LOCUS       NZ_LNBE01000002        21074 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces roseifaciens strain MBT76 scaffold_2, whole genome
            shotgun sequence.
ACCESSION   NZ_LNBE01000002
VERSION     NZ_LNBE01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseifaciens
  ORGANISM  Streptomyces roseifaciens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1142035)
  AUTHORS   Wu,C., Zhu,H., van Wezel,G.P. and Choi,Y.H.
  TITLE     Metabolomics-guided analysis of isocoumarin production by
            Streptomyces species MBT76 and biotransformation of flavonoids and
            phenylpropanoids
  JOURNAL   Metabolomics 12, 90 (2016)
   PUBMED   27073352
REFERENCE   2  (bases 1 to 1142035)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     The complementarity of genome-mining and NMR metabolic-profiling
            facilitates lead-finding
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 1142035)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2015) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.06
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001445655.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 03:28:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,528
            CDSs (total)                      :: 7,450
            Genes (coding)                    :: 7,245
            CDSs (with protein)               :: 7,245
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 205
            CDSs (without protein)            :: 205
            Pseudo Genes (ambiguous residues) :: 0 of 205
            Pseudo Genes (frameshifted)       :: 77 of 205
            Pseudo Genes (incomplete)         :: 168 of 205
            Pseudo Genes (internal stop)      :: 20 of 205
            Pseudo Genes (multiple problems)  :: 56 of 205
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:37:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 219377
            Orig. end                         :: 240451
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LNBE01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21074
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /product="RiPP-like"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..21074
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="neighbouring"
                     /product="terpene-precursor"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..21074
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11074](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11074)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(589..604)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.61"
                     /tool="antismash"
     misc_feature    590..603
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.35"
                     /tool="antismash"
     misc_feature    636..645
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.63"
                     /tool="antismash"
     gene            complement(885..1628)
                     /locus_tag="AS857_RS02840"
     CDS             complement(885..1628)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128614.1"
                     /locus_tag="AS857_RS02840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_079110108.1"
                     /transl_table=11
                     /translation="MNAPQPPHGPEPSHSPGAQAQRSPEARPIRVLLVDDDPLVRAGLS
                     FMLGGLPDIRIVGEAADGSEVTALVDRHAPDVVLMDIRMPSVDGLAATEELRRREGAPE
                     VVVLTTFHADEQVLRALRAGAAGFVLKDTPPAEIVAAVRRVAAGEPVLSPAVTQQLITR
                     VTERERDTRGDRARALLAALNDREREVAGCVGRGQSNAEIAGALYMSVATVKTHVSRIL
                     TKLGLNNRVQIALLVHDAGGPGAEA"
     gene            complement(1625..2809)
                     /locus_tag="AS857_RS02845"
     CDS             complement(1625..2809)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072632.1"
                     /locus_tag="AS857_RS02845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine kinase"
                     /protein_id="WP_058041501.1"
                     /transl_table=11
                     /translation="MDVKTEETAEVQPRTARSVRDWAVDILCIALAAVIGILAAEALRK
                     DPGASPALLFFDQIVGALACVALWMRRRWPVPLAVVLVVVSTPVPPAAGAMLVAVFTVA
                     VHRPFRTVAAVGGLALISEPLQAAIRPDPDLPFPAATATGLLLVLTVIGWGMFVRSRRQ
                     LVLSLRERARRAEAEAQLRAEQAQRLARERIAREMHDVLAHRLSLLCVHAGALEFRPDA
                     PPAEVARAAGVIRDSAHQALEDLREVIGVLRAPGAEGGGDRPQPTLAALEELVEESRQA
                     GTEVVLDQRVADAPSVPEATGRTVYRIVQEALTNARKHAGGAAVRITVEGSPEAGLTVG
                     ITNPPGDGSGASVPGSGQGLIGLAERAALAGGRLSHGPTPDGGFRVDGWLPWRP"
     gene            2989..3207
                     /locus_tag="AS857_RS02850"
     CDS             2989..3207
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016469751.1"
                     /locus_tag="AS857_RS02850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_058041502.1"
                     /transl_table=11
                     /translation="MKKLLEGVGVILVLQGLGGVVHGLTGWFHYWVVVRYLGFLDGYEM
                     YASIVLAVIGTALVIASDSVEAESARE"
     gene            3212..3688
                     /locus_tag="AS857_RS02855"
     CDS             3212..3688
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004954998.1"
                     /locus_tag="AS857_RS02855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cupin domain-containing protein"
                     /protein_id="WP_058041503.1"
                     /transl_table=11
                     /translation="MADRTSGTSELVELLGLQPHVEGGWFRETWRTSREAVPDGYGGPR
                     AFATGIYYLLHPGEVSRWHRVRSDELWLWHRGGPLLMRLGGSGDTPDGKDAAEVVVGPG
                     VERGEQPQFLVPGGVWQSAGPAGDEPVLVTCVVAPGFDYEDFEDSEDPEDSARG"
     misc_feature    3767..3783
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.64"
                     /tool="antismash"
     gene            3813..4964
                     /locus_tag="AS857_RS02860"
     CDS             3813..4964
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013006252.1"
                     /locus_tag="AS857_RS02860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_058041504.1"
                     /transl_table=11
                     /translation="MGRFKRTLIAAALAATVVAGTAGWAVSDEQAVVSGPPAGAEAWRA
                     DHSLHRELPDPATAAPRTVAAFFAGLTEAQRKDLAARHALVVGNLDGAPVPLRYEANAR
                     AIAAEREKMQARAADPGLTRAAREEARERADRCERLLAPGRRILAFDPRGRGQVAEVYG
                     DLAAARHTAVIVPGSDIDLRTFDRTKDRYGTPTGMAASLRAEMERRAPGTPTAVIAWAG
                     YTTPVGLGLDAATGRLAQAGAVRLERLLAGLAAAAASPAAPPPSVFCHSYGSVVCGLAA
                     PSVDRTEAADLVALGSPGMRADSVAGLHTGARVWAAARNSSDWIGNVPNVDLFGLGHGT
                     DPTSAEFGARVVPTHGAHGHTGYFAPGTDSLRNFADIALGAYA"
     misc_feature    4995..5008
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.12"
                     /tool="antismash"
     misc_feature    complement(4996..5009)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.02"
                     /tool="antismash"
     misc_feature    complement(4997..5010)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.12"
                     /tool="antismash"
     gene            5035..5652
                     /locus_tag="AS857_RS02865"
     CDS             5035..5652
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006143827.1"
                     /locus_tag="AS857_RS02865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_058041505.1"
                     /transl_table=11
                     /translation="MTHVVLDAKGLRALAHPVRVQLVGLLRLYGPSTATRLAERLGLAS
                     GATSYHLRQLAAAGFVAEDASLGNARERWWRAVHEATVIDDDELAEQEPEAMLGYVQGV
                     VAAHTLRTQLAVAAYPALPKPWRDAFDMSDWNLRLTPQEAAELTGELRAVVERYRQYAS
                     GADAPADSEPVALTLHLLPDPAVAEGRTEGGAGAGADRREGA"
     gene            5649..7028
                     /locus_tag="AS857_RS02870"
     CDS             5649..7028
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017946594.1"
                     /locus_tag="AS857_RS02870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_079110013.1"
                     /transl_table=11
                     /translation="MTPPAPRRGRISGRLPYPRRPGGALGGPSAGRSVRPLAGVLAATA
                     VSLTGTRVSAVALPWFVLVTTGSAAQTGLVAFCEMTPYVVVKMLTGPLVDRVGPRVVSW
                     ATDSLSAAAAALIPLLHALDLLPFWLLLGLVAVIGAVRGPGDLAKAIMVPEAAERSRVS
                     LERATGLSGVTERLASTVGPAAGGVLVALLGPMAGLVVNAVCFALGSLVIALALPRGMG
                     LAVPSGDAPTDGGTGEPAGYWRRFGEGFAFLRGEPLLLTIIVTAGITNLLDVGFTAVLV
                     PVWAESSGGGPAAIGLTSSAAGVAAVCGSLVAAALAPRLRRRPVFFAGFLLAGAPRFVV
                     LACGAPLWVVLVVFAVSGFGGGFLNPILGAVSFERVPRALLGRVRALGDSLAWAGIPLG
                     GLLAGLAVTSAGLTPVLLVGGAMYFLTTNLAGLRPEWREMDRRRGAGTPREAPEGVAVR
                     S"
     misc_feature    complement(7061..7078)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.76"
                     /tool="antismash"
     misc_feature    7078..7092
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.48"
                     /tool="antismash"
     gene            7086..8234
                     /locus_tag="AS857_RS02875"
     CDS             7086..8234
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003974614.1"
                     /locus_tag="AS857_RS02875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_063804170.1"
                     /transl_table=11
                     /translation="MLWKSRKTSRRSFVAAALLMAFAAPQMPAVAAAAERTPGPAAPGT
                     PAEVPAPTGKMPVGTKTLHLVDTSRPDPWKPAAGKRQLMVSLWYPARHQGDKNAPYVSK
                     ELSKAVLGKEDLAGVRTNSTLDAEPAGKPRPLVVLSPGFGMSRLTLTALGEDLASRGYA
                     VAAVDHTYEAPVEFPGGRIETCETCAKPDMAAVVRNRAKDFSFLLDRLTAPGSPLAVDR
                     GRIAVVGHSIGGASAVEALRGDKRVDAAVNLDGNFPIDLPAEGLKKPVMLFGAQRSGDD
                     AENWNKNWQRLTGWKRWLDVPEGGHLTFTDAPWIADRFGMPDQIPPEQVHGAYGSLHGI
                     RSTALTRAYVNAFVDRHLRGTPSPLLDRPSAAYPEVTVLKKK"
     cand_cluster    8246..>19473
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    8246..>19473
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[13245:>14473](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      13246..>14473
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="2"
     gene            8356..9957
                     /locus_tag="AS857_RS02880"
     CDS             8356..9957
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (115-496). E-value:
                     3.5e-19. Score: 61.3. Matches aSDomain:
                     nrpspksdomains_AS857_RS02880_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004953346.1"
                     /locus_tag="AS857_RS02880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_079110014.1"
                     /sec_met_domain="PF00561 (E-value: 5.6e-25, bitscore: 84.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFELRKSRRTVPAVFALSAVSAALAAVVAAAVLPAGAAAAQQGAT
                     AQPRPATAVTVPERYASQKLAWQPCPELATMECAEMTVPRDWHAPDAGKDLTIAVSRVR
                     ASDPAHRRGVLMMAAGGPGGKGLLRPAGVARKAPAIGAVHDIVSFDQRGVGRSTPLQCQ
                     TQDELDAFFAGDFRDRSPAAVQRVVDNSRKLADACRAKHGDLLPYITTEQTVRDMDLFR
                     ALLGERKISYYGASYATMVGAYYASLFPQRVERAVLDSNIAFGGTWEDFEKGQPKSFQR
                     RFEQDFLPWLAKNDATYHYGRTAAEAKATWERRRSALRDHPLSPGEGKGRTLDPNRFDS
                     GTIQAIYDSQEGFPALAKALAALEHWDTAAPAERKLVDTVFGSYLGTNFFAEFLSVTCA
                     DTPWNRDTGSWIRRSAEDTAKYPLMGARELAFASACAAWPASPAPRVKVTGKGLPPVLM
                     LNSLHDPATYYEAAQRAHRDLRGSRLVTVTGGDHGVYLGGSACADGIVNKYLLSGELPA
                     RDVTCEDAPLPAPAAK"
     aSDomain        8701..9843
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS02880_Abhydrolase_1.1"
                     /evalue="3.50E-19"
                     /label="AS857_RS02880_Abhydrolase_1.1"
                     /locus_tag="AS857_RS02880"
                     /protein_end="496"
                     /protein_start="115"
                     /score="61.3"
                     /tool="antismash"
                     /translation="MMAAGGPGGKGLLRPAGVARKAPAIGAVHDIVSFDQRGVGRSTPL
                     QCQTQDELDAFFAGDFRDRSPAAVQRVVDNSRKLADACRAKHGDLLPYITTEQTVRDMD
                     LFRALLGERKISYYGASYATMVGAYYASLFPQRVERAVLDSNIAFGGTWEDFEKGQPKS
                     FQRRFEQDFLPWLAKNDATYHYGRTAAEAKATWERRRSALRDHPLSPGEGKGRTLDPNR
                     FDSGTIQAIYDSQEGFPALAKALAALEHWDTAAPAERKLVDTVFGSYLGTNFFAEFLSV
                     TCADTPWNRDTGSWIRRSAEDTAKYPLMGARELAFASACAAWPASPAPRVKVTGKGLPP
                     VLMLNSLHDPATYYEAAQRAHRDLRGSRLVTVTGGDHGVYL"
     gene            complement(10001..11074)
                     /locus_tag="AS857_RS02885"
     CDS             complement(10001..11074)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523224.1"
                     /locus_tag="AS857_RS02885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_058041507.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.6e-55, bitscore:
                     184.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTQAGPVPPQTALRTPAPQTLARARALAEPALRAAVATLHPLPA
                     RMAAFSFGWCEADGTPSPSPGGKGVRQAFALLGAEAVGAPLGTAVQAAVAVELVHTFSL
                     VHDDIMDGDERRRHRDATWKAFGTGPAVLTGDALFALAVRTVAEAGGEHTGRAVAHLAD
                     CLGELVRGQADDLLFESRPWTGRGAVGIPEYEAMAARKTGALLGCALSLGPVLAGAPPL
                     QTGALAEAGRRLGTAFQIVDDLLGIWGDPRTTGKPVHGDLLRRKKTLPVLAAVALDEGA
                     TARELARLLGPGTPPDAAAADRAAGLVEAAGGREFALQEAHRHAAAAHECLRGSGLAEG
                     AVGELVALSAYLLERQL"
     gene            complement(11120..12181)
                     /locus_tag="AS857_RS02890"
     CDS             complement(11120..12181)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016906849.1"
                     /locus_tag="AS857_RS02890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_058041508.1"
                     /transl_table=11
                     /translation="MYGKAFAPEYRGSLEDLSVNASLEEVLAKAVEQRQRAQLDGSALD
                     MAHAELAVAEASRRLGRVEDAERAWKASYRAARQAADLGAMAWAVWSGGTLARQRGALA
                     LARRWLAIAAELAERGDDIVARGYSLAGLAETGRIQGDYQAVGELHEKLLAEARRRGEA
                     RHTVWALEGIAQMHRNSGSYDTALAMFEEAAEISGGADDARGHAWALRGIADVLSLRGE
                     TERALALLSEAEGTCRRMKLVSALAYNHKMRGNVLFRAGRYAEAEECYRGALEEFREMA
                     EPRGAALARLGLVKSRARLGHDRAETAAELDDLHRTLGRIGLLHARRMVEAARAELGMA
                     AEPAASPAARPAA"
     misc_feature    complement(12408..12419)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(13193..13208)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.1"
                     /tool="antismash"
     gene            13246..>14473
                     /locus_tag="AS857_RS02895"
                     /pseudo=""
     CDS             13246..>14473
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014055542.1"
                     /locus_tag="AS857_RS02895"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="DUF692 domain-containing protein"
                     /pseudo=""
                     /sec_met_domain="DUF692 (E-value: 1.2e-93, bitscore: 309.0,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPSALKTLGTGIGWRPETADAVAAGPVRADWVEVVAENICPGH
                     LPGPLRELRERGTTVIPHGVSLGLGGADRPDLARLAALAERAEALGSPLVSEHIAFVRS
                     GGPLTGSPRIEAGHLLPVPRTHDALDVLCENVRIAQDMLPVPLALENIAALLPWPGEEL
                     TEGQFLAELVARTGVRLLIDVANLHTNHVNLGQDPAAALDELPLEAIAYVHVAGGVEQG
                     GLWHDSHAHPVTGPVLDVLAELAARVTPPGVLLERDDAFPAPEELAAELDAIRATVAGA
                     RRSSRQDRRRAVAHSV"
     gene            14683..15672
                     /locus_tag="AS857_RS02900"
     CDS             14683..15672
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR04222.1"
                     /locus_tag="AS857_RS02900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TIGR04222 domain-containing membrane protein"
                     /protein_id="WP_058041509.1"
                     /transl_table=11
                     /translation="MIAGIVVASLVTLLALVAPSAWLVVARRRALADPPPAQGRPELLE
                     VAYLLGGRSRVVDTVIAGMCDDGRISVNESGKLKAERAVAYNPVERALLGRCGAEWSTS
                     LRKVRTSLQFDPAVDALEGALVRRGMLVSPMAKQKWRRAADVQVGGLVLTAVGVVSLVL
                     MPVTFVVPFVVLDFLVAGIVLRVLCRPAGPNAALPTPCGKAFINLTPATGPWSVRFSAT
                     HPEGIAGVVAVHGADGPEPDQVFLSQLRQAALSSTSAGSAGSYSKSAKKSSSSSASSSS
                     HTSGGYACSGASSCSGHSGHSGHSSCSSSSCSSSSSSSSCGGGSSCSS"
     gene            15811..17430
                     /locus_tag="AS857_RS02905"
     CDS             15811..17430
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004956185.1"
                     /locus_tag="AS857_RS02905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phospholipase D-like domain-containing protein"
                     /protein_id="WP_058041510.1"
                     /transl_table=11
                     /translation="MARLRLRRLTRPAVSAAVSALALAALPAAPAFADSSATPHLDAVE
                     QTLRQVSPGLEGRVWERTAGNALDASSGDPADWLLQTPGCWGDATCAERPGTKRLLAKM
                     TENISRATRTVDISTLAPFPDGAFQDAIVAGLKKSVENGNKPKVRVLVGAAPVYHMNVL
                     PTKYRDDLRDKLGKAAGSVTLNVASMTTSKTAFSWNHSKLLVVDGQSAITGGINSWKND
                     YVDTTHPVSDVDLALTGPAAGSAGRYLDQLWTWTCGNKNNIASVWFAASDGASCMPTME
                     KDANPAAAPATGNVPVIAVGGLGVGIQDSDPSSSFRPDLPTAPDTKCVVGLHDNTNADR
                     DYDTANPEESALRALVASARSHVEISQQDLNATCPPLPRYDVRLYDALAAKLAAGVKVR
                     IVVSDPANRGAVGSGGYSQIKSLNEISDVLRNRLALLTGGQQGAKTAMCGNLQLATARS
                     SDSAKWADGKPYAQHHKLVSVDGSAFYIGSKNLYPSWLQDFGYMVESPEAARQLDASLL
                     APQWKYSQATATFDYARGICQG"
     misc_feature    15835..15837
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17509..18771)
                     /locus_tag="AS857_RS02910"
     CDS             complement(17509..18771)
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010473878.1"
                     /locus_tag="AS857_RS02910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_058041511.1"
                     /transl_table=11
                     /translation="MNVRTRTVHRALAGALAAAAMAAAALTAPAAAEAAGTTAADGRET
                     AAGHDRHAATRSAMEAQVAAGIPGVLGQARDDHGTWRGSAGIADRTTQRPRLAQDRFRI
                     ASVSKVFTSVVLLQLEAEGRIGLDDPVERWLPRVVRGNGHDGREITVRQLLNHTSGIYN
                     YTEDPAFQKLLGPDFLEHRFDDHTPDELVKTAMAHAPYFRPGGGWHYSNTNYVLAGMVV
                     EKVTGRSYATEIKRRIIRPLGLTATTLPGTAPELPGPHGRAYSTLQAEPAPGAKIYDVT
                     ELNPSWGGAAGEIISTTGDLNRFYGALIGGKLLPKAQQRELLTAVPVGDQAPGARYGLG
                     VLTAPLSCGVTVWMHTGGVHGSGTIASATADGRHTAAFNFNGDWTGDLGALVEAEYCGK
                     APSGGSALAGPQKTMTLMALR"
     misc_feature    19173..19185
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 22.92"
                     /tool="antismash"
     gene            19265..20068
                     /locus_tag="AS857_RS02915"
     CDS             19265..20068
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004956382.1"
                     /locus_tag="AS857_RS02915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_058041512.1"
                     /transl_table=11
                     /translation="MPYVRHWLRNSVLLFAVAIALGLVAVHTDLIQPHDLKLDRAVQTT
                     FRTEWLNVVMEGVSALASPIAGLLILAVWCGWLLFVRRRPVTAVSTFLVVAVGWNSTQI
                     AKAIVARPRPPREFMLDPEIGSNSFPSGHTAFTVAAFIAAYFLFRESRHRRTVAVVGVF
                     AVLLIAFSRWYVGAHYPTDTFGSVLIASSAIIFVTGVWHAWLLPRLYRIPLLERFGLDE
                     ELAELEAAEQHGGHHGHTRPVPPGRRRGGGGGTPTGGRHRRHASR"
     misc_feature    complement(20174..20188)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.9"
                     /tool="antismash"
     misc_feature    complement(20454..20468)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.48"
                     /tool="antismash"
ORIGIN
        1 cagctccagg aagatcagct ggacctgggg ggccgcgcgc agggtgtgca gctcgacctg
       61 gatgccgggc aggagggaca gggcctccac ggtccaaggg ctgagccagt cgccggtggc
      121 catctgggcc gtcgcctcgc ggaagccgtt gagccgggcg cggacgaact cgccccgctt
      181 ctcgggcagc cgcttgtagc cgcgggcgcc cgacagctcg ttgcggccgt cggactcgcc
      241 gccggtgaga cagaccgtca cggaggggcc gccgccgagg atcgactgct ccagctccgg
      301 gttcatgaag tagagggagt cgtcggggtg ggcgatgacg tggacgaacg actcggacgt
      361 cgtggccttc gcggggcgca ccggggcgcc gtcctgcgtg gccttcttct tcgcctccgg
      421 ggacagccac tgccaggcac ccaccgcacc ggctccgacg acgatgccgc cgcccgcgac
      481 ctggagtaca cgtcggcgcg gtatgtgccc aggcacaggt ttccccccac tctcctgcgc
      541 gtgatgcgcg ggtagaaaag caaaggggcg attagaacta atcgcccatg gatcatgagt
      601 tcgatcctat gaccggcaac ctgctgtttc cccgctgttt tgtaacagcc gtacgtcggc
      661 cgcatgtagt ttcgtaggcg gttgcgcaac accgccctac gggcgtgcca gggtgaccga
      721 cggtcgcgtg gcggtagcgg agcggcttat ggaaagcgcc ggtccggtcc gttcggggag
      781 ctgctcacgg agctgtgccg gggcggcccc gggaccggtc cgcggcggac gccgggcccg
      841 cccggggccg gttccggacg gacgggctcc gggcggggag tgcctcaggc ctccgcgccg
      901 ggcccgcccg cgtcgtggac gagcagggcg atctgcaccc ggttgttgag gcccagcttg
      961 gtgaggatgc gcgagacgtg cgtcttgacc gtcgccacgc tcatatagag cgcgccggcg
     1021 atctccgcgt tcgactgccc gcgcccgaca cagcccgcga cctcccgctc ccggtcgttg
     1081 agcgcggcca gcagcgcccg ggcccggtcg ccccgggtgt cccgctcccg ctccgtgacc
     1141 cgggtgatca gctgctgcgt gacggcgggg gagaggaccg gctcgccggc ggcgaccctg
     1201 cgcaccgccg cgacgatctc cgccggaggg gtgtccttga ggacgaagcc cgccgctccg
     1261 gcgcgcaggg cccgcagcac ctgctcgtcg gcgtggaagg tcgtcaggac gacgacctcc
     1321 ggggcgcctt cgcggcggcg cagctcctcc gtggcggcca ggccgtcgac cgacggcatg
     1381 cggatgtcca tcagcaccac gtcgggcgcg tgccggtcga cgagggcggt gacctccgag
     1441 ccgtcggcgg cctctccgac gatgcggatg tcgggcaggc cgcccagcat gaacgacagc
     1501 ccggcccgca ccagggggtc gtcgtccacg agcaggaccc ggatcggccg ggcctccggg
     1561 gaccgctggg cctgggcccc gggggagtgc gagggctcgg ggccgtgcgg cggctgcggg
     1621 gcgttcatgg ccgccacggt agccagccgt cgacgcggaa gccgccgtcg ggggtggggc
     1681 cgtgcgagag ccggccgccg gcgagggcgg cgcgctcggc cagcccgatg agaccctgcc
     1741 cggacccggg cacggatgct ccgctgccgt cccccggcgg attggtgatc ccgaccgtca
     1801 gccccgcctc cggggagccc tcgaccgtga tcctcaccgc cgcccctccg gcgtgcttac
     1861 gggcattggt cagcgcctcc tgcacgatcc ggtacaccgt gcggcccgtg gcctccggaa
     1921 ccgacggggc gtcggccacc cgctggtcga gcaccacctc cgtgcccgcc tgccgggact
     1981 cctccaccag ctcctccagc gccgccaggg tgggctgcgg gcggtcccct ccgccctccg
     2041 cgccgggggc gcgcagcacc ccgatcacct cgcgcagatc ctccagggcc tgatgcgcac
     2101 tgtcacggat caccccggcg gcccgggcga cctccgcggg cggcgcgtcc ggacggaact
     2161 ccagcgcccc cgcgtgcacg cacagcagcg acagccggtg cgccaggacg tcgtgcatct
     2221 cccgggcgat gcgctcgcgg gccaggcgct gggcctgctc agcccgcaac tgcgcctccg
     2281 cctcggcccg ccgggcgcgc tcgcgcagcg acaggaccag ctggcgccgg gaccggacga
     2341 acatgcccca gccgatgacg gtgaggacca gcagcaggcc cgtggcggtc gcggcgggga
     2401 acggcaggtc cgggtcggga cggatcgccg cctgcagcgg ctcgctgatc agcgcgagcc
     2461 ctcccacggc ggccacggtc cggaacggcc ggtgcacggc gaccgtgaac accgccacca
     2521 gcatcgcccc tgcggcgggc ggcacggggg tgctcaccac caccaggacc acggcgagcg
     2581 gcaccggcca ccggcggcgc atccacagcg cgacgcaggc cagggcgccc acgatctggt
     2641 cgaagaagag gagcgcgggc gaggcgcccg ggtccttgcg cagcgcctcg gcggccagta
     2701 tcccgatcac ggcggcgagg gcgatgcaga ggatgtcgac cgcccagtcg cgcacactgc
     2761 gcgccgtgcg gggctgcacc tccgccgtct cctcggtctt cacgtccatg agcagccaat
     2821 ttaccgatgc ggcgggcgga ccggaggcgc cggacggagg gccgatacca aagttgtacg
     2881 aggcgggacc ttggatgatc cgggggcctg cgggctgcta cttcggtcgg cgccgcgcag
     2941 ccttccgggc gatgaccggg gcggggcggc ggcaggagca tggcgggtat gaagaagctg
     3001 ctcgaaggcg tcggcgtcat cctcgtcctg caggggctgg gcggcgtcgt ccacggactc
     3061 accggctggt tccactactg ggtggtcgtg cgttacctcg gtttcctcga cggctacgag
     3121 atgtacgcga gcatcgtcct cgccgtcatc ggtacggctt tggtcatagc ctcggacagc
     3181 gtcgaggccg agtccgcgcg agaatgaccc catggctgac aggacttccg gcacttcgga
     3241 actggtcgag ctcctcggtc tccaaccgca cgtcgaggga gggtggttcc gcgagacgtg
     3301 gaggacctcg cgcgaggcgg tccccgacgg ctacggcggc ccgcgggcct tcgccaccgg
     3361 catctactac ctcctccacc ccggtgaggt ctcccgctgg caccgcgtgc gctccgacga
     3421 gctgtggctg tggcaccgcg gcggcccact gctgatgcgg ctcggcggct ccggcgatac
     3481 gcccgacggg aaggatgccg ccgaagtggt cgtcggaccc ggcgtcgagc gcggcgagca
     3541 accgcagttc ctggtgcccg gcggcgtgtg gcagtcggcc ggtcccgcgg gggacgagcc
     3601 ggtgctggtg acgtgcgtgg tcgcaccggg cttcgactac gaggacttcg aggactccga
     3661 ggatcccgag gattccgcga gggggtgacg gcgccctcgc ccacccccta ctgaggtatc
     3721 accccagggt tggctccctg gggtgacgca ggttcggaca ccctctttct agctttccct
     3781 cagtcacgga acgggacgag ggagagacag tcatgggccg cttcaagcgc acgctgatcg
     3841 ccgcagctct ggccgccacg gtcgtggccg gcacggccgg ctgggccgtc agcgacgagc
     3901 aggccgtggt cagcggcccg cccgccggcg ccgaggcctg gcgtgcggac cactccctcc
     3961 accgcgagct gccggacccg gcgacggcgg caccgcgtac ggtcgccgcg ttcttcgccg
     4021 gtctcaccga ggcccagcgc aaggacctgg cggcccgtca cgcgctggtc gtcggcaacc
     4081 tcgacggtgc gcccgtgccc ctgcggtacg aggccaacgc ccgggcgata gccgccgagc
     4141 gggagaagat gcaggcccgg gccgcggacc ccggcctgac ccgcgccgcg cgggaagagg
     4201 cccgcgagcg ggccgaccgc tgcgagcggc tgctcgcgcc gggccgccgc atcctggcct
     4261 tcgacccgcg cggccgcggc caggtcgccg aggtgtacgg cgatctggcg gccgcccggc
     4321 acaccgccgt gatcgtgccc ggctcggaca tcgacctccg caccttcgac cggacgaagg
     4381 accgctacgg cacccccacc gggatggccg cctccctgcg ggccgagatg gagcgcaggg
     4441 cacccggcac cccgaccgcc gtcatcgcct gggccggcta caccacgccc gtgggcctcg
     4501 gccttgacgc cgccaccggg cgcctcgcgc aagccggggc cgtgcgcctg gagcgcctgc
     4561 tcgccgggct ggcggcggcc gccgcctctc ccgccgcacc gccgccctcc gtgttctgcc
     4621 acagctacgg ctcggtggtc tgcggcctgg ccgccccgtc cgtcgaccgc accgaggccg
     4681 ccgacctcgt ggcgctcggc agccccggca tgcgcgccga ctcggtggcc ggactgcaca
     4741 ccggcgcccg cgtctgggcc gccgcgcgca actcctcgga ctggataggc aacgtcccca
     4801 acgtcgacct cttcggcctc ggccacggca ccgaccccac gtccgcggag ttcggcgccc
     4861 gcgtcgtccc cacacacggc gcccacggcc acaccggcta cttcgccccc ggcacggact
     4921 ccctgcgcaa cttcgcggac atcgccctcg gcgcctacgc ctagacctgg accgccaaga
     4981 tttgactgcc aaggtttctt tgcaaagaaa ccttggcagt ctagagtcgg gggaatgacc
     5041 catgtcgttc tcgacgccaa gggcctgcgt gccctggctc accccgtacg cgtgcaactc
     5101 gtgggcctgc tgcggctgta cggcccctcg acggcgaccc ggctcgccga gcgcctcggc
     5161 ctggcctccg gggcgaccag ttaccacctc cggcagctcg ccgccgcggg cttcgtcgcg
     5221 gaggacgcgt cgctgggcaa tgcccgcgag cgctggtggc gtgccgtcca cgaggccacg
     5281 gtgatcgacg acgacgagct cgccgagcag gagcccgagg ccatgctcgg ctacgtccag
     5341 ggcgtcgtgg ccgcccacac cctccgcacc cagctggccg tcgccgcgta cccggccctg
     5401 ccgaagccct ggcgggacgc gttcgacatg agcgactgga acctgcggct caccccgcag
     5461 gaagccgcgg agctgaccgg ggagctccgg gcggtcgtcg agcgctaccg gcagtacgcg
     5521 tccggcgcgg acgcccccgc ggacagcgag cccgtcgcgc tcaccctgca cctcctgccc
     5581 gaccctgcag tcgcggaggg ccgtacggaa ggcggcgcgg gagccggcgc ggacaggcgg
     5641 gaaggagcgt gaccccgccg gcgccgcggc gtggccggat atccggccgt cttccgtacc
     5701 cccgacgccc gggcggagcc ctcggcggcc cctccgcagg tcgcagcgtc cgcccgctcg
     5761 ctggagtcct cgcggcaacg gccgtctccc tgacgggcac gcgcgtctcg gcggtcgccc
     5821 tgccgtggtt cgtgctcgtc accaccggca gcgccgcgca gaccgggctc gtcgccttct
     5881 gcgagatgac cccgtacgtc gtggtcaaga tgctcaccgg ccccctggtt gaccgcgtcg
     5941 gaccgcgcgt cgtctcctgg gcgaccgact ccctcagcgc cgccgctgcc gcgctgatcc
     6001 ccctgctcca tgccctggac ctgctgccgt tctggctgct gctcggcctc gtcgcggtga
     6061 tcggcgccgt gcgcgggccc ggcgacctgg ccaaagcgat catggtgccg gaggcggcgg
     6121 agcgcagccg ggtctccctg gaacgggcta ccggcctttc cggcgtcacc gagcgcctcg
     6181 cctccacggt cggcccagcg gccggcggcg tgctggtggc gctgctcggc ccgatggccg
     6241 gcctggtcgt caacgccgtc tgcttcgccc tgggttcgct cgtgatcgcg ctcgcgctcc
     6301 cgcgcggcat gggcctcgcg gtgccgtcgg gcgacgcgcc cacggacggc ggtacgggcg
     6361 aaccggcagg ctactggcgc cgtttcggcg aaggcttcgc cttcctgcgc ggcgaacccc
     6421 tgctgctcac gatcatcgtc acggcaggca tcaccaacct cctcgacgtg ggcttcacgg
     6481 ccgtcctcgt ccccgtgtgg gccgagagct ccggcggcgg ccccgcggcc atcggcctca
     6541 ccagcagcgc ggcgggcgtc gcggccgtct gcggcagcct cgtggccgct gcgctcgccc
     6601 cccggctgcg tcgccgcccc gtgttcttcg cgggcttcct gctcgcaggg gcaccgaggt
     6661 tcgtcgtgct cgcctgcggc gcgccgttgt gggtggtgct cgtggtgttc gccgtcagcg
     6721 ggttcggcgg cggcttcctc aaccccatcc tcggtgccgt gtccttcgag cgggtgccgc
     6781 gcgccctgct gggccgggtg cgggcgctgg gcgactccct ggcctgggcg ggcatccccc
     6841 tcggcggcct gctcgccggg ctcgccgtca cgtccgcggg gctgacgccc gtcctcctgg
     6901 tgggaggggc gatgtacttc ctcaccacca acctggccgg actgcgcccg gagtggcgcg
     6961 agatggaccg ccggcgcggt gccggcaccc ctcgcgaagc gccggaaggc gtcgccgtgc
     7021 gaagttgatc atctccgacc tgaggctgat ggcgggacgt gtcacggccg cataacgtga
     7081 tgatcatgtt gtggaaatcg cggaagacat cgcggcggtc cttcgtggcc gccgcgctcc
     7141 tcatggcctt cgccgcaccc cagatgcccg ccgtggccgc ggcggcggaa cggacccccg
     7201 ggccggcggc gcccggaacg ccggccgagg tgccggcgcc cacgggcaag atgccggtcg
     7261 ggacgaagac gctgcacctc gtcgacacct cgcgccccga cccgtggaag cccgccgccg
     7321 gcaagcggca gctcatggtc tcgctctggt acccggcgcg gcaccagggc gacaagaacg
     7381 ccccctacgt gtcgaaggag ctctccaagg cggtcctcgg caaggaggat ctcgccggcg
     7441 tccgcacgaa ctcgaccctg gacgccgagc cggccggcaa gccccggccg ctggtcgtcc
     7501 tttcgccggg cttcgggatg agccggctga ccctcaccgc gctcggcgag gacctcgcgt
     7561 cccgcgggta cgccgtggcc gcggtcgacc acacctacga ggccccggtc gagttccccg
     7621 gcgggcgcat cgagacctgt gagacctgcg cgaagccgga catggccgcc gtcgtgcgga
     7681 accgggcgaa ggacttctcc ttcctcctcg accggctgac cgcccccggc agcccgctcg
     7741 ccgtcgaccg cggccggatc gccgtggtcg gccactccat cggcggcgcg agcgcggtgg
     7801 aggccctgcg cggcgacaag cgcgtggacg ccgccgtcaa cctcgacggc aacttcccca
     7861 tcgacctgcc cgccgagggg ctgaagaagc ccgtgatgct cttcggtgca cagcggtccg
     7921 gcgacgacgc ggagaactgg aacaagaact ggcagcggct gacgggctgg aagcgctggc
     7981 tcgacgtgcc cgaaggcggc cacctgacgt tcacggacgc cccctggatc gcggaccggt
     8041 tcggaatgcc cgaccagatc ccgccggagc aggtccacgg cgcctacggc agcctgcacg
     8101 gcatccgctc gaccgcgctc acccgtgcgt acgtgaacgc gttcgtcgac cggcacctgc
     8161 gcggcacgcc gagcccgctc ctcgaccggc cgtccgcggc ctacccggaa gtcaccgtcc
     8221 tgaagaagaa gtaacgcgca tcctcgggag acccgggggt ggcaccagtg ccacccccgg
     8281 aacggatacc agcggggtcg atcgcggccg ccccgcccgg gagcatcgaa ccgtcaccac
     8341 gcaccaggag gttcgatgtt cgagctcagg aaatcgcggc gcaccgtacc ggcggtcttc
     8401 gcactctccg ccgtgtcggc cgcgctcgcc gcggtggtcg cggccgcagt gctcccggcg
     8461 ggagcagccg ctgcgcagca gggcgcgacc gcgcagccgc gcccggccac ggccgtgacc
     8521 gtgcccgagc ggtacgcctc ccagaagctg gcctggcagc cctgccccga gctggccacc
     8581 atggagtgcg cggagatgac cgtcccgcgc gactggcacg ccccggacgc cggcaaggac
     8641 ctcacgatcg ccgtgtcccg cgtgcgggcg agcgaccccg cccaccggcg cggggtgctg
     8701 atgatggccg cggggggacc cggcggcaag gggctgctgc ggccggccgg cgtcgcccgg
     8761 aaggcgcccg cgatcggcgc cgtccacgac atcgtcagct tcgaccagcg cggcgtcggc
     8821 aggagcacgc cgctgcagtg ccagacccag gacgagctcg acgccttctt cgcgggcgac
     8881 ttccgcgacc gctcgcccgc cgccgtgcaa cgcgtcgtgg acaactcccg caagctcgcc
     8941 gacgcctgcc gcgcgaagca cggggacctc ctcccgtaca tcaccaccga gcagaccgtg
     9001 cgcgacatgg acctcttccg cgccctgctc ggcgagcgga agatctccta ctacggggcc
     9061 tcctacgcga ccatggtcgg cgcgtactac gcctcgctct tcccgcagcg cgtcgaacgc
     9121 gccgtcctgg acagcaacat agccttcggc ggcacctggg aggacttcga gaagggccag
     9181 ccgaagagct tccagcgccg cttcgagcag gacttcctgc cctggctcgc gaagaacgac
     9241 gccacctacc actacggccg caccgcggcc gaggcgaagg ccacgtggga gcggcggcgc
     9301 agcgcgctgc gcgaccaccc gctcagcccg ggcgagggca agggcaggac cctcgacccc
     9361 aaccgcttcg acagcggcac catccaggcg atctacgact cgcaggaggg cttcccggcc
     9421 ctcgcgaagg cgctcgccgc gctggagcac tgggacacgg cggcccccgc cgagcggaag
     9481 ctcgtcgaca ccgtcttcgg ctcctacctc ggcaccaact tcttcgccga gttcctctcc
     9541 gtgacctgcg ccgacacccc gtggaaccgg gacaccggct cctggatccg gcgcagcgcc
     9601 gaggacaccg ccaagtaccc cctgatgggt gcccgggagc tcgccttcgc ctccgcgtgc
     9661 gcggcgtggc ccgcctcccc ggcaccgcgc gtcaaggtca ccggcaaggg cctgccgccc
     9721 gtcctgatgc tcaactccct gcacgacccg gccacgtact acgaggctgc gcagcgcgcc
     9781 caccgggacc tgcgcggctc gcgcctggtc acggtcaccg gcggcgacca cggcgtctac
     9841 ctgggcggca gcgcctgcgc cgacggcatc gtgaacaagt acctcctctc cggagaactg
     9901 cccgcccggg acgtcacctg cgaggacgcg ccgctgccgg cgccggcggc gaagtagccc
     9961 gcagcggggc cgctcgccgc aactacggct ggagcagcag ctacagctgc cgctccagca
    10021 aatacgccga gagcgcgacg agttcaccga ccgcaccctc cgcgaggccg gagcctcgca
    10081 ggcactcgtg ggcggccgcc gcatggcggt gtgcctcctg cagggcgaac tcccggccgc
    10141 cggccgcctc gaccaggccg gccgcgcggt ccgcggctgc ggcgtccggg ggcgtgcccg
    10201 ggcccagcag ccgggccagc tcgcgggcgg ttgccccttc gtccagggcg acggccgcca
    10261 gcaccggcag ggtcttcttc cgccgcagca ggtcgccgtg gaccggcttg cccgtcgtcc
    10321 gcgggtcgcc ccagatcccc agcaggtcgt ccacgatctg gaacgccgtg ccgagccgcc
    10381 gcccggcctc cgcgagggca cccgtctgca ggggcggggc gcccgccagc accggcccca
    10441 gggacagggc gcagccgagc agggcgccgg tcttgcgggc cgccatcgcc tcgtactccg
    10501 gtatgccgac cgctccccgc cccgtccacg gacggctctc gaacagcagg tcgtccgcct
    10561 gcccgcgcac cagctcgccc aggcagtcgg ccaggtgcgc caccgcccgg ccggtgtgct
    10621 cgcccccggc ctccgccacc gtccgcacgg ccagcgcgaa cagggcgtcg cccgtcagaa
    10681 cggccggtcc ggtgccgaac gccttccacg tcgcgtcccg gtgccgccgc cgctcgtcgc
    10741 cgtccatgat gtcgtcgtgc accagcgaga aggtgtgcac cagctccacg gccaccgccg
    10801 cctgcaccgc cgtcccgagg ggagcgccca ccgcctccgc gccgagcagg gcgaacgcct
    10861 ggcggacgcc cttgccgccg ggggaggggc tcggcgtgcc gtcggcctcg caccagccga
    10921 aggagaaggc cgccatgcgg gccggcagcg ggtgcagcgt cgccacggcg gctctgagcg
    10981 cgggctcggc cagcgcccgt gcgcgggcga gcgtctgggg agcgggggtc cggagtgcgg
    11041 tctgcggggg cacggggccg gcctgcgtgg gcatggtctt tctctctcct gtcgtgggct
    11101 gccgcggaag gacgtgctgt caggcggccg ggcgggccgc cggggacgcc gcaggctccg
    11161 ccgccatccc cagctccgcg cgcgccgcct cgaccatccg ccgggcgtgg agcaggccga
    11221 tccggccgag cgtacggtgc aggtcgtcca gctcggcggc ggtctcggcg cggtcgtgcc
    11281 ccagccgggc ccggctcttg accagtccga gccgggccag ggcggcaccc cgcggctccg
    11341 ccatctcccg gaactcctcc agcgcgccgc ggtagcactc ctcggcctcc gcgtaacggc
    11401 ccgcccggaa caggacgttg ccgcgcattt tgtggttgta ggccagagcg ctgacgagct
    11461 tcatccgccg gcacgtcccc tcggcctccg acagcagcgc gagcgcccgc tcggtctctc
    11521 cccgcaggga cagcacgtcg gcgatcccgc gcagcgccca cgcgtggccg cgggcgtcgt
    11581 cggccccacc cgatatctcc gccgcctcct cgaacatggc cagcgcggtg tcgtacgagc
    11641 ccgagttgcg gtgcatctgc gcgatgcctt ccagcgccca cacggtgtgc cgggcctcgc
    11701 cgcggcgtcg cgcctccgcc agcagcttct cgtgcagttc gccgacggcc tggtagtcgc
    11761 cctggatgcg tccggtctcg gcgagccccg ccagggagta gccgcgggcc acgatgtcgt
    11821 cgccccgctc ggcgagttcg gcggcgatgg cgagccagcg ccgggccagg gccagggctc
    11881 cgcgctgccg ggcaagcgtg ccgccgctcc acacggccca ggccatcgcc cccaggtcag
    11941 ccgcctgccg cgcggcccgg tagctcgcct tccacgcgcg ctcggcgtcc tccacccggc
    12001 cgagccgccg gctcgcctcc gcgacggcca gctcggcgtg cgccatgtcg agggcggagc
    12061 cgtccagttg ggcacgctgc cgttgctcga ccgccttggc cagcacttcc tcgagcgagg
    12121 cgttcacaga gaggtcttcc agggagcccc ggtactcggg ggcgaatgcc ttgccgtaca
    12181 tggttcagcc tcacttcggg atcactcggg tggggcaggg ggcgccctac cgttgatcaa
    12241 gaagctatgg cctcgaacca ccctgagtag tcagaccagg aggcggcgtt ccgtacatct
    12301 gaggtccggt gcagacggca cgggtcatac gagagatgta cggacggcgg cggacggggc
    12361 atgcgcgagc gctcgctcgg tgccctgatg gacaagtact gcgcgaggcg ttcgtgtgcc
    12421 ttgaagtctc ctgggaggaa gggctgttgt ggacgtacag cacgggcgga accgtgaacg
    12481 gaggcccgca gggaacgcgc ggcggaattc cgccgggagt acgaccgtgg ttcgcagcgc
    12541 ccggacttgt cagccggccg gtgccgttcc ggggcgggcg gcaggattcc ccttttccgc
    12601 gctcccggca ttgcccgccg tatcccctcc cacaggcccg gccgctcccg gcacctgtcc
    12661 ctgcgggggc agtgccgaag cctgcccgtt tcctccgggc gacttcgacg ggacgggccc
    12721 ggacgggccg ccgttgacgg aacccgtcgt ggtgttgtgc gaggcggacg gcttgcggct
    12781 cggtgatggc tttccccggc cgttcgagcc ggccgacgtc ccgcccattc cgctgccgtt
    12841 cccccggccc gtggtcgtcg agccctgctc acccccctgc gaggtggcgc tctggctcgg
    12901 cttgacgtgg ttgccgtcgt tcactgccgc tttcacaccg atgactgcgg ccacaatggc
    12961 accggcggcc ccgatgaagg ccgcgacgat tgctacgaaa ttgcccggtc cattggcgga
    13021 accccgacct ccgcccgggc cttgaccacc gtattggctc actcgacccc ccgaggtgaa
    13081 aacccgaggg caaatgtacg cgcgaaatcc acgagtgtgc tatgcaccgg accggggcgg
    13141 atgctgtttc cctgccgcag gatttgtaca gtgtgccgcg gggaaagccc gctggtacag
    13201 gcgttcggct ccacggggga gctcgggaaa gacaggggcg gggccatgag tgagccgagt
    13261 gcgctcaaaa cactggggac ggggatcggc tggcgcccgg agacggccga cgccgtggcg
    13321 gcgggcccgg tccgcgccga ctgggtggag gtcgtcgcgg agaacatctg cccgggccac
    13381 ctccccggcc cgctccggga gctgcgcgag cgcggcacga cggtgatacc ccacggggtc
    13441 tccctcggcc tcggcggcgc cgaccggccg gatctcgccc ggctcgccgc gctcgccgag
    13501 cgcgccgaag ccctcggctc gccgctcgtc tccgagcaca tagccttcgt ccgctccggg
    13561 ggaccgctga ccggctcccc gcggatcgag gccggccacc tgctgccggt gccccgcacc
    13621 cacgacgccc tggacgtcct gtgcgagaac gtccgcatcg cccaggacat gctgcccgtc
    13681 ccgctcgcgc tggagaacat cgcggccctc ctgccctggc ccggcgagga gctgaccgag
    13741 ggacagttcc tcgccgagct ggtcgccagg acgggcgtgc ggctcctgat cgacgtcgcc
    13801 aacctccaca cgaaccacgt caacctgggc caggatcccg cggccgccct ggacgaactg
    13861 ccgctcgaag ccatcgccta cgtgcatgtg gccggaggcg tcgagcaggg cgggctgtgg
    13921 cacgacagcc acgcccaccc ggtgaccggc cccgtcctcg acgtcctcgc cgagctggcc
    13981 gcccgcgtga cgcccccggg cgtcctcctg gagcgcgacg acgccttccc cgcacccgaa
    14041 gagctcgcgg cggaactgga cgcgatcagg gcgacggtgg ccggtgcccg gcgctcctcc
    14101 cggcaggacc ggcggcgggc ggtggcgcac agtgtctgaa accacgtctg aaaccacgtc
    14161 tcaaaccgtg tccgaaaccg cgtccgagac cgcctccgac gccgcccggc ggcgcctcgc
    14221 gcacgcccag cacgccctgc tctcagcgct cgtcgcggac gcacccccgc cgcccggctt
    14281 cgacccgcaa cggctgcggg tgcagcagca ggcgctgctc ggcaagcgcg cggacgtcgt
    14341 cgcgaaggtc gagccggagc tgcccgagat cctcggggcg gacttccggc ggctcttcct
    14401 cacctatgcc cgaggccgtc cgatgagcga cggctaccgc caggacgccc tcgacttcgc
    14461 cgaggcgctc ctgaagaccg acggtatccg gatcgatggc atccgggccg atggcatccg
    14521 ggccgacggc atcctcaccg cccccgggcg gcgggagcgc ctcgcggcgt ggacggccgc
    14581 ccggcacgcg gcgccgtccg ccggccctgc cccgcttcct gctcgcctgg cgtcggcctg
    14641 gcacaccttg cgctcgcgcg tgacccgaaa ggcaactgcc ctatgatcgc cggcatcgtc
    14701 gtcgcctccc tggtgaccct ccttgccctc gtagccccgt cggcctggct cgtcgtcgcc
    14761 cgccgccgcg ccctcgccga cccgccgccc gcacagggcc ggccggagct gctggaggtc
    14821 gcgtacctgc tcggcggccg cagccgggtg gtggacaccg tcattgccgg catgtgcgac
    14881 gacgggcgga tatccgtgaa cgagagcggc aagctcaagg ccgagcgggc cgtcgcgtac
    14941 aaccccgtgg agcgcgccct gctgggccgc tgcggcgccg agtggagcac ctccctgcgc
    15001 aaggtccgga cgtcgctgca gttcgatccg gccgtcgacg ccctcgaagg cgccctcgtc
    15061 cggcgcggga tgctggtgtc gccgatggcg aagcagaagt ggcggcgcgc cgcggacgta
    15121 caggtgggcg ggctcgtcct caccgccgtg ggcgtcgtgt ccctggtcct catgcccgtg
    15181 acgttcgtgg tgcctttcgt cgtcctcgac ttcctcgtcg ccggcatcgt gctccgcgtc
    15241 ctgtgccggc cggccgggcc gaatgctgcg ttgcccaccc cgtgcggcaa ggcattcatc
    15301 aacctgacgc cggcgaccgg cccctggagc gtccggttct ccgccacgca cccggagggc
    15361 atcgcggggg tagtcgccgt gcacggcgcc gacggacccg agccggacca ggtgttcctg
    15421 agtcagctga ggcaggcggc tctgtcgagc accagtgcgg gcagcgcggg ctcctactcc
    15481 aagagcgcga agaagtcctc ttcctcctcc gcgtcctcct cgtcccacac cagcggcggg
    15541 tacgcctgct ccggcgcatc gagctgttcc ggccactccg gccactccgg tcattcgagc
    15601 tgctccagct ccagctgctc ctcctccagt tcgagttcca gctgtggtgg aggcagcagc
    15661 tgcagctcct gaacggaacg ttccgggcaa ctggtacctt caccccggtg atcatccgca
    15721 gtgccggtca acggcgctgc ggatcgccgt gcgcgttccg ccgcgcggcg cgttcccggt
    15781 cacctccgca cccccgatca aggaagcaca ttggctcgcc tccggctccg ccgtttaacc
    15841 cgtcccgccg tctccgcagc ggtctccgcc ctcgccctcg ccgcgctccc cgcggccccg
    15901 gcgttcgccg actcctccgc caccccgcac ctcgacgccg tcgagcagac gctccgtcag
    15961 gtctcgcccg gcctcgaagg gcgcgtgtgg gagcgcaccg ccggcaacgc gctggacgcc
    16021 tcctccggtg accccgccga ctggctcctg cagacccccg gctgctgggg cgacgccacc
    16081 tgcgccgagc gccccggtac gaagcggctg ctcgccaaga tgaccgagaa catctcccgg
    16141 gccacgcgca ccgtcgacat atccaccctg gctcccttcc ccgacggggc gttccaggac
    16201 gcgatcgtcg cgggcctgaa gaagtcggtg gagaacggca acaagccgaa ggtccgcgtt
    16261 ctggtcgggg ccgcgccggt ctaccacatg aacgtgctgc ccacgaagta ccgcgacgac
    16321 ctgcgcgaca agctcggcaa ggccgccggc agcgtcaccc tgaacgtcgc gtcgatgacc
    16381 acctcgaaga ccgccttctc ctggaaccac tccaagctcc tcgtggtgga cgggcagtcg
    16441 gcgatcaccg gcggcatcaa cagctggaag aacgactacg tcgacaccac ccacccggtg
    16501 tccgacgtcg acctcgccct gaccgggccc gcggccgggt ccgccggccg gtacctggac
    16561 cagctgtgga cctggacctg cgggaacaag aacaacatcg cgagcgtctg gttcgccgcg
    16621 tccgacggcg cctcctgcat gccgacgatg gagaaggacg ccaaccccgc cgccgccccg
    16681 gccaccggga acgtccccgt gatcgccgtc ggcggtctcg gcgtcggcat ccaggactcc
    16741 gacccctcct cgtccttccg gccggacctg ccgacggcgc ccgacaccaa gtgcgtcgtg
    16801 ggcctgcacg acaacaccaa cgccgaccgc gactacgaca cggccaaccc cgaggagagc
    16861 gccctgcgcg ccctcgtggc cagtgcgcgc agccacgtgg agatctccca gcaggacctc
    16921 aacgccacct gcccgccgct cccgcgctac gacgtccggc tctacgacgc gctcgcggcg
    16981 aagctggccg ccggcgtgaa ggtccgcatc gtggtcagcg accccgccaa ccggggcgcg
    17041 gtcggcagcg gcggctactc gcagatcaag tcgctgaacg agatcagcga cgtcctgcgc
    17101 aaccgcctcg cgctgctcac cggcggtcag cagggtgcga agacggccat gtgcggcaac
    17161 ctgcagctgg ccacggcccg cagctcggac agcgccaagt gggccgacgg caagccgtac
    17221 gcacagcacc acaagctggt gtccgtggac ggctcggcct tctacatcgg ctcgaagaac
    17281 ctctacccgt cctggctgca ggacttcggg tacatggtgg agagcccgga ggccgcccgg
    17341 cagctcgacg cgagcctgct ggccccgcag tggaagtact cgcaggccac ggcgaccttc
    17401 gactacgccc gcgggatctg ccagggctga tccccggcgc tcccgtacgg acctgcggcc
    17461 cgcggctggt gtcagccgcg ggccgcaggc gtaccgtgcg cgggtgcgtc agcgcagcgc
    17521 catcagcgtc atcgtcttct gcggcccggc gagggcggac ccgcccgacg gggccttgcc
    17581 gcagtactcc gcctcgacca gcgcgccgag gtcgccggtc cagtcgccgt tgaagttgaa
    17641 ggcggcggtg tgccggccgt cggcagtggc actggcgatc gtgccggagc cgtggacgcc
    17701 gccggtgtgc atccagacgg tcacgccgca cgacagcggg gccgtgagga cgccgaggcc
    17761 gtagcgggca ccgggagcct ggtcgccgac gggcaccgcg gtgagcagtt cccgctgctg
    17821 cgccttcggc agcagcttcc cgccgatgag ggcgccgtag aagcggttga ggtcgccggt
    17881 ggtggagatg atctcgccgg cggccccgcc ccacgacggg ttgagctcgg tgacgtcgta
    17941 gatcttcgcg ccgggagcgg gctcggcctg gagcgtgctg taggcccggc cgtgcggccc
    18001 cggcagttcg ggcgccgtgc cggggagggt ggtggcggtg agccccaggg gccggatgat
    18061 gcgccgcttg atctcggtgg cgtacgagcg gcccgtcacc ttctcgacga ccatgccggc
    18121 gaggacgtag ttggtgttgg agtagtgcca gcccccgccc ggccggaagt acggtgcgtg
    18181 cgccatcgcg gtcttcacca gctcgtccgg cgtgtggtcg tcgaagcggt gctcgaggaa
    18241 gtcggggccg agcagcttct ggaaggccgg gtcctcggtg tagttgtaga tcccgctggt
    18301 gtggttgagc agctgccgga cggtgatctc ccggccgtcg tgcccgttgc cccggacgac
    18361 gcgcggcagc cagcgctcga cggggtcgtc caggccgatc cggccctccg cctccagctg
    18421 gagcaggacg acggaggtga agaccttgct gacgctggcg atgcggaagc ggtcctgggc
    18481 gaggcggggc cgctgggtgg tgcggtcggc gatgccggcg gagccccgcc aggtgccgtg
    18541 gtcgtcccgg gcctgcccca ggacgccggg tatgccggcc gcgacctggg cctccatggc
    18601 gctgcgggtg gcggcgtgcc ggtcgtggcc cgcggcggtc tcccggccgt ctgcggccgt
    18661 cgtcccggcg gcttcggccg cggcgggggc ggtgagggcc gccgcggcca tcgcggcggc
    18721 ggccagtgcc cccgccaggg ctctgtggac ggtgcgggtg cgtacgttca tggcaggtgg
    18781 cccctctgct ccgacggtgt gctgacaccg gacaggacac cgtcaagtcg cgtggggttg
    18841 aagggccttg tgggcgggga gcgggatccg gccagcggaa tgcggcgctc gcggagtgag
    18901 acacggcaca aatcccctcg tccgggaacc gccggccgcg ccgcggcgtc gagggctgct
    18961 gccccggccc cggcggctcc gtccacgatc ggctgaatcg ccgcccgtac ccccgcctcc
    19021 gggtccggcc gggtggtcac cgtcggatat aactccctca cgcagggtgc gtcgccggtg
    19081 gtgggcggcc cggggcgcgc ggccgccggc ggcgtccggg gcgggcgtcc cgaagggtgc
    19141 gtgtgcggcg cgtgtagctt tgccgtacag ccgtgccgtt gtcacccctg cggcaggcat
    19201 tcgtcacctt cgcgtgtact gccgtgccgg taccgcccta ccgaatacaa aggacgcccc
    19261 acccatgccg tacgtgcgcc actggttgcg caactcggtc ctgctgttcg ccgtcgcgat
    19321 cgcgctgggc ctggtagccg tgcacaccga tctcatccag ccgcacgacc tgaagctgga
    19381 ccgcgcggtc cagaccacct tccgcaccga gtggctgaac gtggtcatgg agggggtcag
    19441 cgctctcgcg tccccgatcg ccggcctgct gatcctggcg gtctggtgcg gctggctgct
    19501 gttcgtgcgg cgccggccgg tgacggcggt ctccaccttc ctcgtcgtcg cggtcggctg
    19561 gaacagcacc cagatcgcga aggccatcgt cgcccggccc cggccgccgc gggagttcat
    19621 gctggacccc gagatcggct ccaacagctt ccccagcggc cacaccgcct tcacggtcgc
    19681 cgcgttcatc gccgcgtact tcctcttccg ggagtcccgc caccggcgga ccgtggccgt
    19741 cgtcggcgtc ttcgccgtac tgctcatcgc gttctcccgc tggtacgtcg gcgcccacta
    19801 cccgaccgac accttcggct cggtcctgat cgcctcgtcc gcgatcatct tcgtcaccgg
    19861 cgtctggcac gcctggctgc tgccgcggct ctaccgcatc ccgctgctgg agcgcttcgg
    19921 cctggacgag gagctcgccg agctggaggc cgcggagcag cacggcggcc accacggtca
    19981 cacccgcccc gtgccgcccg gccgccgccg cggcggcgga gggggcacgc ccacgggggg
    20041 acgccaccgc cggcacgcct cccgctgacg gccgcggcac cgaccgcggc accgaccgcg
    20101 gcaccgaccg ccgtaccgac agggacctcg cagggctgaa gccccgcgtg gtccctgttc
    20161 tccttcgcct tccgaatttc tggaacaggt tctacggtgt gcgccgtcag cgcggcatac
    20221 ggcgagcacc cctggagggg ccgtggacct cgaatacacc ccggaacagc ggcgcttccg
    20281 cgccgagctg cgggactact tcgccgggct ggtcgcaggc cgcgcccacg cccgccacga
    20341 cgacccggcc gagcagaagc gcttctaccg cgccacgatc cgccgcctcg gcgcggacgg
    20401 ccgtctcggg gtgggctggc ccgccgagta cgggggcagc ggccggaccc cgatggaaca
    20461 gttcatcttc ttcgacgagg ccgcacaggc gggcgtgccg ctgcccctga tggcgctcaa
    20521 caccgtcggc cccaccctca tgcagttcgg cacggacgag cagaaggcgt acttcctgcc
    20581 ccggatcctc tccggcgagc tcgacttcgc catcggctac agcgagcccg gcgccggcac
    20641 cgacctcgcc tccctcacga cgcgggccgt gcgcgacggt gactcctacg tcgtcaacgg
    20701 ccagaagatc tggaccacca acggcgacac cgccgactgg atctggctgg ccgtccgcac
    20761 cacccccgtc accgacggca caccgccgca caagggcatc accctcctcc tcgtgccgac
    20821 cagcgccccc ggctactcct gcaccaccat caacaccctc gcctcccaca gcaccaccgc
    20881 cggctactac gagaacgtcc gcgtccccgt ccgcaaccgc gtcggcgagg agaacgaggg
    20941 ctggcggctg atcaccactc agctcaacca cgagcgcgtc accctcgccg cccacggcac
    21001 cacggccgcc ggcgccctgc gcgacgtacg gcgctgggcc gccgccacca agctcgccga
    21061 cggccgccgc gtca
//
