LOCUS       NZ_LNBE01000003        42916 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces roseifaciens strain MBT76 scaffold_3, whole genome
            shotgun sequence.
ACCESSION   NZ_LNBE01000003
VERSION     NZ_LNBE01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseifaciens
  ORGANISM  Streptomyces roseifaciens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 2630732)
  AUTHORS   Wu,C., Zhu,H., van Wezel,G.P. and Choi,Y.H.
  TITLE     Metabolomics-guided analysis of isocoumarin production by
            Streptomyces species MBT76 and biotransformation of flavonoids and
            phenylpropanoids
  JOURNAL   Metabolomics 12, 90 (2016)
   PUBMED   27073352
REFERENCE   2  (bases 1 to 2630732)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     The complementarity of genome-mining and NMR metabolic-profiling
            facilitates lead-finding
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 2630732)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2015) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.06
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001445655.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 03:28:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,528
            CDSs (total)                      :: 7,450
            Genes (coding)                    :: 7,245
            CDSs (with protein)               :: 7,245
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 205
            CDSs (without protein)            :: 205
            Pseudo Genes (ambiguous residues) :: 0 of 205
            Pseudo Genes (frameshifted)       :: 77 of 205
            Pseudo Genes (incomplete)         :: 168 of 205
            Pseudo Genes (internal stop)      :: 20 of 205
            Pseudo Genes (multiple problems)  :: 56 of 205
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:37:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 458747
            Orig. end                         :: 501663
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LNBE01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..42916
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T1PKS"
                     /region_number="2"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..42916
                     /SMILES="CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..42916
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:22916](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..22916
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     misc_feature    complement(886..899)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    complement(1307..1320)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.03"
                     /tool="antismash"
     misc_feature    complement(1338..1352)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 23.72"
                     /tool="antismash"
     misc_feature    1391..1406
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.77"
                     /tool="antismash"
     gene            1472..2677
                     /locus_tag="AS857_RS07990"
     CDS             1472..2677
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766689.1"
                     /locus_tag="AS857_RS07990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_058042433.1"
                     /sec_met_domain="p450 (E-value: 1.8e-22, bitscore: 76.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAAEAKAIVDLEAMGEEFARHPHRVYAGLREQGPVHRVRMPEGA
                     EAWLVVGYDEVRATLNDPRLTKDWAKSSSDISLIRASVGPNMLVLDAPDHTRLRKLVAR
                     EFTPRRVEGMAPRVQQMTDELLDAMLAAPGRRADLVEALSFPLPMGVICDLLGVPDLDR
                     EAFRHWSNIGVGAGPAEEKATAAREVTAYLNALIAAKRREPGDDLMSALISAADEGGDR
                     LSPEELLGTAWLLLVAGHETTVNLISNGVLALLQHPDQLAALRADPGLLDNAVEEMLRY
                     DGPLETPTYRFTTEPLEIGGTLIPGGGELVLPVLADADRDPARFPDAGRFDIRRDARGH
                     VAFGHGIHYCLGAPLARLEARAAIGSLLERCPDLALDAHPDSLTWREGLLIRGPHRLPV
                     RF"
     gene            complement(2701..3408)
                     /locus_tag="AS857_RS07995"
     CDS             complement(2701..3408)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044569.1"
                     /locus_tag="AS857_RS07995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6875 domain-containing protein"
                     /protein_id="WP_058042434.1"
                     /transl_table=11
                     /translation="MNHGNDHCTLPDGGGADSGLARIRLYDQREAAAEELLRPVHEWIS
                     GHVARPHPDLGRRGAVCPFVPLSQRLGLIRYALAEPPVRDEAGLVAAVAALKAHWLAME
                     PHSGQHTIDKTIVLVLPGVAAATVVRVHDRLKPEFVAEGMMLGEFFPGHPGPGLHNPGF
                     RPLHSDTPLLVARSMVGNDLPFLAEQRYPPARRAGFVESFLRHQPGASPVARQRARAEL
                     ERARDELGHPPPA"
     misc_feature    3433..3447
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.41"
                     /tool="antismash"
     gene            complement(3534..4163)
                     /locus_tag="AS857_RS08000"
     CDS             complement(3534..4163)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013933.4"
                     /locus_tag="AS857_RS08000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LysE family transporter"
                     /protein_id="WP_160330200.1"
                     /transl_table=11
                     /translation="MEELALGVALGFSAGISPGPLLALVLSGTLRGGLGVGLRVAAVPL
                     LTDLPVIVLAVTVLAVLPERAIAGGGVLGGLFLAWLAVSTLREARTAEVPEACDTAEAR
                     VRGRRTLWQGALVNLLSPHPWMFWLTTGAPLLVAAWRNGPPGAGGFLFGFYGLLVGSKA
                     ALAVVVARARHRIGTRGYRLLLGGSGVLLLAASALLLVEFGSALTA"
     misc_feature    complement(3570..3572)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    4216..4232
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.67"
                     /tool="antismash"
     gene            4389..5138
                     /locus_tag="AS857_RS08005"
     CDS             4389..5138
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018537574.1"
                     /locus_tag="AS857_RS08005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_058042436.1"
                     /transl_table=11
                     /translation="MANQPPLQFSLDRSSPVPLYYQLSQQLEAAIEQGGLAPGSLLGNE
                     IDLAARLGLSRPTVRQAIQSLVDKGLLIRRRGVGTQVLHSQVKRPLELSSLYDDLEAAG
                     QHPATRVLHHGTEAAAAGVAAALGVPEGTEVLRIERLRLAHGEPMAHLCNHLPVGLLDA
                     GPARLEETGLYRLIRAAGITLHSARQTIGARAATAEEGERLAEPEGASLLTMERTTYDD
                     TGRAVEYGSHVYRASRYSFEFQLLVRP"
     misc_feature    complement(5204..5218)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.84"
                     /tool="antismash"
     gene            5426..6406
                     /locus_tag="AS857_RS08010"
     CDS             5426..6406
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1205: ABC
                     transporter, carbohydrate uptake"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007454899.1"
                     /locus_tag="AS857_RS08010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="WP_173864733.1"
                     /transl_table=11
                     /translation="MSAVLAAVLGATLAGCSATGGKRAEERAAKAAQGRAAVDTPRWTF
                     AMVTHSGDGDTFWDIVQSGAKQAAAKDNIKFLYAHDVEGNKQAQSVQAMIDQKVDGLIV
                     TLAKPDAMKDVVAKAKKAGIPVITVNSGSDKSKEFGALTHIGQDEVIAGEAVGEQLNER
                     GKKKAVCVLHEQGNVGHEQRCDGVKKSFKGEVQNLYVEGTNMPSVQSSIEAKLQSDKDI
                     DAVVTLGAPFAPTAVKAAEQAGSKAEVDTFDLNAKVAEALQSGKLGFAVDQDPYLQGYE
                     AVDLLWLYRYNRDMLGGGRPVLTGPQIVTKDDAKTLAEYAKRGTR"
     gene            6403..7455
                     /locus_tag="AS857_RS08015"
     CDS             6403..7455
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1113:
                     inner-membrane translocator"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037304.1"
                     /locus_tag="AS857_RS08015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter permease"
                     /protein_id="WP_058042437.1"
                     /transl_table=11
                     /translation="MSAPATAPVQDAPDERLMHRSHLRRLLGRPELGAVVGAVAVFVFF
                     SVVADSFLQTSSLSTVLYASSTIGIMAVPVALLMIGGEFDLSAGVMVTSAALVSSMFSY
                     QMTANVWAGAGVSLLAMLAVGFFNGFVLTRTKLPSFIITLATFLMLTGLNLGFTKLIGG
                     TVSTKTIGDMEGFESARAVFASHLTIGGVDLQVTILWWLGLVALATWVLLRTRAGNWIF
                     AVGGNSDAARAVGVPVKGTKIALYMAVAFCAWISGQHLLMSYDVVQSGEGVGNELLYII
                     AAVIGGCLMTGGYGSAIGSAVGAFIFGMASKGIVYAQWNPDWFKFFLGAMLLLATLLNA
                     WVRKRAEARK"
     gene            7452..8279
                     /locus_tag="AS857_RS08020"
     CDS             7452..8279
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153144.1"
                     /locus_tag="AS857_RS08020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_058042438.1"
                     /transl_table=11
                     /translation="MSAAALVKLTDVSKFYGNIRALEGVSLEVHAGEITCVLGDNGAGK
                     STLIKIVAGLHQHDAGSFEIEGEETKLASPREALDRGIATVYQDLAVVPLMPVWRNFFL
                     GSEPTKGAGPFKRLDVQHMRETTRSELLRMGIDLRDVDQPIGTLSGGERQCVAIARAVY
                     FGAKVLVLDEPTAALGVKQSGVVLKYVAAARDAGLGVVLITHNPHHAYLVGDRFVLLKR
                     GSMAGSHAKSEIGLDELTRQMAGGSELEQLSHELQRAPGPDVIGGKPVASGEG"
     gene            8482..9600
                     /locus_tag="AS857_RS08025"
     CDS             8482..9600
                     /EC_number="2.7.1.2"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006096 - glycolytic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942501.1"
                     /locus_tag="AS857_RS08025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ROK family glucokinase"
                     /protein_id="WP_058042439.1"
                     /transl_table=11
                     /translation="MSMYRDLHRGAAKATVLRTVGTRERRSHLTAPRVPTVGIDIGGTK
                     VMAGVVDADGTILEKVRTETPDKSKSPKVVEDTIVELVLDLSDRHDVHAVGIGAAGWVD
                     ADRNRVLFAPHLSWRNEPLRDRLAGRLAVPVMVDNDANTAAWAEWRFGAGRGEDHLVMI
                     TLGTGIGGAILEDGQVKRGKFGVAGEFGHMQVVPGGHRCPCGNRGCWEQYSSGNALVRE
                     ARELAAAESPVAYGIIDRVGGNISEITGPLITELARSGDAMCVELLQDIGQWLGVGIAN
                     LAAALDPSCFVIGGGVSAADDLLIGPARDAFRRHLTGRGYRPEARIVKAQLGPEAGMVG
                     AADLARLVARRFRRANRRRVERYERYARAGRA"
     gene            9600..10172
                     /locus_tag="AS857_RS08030"
     CDS             9600..10172
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017944437.1"
                     /locus_tag="AS857_RS08030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_063804202.1"
                     /transl_table=11
                     /translation="MSTTEHPERTAPPHGPGQPDDGFRRRCLKAVVVFLLIAIPAGYLY
                     ISAMQSRGGSESKKEQAAASGLEEGWPTRLQRRLYEVTVPPYAEDVASYETNAWKASSL
                     FLQFTTTREKFDKWLSDVGTSASELEDGEVTIDEDEAAEVGWDLGGEHRWAGTTVDQDK
                     PKPSLEITANLDDPKYPRVFVVSTTTP"
     misc_feature    10382..10396
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    complement(10404..10419)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            11677..11934
                     /locus_tag="AS857_RS37365"
     CDS             11677..11934
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013088.4"
                     /locus_tag="AS857_RS37365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="EamA family transporter"
                     /protein_id="WP_079110172.1"
                     /transl_table=11
                     /translation="MRLRHLPAGTVGLIGLLNPVTGVQLGTSVAGETLTVQQLCGLVLL
                     LAGVVLGQPKPAGRRDRSQVPPHAVADERSAQASSKRDAL"
     gene            complement(12037..13242)
                     /locus_tag="AS857_RS08045"
     CDS             complement(12037..13242)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042915.1"
                     /locus_tag="AS857_RS08045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MAB_1171c family putative transporter"
                     /protein_id="WP_144440756.1"
                     /transl_table=11
                     /translation="MEIAVQVTLWLVAIWRIPSAFRSPQQRMLWATFMLWAIARSLSNG
                     SLADYIDWTTGTEDLATLLKHLLGVLSSITALRFVGIITGADVRNPRNPRTRLIAACAT
                     LLTMCALFVMSETIIHDSPEQLLSGSPPSWGTIAYWVALELYIGIGLASVAALLWRAGR
                     LAAQPFLRWGLLCISVGAALDLVYAVYKITLLSILASGAAVPVELAAKAANSLQAIAIL
                     LMAIGSIIPATNVSWRMWQRCLTLRRLAPLWRTFQREYPQVVLDSSESGALADLVGLRQ
                     SHLRLYRRVIEIRDGMLFLQPRISQRLYDTAHRHVVSSGVTGKDLVEATAIACCLRKVL
                     APGNRDSSPDESMRLNMPGRDDLNQEARFLAQISRAFHRSTVVNNFLSIQPEPGSQPTS
                     TR"
     misc_feature    complement(12661..12663)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13249..13824)
                     /locus_tag="AS857_RS08050"
     CDS             complement(13249..13824)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AS857_RS08050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216823957.1"
                     /transl_table=11
                     /translation="MKLSKFRSSNLSRFRKPGMGEVRKRCEALLADIWVPSPFDIAEFC
                     AYVGGQRSRRISLRPTRGLSETTPCGMWLSIGETDYIFYEDNTSRLHSEHIILHELSHM
                     LSGHSFTDPNVSDVLSRLMPNLNPAVVRQALGRVSYSTEQEQEAELLASLIRQQAGRVQ
                     LLNEDARKDLLLRDLSQAFSNQSPASRG"
     misc_feature    complement(13633..13635)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    13934..13950
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.55"
                     /tool="antismash"
     gene            complement(13963..14385)
                     /locus_tag="AS857_RS08055"
     CDS             complement(13963..14385)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AS857_RS08055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_058042443.1"
                     /transl_table=11
                     /translation="MDNRPAQAFSIAEKLDRLFTTTGKRKHGECSYTAVAESIREEQGI
                     SISHTYIWQLRTGRRDNPTLQHLTGLANFFGVPVAYFLDDKITEEIDSELQLLAALRNA
                     GVTEIAMRAADLSSGSREAVSSMINKFWELEGGENR"
     gene            14562..16340
                     /locus_tag="AS857_RS08060"
     CDS             14562..16340
                     /NRPS_PKS="Domain: CAL_domain (45-483). E-value: 6.3e-116.
                     Score: 379.6. Matches aSDomain:
                     nrpspksdomains_AS857_RS08060_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="AS857_RS08060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_216823958.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 8.4e-224, bitscore:
                     742.9, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-85, bitscore:
                     284.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVEVNELANSSFTHHVRDRLLAYGDDRFYTFVKDGVDGLVEDRV
                     SYRGLDSAARSLAAWFTSSVHAGKPALLLFPAGLDFLQTFLGCLYAGVIAVPAPVPTDP
                     RSYRRVANIVADTGLELVLTTSSLLDELREKLPELSETRLDVRAVDQDCAGTADDWRMP
                     SLGLESVAFLQYTSGSTSEPKGVMVTQGNLLHNEGEIASRMSLGDELVMTGWLPHFHDM
                     GLIGMLLYPLYAGGDCTFMAPGTFLKRPVRWLQVVSQTRANLTVAPNFAYDMCVRTITD
                     EQLSALDLSSLKAVLNGAEPVRAKTLADFSARFAPAGFRPEMFVPCYGMAEVTLLATSV
                     DVGARPQVTKVDRMALERDEIRLDDGEQSTSLVSCGVPSTLDIRIVEPATRVERAVGQV
                     GEIWLRGGSVAAGYWNRPDTNREIFQAHTADGDGPFLRTGDLGVLLDGQLYVTGRLKDV
                     LILRGRNLYPQDIEYVVSELHPALAAGTGAVFSVQADGEHVVVLHEIKRGLLGELSMDE
                     LSGRISVHVARTFDIPAPSVVLTNRGVVQKTTSGKVQRRLMRDLFLSNGVKALHESLRP
                     AVHGLKAIPATAEGQR"
     aSDomain        14697..16010
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08060_CAL_domain.1"
                     /evalue="6.30E-116"
                     /label="AS857_RS08060_CAL_domain.1"
                     /locus_tag="AS857_RS08060"
                     /protein_end="483"
                     /protein_start="45"
                     /score="379.6"
                     /specificity="Minowa: NH2"
                     /tool="antismash"
                     /translation="SYRGLDSAARSLAAWFTSSVHAGKPALLLFPAGLDFLQTFLGCLY
                     AGVIAVPAPVPTDPRSYRRVANIVADTGLELVLTTSSLLDELREKLPELSETRLDVRAV
                     DQDCAGTADDWRMPSLGLESVAFLQYTSGSTSEPKGVMVTQGNLLHNEGEIASRMSLGD
                     ELVMTGWLPHFHDMGLIGMLLYPLYAGGDCTFMAPGTFLKRPVRWLQVVSQTRANLTVA
                     PNFAYDMCVRTITDEQLSALDLSSLKAVLNGAEPVRAKTLADFSARFAPAGFRPEMFVP
                     CYGMAEVTLLATSVDVGARPQVTKVDRMALERDEIRLDDGEQSTSLVSCGVPSTLDIRI
                     VEPATRVERAVGQVGEIWLRGGSVAAGYWNRPDTNREIFQAHTADGDGPFLRTGDLGVL
                     LDGQLYVTGRLKDVLILRGRNLYPQDIEYVVSELHPALA"
     CDS_motif       15072..15128
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08060_0001"
                     /evalue="6.90E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="AS857_RS08060"
                     /protein_end="189"
                     /protein_start="170"
                     /score="24.8"
                     /tool="antismash"
                     /translation="AFLQYTSGSTSEPKGVMVT"
     CDS_motif       15747..15833
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08060_0002"
                     /evalue="5.60E-10"
                     /label="NRPS-A_a6"
                     /locus_tag="AS857_RS08060"
                     /protein_end="424"
                     /protein_start="395"
                     /score="31.5"
                     /tool="antismash"
                     /translation="VGQVGEIWLRGGSVAAGYWNRPDTNREIF"
     CDS_motif       15915..15977
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08060_0003"
                     /evalue="2.80E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="AS857_RS08060"
                     /protein_end="472"
                     /protein_start="451"
                     /score="13.7"
                     /tool="antismash"
                     /translation="TGRLKDVLILRGRNLYPQDIE"
     misc_feature    16281..16283
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16349..18031
                     /locus_tag="AS857_RS08065"
     CDS             16349..18031
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012656.4"
                     /locus_tag="AS857_RS08065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_216823959.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.2e-12, bitscore:
                     44.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.3e-10, bitscore:
                     38.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSLAEEFDHRLGDPRAPAAIFSYARCTELDRAEEFPGEICDLLN
                     ALGLQQYYVPEPIGGKLRDFPVPLQLIRAVARRDLTVAIAHGKTFLGGVSAWISPASAV
                     TRAVADQVISGAPVSWGLTERAHGSDLMAGEVRAQEVPGGYRLTGEKWLINNATRGRTI
                     TVLANTGGGPRGFDVFVVDKMALAPTEFTCLPGVRTHGIRGADISGIAFMGAFVPASAR
                     LGAPGTGLETVLKGLQLTRTLCAALSLGAGEHSLRLALEFAEGRQLYGRGLLELPYAVR
                     TLADAGADHLLNEAVALVGSRCIHGQTGEMSLVSAIAKYLLPTRTDRMISTLGRFLGAR
                     SQLTNVDIDGRFQKLARDHRIVGIFDGNTLVNLNSIINELPVVARHAATPYDTAALRTT
                     LDPDEPLPEFDANHLRLVSRAGSSLLRAFPDLVRQMEHTPTGEHAARILEHYQDLLSEL
                     ADHRPVRITVPRRSFVLAERLSLCWAAAAVLGISAHTSQSDPLWANGLWQRAVLGRILE
                     ALGDAVARQAGQDEALVDALQARLQQGLSLSLLPHRVAEGTSR"
     misc_feature    17486..17488
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            18028..19686
                     /locus_tag="AS857_RS08070"
     CDS             18028..19686
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012656.4"
                     /locus_tag="AS857_RS08070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_058042446.1"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4e-11, bitscore:
                     40.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.3e-15, bitscore:
                     53.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVGLDSLENLFGDPFDDENPVGFAGVLAADEQAVPLADGELLL
                     DKWNFNHEFVPRSLGGRLTGVDELARRLRPVFRRDPALGLGYGVTSLMAAVNVWAAGST
                     NQRRRVADDLLAGKRIAVAFHELAHGNDFLRNEFAARLTADQIVLSGTKQVINNIERAE
                     SLVLLARSADAPGPRAHSTLLIDKRDLPEDSVRYMPRFTTSGMRGCHLGGVVFDNVPVG
                     LDALVGTPGQGVETALRAFQVTRATLPGMAIGTLDSALHLAHDFAASRRLYGHTVADLP
                     HARGTLAAAFTDLLIADCLATAVSRGLHLAPRASSAPAAAVKYLVPLLLEEAHHELSVI
                     LGARSYLREGRHAAFGKFSRDLPLVSIGHAGATSCLLTVLAQLPTLAKRSWSPAAPPAK
                     LFDTAIALPELDISGLSVSDKAPDPLMSTLAQVRPDDGLPGLFATALAELHADSLRLPA
                     GELGPAASAEAFELAKRYTLLLAAAACLGTKQFATSEFLSSPQWLTAALTRLAARLGHG
                     DGVLDDELAEPLFGELTTRVDQRLSCGTDRSSIFG"
     misc_feature    18529..18531
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            19729..20004
                     /locus_tag="AS857_RS08075"
     CDS             19729..20004
                     /NRPS_PKS="Domain: ACP (14-82). E-value: 1.2e-20. Score:
                     65.6. Matches aSDomain: nrpspksdomains_AS857_RS08075_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010985080.1"
                     /locus_tag="AS857_RS08075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyl carrier protein"
                     /protein_id="WP_058042447.1"
                     /sec_met_domain="PP-binding (E-value: 2.6e-15, bitscore:
                     53.8, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLNTEISPVELEFWLIERVASYLRLDTREVDPQESFANLGLDSV
                     YALTLTADIEDTLGIEVEPTLAWDYPTISALAKGLTASMRAAKETV"
     aSDomain        19771..19974
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08075_ACP.1"
                     /evalue="1.20E-20"
                     /label="AS857_RS08075_ACP.1"
                     /locus_tag="AS857_RS08075"
                     /protein_end="82"
                     /protein_start="14"
                     /score="65.6"
                     /tool="antismash"
                     /translation="WLIERVASYLRLDTREVDPQESFANLGLDSVYALTLTADIEDTLG
                     IEVEPTLAWDYPTISALAKGLTA"
     gene            20001..22916
                     /locus_tag="AS857_RS08080"
     CDS             20001..22916
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (3-415). E-value:
                     2.1e-159. Score: 522.9. Matches aSDomain:
                     nrpspksdomains_AS857_RS08080_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (517-798). E-value: 3.2e-92.
                     Score: 301.0. Matches aSDomain:
                     nrpspksdomains_AS857_RS08080_PKS_AT.1"
                     /NRPS_PKS="Domain: PP-binding (891-959). E-value: 7.5e-14.
                     Score: 43.8. Matches aSDomain:
                     nrpspksdomains_AS857_RS08080_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003959528.1"
                     /locus_tag="AS857_RS08080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_058042448.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 3.9e-83, bitscore:
                     276.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_KS (E-value: 8.2e-158, bitscore:
                     522.9, seeds: 2284, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.2e-90, bitscore: 301.0,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 3.5e-13, bitscore:
                     46.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEIAIVGIDGRFPGAANPAEFWDLLMRGADAISTVPDDRWDPDA
                     LLGSGRLNTTTGGFLTDPDVFDHEFFGISPKEAEAMDPQQRLMVQVAWRALEDACLDPR
                     AQAGTATAVFIGVMGNEWAHLHMTDYDRITPHLGSGNGYCMIANRLSYLLDLKGPSWAV
                     DSACSSSLVAVHQACSALRLGECDQAIVGGVNIMMTPALNIFYTQAGLSAPDSACKPFS
                     AEANGIVRGEAVAAVVLRRLADAEAAGLPIYGVITGSAVNQDGRSNGLTAPNRWSQEQV
                     IRDAYRKAGVGPEQIAAVEAHGTGTVLGDMIEANALGAVHGVDRPTPCGLGSLKGNIGH
                     TEGAAGISALIKMALAAHHGVVPSSRHADTENPQLALRAKGLRLLKAPQRLKGTAPLLA
                     VSSFGLGGTNAHLVLRGHRTTPLPERPAPGIVTLSANSSAGLQRNATQLATDLAKLPER
                     SFARLCWTSNQVKSTGKHRLAFAASGSQDAAAALRRFTEDPAFADGISDVAQRDVRVGW
                     LFTGQGSPYPGMTRALHDRFAGYRQALADVDQAMAEHLGRSVSSVILGEEPLIQQTGLA
                     QPAIFAVGYAMSVMLSELGVQPDWLIGHSVGEFAAAVHAGVLALPDACELVTARARLMQ
                     ELPSGGGMLAVRGEPAEVLDLLDGTVGIAALNGPEDTVCSGPVDELERIAKTLQERGIT
                     TRTLDVSHAFHSPLMEPMLAEFAAVAVKFTYRPATIPVYSTLYGRELTAGELMDAGYWT
                     EHARNPVRWADAMAAAQDRRTDFIMELGPRRVLGPMARRARQTTAEILTPCPGPAATGL
                     EPADVIARLARAGSRPTWDALYDADQQRLVRLTPYRFAADSRFWTTAGNDRPRAGGTTT
                     RPHHAEPSAPKQADIDDVHTAVLAILGDISGHRPTEISVAAHLGDELGFDSIMVVQLKA
                     QLERQFGIAIDAVELLAEIETSGDLITYLRRQPAHRRTVTR"
     aSDomain        20010..21245
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08080_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.10E-159"
                     /label="AS857_RS08080_PKS_KS.1"
                     /locus_tag="AS857_RS08080"
                     /protein_end="415"
                     /protein_start="3"
                     /score="522.9"
                     /tool="antismash"
                     /translation="IAIVGIDGRFPGAANPAEFWDLLMRGADAISTVPDDRWDPDALLG
                     SGRLNTTTGGFLTDPDVFDHEFFGISPKEAEAMDPQQRLMVQVAWRALEDACLDPRAQA
                     GTATAVFIGVMGNEWAHLHMTDYDRITPHLGSGNGYCMIANRLSYLLDLKGPSWAVDSA
                     CSSSLVAVHQACSALRLGECDQAIVGGVNIMMTPALNIFYTQAGLSAPDSACKPFSAEA
                     NGIVRGEAVAAVVLRRLADAEAAGLPIYGVITGSAVNQDGRSNGLTAPNRWSQEQVIRD
                     AYRKAGVGPEQIAAVEAHGTGTVLGDMIEANALGAVHGVDRPTPCGLGSLKGNIGHTEG
                     AAGISALIKMALAAHHGVVPSSRHADTENPQLALRAKGLRLLKAPQRLKGTAPLLAVSS
                     FGLGGTNAHLVLR"
     aSModule        20010..22877
                     /complete
                     /domains="nrpspksdomains_AS857_RS08080_PKS_KS.1"
                     /domains="nrpspksdomains_AS857_RS08080_PKS_AT.1"
                     /domains="nrpspksdomains_AS857_RS08080_PP-binding.1"
                     /locus_tags="AS857_RS08080"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     misc_feature    20136..20138
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       20472..20519
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08080_0001"
                     /evalue="7.80E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="AS857_RS08080"
                     /protein_end="173"
                     /protein_start="157"
                     /score="18.0"
                     /tool="antismash"
                     /translation="GPSWAVDSACSSSLVA"
     CDS_motif       20661..20699
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08080_0002"
                     /evalue="1.20E-02"
                     /label="PKSI-KS_m4"
                     /locus_tag="AS857_RS08080"
                     /protein_end="233"
                     /protein_start="220"
                     /score="9.1"
                     /tool="antismash"
                     /translation="FSAEANGIVRGEA"
     CDS_motif       20895..20939
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08080_0003"
                     /evalue="8.90E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="AS857_RS08080"
                     /protein_end="313"
                     /protein_start="298"
                     /score="11.7"
                     /tool="antismash"
                     /translation="VEAHGTGTVLGDMIE"
     CDS_motif       20994..21038
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08080_0004"
                     /evalue="3.60E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="AS857_RS08080"
                     /protein_end="346"
                     /protein_start="331"
                     /score="10.1"
                     /tool="antismash"
                     /translation="GSLKGNIGHTEGAAG"
     aSDomain        21552..22394
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08080_PKS_AT.1"
                     /evalue="3.20E-92"
                     /label="AS857_RS08080_PKS_AT.1"
                     /locus_tag="AS857_RS08080"
                     /protein_end="798"
                     /protein_start="517"
                     /score="301.0"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSPYPGMTRALHDRFAGYRQALADVDQAMAEHLGRSVSSV
                     ILGEEPLIQQTGLAQPAIFAVGYAMSVMLSELGVQPDWLIGHSVGEFAAAVHAGVLALP
                     DACELVTARARLMQELPSGGGMLAVRGEPAEVLDLLDGTVGIAALNGPEDTVCSGPVDE
                     LERIAKTLQERGITTRTLDVSHAFHSPLMEPMLAEFAAVAVKFTYRPATIPVYSTLYGR
                     ELTAGELMDAGYWTEHARNPVRWADAMAAAQDRRTDFIMELGPRRVLGPMARRARQTTA
                     "
     CDS_motif       21555..21602
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08080_0005"
                     /evalue="5.00E-05"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="AS857_RS08080"
                     /protein_end="534"
                     /protein_start="518"
                     /score="16.0"
                     /tool="antismash"
                     /translation="FTGQGSPYPGMTRALH"
     CDS_motif       21729..21761
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08080_0006"
                     /evalue="4.20E-03"
                     /label="PKSI-AT-M_m2"
                     /locus_tag="AS857_RS08080"
                     /protein_end="587"
                     /protein_start="576"
                     /score="10.2"
                     /tool="antismash"
                     /translation="QPAIFAVGYAM"
     CDS_motif       21783..21905
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08080_0007"
                     /evalue="2.20E-23"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="AS857_RS08080"
                     /protein_end="635"
                     /protein_start="594"
                     /score="74.5"
                     /tool="antismash"
                     /translation="GVQPDWLIGHSVGEFAAAVHAGVLALPDACELVTARARLMQ"
     CDS_motif       21990..22028
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08080_0008"
                     /evalue="1.50E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="AS857_RS08080"
                     /protein_end="676"
                     /protein_start="663"
                     /score="11.8"
                     /tool="antismash"
                     /translation="AALNGPEDTVCSG"
     CDS_motif       22251..22283
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08080_0009"
                     /evalue="4.20E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="AS857_RS08080"
                     /protein_end="761"
                     /protein_start="750"
                     /score="10.7"
                     /tool="antismash"
                     /translation="YWTEHARNPVR"
     aSDomain        22674..22877
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08080_PP-binding.1"
                     /evalue="7.50E-14"
                     /label="AS857_RS08080_PP-binding.1"
                     /locus_tag="AS857_RS08080"
                     /protein_end="959"
                     /protein_start="891"
                     /score="43.8"
                     /tool="antismash"
                     /translation="AVLAILGDISGHRPTEISVAAHLGDELGFDSIMVVQLKAQLERQF
                     GIAIDAVELLAEIETSGDLITYL"
     gene            22922..23944
                     /locus_tag="AS857_RS08085"
     CDS             22922..23944
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084: 3-oxoacyl-(acyl carrier protein) synthase III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013003871.1"
                     /locus_tag="AS857_RS08085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3-oxoacyl-ACP synthase III family protein"
                     /protein_id="WP_058042449.1"
                     /sec_met_domain="fabH (E-value: 7.6e-37, bitscore: 124.3,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPTSYIRAVGTALPGAPIDNSALARRIGVSAEWIDMFIGTRTR
                     HFAIDLDTGEQTSTLAELAERAGAQAMQQAGITASEIDFLVLATATPDELMPATVNQVA
                     DRLGIDQVPTYQLQSGCAGAVQALDLGCLLLQRPEHEIGLVIGGDVCAKHLRLNREFGT
                     LPSAELVNYVLFGDGAGAVAVARERPTAGMAIRTVLNQVTGRGQRPGQMIRWFGEADRE
                     RGGQAVDEDYKAIEERVPTMAKEILWQLLDDAGWQAEDLAYLLPPQLSGRMTERIVSGL
                     GMPGATEVSCVADTGNNGNALPFLQLDRLAGMLSPGERALAISVESSKWIKAGFAVEGV
                     "
     gene            23956..25836
                     /locus_tag="AS857_RS08090"
     CDS             23956..25836
                     /NRPS_PKS="Domain: FkbH (265-408). E-value: 1e-36. Score:
                     117.9. Matches aSDomain:
                     nrpspksdomains_AS857_RS08090_FkbH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1256: FkbH like protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01686.1"
                     /locus_tag="AS857_RS08090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAD-IIIC family phosphatase"
                     /protein_id="WP_063804283.1"
                     /transl_table=11
                     /translation="MTTDADQAWDRLRLLRDNGRLAIAYAEAGTLAGSLPERRQAALGQ
                     LLLGLDPNVVTASDPMVTALNVVITGNGTTAPLQAPLAAAFARNQLLLRPRGQGQYVND
                     LGDPGSDVYSEQTDLTVCLLDPDLIASELAAVWTAADCERVLRSAGDRIRALAAEHDRA
                     GTGTLVLTTVPLPAWLAKQLVDFQSRARLSLAWREFNADLLRLAAELSRCIVLDLDVLL
                     TAPVSLDEPRMRVYTQVGYSEELLCRIADEIAAVARALCGRTKKVLVLDLDGTLWGGVL
                     GDDGVAGVQIGPTGPGDAFRRFQRTVAQLGSQGVLLAVCSKNDEHLVRAALAERAEMEL
                     REEDFVAIVANWEPKDRGIAGLAEVLNLGVDSMVFVDDSAFECGLVGEHLPQVAVVEVD
                     REPTRHVEQLLAGDWFAALRLTGEDRARRNSYQAEVQRDSLRSTSSSLQEYLNGLGTRV
                     EIFSPDEQDQSRIAQLTQRTNQFNMATVRMDLAQVQAALSGPGSDVWAVRSGDRFGEAG
                     IVGVVFHRIADDQLHIDNMLLSCRVFGRGLESAMVREVLAHAAELRVDRVVARYRPTPK
                     NGRFAQFYEEHGFVVAETDGDTTVWVHDLAELPSPLTHLAVTNLLRRPTP"
     aSDomain        24751..25179
                     /aSDomain="FkbH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08090_FkbH.1"
                     /evalue="1.00E-36"
                     /label="AS857_RS08090_FkbH.1"
                     /locus_tag="AS857_RS08090"
                     /protein_end="408"
                     /protein_start="265"
                     /score="117.9"
                     /tool="antismash"
                     /translation="KVLVLDLDGTLWGGVLGDDGVAGVQIGPTGPGDAFRRFQRTVAQL
                     GSQGVLLAVCSKNDEHLVRAALAERAEMELREEDFVAIVANWEPKDRGIAGLAEVLNLG
                     VDSMVFVDDSAFECGLVGEHLPQVAVVEVDREPTRHVEQ"
     gene            25833..26060
                     /locus_tag="AS857_RS08095"
     CDS             25833..26060
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018522891.1"
                     /locus_tag="AS857_RS08095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_058042451.1"
                     /sec_met_domain="PP-binding (E-value: 4.4e-05, bitscore:
                     21.0, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEAEFLTLLDEDLGLRLSVEDLSRDVDTLLHWDSMHLVRLLSVL
                     ERRTGKSIALNSLLEARTLNQARKLVMADA"
     gene            26113..26799
                     /locus_tag="AS857_RS08100"
     CDS             26113..26799
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984790.1"
                     /locus_tag="AS857_RS08100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="2-oxo acid dehydrogenase subunit E2"
                     /protein_id="WP_245699683.1"
                     /transl_table=11
                     /translation="MAPVFLDTDVDFTEVIAHRKRASEEGARYSYLSYVLRSATRVLEK
                     HPDCNAALGGGVLPKLAHFSAVRPKIAMDRTLSGQRVVLSAVLPDLRGAGLDEIQRAIA
                     RIRDTPVGKLPELRGTVMLHRLPALFGWPAFRAGMAALGKRPQLMGTLAVSSLGHRAVN
                     GFHATGGTAITLGLGQVKPTPVARENEVVIAPVMRLNLCFDHRVVDGAEAADVLDEIKT
                     DLENTS"
     gene            26796..28043
                     /locus_tag="AS857_RS08105"
     CDS             26796..28043
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013003902.1"
                     /locus_tag="AS857_RS08105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_058042453.1"
                     /transl_table=11
                     /translation="MTEQITAQACVIGGGPAGLVFALALAARGRDVIVVEKSEDFDRSF
                     RGESILPDSVWLLDQLELLQPLRDQKVLEAHGLEISENGRPVLRVDFRQFDQPQPFPME
                     IPQPMLLRVIADAASKHPGFRIIRPAKAVVLLRDGGRVTGVRCRTPQGDLEITSPITIG
                     ADGRYSKIRDMAGIEHHKTPLERDVLWFKMPYPQAWEPNRYRIRINQDRHAVFLPTHPD
                     MVRVGLNIPKGGLKDLRTAGIGALYARMDELAPELGSLVRKNITSWSGTMMLDIFTTVV
                     PQWSIPGLVLAGDAAHTLSPILGHGVNHAIMDALVLARLVDQALTGPDTATALDRAGTR
                     FQLVREGKVRQARDLQLRQEKIFTLSSPLATLTRRSLYRMINALPPVKQRVLGRAYFTI
                     PQVADPVAKQLQDVGA"
     misc_feature    27477..27479
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            28040..29164
                     /locus_tag="AS857_RS08110"
     CDS             28040..29164
                     /NRPS_PKS="Domain: Abhydrolase_1 (137-261). E-value:
                     5.9e-13. Score: 40.9. Matches aSDomain:
                     nrpspksdomains_AS857_RS08110_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF018234.4"
                     /locus_tag="AS857_RS08110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_058042454.1"
                     /sec_met_domain="PF00561 (E-value: 8e-09, bitscore: 32.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVSGAEHRGDADDLTELKKLVLLHAQAQGIPPADCAQLLWSIT
                     SDGAGSAGSWVDVWSSAAKRHLTAGDYLLACRHYNMARFPFVDGPERDAALRECVNAFQ
                     RWATTRQITREEVVVGGDRMPFWLSTSPRGRAAPALIVVGGIVSIKEQWGELLPMARRL
                     GMTVACAELPGVGESNVPYDRNAWRIFPALLDRLAELRGISEAYVLAMSFGGNLAIRAA
                     ARDERLRGICTVGAPISKFFTDRQWWSQLPGTTLRTLAHLTGHPVDELQERIADWALTD
                     AELSQVDIPVRYVASRRDEIIPATDPARVRRHIRDGEVLEHDDVHGSPQHLLETRLWLV
                     RSLLSMRGATVVPAVLGLALNLLGLQNRIRGGLR"
     aSDomain        28451..28822
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08110_Abhydrolase_1.1"
                     /evalue="5.90E-13"
                     /label="AS857_RS08110_Abhydrolase_1.1"
                     /locus_tag="AS857_RS08110"
                     /protein_end="261"
                     /protein_start="137"
                     /score="40.9"
                     /tool="antismash"
                     /translation="PALIVVGGIVSIKEQWGELLPMARRLGMTVACAELPGVGESNVPY
                     DRNAWRIFPALLDRLAELRGISEAYVLAMSFGGNLAIRAAARDERLRGICTVGAPISKF
                     FTDRQWWSQLPGTTLRTLAH"
     gene            29161..29919
                     /locus_tag="AS857_RS08115"
     CDS             29161..29919
                     /NRPS_PKS="Domain: Thioesterase (16-240). E-value: 4.7e-44.
                     Score: 143.4. Matches aSDomain:
                     nrpspksdomains_AS857_RS08115_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1004: thioesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013166.4"
                     /locus_tag="AS857_RS08115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_107105535.1"
                     /sec_met_domain="Thioesterase (E-value: 1.4e-40, bitscore:
                     136.9, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.8e-14, bitscore:
                     52.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTFYLGVPVDPASELRMYCFHHAGGGPSLFRGWQRALAPEVQVLP
                     VLLPGRDRRIREPRFTDIDRLVKELDRELGPSLEQPYVLFGHSMGALIAHRLAAYRSTA
                     GGRLPEAVILSGCRPPHLPSGLPPADRVSEAKLVSWLNEVGGLPDELLQRPEWLALLLP
                     ILVDDLTLCASAAQQPFTRLPCPVHVFGGDEDPLAGSHELSAWRTHADAEFTVTTCSGG
                     HFYLKDSPAQLLAHLRKALCRYRSPLRTSS"
     aSDomain        29209..29880
                     /ASF="active site serine inconclusive"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS08115_Thioesterase.1"
                     /evalue="4.70E-44"
                     /label="AS857_RS08115_Thioesterase.1"
                     /locus_tag="AS857_RS08115"
                     /protein_end="240"
                     /protein_start="16"
                     /score="143.4"
                     /tool="antismash"
                     /translation="MYCFHHAGGGPSLFRGWQRALAPEVQVLPVLLPGRDRRIREPRFT
                     DIDRLVKELDRELGPSLEQPYVLFGHSMGALIAHRLAAYRSTAGGRLPEAVILSGCRPP
                     HLPSGLPPADRVSEAKLVSWLNEVGGLPDELLQRPEWLALLLPILVDDLTLCASAAQQP
                     FTRLPCPVHVFGGDEDPLAGSHELSAWRTHADAEFTVTTCSGGHFYLKDSPAQLLAHLR
                     KA"
     CDS_motif       29395..29457
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AS857_RS08115_0001"
                     /evalue="4.10E-08"
                     /label="NRPS-te1"
                     /locus_tag="AS857_RS08115"
                     /protein_end="99"
                     /protein_start="78"
                     /score="25.7"
                     /tool="antismash"
                     /translation="EQPYVLFGHSMGALIAHRLAA"
     misc_feature    29939..29953
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.6"
                     /tool="antismash"
     gene            29959..31167
                     /locus_tag="AS857_RS08120"
     CDS             29959..31167
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003958937.1"
                     /locus_tag="AS857_RS08120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_058042455.1"
                     /sec_met_domain="p450 (E-value: 7.8e-23, bitscore: 78.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTADIRQTEARSFPFGREHVTKLPSIYGQLRASEPVSAILLPSG
                     DTGYLVSRYDDARLVLSDPRFSRAATIAPGAPRLTPVDFPAGSLFTLDPPEHTRLRKLV
                     AGAFTERRVQSLLPRIQQITDELLNACDTVGEEVELNQALAFPLPIMVICELLGVPHEE
                     RERFRVWSDAVVSLTAHTADQVVARQREMAGYMANLIERKRVEGGDDLLSALITAHDEQ
                     GALGTNELIVMAMTLLVAGHETTVSMIGTSVLTLLRHPETVHRLLEDEGYVAPLVEELL
                     RLNPIGDGGPLRIALEDVEMAGVVIPKGSAVMAAIGSANMDSSRFEQPEALTAEREVNP
                     HLAFGHGIHRCLGAALARAELRIAIRSLFMRFPTLRLAKPIDELRMKPGLLVNSLESLP
                     VTW"
     gene            31220..31663
                     /locus_tag="AS857_RS36705"
     CDS             31220..31663
                     /NRPS_PKS="Domain: Polyketide_cyc2 (3-140). E-value:
                     4.6e-14. Score: 45.0. Matches aSDomain:
                     nrpspksdomains_AS857_RS36705_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022072.4"
                     /locus_tag="AS857_RS36705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC domain-containing protein"
                     /protein_id="WP_063278416.1"
                     /transl_table=11
                     /translation="MRIVETNVTISAPASLVWDTLVGFDSYAEWNPFMVKAAGRAEPGE
                     RLAITLRQSDTRTMSFKPKVLVAEPGRHLRWIGRLLVPGIFDGMHEFILTETSEGTLLD
                     HKETFTGVLPALMGSKLDSTALGFEQFNQALKRRAEFRHSATS"
     aSDomain        31229..31639
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS36705_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.60E-14"
                     /label="AS857_RS36705_Polyketide_cyc2.1"
                     /locus_tag="AS857_RS36705"
                     /protein_end="140"
                     /protein_start="3"
                     /score="45.0"
                     /tool="antismash"
                     /translation="VETNVTISAPASLVWDTLVGFDSYAEWNPFMVKAAGRAEPGERLA
                     ITLRQSDTRTMSFKPKVLVAEPGRHLRWIGRLLVPGIFDGMHEFILTETSEGTLLDHKE
                     TFTGVLPALMGSKLDSTALGFEQFNQALKRRAE"
     gene            complement(<31862..33045)
                     /locus_tag="AS857_RS08125"
                     /pseudo=""
     CDS             complement(<31862..33045)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1237: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004004299.1"
                     /locus_tag="AS857_RS08125"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS110 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MYDISDVDVFFALDVGKTAHHGHGLTPADKKVFDKPLPNSEPKLR
                     AVFDKLTAKFGTVLLIVDQPASIGALPLTVARDAGCQVAYLPGLAMRRIADLYPGEAKS
                     DAKDAAVIADAARTMPHTLRSLELSDEITAELTVLVGFDQDLAAEATRTTNRIRGLLTQ
                     FHPSLERVLGPRLDHPAVIWLLERYGSPAALRKAGRRRPAEAIRPKAPRMAKRLIDEVF
                     DTLDEQTVVVRGLAPWTSSSRRWPARSAPFTTSAGPWKPRSANCWRPTLFTRS"
     misc_feature    complement(33022..33036)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            33424..34252
                     /locus_tag="AS857_RS37370"
                     /pseudo=""
     CDS             33424..34252
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611187.1"
                     /locus_tag="AS857_RS37370"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="IS5 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGASERNPQPWVVDDELWLRIEPLLPSSPRGHRQPGRKRVLEDRQ
                     VLHGILFVLYTGIQWEWLPQELGFGSGMTCWRRLRDWNDAGVWQRLHEVLLDELRPAAW
                     TCRGR"
     misc_feature    33493..33495
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            34673..34930
                     /locus_tag="AS857_RS39495"
     CDS             34673..34930
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AS857_RS39495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_144440757.1"
                     /transl_table=11
                     /translation="MPTKAAISLRHDLEPGSLYLRDSTHELHLLRPFLTGEVCPVCRAW
                     STFHADLVPKGGVQLKSLEHGHVLHQPAGKSKALVDVGLL"
     gene            <35103..>35369
                     /locus_tag="AS857_RS37375"
                     /pseudo=""
     CDS             35103..>35369
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019064871.1"
                     /locus_tag="AS857_RS37375"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPMTMQAGDLGLAITKVRTRSFFPSLLECRRRIDRALYPMLMETV
                     STGSVDGLVKGLGGDTGISKSAVARVCQDLDTELSVFRPRPLDH"
     gene            35640..38270
                     /locus_tag="AS857_RS41145"
     CDS             35640..38270
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AS857_RS41145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_245699685.1"
                     /transl_table=11
                     /translation="MDLNSLRKLVEGQLLRFEGNAFQDCMDRFGLEMYPGDYQPVRAAG
                     PKGDTKNDGYCPKARVFFAAHATRAERIDRTKAKIRSDLAGCLKEHRDVKVWRFLTNDT
                     LPGEVDQFVDNELRPLYASVTIEVWGLRTLANEICRLTRLQVDRVLDVNTDTERWPAPN
                     GDSGRGDRAVYSGRPVEELTDPHALEVHKPIVVQNAPIGLPVYIARSHDVVLRQELASP
                     GSALVVLVGGSSSGKTRAAYEAVRSMSGWMLHHPIFPSRSSALIEVLQSESVAPQTIIW
                     LNELQDYLMTDTGEVAASAIRKALLSHRDVKFVATIWPRYWQDITDPGRPFPGGRELLA
                     NQAIRVDIDTEFRGDLLVSAAQSDMRFKMALASSPTRVTQYLAAGPALLDFFKDCKDRN
                     PGAWAVLCAAMDGHIAGHPQFATSGFLADAAPGYLTDEEWGAVGDDWFEGALACVTAEL
                     RGAIRPLARIRPRGGRSSGVYYRLADYLVQYSQQERRESPVPRSFWDAVLQHAGDPVAA
                     SVFARAAGDRGMHKEAAELWMPLALDGDSGALHELLQNPTVTSEDILPLAHAAIDAISL
                     CDTMGLGWMLIEFYHHESLKARLVDRISRSPHDLRIGPPIDMGQILEELDAAHHGEAVR
                     VYSQTIRSQLASIDASDFWSFSALSGALLRSEVWEANEVGRALARSYFLGRKMEVTNLA
                     YFLAHLTGHLDSDAEFIDEVRAELNSRIDEVDVTEVISLHPAIVNLFNAGEDELGNILI
                     ARASEAVDTMILGSSYAPLELMELLYGRGDLDTLKHLALRIAKDFDPMLSHAALTSLIR
                     LRKVECHEAFAIMAKRMATTGPVLPVAGAEDLVTFYERTGLAELRDAYATRLLNFRRHE
                     GAGTV"
     misc_feature    36183..36185
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            38472..38630
                     /locus_tag="AS857_RS40605"
     CDS             38472..38630
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AS857_RS40605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_216823960.1"
                     /transl_table=11
                     /translation="MTVEQLAADFGVHAMTLWKWMRRADIDDGAKPGTSSQESVEPRET
                     RRWIKRP"
     gene            <38609..38968
                     /locus_tag="AS857_RS41150"
                     /pseudo=""
     CDS             <38609..38968
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611781.1"
                     /locus_tag="AS857_RS41150"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="SVDQAALNNAVARRDNVAG"
     gene            39273..40484
                     /locus_tag="AS857_RS08150"
     CDS             39273..40484
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018533081.1"
                     /locus_tag="AS857_RS08150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="WP_245699687.1"
                     /transl_table=11
                     /translation="MNILSQPIKKLPPNAKGQVRYRFVVDVGTDPATGKRKQLTRTLGT
                     LREAKAEYARITVRRHEGALVPRNKMTVNEWLDQWLAKKAEDLEETTISTYRVTLDRVR
                     GRLGHIRLQELTEDDAEAWMLWALREGRVRATKAGPGLGVTSVEMSLTRLKEALNRAVA
                     RRLVAVNVAQEVRIPRKVCKAERQAKAEVPPWSVAEVHAFVRAVRDHRLYAPLCLSLMG
                     LRPAEVCGMRWADLDLEPATLAVANTRTLMGNKTVVEKDTKSLTGERDLPLPVLVKEAL
                     RSFKGTQAAEKRAAGQAYEDSGYVLLDELGTPLNVRQLREQAYKVMAENALRRVRLYDA
                     CASCFTYLANNGVPDHLLARWAGHTDVRTTKRWYVKPDVEDLRAAANAWSGLTGLPTPV
                     VREV"
     gene            40505..>41281
                     /locus_tag="AS857_RS42055"
                     /pseudo=""
     CDS             40505..>41281
                     /NRPS_PKS="Domain: Abhydrolase_1 (18-117). E-value:
                     1.8e-17. Score: 55.7. Matches aSDomain:
                     nrpspksdomains_AS857_RS42055_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983408.1"
                     /locus_tag="AS857_RS42055"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /pseudo=""
                     /sec_met_domain="PF00561 (E-value: 1.6e-13, bitscore: 47.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.8e-13, bitscore:
                     46.8, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSETTKTLQHRFDGPEDAPVLVLGPSLGTTWHMWDRQIPELTRHW
                     RVLRFDLPGHGGAPAAPAATVDDLGDRLVATLDSLGVDRFGYAGCSLSAAVGIDLALRH
                     PHRLASLALVAASARYGTADSWRQRGAGVRRDGLDPVARSAPERWFTANFSGAQPAIVD
                     WAVQMVGTTDTYSYIAACDALAAFDVRAELTRISVPTLVIVGAEDTTTPPADARVLVAG
                     IHDAKLAVVPGASHLAPVEQPSAVTDLLVRHFTTAWQ"
     aSDomain        40559..40855
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS42055_Abhydrolase_1.1"
                     /evalue="1.80E-17"
                     /label="AS857_RS42055_Abhydrolase_1.1"
                     /locus_tag="AS857_RS42055"
                     /protein_end="117"
                     /protein_start="18"
                     /score="55.7"
                     /tool="antismash"
                     /translation="PVLVLGPSLGTTWHMWDRQIPELTRHWRVLRFDLPGHGGAPAAPA
                     ATVDDLGDRLVATLDSLGVDRFGYAGCSLSAAVGIDLALRHPHRLASLALVAAS"
     gene            <42110..42463
                     /locus_tag="AS857_RS42060"
                     /pseudo=""
     CDS             <42110..42463
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090402.1"
                     /locus_tag="AS857_RS42060"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="ERGERIRREVLGDEPVDRDGFTGDFHDLVTRSAWGGAWSRPGLDR
                     RTRALITLTALTARGHVDEIAPYTRGALRSGVTPDEIKETLLHTAVYCGLPAAGAAFAA
                     AQRVIAEEAGSGA"
ORIGIN
        1 ttcaagggca acgcgacgca gaacttctgg cgcgccgccg agaacctctc cgtcaccccc
       61 gcctccggcg ccgaccgctg ggccgtctcc caggccgccc cgtaccgccg catgcacctg
      121 cgcggcgacc tccgcctgga cgacggcggc tggtcgagcg gcgggttcac cgccgactcg
      181 ctgatcgacg ggcgggtgct ctcgggaacc cagcagcagt ggctcacgcg caacagcgag
      241 ctccgcggcg gctggtccgg cgccacctgg aacatggtgt tcgccggggt gcggggcgcc
      301 ccgccgacga ccttccccga cccgccccgc accagcgtcg agcgcacccc cgccgtccgc
      361 gagaagccct tcctgcacat cgaccggtcg ggcgcctacc gcgtcttcgt ccccgccctg
      421 cgcagggccg cccggggcac cacctggtcc ggcggggcgg ccgggcccgg cgcctcccgc
      481 ccgctcggcc gcttcttcgt cgtccggccg ggcaccggag ccgcccggat caacgaggcg
      541 ctcgcgcggg gcagggacct gctgatcacg cccggcgtcc accacctcga ccggcccctg
      601 cgcgttaccc gccccggcac cgtcgtcctc ggcctggggc tcgccacgct cgtgcccgac
      661 cggggcaccg ccgcactgac cgtcgccgac gtcgacggcg tccgcatcgc gggcctgctc
      721 gtcgacgcgg ggcgcgcggc gtcgccggtg ctgatggaga tcggcccgcc cggcgcccgg
      781 cgccgccacg ccgccgaccc cgtctcgctg cacgacgtct tcttccgcat cggcggcgcc
      841 ggtcccggac gggccgtcag gagcctggcg gtgcacagct cggacgtgat cggcgacaac
      901 ctgtggctgt ggcgcgccga ccacggcagc ggcgtcggat ggaccgtcaa caccgccgcc
      961 gaggggctgg tcgtcgacgg cgaggacgtc acggtgtacg gcctgttcgt ggagcactac
     1021 cagcggcagc agacgctgtg gaacggcgag ggcggccgca cgtacttctt ccagaacgag
     1081 ctgccctacg acccgcccgg ccgcgccgcc tggggcgacg gccgggccac gggctacccc
     1141 gcctaccggg tcgccccctc cgtgacccgc cacgaggcct ggggcctggg cagctactgc
     1201 cacttcacgg ccgcgcccgg gctcgcggcc gaccgcgcct tcgcggcgcc ccgcaggccc
     1261 ggagtgcgcc tgcacagcct cgttgccgtc tcgctcgacg gcggctgcac gctgcgtcac
     1321 gtcgtcaacg acaccggagg gccggccggc gccgggaccc gggtcgcgac gctccgctcc
     1381 tggccggagg tcgaacgact gtccggaaaa cgcccttgag tcgatcactc tccgcaatcc
     1441 atgatgatct tccggagcga ggggggacgc catgggagcg gccgaagcaa aggcgatcgt
     1501 cgatctggag gccatggggg aggagttcgc ccggcatccg caccgggtct acgccggcct
     1561 gcgcgaacag ggccccgtgc accgcgtgcg catgcccgag ggcgccgagg cctggctcgt
     1621 cgtcggctac gacgaggtgc gcgccacgct caacgacccc cggctgacca aggactgggc
     1681 gaagtccagc tcggacatca gcctgatccg ggcctccgtc gggccgaaca tgctcgtcct
     1741 ggacgcaccg gaccacaccc ggctgcgcaa gctcgtcgcc agggagttca cgccgcggcg
     1801 cgtcgagggg atggcgcccc gcgtacagca gatgacggac gagctgctcg acgccatgct
     1861 ggcggcgccg ggccgccgcg cggacctggt ggaggccctg tccttcccgc tgcccatggg
     1921 cgtcatctgc gacctcctcg gcgtgcccga cctcgaccgc gaggccttcc gccactggtc
     1981 gaacatcggc gtcggcgcgg gcccggccga ggagaaggcg accgccgccc gtgaggtcac
     2041 cgcctatctg aacgcgctca tcgccgccaa gcgccgggag cccggcgacg acctgatgag
     2101 cgccctgatc agcgccgcgg acgagggcgg cgaccggctc tcgcccgagg agctcctcgg
     2161 cacggcctgg ctgctgctcg tcgccggcca cgagaccacg gtcaacctga tctcgaacgg
     2221 cgtcctcgcc ctcctgcagc accccgacca gctggccgcc ctgcgcgccg accccggcct
     2281 gctggacaac gccgtcgagg agatgctgcg ttacgacggg ccgctggaga cccccacgta
     2341 ccgcttcacc accgagcccc tggagatcgg cggcacgctc atacccggcg ggggcgagct
     2401 cgtgctgccc gtgctggccg acgccgaccg cgatccggcc cgcttcccgg acgccggccg
     2461 gttcgacatc cgccgcgacg cccgcggcca cgtggccttc ggccacggca tccactactg
     2521 cctcggcgcc ccgctggccc gcctcgaggc ccgggccgcc atcggctccc tgctggagcg
     2581 ctgcccggat ctcgccctgg acgcccaccc ggactccctc acctggcgcg aggggctcct
     2641 catcaggggc ccgcaccggc tgcccgtccg cttctgagga tgcccggccg ccctgcggcc
     2701 tcaggcgggc ggcgggtgcc ccagctcgtc gcgggcgcgc tccagttcgg cgcgggcccg
     2761 ctgccgggcg acggggctcg cccccggctg gtgcctcagg aaggactcga cgaatcctgc
     2821 gcgccgcgcg ggcgggtagc gctgctcggc caggaacggc aggtcgttgc cgaccatgct
     2881 gcgggcgacg agcagcgggg tgtcgctgtg cagcgggcgg aagccggggt tgtgcagccc
     2941 cggccccggg tgcccgggga agaactcgcc gagcatcatc ccctccgcca cgaactccgg
     3001 tttgagccgg tcgtggacgc ggaccacggt cgcggccgcc accccgggca ggaccaggac
     3061 tatggtcttg tcgatggtgt gctggccgct gtgcggctcc atggccagcc agtgcgcctt
     3121 gagcgcggcg acggcggcca cgagcccggc ctcgtcgcgc accggcggct cggcgagcgc
     3181 gtagcggatc agcccgagcc gctgcgagag cggcacgaac gggcagaccg ccccacggcg
     3241 gccgaggtcg gggtggggcc gggcgacgtg tccggagatc cattcgtgga cgggccgcag
     3301 cagttcctcc gcggcggcct cccgctggtc gtagagccgg atgcgcgcga ggccggagtc
     3361 cgccccgccg ccgtccggga gggtgcagtg atcgtttccg tggttcatgg gttgtccccc
     3421 cgtcacggtc tcttgtcagt aggaaaaacc caccggaccg ggatcgaggt tgagcgatcg
     3481 gggcaaaata gctttattgc acccctagcg ggcggtcgct gtgaccagaa gggctacgcc
     3541 gtcagtgcgg agccgaactc caccagcagt aaggccgagg ccgccagcag cagtacgccc
     3601 gagccgccga gcagcagccg gtagccgcgg gtgccgatcc ggtgccgcgc ccgggcgacc
     3661 acgacggcga gcgcggcctt gctgccgacc agcagcccgt agaagccgaa gaggaaaccg
     3721 ccggcgccgg gcggtccgtt gcgccaggcg gccacgagca gcggcgcccc cgtcgtcagc
     3781 cagaacatcc acgggtgcgg gctgaggagg ttgacgagcg cgccctgcca gagggtccgg
     3841 cgtccccgga cccgggcctc cgcggtgtcg cacgcctcgg gcacctcggc cgtacgggcc
     3901 tcgcgcaggg tcgagacggc cagccaggcg aggaagaggc cgccgagcac gccgccgccg
     3961 gcgatcgccc gctcgggcag cacggccagc acggtcacgg ccagcacgat caccggcagg
     4021 tcggtgagca ggggcaccgc cgccacgcgc agcccgacgc cgagcccgcc gcgcagggtc
     4081 cccgacagca ccagcgcgag cagcgggccc gggctgatcc ccgcgctgaa gccgagcgcc
     4141 acccccagag ccagctcttc cacggcgccg cccatctccc ctcaccggcc cccgcggggc
     4201 ataggtgaaa atcagtggat attcagtcac atcagtactg acatctgtat tgcacaagac
     4261 gcctgcaagg ggcacgaggt tgacgccgcg gtcactcgta tcggtaacgc cggatacgtg
     4321 ccgttacatg tccggacaac ctgacctacg aacttcccgt catccggtcc cgcggctagg
     4381 ctcccttcgt ggcgaaccaa ccacccctcc agttcagcct ggaccgcagc agccccgtcc
     4441 cgctctacta ccagctgtcc cagcagctcg aagcggcgat cgagcagggc gggctcgccc
     4501 ccggcagcct gctcggcaac gagatcgacc tcgccgcgcg gctcggcctg tcccggccca
     4561 ccgtccggca ggccatccag tcgctggtgg acaagggcct gctcatccgc cgccgcggcg
     4621 tcggtaccca ggtgctgcac agccaggtca agcgccccct ggagctcagc agcctctacg
     4681 acgacctcga agcggcgggc cagcaccccg ccacccgggt gctgcaccac gggaccgagg
     4741 ccgccgcggc gggcgtcgcc gcagccctcg gcgtgcccga gggcaccgag gtcctgcgga
     4801 tcgagcggct gcgcctcgcc cacggcgagc ccatggccca cctgtgcaac cacctgcccg
     4861 tgggcctcct cgacgccggc cccgcccgcc tggaggagac cggcctctac cgcctcatcc
     4921 gtgccgccgg catcacgctg cacagcgccc ggcagacgat cggcgcccgt gccgcgaccg
     4981 ccgaggaggg cgagcggctg gccgagccgg agggcgcgtc gctgctgacg atggagcgga
     5041 cgacgtacga cgacacgggg cgcgccgtcg agtacggttc gcacgtctac cgggcctcgc
     5101 gctactcctt cgagttccag ctgctggtcc gcccgtagcg gcccggctcc ggccccggcg
     5161 tcgtcggccc ggacggccct gccccgttac gtcatgccgt cagaatgttc ggacaaagtc
     5221 ttgacgcagt ggggcgcccg ccactagaac tccacccaca tgcagcagcc cccggcggta
     5281 cccgctgaag cccccgcggt cagcggtgac ggatggtgac ggatacttgg gcggttgggc
     5341 ccgtggaatc ggggtccggc cgcaccgtga cagacagtga gaagggcaac tcctcgtggc
     5401 aagggttcgg acaggcgtac gtgcggtgag cgccgtgctg gcagcggtgc tcggcgccac
     5461 cctggcgggg tgcagcgcta cgggcggcaa gcgcgcggag gagcgggcgg ccaaggccgc
     5521 ccagggccgc gccgcggtcg acacgccccg ctggaccttc gcgatggtca ctcactcggg
     5581 cgatggcgac accttctggg acatcgtcca gagcggcgcc aagcaggcgg ccgcgaagga
     5641 caacatcaaa ttcctctacg cccatgacgt ggagggcaac aagcaggccc agagcgtcca
     5701 ggccatgatc gaccagaagg tcgacggcct gatcgtcacg ctcgccaagc ccgacgccat
     5761 gaaggacgtc gtggccaagg ccaagaaggc cggcatcccg gtgatcaccg tgaactcggg
     5821 ctccgacaag tccaaggagt tcggcgcgct cacccacatc ggccaggacg aggtcatcgc
     5881 cggcgaggcc gtcggcgagc agctcaacga gcgcgggaag aagaaggcgg tctgcgtcct
     5941 gcacgagcag ggcaacgtcg gccacgagca gcgctgcgac ggcgtgaaga agtccttcaa
     6001 gggcgaggtg cagaacctct acgtcgaggg cacgaacatg cccagcgtgc agtcgtccat
     6061 cgaggcgaag ctgcagtccg acaaggacat cgacgccgtc gtcacgctcg gtgcaccctt
     6121 cgcccccacc gcggtcaagg ccgccgagca ggccggcagc aaggccgagg tcgacacctt
     6181 cgacctcaac gccaaggtcg ccgaggccct gcagtccggc aagctcggct tcgccgtcga
     6241 ccaggacccg tacctgcagg gctacgaggc cgtcgacctg ctgtggctct accgctacaa
     6301 ccgcgacatg ctcggcggcg gccgcccggt cctgaccggc ccgcagatcg tcaccaagga
     6361 cgacgccaag accctcgccg agtacgccaa gcggggcacg cgatgagcgc ccctgcaacg
     6421 gcccccgtcc aggacgcccc cgacgaacgg ctgatgcacc gctcgcacct gcgccggctg
     6481 ctcggccgcc ccgagctcgg tgcggtcgtc ggcgcggtgg cggtcttcgt cttcttctcg
     6541 gtcgtcgccg acagcttcct ccagacgtcg agcctgtcga cggtgctcta cgcctcctcg
     6601 accatcggca tcatggccgt gcccgtggcg ctgctgatga tcggcggcga gttcgacctg
     6661 tcggccggtg tgatggtgac cagcgccgcg ctggtctcct cgatgttcag ctaccagatg
     6721 acggccaacg tctgggccgg cgccggcgtc tcgctgctcg ccatgctcgc cgtcggcttc
     6781 ttcaacggct tcgtgctcac ccgcaccaag ctgcccagct tcatcatcac gctggccacc
     6841 ttcctgatgc tgaccggtct gaacctgggc ttcaccaagc tgatcggcgg caccgtctcc
     6901 accaagacca tcggggacat ggagggcttc gagtccgccc gcgcggtctt cgcctcgcac
     6961 ctgacgatcg gcggcgtgga cctccaggtc accatcctgt ggtggctcgg cctggtggcc
     7021 ctggccacct gggtcctgct gcgcacccgc gccggcaact ggatcttcgc ggtgggcggc
     7081 aactccgacg cggcccgcgc ggtcggcgtc cccgtcaagg gcaccaagat cgccctgtac
     7141 atggcggtcg ccttctgcgc ctggatctcc ggccagcacc tgctcatgtc gtacgacgtg
     7201 gtgcagtccg gcgagggcgt cggcaacgaa ctcctctaca tcatcgcggc cgtcatcggc
     7261 ggctgcctga tgaccggcgg ctacggctcc gccatcggct ccgcggtcgg cgcgttcatc
     7321 ttcggcatgg ccagcaaggg catcgtctac gcgcagtgga acccggactg gttcaagttc
     7381 ttcctcggcg cgatgctgct cctggcgacg ctgctgaacg cctgggtgcg caagagggcg
     7441 gaggcccgca aatgagtgct gctgccctgg tcaagctgac cgacgtcagc aagttctacg
     7501 ggaacatccg cgccctcgaa ggggtctccc tggaggtcca cgcgggcgag atcacctgtg
     7561 tgctcggcga caacggcgcc ggcaagtcca ccctgatcaa gatcgtcgcg ggtctgcacc
     7621 agcacgacgc cggcagcttc gagatcgagg gcgaggagac gaagctcgcc tccccccgcg
     7681 aggccctcga ccgcggcatc gccacggtct accaggacct cgcggtcgtc ccgctcatgc
     7741 cggtctggcg gaacttcttc ctcggctccg agccgacgaa gggcgccggc cccttcaagc
     7801 ggctcgacgt gcagcacatg cgcgagacca cccgcagcga gctgctgcgc atgggcatcg
     7861 acctgcggga cgtcgaccag cccatcggca ccctctccgg cggcgagcgg cagtgcgtgg
     7921 ccatcgcgcg ggcggtctac ttcggcgcga aggtgctcgt cctcgacgag ccgaccgcgg
     7981 cgctcggcgt caagcagtcg ggcgtggtcc tgaagtacgt ggccgcggcg cgcgacgccg
     8041 gcctgggcgt ggtgttgatc acccacaatc cgcaccacgc gtatctggtc ggtgaccgct
     8101 tcgtgctgct caagcgcggc tcgatggccg gcagccacgc caagtcggag atcggcctcg
     8161 acgagctcac ccgccagatg gcgggcggca gcgagctcga gcagctcagc cacgagctgc
     8221 agcgggcccc cggtccggac gtgatcggcg gcaaaccggt cgcctccggc gaggggtgac
     8281 acagctctca ccgagcgggc ccgccggtgg cgggcccgct tcccgcgatg cggtacgcaa
     8341 cgcttccttg aggcacaatc ggccacgacc gtatccacga ggcggagacc tcccgagacc
     8401 accgcaggga cgacgactct tgcgagcacg caaccggagc gaccgtagga ccgcacagct
     8461 ccacgccgtg gcggtggtgt catgagcatg tatcgcgacc tccaccgggg cgcggcgaag
     8521 gccaccgtgc tccggaccgt cggcacgcgc gagcgccgct cgcacctgac cgctccgcgc
     8581 gtccccaccg tcggcatcga catcggtggc accaaggtga tggcgggcgt cgtcgacgcc
     8641 gacggcacca tcctggagaa ggtccgcacc gagacgccgg acaagtccaa gagccccaag
     8701 gtcgtcgagg acaccatcgt cgagctggtc ctcgacctct ccgaccggca cgacgtccac
     8761 gccgtgggca tcggcgcggc cggctgggtc gacgccgacc gcaaccgcgt cctgttcgcc
     8821 ccgcacctgt cctggcgcaa cgagccgctg cgcgaccgcc tcgccggccg cctcgccgtc
     8881 cccgtcatgg tcgacaacga cgccaacacc gccgcctggg cggagtggcg cttcggcgcc
     8941 ggccgcggcg aggaccacct cgtcatgatc accctcggta cgggcatcgg cggcgcgatc
     9001 ctcgaggacg gccaggtcaa gcgcggcaag ttcggcgtcg ccggcgagtt cggccacatg
     9061 caggtcgtgc ccggcggcca ccgctgcccg tgcggcaacc gcggctgctg ggagcagtac
     9121 agctccggca acgccctggt gcgcgaggcc cgcgagctgg ccgccgccga gtcccccgtc
     9181 gcgtacggga tcatcgaccg cgtcggcggc aacatctccg agatcaccgg ccccctcatc
     9241 accgagctgg cccgctccgg cgacgccatg tgcgtcgagc tgctgcagga catcggccag
     9301 tggctcggcg tcggcatcgc caacctcgcc gccgccctcg acccctcctg cttcgtcatc
     9361 ggcggcggcg tcagcgccgc cgacgacctg ctgatcggcc ccgcccggga cgccttccgc
     9421 cgccacctca ccggccgcgg ctaccgcccc gaggcccgca tcgtcaaggc acagctcggc
     9481 cccgaggccg gcatggtcgg cgccgcggac ctggcccggc tcgtcgcccg ccgcttccgg
     9541 cgcgccaacc gccgccgcgt cgagcgctac gagcggtacg cgagggcggg gcgcgcttga
     9601 tgagcaccac ggagcacccc gagcgcaccg cgccgccgca cggccccggg cagccggacg
     9661 acggcttccg ccgccgctgc ctgaaggccg tcgtcgtctt cctgctcatc gccatccccg
     9721 ccggctacct ctacatctcc gcgatgcaga gccgcggcgg cagcgagtcc aagaaggagc
     9781 aggcggccgc gtccggcctg gaggagggct ggcccacccg gctccagcgc cgcctctacg
     9841 aggtgaccgt cccgccctac gcggaggacg tcgccagcta cgagaccaac gcgtggaagg
     9901 cgagctcgct cttcctgcag ttcacgacca cgcgcgagaa gttcgacaag tggctctccg
     9961 acgtcggcac cagcgcctcc gagctggagg acggcgaggt caccatcgac gaggacgagg
    10021 ccgccgaggt cggctgggac ctgggcggcg agcaccgctg ggcgggcacc accgtcgacc
    10081 aggacaagcc caagccctcc ctggaaatca ccgccaacct cgacgacccg aagtacccgc
    10141 gggtttttgt agtgtccacg accacgccct gatcgccctt ccgggccgtc ggatagcgtg
    10201 gcgcgggtga gtgagaagca gaccccgcag cccctccagt accggaccga cggccccgag
    10261 gacgggcccg tcctggtcgt cggccccgca ctcggcacca cctggcacag gtaggcggaa
    10321 gcgtctcttg gcgtccacgt ggtccagatc gctgccattc acgcaggtgg ggcctctgtg
    10381 gttcaggcgc gtcgatggtg ttggtgacac cgacgtgact cgtgatggtc acggagaccc
    10441 cctgccgggc cggtgctggc aggaggcctc ggcgctcctc agctgcgtgg tccgctcctc
    10501 gatcctgcca tggcgtctgc gaacgtctcg agtgccggta gcgggcggcg ccgccgctcg
    10561 gcccacccag gaatcagccg cggcctgaaa cggtacgcag ccaagaggtt tacctcctcg
    10621 tccagggaca gaaccaggac cgggtcgctc gtgagacggg gcagtcggcc gaaggctccg
    10681 gcaaggtact cgttgcacgg cggatcacga cggtgtgcag cacccggtgc tggtgccagt
    10741 tggactccgg atctccggtg tcgagcactc ggagcaaggg agctgtgacg atgcgccctc
    10801 taaggccgat gcgtagtgcg ccatgggaaa tctccgcgac gaactagccg cgccagcgtc
    10861 cgcggcgaga gaacgatctt ctggttgacg cgcaggagct ccgggttccg cagcaactgc
    10921 gcggtgcgct ctgtatgcac tcgcaccccc agacgcctgt cgtacctcgc acccagggcg
    10981 cggaaagcga gactgtgcgc ggtgcggcac tccacctttg atgggaagtg cttggccgcg
    11041 tccatagcga tggcccggtt gtacgccagg tacaggcacc ggcccctcac cccggcggcg
    11101 gccattttca gcgtggtcgt cttgccggtg ccggccccag cttccatgac tagtcctctc
    11161 cccggaggcc gtctcctcga cgatgcgctc ttgttctgag gtcggcgcgg gcccctcgcg
    11221 taccgcgcct ggccggtttg gctgtgtcgc tctccgcaga tgtcgtttcg acgtggtttc
    11281 gggagtcggc caccagaggg ccagcaagat caatgtcact gggttcggat gtcactccgg
    11341 cccttccgcg cgggccgatt gtggccgtcg ctcgccgccc gtccaggtcg ttcgtcctcg
    11401 cttcgctcgg gcgctcctgg acctgcggct tcgccgacgg caaaggcccg cagctatcga
    11461 ggaagggccc agaaggccgc gcgccgcggt ccagctcgcg gacggctccc ggagacgctg
    11521 acatcgcttt cggcctcaac gaggtgactc ccgctgtcat cgcgaaacga catccggggt
    11581 cacgtccata gccagccggt tggaccgcgc gtttggcggg ggcgccgaga cgactgccgc
    11641 cgctacgccc ccgctctgct gaacgaaggc caaagaatga gactgcggca cctgccagca
    11701 gggaccgtcg gactgatcgg actgctcaac cccgtcaccg gcgtccagct cggcacatct
    11761 gtcgccggag agacgttgac cgttcagcaa ctgtgcggac tggtcctgct tctggccgga
    11821 gtcgtcctgg gtcaacccaa gcctgccggc cgccgcgaca gaagtcaggt acctccccat
    11881 gcggtggccg acgagcgttc tgcgcaagca tcctctaagc gcgatgccct gtgaagatca
    11941 gagacgcggg cagagctccg gcacggatag gtgcgaggac gagtgaagtt ccgccgtctc
    12001 gccacacacc gctgatatcg aggatgtccg gctggattat ctcgtggatg tcggctggct
    12061 gcccggctcg ggttgaatcg acaggaagtt gttgaccaca gtggagcggt ggaaggcccg
    12121 gctgatctgg gcaaggaacc ttgcctcctg gttgaggtcg tcacggccag gcatgttcag
    12181 gcgcatggac tcgtcgggcg atgagtcacg gttcccggga gccaacacct ttcgcaggca
    12241 gcaagcgatc gctgtggctt ccacaagatc tttcccggtt acgcctgagc tcacaacgtg
    12301 ccggtgcgcg gtgtcgtaga gcctctggga gatacgcggt tgaagaaaca gcattccgtc
    12361 ccggatctcg atgaccctac ggtagagccg caggtgtgac tggcgcaggc cgacgagatc
    12421 ggcaagcgcg ccggactcgg aactatcgag gaccacctgg ggatactctc gctggaacgt
    12481 ccgccacagg ggggcaagcc tgcgaagcgt gaggcagcgc tgccacatgc gccagctgac
    12541 gttagttgct gggatgatcg agccgatggc catcagcagg atcgcgatcg cttgcagtga
    12601 gttcgcggcc ttcgccgcca gttcaactgg cacggcggcg ccggacgcca gtatggacag
    12661 taaggtgatc ttgtagacgg cgtagaccag gtccagtgcc gcgccgacgc tgatacacag
    12721 cagaccccag cgtagaaagg gctgggcggc cagtctgccc gcacgccaca gcagtgcagc
    12781 cacgctggcc agcccgatac cgatatacag ctcgagcgcc acccaatacg cgattgtccc
    12841 ccaggaaggt ggggatccgc tcagcagctg ttcgggagag tcatgaataa ttgtctccga
    12901 catgacaaac agcgcgcaca tcgtcagcag agtggcgcac gcagcaatca gccgggtgcg
    12961 aggattcctg gggttgcgca catcggcgcc ggtgattatc ccgacgaagc gcaaggcagt
    13021 gattgacgac aaaacgccga gaagatgttt cagcagcgtg gcgaggtctt cagtgcccgt
    13081 cgtccagtcg atgtagtctg ccaggctccc gttactgagg ctcctagcga ttgcccacaa
    13141 catgaatgtt gcccacagca ttcgctgctg cgggctacga aatgccgacg gaatgcgcca
    13201 gatagcgacg agccacagcg tgacctgaac ggcgatctcc acgaccaact agcctcgtga
    13261 agcgggggat tggttgctga acgcctgact caggtcgcgt agcaggagat ccttcctcgc
    13321 atcctcgttc aacagctgta ctcgtcccgc ctgttggcgg attagcgagg ccagcaactc
    13381 agcttcctgt tcctgctcgg tggagtagct cacccgaccc agcgcctggc gcacgactgc
    13441 cgggttcagg ttcggcatca gcctgctcag aacgtcgctg acattcggat cggtaaagct
    13501 gtgaccactg agcatgtggc tgagctcgtg caagatgata tgctccgagt gcagccttga
    13561 ggtgttgtct tcatagaaga tgtagtcggt ctcaccgatt gacagccaca tgccacacgg
    13621 cgttgtttcg cttaaccctc gcgtcggccg cagggagatg cgccgactcc gctggcctcc
    13681 aacatatgcg cagaactctg caatatcgaa cgggcttggg acccaaatgt cagcaaggag
    13741 tgcctcgcat cgcttgcgga cctcgcccat tccgggtttg cggaagcggc tgaggttcga
    13801 actccgaaat ttgctcaact tcatcacgac atccccgctg agagccccga acgccaagtc
    13861 ccgagtgccc cttctgagct agagcacata accagaccca gcggcaccgc cccccggccg
    13921 gcgcgtggtc atcgtcatat tacgtcacat ggtgggcact tttcaccggt tttccccacc
    13981 ctcaagctcc cagaacttgt tgatcatgct gctgaccgct tcccgactcc cagaggaaag
    14041 gtccgcggcg cgcatcgcaa tctcggtaac acctgcgtta cgaagagcgg cgagcagttg
    14101 aagctcgctg tcaatctcct cggtgatctt gtcatccagg aagtaagcga caggcacgcc
    14161 gaagaagttg gccaacccgg tgaggtgctg cagcgtcggg ttgtcccgcc tcccggtgcg
    14221 cagttgccag atgtaggtgt gggagatcga gatgccttgc tcttcacgga tggactctgc
    14281 cacggctgta tagctgcact cgccgtgctt ccgcttgccg gtggtagtga agagcctgtc
    14341 cagcttctcg gcgatggaga acgcctgtgc gggccgattg tccacgctgt ctccttggtc
    14401 cgcagctgac gttggcgggc accatgctaa cgcgtaggct gccgttgaca agtgtctcaa
    14461 cgtcagttta cgttcgacct gcctcgactc gggatcgagt tgacgtcagt gggtggcggg
    14521 tgagccgtcg gcggctcgca ggcagtcctg ggctgtccag tgtgggggtc gaagtgaacg
    14581 aacttgcgaa cagcagcttc acgcaccatg tccgtgaccg gctgctcgcc tatggcgatg
    14641 accggttcta cacgttcgtc aaggacgggg tggacggtct cgtcgaggac cgggtcagct
    14701 accgaggact ggacagcgcg gcgcggtctc tcgccgcgtg gttcacctcc tcggtacatg
    14761 ccggcaagcc agcactgctc ctcttccctg ctggccttga cttcctccag acattccttg
    14821 gttgtctgta cgccggagtc atcgctgtcc ctgctcctgt acccacggac ccgcgcagct
    14881 accggcgggt cgccaacatc gtggccgaca ccggtctgga actggtgctc accacctcgt
    14941 cgttgctcga cgagctacgc gaaaagctcc ccgagctgtc cgagacccgg ctcgacgtgc
    15001 gcgccgtcga ccaggactgc gcgggtacgg cggacgactg gcggatgccg tcgctcggcc
    15061 ttgaatccgt tgcattcctg cagtacacct ccggctccac cagtgaaccg aagggcgtaa
    15121 tggtcacgca ggggaacctg ctgcacaacg agggcgagat cgcttcccgg atgagcctgg
    15181 gcgatgagct ggtgatgaca ggttggctgc ctcatttcca cgacatgggc ctgatcggga
    15241 tgctgctgta cccgctctac gccggtggcg actgcacctt catggctccc ggaaccttcc
    15301 tcaagcggcc ggtgcgctgg ctgcaggtgg tctcccagac acgagccaac ctgaccgtgg
    15361 caccgaactt cgcctacgac atgtgcgtgc gcaccatcac cgacgagcaa ctgtctgcgc
    15421 tcgacctgtc ctccttgaag gctgtgctga acggcgcgga gccggtacgg gccaagaccc
    15481 tcgcggactt cagcgcccga ttcgcgcccg ccggattccg accggagatg ttcgtgccct
    15541 gctacgggat ggcggaggtg accctgctcg ccacttccgt cgacgtcggt gcacggcccc
    15601 aagtgaccaa agtggatcgg atggcgttgg agcgcgacga aatccggctc gatgacggtg
    15661 agcagtcgac cagcctggtc tcgtgcggag tgcccagcac gctggacatc cgcatcgtcg
    15721 agcccgcgac gcgtgtcgag cgcgcggtcg gccaggtcgg tgagatctgg ctccgtggcg
    15781 gcagcgtcgc tgccggatac tggaaccggc cggataccaa ccgtgagatt ttccaggccc
    15841 acaccgccga cggcgacgga cctttcctac gcaccgggga tctgggggta ctgctcgacg
    15901 gccagctcta cgtgaccggc aggctgaaag acgtgctgat cctgcgcggc cgcaatctgt
    15961 acccgcagga catcgagtac gtggtcagcg agctgcaccc ggcgctcgcg gcgggcaccg
    16021 gtgcggtgtt ctccgtccag gccgacggtg agcacgtggt cgtcctgcat gagatcaaga
    16081 gggggctgct cggcgagctg tccatggacg agctgtccgg aaggatcagc gttcacgtcg
    16141 cacggacctt cgacatccca gcaccgagcg tggtactgac caaccgggga gtcgtgcaaa
    16201 agaccaccag cggcaaagtg cagcgccggc tgatgcggga tctgttcctt tccaacgggg
    16261 tcaaggccct gcacgaatcg ttacgtccgg ccgtacacgg tctcaaagcc atcccggcga
    16321 cggctgaggg acagcgatga gcgttgcgat gacgtccctg gccgaggagt tcgaccatag
    16381 gctcggcgac ccccgtgctc ccgccgcaat tttctcctac gcacgctgca ctgagctgga
    16441 ccgagccgag gaattcccgg gggagatctg tgatctgctc aatgcattgg gattgcagca
    16501 gtactacgtg ccggagccaa ttggtgggaa gcttcgggac ttcccggtcc cactgcagtt
    16561 gatccgtgca gtcgcccgcc gagacctgac cgtggccatc gcacacggca agactttcct
    16621 gggcggtgtg agcgcatgga tctcacccgc atccgcggtg acccgcgcag tggcggacca
    16681 ggtaatcagc ggtgctcccg tcagctgggg gctgacggaa cgggcgcacg gcagcgatct
    16741 gatggcgggc gaggttcgcg cccaagaggt acctggcggc tatcggctca ccggggaaaa
    16801 gtggctgatc aataacgcca cgcgagggcg caccatcact gtgctggcca atacaggggg
    16861 cggcccccgc ggcttcgatg tctttgtcgt ggacaagatg gcgctggcgc cgaccgagtt
    16921 cacctgcctc ccgggggtgc gcacccacgg catccgcgga gccgacatca gcggtatcgc
    16981 cttcatgggg gctttcgtgc ccgcctccgc acgactgggt gccccgggta ccggtctcga
    17041 gactgtcctc aagggactcc agctgaccag gacactgtgt gcggcgctgt ccttgggcgc
    17101 gggtgagcac tcactgcggc tcgcactgga gtttgccgag gggcgccagc tgtacggacg
    17161 cggcctgctc gaactgccct acgccgtccg aacgctggct gatgccggcg ccgaccacct
    17221 gctgaacgag gcggtcgcgc tggtcggcag ccgctgcatc cacggacaga ccggcgaaat
    17281 gagcctcgtg tccgccattg ccaagtacct gctgccgacc cgcactgaca ggatgatctc
    17341 caccctgggc aggttcctcg gggcacgatc acagctgacc aacgtcgaca tcgacggccg
    17401 gttccagaag ctggcgcgcg accaccgcat tgtcggcatc ttcgacggga acacgctggt
    17461 gaacctgaac tcgatcatca acgagttacc agtcgtcgcc cgtcacgcgg ccacgccgta
    17521 cgacacggcc gctctccgga ccacgttgga cccggacgag ccgctgcccg aattcgacgc
    17581 caaccacctg cgactggtat cccgcgcggg cagcagcctg ctacgcgcgt ttccggatct
    17641 cgtccggcag atggagcaca cgcctacggg ggagcacgcg gcgcggattc tcgaacacta
    17701 ccaagatttg ctgtccgagc tggccgacca ccgtccagtg cggatcaccg tgccgaggcg
    17761 gagcttcgtc ctggccgagc gactgtccct gtgctgggcg gcggctgcag tgcttggaat
    17821 ctcggcgcac accagtcagt ccgatccgtt gtgggcgaat ggcctgtggc agcgggccgt
    17881 cctcggccgg attctcgagg ccctcggcga cgcagtcgcg cgccaggccg gccaggacga
    17941 agccctcgtc gacgccctgc aggcccgcct gcagcagggc ctgtcgctgt cgttgctgcc
    18001 gcaccgagtc gccgagggga cgagccgatg agcactgtgg gactggacag cttggagaat
    18061 ctgttcggcg atccgtttga cgatgagaat cccgtgggtt tcgcgggcgt tctagccgct
    18121 gacgaacagg ccgtaccgct cgccgacggc gagctgctgc tggacaagtg gaacttcaac
    18181 cacgagttcg tcccccgctc cctcggtggc cggttgaccg gggtagacga actggcccgc
    18241 aggctgcgcc cggtgttccg acgggatccg gccctgggtt tgggctacgg ggtcacctcg
    18301 ctgatggcgg cagtcaacgt gtgggcggct ggttccacca accagcgccg cagggtcgcc
    18361 gacgacctgc tggcgggcaa gcggatcgcc gtggccttcc acgagctggc ccatggaaac
    18421 gacttcctgc gcaacgaatt cgcagcgcgg ctcaccgcag accagatcgt tctgtctggc
    18481 accaagcagg tcatcaacaa catcgaacgc gcggaatctc ttgtcctgtt agcccgcagt
    18541 gccgacgcac cggggccgcg cgcgcactcg acgctgctga tcgacaagcg ggatctcccc
    18601 gaggactctg tccggtacat gccccggttt accacctcag ggatgcgcgg gtgtcatctt
    18661 ggcggggtcg tcttcgacaa cgtcccggtc ggtctcgacg cacttgtcgg cacccctggc
    18721 caaggggtgg agacggcgtt gcgcgctttc caggtcacgc gggcgacgct gccggggatg
    18781 gcgatcggca ccctggactc ggccctgcac ctcgctcatg atttcgccgc aagccgcagg
    18841 ctgtacgggc acaccgtcgc cgacctcccg catgcgcgcg gcaccctcgc cgcggccttc
    18901 acagacctgc tgatcgcgga ctgcctggca acggcagtca gccgcggcct gcacctggcc
    18961 ccaagagcga gctcggcgcc tgcagctgcg gtgaagtacc tggtgccgct gctgcttgag
    19021 gaagctcatc acgagttgtc ggtcatcctt ggtgcccggt cctaccttcg ggaggggcgg
    19081 cacgcggcgt tcggcaagtt ctccagggac cttcccctgg tcagcatcgg gcacgccggc
    19141 gcgacctcct gcctgctcac cgtcctggcc cagctcccca cgctcgccaa gcgcagttgg
    19201 tcaccggccg cgccgcccgc caaactgttc gacactgcca tcgcactccc cgaactggat
    19261 atcagcgggc tgtccgttag cgacaaggcg cccgatccgc tgatgtccac gctggcccag
    19321 gtacgcccgg atgacggcct gcccggactc ttcgccaccg ccctggccga gctgcacgcg
    19381 gacagcctgc gacttcccgc tggggagctg ggcccggcgg ccagtgccga agccttcgag
    19441 ctcgcgaagc gctacaccct gctactcgcg gcggcggcgt gcctgggcac caagcagttc
    19501 gccacatccg agttcctgag cagcccacag tggctgactg cagcgctcac ccggctcgcc
    19561 gcgcgactgg gccatggcga cggcgtactc gacgacgagc tcgccgagcc cttgttcggc
    19621 gagctcacca cccgtgtcga tcagcggctg tcctgcggaa cggaccgctc ctccatcttc
    19681 ggctgaaccc ccgctcccga gtcaccacac agaacatcag gagatgacat gacgttgaac
    19741 accgagatca gcccggtcga gcttgagttc tggctgatag aacgtgtcgc gagctacctg
    19801 cgcctggaca cgcgggaggt ggatccgcag gaatcgttcg ccaatctcgg cttggactcg
    19861 gtctacgcgc tgacgctgac cgccgatatc gaggacacgc tgggtatcga ggtcgagccg
    19921 accctggcct gggactaccc gaccatcagc gccctggcaa aggggttgac ggcgtcgatg
    19981 cgtgccgcca aggaaacggt atgacggaga tcgccatcgt cggtattgac gggcggtttc
    20041 cgggcgcggc gaatccggcg gagttctggg acctgctgat gcgcggtgcg gacgccatca
    20101 gcaccgtccc cgacgacaga tgggaccctg acgccttact gggctcgggc cggctgaaca
    20161 ccaccaccgg cggattcctc accgacccgg atgtcttcga ccacgagttc ttcggcattt
    20221 cccccaagga ggccgaggcg atggatcccc aacagcgcct gatggttcag gtcgcgtgga
    20281 gggcgctgga ggacgcttgc ctggatccgc gcgcgcaggc aggaaccgcc acggcggtct
    20341 tcatcggggt gatgggcaac gagtgggccc atctgcacat gaccgactac gaccggatca
    20401 ccccacacct tggctctggc aacggctact gcatgatcgc caacaggctt tcctacctgt
    20461 tggacctgaa gggaccgagc tgggcggtgg acagcgcatg ctcctcgtcg ctggtagctg
    20521 tccaccaggc atgctcggcg cttcggttgg gtgagtgcga ccaggcgatc gtcggcggag
    20581 tcaacatcat gatgactcca gcgctgaaca tcttctacac ccaggccgga ttgtcggccc
    20641 cggacagcgc ctgcaaacca ttcagcgccg aagccaatgg gatcgtgcgc ggtgaggccg
    20701 ttgccgctgt cgtgctccgc aggctggccg acgccgaggc agcaggcctg ccgatctacg
    20761 gggtgatcac gggcagcgcg gtcaaccagg acggccggag caacggcctc acagcaccga
    20821 accgctggtc ccaggagcag gtgatccggg atgcctaccg caaggcgggc gtcggcccgg
    20881 agcagatcgc agccgtcgag gcacatggga ccggcaccgt gctgggcgac atgatcgagg
    20941 ccaacgcact cggcgcagtg cacggcgtcg accgccccac cccctgcggg ctcggctcgc
    21001 tcaagggcaa catcgggcac accgagggcg cggccggcat ctcggcactg atcaagatgg
    21061 ccctcgccgc gcaccacggc gtggtgccat cgagcaggca cgccgacacc gaaaaccccc
    21121 aacttgccct gcgcgccaag ggcttgagac tgcttaaggc tcctcagcgg ctcaagggta
    21181 cggcgccttt gctcgcggtg agcagcttcg ggctgggcgg caccaatgcc cacctcgtgc
    21241 tgcgcggaca ccgcacgacg cccctgcccg agcggcccgc accaggcatc gtgacactgt
    21301 ccgccaacag cagcgcggga ctccagcgca acgcaacgca gctggcgacc gatctcgcca
    21361 agctgcccga gcgcagcttc gccagactgt gttggacgag caaccaggtg aagtcgacgg
    21421 gcaagcaccg actggccttc gccgcatcgg gttcccagga cgccgccgcg gcactacgca
    21481 ggttcaccga ggaccccgcc ttcgccgacg gtatatccga tgtggcgcag cgcgacgtcc
    21541 gggtcggctg gctgttcacc gggcagggct ccccatatcc gggcatgacg cgagcgctgc
    21601 acgaccggtt cgcggggtac cgccaggcac tggccgacgt ggaccaggct atggccgagc
    21661 acctcggccg atccgtctcc agtgtgatac tgggcgagga gccgctgatc cagcagaccg
    21721 gactggccca gccagcaatc ttcgcggtcg gctacgcgat gtcggtgatg ctgagtgagc
    21781 tgggggtcca gccggattgg ctgatcggcc acagcgtcgg tgagttcgcc gctgccgtcc
    21841 acgccggcgt attggccttg cccgatgcct gcgagctggt gacggcgcgc gctcggctga
    21901 tgcaggagct gccgtccggc ggcggcatgc ttgcggtgcg cggcgaaccg gccgaagtgc
    21961 tggacctgct tgacggcacg gtgggtatcg cggcgctgaa cggaccggaa gacactgtgt
    22021 gctctgggcc ggtcgacgaa ctggaacgca tcgccaaaac actgcaggaa agaggtatca
    22081 ccacccggac actggacgta tcgcacgcct tccactcgcc gctcatggag ccgatgctgg
    22141 cagagttcgc cgccgtagca gtcaagttca cctaccggcc tgccaccatc cccgtctact
    22201 ccacgctgta cgggcgggaa ctcaccgccg gtgaactgat ggacgctggg tactggaccg
    22261 agcacgcacg caatccggtg cgctgggccg acgccatggc agccgcccag gaccggcgga
    22321 ccgacttcat catggagctc ggccctcggc gggtactcgg tcctatggcc cgcagagctc
    22381 gccagacaac ggcggagatt ctcacccctt gccccggtcc ggcggccacc ggcctggaac
    22441 ctgcagacgt gatcgcccgg ctggccaggg caggcagcag gccgacgtgg gacgcgctgt
    22501 acgacgctga ccagcagcgg ctcgtccggc tgacgcccta tcgcttcgcc gccgacagcc
    22561 gattctggac cacggccggg aacgacaggc cgcgagcggg tggcactacc acccgccccc
    22621 accacgccga gccgtccgcc ccaaagcagg ctgatatcga tgacgtgcac acggctgtgc
    22681 tcgcgatcct cggcgatatc agtggccaca ggccgacaga gatctcggtc gctgcccacc
    22741 tcggcgacga actcggcttc gactccatca tggtcgtcca gctcaaggct cagctggaac
    22801 gccagtttgg aatcgccatc gatgcagtgg aactgctggc ggagatcgag acttccggcg
    22861 acctgatcac gtacctccgg cggcagccgg cccaccgcag aacagtaacg aggtgacagc
    22921 catgtccaca ccgaccagct acatccgcgc ggtgggcacc gctctgcccg gcgcaccgat
    22981 tgacaactca gcccttgccc ggcggatcgg tgtcagcgcc gaatggatcg acatgttcat
    23041 cggcacccga acccgccatt tcgccatcga cctcgatacc ggcgagcaga ccagcaccct
    23101 cgccgaactg gccgagcgcg ccggggcgca ggccatgcag caggccggga tcacagcgtc
    23161 cgagatcgac ttcctggtgc tcgcgaccgc gacgccagac gagttgatgc cggcgacggt
    23221 gaatcaggtt gccgaccggc ttggtatcga ccaagtgcct acgtaccagc tgcagtccgg
    23281 ctgcgctgga gccgtccaag ccctggacct cggatgcctg ctgctgcagc gccccgaaca
    23341 cgaaatcggc ctggtgatcg gcggcgatgt ctgtgccaag catctgcggc tgaaccggga
    23401 gttcggcacc ctcccatccg ctgagctggt caactacgtg ctcttcggcg acggcgcagg
    23461 ggcggtcgcg gtcgcccgcg agcggcctac cgctggtatg gccattcgca cggtgctcaa
    23521 tcaggtgacc ggccgcggac agcggccggg ccagatgatc cgctggttcg gcgaggccga
    23581 ccgggagcgc ggcggacagg ccgtggacga ggattacaag gctattgagg aaagagtgcc
    23641 cacgatggcg aaggagatcc tttggcaact gctggatgac gcaggctggc aggccgagga
    23701 cctggcatac ctgcttccgc cgcagctctc cggccggatg accgagcgga tcgtgtccgg
    23761 gctcggcatg cccggggcga ccgaggtcag ctgtgtcgcc gataccggga acaacggcaa
    23821 cgccctgccg ttcctccagc tcgaccggct tgcaggcatg ctgagtccag gcgagcgggc
    23881 cctggcgatc tctgtcgagt cgagcaagtg gatcaaagcc ggattcgctg tcgagggggt
    23941 ttgatggtgc cgcccatgac taccgatgct gatcaagcat gggaccgcct tcgcctgctg
    24001 cgcgacaatg gacggttggc cattgcctat gctgaggcag gaacactggc tggctcgcta
    24061 cctgagcgca ggcaggccgc gctcgggcag ctgctgctcg gcttggaccc caatgtggtc
    24121 accgcctcgg accccatggt cactgcgctc aacgtcgtga tcaccggcaa cgggaccacg
    24181 gcgcccctgc aggcgccatt ggccgctgcc ttcgctcgga accagctgct gctccgcccg
    24241 cgaggccagg gacagtacgt caacgacctg ggcgacccag gcagtgacgt gtactccgaa
    24301 cagaccgatc tcaccgtgtg cctgctcgat cccgacttga tcgcttccga gctcgcggca
    24361 gtgtggacag cagccgactg tgaacgcgtg ctccgatcgg ccggcgaccg gatacgtgcc
    24421 ctggcggccg agcacgaccg ggcagggacg ggcaccctgg tgctcaccac tgtcccgttg
    24481 cccgcgtggc tggcgaagca gctggtcgac ttccagtccc gggcaaggct cagcctggca
    24541 tggcgggagt tcaacgccga tctgctccga ctggccgcag agctgtcccg gtgcatcgtg
    24601 ctggacctgg acgtgttgct gaccgcgccg gtgtccctcg acgaaccgcg catgcgggtc
    24661 tacacccagg tcggctactc cgaagagctg ctctgccgta ttgccgacga gatcgccgca
    24721 gtcgcccgtg cactctgcgg acggaccaag aaggtcctcg tgttggacct cgacggcaca
    24781 ctttgggggg gtgtactcgg cgatgacggc gtggccgggg tgcagatcgg cccaaccggt
    24841 cccggcgacg cgttccggcg attccagcgc acggtggccc aactcggctc gcaaggagtc
    24901 cttcttgccg tctgcagcaa gaacgacgaa catctcgtgc gcgcggcact agcagagcgg
    24961 gccgagatgg agctgcgtga ggaggacttc gtcgccatcg tcgccaactg ggagcccaag
    25021 gaccggggga ttgccgggct ggctgaggtg ctcaacctcg gcgtggacag catggtcttc
    25081 gttgacgaca gcgccttcga gtgcgggctt gttggcgagc atctaccgca ggtagcagtg
    25141 gtcgaggtcg atcgggagcc cacacggcac gtcgaacagc tgctggccgg tgactggttc
    25201 gccgctctac ggctgaccgg cgaagaccgc gctcgccgga actcctatca ggccgaggtc
    25261 cagcgcgact ccctccgatc gacgtcctcg tcactgcagg agtacctcaa cggtctgggc
    25321 acacgggttg agatctttag cccggacgag caggatcagt cgagaatcgc ccaactaacc
    25381 cagcgaacaa accagttcaa tatggccacg gtcaggatgg acctcgcaca ggtgcaggca
    25441 gcgctgtccg ggccaggcag cgacgtgtgg gccgtccgtt ccggcgaccg tttcggtgag
    25501 gcgggcatag tcggcgtggt gttccaccga atcgccgacg accagctgca catcgacaac
    25561 atgctgctga gctgccgcgt cttcggccgc ggcctggaga gcgcgatggt gcgcgaggtc
    25621 ctggcgcacg cggcggagct gagagtggac cgagtagtgg cgcggtaccg gccaacgccg
    25681 aagaacggcc ggttcgccca gttctatgaa gagcacgggt ttgtggtggc cgaaaccgac
    25741 ggcgacacca cggtatgggt acacgacctg gccgagttgc ccagccccct cacccatctg
    25801 gccgtgacca acctactgcg gagaccgaca ccatgactga ggcggaattc ctgacactac
    25861 tggacgagga cctggggctg cggctgtccg ttgaggactt gagccgagac gtggacacac
    25921 tgctgcactg ggactccatg cacctggtcc ggctgctgag cgtgcttgag aggcgaaccg
    25981 gcaagagcat tgccctcaat tcgctgctgg aagcccgcac actgaaccag gcccgaaagc
    26041 tcgtgatggc cgatgcctag ggtcgccaag cagcgcaggc acacgctgta cttcctgcga
    26101 catgcacgcc ggatggcccc ggtcttcctg gacaccgatg tcgacttcac cgaggtgatc
    26161 gcccatcgga agcgcgcttc agaggaaggc gcccgatact cgtatctcag ctatgtgctg
    26221 cggtcggcga cacgggtgct ggagaagcat cccgactgca atgccgcact cggcggtggc
    26281 gtgctgccaa agctcgcgca cttcagcgcc gtgcgtccga agatcgccat ggaccgcacg
    26341 ctgtcggggc agcgggtcgt gctgtcggcg gtgttgccgg acttgcgtgg agccggcctg
    26401 gacgagatac agcgggcaat cgcacggatc agggataccc cggttggcaa actgcccgag
    26461 ttgcgcggca ccgtcatgct tcaccgattg cccgcgctgt tcggctggcc cgcattccgc
    26521 gcgggaatgg ccgccctcgg gaagcgcccg cagctgatgg gaacgctggc cgtgtcatcg
    26581 ctgggacacc gtgccgtcaa cggctttcac gcgaccgggg gcaccgcgat caccctcggc
    26641 ctcggccagg tgaagccaac ccccgtcgct cgggaaaacg aggttgtcat cgccccagtg
    26701 atgcgtctca acctttgctt cgaccaccgg gtggtcgacg gagccgaggc agcggacgta
    26761 ctcgacgaga tcaagactga tctggagaac acatcatgac cgagcagatc actgcccagg
    26821 cctgtgtgat cggcggcggc ccggccgggc tggtgttcgc gctcgccctc gctgcccgag
    26881 gccgcgatgt catcgtcgtg gagaagagtg aggacttcga ccggtccttc cgaggcgagt
    26941 cgatcctgcc ggactccgtc tggctgctcg accagttgga actgcttcag ccgctccgtg
    27001 accagaaagt tctggaggca cacgggctgg agatcagcga gaacggccgg cccgtcctgc
    27061 gggtcgactt ccgccagttc gaccagccgc agccgtttcc catggagatc ccgcagccca
    27121 tgctgctgcg ggttatcgcc gacgcggcaa gcaagcaccc agggttccgc atcatccgac
    27181 cggcgaaagc ggtcgtcttg ctgcgggacg gtgggcgggt gaccggcgtc cgctgccgca
    27241 ccccgcaggg cgatttggag atcaccagcc ccatcaccat tggcgcggac ggtcggtaca
    27301 gcaagattcg tgacatggca ggaatcgagc accacaaaac gccactggaa cgcgatgtgc
    27361 tgtggttcaa gatgccttac ccgcaggcgt gggaacccaa cagataccgc attcgcatca
    27421 accaggaccg acacgccgtc ttcctgccca cccatcccga catggtgcgg gttgggttaa
    27481 atattcccaa gggcggtctg aaagacttgc ggaccgcggg aatcggcgct ctttacgcgc
    27541 ggatggacga gctcgccccc gaactgggtt cactcgtacg gaaaaacatc acaagctggt
    27601 cgggcacaat gatgctggac atcttcacca ctgtggttcc acagtggagc atcccgggac
    27661 tcgtgctcgc cggcgacgcc gcgcacacac tctcgccgat cctcggccac ggcgtgaacc
    27721 acgcaatcat ggacgcgctc gtcctggccc ggctggtgga ccaggcgctg acaggtccgg
    27781 acactgctac ggcactggat cgggccggca cccggttcca gctcgtgcgc gagggcaagg
    27841 ttcgacaggc ccgcgatctg cagctccgcc aggagaagat cttcaccctc tcgtcgccgc
    27901 tggccacgct gacgcgacgc tcgctgtacc ggatgatcaa cgcattgccc ccggtaaagc
    27961 agcgggtgct cggccgggcc tacttcacca ttccgcaagt ggccgatccg gtcgcgaagc
    28021 agttgcagga tgtgggggca tgagcacggt gtccggtgct gaacatcgcg gcgacgccga
    28081 cgacctcacc gagttgaaga aactggtact gctccacgct caggcgcagg gcattccgcc
    28141 agccgactgc gcgcagttgc tgtggagcat cacctccgac ggcgccggta gcgcgggttc
    28201 ctgggttgat gtctggtcct ccgccgcaaa acgccatctc accgcaggcg actacctgct
    28261 ggcctgcagg cactacaaca tggcccggtt tccgttcgtc gatggtcctg aaagggatgc
    28321 ggccctgcga gaatgtgtga acgccttcca gcgctgggcg acgacccgcc agatcacccg
    28381 cgaggaggtg gtggtcggcg gggaccggat gccgttctgg ctgagtacct caccgcgtgg
    28441 cagggccgct cccgcgctga tcgtggtcgg cgggatcgtc agcatcaagg agcagtgggg
    28501 agagctgcta ccgatggctc ggcgccttgg catgacggtg gcctgcgccg agctgccggg
    28561 cgtaggggag agcaatgtgc cgtacgacag gaacgcctgg cggatcttcc ccgccctgct
    28621 tgatcgcctg gccgagctgc gcggaatctc cgaagcgtac gtgctcgcta tgagtttcgg
    28681 cgggaacctc gccatccggg ctgcggcgcg cgacgagcgg ctgcgcggca tctgcacggt
    28741 cggcgcgccg atatcgaagt tcttcaccga tcggcagtgg tggtcgcagt tgccgggcac
    28801 gaccttgcgc acgctcgctc atctgacggg gcatcccgtc gatgagctgc aggagaggat
    28861 cgcggactgg gcactcaccg acgccgagct gtctcaggtg gacatacctg tgcgctatgt
    28921 ggccagtcgc cgggacgaga tcattccggc taccgatccg gcgcgggtgc gccggcacat
    28981 ccgtgacggc gaggtcctgg agcatgacga tgtgcacggt tcaccccagc acctgctgga
    29041 gacacgtttg tggctcgtca ggtccttgct gtcgatgcgc ggcgccacag tcgtacccgc
    29101 tgtacttggt ctggcactga acctgctcgg gctgcagaac cggatacggg gcgggctacg
    29161 gtgaccttct acctgggtgt cccggtcgat cctgcctccg agctgcgcat gtactgcttc
    29221 caccatgcag gaggtggccc ctccctcttc cggggctggc agcgagcgct cgccccggaa
    29281 gtacaggtcc tgccggtgct tctgcccggc cgcgaccggc gcatccggga gcctcggttc
    29341 accgacatcg accgtctggt caaggaactg gaccgggagc tgggtccatc ccttgagcag
    29401 ccatatgtcc tcttcgggca cagtatgggg gcgctcatcg cacatcggct cgccgcctat
    29461 cggtcgacgg ccggagggcg tctgccggag gcggtgattc tttccggttg ccgcccaccg
    29521 cacctgccct ccgggctgcc gcccgccgac cgggtcagcg aggcgaaact cgtcagctgg
    29581 ctcaacgagg tcggcgggct gccagatgaa ctgctccaaa ggccggaatg gctcgcactg
    29641 ctgcttccca tcctggtcga tgacctcacc ctgtgcgcga gcgcggccca gcagccgttc
    29701 acgcggcttc cctgtcccgt gcatgtcttc ggtggcgacg aggatccgct ggcagggagc
    29761 cacgagctat ctgcgtggcg cacacacgcc gacgcggagt tcacggtgac cacgtgcagc
    29821 ggcggccatt tctacctcaa ggactcacca gcccagctgc ttgcacatct gcggaaggcc
    29881 ctttgcagat atcggtctcc gctgcgaacc agttcatgac cgcttattag tccgtcaaat
    29941 caagtctgga gatcaccagt gaccacagcg gatatcaggc agaccgaagc gcgaagcttc
    30001 ccctttggtc gggagcacgt gaccaagctg ccatcgatct atggacaact gcgggcgtcc
    30061 gagccggttt ccgccatcct gctgccgagc ggagacactg gctacctggt cagtcgctac
    30121 gacgacgccc ggctcgtgct ctccgaccca cgattcagcc gggctgccac catcgcgccc
    30181 ggggcgcctc gcctcacccc ggtcgacttc ccggcgggga gcctgttcac cctggacccg
    30241 ccggagcaca cccggctgcg caagctcgtc gccggcgcat tcaccgaacg ccgcgtgcag
    30301 tcgctgctcc cgcggatcca gcagatcacc gacgaacttc tgaatgcctg tgacacagta
    30361 ggcgaggagg tcgagctcaa ccaggccctg gcgttcccgc tgcccatcat ggtcatctgc
    30421 gagctgctcg gcgttccgca cgaagagcgc gagcgcttcc gggtgtggtc ggacgcggtc
    30481 gtctccctga ccgcgcacac cgccgaccag gtcgtcgccc gccaacgcga gatggctggc
    30541 tatatggcca acctgatcga gcgtaagcga gttgagggtg gagacgacct gctcagtgcc
    30601 ttgatcaccg cgcacgatga acagggcgca cttggcacga acgagctgat cgtgatggcc
    30661 atgacattgc tcgtcgccgg gcacgaaacg actgtgagca tgatcggcac cagcgtgctg
    30721 acactgttgc ggcatccgga aacagtgcac cgcctgctgg aggacgaggg gtacgtcgcc
    30781 cccctggtgg aggaactgct gaggctcaac ccgatcggcg acggcggccc gctgcgtatc
    30841 gctctggagg acgtggagat ggcgggcgtg gtcatcccca agggtagtgc cgtgatggcc
    30901 gccatcgggt cagccaacat ggactcgagc cggttcgagc agccagaagc actcaccgcc
    30961 gagcgagagg tcaacccgca tcttgccttc ggtcatggca tccaccgatg cctcggcgcc
    31021 gccctcgcca gggctgaact gcgaatcgcg atccgctcac tgttcatgcg attccccaca
    31081 ttgcgactcg ccaagccgat tgacgaactg cggatgaaac ctggcctgct ggtcaactcg
    31141 ctggagtcac taccggtcac ctggtgattc aggcgtatgt gaccatcaac atgacaaccg
    31201 aggcgaaggg ctcaatgcaa tgcgcattgt tgaaacgaat gtgacgatct ccgcacctgc
    31261 atccctggtc tgggacactc tcgtcggttt cgacagctat gccgagtgga acccgttcat
    31321 ggtcaaagcg gcgggccgtg ctgaaccggg cgagcggctt gccatcaccc tccggcagag
    31381 cgacacccgc accatgtcgt ttaagccgaa ggtgctcgtc gccgagccgg gcaggcacct
    31441 gcggtggatc ggcaggcttc tggtaccggg gatcttcgac ggcatgcacg agttcatcct
    31501 gaccgagacc agcgagggaa ccctactcga ccacaaggag acgttcaccg gggtactgcc
    31561 ggctctgatg ggaagcaagt tggactcgac cgcactgggc ttcgaacagt tcaaccaggc
    31621 actcaagcgc cgcgcagaat tccggcattc cgcaaccagt tgacgcggag ggaccgccac
    31681 cgcgtggtgt cttgtggacg tcgccacgcc gccgcagcgc acaggcttcc caagcccata
    31741 ggccggaccg ccatggcgag atcctcctcc ataggcacct ggaggaggcg ggagttggta
    31801 cggccgttcg ccgccctcca actggggtgc ctctatgtct ttcgtcaagc gaggcggggg
    31861 gtcggggttc gtagaaggtg ccgtcgcgga gcatcgcgaa gagcacgctg atgcggtgcc
    31921 gggcgagccg gagaagagcc tgtgtgaggg tcttccctct ggcccggcac ttgtcgtagt
    31981 aggtgcggga ggccgggtcg tgcagggccg cgaacgcgga caggaacatc gcgcgcttga
    32041 gctggcggtt tccgcctctg gacgcgtgtt cgccgtggat cgagatcccg gacgacttgg
    32101 tggctggtgc caggccggcg taggaggcga ggtgggcggc gctgtggaag ctggtgccgt
    32161 cgccgacggt gaccagcagg acggcggcgg tcctgaccgc gacccccggc atcgaggtca
    32221 ggacctggtg aagagggtgg gcctccagca gttcgctgat ctgggcttcc agggcccagc
    32281 gctggtcgtg aacggcgccg agcgagcggg ccagcgacgg gacgacgatg tccagggtgc
    32341 cagtccccgg acgacgacag tctgctcgtc gagtgtgtcg aagacctcgt cgatcagccg
    32401 tttcgccatc cggggagcct tgggccggat tgcttcggcg ggcctgcggc ggcctgcttt
    32461 tctcagggcg gccggggatc cgtagcgttc cagcagccag atgacggccg ggtggtcgag
    32521 ccgagggccg aggacgcgtt ccagcgaggg gtggaactgg gtgagcaggc cgcgtatccg
    32581 attggtggtg cgggtggcct cggcggcgag gtcctggtcg aagccgacga gcacggtcag
    32641 ctcggcggtg atctcgtcgg agagttccag cgagcgcagg gtgtgcggca tggtgcgggc
    32701 tgcgtccgcg atgaccgcgg cgtccttcgc gtcggacttc gcctcgccgg ggtagagatc
    32761 ggcgatccgt cgcatcgcca gtcctggcag gtaggcgacc tggcagcccg cgtcgcgggc
    32821 gacggtcagg ggcagagcgc cgatcgaggc gggctggtcc acgatcagca gcacagtgcc
    32881 gaacttcgcg gtgagtttgt cgaagacagc ccgtagcttg ggttcgctgt tgggcagggg
    32941 cttgtcgaag accttcttgt cggccggggt gagcccgtgg ccgtggtgag cggtcttgcc
    33001 gacgtccaga gcgaagaaca cgtcgacgtc gctgatgtcg tacaacccat cctcccgaac
    33061 ggggttggtc ctgtgctggc caggacgttg gtgccgtact ctcgcatcca cgttatgcag
    33121 acctgccacc cgcgagacgc cgggcgttgc gctcggcggg gcggtggtcg gacctctcat
    33181 cagcgtctcc attggcaccc cttcgggccc ggtgacaccc cccaggtcat ctcggacagg
    33241 gggacaccgt cataccgggc ccggaggcca gcggccctct tgcaggacac agagaacata
    33301 acggggcggc tcagccgcct acgagcagtc tgcattcccg gggtcttcga acctgcgaca
    33361 cccgctttag aacccctaac gcaacatggg tcgccgtgtc ctccgggcgg gtatgtcggt
    33421 tgcttgggtg cgagcgagcg aaatcctcaa ccatgggtgg ttgacgacga gttgtggttg
    33481 aggatcgagc cgttactgcc gtcgtcgccg cgtgggcacc ggcaacccgg gcggaagagg
    33541 gtgctggagg accggcaggt gctgcacggc atcctgttcg tcctctacac cggcatccag
    33601 tgggaatggc tgccccagga gctcgggttc ggctcgggga tgacctgctg gcggcggctg
    33661 cgggactgga acgacgccgg ggtgtggcag cggctgcacg aggtgctcct ggacgagctg
    33721 cggccggccg cctggacctg tcgcgggcgt tgatcgacag ctcccatgtc cgggcgctca
    33781 agggcggccc aaaaccggac ggagcccggt cgaccggggc cggccgggct ccaagcacca
    33841 cgtgatctgc gacgccaccg gcatcccact ggccgtgacc ctgaccggcg gcaaccgcaa
    33901 cgatgtcacc cagctgatgc ccctgctggc agcgatcccg cccatccgcg gcaaacgcgg
    33961 ccggctccgc cggcggccga aggagatcta cgccgaccgc ggctacgacc acgactgcaa
    34021 ccgccgccag gtctgggcac gaggcatcaa gccggtcatc gcccgccgcg gcaccccgca
    34081 cggatccgga ctgggaacca agcgatgggt cgtggaacag acgatcggac tgctgcactg
    34141 gttcaaacgc ctgcgcatcc gctgggaagc ccgggacgac attcacgagg cgttcctcaa
    34201 gctcgcctgc tcgctgatct gccggcgacg cctgcgaacc acgttgcggt aggagttcta
    34261 agcccgcgcc ccgacgcgcc cagccgccac ggcgagggac tggcctcccg ccaccgccag
    34321 cacctgacgg ttttaccggt gcgtcccagt accgcgatcg agctctctgc ccgacggtaa
    34381 gatcaccgct cgtataccgg aaggcggggt cgccgcagcg cctgccgacc tgtgccgagg
    34441 gccgaggggg aggggcagga tgcccgaggg gaacggatag ctcagcccgt cattcgagcg
    34501 catccttctc ccgcctgcgg tcacagaggc cttcgccgac ctgacccttc ccgttgaacg
    34561 atcccggttt cttgccgact tcccgctctg gcacgtcacc gagacccgct gggacaccct
    34621 cgcccaaacg gccgatgtcc gctaccgcga gctgacgggg gaccatcccg ttgtgccgac
    34681 caaggctgcc atttcgttga gacacgacct cgaacccggc agcctctacc tgcgggactc
    34741 cacacatgag ctgcacctac tgcgcccgtt cctgacgggc gaggtctgcc cggtttgtcg
    34801 cgcatggtcg accttccacg ccgatctcgt ccccaagggc ggagtacagc tgaaaagcct
    34861 tgaacacggg catgtgctac accagcccgc aggcaagtca aaggcgttgg tcgacgtcgg
    34921 tctactctga cgtgcggccg tccacttaac tagcgcaacc gcctcacacg gcgcagaccc
    34981 cgacttcacg gggtctgcgc ccctctcgcc ctagggtggt cagatgatcc aggcccctta
    35041 ccgattctcc gtggcagacc tggaacggtg cacaatctcc gtcggtcatt ggtcgagcca
    35101 cccgaccaat gaccatgcag gccggggact tgggcctggc gatcaccaaa gtccgcacca
    35161 ggtcgttctt cccgagcttg ctggagtgca gacgccgcat cgatcgggcc ctctacccaa
    35221 tgctcatgga gaccgtgtcc actggcagtg tcgatggcct ggtcaaagga ctgggcggcg
    35281 atacaggaat atccaagtcc gcggtcgcga gggtctgcca ggatctcgac accgagctga
    35341 gcgtgtttcg cccccggccc ctagaccaca tcaccccctg tcgtgctcgc tcggcttgtc
    35401 ggatcccgtc tcagttgtgc gccccaagga gcggcggcct gggcgagccg gaggtgtgtc
    35461 aagacggtcc ctggacgctt gcagtacccg cctcaaccgc tgcggcaacc ctcaagaccc
    35521 gtcggcggag gtgctgactg gcctgtcgat gactcgggtt gcccgcttcc gggcacttcg
    35581 tcacggcaac gccgagctgt ttggctgcgc agggggctgc gctgtgccgt aatgattccg
    35641 tggatctgaa ctcgctgcgg aagctcgttg aaggccagct cctacggttc gagggcaacg
    35701 cctttcagga ctgcatggac cgattcggcc tggagatgta ccccggggat taccagccgg
    35761 tgagggcagc cggcccgaag ggcgatacca agaacgacgg ttactgcccg aaagcccgcg
    35821 tgttcttcgc ggcgcacgcg acacgagccg agcggatcga taggacgaag gcaaagatcc
    35881 gcagcgacct ggcgggctgc ctcaaggagc accgagatgt gaaggtgtgg cgtttcctca
    35941 ccaacgacac cctgcccggc gaggttgacc agttcgtcga caacgagctt cgccccctct
    36001 acgccagcgt caccatagag gtatggggac tcaggacact cgcgaatgag atttgcaggc
    36061 tcacccggtt gcaggtcgac cgggtcctcg acgtcaacac ggacacggag cgctggcccg
    36121 ctccgaacgg agactctggc cgtggagacc gtgccgtcta ttccggaaga ccggttgagg
    36181 aattaacgga cccccatgcg cttgaagtac ataaacctat tgtggtgcaa aatgccccga
    36241 tcggcctccc agtatacata gcacgcagcc atgacgtagt cctccggcag gaattggcct
    36301 ctccgggatc cgcgctcgtc gtcctcgtcg gcgggtcctc ttcagggaag acgcgcgccg
    36361 catacgaagc tgtcaggtcg atgagtggct ggatgcttca tcatccgatc ttccccagcc
    36421 ggagtagtgc cctgatagaa gtgctgcagt cagaatctgt cgctccgcag acaatcatct
    36481 ggctgaacga gctacaagac tatctgatga ccgacacggg agaggtggcg gcctctgcga
    36541 tacggaaggc gttgcttagt catagggacg tgaagttcgt ggccaccatc tggccgcggt
    36601 actggcaaga cattacagat ccgggtcgac cttttcctgg aggcagggaa cttctcgcta
    36661 accaggcaat acgcgtcgac attgacaccg agtttcgggg cgatctcctc gtatcagctg
    36721 cacaatccga tatgcgtttc aagatggcac tggcatcctc acctacgagg gtcacacagt
    36781 atctcgcggc cggccctgcc ctgcttgatt tcttcaagga ttgcaaggat cggaatcccg
    36841 gcgcctgggc cgtgctatgc gctgcgatgg acgggcacat agcggggcat cctcaatttg
    36901 cgacttcagg attcctagct gatgccgcac ccggatacct gaccgatgag gaatggggag
    36961 cagtcggcga cgactggttc gaaggagcgc ttgcctgtgt aacggccgaa cttcgcggcg
    37021 cgatccggcc tcttgcgagg atccgtccta ggggtggccg gagctccgga gtctactatc
    37081 gtcttgccga ctacttggtt caatattccc aacaggaacg gcgcgagagt cccgtgccgc
    37141 gcagtttctg ggatgccgtt ctgcagcacg ccggcgaccc ggtggctgca tccgtttttg
    37201 ctcgggccgc tggcgacaga ggaatgcaca aagaggcagc tgagctctgg atgccgctgg
    37261 ccctggacgg cgactcgggt gcgctccatg agctgctgca aaatcccacg gtaactagtg
    37321 aagatatatt gccactggcg catgccgcca ttgatgctat ctcgctgtgt gacactatgg
    37381 ggctcggctg gatgctcatc gagttttatc atcacgaatc cctgaaagcg cgtctcgtgg
    37441 atcgaatcag tcgaagcccg catgatttga ggatcggtcc ccctattgat atggggcaga
    37501 tcctggagga acttgacgcg gcccatcatg gtgaagccgt tcgagtctac tcccaaacca
    37561 ttcgatccca gcttgcgtcg atagacgcgt cggatttctg gtcattttct gcgctctcag
    37621 gcgcccttct tcggtcggaa gtctgggagg ccaacgaagt aggaagggcc ctcgcgcgct
    37681 cctatttcct aggccgcaag atggaggtca cgaatctcgc ctattttctg gcgcatctga
    37741 ctggccacct agacagcgac gcggagttca tagacgaggt gcgggccgag ctaaattcgc
    37801 gcatagatga agtcgacgtc acagaagtca tctcgcttca tccagcgatt gttaacctct
    37861 tcaatgcggg cgaggatgaa ctcgggaaca ttctgatcgc gcgtgcctcc gaggccgtcg
    37921 acaccatgat cctgggaagc tcatatgcgc cactggaatt gatggaactg ctgtacgggc
    37981 gaggggacct tgatacgctt aagcatcttg cgttgcgaat cgccaaagat tttgatccga
    38041 tgctgtcgca tgcagccctg acctctctta ttcgcctgcg taaggtggaa tgtcatgagg
    38101 cgttcgccat catggccaag cgcatggcga cgaccgggcc ggttcttccg gtagcgggcg
    38161 cggaagactt ggtgaccttc tatgaacgga caggtctagc ggaacttcgc gatgcctatg
    38221 cgacgcgcct tctcaatttt cgacgccacg agggggcggg aactgtttag ggggtgttgt
    38281 ctagcgatct tgagtgcatc ctccagtacg gttcacctcc gcccgagcgg agggggcctg
    38341 ccgcacgatg gggtgacatc tgaactagct tgctctgtga ggaagttggg aagaatacca
    38401 ctgtgcccaa gccttatgcc ggaagagtcc cgccagggtg tcgtccgtgt cgcgcggaac
    38461 cgcggcccgg cgtgacggtc gagcagctgg ccgccgactt cggagtccac gccatgacgc
    38521 tgtggaagtg gatgcgccgc gcggacatcg acgacggggc aaagcccgga acatccagtc
    38581 aggagagcgt ggaaccaagg gagacgcgtc ggtggatcaa gcggccctga acaatgctgt
    38641 tgcccgccgc gacaacgtcg ccgggtgaat tgtccacagc gatcgcgggt cgcagtttcg
    38701 gtcagggaag ttcgtccggg ccctcgccgg ccaccagata gccggttcga tagggagagt
    38761 cggggcggca ggcgacaacg aagtcatgga gtcgtagaag aacgtcctcg atcgccgaga
    38821 gtgggccacc cgtgaggaac tacgaatcgc gatcgtgacc tgggccgaga ggaagtatca
    38881 ccgacgccgc agacaagcct tgttcggtcg gatgacccct gtcgagttcg agattgttat
    38941 gactacaccg gccctccggg ctacgtgacc acacctgtca cccaaccctg cagcagaccc
    39001 gtggtcgata tggcaggggt gggcaaggtc tcgttctgca gggcgataca tagcaggtga
    39061 tccccggtta ccgaaaccgg ggatcgtccc gatgattgag ggtgttcaca ctcggctgtg
    39121 cttgccagcg gagccggggt gaatgaagca gacaacgctg caaaccccgg acgaggagag
    39181 tgctgttgtc tgctgccctg atgaccgtgg tgcccttcgc tgaaagacag cgtcggcact
    39241 gccgatgtgg agtttccacg ccctcaagga gagtgaacat cctgtctcaa ccgatcaaga
    39301 agctgccgcc gaacgcgaag ggccaggtcc ggtaccggtt tgtggttgac gtcgggaccg
    39361 acccggccac cgggaagcgc aagcagctga cccgtaccct cggcacgctc agggaggcga
    39421 aggccgagta cgcacgtatc acggtccgtc gccacgaagg ggcgctcgtg ccacgcaaca
    39481 agatgaccgt gaacgagtgg ctcgaccagt ggctcgccaa gaaggcggaa gacctggaag
    39541 agaccacgat ctccacctac agggtgaccc tggaccgtgt ccgaggcagg cttgggcata
    39601 tccggctcca agagctcacc gaggacgatg ccgaggcgtg gatgctgtgg gcgctgcggg
    39661 agggccgcgt acgtgccacg aaggccggtc ccggtcttgg ggttacctcg gtagagatgt
    39721 ccctcacgag gctgaaggaa gccctcaacc gggccgtggc gcggcgcctg gtcgcggtga
    39781 atgtggccca ggaggtcagg atcccccgaa aggtgtgcaa ggcggagcgg caggcgaagg
    39841 ccgaggtgcc gccctggagt gtcgcggagg tccatgcctt cgtacgcgcg gtgagggatc
    39901 accggctgta cgccccgctc tgcctgtcgt tgatgggtct gcgcccggcg gaggtctgcg
    39961 gcatgcgttg ggccgatctg gatttggagc cagccaccct ggccgttgcc aacacgcgca
    40021 cgttgatggg gaacaagacc gtggtcgaga aggatacgaa gtcgcttacc ggggaacggg
    40081 acctcccgct gcccgttctg gtcaaagagg ccctccggag cttcaagggt acccaggctg
    40141 ctgagaagcg ggcggcgggg caggcgtacg aggacagcgg gtacgtgctg ctggacgaac
    40201 tcgggacgcc gctcaatgtg cggcagttgc gtgagcaggc gtacaaggtc atggccgaga
    40261 acgcgctgcg gcgggtccgt ttgtacgatg cctgcgccag ttgcttcacc tacctggcga
    40321 acaatggggt ccctgatcat ctcctcgccc gttgggcggg gcacaccgat gtgaggacca
    40381 cgaagcgctg gtacgtgaag ccggacgtgg aagatcttcg tgcggcggcg aatgcctgga
    40441 gtggtctcac cggtctcccg acccctgtgg tgagagaggt gtgagacgtg ggagcctggg
    40501 acgggtgagc gagacgacga agaccctgca gcaccgcttt gacgggcccg aagacgcacc
    40561 agtcctggtt ctgggcccct ctctgggcac cacctggcac atgtgggacc gccagatacc
    40621 cgagctgacc cggcactggc gggtgctccg cttcgacctg cccggccacg gtggcgcccc
    40681 cgccgcgccc gccgccaccg tcgacgacct cggcgaccgg ctcgtcgcca cgctcgactc
    40741 gctcggcgtc gaccgcttcg gctacgccgg ctgctccctc agcgccgccg tcggcatcga
    40801 cctggccctg cgccacccgc accggctcgc ctccctcgcc ctcgtcgccg cctccgcccg
    40861 ctacggcacc gccgactcct ggcggcagcg cggcgccggg gtccgcaggg acggcctcga
    40921 ccccgtcgcc cgctccgcgc ccgagcgctg gttcaccgcg aacttctccg gcgcccagcc
    40981 cgccatcgtc gactgggccg tacagatggt cggcaccacc gacacgtact cctacatcgc
    41041 cgcgtgcgac gcgctggccg ccttcgacgt acgggccgag ctgacccgca tcagcgtgcc
    41101 gacgctggtc atcgtcggcg ccgaggacac cacgacgccg cccgccgacg cgcgcgtgct
    41161 ggtcgcgggc atccacgacg cgaaactggc cgtggtgccc ggtgcgtcgc acctggcccc
    41221 cgtggaacag ccgtcggcgg tgacggacct gctggtccgc catttcacga cggcctggca
    41281 gatgtcgacg cagcaggggc tgtcggcggt gacgggggcg tctccgacgc agggcacggc
    41341 gggtgcggcg gggacgacag gggcgggagg tccggccgcc ggtgcacccg gcgcgggctt
    41401 cggtgccccg gggtccggcg cgggcggggc tttcggcacg ggcgcgccgt ccggcggccc
    41461 gggaaccggt accgcttcgg ccatgccccc gggcacgggt caggacggca cgaacccggc
    41521 cttcggcgca ccgggctccg gtacgggcgg cgccttcggc ggcccgggtg cgggcgcggg
    41581 cttcggcgcg ccgggggccg ccgacaccgg cgcgactccg cccggtgcgg gcgcgggctt
    41641 cggcgcgccg ggggcgggtt ccgccgctcc ggctcccggc atgcccgccc ctgcgggtcc
    41701 cggcgcttcc gggccgggtg gaccgggggc ttccggtacc gggttcggct cggtggggcg
    41761 ggggcctggt gcccaggacg ccgcgggtcc tggagcttcc ggatctggtg cgggtacctc
    41821 gggatctacg ggtacgggta cgggcgcggg tgccgggccg gtggggcagg gggccggtgc
    41881 gtatgagccc gtaggcagcg gcgcttccgg tccgggcgcg cccggaggga tacccgggcc
    41941 ggcgccggcc ggtggcgggt tcggggccgt gggtctgccc gctcccgggg cggggctgcc
    42001 cggcatggcc ttcggcgcgc ccggcggcgg ctcggccgcc cccggcgccg gcgccccgcg
    42061 cgggttcggg ccgcccccgg cggacatgca cggccccgcc gacgaccgcg agcgcggcga
    42121 gcgcatccgc cgcgaggtcc tcggcgacga gcccgtcgac cgggacggct tcaccggcga
    42181 cttccacgac ctcgtcaccc gctccgcctg gggcggcgcc tggtcccggc ccggtctcga
    42241 ccgccgtacc cgggccctga tcaccctgac cgccctcacg gcccgcggcc acgtcgacga
    42301 gatcgccccg tacacccgcg gagcgctccg cagcggcgtc acccccgacg agatcaagga
    42361 gacgctgctg cacacggccg tctactgcgg cctgccggcc gcgggcgccg cgttcgccgc
    42421 cgcgcagcgt gtcatcgccg aggaggcggg ctccggggcg tagcagcagg ggcgtagcag
    42481 tatgggccca tggagctgaa gctgacgaag aagagccacg cgtgcgtccg cctggagaag
    42541 gacggccgca cgctcgccat cgaccccggg gccttcagcg aggcggacgc ggccgtcggc
    42601 gccgacgcga tcctcgtgac ccacgagcac cccgaccact tcgccgagga ccggctgcgg
    42661 gccgcgctgg aggcgaaccc cgcggccgag ctgtggacgc tgcgcagcgt cgcggagcag
    42721 atcgccccgg ccttcccggg gcgggtgcac acggtggggg agggggacgc cttcacggcg
    42781 gcgggtttcg acgtgcaggt gcacgggcag ctgcacgccg tgatccaccc ggacatcccg
    42841 cggatcacga acgtcggcta tctcgtggac ggttcggtct tccacccggg cgacgcgctg
    42901 acgctgccgg acgtgc
//
