LOCUS       NZ_LNBE01000001        21068 bp    DNA     linear   CON 29-MAR-2024
DEFINITION  Streptomyces roseifaciens strain MBT76 scaffold_1, whole genome
            shotgun sequence.
ACCESSION   NZ_LNBE01000001
VERSION     NZ_LNBE01000001.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces roseifaciens
  ORGANISM  Streptomyces roseifaciens
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 441060)
  AUTHORS   Wu,C., Zhu,H., van Wezel,G.P. and Choi,Y.H.
  TITLE     Metabolomics-guided analysis of isocoumarin production by
            Streptomyces species MBT76 and biotransformation of flavonoids and
            phenylpropanoids
  JOURNAL   Metabolomics 12, 90 (2016)
   PUBMED   27073352
REFERENCE   2  (bases 1 to 441060)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     The complementarity of genome-mining and NMR metabolic-profiling
            facilitates lead-finding
  JOURNAL   Unpublished
REFERENCE   3  (bases 1 to 441060)
  AUTHORS   Wu,C., Du,C., Choi,Y.H. and Van Wezel,G.P.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-NOV-2015) Molecular Biotechnology, Institute of
            Biology Leiden, Sylviusweg 72, Leiden 2333BE, Netherlands
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Velvet v. 1.2.06
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 200.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001445655.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 03:28:28
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,528
            CDSs (total)                      :: 7,450
            Genes (coding)                    :: 7,245
            CDSs (with protein)               :: 7,245
            Genes (RNA)                       :: 78
            rRNAs                             :: 2, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 3, 2 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 205
            CDSs (without protein)            :: 205
            Pseudo Genes (ambiguous residues) :: 0 of 205
            Pseudo Genes (frameshifted)       :: 77 of 205
            Pseudo Genes (incomplete)         :: 168 of 205
            Pseudo Genes (internal stop)      :: 20 of 205
            Pseudo Genes (multiple problems)  :: 56 of 205
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:37:43
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 200257
            Orig. end                         :: 221325
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LNBE01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="4"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21068
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11068](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11068
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    288..303
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.71"
                     /tool="antismash"
     misc_feature    531..546
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            862..1689
                     /locus_tag="AS857_RS00820"
     CDS             862..1689
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014146434.1"
                     /locus_tag="AS857_RS00820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_058041130.1"
                     /transl_table=11
                     /translation="MSFMSPGSVVWFEIGTADIAAVRDFYGSVLGWTFETDQDSSTDGR
                     VYTRIMAPGAPWPMGAIEQGGSGGTGGEAVNLSVLSADVHDDVERLKRLGATVVVPPTT
                     VGEVTVFARLRDPLGNVFALFSRTTSEQLEERAAATEEHIEQAAYAPVPGGFAWFEIGT
                     TDPRATREFYEAAFGWRFEKDDSAGGKPYYNVFTGNEWPSGGMYDHSTGPGGADYTMPS
                     FMVTDVAATVAGAVAAGATVEHGPDGNPDGLAFARLIDLKGNRFGLFSMPRQP"
     gene            complement(1730..4027)
                     /locus_tag="AS857_RS00825"
     CDS             complement(1730..4027)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018541391.1"
                     /locus_tag="AS857_RS00825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="WP_058041131.1"
                     /transl_table=11
                     /translation="MSTKPRRDDHGIVITRAREHNLKDVCLTIPKGMITVFTGVSGSGK
                     SSVVFDTIAVESQRQLNETFPAFVRNRLPKYEKPEADGIGNLSPAIVVDQKPVGGGSRS
                     TVGTMTDIASLIRLLFSRAGTPSAGMSTAYSFNDPSGACPTCQGLGRTVQLDLDRFFDR
                     SKSLNTGALLFPLFNVGGVQWTLFTRSGLFDNDKPLRSYTKKEWQTLLHGSTDGEVKIE
                     LATRMGTQNVTYEGIVDRFNRLYLNRDLSTLSKRTRDAVEKFTTDAECPGCRGARLNAA
                     ALKTKVGGLSIADHMAMEITDLIRVLGEVDHPLGTPIARAAIEGLRRIDEIGLGYLHLG
                     RETGSLSGGEGQRLKIVRNLGSSLTGMTYIFDEPSTGLHPRDVHRVGKLLTRLRDQGNT
                     LLIVEHDRDVIALADHVVDMGPGAGTHGGHVVFEGSVAGLRRARTLTGRHLGRALPVKE
                     DVRTPTGHLPVTGASLHNLKNVSVDIPTGVLVAVTGVAGSGKSTLISEEFTARHPEAVF
                     IDQSAIGANSRSTPATWVGIMDTVRKLFADANGVPAGLFSFNSTGACPACGGKGTVTAD
                     MAFADPVTTVCESCRGLRYSAEALAHTLRGRTVTDVLALTAEEACAFFTGRGEKGVRAA
                     LETLVEVGLGYLTLGQPLSTLSGGERQRLKLAGHLGSRSSIYVLDEPTTGLHMADVETL
                     QRLLDRLVDDGNTVIVIEHNLDVVKRADRVIDMGPEGGRHGGQVLFTGTPAQLLEHRTS
                     HTARALRKDLAA"
     misc_feature    complement(4056..4071)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.42"
                     /tool="antismash"
     gene            complement(4126..5070)
                     /locus_tag="AS857_RS00830"
     CDS             complement(4126..5070)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016651 - oxidoreductase activity, acting
                     on NAD(P)H [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013567.4"
                     /locus_tag="AS857_RS00830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_058041132.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 4e-25, bitscore:
                     83.5, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIGLLGTGFAVAHAGVYAARPGTEVVVYGRSPEKLAMFARNFGF
                     ATTTEVDAIYDDPDVDLVDVCLPTALHKEHILRALAAGKHVLCELPIAPTVAEAEEITR
                     AAEASDKHVFIDMFMRVHPAVQHLHRVIRDGSLGELRALRSYRKAGPIWGPVDLGLGKL
                     ALEVMLSDLDYTVAALGLPREIHATGVTAGDGRAAAETVLRYDDAVVEYTASSMVPASY
                     GVTHGFEATFTEGVLELHERPFERTGPVMRLTEYTPAGSREVGLSPADNYTAAINHVLD
                     CVAKGTEDTLLTPRAATETLRLALDVDQALTRS"
     gene            5189..6196
                     /locus_tag="AS857_RS00835"
     CDS             5189..6196
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004002568.1"
                     /locus_tag="AS857_RS00835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="WYL domain-containing protein"
                     /protein_id="WP_058041133.1"
                     /transl_table=11
                     /translation="MTTDMPARMLRLLSLLQARREWAGTELADRLGVTTRTLRRDIDRL
                     RELGYPVEGTTGRAGGYRLAAGTAMPPLVLDDDEAIAVAVALRTATTDVTGIEETALRA
                     LAKLEQVLPARLRAQVTALQHATTAPVAYGGDARNRADPAVLALLAAACRDHEIVTFDY
                     ATRHGTPCPRRVEPHSLVPAAGRWYLVAYDTRKDDWRTYRLDRITDPAPTGHRVPPREL
                     PAPDPAAYVAAKIASAPARYRAVATVAAPADAVLARTQGLPERVTPIGTDTCTVDLSGD
                     SLHRIAQLLAALGGITTVEADPEVLAHLRDTARRTLRLTEGRGVPDTPPAGEQG"
     gene            complement(6723..7289)
                     /locus_tag="AS857_RS00840"
     CDS             complement(6723..7289)
                     /EC_number="3.5.4.33"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0052717 - tRNA-specific adenosine-34
                     deaminase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1240: riboflavin biosynthesis protein RibD"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151908.1"
                     /locus_tag="AS857_RS00840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nucleoside deaminase"
                     /protein_id="WP_058041313.1"
                     /transl_table=11
                     /translation="MEHKELITEAVRLATESVENGWGGPFGAVITRDGEIIARGQNRVL
                     LTGDPTAHAEVETIRKAVQYLNPEAPSIAEEHQNESTLEYVPRPEGSPDPVPERARMLQ
                     GCSIYISGAPCPMCMSAIYWSRIDAVYFSCALDDTRRIGFDDSFQYEDFGKPLDERRIK
                     IEQMHPEIGAHAYDAWTNKPNRHPY"
     misc_feature    complement(7343..7359)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.73"
                     /tool="antismash"
     gene            7447..8376
                     /locus_tag="AS857_RS00845"
     CDS             7447..8376
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012998198.1"
                     /locus_tag="AS857_RS00845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="WP_058041134.1"
                     /transl_table=11
                     /translation="MTSQKVRAGHADEYQRWQNRTNEAAREFDGFEGSEVYPPGAGSEN
                     EWVAVFRFSGIDYLTAWLESDRRQQLLAEGRRLFEEDPTQEVLRGGTTAEQTPETVTAV
                     ISHQVKPGREEGFLRWQEKVLKAQEKSPGFMGSELFKPVEGVEERWVAVFRFDSREHLE
                     EWLESDARSRLLEEGRAYFASYDVRKVGSAFSGWFRFGKGAQDAAPPNWKQAMSVILAL
                     YPTVMVLNLTVGYELDDLKVPGYIGLFIGNVLSVSILTWVLMPLVNKALGFWLAPSRAR
                     SLRVHVAGAAAVVLCYLLIIVVFGLTTH"
     gene            8421..9800
                     /locus_tag="AS857_RS00850"
     CDS             8421..9800
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018090776.1"
                     /locus_tag="AS857_RS00850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_058041135.1"
                     /transl_table=11
                     /translation="MSGRSPSARFEGTLIRRGDRAYDRARDAAVWNGLKPERFPEAIVQ
                     AASERDVPEALSYARSGGLRISTRSGGHNWSGSQLRDGSLLIDLSGLRRCSIDPGSATA
                     AVGPAATGEDLVKALAPYDLAFPVGHCPSVAVGGFLLSGGLGWNSRAWGPSCADVLEIQ
                     AVTADGRTVTCSETENPDLFWAARGAGPGFFAVVTRFRLRLHPHPGAVVTTSLTFPLAA
                     TGPVAAWAEQVARELPVNVETALVLTASGEPTTTAPPGPRILVGMTTFATTHEEALAAF
                     SPAGSCPFADSIVLRQEPEPTSFARLHQGTGAAWLSAHRYAADTLWSEESYETQLNRMA
                     DAVAHAPSGNSLVLAPVQPVSEEPALLRNMAFSPLGESYLVCYAIWNDPAADATNAQWL
                     RDAMASADPSGHGGHYIAETDLEADASRARRSYAPADWDRLQELKAAWDPENVFHSYLA
                     P"
     misc_feature    complement(9982..10000)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.31"
                     /tool="antismash"
     misc_feature    10000..10015
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.87"
                     /tool="antismash"
     gene            10001..11068
                     /locus_tag="AS857_RS00855"
     CDS             10001..11068
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642873.1"
                     /locus_tag="AS857_RS00855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_063804126.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.3e-63, bitscore:
                     209.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRILLHSAVSHGTSKRPPGSGEILERGTALVEPELRRIVARLHP
                     SVAKVCRYHMGWDAEGSEGLVQRAGKRVRAALAVLSVRSVGAPERFAAVAGTAVELVHQ
                     LSLLHDDVMDGDTERRGRPAAWAAFGTGPAVLAGDALVVQAVAGIFQAQAPGAAAATNA
                     LIVAVEKMVEGQAEDLSLEGWSVSEVSPDQYVRMARGKTGALFGCAAALGAVLADAPAP
                     VTQALHSAGSELGVAFQILDDILGLWGESTITGKPVGTDLMRGKKTLPLLLAVGSGTAA
                     GQRLAALLDSGPPAPADVPEAMRLLEETESRRRAEEMAVRHVASATAALGEAAIPADVR
                     EQWRHFITDLSRRSS"
     gene            11134..11769
                     /locus_tag="AS857_RS00860"
     CDS             11134..11769
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642874.1"
                     /locus_tag="AS857_RS00860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_058041315.1"
                     /transl_table=11
                     /translation="MRVHDVHKSYRSRRVLRGVSFSLEPGTLAGVVGENGSGKSTLLRI
                     LCGQIAADSGEVEHGGSLGYCPQETVLNDSLTVDQHLSWFRTAYDLEGLGRAGELLEEL
                     GFAEYRHTRVDALSGGTRQKLNLTLALMHDPDVLLLDEPYQGFDWETYLRFWDVAARLR
                     ERGRCVLVVSHLAWDTERLDIVLRLRHGVAAPGESDVKRAVTTRGADR"
     gene            11766..12566
                     /locus_tag="AS857_RS00865"
     CDS             11766..12566
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569179.1"
                     /locus_tag="AS857_RS00865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_058041136.1"
                     /transl_table=11
                     /translation="MTWTRRGLRTGASFALLEHARNHLALVLIVVYIPLWLTLEHLFVT
                     PAPARFLLRATGRTVTVNGNHLTMVSGAVNTVTLIVGFMMFITTFKSLAFDRRLAFAGY
                     PRTFLLLSKVIAMTVASALIAGYTTAVICWYWDPVRPGLLALGLFTAAVAYGGIGVLLG
                     AFLRNELAALFVIIMASLLDTMLQNPMSNTGADKDGLQLLPGYGPTQVSVAAGFTSTDT
                     PYGHLLLGPLWFLLMWGLGTAAFFARTRNHLRVPRSTQPTRRPT"
     gene            12563..13009
                     /locus_tag="AS857_RS00870"
     CDS             12563..13009
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AS857_RS00870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="SRPBCC family protein"
                     /protein_id="WP_079109959.1"
                     /transl_table=11
                     /translation="MSRHEMHFAGLWRAPLPPGVMYAKLADIEHYPEWWPAFRSVKQTG
                     ERECEIVIRSIMPYELTVRLTPLVQDPVERVLDAALEGGIAGNVRWHVGDDGGHGCVAS
                     FTERVSVRKAALRRWMPLARPFFHLNHAVAMRSGQRGARLNRSA"
     gene            complement(13030..13683)
                     /locus_tag="AS857_RS00875"
     CDS             complement(13030..13683)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891835.1"
                     /locus_tag="AS857_RS00875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_058041137.1"
                     /transl_table=11
                     /translation="MATTDASGPRERYRTQVRAEIKKYAWEQIATAGASALSLNAIAKQ
                     MGMSGPALYRYFAGRDELITELVREAYRSLAETLRTASATGAGLAALAHALRAWALEDP
                     QRYLLVYGTPVPGYRAPEDITGIADEIMKTLLDACTALAPDGPATPFTAHLEDHREWAD
                     GHPAPPAALHRALAVWTRLHGVLSLELAGHFTNMGFDPALFFTAELDDLLAHPA"
     misc_feature    13834..13852
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.67"
                     /tool="antismash"
     gene            13839..14483
                     /locus_tag="AS857_RS00880"
     CDS             13839..14483
                     /NRPS_PKS="Domain: Polyketide_cyc2 (57-206). E-value:
                     4.2e-17. Score: 54.8. Matches aSDomain:
                     nrpspksdomains_AS857_RS00880_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891834.1"
                     /locus_tag="AS857_RS00880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SRPBCC family protein"
                     /protein_id="WP_058041138.1"
                     /transl_table=11
                     /translation="MSGIRSTRVRAALFTVPLVAIGLLGIAAAPAGAAATATHPVKSLT
                     CRGEGVDPDALVRSRTETVIHAPLRTIWKLQTDVERWPSWQGGITAMKRLDHGPFRKGS
                     AFRWTTPVPPNPTTPATSLEITSTVEQLKRDSCIRWTGPAVAEGLRIDGVHVWNFTRVK
                     GGVRVSTEETHTGAEVEADVPAATEILHQGLEAWLRDLKTTAEATTHNRPH"
     aSDomain        14010..14456
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AS857_RS00880_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="4.20E-17"
                     /label="AS857_RS00880_Polyketide_cyc2.1"
                     /locus_tag="AS857_RS00880"
                     /protein_end="206"
                     /protein_start="57"
                     /score="54.8"
                     /tool="antismash"
                     /translation="RSRTETVIHAPLRTIWKLQTDVERWPSWQGGITAMKRLDHGPFRK
                     GSAFRWTTPVPPNPTTPATSLEITSTVEQLKRDSCIRWTGPAVAEGLRIDGVHVWNFTR
                     VKGGVRVSTEETHTGAEVEADVPAATEILHQGLEAWLRDLKTTAE"
     gene            complement(14566..15159)
                     /locus_tag="AS857_RS00885"
     CDS             complement(14566..15159)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127107.1"
                     /locus_tag="AS857_RS00885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_058041139.1"
                     /transl_table=11
                     /translation="MTDAPLGRSAVYTILTTGYVGSTGPGVAATVSYVSDAGRHVIFDP
                     GMVAHRDHILGPLAELGLGPDDITDVVLSHHHPDNTMNVGLFGRARVHDHKVEYRGDQW
                     KNRDAEGYELTPSLRLIRTPGHSPEDITLLAGTDSGVVAFAGDLWWHSEGPADDPVAPD
                     REVLRASRLRVLAAADLIVPGHGGPFEADDTVPR"
     gene            15290..16198
                     /locus_tag="AS857_RS00890"
     CDS             15290..16198
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982097.1"
                     /locus_tag="AS857_RS00890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_058041140.1"
                     /transl_table=11
                     /translation="MLAVGIVTEVFAPRGEGLPGFDFALCTDRPGPVPTDVGVPIAIEH
                     GLDRLAAADLVIALPWADFRTPPGPAVLDALSAAHERGSLVAAHCVGAFALAAAGLLDG
                     RRATTHWRFAELLARRHPAVTVEPDALYIDEGRITTGAGAAAGFDLCLHLLRREYGAAM
                     ANAIARDMVLPAHRDGGQAQYLAAPVPENCQDERLAEVLAWAREHLHEPLPVAELARRA
                     VMSKRSFARRFAAATGTTPHAWLRGLRLSSAEELLETTDLPVEEIARRVGYGSAAVLRE
                     QFVRRRGVPPRSYRRSFTSAP"
     gene            complement(16236..16937)
                     /locus_tag="AS857_RS00895"
     CDS             complement(16236..16937)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059223.1"
                     /locus_tag="AS857_RS00895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="WP_058041317.1"
                     /transl_table=11
                     /translation="MKTIGLIGGMSWESTAEYYRILNERTRERLGGLHSARCVLHSVDF
                     AEIEQLQVQGRWAEAGEVLADAARSLEAAGADLLLICTNTMHKVADSVEAATSVPLLHL
                     ADATAAAVRAAGLRRVGLLGTAFTMEQDFYRGRLAAGGLDVCVPDSEGRALVHRVIYEE
                     LCMGVVRDESRAAYRKVVEELVDAGAEGVILGCTEIELLIGADDSPVPLFPTARLHAEA
                     AVDAALTAHVD"
     gene            complement(17103..18020)
                     /locus_tag="AS857_RS00900"
     CDS             complement(17103..18020)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014734.4"
                     /locus_tag="AS857_RS00900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="galactosyltransferase-related protein"
                     /protein_id="WP_058041141.1"
                     /transl_table=11
                     /translation="MPEVTIAIPLYGDHRGRACLATVAGAWLAQDVPCEVVIATAGDLA
                     GDLAAVLPGVRVIRADPGIRSAGVLRNIAAAAARSPLLCLTDADVLPLGRDYLRRCLDL
                     AGDAALAQPWMYRLPGGVEALARTGTVLAEAVGMRVTATVGRSCYVRAAPGPALVPDTG
                     ERLEWEVLGVGALQVPTPMVWPPRAAYDPGLPKYMQRQAPFHWGQLLLPADRFAEIGGY
                     CAAYAGWGCEDDDLLVKLVSRAPLIRLWHTGASLACLHLEHPRHYVAGPERPANEDRLR
                     QRLAAGPAAMIEEDLRSGGRFRTP"
     gene            complement(18008..19999)
                     /locus_tag="AS857_RS00905"
     CDS             complement(18008..19999)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF021616.4"
                     /locus_tag="AS857_RS00905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase"
                     /protein_id="WP_160330161.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 7.6e-18,
                     bitscore: 59.3, seeds: 63, tool: rule-based-clusters)"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.3e-26,
                     bitscore: 87.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPSLRVALVVRDFSPSWDQVSRYVLNAGRQLVREGHSVRLLAAT
                     GDFATAGRHGLQAVPLPAPDESHTYLTPAHAHADRVYRALRTLATTGPGLDAVEFADRD
                     GEGLTTIRAKRLLGEFPDTALTVRLHAPAALTAPFSGEQPGDTDRAMAAYAEDYCLRHA
                     DLLLLPSRRVAGYARALNSRCRYSPCPIPQADLQVTSAGPRQVTFAGPLSPLGGADVFL
                     AAAARLARADPHVTFTLFGPRSAHRRLGLPYDQHLARLVTGPLRGRVSFLDPAEVPDRA
                     HLWRNSRLCVVPARWDNCPYEALEAMSHGCPVVCTSGGGTAEVVTDQGAGFITPADDPG
                     ALARLLGRLTGDDHRLLGEAARRAPAAARAYGDPVDAARRLVGHYREARRPPRTGSAGG
                     MLPTVSVVIAVYNKGRWLPDTLASVRAQTHPRVEVVVVNDGSTDPATRAAFDALTGVVK
                     VDKPNGGPGSAYNAGVAAARGEFILPLDGDDLLQPDCVATAVAALRRAPDLGHVTCYVR
                     HFDLVDTVDAPLGTVPGLMPFLNTGGKRTRLLRRSALTAIGGYDERLPTLDDVELLIRL
                     ERAGHPGDVIPRVLFSYRRHAASLTFASPGELFLEEHQYILAKHADLVAAQGPAACHHL
                     LHLWKNRIEISHSARRRRTLQEGPSCPK"
ORIGIN
        1 ctcagtctga gcgtgttctt cctcgcctgg atgatctacc ttcagatcgg cctcggctac
       61 agcgccctgc gcgctggcct ggccggactg ccgttctccg tcgccgtcat ggccggcgcc
      121 gggctggcga tgggcgcact ggtgcccagg ttcggccgca tcgttctcca ggccggcgcc
      181 ttgctgatgg tcgcgggact gctgctgttc tcatggcagg tcggcgcggc gggaccggcg
      241 atcggttact ggcagatggc ctggcccatg gtggtcctcg gactcggcat gggaatgatc
      301 gtcgccccgc tcaccgacac cgtcctgacc gacgtccccg tccgtgacgc gggctccgcc
      361 tccggtgtca gcgccacggc cggccagctc ggcagcgcct tcggcgcggc cctggtcgcg
      421 gtcgtcttct tcggactgct cagcagccac acggcgaacg acgacgtcac cgccaggctc
      481 cgcaccgacc tggccaccac gtcgctcggc accgagcagg ccgaccgtgc ggtgaccgca
      541 ttcacgatgt gccaccgcga acgcgccgcc caggccgacc ccggccgcac cccgggcagc
      601 tgcaccgccc tggcgcctgc gcacggcgac ccgcgtgccg cggacgccct gcgacgggcc
      661 ggacagcagg ccaacgcgcg gacctacacc gacacgatcg gcgagagcgt cctgtacgtc
      721 acgggactga tcgccgcagc tctcctgctg atgttcgccc tgccccggaa ggtccgtacg
      781 ccggaccccg cggcggacca gcaggacacc acccccacaa ccgctgtcaa cacggcctga
      841 acgcaggaag agagccttct catgagcttc atgtcccccg gatccgtagt ctggttcgag
      901 atcggcaccg ccgacatcgc cgccgtgcgg gacttctacg gaagcgtgct cggctggacc
      961 ttcgagaccg accaggactc ctccaccgac ggacgcgtct acacccgcat catggccccg
     1021 ggcgccccgt ggcccatggg cgcgatcgag cagggcggga gcggcggcac cggtggcgag
     1081 gccgtcaacc tctccgtgct gtccgcggac gtccacgatg acgtcgagcg cctgaagagg
     1141 ctcggcgcga ccgtcgtcgt cccgcccacc acggtcggcg aggtcaccgt cttcgcccgg
     1201 ctccgcgacc cgctcggcaa cgtcttcgcc ctcttctccc gcacgacctc ggagcagctg
     1261 gaagagcggg cggccgcgac ggaggagcac atcgagcagg ccgcctacgc gcccgtcccg
     1321 ggcggcttcg cctggttcga gatcggcacc accgacccgc gggccacccg cgagttctac
     1381 gaggccgcgt tcggctggcg gttcgagaag gacgacagtg cgggcggcaa gccgtactac
     1441 aacgtcttca ccggaaacga gtggccctcg ggcggcatgt acgaccacag caccggcccg
     1501 ggcggcgccg actacaccat gccctcgttc atggtcaccg atgtggccgc gacggtcgcc
     1561 ggggccgtcg ctgcgggggc gacggtcgag cacggtccgg acggcaaccc ggacgggctg
     1621 gccttcgccc gcctgatcga cctgaagggc aaccgcttcg gcctgttctc gatgccccgg
     1681 cagccctgac gcatgaggaa ggggcccggc gcgccggcgc cgggccctgt catgcagcca
     1741 ggtccttccg cagggctcgt gcggtgtggg aggtgcggtg ctcgagcaac tgggcggggg
     1801 ttccggtgaa caggacctgc ccgccgtggc ggccgccctc cgggcccatg tcgatgaccc
     1861 ggtcggcgcg cttgacgaca tcgaggttgt gctcgatgac gatgaccgtg ttgccgtcgt
     1921 cgaccagccg gtccagcagc cgctggaggg tttccacgtc cgccatgtgc aggccggtgg
     1981 tgggctcgtc cagcacgtag atgctgctgc ggctgccgag gtgcccggcg agcttcaggc
     2041 gctggcgttc gcccccggac agggtcgaca agggctgccc cagtgtgagg tagccgagcc
     2101 cgacctccac gagcgtctcc agcgccgccc gcacgccctt ctctccccgt ccggtgaaga
     2161 acgcgcatgc ctcctcggcg gtcagggcga ggacatcggt gaccgtcctg ccgcgcaggg
     2221 tgtgcgcgag cgcctcggcg ctgtagcgaa ggccgcggca ggactcgcac accgtggtga
     2281 ccgggtcggc gaaggccatg tccgcggtga cggtgccctt tccgccgcag gccgggcagg
     2341 cgccggtgga gttgaagctg aacaggcccg ccggaacgcc gttggcgtcg gcgaagagct
     2401 tgcgcacggt gtccatgatc ccgacccagg ttgccggggt ggagcgggag ttcgcgccga
     2461 tcgcgctctg gtcgatgaag accgcctcgg gatgccgggc ggtgaactcc tccgatatga
     2521 gcgtggactt gccggacccg gccacgccgg tgaccgcgac caggacaccg gtggggatgt
     2581 ccacggacac gttcttgagg ttgtgcaggc tcgcccccgt gaccggcagg tgcccggtgg
     2641 gggtgcggac gtcctccttc accggcagcg cacggcccaa gtggcggccc gtgagggttc
     2701 gtgcccggcg caggccggcg acgctgccct cgaagacgac gtgaccgcca tgggtgccgg
     2761 cgccggggcc catgtcgacg acgtggtcgg ccagcgcgat gacgtcccgg tcgtgctcga
     2821 cgatcagcag cgtgttgccc tggtcccgca gccgggtcag cagcttgccc acgcggtgga
     2881 cgtcgcgcgg gtgcaggccg gtggagggct cgtcgaagat gtaggtcatg ccggtgaggc
     2941 tggagcccag gttgcgcacg atcttcagcc gctgcccctc gccgccggag agcgaaccgg
     3001 tctcccggcc caggtgcaga tagcccagcc cgatctcgtc gatgcgccgc agaccttcga
     3061 tcgccgccct cgcgatcggc gtacccagag gatggtcgac ctcgcccagg acgcggatca
     3121 ggtcggtgat ctccatggcc atgtggtcgg cgatggacag cccgcccacc ttcgtcttca
     3181 gggcggccgc attgagccgt gcgccccggc agccggggca ctcggcgtcg gtggtgaact
     3241 tctccaccgc gtcccgtgtc cgcttcgaga gtgtggaaag gtcccggttg aggtagagcc
     3301 ggttgaagcg gtcgacgatg ccctcgtagg tgacgttctg ggtccccatc cgggtcgcaa
     3361 gctcgatctt cacctcgccg tcggtgctgc cgtgcagcag cgtttgccac tccttcttcg
     3421 tgtacgagcg cagcggcttg tcgttgtcga acagtccgga gcgggtgaac agcgtccact
     3481 gcacgccccc gacattgaac agagggaaga gcagggcccc ggtgttcagg gacttgctcc
     3541 ggtcgaagaa gcggtccagg tcgagctgga cggtacggcc gagcccttgg caggtggggc
     3601 aggccccgga ggggtcgttg aaggagtacg cggtggacat gcccgcggac ggcgtgcccg
     3661 cgcgggagaa cagcagccgt atgagcgagg cgatgtccgt catcgtgccg accgtcgagc
     3721 ggctcccgcc gccgaccggc ttctggtcca ccacgatcgc gggagaaagg ttgccgatgc
     3781 cgtcggcctc gggcttctcg tatttcggca ggcggttgcg gacgaaggcc gggaaggtct
     3841 cgttgagctg ccgctgggac tcgacggcga tcgtgtcgaa gaccaccgag gactttccgg
     3901 atccggacac ccccgtgaac accgtgatca tccccttggg gatggtcagg cagacgtcct
     3961 tgaggttgtg ctcgcgggca cgggtgatga cgatgccgtg atcgtcacga cggggcttgg
     4021 tgctcatgcg gtgctcctgg caggtggtgc gggcccggac caggcggtga cggtctgggc
     4081 ggccccggtc cgggaggggg cggggacagg actgaagggg tggggtcagg accgggtgag
     4141 ggcctggtcg acgtcgagcg ccagtcgcag cgtctcggtg gccgcgcgtg gggtgaggag
     4201 ggtgtcctcg gtgcccttgg cgacgcagtc cagaacgtgg ttgatcgcgg cggtgtagtt
     4261 gtcggcgggg gagaggccga cctcgcggga gccggccggg gtgtactcgg tcaggcgcat
     4321 gaccgggccg gtgcgctcga agggacgctc gtgcagttcg aggacccctt cggtgaacgt
     4381 ggcctcgaag ccgtgggtga cgccgtacga ggccgggacc atcgacgagg cggtgtactc
     4441 cacgaccgcg tcgtcgtagc gcagcacggt ctcggcagcg gcccgcccgt cgccggcggt
     4501 gaccccggtg gcgtggattt cccgcggcag gccgagggcg gcgacggtgt agtccaggtc
     4561 ggagagcatc acctccagcg cgagcttgcc caggcccagg tcgaccgggc cccagatcgg
     4621 gccggccttg cggtacgagc gcagggcgcg cagctcaccg agggagccgt cccggatcac
     4681 ccggtgcagg tgctgcacgg ccgggtgcac ccgcatgaac atgtcgatga acacgtgctt
     4741 gtcgctcgct tcggcggcgc gggtgatctc ctcggcctcg gcgacggtgg gggcgatggg
     4801 cagctcgcac agcacgtgct tgccggccgc cagcgcccgc aggatgtgct ccttgtgcag
     4861 ggccgtcggc aggcagacgt ccaccaggtc gacgtccggg tcgtcgtaga tcgcgtccac
     4921 ctccgtggtc gtggcgaagc cgaagttccg ggcgaacatc gcgagcttct cggggctgcg
     4981 tccgtagacg accacctcgg tgccggggcg ggcggcgtag acgccggcgt gggcgacggc
     5041 gaatccggtt cccagcagtc cgatcttcat ggcgacacat ctcctcagcg atatgcgagg
     5101 gaatcatctg gttcgttccc tccggcaaat cccacgctag gagcctttta ggacatgact
     5161 cgtccgcatg tggagtcaca gtggaggcat gacgaccgac atgcccgccc ggatgctccg
     5221 gctgctctcg ctcctccagg cccgccgcga atgggccggt acggagctcg ccgaccggct
     5281 cggcgtcacc acccgcaccc tgcgccgcga catcgaccgc ctgcgcgagc tcggctatcc
     5341 cgtcgagggc accaccggcc gcgcaggcgg ataccgcctc gccgccggca ccgccatgcc
     5401 gccactggtc ctggacgacg acgaggccat cgccgttgcc gtcgccctgc gcaccgccac
     5461 cacggacgtc accggcatcg aggaaaccgc cctacgcgcc ctcgccaaac tcgaacaggt
     5521 cctccccgcc cgcctgcgcg cccaggtcac cgcactccag cacgccacca ccgcacccgt
     5581 cgcctacgga ggcgatgcac gcaaccgggc cgacccggcg gtgctggccc tgctggccgc
     5641 ggcctgccgc gaccacgaga tcgtcacctt cgactacgcc acccgccacg gcaccccctg
     5701 cccccgccgc gtcgaacccc acagtctcgt ccccgcggcc ggtcgctggt acctcgtcgc
     5761 ctacgacacc cgcaaagacg actggcgcac ctaccgcctc gaccgcatca ccgaccctgc
     5821 ccccaccggc caccgcgtcc cgccccgcga actgcccgca cccgaccccg ccgcctacgt
     5881 ggccgcgaag atcgcctctg cgcccgcccg ctaccgcgcc gtcgccacgg tcgcggcccc
     5941 cgcggacgcc gtcctcgccc gcacccaggg cctgcccgag cgcgtcacgc ccatcggtac
     6001 cgacacctgc acggtcgacc tctccggtga ctccctccac cgcatcgccc aactcctcgc
     6061 ggcactcggc gggatcacca ctgtcgaggc cgacccggaa gtcctcgccc acttgcgcga
     6121 cacggcgcga cgcactctac ggctcacgga gggcagaggc gtgcccgata cgcctccggc
     6181 cggagaacag gggtgagtaa agaaagaagc ggggcgcggg gctccgaggg ctcggctgcc
     6241 tcggagcccc cgaatctgtc agcggcgctt cttggtcctc ttctgctgcg gcgggttcca
     6301 ctcgcctcgg tgaatctggc agcgggagta cccgatcatc gcaggcttct tgcacggctt
     6361 gcccgacttc gttcgagtcg aaccgcactt gacctgtttc cccatgcacc ctccccaccc
     6421 ggctggtgat gcgtcaggtg aatcgtcgcc gacggggggt gcatgccgcg ctcgatgctg
     6481 ccgctcgcgg ctcgttccag tccattcaag gccgaatatc cgctttcctt caccagcgct
     6541 gcgcccttgc gtcacgcatg cctgccttgc cacaggtgat tgcgtgacca acgctggtgt
     6601 catcaggtgc caacgcccga ctgaaatacc gctgatcgac atttcggagt cggccggcgt
     6661 gaccgactcg tacatgaccg gatcgcactg aggagactat gacgtcgggg cggagcatcc
     6721 gctcaatacg ggtgccggtt cggcttgttc gtccatgcgt cgtaggcgtg cgcgccgatt
     6781 tcgggatgca tttgctcgat cttgattctc cgctcgtcga gcggcttccc gaagtcctcg
     6841 tactggaacg aatcgtcgaa accgatgcgc cgggtgtcgt ccaaggcgca gctgaagtag
     6901 acggcgtcga tccgggacca gtagatggcg ctcatgcaca tcgggcacgg agcgccgctg
     6961 atgtagatgg agcagccttg gagcatgcgg gcccgctcgg gtacggggtc cggtgagcct
     7021 tcagggcggg ggacgtattc cagcgtgctc tcgttctgat gctcttcggc gatcgacggc
     7081 gcctcggggt tgaggtattg cacggccttg cggatggttt cgacttcggc gtgggccgtg
     7141 gggtctccgg tcagcaggac ccggttctgt ccgcgggcga tgatctcccc gtctcgggtg
     7201 atcactgcgc cgaaggggcc gccccagccg ttctccacgg actcggtggc gaggcgcacc
     7261 gcttcggtga tgagctcttt gtgttccatc gcggagtctc ccatcggcgt cggtttcccg
     7321 ctgcggaggg ggctcgcgga gcaggtaata aaacgcccgg tttgccctgt aaatacccta
     7381 tcgactaggc tactccaggt gagtccacgt gcaagccgtg actccacggc cgagaatgcc
     7441 accgttgtga cctcgcagaa agtgcgcgca ggccacgccg acgagtacca gcgctggcag
     7501 aaccggacga acgaggcggc ccgcgaattc gacgggttcg agggatccga ggtgtacccg
     7561 cccggcgcgg gctccgaaaa cgaatgggta gcagtattcc gattctccgg gatcgactac
     7621 ctcaccgcct ggctggaatc ggaccgccgg cagcaactgc tcgccgaagg ccggagactc
     7681 ttcgaagagg acccgacaca agaggtgctc cgcggcggca ccacggccga acagaccccc
     7741 gagaccgtca cggccgtcat ctcccaccag gtgaagcccg ggcgcgagga gggcttcctg
     7801 cggtggcagg agaaggtcct caaagcgcag gagaagtccc ccggattcat ggggtccgag
     7861 ttgttcaaac cggtcgaggg ggtcgaggaa cgctgggtcg ccgtcttccg gttcgactcc
     7921 cgcgagcacc tcgaggaatg gctcgagtcc gatgcccgca gcaggctgct cgaagagggg
     7981 cgcgcctact tcgcctccta cgacgtacgc aaggtcgggt ccgcattcag cggctggttc
     8041 cgcttcggca agggcgcgca ggacgctgct ccgcccaact ggaagcaggc catgtccgtg
     8101 atcctcgcgc tctatcccac ggtcatggtg ctgaacctga ccgtgggata cgagctggac
     8161 gatctcaagg tgcccggata cataggcctg ttcatcggca acgtactgag cgtcagcata
     8221 ctgacctggg tactgatgcc tctggtgaac aaggctctgg gcttctggct cgcacccagc
     8281 cgcgcgcgca gcctccgcgt ccacgtggcg ggtgctgcgg cagtggtgct ctgttatctc
     8341 ctgatcatcg tggtcttcgg cctgacaacc cactgaccga ccccaccgcc ggccgcaaca
     8401 ggcccatcga ggaggcgagg atgtccgggc gctcaccctc agcacgcttc gaaggaaccc
     8461 tgatccggcg gggcgaccgc gcgtacgaca gagccaggga cgccgcggtg tggaacgggc
     8521 tcaaaccgga gcgcttcccc gaggccatcg tgcaggcggc gtccgagcgg gacgttccgg
     8581 aggccctttc ctacgcacgc tccgggggct tgcgcatctc gacgcgttcc ggtggacaca
     8641 actggtccgg ctcccagctc cgcgacggga gcctgctgat cgacctctcc gggctccggc
     8701 ggtgcagcat cgacccggga tcggcgacgg ccgctgtggg gcccgccgcc accggggagg
     8761 atctggtcaa ggcgctggct ccgtacgacc tcgcctttcc cgtgggccac tgcccttccg
     8821 tcgcggtggg cggattcctg ctcagcggcg gactcggttg gaactctcgc gcctggggac
     8881 cgtcatgcgc cgacgtcctg gagatccagg ccgtcaccgc cgacggccgg acggtcacct
     8941 gcagcgagac cgagaacccc gacctcttct gggccgcccg cggcgcgggg cccggcttct
     9001 tcgccgtcgt cacccgcttc cggctccgct tgcaccccca cccgggggcc gtcgtgacca
     9061 ccagcctcac cttcccactg gccgcaaccg gtcccgtggc ggcctgggcg gaacaggtcg
     9121 cacgcgaact cccggtgaac gtcgagacgg ctctcgtcct cacggcttcc ggtgaaccga
     9181 ccaccacagc accgcccggt ccgcggatcc tggtcggcat gaccacattc gccacgacgc
     9241 acgaggaagc acttgccgct ttctcgcccg ccgggtcctg ccccttcgcc gacagcatcg
     9301 tcctccggca ggagcccgag ccgacgtcgt tcgcccgcct gcaccagggc accggtgcgg
     9361 catggctttc ggcgcaccgg tacgcggccg acacgctgtg gtcggaggag tcgtacgaga
     9421 cgcaactgaa ccgtatggcc gacgcggtgg cccacgcgcc ctccggtaat tctctcgtgc
     9481 tcgcgccggt gcagcccgta tccgaagagc ccgccctgct acggaacatg gccttctcgc
     9541 cgctcggcga gtcctacctc gtgtgctacg cgatctggaa cgatcccgct gcggacgcga
     9601 ccaacgcgca gtggctgcgg gacgccatgg cttcggccga tccgtcgggg cacggcgggc
     9661 actacatcgc cgagacggac ctggaagccg acgcctcccg ggcccggcgc tcgtacgcac
     9721 ccgccgactg ggaccgcctg caggagctca aagccgcatg ggacccggag aacgtcttcc
     9781 actcctacct ggcaccgtga gccgagggcc ccggcggacg cctcggatgt ctcggacgta
     9841 tcgaggtggt ctttgccggc agcgagcacg ggcagccggc tgctgaatcc ggccggaccg
     9901 cgactgccgc cgtaactccc cgatcgtccg gttcgttatg cgatgggcga aggccggaga
     9961 tgaccactcg ggctgcagac cactggggga cgagacagta atgacacgca ttctgttgca
    10021 cagcgctgtc tcgcacggca cgtcgaagcg gccgccggga agtggggaga tcctggagcg
    10081 ggggacggcg ctcgtcgagc ccgagctgcg ccggatcgtg gcacggcttc atccgtccgt
    10141 ggccaaggtg tgccgctacc acatggggtg ggacgcagag ggctccgagg gcctcgtgca
    10201 gcgagccggc aagcgtgtgc gcgcggcgct ggcggtgctg tcggtccgct ccgtcggagc
    10261 gccggagcgg ttcgccgccg tagccggaac ggccgtcgag ctcgtgcacc agctctccct
    10321 gctgcacgac gatgtcatgg acggtgacac cgagcggcgc ggtcggcccg ctgcctgggc
    10381 cgcgttcggt acgggcccgg ccgtgctcgc cggtgacgcc ctcgtcgtgc aggcggtagc
    10441 agggatcttc caggcgcagg ctcccggggc tgctgcggcc accaacgctc tcatcgtggc
    10501 cgtggagaag atggtggagg ggcaggcgga ggacctttcg ctcgaagggt ggtccgtgag
    10561 cgaggtctcg ccggaccagt acgtgcgcat ggcacgcggc aagaccggcg ccctcttcgg
    10621 ctgtgccgcg gccttgggcg ccgtgctggc cgacgcgccg gctcccgtga cgcaggcact
    10681 ccactccgcg gggagcgagt tgggggtggc cttccagatc ctcgacgaca tcctcggcct
    10741 gtggggtgag agcacgatca ccgggaagcc cgtcgggacg gatctgatgc gcggcaagaa
    10801 gacgttgccc ctgctgcttg cggtcggctc cggcaccgcc gccggtcagc ggctcgcggc
    10861 cctgctggac tccggtccgc cggctccggc tgacgtcccc gaagccatgc ggctgctgga
    10921 ggagacagag agcagacgac gtgccgagga gatggctgtc cgtcacgtgg cctcggcaac
    10981 cgccgccctc ggcgaggcgg caatccctgc cgacgtgcgg gaacagtggc ggcatttcat
    11041 caccgacctg tcccgccgta gcagctgaca gtcaccacga cgacgatcgt tacgcaggag
    11101 gaagcactcg ccgtgccccg aaccccgcat gctctgcgcg tgcacgacgt acacaagtcc
    11161 taccggtcgc gccgcgtgct ccgaggcgtc tcgttcagcc tggagccggg cacactggca
    11221 ggcgtcgtgg gtgagaacgg ctccgggaag agcacgctgc tgcgcatcct gtgcggccag
    11281 atcgctgccg actccggcga ggtcgagcac ggtggctccc tggggtactg cccgcaggag
    11341 accgtgctca acgactccct cacggtcgac cagcacctga gctggttccg gaccgcctac
    11401 gacctggagg ggctcggccg ggccggggaa ctgctcgaag aactcggttt cgccgaatac
    11461 cggcacaccc gtgtggacgc cctcagcgga ggtacccggc agaagctcaa tctcaccctg
    11521 gcgctcatgc acgacccgga cgtgctgttg ctggacgagc cgtaccaggg cttcgactgg
    11581 gagacgtacc tccgcttctg ggacgtcgcg gcccggctcc gcgagcgggg gcgctgcgtc
    11641 ctcgtcgtgt cgcacctggc ctgggacacc gagcggctcg acatcgtgct ccgtctgcgt
    11701 cacggagtgg cagcaccggg ggagtccgac gtgaagcgcg cggtgacgac gcgaggggcg
    11761 gaccgttgac ctggactcgg agagggctcc gcacgggcgc ctcgttcgct ctcctggaac
    11821 acgctcgcaa ccatctcgcc ctggtgctga tcgtcgtgta catccccctc tggctgacgc
    11881 tggagcactt gttcgtcacc ccggcgccgg cgcggttcct gctgcgcgcg acggggcgta
    11941 ccgtcaccgt caacggaaat catctgacga tggtgtccgg ggccgtcaac acggtgacgc
    12001 tcatcgtcgg cttcatgatg ttcatcacga ccttcaagtc cctcgccttc gaccgcaggc
    12061 tcgcgttcgc cggctacccc cggacctttc tgctcctgag caaggtcatt gccatgaccg
    12121 tcgcctccgc cctcatcgcg ggttacacca cggccgtcat ctgctggtac tgggatcccg
    12181 tccggccggg gctcctcgcg ctcggtctgt tcaccgccgc ggtcgcttac ggcggtatcg
    12241 gcgtcctcct cggcgccttt ctgcgcaacg agctggcggc gctgttcgtc atcatcatgg
    12301 cgagcctgct cgacaccatg ctgcagaacc ccatgagcaa tacgggagcc gacaaggacg
    12361 ggctccaact gctccccggc tacggtccga cacaggtcag cgttgcagca ggtttcacct
    12421 ccacggacac cccgtacgga cacctcctgc tcggcccgct gtggttcctg ctcatgtggg
    12481 gactcggaac cgccgccttc ttcgctcgca cccgcaacca cctccgagtg ccccggagca
    12541 cacagccgac aaggagaccg acgtgagccg ccacgagatg cacttcgccg gactctggag
    12601 ggcaccgctc ccgcccggcg tcatgtacgc gaagcttgcc gacatcgagc actaccccga
    12661 gtggtggccg gccttccgtt ccgtgaagca gaccggcgaa cgggagtgcg agatcgtcat
    12721 caggtcgatc atgccctacg agctgacggt acggctgaca cctctcgtcc aggatccggt
    12781 cgagcgtgtc ctggacgcgg cactcgaagg gggcatcgcg ggcaacgtgc gatggcacgt
    12841 gggagacgac ggcgggcacg gctgcgtggc ctccttcacc gagcgcgtca gcgtcaggaa
    12901 ggccgcgttg cggcgctgga tgccactggc acgcccgttc ttccacctca accacgccgt
    12961 ggccatgcga tcgggacagc gcggtgccag gctgaacagg tccgcgtagg cgttgcaccg
    13021 cgtgcgttgt caggctgggt gtgccaggag gtcgtccagt tcggctgtga agaacagggc
    13081 ggggtcgaag cccatgttgg tgaagtggcc ggcgagttcc agggacagga cgccgtgcag
    13141 gcgggtccag acggcgaggg cccggtggag ggccgcgggc ggggcggggt gtccgtcggc
    13201 ccactcgcgg tggtcttcca ggtgggcggt gaacggagtc gcggggccgt ccggggcgag
    13261 cgccgtgcac gcgtcgagca gggttttcat gatctcgtcg gcgatgcccg tgatgtcctc
    13321 gggtgcccgg tagccgggga cgggggtgcc gtagacgagg aggtaccgct gggggtcctc
    13381 cagggcccag gctcgtaggg cgtgggccag tgcggcgagg ccggcaccgg tggcggaggc
    13441 cgtgcggagg gtctcggcga ggcttcggta cgcctcccgg acgagttcgg tgatcagctc
    13501 gtcgcggccg gcgaagtacc ggtagagcgc gggcccgctc atgcccatct gtttggcgat
    13561 cgcgttgagg gagagcgcgg aagcccccgc cgtggcgatc tgctcccagg cgtacttctt
    13621 gatctccgcg cgcacctggg tgcgatagcg ctcccgtggg ccgctcgcgt ccgtcgtcgc
    13681 catggcctgc caccttcccc gtttatgtgg ctacaccttc aagatgtggt tagaggctat
    13741 cacggacctg ttgacccctc acttcgcatc gcgttataac ttctaacgaa ggttcgagct
    13801 tctagcctgc ctgctaaccg gctgacaagg ggaaaatcgt gtccggtatc cgcagcaccc
    13861 gcgtccgcgc tgccctgttc accgtcccgc tcgtcgccat cggcctcctc ggcatcgctg
    13921 ccgcgccggc cggggccgcc gccaccgcca ctcaccccgt caagtccctc acctgccgcg
    13981 gggaaggcgt cgaccccgac gccctcgtcc gctcccggac cgagaccgtc atccacgcac
    14041 cgctgcgcac catctggaag ctgcagaccg acgtggagcg ctggccgtcc tggcaaggcg
    14101 gcatcacggc catgaagcgc ctcgaccatg gtccgttccg caagggttcg gcgttccggt
    14161 ggacgacccc ggtgcctccc aaccccacga ctcccgccac cagcctggag atcacctcaa
    14221 ccgtcgaaca gctcaagcgc gactcctgta tccgctggac cggtcccgcg gtcgccgagg
    14281 gtctgcgcat cgacggcgtc cacgtatgga acttcacccg ggtcaagggc ggcgtccgtg
    14341 tgagcaccga agagacccat accggtgccg aggtcgaagc ggacgtccct gccgcgaccg
    14401 aaatcctcca ccagggcctc gaagcatggc tgcgcgacct caagaccacc gccgaagcca
    14461 ccacccacaa ccggccgcac tgaacgaaca gccagccccg gacctatgcc gccgttcccc
    14521 tcggcctcat gcgagaggag ggcggcggcg acgcccggac aagccctagc gcggcacggt
    14581 gtcgtccgcc tcgaacgggc cgccgtggcc gggcacgatc aggtcggcgg cggccagcac
    14641 gcgaagccgg gaggcgcgca gtacctcgcg gtccggggcg acggggtcgt ccgccggccc
    14701 ttccgagtgc caccacaggt cgccggcgaa cgccaccacg ccggagtccg tgccggccag
    14761 gagcgtgatg tcctcggggc tgtgtcccgg agtgcggatc agccggagcg acggggtcag
    14821 ttcgtagccc tccgcgtccc ggttcttcca ctggtcgccc cggtactcca ccttgtggtc
    14881 atggacccgg gcccggccga acaggcccac gttcatggtg ttgtccgggt ggtggtggct
    14941 gagcaccacg tcggtgatgt cgtcgggccc gagccccaac tccgcgagcg ggccgaggat
    15001 gtggtcgcgg tgggccacca tgcccgggtc gaagatgaca tgccggccgg cgtcggagac
    15061 gtacgagacg gtggcggcga ctccgggtcc ggtggagccg acgtagccgg tggtcaggat
    15121 cgtgtacacg gcgctgcggc cgagcggtgc gtctgtcatg gcctcaatgc ttccgggccg
    15181 gcctgccgtt cacgagtggc acatctgccg ctgatcgcag gtttcgtgcc acactgctca
    15241 cgtgcctcct ttcgctaccg tcgccgcgta cgccccgccc ggagtcggca tgctggccgt
    15301 cggcatcgtc accgaggtgt tcgccccgcg cggggagggg ctgcccggct tcgacttcgc
    15361 cctgtgcacc gaccggcccg ggccggtccc caccgacgtc ggcgtaccga tcgccatcga
    15421 gcacggcctg gaccggctgg ccgcagccga tctggtgatc gccctgccat gggccgattt
    15481 ccgcaccccg cccggtcccg ccgtgctcga cgcgctgtcg gccgcacacg aacgcggttc
    15541 gctggtcgcc gcccactgcg tcggcgcgtt cgcgctcgcc gccgccgggc tgctcgacgg
    15601 ccgacgcgcc accacccact ggcggttcgc cgaactgctg gcccgtcgcc acccggccgt
    15661 caccgtcgaa cccgacgccc tctacatcga cgaagggcgg atcaccacgg gagcgggagc
    15721 cgccgcgggc ttcgatctgt gtctgcacct gctgaggcgg gagtacggag ccgcgatggc
    15781 caacgccatc gcccgggaca tggtgctgcc cgcccaccgc gacggcgggc aggcgcagta
    15841 cctggccgct cccgtcccgg agaactgcca ggacgagcgg ctcgccgagg tgctcgcctg
    15901 ggcccgcgag cacctccacg aaccgcttcc cgtcgcggag ctggcccgtc gcgccgtgat
    15961 gagcaaacgc tccttcgccc gccgcttcgc cgccgccacc ggaaccaccc cgcacgcctg
    16021 gctccgcggc ctgcgactga gcagcgccga ggaactcctg gagaccacgg acctgccggt
    16081 cgaggagatc gcccgccgcg tgggatacgg gagcgcggcc gtcctgcgcg aacagttcgt
    16141 gcgccgccgg ggagtgccac cccgctccta ccgccgctcc ttcaccagcg cgccgtagcg
    16201 gatcacgtga agcgggacaa gagcgatcgg tgtgctcaat cgacgtgtgc ggtcagggcc
    16261 gcgtcgaccg cagcctccgc atgcaagcgg gcggtgggga agagcggtac ggggctgtcg
    16321 tcggcgccga tgaggagctc gatctcggtg caccccagga tgacgccctc ggcacccgcg
    16381 tcgacgagct cctcgacgac cttgcggtag gccgcacgcg actcgtcgcg gacgacgccc
    16441 atgcagagct cctcgtagat cacccggtga acgagcgcac gtccctcgga gtccgggacg
    16501 cacacgtcga gcccgccggc cgcgaggcgg ccccggtaga agtcctgctc catggtgaac
    16561 gcggtgccca gcagccccac ccggcgcagc cccgcggcgc ggacggcggc tgcggtggcg
    16621 tccgcgaggt gcaggagcgg gaccgaggtc gcggcctcga cggagtccgc gaccttgtgc
    16681 atggtgttgg tgcagatgag cagcagatcg gcgccggccg cttccaacga ccgggcggcg
    16741 tcggccagga cctcgccggc ctccgcccag cgcccctgga cctgcagctg ctcgatctcc
    16801 gcgaagtcca cggagtggag cacgcagcgg gccgaatgga gaccgccgag ccgctcgcgc
    16861 gtccgctcgt tgaggatccg gtagtactcc gccgtcgact cccagctcat cccgccgatc
    16921 agcccgatcg tcttcatgcc cgtgtccacg cccatgctcc tgctccttgt acggcaccgc
    16981 gttcacacga accataaggc agcaggcgga tgtgtcgcac tctcataaga gttgctttga
    17041 gtgcttcaag gtgtggcttg ccagaagtcg gttgcagaca gcggacttgc gaatgggatt
    17101 tcctacgggg tgcggaaccg accaccactg cgcaggtctt cctcgatcat ggctgccggg
    17161 cccgccgcca ggcgctgccg gaggcggtcc tcgttggcgg gccgctccgg ccctgcgacg
    17221 tagtggcggg ggtgttccag atggaggcag gcgagggagg cgccggtgtg ccagaggcgg
    17281 atcagcgggg cgcgtgagac gagcttcacc agcaggtcgt cgtcctcgca gccccagccc
    17341 gcgtaggccg cacagtatcc gccgatctct gcgaaccggt ctgccggcag caggagttgc
    17401 ccccagtgga agggcgcctg acgctgcatg tacttcggga ggccgggatc gtacgcggcc
    17461 cgtggcggcc agaccatcgg ggtgggcacc tgcagagcgc ccactcccag tacttcccat
    17521 tcgagccgtt caccggtgtc ggggacgagg gccggaccgg gcgccgccct gacgtagcat
    17581 gaccgcccga ccgtcgccgt cacccgcatg ccgacggctt ccgcgagaac ggtgccggta
    17641 cgggcgaggg cctcgacacc accgggaagc cggtacatcc agggctgggc gagagcagcg
    17701 tctcccgcca ggtccaggca ccgccgcaga tagtcccggc cgagcgggag gacgtcggcg
    17761 tccgtcaggc acaggagggg cgagcgggca gcggcggcgg cgatgttgcg cagcacgccc
    17821 gccgaccgga tgcccgggtc ggcgcggatc acccgtaccc ccgggaggac tgcggcgagg
    17881 tccccggcaa ggtcccccgc ggtcgcgatc accacctcgc agggtacgtc ctgcgccagc
    17941 caggccccgg cgacggtggc gaggcaggcg cggccccggt ggtccccgta gagcgggatg
    18001 gcgatggtca cttcgggcat gagggaccct cctgcagggt gcggcgccga cgggccgagt
    18061 ggctgatctc gatgcggttc ttccagaggt gcaggaggtg gtggcaggcg gcggggccct
    18121 gtgcggccac caggtctgcg tgcttggcga ggatgtactg gtgctcttcg aggaacagct
    18181 cgccggggga ggcgaaggtg agcgatgcgg cgtgccgccg gtaggagaag aggacacgcg
    18241 ggatgacgtc gcccgggtgc ccggcgcgct ccagccggat gagcagttcc acgtcgtcga
    18301 gggtgggcag ccgctcgtcg tagccgccga tcgcggtcag cgccgagcgg cgcaggaggc
    18361 gggtgcgttt gccgccggtg ttgaggaagg gcatcaggcc ggggacggtg ccgaggggtg
    18421 cgtcgaccgt gtccacgagg tcgaagtgcc tcacgtagca ggtgacatgg cccagatcgg
    18481 gggcgcggcg cagggcggcc acggcggtgg cgacacagtc gggctgcagc aggtcgtccc
    18541 cgtcgagcgg gaggatgaac tccccgcgcg ccgcggcgac gcccgcgttg taggccgatc
    18601 cgggaccgcc gttgggcttg tcgaccttga cgacgccggt cagtgcgtcg aaggcggcgc
    18661 gggtcgcggg gtcggtggag ccgtcgttga cgaccacgac ctcgacccgc gggtgggtct
    18721 gcgcgcggac ggaggcgagg gtgtcgggca accagcggcc cttgttgtag acggcgatca
    18781 cgacggagac ggtggggagc atgccgccgg cggatccggt ccgcgggggg cggcgcgctt
    18841 cgcggtagtg gccgacgagc cgtcgagcgg cgtcgacggg gtcaccgtag gcccgggcgg
    18901 cggcgggcgc gcggcgtgcc gcctcgccca ggagccggtg gtcgtcgccg gtgagccggc
    18961 ccagcaggcg ggccagcgcg cccgggtcgt ccgcgggggt gatgaaaccg gccccctggt
    19021 ccgtgaccac ctccgccgtg ccaccgccgg aggtacacac caccgggcag ccgtggctca
    19081 tcgcctccag cgcctcgtac gggcagttgt cccagcgggc cgggaccacg cagaggcggc
    19141 tgttccgcca gaggtgcgcc cggtcgggta cttccgcggg gtcgaggaag gagacgcgtc
    19201 cgcgcagcgg cccggtgacg agccgggcga ggtgctggtc gtaggggagc ccgagccgcc
    19261 ggtgggcgct ccgggggccg aacagggtga aggtgacgtg cgggtcggcg cgggcgaggc
    19321 gggcggctgc ggccaggaag acgtcggctc cgcccagggg gctcagcggg cccgcgaacg
    19381 tcacctgccg ggggcccgcg gacgtcactt ggaggtcggc ttgggggatg gggcaggggc
    19441 tgtagcggca cctgctgttg agcgcccgtg cgtatccggc gacgcgtcgc gaagggagca
    19501 gcagcaggtc ggcgtggcgc aggcagtagt cctcggcgta tgcggccatc gcccggtcgg
    19561 tgtcgcccgg ctgctccccg ctgaacggag cggtcagcgc ggcgggtgcg tgcagccgta
    19621 cggtgagcgc agtgtccggg aactcgccga gcaggcgctt ggcccggatc gtggtcaggc
    19681 cctcgccgtc gcggtcggcg aactccaccg cgtcgaggcc gggccctgtg gtggcgaggg
    19741 tccgcagggc ccggtagacc cggtcggcgt gggcgtgcgc cggtgtcagg taggtgtggc
    19801 tctcgtccgg tgccggcagc ggaacggcct ggagtccgtg gcgcccggcg gtcgcgaagt
    19861 ccccggtggc cgccagcaga cggacggagt ggccttcgcg caccagctgc cggccggcgt
    19921 tgaggacgta gcggctcacc tggtcccacg acggggagaa gtcgcgtacg accagggcca
    19981 cccgcaggct cggtcgcacg ccggcccccg cctccgccct caccgccggc ggtagcactg
    20041 gtcgcccacc gccatgatgt cgacgccccg cttctggcag tagtgcgtca ggtcggacat
    20101 gtggttgatg aatccgtgac cgttgaagtt gagcgaggtg ttgcacagca cccccgcccc
    20161 gtactgcgcg gcgaaggccg agagcagggt gtgcagggcg gcgttgtcgc cgggcgaaac
    20221 ggtctggacg cgggcggagc cgtcgacgtg ggtgacggcg cgcaggtcca cggaacgcac
    20281 cttgcggaag tagagcatgt acgggtcctc gaagccgccg tggaagaggg cgtcggtgtc
    20341 ctccacgcgg cagcagggcg cgatgggccg gtagtcctcc cgcttcttga tggcgttgag
    20401 ccgctccttc gtgctctccc ggaacggttc cgcgagcagc gagcgatggc cgagcgcgcg
    20461 tggcccgatc tcccagcggc cctggaccca ggccaccacc gcgccctcgc cgatggcccg
    20521 ggccagggag gcgtggtcga gcgcggaccg gtgccacacc gccgggtcgg gctcggtgtc
    20581 gtggacgaag tccaggccgc tgtagacgtt ccagtcgagg tgcgggtcac cggtgagcgc
    20641 ggccagggcg tcggcggcgg tgccgatggc cgagccggag tcgttggtga cgggcggcac
    20701 gaacacggag gagaagtgac cgaggtcggc ccacagggcg ttccagtcgc agttcagccc
    20761 gcagcccccg gaaatgagca gcggtgtgcc ggcgggcagg tgcgtgcggg cggcgtccgc
    20821 gaagatcccg aagagccggt tgctcagcag ggctgccgcg gctttggtct gcggtgactc
    20881 gacaccggcg tcgtagagcg gggtgtcccg gaaggcttcc ttgggcggcg gatagacgga
    20941 cggcagggcg aggatccggt cgaccgcccg tacgatctcc cggtccgcgt cgccgggttc
    21001 cgcgtaggcg gccaaggcca tcagctttcc cgcatccccc aggcggggcg ccgcggcccg
    21061 cggctcga
//
