgcttcc
     5821 acctcaacgt ccccctcggc ctgctcgccc tcctcgcggt caccttcggg ctgcggctcc
     5881 cccggcccgc gcaccgggcg cgcttcgaca ccctcggcgc cctgctcctc gtcgccttct
     5941 cggtctgcgc cgtcctgctg gccgaccggg ccgggaccgc ccccgcctgg cacgcgcgcg
     6001 ttgtcctcgg cctcgccgcc gccaccctcg gcaccgccct gctcttcatc gtcgtcgagc
     6061 acctcgccgc cgaccccctc gtcccgcccc gcctcctccg cgaccgcacc ttcctcgtct
     6121 gcgccgccct cggcgcgggc accggcgcgg ccctcttcgg cgccgtcggc tgtctgccca
     6181 ccttcctgca gatggccgac ggcgcaggcg ccgtccgggc ggggctgctg ctcctgcccc
     6241 tcacagccgg cgccgtcctc ggctccctcc tcagcgggcg gtacgcccgg cgcaccggcc
     6301 gatgccgcct cttcgccgcc gccggctgcg ccgcggccgc cgccggtgcg tacgcgctct
     6361 cccgcctcgg caccggcacc acctggcccg cctacgccct cgcgacggcg gccctcggcg
     6421 ccggcaccgg gctcgccctg cccgccctcg cccgcgccgt gcgcaactcc gtgcccgccg
     6481 cggacctcgc cgccgccggc agcgccggca cgtacctgcg gcagctgggc ggcgcgctcg
     6541 ccgtggcctc cctcggcgcc ctcctcgccc accgcctcgc cggcgggccg ggccgcagca
     6601 gcgggccgtc cgccccgcac gcgctcaccc cgcggctgct ccgcgccctg cccgccgagc
     6661 tccgcggcgg ctacgtgcgc gcctacgcgg acgccatgcc gcggatcttc ctgtacctcg
     6721 tacccgtcct cgtcctgggc cttttactcg ccttcctgct gaaggagaaa ccgccggtgt
     6781 cccaaaacct cgccgaagcc cccgtcatcc cctccgcgcg gaccgcaccg cccgaggagg
     6841 aacccccctt cgtcccgggc atccccgtca ccggagtcgt ccagcaccac gacggcacca
     6901 ccgtgccccg cgccgccctc accctgatcg acagcggggg acggcagatc gggcgcgggg
     6961 ccaccggcga ggacgggcgg tacgccctca gcacgcccgg caccggctcc tacgtcctca
     7021 tcgcggccgc gggcggacac cagccccagg ccgtcaccgt caccgtcggc gaacgccccg
     7081 tcgagctcga cgtggtgctc ggcggcgccg gccgcctcgc cgggaccgtc ctcaccgccg
     7141 acggctcgcc cgtgcgggac gcgctcgtca ccctcaccaa cgtgcacggc gaggtcgtcg
     7201 cctccacccg caccgggcgc gacggcggct acgacatcac cgaactcgtc gccggcgagt
     7261 acacgctggc cggcagcgcc cccgtcttcc ggcccgccgc gctgccggtg accgtccagt
     7321 cctgccgcga gacccgccag gacatcgagc tcgccggcgg ggccgtcctg cgcggcgtcg
     7381 tccgggcggg cggcggccgg ctggtcgagg acgcccgcgt caccctcctg gacgccgcgg
     7441 gcaacgtcgt cgacaccgcc accaccggcc ccgacgggtc cttccggttc gtggacctct
     7501 cggcgggcga gtacaccgtc atcgccgcgg ggtacccgcc ggtggctacg gtgctccagg
     7561 tcgcaggcgg aggccgcacg gaacgcgacc tccaactcgg ccacgcggac tagccgtccg
     7621 gctgggttcg gggcgccccc gggcgcgggg tccggcttcc gccgggccct acgccggggg
     7681 gcggcgccgt tacggcggga ggtttcccgg ctacgccgga tgccctggct cgccccgcgc
     7741 gcggcggcgg gctgccccgg ccgtcacggg gacacctgcc tcggcaggaa tgacctcccg
     7801 ccggtgccgg tggccgcgga ttccgccgga ctctcgccgt ggtggcgcct cgccgtcgcg
     7861 gcgggaggtt ttcccggctt cgccggggga gcgggctcag gcgcaggccc tgtgcatgac
     7921 ggcagtcatc cccctcccgc cgccgcggcg ttcggccacg acggtgaggg tccggcggaa
     7981 tcggggcctg ccggaccggt gggtgtggat tccgccggac cctcgccgtg gtggtgtttc
     8041 gccgttgcgg cggctgcggc gcgcaggcga cgtcccctac ggcaccggcc acgttgcgta
     8101 ccggcgcatt ccgtacagca gcgggggctc ctccgcgctc cgcgtggtgg tcgtgcggac
     8161 tatttcgccg atgatcacgg tgtggtcgcc ggcgggggtc aggcggtgga cgcggcattc
     8221 ggccgccgtg tgggcgtcct ccgggaggag gggcaggccc gtggccgggg agggctgcca
     8281 ggggacggcc gagaagcggc ccgcgtcgcg gtgggcgaag gcctccgcgg cgcggcgtcc
     8341 cgccccgtgc aggaggttga cggcgaacca gccgcgcccg gcgagcaccg gcagggtgct
     8401 gcccttggcg gaggcgcaca cgagcagcag cggcgggtcg agggacacgc cgcaccacgc
     8461 cgtgcacgcg aagccgtacg gggtgccgag gccgtcgtcc gtggtgacca cggccacccc
     8521 gccgggatgg ctcgccatca gggcgcggta gctgtcgggg tcgacggggg agagcgcggt
     8581 ggtcatggcg gggtccttcg ggtggaggtg cggttgccga gggccgcggt gacgccgatg
     8641 ctgcccaggc acagcaccgt caccaccccg gcgaagacgc cggccgccgt catgagcgtg
     8701 ccctcggcca gcagcacggc cacgccgacg acgggcacgg tcaggcccag gtacgcggcg
     8761 acgaagtagc cggagaccag ctccgagacg cggtcgggcg cggcctggga cgtcaccagc
     8821 gccaggccgg acttgaagga cgtgcccgcg cccgccccgc ccagcacgga gccgcacagg
     8881 aagacgggca gcgacgcggc ggacaggccg gtgacgatga gggcgagccc gagcgggacg
     8941 gcggtcatgc cggcgaccag cccggcgcgc ggcgtcatcc gccccgcgag gagctgggcc
     9001 gcccccgccg agccgaaggc gctgaaggcc accaggccga cggcgaggtg gctgtggttg
     9061 tgcagccctt gcacgaggaa gttgcccgcc agcgcggcca gcaggcccag cagcgcgaac
     9121 gaggcgaaga cggcgaccgc cgcggcggcg aacggccgcc gcacggcggg cggcacgccg
     9181 atccgctgcg ggcggatccc gcccccgcgt gccacgaccc gctcgggcag cagcacgagc
     9241 gccgcgcccg gcagcagcag gacgatcagg acggtgtacg gcagcacctc gggcgagggc
     9301 gcgtactcca cgaggacgcc cgacagcagc gccccgctgc cgagcccggc catgttggtg
     9361 accgaggcga tgagggcggc ccgcggcggg gaggggtgca gttctctcag gtacgcggtg
     9421 gcggcgcccg tcgtcaggcc caccgagacg ccggagagca gccgcccggc gaacagcccc
     9481 ggcagggtgg gcagggcgat gaagacgacg ctgctcgccg cggccacgac cagcgccggg
     9541 acgagcgtgg cgcgccgccc gatcttgtcc gacagcccgc cgaacagcag cagggcggcc
     9601 acgatgccca ccgcgtaggc cgcgaagacc agggcgacga ccggcgggga caggtgcagc
     9661 cgctgcacgt acagggcgta gacgggcgtg ggcagggtgc cgccggccat caccacgaac
     9721 agcacgtacg tgacggtggg gacggcggta cgcggtacgg cgggcagggc gggggccggg
     9781 gcccccgctg cggcgagccg ccgctgtcca ttggccctca ccagtcgaag gccgtcgcgt
     9841 cgtacaggtt cacgccgagc gcggccttgc ccaggtactc caggcactcc tccggtttgg
     9901 cgggcatcac ggaggcaaag gacgcctcgc gcaccagccg ttccagcggc tgcgaccggc
     9961 tcacggccac cgagccgcag atccgtacgg cgtcctgcgc gagggcgggc ccggtctcgc
    10021 cgacgacgta cttcgcggcg tgcaccgcgg cgttggcctc cgcgctgccg cgcgcagcgt
    10081 ccacgcgcgc accggcctcg gcgaccaggg cccgggcggc gctcagccgc gcggacatcc
    10141 ggccgagctc gcgctgcagc accggcgacg cggcgcgccg gggcgatgcg gccacgtggt
    10201 ccgtggtgaa gcggaggatc gcctcggcga tgcccaggta ggcgccggtg tacccggcga
    10261 tcatccagtg gggttcgcgc accagcttgt acagggacat cccctcgact ccgaggaaga
    10321 gccgggagcg cggcacggtc accgcgtcca gggtcatgcc cgcggtgctg gtgccgtaca
    10381 tggcggacag gctgtgcacc tctccgaagc ccacaccgcg gtcgtcggcg gcgaccacga
    10441 agtgcgagac ctcgccgctg ccttcggtgc cctcggcgcg ggcggcgacc acgtagtagt
    10501 cggcgactcc cgccagcgac acgaaggact tctcgccggt gatgacgtac ccgccgtcct
    10561 cggtgcggcg gtaggaggtg cgcacgccgc ggagcttggc gccgctgccg gcctcggagg
    10621 tggcggaggc gaacagcttc cgcccgtgga ccacctcgtc gaagagccag gaccggaagg
    10681 cctccgccgc gggcggcagg ggcgtgccgg cggactcgca cagggagccg atcgcgacgt
    10741 tgtgcatgtt gaagccgagg gcggcggcgc cgttgtgcgc gcccagcacg gcgagcaccc
    10801 gggagtacgc ggcgaagccg agcccggccc cgccggcctc gcgcggcacg agcaggccga
    10861 gcagcccggc ctcgcgcagg acgcggtagg tctcgtggcc ggtggagcgg cccgcgtcca
    10921 cctcggcggc gaacggggcg agggccgccc cggtcgcctc ggcgacgtcg agcagttcgt
    10981 cgaattcggc gggcagcagc tcggtgggca gggacatggc catgaggggc ctttcggaaa
    11041 tcgggttccc ggctcgggaa tcggttcgcg aatcagtttt cgacggggag cccgaattca
    11101 cgggcgaccc cgatgcgcag caggtcgttg gggcctgcat aagtgagcgc cgccatgggg
    11161 ctgtgcagat cggcggggag ttcggaatcg gcgatgaagg cccgtacgcc cgacagcgcg
    11221 gtggcgtgct cggtcagccg tacgtagtcc tcggagacgg agatcttggt cagggcggcc
    11281 tcggccgaca gccggcgggt gggcgtaccc gcgtcgagcc gcgccgccat ggcgtacagc
    11341 agcgtgcggg agcggtgcag gacgagcgcc atgtcgctga tgcgggcggc cacttggtgg
    11401 ctggagccca tgcggcggcc gaagtggccg cgctcggaag cccagtccgt caggcgctgc
    11461 agggtgcggc gcatcgggcc gagggcgtag ccgagcagca gggcccgctc ccaggtggtg
    11521 gtggaggaga ggatcgccag gcccgacccc tcgccgccca ccaggctgcc cgcgtccagg
    11581 cgtacgccgt cgaaggccag ctcgcccatc ggcacgccgg gcagcgcggt cttggcgaac
    11641 gcctcggcac gggtcacgcc cgcggtggcg acggggaaca ggaaggcgga cagggagaag
    11701 ggcgagcggc cctgctcggt gcgggcgaag acgagggcca ggtcggccac gggggcggcg
    11761 gtgatgaagg tcttggcgcc ctccagaacg tagccgtcgc cgtcgcgcgt ggcgcgggtg
    11821 tccatcgaca acgggtcgct gccgcccttg cgttcggtga gggcgtggca cagcagctcc
    11881 cgcccctcct ggatgcgggc gacggaccgc cacgcgccgg ccgggagcac ggcgcgcagc
    11941 ggatactcca tgccgaacac ctgggaggcc atggcgtaga cgacgccggg gtcggcgccg
    12001 gccaggccga tgccctcgat catggccagc gagcgggtga cgggcccggg ggcggcggcg
    12061 cccgcggacg ccccgggccc gggctccggg gcgtccagac aaagcacgcc gagcccggcg
    12121 agggcctccc actggtcgcg gaagcccttg ccggccagct gctccaccag gggcagcgcc
    12181 cggtcgcggt actcgtccac cacggcctcg gcccccgggg gaccggagcg cagcaggcga
    12241 tcggcggcgc tcacagtgtc tcctcgttct cccccagagc ctgaacggcc tgggaggtac
    12301 ccccatctcc gcctgcgcgg cgcagaggtg cgggcatcac ggtcgggtgc ggcccggtgg
    12361 ccgcgcatgc gtcgctcacc gggctactcc cgcccggagg tcctccagca cgctccacag
    12421 cgcctgcggg ctgcggaagt tggccgcgac gatctcggtg tccggcagca cgatgccggc
    12481 ctgcgcgtcg agcgcggcga cgatctgcat gatggacagg gagtccagca ggccctgttc
    12541 gagcagcggg gtgtcgggca ggagctgccg gggctcctcg ccgcgccccc aggtgatctt
    12601 gctgctgatc agggtgcaga gatcctctac ggtgttcacg ctcgggctcc ttctgtggcg
    12661 agtggtggac ggatcaggcg gtgtgcggcc cgtcggtgcg ggcggcgagc gcgcggcggt
    12721 cgaccttgcc gcgggcgttg acgggcaggg cggcggcggg gacgacgcgg tcgggcagca
    12781 tgcgcagcgg caggagcccg cgcagaccgg cgaggatccc ctcggcggtc tcctcggggg
    12841 aggtctcggc agcggccgcg gcccccgtcc cgcccccgtc gctctggacg tacgcccaga
    12901 tctcgccgtg gtgcgcgccg tccttggcga cgacggcggc ggcggtgacg ccgggcagtg
    12961 cgagcacggc gctctcgacg tcgagcaggt cgatgcggtg gccgcgccgc ttgacctggg
    13021 tgtcgccgcg gccgcgcagg aacacgcggc cgtcggcggc gatgcggccg atgtcgccgg
    13081 tggcgtaggc gcggcgggcg acgccgtcgc ggaagcgcac cgtgcgggtg gggtcggtga
    13141 gggtcccgtc ctgcaggtat ccctggaaga cggtggcacc ggcgacgtgg atctcgccgg
    13201 tgccgtcggt gggcaggccg tcctcgccga ggacgtcgac gacgtcgccg tcgacggccc
    13261 ggccgatggt ggcctcctgg tcggcggtcc agctggcggg cacccggctg tacgtgcaga
    13321 cgttggtctc cgtcggcccg tagaggttgt agagcggcac gtcgcccagg agccccagat
    13381 agcgctccag ggggcgcggg gcgaagggtt cgcccgcgaa ggccgccacg cgcagggaag
    13441 gcgggaagtc ctccgcgatg ccgccccgtt cgagcatgcc ctggtagagg gagggcaccg
    13501 cgtagaaggc ggtgatgcgc tgctcgtgga gccagccgac gacgtcgcgc gggaaggccc
    13561 gcaggacgtc gggcatgagg acggcgcagg cgcccgccgc ggccgtgctg aacaggtcga
    13621 aggtggtgag gtcgaaggtc agcgcggcct gcgagcccac gcggtcggtc tccgtcagcc
    13681 cgagctcggc ggcggcccac agcgcgaagt gggcgacgtt ggcgtgggag aggagcactc
    13741 ctttggggcg gccggtgctg ccggaggtga acaggacgta gccgccgctg ccggccggcg
    13801 cgggcagcgg ggcgggcttg tccgcggccg cgagcgtgcg cacccggttc aggccgtggt
    13861 ccagcgtgcc ctcgtccggc gcggggcccg ctcccgcctc ggcggcggcg cggcggcagc
    13921 cctccaggga gcggtccggg gcgagcagga gggagatccc ggcgccgcgc accatgtggg
    13981 ccgtgcggac gggcgggtcg gcgacgtcga gcggggccac gacggccccg gcccgcagcg
    14041 cggcgtagat gccgaggacg gcctcggagc ccttgggggc caggacgccc acccggtccc
    14101 cggtctccag gccggccgcg cggagctgcc gggccagatc gccgacggcg cggtccagtt
    14161 cggcgtaggt ccaggtgcgg cccccggcgg tgagggcggg acgggagggg tgccggcgcg
    14221 cggacgcggc gagcaggccg tccaggcgga cgtcgtcgag gtcgctcatg gtcgggtctc
    14281 ctggcgcggg ggcgggccgg cggggccggg ggcggtggcg aggaaggtct ggacggcgtc
    14341 gacgacgtcg tcgggccgtt cgaggtgcgg ggcgtggccg cagccggcca gctccaggcg
    14401 ctgcacgggc ccgccgaggg cgcgctcggc cgcgtcgaga tgggcgaagg tgccgtacgg
    14461 atcgctgtcg ccctggacga ggaggacggg ggcggtcgcg ccggccaggt cgccctcgat
    14521 gtcccagccg cggaaggcct cggagagcca cagcccgctc cagcggcgga acaccgtgag
    14581 cgggtcctgg tggtagaagg ccagctcctt ggcgagcggc ccggacgcgt gggcctcgcg
    14641 ggccgcggcg acgccgcgga gcgtctgcgg ctcggcgaac aggtgcgggg cgacggcgac
    14701 gacggcctcg accgggtgct cggccgcgtg cagcagcgcg atcgaggcgc cttcgctgtg
    14761 gccgacgagc acggggcggt ggacgccgag ccggtcgagc agctcgggga ggacctcgtg
    14821 ggcctcctcg tgcagggagc gcggggtgcg ctcctgcggg gccgggcccg aaccgccgtg
    14881 tccgtggcgg gagaagacca gggcccggcg gccggtggcc gccgccaggc gggccgggaa
    14941 gcgccgccac atggcgatgc agcccaggcc ttcgtggagg aggacgagcg gggcggcctc
    15001 ggagtcgcct tcgaggacgg tgtattcgac aggccctcgg gatatcgcaa tggtgggcat
    15061 gcagtgtcct tggtgtgagg gccggttgtc cgaaaggaag cgccggccgc cgccgggaac
    15121 cgataattgc gaaggtcaat ggtggcgtca actgctttat tttttcatgg ggttgaggca
    15181 accgtcccga cgggcgtggt aaaatgcggc aaaacttgga atatgcaatt cccccgcatg
    15241 ggcatggagg tttgcctcca tggcgcgccg gtgtcttccg ccactaccgg gcggggccgg
    15301 gagggaatgc cgccgccttt tccgcgaccc gccgaacgcc tgatcgagcg cggtgtccgg
    15361 cgcggcctcc gtcccgcatc cgtccgccgg acggccgagt cccgccgcaa gcccgttgcg
    15421 gcgaccgtgt caggacccgt gcagcggcct gccacctgcg gtaggactga ggcatggtga
    15481 agatcctgat ctccgcggac atggagggcg ccaccggtgt cacctggccg gccgacgtgc
    15541 tgcccggcgc ctcgcaatgg gaacggtgcc gccatctgtt cacctcggac gtgaatgcgg
    15601 ccgtcgcggg cttcttcgac ggcggtgccg acgaggtcct catcaacgaa gcgcactggg
    15661 ggatgcgcaa tctgctgctg gagaagctgg acgaccgggc ccagatgctc accggcaagc
    15721 acaagagcct gagcatggtc gagggcgtgc agcacggcga tgtcgacggc atcgccttcg
    15781 tgggctatca cacgggggcc ggcaccccgg gcgtcctcgc ccacacctac ctcgccaaca
    15841 ccatcaccgg cgtctgggtg gacggcgcgc gggcgagcga ggggttgctc aactccctcg
    15901 tcgtcgcgga atacggtgtt cccgtggtgt tggtgacggg cgacgacctg acctgtgcgg
    15961 acgccaaggg atatgcgccg ctggcccgtt cggtggccgt caaggactgc gtctcccgct
    16021 atgcggccgt ctgccgcacc cccgcgcgca cggccgcgga catccgcgcc gcggcccggg
    16081 aggcgacggc cctcgccgtg cggtacgagc ccgtcaccgg cggcggcccg ttcaccgtcg
    16141 acatcgagtt cgacgccgac cacctggccg gtgcggcgac ggtgatcccg ggcgtcgtgc
    16201 ccagcggcga gcgccgggtc tcgtacacca cggcgaccat gtacgacggc atccgctgct
    16261 tcaaggcggt cacgaccgtc gtgtcggccg cggtggagga gcagtatggc tgagatcacg
    16321 acggaagagg cggtagggcc ggagggggcg gaagtccggg tggacgagcg cgccctcgac
    16381 gaggcggtgt gcttcacctc cgacctgatc cgcatcgaca cgaccaaccg cggcgcgggc
    16441 gactgccggg agcggcccgc cgccgagtac gtggccgcgg cgctgagcgg ggccggcatc
    16501 gagccggtgc tgctggagaa ggagcccggc cggacgaacg tcgtcgcccg ggtgccgggc
    16561 accgatccgg gcgcccccgc gctgctcgtc cacggccacc tcgacgtggt ccccgccgac
    16621 cccgccgagt ggagcgtcca ccccttctcg ggcgagatcc gcgacggcgt ggtgtggggc
    16681 cgcggcgccg tcgacatgaa gaacaccgac gccatggtcc tgtcggtcgt acgggcctgg
    16741 gcgcgcaccg gcgcccggcc cccgtgcgac atcgtgctcg ccttcaccgc cgacgaggag
    16801 gaccgcgcct ggacgggcgc cgccttcctg gccgaggagc acccgggcct gttcgagggc
    16861 tgccggtacg cgatcggcga gtcgggcgcc tacaccttcc acgccgacgg cgggctgcgg
    16921 ctgtacccgg tggcggcggg ggagcggggc acggcctggc tcaagctcac ggcgcgcggc
    16981 agggcgggcc acggctcgaa acccaatcag gccaacgccg tcacccggct ggccgaggcg
    17041 ctggcccgga tcggcagaca ccgctggccg gtgcggctgt ccccggtcgt gagcgccgcc
    17101 ctcgtggaga tcgccgccct gcacggcatc gaggccgacc ccggcgcgcc gggcttcgac
    17161 gccgacgcgc tgctggagga gctgggctcc gcgtcccggc tcctggcccc gacggtccgc
    17221 aacagctcca acccgacgat gctggacgcg gggtacaagg tcaacgtgat cccgggggcc
    17281 gccgtcgggc acgtggacgg gcgcgtcgtg ccgggcggcg aggaggagtt ccgcaccacg
    17341 ctggaccggc tcaccgggcc gcacgtggag tgggagtact accagaaggg cacggcgctg
    17401 caggccccgc tcgccacccc gctgttctcc ctgatgcggg aggcgctcga gcgcttcgac
    17461 cccgacgggc acgcggtgcc gttctgcatg tccggcggca ccgacgccaa ccagttctcg
    17521 cgcctgggca tcgactgcta cgggttcgcc ccgctgaagc tgcccccggg cttcgactac
    17581 caggcgctgt tccacggcgt cgacgagcgg gtgccctgcg acgcgctgca cttcggggtg
    17641 cgggtgctcg accacttctt gatgaacgca gcctgatgaa cgcagcttga agaacacagc
    17701 ctgatgaacg cggcttgccg gacacggctt gacgaacaca gcgtgatgag cacggcctga
    17761 cgggccgttt cgaggaggcg taacagatca tggtgtccac ggcaccctac ggagcctggc
    17821 agtccccggt cggcgcggag ctcgccgcgt cggccggcgg cggacccgac ttcgtgggta
    17881 cggtcggcga cgagctgtgg tgggccgcac cacgcccggc ggaggagggc cgcttcaccc
    17941 tcgtgcggcg gcgggccggc ggggccgagg agacggtgct gcccgccccc tggaacgtgc
    18001 gcaaccgggt gctggagtac ggcggcctgc cgtgggcggc ggtggcccgc gcctccggcg
    18061 gcccgctggt ggtcttcacc cacttcgccg accagcggct ctacgccttc gagcccgacg
    18121 tccccggtgc cgtaccgcgg cccctgaccc cgctgtcgtc ggtgggcggc gggctgcgct
    18181 gggccgatcc ggtgctgctg cccggccgcg gcgaggtgtg gtgcgtgctg gaggagttca
    18241 ccggcgaggg gccgtgcgac gtgcgccggc tgctcacggc cgtcccgctg gacggctcgg
    18301 cggcgcggga ccgcggggcc gtccgggagc tgaccgacgg cgggaaccgc ttcgtcaccg
    18361 ggccgcggct ctccccggac ggccggcagg cggcctggat cgcctgggac cacccccgga
    18421 tgccctggga gggcaccgag ctgaagaccg ctcaggtctc cgcggacggc cggctggcgg
    18481 acgcccgtac ggtcatgggc gggcccgcgg agtccgtggc ccaggtggag tgggccgagg
    18541 acggctcgct ggtcgcggcg agcgaccgca ccggctggtg gaacctgtac cgcgtcgacc
    18601 cggcgacggg ggagagcacg gcgctgtgcc gccgcgagga ggagttcgcg gggccgctgt
    18661 ggcgcgtggg ggtgcgctgg ttcgcgccgc tgccgggagg gctcgtcgcc gcgctccacg
    18721 gccgcggcgc cgccgtcctc ggcgtcctcg acccccgcag cggggagatc gcggacgtcg
    18781 ccgggccgtg gaccgagtgg gcgccgaccc tggcggtgag cggcacccgc gccgtggggg
    18841 tcgccgcgag cccgcacagc gcgtacgagg tcgtcgagct cgacgtctgc acgggccggg
    18901 cccggaccgt cggcgcccgg cacaccgacc gcgtggaccc cgcctactac cccgagccgc
    18961 tgacgcgcac cttcggcggg ccggacgggc gcgaggtgca cgcccacctc cacccgccgc
    19021 gcaaccccgg ccacgccgcc ccggacgggg agctgccgcc gtacgcggtg tgggcgcacg
    19081 gcggccccac cgcccgcacg cccctcgtcc tcgacctggc cgtcgccttc ttcacctccc
    19141 gcggcatcgg cgtcgccgag gtgaactacg gcggctcgac cggctacggg cgcgcgtacc
    19201 gcgagcggct gcgcgggcag tggggcgtgg tggacgtcga ggactgcgcg gcggtggccg
    19261 cggcgctggc ccgcgagggc atcgccgacc cggcccggat cgcgatccgc ggcggcagcg
    19321 cgggcggctg gacggcggcg gcctcgctcg ccgccacctc gctctacgcc tgcggcacca
    19381 tcctctaccc ggtgctggac ccggaggcct ggacggcgga gggcggcacg cacgacttcg
    19441 agtcgcgcta cctggagtcg ctgatcggcc cccgggagga ggtgcccgag cgctaccggg
    19501 agcgctcgcc gctgcaccgg gcgagccgga tctccgcgcc cttcctgctg ctgcaggggc
    19561 tggccgaccc cgtctgcccg cccgcgcaga gcgagcggct gctggcggcg atggccgggc
    19621 gcggggtgcc gcacacctac atcgccttcg agggcgaggg ccacggcttc cgccgggccg
    19681 ccacggtcgt gcgcgcgctg gaggcggaac tgtccctgta cgcgcagacc ttcggggtcg
    19741 ccgcgccggg catggcggtc ctggagctcg tgacctgacg ggccggaacc tccgccccgc
    19801 aggggggtgg ccgccgggca gccgggggtc acccccctat aggcaagagc gtgaggttag
    19861 cctaacctaa gccttgctcg tgcgcccccc gcgcacggat ggagcaaggc gccccctccg
    19921 tgcggccgtt cgatccggcc gggcgggtca tgtaaggtaa ggcttacctt agttcggatt
    19981 gggaatcggg ggaaccgcaa gtgcagcagt cagaactctc cggccgcatc gcgctggtca
    20041 ccggcgccgg ccagggcata ggcgaggccg tgacccgcgc cctcgtcgcc cggggagcgc
    20101 gcgtcgcggc cctcgactgg actccggacg gcatcaagga cctggaggcc gaattcggcc
    20161 gcgacaaggt caccgcccac actgccgacg tcgccgacag cgccgccgtc gaggccgtcg
    20221 tcgaagaggt cgaggacacc ctcggccccc tcgccatcct cgtcaacgtc gccggggtgc
    20281 tgcgcacctc gcccgtcgtc gacatcaccg acgacacctg gcaccgcacc ttcgccgtga
    20341 actccaccgg cgtcttcaac gcctcgcgcg ccgcggcccg ccgcatgacg gagcgtcgtt
    20401 ccggctgcat cgtcaccgtc ggctccaacg ccgccggcgt gccgcgcacc agcatggccg
    20461 cgtacgccgc ctccaaggcc gccgccacca tgttcaccaa gtgcctcggg ctcgaactcg
    20521 cccgcagcgg catccgctgc aacgtcgttt cgcccggctc caccgacacc gccatgcagc
    20581 gcggtctgtg ggccgacgag gaggcgcccc agcgcgtcat cgacggcgac cccgggtcgt
    20641 accgcgtcgg catccccctc ggccggatcg ccgaacccgc ggacatcgcc gacgccgtcg
    20701 ccttcctcgt ctccgaccgt gcgcggcaca tcacgatgca cgacctgtac gtcgacggcg
    20761 gcgcgacgct gcgcgcctga gcgcaccgtt gtccggggct ccgccccggt ccccggtcct
    20821 cggtatcgcc gggcgggctc aaattttttg agcccgcccg gcgactgagg acaccgcgcg
    20881 cagcgcggtg cggggggttg ggggcgcgcc cccaagaaac ggcgaaaggg cgggtcaggg
    20941 gcaccgatgg cccacaaggc cggctcccac ccggacactt cacgaaacac cacccggtgc
    21001 gacccaccgg aggaacggag cagtaaaggt gaccaccgct caccacgtcg cggatcggcc
    21061 gggcggcagc gagcccggca cccccgtcgg gggtgacacc gtcggcgccg cgacctcgct
    21121 cctcgacgcc tacgaacccg gccgcgcccg gttcttcgcc tcgcccaccc gcaccctcct
    21181 cgcccacggc gtgcgcgccg aggtgccgca cggcgccgcc cccgtggcgc agcgcgtcgc
    21241 cgagacgctc gccgcccggg tgctggccgg tgacgaggcg ccggtcgtcg tcggcgcggt
    21301 ccccttcgac cagggcgcgc ccgccgcgct ggccgtgccc gaggccgtcc gctgggcgcc
    21361 gccgctcgcc gaggacccgc tgatcgccct gcccgcggcc gcgcccggcg ccgcccgctg
    21421 ggacgtgcgg cccgtgcccg agcccgcggg ctacggcgcc gcggtcgccg aggccgtcgg
    21481 ccgcatgcag cgcggcgact tcgccaaggt cgtcctcgcc cgcaccctgg agctctcctc
    21541 cgaccgcgac ctcgacctgc ccgccctgct gcagcgcctg gcccgccgcg acccggccgg
    21601 ctacaccttc gccctgccca ccggccccgg ccgcaccctg ctcggtgcga gccccgagct
    21661 gctggtctcc cggcgcggcg gcaccctcgt cgccaacccg ctggccggct ccacgccgcg
    21721 cagcgccgac ctcgccgagg acgtccgccg cgcggccgcc ctcctgcagt cggagaagga
    21781 cctgcacgag cacgccgtcg tcgtcgacgc cgtccgcgag gccctcgccc cgtactgccg
    21841 caccctgcac gtgcccgagc gccccacgct ggtgcgcacc gccgccatgt ggcacctgtc
    21901 gacgaccgtc accggcgagc cggccgaccc cgcggtgtcc gcgctggagc tggcctccgc
    21961 gctgcacccc acgcccgccg tctgcggcac cccgaccacc accgcgcgcg acgtcatcgg
    22021 cgagctggag cccttcgacc gcggcttctt cacgggcatg gtcggctggg gcgacgcgaa
    22081 cggcgacggc gaatgggtcg tcaccatccg ctgcgccgag gccgaggagc gcaccctgcg
    22141 gctgtacgcg ggcgcgggtg tcgtcgcgca gtcctcgccg gaggccgaga cggccgagac
    22201 cggcgccaag ttccagacgt tcctgcaggc tgtgggggtt gaccagtgac cgagacgacc
    22261 gacgctccgg gctatccggc cgagttcgcc gagcgctacc gcgcggcggg ctactggcgt
    22321 ggagaaacgt tcgggcagat gctgcgcgac cgcgcgcagg cgcacccgga ccggatcgcg
    22381 atcgtggacc ccgccggcga gggccgccgc tggacgtacg gcgacctcga cctgcgcgcc
    22441 gaccggctgg ccgccggctt cctcgcccac ggcatcggca agggcgaccg cgtcgtcgtc
    22501 cagctgccga acgtcgccga gttcttcgag gtcgtcttcg cgctcttccg catcggcgcc
    22561 ctccccgtct tcgcgctgcc cgcccaccgc gagaccgaga tccgccactt ctgcgccttc
    22621 accgaggccg ccgcctacgt catcgccgac gtcagcgagg gctacgacta ccgcgagctg
    22681 gccacgaagg tccgcgccga ggtccccggc ctcaagcacg tcttcgtcgc cggcgagccc
    22741 ggcgagcaca cggcgctggc cggcctcccc accgagccgg tggccgtcga gaacgccccg
    22801 gccccgcacg agctggcctt cctccagctc tccggcggct ccacgggcgt gcccaagctc
    22861 atcccgcgca cgcacgacga ctacatctat tcgctgtggg gctccaacga gatctgcggc
    22921 gtggacgaga acagcgtcta cctgtgcgcg ctgcccgccg cccacaactt ccccctgagc
    22981 tccccgggca ccctcggcgc gctgtacgcc ggcgcccgcg tcgtcctcgc cccccgcccc
    23041 agccccgacg tggccttccc gctgatcgcc gccgagggcg tcacgatcac cggcctggtg
    23101 cccccgctcg ccctcgtgtg gaccgaggcc gcggcggaga ccccgcacga cctgagcagc
    23161 cttcaggtcc tgctggtggg cggcgcgaag ttcagcgagg aggcggcccg ccgggtgcgc
    23221 ccggccctcg gctgcaccct ccagcaggtc ttcggcatgg ccgagggcct ggtgaactac
    23281 acccggctgg acgaccccga ggccacgatc gtcaccaccc agggccgccc catctcgccc
    23341 gacgacgaga tccgcatcgt cgacgacgag gacaacgagc tgcccgcggg cgagaccggc
    23401 cacctgctca cccgcggccc gtacaccatc cgcggctact ggcgggcacc cgagcacaac
    23461 gccacggcct tcaccgccga cggcttctac cgcaccggcg acgtcgtccg gatgacggag
    23521 accggccaca tcgtcgtcga gggacgggcc aaggaccaga tcaaccgcgg cggcgagaag
    23581 gtcgccgccg aggagatcga gaaccacatc ctcgcccacc cggccgtaca cgacgtcgcc
    23641 gtcgtctcca tgcccgacgc ctacctgggc gagcgcacct gcgcctacgt cgtcctgcgc
    23701 gagggggccg agccggtcaa gtcgatcgcc gtcaagaagt tcgtccgcga gcgcggcctc
    23761 gccgccttca aggtccccga ccgggtggag ttcgtgacgg agttcccgca gacgggcatc
    23821 ggcaaggtgt cgaagaagga cctccgcgcg gccatcgccg cacaggtcgc cgccgcagca
    23881 gcacagcact gagaaccgag aaaggctcac cgaccaccat ggcacttcct gccatcgccc
    23941 cgtatcccat gccgcgggag gccgacctcc ccgcgaacaa ggtcggctgg accgtcgacc
    24001 cgagccgcgc ggtgctgctc gtgcacgacc tgcagaacta cttcctcgac gcgttcgagg
    24061 ccggggcgtc gcccgtcacc gagctgctcg ccaacgtcgc cgcggtgaag aaggactgcg
    24121 agcgcctcgg cgtccccgtc gtctactccg cccagcccgg cggccagagc cccgccgagc
    24181 gcggcctgca gcaggacttc tggggcccgg gcctgccgga cgacgagcgc gccaaggcca
    24241 tcgccgacgc cgtcgcgccg acggccgccg acacggtcct gaccaagtgg aagtacagcg
    24301 ccttcgtgcg gaccgacctc gcggagcgga tggccgccca gggccgcgac cagctgatca
    24361 tcgtcggcgt gtacgcgcac atcggcgtca tgatgagcgc ctgcgacgcc tggatgcgcg
    24421 acatccagtc cttcctcgtc gccgacgcgg tcgccgactt ctcggccgag gaccacgcca
    24481 tggcactgcg ctgggctgcc gccaagtgcg ccgtggtgac caccaccgac cggctcttcg
    24541 aaggggcgta acacccatgg cactcaccct cgaacagatc cgggccgacg tcgccgacgt
    24601 gctcggcgag gaccccgccg acatccccga cgacgagaac ctcgtcgact acgggctcga
    24661 ctccgtccgc atcatgaccc tcgtcgagcg ctggcgccgc gaccacggca ccgaggtcac
    24721 cttcgtggcc ctcgccgagc agccggccat agagcagtgg gcaccgctgc tgggggcggg
    24781 gacgtgaacg cccgcaccct cgaccgggcg ggggcacacc ccctgaccgg cacctccggc
    24841 gcgggacggt cccccgcgcc ggaggggctc cccctgaccg ccgcccagtc gggcatgtgg
    24901 ttcgcccagg ccctcgaccc gggcagcccc gccctcggca ccgccgaata cctcgagatc
    24961 cacggcgaca tcgaccccgc gcgcttcgcc gaggccctgc accgcaccgt cggcgaggcc
    25021 gacgccctgc gcgtgcgcat caccgacgcc cccggcggcc cgcgccagct gcccatcgcc
    25081 gtcgaggccc ccggccacgg cttcccgctg cacaccgccg acctgcgcga cgagcgcgac
    25141 ccggacgcga gcgccctcgc ccggatgcgc gccgacctcg ccgagccctt cgacctggcc
    25201 cgcggcccgc tcttctccca cgccctcttc cgcgtcggcg acgagcgctg gctgtggtac
    25261 cagcgcgtcc accacgccgt cctcgacggc tacggctact ccctcgtcgc ccgccgcgtc
    25321 gccgagctct acacggccct ggccaccggc gaggaccccg ccccgagccc cttcggccgg
    25381 ctcgccgacc tcgtcgccga ggacgccgcc taccgcgagt ccgccacgcg cacccgcgac
    25441 cgcgcccact ggctgacggt cttcgccgac cgccccgagg cgccgagcct cgcctccgcg
    25501 ggccccgccg cgcgccccgc cctgccctcc cgcagccacc tgcgcgccac cgcgcacctc
    25561 gcccccgagg cgaccgccag gctgcgccgg ctggccgcat ccgtgcgggc cacctggacc
    25621 gacgtcctct tcgccgccca ggccctctac gtcgcccgcg ccacccgcag cgaggacgtc
    25681 gtcctcggcc tgccgatgat gggccgcatg ggctccgtcg ccctgcgcgt gcccggcatg
    25741 gtcatgaacg tgctgccgct gcgcatgacc gtcacccccg gcacgacgtt tgccgaactc
    25801 gtccaccagg ccgtcctcgg catccgggcc gcccgccgcc accagcgcta ccgctacgag
    25861 gacatccgcc gcgacctcgg cctcctcggc gagggccggc cgctcaccgg cccgctcgtc
    25921 aacgtcatgc cgttcgacta cgggctcacc ttcgccggcg cccgctccga cgcgcacaac
    25981 ctcgcccccg gccccgtcga cgacctcacc gtcggcatct acgaccgcgc cgacggcagc
    26041 ggcctgcgca tcgactacga cgccaacccc gcccgctacg gccaggacga actcgccgcg
    26101 caccaggccc gcttcctgga cctgctgacc cgcctcgccg agcgcgaccc gcacctgccg
    26161 ctcggcggcc tcccgctggc caccgacgcc gagcgcgagc aggtcctcgc ggagttcaac
    26221 gacaccgcga ccgaggtgcc gcccacgacc ctcatcggcc ccgtggaggc ccgcgccgcc
    26281 cgcaccccgc acgccaccgc gctcgtcgac ggcgacctga ccctcaccta cgccgcgctc
    26341 aacgcccgcg ccaaccggct cgcccgccac ctgcgcacgc tgggcgtcgc cccgggcacc
    26401 ctcgccgccg tcgccctgcc gtgctccacc gagctcgtcg tggccctgct cgccgtcctc
    26461 aaggcgggcg gcgcgtacgt gccgctcgac accgcggacc cggccgtgcg cctgcgcggg
    26521 atgctggaca ccgccgcacc ggtgtgcgtc ctgaccgacc gcgccggggc cgccgccctg
    26581 cccgccggcg ccgcgcccgt cgtcgtgctc gacgaccccg cgctcggcga ggcgctggcc
    26641 gcgcacctgc ccaccgaccc cggccgggcc ctgaccccgc agcaccccgc gtacgtcctg
    26701 cacacctccg gcaccaccgg agcccccaag ggcgtcgtcg tgccgcactc ggccatcgac
    26761 aaccggctgc gctggatgca ggcgcagtac ccgctcgccc ccggcgaccg cgtcctgcac
    26821 aagacgcccg tgggcttcga cgtctcggtg tgggagctgt tctggccgct gcgcgagggc
    26881 gccaccctcg tcctggccgg gcccggcgcc caccgcgacc ccgcggaact cgcccgcacc
    26941 gtccgcgaac agggcgtcac cgtcacccac ttcgtgccct cggtgctgca gctcttcctc
    27001 gccgcacccg gcgcggccgc gtgcaccggc ctgcggcacg tcttcagcag cggcgaggtc
    27061 ctgccgcgcg ccacggccga ggagttccac cggctgctcc ccggcacggc cctgcacaac
    27121 ctctacggcc cgaccgaggc ggccgtcgac gtcacccacc acacctgccg gccgggcgcg
    27181 accgggcccg tccccatcgg acggcccgcc tggaacaccc gcctctacat cctcgacgcg
    27241 gccctgcagc cctgcccgcc cggcgtcccc ggcgagctcc acctggcggg cgcccagctc
    27301 gccaccggct acctcggccg gccggacctg acggccgaac ggttcgtgga cgaccccttc
    27361 gcggggcccg gcgcacgcat gtaccgcacg ggcgacctcg cccgctggcg ggaggacggc
    27421 gaggccgagt acctcggccg caccgaccgc caggtcaagc tgcacggacg ccgcatcgaa
    27481 cccgacggcg tcgaggccgt cctgctggcc gacccccgcg tccaggcggc ctgcgccgtc
    27541 gtccgcgagg accggcccgg cgaccgccgc ctggtcgcct acgtgactcc ggtctcggcg
    27601 gatgccgccg ccgagaccgg caccctcttg cggcccgccc cggacgccct gcgcgagtcg
    27661 ctggccgcgc agctgcccga ggccatggtg ccgagcgccg tcgtggtcct ggacgccttc
    27721 cccacgggcc ccaacggcaa gctggaccgt gcggcgctcc ccgcgcccgg cccccaggcg
    27781 gatgccgggg ggcgggcccc cgccgggccc cgcgaggaga ccctgacgcg cctgttcgcg
    27841 gaggtcctcg ggctgcccca cgtcggcgtc gacgacagct tcttcgccct cggcggcacg
    27901 tcgctgctcg cggcccggct cgtcgcccgc gtccgggacg tcttcggcga aggcgtcggc
    27961 gtcatcgccg actccgccgg cggaggggcg gacgacgggg aggacggccc gttcgccatg
    28021 ggcgccctct tccgggcccc gaccccggcc gccctcgccc gcaggctggg cggcggcacg
    28081 gacgtcacgg ccggcttgga cggagcgccg ctggagcccg tactgccgct gcgcgccacc
    28141 ggcagccgca cgccgctgtt cgccctgccc ccggcggcgg gcctcggctg gtgctacgcg
    28201 tcgctgctcg ccggcctcgg ccccgaccag cccctccacg cgctccgggc ccgcgggctg
    28261 acgcccggtg agccgctgcc cgcgacgctg gaggagatgg ccgcggacca cgcggagcgc
    28321 atccgggcag tccagcccca gggcccctac cggctgctgg gctggtcggc cggaggcgtc
    28381 ctcgcgcacg ccgtcgccgt acggctgcag gaggccgggg agaaggtcga gctcctcgcg
    28441 atgctcgacg cctaccccgc ggccgccgcg ttcgaggaac aggccgtcct gggcgccctg
    28501 ctggacatgg caggctgcgc gcaggccgac ggtgccccgc tcacccggga cggcgtcctc
    28561 gccgccctgc gcgccgacgg cggcgccttc gccgcgctga ccccgcgcat gctgcaggcg
    28621 gtggtggacg tcgcgctcgg cacgacggcc ctcgccgggc ggcaccagca ccgcgtcttc
    28681 gacggcgacg tgctgttctt cacggccacg ggcacggcca cggccacggg caccggtacg
    28741 gacggggacg gcccgcgcgc acctggcgcg gggtccgtga cgcgggaggc gtggcgcccc
    28801 tacgtcacgg gtagggtgat caaccgcgat atcgcctgcc cgcacgcgca catgacgcag
    28861 ccggggccgg ccgcggaggt cgccgaggcg gtgacccgcc acctggggga gagctgatgc
    28921 gcgtgagcga cgggccgggc accgcgcccc gggtcctcgg cgaggactcc cttccggggg
    28981 tgtggacgcc cggcccgccg cacgtgtggc tcctgcggac cgaccggccc ctgcccggtc
    29041 ccgtgcagga cccggagcgc atcctcgacg ccggggagcg ggcgcgcgcc gcggcgttcg
    29101 tgcgcgacct gcaccgagag cgctacgtcg cctcgcacac cgggctgagg ctgctcctcg
    29161 gcgcctacct ggccaccgac ccggccgcgg tcgagctcgt gcgcgagccc tgccccggct
    29221 gcggcgggcc gcacggccgc ccggccgccg ccggcgcccc cctgcacttc aacctctcgc
    29281 acgcgggcga cctcgcgctc gtcgccttcg cggacacgcc cgtcggcgcg gacgtggagg
    29341 aggtgcagcc cgccgggacg gcccgggagc tggcgggcgt cctgcacccg gccgagaccg
    29401 cggagctggc cgcgctgccc gcgccgcggc tcccggaggc cttcgcgcgc tgctggacgc
    29461 gcaaggaggc ctacctgaag ggcaccggca cgggcctgtc ggagaacccg tcggtgacgt
    29521 acgtcggcac ggggcccgtc ccggcctcgc ccgccgggtg ggcgctggag gacgtgcccg
    29581 cggcgccggg ttacgcggcg gccatcgcgg tcgcggtcac gggcgcggtc acgggcgcgg
    29641 cggcgaacgc cccgcgctga acggggcgcg gggcgcattc cgggggcgtg cagtggtgaa
    29701 cggctgaata agcggcgtac ggcccgatgg tattcatctg aattacctat agcctgactg
    29761 ttccgcggag ggtcataacg cgcgtcgggg ggaaccatgc cgacctctgc ttcgatcatc
    29821 ttatgcgtct tcgggggcct catggtcctc atctccctgc tcggcagcgg attttccgtc
    29881 agggaaatct cctttccccg gatcagtccc gtgatccggt ccaccgcggc cctcctcggg
    29941 gcgggactcg tggtgacgag cattgtcctg atggcgaacg ggaattcccg cgggagcacg
    30001 cccgggatcg cgggggcgac caccgcgccg ccctccacgc cgccgccctc gccgccgtcg
    30061 gccccgcctt ccgcgccgcc gtccgccggc ccctcgcccg gcaccccggc accgccgccg
    30121 ccggccgtac cgcccacggc cccggccccg ggctccaccc gttccgcgac ggcggccctg
    30181 ctcgagcgcg tgcccgacgc catccgtccc agctgctccg acggcgacgc gtccaagttc
    30241 ccgccgtccg tcgtcgccgt ggtcgcctgt acgccgcccg gcggattccc ggtgatctac
    30301 gcccagttcg tggacggcat cagcacgagc ggcgcctacg accggctgat cggcaacgcc
    30361 acggtcacgc acgacgcgtg cggcccctcg gtcccgctcg acgggcggca gaggtacaaa
    30421 gtcggcggaa agaccgtggg cgacctcacc tgttacggga cttccgacgg cgacgcctat
    30481 ctcacctggt ccagcgagga cctgaacatc atcgcggagg cccacgcccc cctcgcctcc
    30541 tacgggcggc tgtgcgcctg gtggatgacg gcgggaccgc tgcacggcac cggcgcgggc
    30601 gcggccgcct gagaaagcgg gaaacgagaa tggtgaattc ttcccgggaa ttcccggagc
    30661 cgtgatgcac ggagccgccg atttcgtgct ggaagtcagc ggcggtcccg gcgggcggta
    30721 cacggtggcc gtctcctcac cggccggtga ggggagcctc tccgtcgccc tggaccccga
    30781 cgccatcggc gcccgcctcg ccgacctcca gcgggccgtc ctcgcctcct ccgtgacacc
    30841 gcgcgcggcg gcgctcggcc tggagcggcc cgtgcgggag gtcggggagc ggctcttccg
    30901 tgccgtgttc gacggacgcc tgcgcgggct gtacctcgcc agccgccagc acgccggcga
    30961 gcgcgacgag gcactgcgcg tggtcctgcg catccgcgcc cccgaactgg ccgccctgcc
    31021 ctgggagctg ctctacgacg aggagtccgg cgagtacctg tgcctgcgcc ggcccctcgt
    31081 ccgctacgtc gacctgcccg agcccctcgc cccgctgcgc tccgaaccgc ccctgaagat
    31141 cctcggcatg acctcgctgc cccgctcccg cgcgcccctg ggcgcggaga gcgagcgggc
    31201 cgccctgtcc gtcgcgctgg gcccgctgac cgagcgcggc ctggtccacc tcgactgggt
    31261 gcccggccag accgcggagg acctctcccg caggctgctc cggggctgcc atgtcctgca
    31321 cttcatcggg cacggcgcgt acgacccgca gcgccgcgag ggcatggtca ccctggcgga
    31381 cgcggacggg cgtgagcacc acctgcacgc caccgccctc gcctcgctcc tcagtgtggc
    31441 ccggccccgg ccgcagctgg tgatcctcaa cagctgccag agcggcatgg gaaacgccga
    31501 ggacctcttc tccagcacgg ccgccgtgct cgtgcgcacc gtgccggccg tcgtcgccat
    31561 gcagttcgcc gtcaccgaca aggcggccac ccgcttcgcc gcctccttct accaggcgct
    31621 ggcccagggc cgcaccgtcg acgaggccgt acgggtcggc cggatcgccc tggtcgtcga
    31681 caaggacgac agcctggagt gggcgacccc ggtgctctac ctgcgcggcg gggacgcccg
    31741 gctcttcgac atgcccgccg tctgggcgga ggccggaccg gccgtaccgc cggccggcgc
    31801 gggccccgta ccgccgaagc cgcacacgcc cccggaggcg gccgacggcc ggcctgcggc
    31861 tgcggacggc ccgccccagg cacccggcgg cacaccggca ccgcccggcg gcccgcccga
    31921 ggcgcccggc gcggtgatca cctcgcgcgt cctcgacacc cgccagtggg tgcacgccct
    31981 cgccttccac cccgacggca gacggctggc caccgggtcc cgcaaccgcg tcagggtctg
    32041 ggacgccctg accggcaacc ggatatggga gcagccggtg ggcggctggc tctcgtccgt
    32101 cttcgccgcg gcgttcagtc ccggcggccg ccgcctggtc accgggggcg ccgacaacac
    32161 cgtccgcatc tgggcctcct ccaacggcga ggagctgctg cgcctgcgcc acgaccacgt
    32221 cgtcttcggc gtggccttca gccccgacgg cttccgcgtc gcctccgcct ccgccgaccg
    32281 cacggtccgg ctgtgggact ccaccagcgg cgaccccatg ctgcgcatca cccacgacca
    32341 ggtcgtgacg gacgtcgcct tcagcccgga cggcgcgcgc ctcgcctcgg cctcggccga
    32401 ccgctccgta cggctgtggt cgctcggcgg cgacgcgctg ctgcgcctgc gccacgacca
    32461 cgcggtcaag gccgtcgcgt tcagccccga cggcggccgg ctggcgacgg ccggcgacga
    32521 cggctgcgtc cgcgtgtggg acgccggcag cggtcatcag ctcctgctcg tgcggcacgg
    32581 ggacgccgtg aaggacgtgg cgttcagccc cggcggccac tggctcgcca cggcctccgc
    32641 ggaccgcacg gcgggcgtgt gggccgtcgc ggacggtacc cgcatcctgc gcgtgcagca
    32701 ccatcacacc gtcttctgcg tggcgttcgg cccggacggc ggctggctgg ccagcggcag
    32761 cgaggacaag acggtgaagc tgacgccggt gccgggtgaa cgcggatgag cccggcgggg
    32821 aggccgccgg gcccaccaca gggggaccgg tgcaagggga ccggtcccgg ggatcagcgc
    32881 ggggcggtgc agatcgcgac cgctctgatc gtttcggagg cgccgcccgc ggggttggtg
    32941 ttcgtgccgc ggaccaccca ggtgccgccc tcctggaagg agtcggtgaa gaagatgcgg
    33001 aaggcactgg tcttcccgcc gccgccgctg ggcacccggc cggccgggca ggtcgcgacg
    33061 gcgcggccgt tcgcctgcgg cgccacggtc acgggcgggc cctccacctg gtcgaagccg
    33121 ccgatctccg gaccgtcctc ggcgaactcc ttggccttgt ccgcggagac gacgggcttg
    33181 tcgtcggcgg cgttctccgc cgaggcggtg gtgaccaggc cgcccgtgag ggccgcgacc
    33241 gccgccatgg cgaggatgat ggtgcgcttc atgccgacct cctgtgtcgt gaagccgtgg
    33301 gccgcttccc gggggatgcg gaagctccgg atccacaagc tacggaggaa ggcgtgatcg
    33361 agtgcaggga gcgatggtgg gtaccgcggg ggcgtacgga agtgaagccg cttccgtgga
    33421 atgcctgacg cccgggggcg gtggggcgcc cggtgcgcac gggtcaactg ctcgttgccg
    33481 taggcctgtt tcccctgcgc ggctcttgca ccggcgcgcc ccggaagtac cccctgcgcc
    33541 cctcgtgtgg tggatgccct gcttgtccgg ttcacgggca cgctgagtca cgcagcactc
    33601 ggtcgtacag cacgcgctga cagccggtac gcgcaccgga cggcaccagg cagagggggc
    33661 tcccgtgccc gaccccatca cgatcagcat cgaaccgtac caggagggca cggcgacggc
    33721 ctcgtccctc gccggcgacc tcgtcgccct ccccgccgtc cgcgagcgcc tctccggacc
    33781 ccggctgaac gtcgccgact tccggctcct ggagaaggac gccggcaccg acgcgccgtt
    33841 ccgcgccgtc gtccacgacc cggacgccta ccgctcggtc gaggtcaccg gcaggctcgg
    33901 cgacctggca ggggcgaccg cgcgctcggt gcggttccag ccgctgcccg accgggagga
    33961 gttcgaccgg gcggtcgaag cggtgtgcgc gcacgccgag ttcgggcccc agctggcggc
    34021 cgacggcgcc ctcgcgtacc ggcccatgcc gccgctcgcc gacatcaccc acgccgacgg
    34081 caccgtggac cgcgtcgtca ccgtcggcct gcgcaccccc gggagcgagg tcaagcaccg
    34141 catcgtcggc gtccgcacga aggacggcac ggtgatcccg gcccccgagg gagtctccgc
    34201 tccctccgcc ctggactgcg tgaccatccc gcccgccgac aactgccccg acccgtccgg
    34261 cggtccgcgg gccgtccgcg tccgggtgag ccgcgggacc accgaactgt ggaacctggt
    34321 ggtcaaccgg cccaggacct cctccggcgt caacggctcc ggcgcggagc tgcggttcgt
    34381 cgactacaag ggcgaacgcg tcctctacca agcccatgcg ccgatcctca acgtgcgcta
    34441 cacgggcgac cggtgcgggc ccttccgcga ctgggcgaac gaggaggtct gcttcaatgc
    34501 gaccggatcg gacccggtcg gcccgggcta ccgcctgtgc acctcggcgc cgcgcacgat
    34561 cctcgacacc cacagcgacc agggcaactt ccggggcgtc gccttcttcc acgacggctc
    34621 cgcgctccgc atcgtcagcg aactcgccgc gggctggtac cgctacgtca ccgagtggcg
    34681 gctcgccgac gacgggacga tcctgccgcg cttcggcttc tccgccgtca ccaacccgtg
    34741 cacctgcctg gcccacacgc accacgtgta ctggcggctg gacctggacg tcggaggctc
    34801 gaccgccaac cgggtggacg agttcaacga cgccaccggc tggacgcccg tccgcctgga
    34861 gacccagcgc acccgcaacc ccgccggcca ccggcaatgg cgcgtcgtcg ccccggcgac
    34921 cgggcgcggc tacgtcctcg tgccgggcgc gaacgacggc acggcggacg cctacggcgt
    34981 ggccgacctg tgggtcctgc gctaccgcgg cacggagatc gacgacggga ggccctccga
    35041 cacgcgcgcc cacatcggcg acttcgtcaa cggcgaatcc gtggacgggc aggacctcgt
    35101 ggtctggtac ggggcccact tcttccacga cgaggccggt ccgccgcccc cgtcgcacgt
    35161 ggtcggcccg gacctccgcc cggtcgtggt gtgatcgcgg ctcctccccg gggcggcggc
    35221 cggaccgtac gatgaagcgg tgtccgatca ccagaccgcc ggcgcccgcg cccgcgtcct
    35281 cgccgagggg ccgcgggtgg tgatccgggc cgtcacgccg gaggacggcc cggagttcac
    35341 ccggctggtc cgggacagcg cggacctgca ccacccgtgg ctgtccatgc ccaccaccga
    35401 ggagcgcttc gcgcagtacg ccgcccgctt cgacggggag cagcgggcgg gcttcctcgt
    35461 gtgcctgcgc gactccgggc gcccggcagg cttcgtcaac atcaacaaca tcgtgcgcgg
    35521 agccttccag tgcggcgcgc tcggctacgg cgcgttcgtg ccgtccgccg ggcgcggcct
    35581 catgggcgag gggttcgggc tcgtcctgcg ccacgccttc ggcccgctgg gcctgcaccg
    35641 cctggaggcg aacatccagc cgggcaacac ggcgtcactc gcgctggtga agcggcacgg
    35701 cttccggctg gagggcttct ccccggaatt cctcttcatc ggcggggcgt ggcgcgacca
    35761 cgaacggtgg gcgatcaccg cggacatgct ccaggagcac caggattgag accggaccac
    35821 cggagctgac accggaccac cagggttgag agaggttgcc gtgcccacga ccatccgacg
    35881 cgccgtgctg tccctgcccg ccgccccgct cggcgcggag gatccgctgc cgtccctgcg
    35941 cacggccgcc gacgtccacc gcatcgacgc cgagcagcgc agggccctgc cgcccgacat
    36001 ggcccgccag gccggccacg cgcccctgcg gtccctgctg cccgtgcgcc gccgcgacgg
    36061 ctactcccgc aggcgcaccc ccgccgatct agaggcgatc gtcatcgaga acgaccggct
    36121 gcgcgccacc gtcctgcccg gcctcggcgg gcgcgtgcac tccctggagc acaagccgac
    36181 gggccgggag ctgctccacc gcaaccccgt cctgcagccc gcctcgttcg ccctgaacgg
    36241 cgcctggttc tccggcggca tcgaatggaa catcggtgcg accggccaca cgaccctgtc
    36301 cgtggccccg ctgcacgcgg cccgcgtgcc cgcccccgac ggcggggaga tgctgcgcct
    36361 gtgggagtgg gagcggctgc gcgacctgcc gttccaggtc gacctgtggc tgcccgacgg
    36421 ctcggacttc ctctacgtgg gcgtgcgcat ccgcaacccc cacgaccggc ccgcccccgt
    36481 ctactggtgg tccaacatcg ccgtccccga ggaggcgggc acccgcgtgc tcgcgcccgc
    36541 cgaggcggcc tggcggttcg gctacgaacg cagcctgagc cgggtcccgg tgcccgagtg
    36601 ggacggcgcc gaccgcacgt accccctgaa cagcacgcac gcctccgact tcttctacga
    36661 cgtgcccggc ggggagcgcc gctggatcgc ctccctcgac gcggacggcc acggcctcgt
    36721 gcagacctcg accgacctgc tgcgcggccg caagctcttc gtctggggct cgggccgcgg
    36781 tggccggcgc tggcaggagt ggctcacgga gccgggcacc ggcggctacg ccgagatcca
    36841 ggccgggctc gcccgcaccc agctggagca cgtgccgctg gaggcgggcg gcgcgttcgc
    36901 ctggctggag gcctacgggc cgctggccgc ggaccccgcc gccgtgcacg gcggcgactg
    36961 ggcggcggcc cgcggcgagg cggccgcccg gctggaggcg gccctgcccc gcgccgacgt
    37021 ggaagcggcg tacgcggcgt ggcgcccgta cgccgacgcc gagccgaagg agagcctgca
    37081 caccggctcc ggctggggcg ccctggaggc cgagcgcggg cactacgacc tgccgggcac
    37141 gcccttcgcg cccgagacgc tgggggagga gcaggagccc tggctggagt tcctgcaccg
    37201 gggggagttc ccgcggccgg accggagcct gccgcccggt ccctcgctcg tgtcgccccg
    37261 ctggcgcgag ctgctggaga cgatcggcga cggcgacctc tgcggcgcct accacctcgg
    37321 cgtcgcccgc tggcacaccg gcgaccgctc gcaggccgtc cgcgcctggg aggcggcggg
    37381 cggcctgtgg tgggcgaagc gctgcctggc cttcgccgac gccgaggacg gccatcccga
    37441 gcgcgccgcc gaccgctatc tggaggcgtt cggcgaagcc tgcggggagc ggcgcgagag
    37501 cgcctcgtgg gccgccacca tggccgcgct cggccgcgag gcggtggagg cgctgctgga
    37561 cgccggccgg gcggacgacg ccggggccgt gctggacggc ctgcgcccgg gcgtccgcga
    37621 gcgcggccgc ttccggctgc tgcgcgcccg ggtgctgctc gcgcaggggg acgccgcggc
    37681 cgcgcgggag atcttcgacg gcggcttcga ggtggaggac ctgcgagagg gcgacgagtc
    37741 cctcggtgag acctggtacg cgatccaggc gcggctgctg gcgggcgagg ggcccgtcac
    37801 cgaggagatc cgcgtacggg cgcgggcgca ggcgctgccc cggccgtacg acttcaggat
    37861 gcggccggcc ccgtaggcct tccgggccct cgtcgcggcc cttccggccc tctttccggc
    37921 cgtctttccg gtcctcctgc ccggccgtcc cctgcggccg ggctttctgg accgatcatt
    37981 cttgaccgaa cgttctcgaa tcgctacggt cgactcatgg ccaggaccaa ggaattcgat
    38041 ccggatgccg cgctccagtc ggccgtcgag ctgttctggc ggcgcggcta cgaagcgacg
    38101 tcgatggccg acctcgtcgc tcacctgggc atcgcacggg ccagcctgta cgcgacgttc
    38161 ggcagcaagc acgagctcta cctcaaggcg ctgcagcgct acagcgagca gcacagcccg
    38221 cgcatcgccg aggagctctc gcgccccggc ccggccctgc cggccgtgcg ggggctggtg
    38281 acccgcttcg ccggcgaggc ggccgacgac gagctgcggc gcggctgctt cgtcaccaac
    38341 accgccgtcg agctggcgcc gcacgacccc gccgcggccc gcggcgtcga ggagagctgg
    38401 ctcgccctgg aggcggcgct caccgccgca ctgacgcggg cccaggagca gggcgaactg
    38461 cccgccggcc gcgaccccgt ggccctcgcg cggatgctgc tcgtcctgat gcagggcatg
    38521 cgggtggtcg gcaaggcggt acccggccgg gcccggctcc gggacgcggc cgcacaggcc
    38581 ctcgccctgc tggagtgaag gtgacggact cctgctgctt ttccggaccg ctgccgccgt
    38641 cacggcatct catgcaacac acccgccttt atgcgaccca ttgcttagga gtgtcgacat
    38701 gaccgcacgt ttcaccggcc ggaccgtcct cgtcaccggc ggcggtacgg gaatcggcca
    38761 ggccatcgcc ctcgccttcg ccagggaagg cgcgcgggtc gtggtcgcgg gccgccggga
    38821 ggagccgctg aaggagaccg tggccttcgt ggaggcggag ggcggcgagg ccgtcgccgt
    38881 caccgcggac gtgacccggg ccgaggacgt gcgggccctc gtggagcaga ccgtcgcgcg
    38941 cttcggcagc ctcgacgtcg ccgtcaacaa cgtgggtctc gccgtgcccc cggccaaggt
    39001 ggcggacgtg cccgaggagg acttcgaccg gatcgtcggg accaacctca agggcgtctg
    39061 gctgtccatg aagtacgaga tcgggcacat gcgcgccaac ggcggcggcg ccatcgtgaa
    39121 catcgcgtcc aacgtcggcg cccaccgcag gaagcccggc ttcggcgcgt acacggccac
    39181 gaaggcggcc gtctccgccc tgacgcgcaa cgccgcgctg gaccacatcg gcgagggcgt
    39241 gcggatcaac gccgtgagcc ccgggcccgt cgagacgccg atgtcctcgc gccccgggga
    39301 gtcctcgctc gacaaggccg agcgcatgag ccgcgaggtg ccggccggcc gcgcgggcac
    39361 ccccgacgag atcgcgtccg ccgtgctcca cctcgcctcg gacgaggccg gctacaccgt
    39421 gggtgccgac ctcgtcctcg acggcggcgt cacggcctga cggcctccgc ctgctccgcc
    39481 cgctccgccg tcccggcccg ctccggggcg gcggactgcg cggccccgtc ctgcgcaccg
    39541 gcctgcgccg tggtgcggcg ggccgtcagc cacacgtaga cgaggatgcc ggcgaagagg
    39601 aacagcacgc cctggtagac ggccgcgtac ccggcgcccg ccaccagcca gaaggagaag
    39661 gcgaacgcgc ccagcgcgag cgccatgtca cggacgaagc ggccggtgcg gaccttgtcc
    39721 cgctgccccg tgagcaggaa gtacacctgc gcggcggcgg ccagcaggta cgggaccgtc
    39781 gcggagaacg tcgtgatgag gaccaggatc tcgaagaccc cgcccacgcc cgaggtgtag
    39841 ttgacgatgg tcagcagcga ggcgaggacc gcggcggcga gcacgccgaa cgtcggcacg
    39901 ccgcgcttct tcttcccgaa cgcggccggg aacagcccgt ccttcgcggc ggcgtagggg
    39961 gcctgggcgc tcatcagcgt ccagccgttg agggcgccca cgatggagat cacggcgcag
    40021 agggcgatca gcgtgccgcc ccagtggccg ccgaacatca cgtcgacggc gtccgagaag
    40081 ggggccgtgg actccaccag cttgtcgtgc tcgacggtgc cgaagaccga gaccgtgccc
    40141 aggaggtaga ccagcgccgc gcccacggtg cccaggacgc tcgcgcgccc cacgttgcgc
    40201 tccgggtcgc ggacctcgcc cgcgctcatc gcggcggact ccacgcccac gtaggagtag
    40261 agcaggatcg cggccgacgc cgtcagcccg ccggtccagt tgccgtcgga ggtggtgaac
    40321 gagccgagct tgtccgggtc gaagaagaac aggccgacga ccgcgacgaa cagcagcggc
    40381 acgaacttca tcaccgtgga gatcatctgg actgcgccca cccagcgcgt accggccagg
    40441 ttcgcgagcg tgggcagcca cagcatcgcc agcgccatgg cgaggtcccc ggccatggag
    40501 cccttgccgg tcatgacgtg caggtagccg acgccggcca cggcgagggc cgcgttgctg
    40561 acccacgtca tggtccagaa cgaccaggcg gacaggaagc cggcgaagtc gccgaaggcc
    40621 tcgcgcgcgt agacgtaggg gccgccggtg cgcggatggc gctccgcgag gcgcccgaag
    40681 accagggcca gggcgatggc gccgacggtc aggacgccga acgccagcag gctgaccgtg
    40741 ccgaacgggg cgacggacgc gggcagcagg aagatgccgc cgccgatgat gttgcccatg
    40801 accagggcag tggcggtcgg gaggccgaaa cggcgggtgt gcgtgccgtc ggtgtcgtgc
    40861 atgagggggt gtgcctctcg gtccagcggg caggttcgcc aggatgtgcg acacgacatg
    40921 gtgaccggag cggggcggtc cgcaaaatcc tttgtttttg tcccgccacc cccgcccggc
    40981 ggccgcaaat ggtgctgcga gacggccccc gggccgtgat tcgtccagcc gcccccggac
    41041 cggccgccgc ctccgccccg cgcgggcggc acccgcccgg ccacggccga acgacgtcac
    41101 ccgcccgccc gtgtcggccc gctccgcacc ccctgatctg cgaaggtgga cgggggcggc
    41161 agcaggcggc cccggtgccg tacaggcgct gccgctcggt gcggacggcg cggcggtcgg
    41221 aggtacggac ggatgcaggt cagctttccc gcgctcccgg ccggcaccgc gcccgagcgc
    41281 gggctgcccg tgctgccgga gctcgccgcg cgcctcgcgc aggccgcccg ggacagcgca
    41341 cccgaaccgg tcggcggcgg ggacgccctg cgcgccgccg cctgcggcta ctgggcgcgc
    41401 cgcggcctgc cgaccgcgcc cgagcacgtc ctcgccgcac ccggggccca gcccctgctg
    41461 ctcgcggtcc tcgcgggggc cggcggcgac gtcctgctca cgcgcccgtg cgccgcctgg
    41521 taccccccgc tcgcccggct cgccggccgc cccacctacc acgtgccggt gcccgccgag
    41581 tgcggcggcg tgcccgaccc cttcgcgctg ctggagaccg tgcgccggat ccgtgccgag
    41641 ggcggcagac cgcgcgtgct cgtcctgtcg gtcgccgacg accccaccgg ctcggtcacc
    41701 ccgcccgagc tcctgcacga ggtgtgcgag gcggccgtcg gcgaggagct gaccgtcgtc
    41761 agcgacgaga cctggcgcga catgcgccac gaccccggcg gaacggtctt cttcggcccc
    41821 gccgagatgt ggcccgacca cgtcgtcgtc ctcaccgacc tggccggcgg cctcttcccc
    41881 acggcctggc ccgccgccgt cgcccgcttc cccgccgggg ggcgcggccc ggtcctgcgc
    41941 gcccgggtca cctccgcgct cgccgccgta cgggccgagc tggcgccgcc ggtcgccgcg
    42001 gccgccgcct acgccctcga cgagcccggg cccgtccgcg cccgggccgc cgacgcggtc
    42061 cggatctacg gcgccctcgc ccgcgccgcg cgcgagcacc tcaccgcggc cggcgtcctc
    42121 agccgcccct cgcaggccgg gccctacctc tacgccgacc tcggcgagct gcgcgccgcc
    42181 ctcgccgacc gtgccatcac cgactccgtc gagctcgagg cgcacctcag caccgcgctc
    42241 ggccgccccg tgcccggcgg ccaccgcttc ggcgacgacc ccgacgccct gcgggtccgc
    42301 atctccaccc cgcccctcct cggcgcgacc gacgaggagc ggcagcgcgc cctggacgcc
    42361 ccggacccgc tggccgcgcc gggggtcgcc gccgcactga ccagtttcgg atcggccttc
    42421 ggccggctcg ccggcggctg acctaccgtg gccggtcgtg cgagacccgg tgcacgccac
    42481 gccggacacg ccgcaccgct cccggttccc cagcgattgg agccccctcg atgaccgaac
    42541 agaccgagcg ccctctcgcc gagccgcgcc cgctcggcga gatccgcatc tggcccaagt
    42601 cgttcgccga ccgcctcacc gcgcccctgc ccggcgtgcg cgccctcgcc cggctggccc
    42661 gcgaggggcg gctgcgcccc ggcgccgagg ccctgcggga gatcgccgcg ctgccggtcg
    42721 agcccggtcc gctgccggtc accgacgccg ccacggccgc ggtcacctgg gccgggcacg
    42781 ccagctgggt cgtgcgcatc ggcggtctga cggtgctcac cgaccccgtc tggtcgcgca
    42841 ggatcctcgg cacgccgccc cggctcaccc cggtcggggt ccgctgggag gacctgccgc
    42901 cggtcgacgc ggtcgtcatc agccacaacc actacgacca cctcgacgcg cccaccctca
    42961 aacggctgcc ccgtcacacc ccgctgctcc tgcctgccgg gctggcccgc tgggcccggc
    43021 ggcgccgctt cacgcacgtc accgagctcg actggtggga ggccgtcgaa ctgcccggcc
    43081 cggccggccc cgtccgcttc gacttcgtcc cggcccacca ctggagcaag cgcaccctga
    43141 ccgacacctg ccgctcgctg tggggcggct gggtgatgac cgcccccggc gggcagcgcg
    43201 tctacttcgc gggcgacacc ggctacggcc actggttcga gcgcatcggc cgccgctacg
    43261 gcggcatcga cctcgccctg ctgccgatcg gcgcgtacga cccgcgctgg atgctgggca
    43321 cggtccacac cgacccggag gaggccgtcg ccgcctgcca ggacctgggc gcccgggcga
    43381 tggcccccat gcactggtcg acgttcatcc tctcggcaga gccgccgctg gagcccctgc
    43441 gccgcgtccg cgccgcctgg gaggcgacgg gccgcccgcg cgaggacctc tgggacctgc
    43501 ccgtcggcgg gtcccggacc cttcccgggt ggtccggttc ggccccctcc tcgcggactg
    43561 gcccgcttcc cctggccctg cccggcagcg agccggcagg gggcgcgcac ggaggagcgg
    43621 ggacgtagac gcgtgcctac ggccgcgcct cgatgacgtg gacgcagagc ggcacgccgt
    43681 actccgggtg cgtcgtcttc cggtcgtgcc gcatccccag cttgcgcatg accgccgcgg
    43741 gggcttcgtg gccggtgcgg tgcacgccga cgacccgggc gagcccgcgg tcgcggaacg
    43801 cgaagtccag gacggcgcgc gcggcctcgg tggccaggcc gtcgtcccag aaggggcggc
    43861 cgagccgcca gccgacctcc acggccgggc gcagctcggg cagttcggcg ggcacggaca
    43921 ggcccgcgaa gccggccagc cggcgcgacc ggcgcacttc gacggcgaag aggcccacgc
    43981 cgtgctcgtc ccacccctgt tcccaggcgg cgacggcggc cgcggtccgt tcccggtcga
    44041 gcaccgagcc gtcgccggtc cagcgcatca cttcggggtc ggcgttgacg gcggccatcg
    44101 gctcgacgtc gtccgcgcgc cagcggcgca gtgtcaggcg gggcgtgagg agcgtgagtg
    44161 gggaggccat ggcggcatcc tgcccagcgc ggtgccgatt acccggcccc tgccagtcgg
    44221 ctgtccgagt ccggggaggt ggcgggggcc cgggggaaga gcgctcagac ccggcgcccg
    44281 agctgcgcga gcagcacggt ctgcgcgtcg gcgccgggcg gcggctccac cggctcggcg
    44341 aacaggcccg tccccgccag gctgtcgatg tacggctcca cttcacgccg cgtgagctcc
    44401 accagcggtt tgggcagccg ttcgtccgcg ccgatcgcgc gggagaggtc ccacgcgtgc
    44461 acgaccgcgt ccgccgtcat ctgcgagcag tacccgcggg tgtcggaggg cccggaggac
    44521 agctccaccg tccgctccag ggccccgggc gcggcgaacg cctcgcgcgc ggcggcctcg
    44581 gccgcgtccc agacggccac cgggtcgtcc cccagccggt cgccgtccag cgcgtcgccg
    44641 acgtcgtcga tggaccggcc ttccagcagc ggcggaaccc acagctgctc cacggccaga
    44701 tggttgacga ggtcgcgcac ggaccactcg gtgcagggcg tcggttcgtc ccactggccg
    44761 gggcggacgg cgtgcacgcg ctcggtgaac agcgcgagcg cctcccggtg ccggttgagc
    44821 agcgtcgcat cggtcatggg cccattgtcg gggtgcggcg ccccgggcgc ctacccgggg
    44881 gtccgggcgg tgcgtccggg cggtgtggct gtgcggtgcg tcccggcgtt gctgtcggct
    44941 ggggggcttt cgggtggccg gtccggcggc gtcggaaccc gccggcgggg tacacgtggg
    45001 ccatgcggaa gatcgtgagt tcctgggacc gggcggcgtt cctcgcggtg gccgcccggc
    45061 actggcccgg cggcgaccgc gtcctgcccc gcctgtcgcg cagcgccgac cacgggctgc
    45121 tgtggttcgg cgtggcggcg ggcgcggccc tggccggcgg gcggcccgcc cgccgcgccg
    45181 ccctgcgcgg ggtggcgtcg ctggccgtcg cctcggcgac cgtgaacacg gtgggcaagc
    45241 ggtcggtgcg gcggctgcgc ccggtgctgg acgtggtgcc ggtcgtccgg cagctgtccc
    45301 ggcagccctt cacgacgtcg ttcccctcgg ggcactcggc gtcggcggtc gccttcacga
    45361 cgggcatcgc gctggagaac ccggcctggg ggctggccct cgcaccgctg gcggcctcgg
    45421 tgtgcttctc gcgcgtctac accggtgtcc actatccggg tgacgtgctg gcgggggcgg
    45481 cgctgggcgc gggcgccgcg ttcgccgtgc gcggcatcgc gcccacccgc gcccagctcg
    45541 cacccccggc ccggccccgc gcggacgccc cggccctggc gcgcggcgag gggctggtgg
    45601 tggtcgtcaa cgccgggtcc gggcagcggg cggcgggggt gcgcaccgat ccggtgcagg
    45661 aggtgcgctc ggcgctgccg ctcgcggagg tcaccgggta cggccaggac ggcgcgggcg
    45721 agggagggga cctcgggaag gtgctggagt cggcggcgct gcgggcccgg gaactggacg
    45781 gcgccctcgg cgtgttcggc ggcgacggca ccgtcaacgc ggccgccgtc gtggcccggc
    45841 gccaccggct gccgctcgcg gtcctgccgg gcggaacgta caaccacttc gcctacgacc
    45901 tgggcatcga gtccctcggc gacgcctgcc gggccgtgga ggccggagag gccgtggccg
    45961 tcgacatggt gcggatgtgc gcgggcggcg gcgaggaggc gggctggttc ctcaacacct
    46021 tcagcatcgg cgcgtacccg gaactggtgc gcgtgcgcga gcgctgggcg ccgcgcgtcg
    46081 gggcctggcc cgcgggcgtg ctggcggcgg tgcacgtgct gcgcacggcg cggccgctcc
    46141 ggctggaggt ggacggcagg cggcgccggc tgtggatgct gttcgcgggc aactgcacgt
    46201 accgcgggct gggtctcgcg ccggtgcggc ggcacgacct ggcggacggc gtgctggacg
    46261 tccgcacggt ctcgggcggc ccgctggccc gcacgcggct gctcgccgcg gcgctgggcg
    46321 gcggcctgaa gcactcgccg gtgctcagga cggcccgggt gcgcagcctg cggatcagcg
    46381 gcatccggcg ggggacgcac ctggcgtacg acggtgaaat cgccgccgcc cccggcgaat
    46441 tgacgctgcg gaaggagaac gaggcgctgg tggtgtaccg cctgcccgcg gagtgggacc
    46501 tgaggggacg cggcgtctga caggtgaggt ctgaaatgtg agacggcact ctcgaaatcc
    46561 gagacaaggt tctacggtgc tgtcatggct gacgacgaaa ccaccgtgta cacccatggc
    46621 catcacgagt cggtcctgcg ctcgcacgcc tggcgcacgg ccgccaactc cgccgcgtac
    46681 ctgctgccgg agctggagcc gcacctggag atcctcgacg tcggctgcgg gccgggcacc
    46741 atcaccgccg acctggccgc cctggtcccg cagggccggg tcgccggcct ggacgccgcc
    46801 gaggaggtcc tcggcgcggc ccgtgcgacc gccgccgccc gagggctgac caacaccgac
    46861 ttcaccgtcg gtgacgtccg ggccctggac ttccccgacg ggtccttcga cgtcgtccac
    46921 gcccaccagg tgctccagca cgtcggcgac cccgtgggcg cgatgggcga gatgcgccgc
    46981 gtctgccgcc ccggcgggct cgtcgccgtc cgcgacgcgg actactccgc catgacctgg
    47041 tacccggccg tccccggcct ggacgactgg caggacctct accggcgtgt cgcccgcacc
    47101 gccggcggcg agcccgacgc gggacgccgc ctgctgtcct gggcccggcg ggcgggcttc
    47161 acccgcgtgt cggccacggc gagcgcgtgg tgctacgcca ccgaagagga acgctcctgg
    47221 tggagcggtc tgtgggcggc ccgcacgacc gcctccgcgt acgcccggct cgccgtggac
    47281 ggcggacacg cggaccgggc cggcctcgac cggatcgccg ccgcctggcg ggagtggggc
    47341 cgccacgagg acgcctggtt cgccgtgctg aacggcgaac tcctgtgccg cgcctgaacc
    47401 gtcccgcacc gtgccgcgcg gccaactagc cttgctccca tgaacattct ggggacctcg
    47461 ctacgggtgt gcgtcgatga tctggaccac gcgatcggtg tctacgaacg cctgaccggt
    47521 gccgaggcgc tgcgcttcca ccgcggcggc gtcgcggtgg ccgcggtcgg ctgcttcttc
    47581 ctcatgagcg gaccggagaa ggagctgtcc atcctgcgca agatcaccgc cacgatcgcg
    47641 gtgacggacg tggaggaggc actcggcgac ctggaggcgg taggcgccca gatcatcgcc
    47701 ggcccggtac cgaccccgat cggccgcaac ctggtggccc gccacccgga cggctcggtc
    47761 ttcgaatacg tcgaccgcaa acagggttga acgggcctcc gtttgccccg ggggcgtcca
    47821 cgacagtcgt catgatccga ccgtgccgcc ccgcccccgg ggcgccccgc cccaggccgg
    47881 gtcagcccag gtcgagggcg ttgcgcagtc ccatccggta gcggatcgcg tcctcggccc
    47941 tgaacagttc gagctcgggg gcccggtaca gcggggtgat cgtgcaccgc tccgcccgcg
    48001 aacccgtctc gtccagcagg gcgttgaccg cggcccgtgc cgcggcgttc gcgccctcca
    48061 tggtcgcgag gtcgatgtcg gtggccacgt agtccccgca caggaagagg ttggggatcg
    48121 ccgtgcgcgc cgcggggcgg ttgtaccagg tgccggcggg gtggacgagg agctgttcgt
    48181 cgttgaccgg gcgggggccg ccgatctcca cggccgggtc caggaaccag gagtggatct
    48241 tcgcgtcgct caggacggtg cgcccggtgt cgttgagccc ggccttcatc tgcgcccaca
    48301 cctcgcgcgc gacctcctcg cgcgtgcact gcttggcggt cttgccgtag aggatgccgg
    48361 gcttgtccca ctcggagacg tccaccgaca ggcagtccgc ggccgcgccg tccccgtagt
    48421 cgcggcggaa gtcgcgcccc gaccagtact gcgcctgccc cacggaggtg atcgaccagg
    48481 gggagtcgat gtggttgacg tgcccgtgca ggacgggtgt gggctccgtc agatagaact
    48541 ggatgcccgt catccagtcc gtctgcagct tgtcgcagcg cgccagctgc gggtcggccg
    48601 cccgcacctg ggcgttccag gtggtacggg cgtgctcgac gggcatcgcg gagacgaagt
    48661 ggtcggcggt caccgactgt ccggcgccgg aggcgtcctg cacgaccgcc tcggtgatcc
    48721 ggccgcgcgc gatccgcagg tcccgtacgg cccagccgat ccggaacgtg acgcccaggg
    48781 agcggaggtg agcgacccac gggtcgatcc acgcctcgtt ggtgggggcg ttgagcaccc
    48841 ggtccggctc gccgtccgcg ccccgcccca gggcgttgaa aaggaacgcc tcgatgcacg
    48901 tcgacaccgt cttggtg
//
