LOCUS       NZ_CP013141            22269 bp    DNA     circular CON 12-MAY-2024
DEFINITION  Lysobacter antibioticus strain ATCC 29479 chromosome, complete
            genome.
ACCESSION   NZ_CP013141
VERSION     NZ_CP013141.1
KEYWORDS    RefSeq.
SOURCE      Lysobacter antibioticus
  ORGANISM  Lysobacter antibioticus
            Bacteria; Pseudomonadota; Gammaproteobacteria; Lysobacterales;
            Lysobacteraceae; Lysobacter.
REFERENCE   1  (bases 1 to 5765176)
  AUTHORS   Kobayashi,D.Y. and Ravel,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (04-NOV-2015) Plant Biology & Pathology, Rutgers, The
            State University of New Jersey, 59 Dudley Road, New Brunswick, NJ
            08901, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: TiGR Assembler v. 2
            Genome Coverage                   :: 200x
            Sequencing Technology             :: Sanger; 454 FLX
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001442535.1-RS_2024_05_12
            Annotation Date                   :: 05/12/2024 11:28:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,784
            CDSs (total)                      :: 4,717
            Genes (coding)                    :: 4,635
            CDSs (with protein)               :: 4,635
            Genes (RNA)                       :: 67
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 82
            CDSs (without protein)            :: 82
            Pseudo Genes (ambiguous residues) :: 0 of 82
            Pseudo Genes (frameshifted)       :: 12 of 82
            Pseudo Genes (incomplete)         :: 74 of 82
            Pseudo Genes (internal stop)      :: 2 of 82
            Pseudo Genes (multiple problems)  :: 6 of 82
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:11:48
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3676612
            Orig. end                         :: 3698881
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP013141.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22269
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="redox-cofactor"
                     /region_number="11"
                     /rules="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /tool="antismash"
     cand_cluster    1..22269
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(PF04055 and (TIGR04085 or SPASM))
                     and (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /kind="single"
                     /product="redox-cofactor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22269
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12269](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12269
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(PF04055 and (TIGR04085 or SPASM)) and
                     (TIGR02111 or TIGR03966) and minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE]))"
                     /neighbourhood="10000"
                     /product="redox-cofactor"
                     /protocluster_number="1"
     gene            complement(1028..1696)
                     /locus_tag="GLA29479_RS14835"
                     /old_locus_tag="GLA29479_3361"
     CDS             complement(1028..1696)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011257949.1"
                     /locus_tag="GLA29479_RS14835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3361"
                     /product="response regulator transcription factor"
                     /protein_id="WP_057918888.1"
                     /transl_table=11
                     /translation="MSETLRLLIADDHPMFRAALRYALGEIAPGASIVEVSSQSALEAA
                     IASGEEFDLAMLDLMMPGAMGFSSLVYARGERPELPVVIISSNEHPRTIRRAQQFGAAA
                     FVPKSAPTTMLGEAVKAVLAGDIWFPPQKAERDEHDAQLADKLALLTPQQLRVLMRLAD
                     GLLNKQIAYELSLAENTVKIHVTAILRKLGCHSRTQAAVLVKGLSLEDEGADLHGSTTQ
                     "
     gene            complement(2015..3001)
                     /locus_tag="GLA29479_RS14840"
                     /old_locus_tag="GLA29479_3362"
     CDS             complement(2015..3001)
                     /EC_number="1.1.1.37"
                     /GO_function="GO:0016615 - malate dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006108 - malate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012439107.1"
                     /locus_tag="GLA29479_RS14840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3362"
                     /product="malate dehydrogenase"
                     /protein_id="WP_057918889.1"
                     /transl_table=11
                     /translation="MKTPVRVAVTGAAGQIGYSLLFRIASGEMLGKDQPVILQLLELPL
                     EKAQAALKGVIMELEDCAFPLLAGVIGTDDAEVAFKDVDVALLVGARPRGPGMERKDLL
                     LENAKIFTAQGAALNKVASRDVKVLVVGNPANTNAYIAMKSAPDLPAKNFTAMLRLDHN
                     RALSQLAAKAGVAVGDIDSLIVWGNHSPTMYPDYRFAKAGGVSLKDKINDAAWNADSFI
                     PTVGKRGAAIIEARGLSSAASAANAAIDHIRDWVLGSNGKWVTMGVPSDGSYGIPEGVM
                     YGVPVITANGEYTRVEGLEIDAFSRERMDKTLAELEEERAGVAHLLG"
     gene            complement(3119..3496)
                     /locus_tag="GLA29479_RS14845"
                     /old_locus_tag="GLA29479_3363"
     CDS             complement(3119..3496)
                     /GO_function="GO:0015035 - protein-disulfide reductase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013535965.1"
                     /locus_tag="GLA29479_RS14845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3363"
                     /product="glutaredoxin domain-containing protein"
                     /protein_id="WP_031373214.1"
                     /transl_table=11
                     /translation="MRVLTVLLILGLAGGAYALAYKGDTAWFATRQAELKPDDPRHQTG
                     DKRIVMLAAEWCGYCEKLRKDFELADVRYSIIDIDTPAGQRAMSAVGARGVPVTIVGQE
                     IVYGYDMDEIKDRLKPLGYRL"
     gene            complement(3541..4746)
                     /locus_tag="GLA29479_RS14850"
                     /old_locus_tag="GLA29479_3364"
     CDS             complement(3541..4746)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (31-386). E-value:
                     1.4e-63. Score: 207.2. Matches aSDomain:
                     nrpspksdomains_GLA29479_RS14850_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007509893.1"
                     /locus_tag="GLA29479_RS14850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3364"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_057972061.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.1e-61, bitscore:
                     207.1, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQLARRIGRAKPSAIMQVAEKAKRLKAEGRDIISFSIGVPNFLP
                     GDHVYAAVRDALAKDSGQYGSNRGADALLDAFIEHMGKIGLTGYGRVNVATGIGAKHVI
                     YNIAEALLDEGDTIAFPTPYWTSYLDIAEIVNAQIDLLPCPASQDYKLTPAQLDAALAK
                     KPKVFLFNNPSNPTGMVYGKEEIDALADVVAKYPDTWIITDDIYNRMVFDGLGYHNFVH
                     ARPELRDRVIFIDSLSKTYGMPGWRVGFMAGPESVAQAVTTMNSNHITNVPEVVTAAAV
                     AALSGPQDVPTQKCAEFQAKRDQVMAVMNAIPGVVCPRPQGAFYVFPDISVAFGKTHVP
                     SGLKIGNDMDFCSALLETKGVACVPGSAFGEPRALRISYTCPTPQLAPGLQRFQEFFAE
                     LV"
     aSDomain        complement(3589..4653)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GLA29479_RS14850_Aminotran_1_2.1
                     "
                     /evalue="1.40E-63"
                     /label="GLA29479_RS14850_Aminotran_1_2.1"
                     /locus_tag="GLA29479_RS14850"
                     /protein_end="386"
                     /protein_start="31"
                     /score="207.2"
                     /tool="antismash"
                     /translation="DIISFSIGVPNFLPGDHVYAAVRDALAKDSGQYGSNRGADALLDA
                     FIEHMGKIGLTGYGRVNVATGIGAKHVIYNIAEALLDEGDTIAFPTPYWTSYLDIAEIV
                     NAQIDLLPCPASQDYKLTPAQLDAALAKKPKVFLFNNPSNPTGMVYGKEEIDALADVVA
                     KYPDTWIITDDIYNRMVFDGLGYHNFVHARPELRDRVIFIDSLSKTYGMPGWRVGFMAG
                     PESVAQAVTTMNSNHITNVPEVVTAAAVAALSGPQDVPTQKCAEFQAKRDQVMAVMNAI
                     PGVVCPRPQGAFYVFPDISVAFGKTHVPSGLKIGNDMDFCSALLETKGVACVPGSAFGE
                     PRALRISYTCPTPQL"
     gene            complement(5150..5656)
                     /locus_tag="GLA29479_RS14855"
                     /old_locus_tag="GLA29479_3365"
     CDS             complement(5150..5656)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009607495.1"
                     /locus_tag="GLA29479_RS14855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3365"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_031373212.1"
                     /transl_table=11
                     /translation="MSLIATFDTDRGPIRVELAADKAPLTVANFVNLAQRGFYDGLNFH
                     RVIPNFMIQGGCPQGTGTGGPGYRFEDETRNGLGHQRGVLSMANAGPGTNGSQFFITHI
                     VCDWLDGKHTVFGKVLEGLDVVDAVKQGDKIKSVKIEGDVAGALAAKAERVADWNKVLD
                     ENARA"
     gene            5986..7815
                     /gene="typA"
                     /locus_tag="GLA29479_RS14860"
                     /old_locus_tag="GLA29479_3366"
     CDS             5986..7815
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /GO_process="GO:0006950 - response to stress [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="typA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014161352.1"
                     /locus_tag="GLA29479_RS14860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3366"
                     /product="translational GTPase TypA"
                     /protein_id="WP_057918891.1"
                     /transl_table=11
                     /translation="MSIERLRNIAIVAHVDHGKTTLVDCLLKQSGTLSERTVLAERAMD
                     SNDQEKERGITILAKNTAITWQGNRINIVDTPGHADFGGEVERVLSMVDSVLILVDAMD
                     GPMPQTRFVTQKAFAMGFKPIVVVNKIDRPGARPDWVIDQVFDLFDKLGATNEQLDFPI
                     VYASALHGYASLDDAARSGDMTPLYEAIMKHVAPPQVDLDGPFQMRISQLDYSNFVGLI
                     GIGRIQRGKVRRNMPVSVVDRNGKKRQGKVLQVLGFMGLERLETEEAEAGDIVAISGVA
                     ELSISDTVCALDTPEALPALTVDEPTISMTFQVNNSPFAGNKELSGGKFLTSRQLRERL
                     ERETLHNVALKVEEGSDPDKFLVSGRGELHLSVLIENMRREGFELAVSRPEVIIKEIDG
                     QQMEPVEQLVVDIEEQHQGGVMEKLGTRKAQLKNMEPDGKGRVRLDYMIPARGLIGFQN
                     EFRTLTQGSGLLFHVFDHYGPKEQGAIAKRINGVMIANAPGATPAYSLGPLQERGRLFA
                     AEGDNVYEGQLIGIHSKDNDLTVNAIKTKPLTNMRASGKDDAIQLSPAIKYTLEQALDF
                     IEDDELVEVTPKEIRLRKKFLTESDRKRASRAA"
     misc_feature    5993..6008
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.56"
                     /tool="antismash"
     misc_feature    8006..8019
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: strong, score: 19.46"
                     /tool="antismash"
     gene            8179..8652
                     /locus_tag="GLA29479_RS14865"
     CDS             8179..8652
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005993406.1"
                     /locus_tag="GLA29479_RS14865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2127 domain-containing protein"
                     /protein_id="WP_057918892.1"
                     /transl_table=11
                     /translation="MTPTDPDYDSDPKAHPGLHLIAAVEAIKGLLALSAASGLELLGPA
                     PLQRWIEELIKRFHLDPEHGSLAWLAQAISPHSVHLAAGVVLAYGLLHLIEAWGLWKAK
                     AWASWLGCIGAALYLPFDLYALYRHPGWLAIAVLIINVIVVWVLGRDLFKRRR"
     misc_feature    complement(8821..8834)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.58"
                     /tool="antismash"
     gene            9055..9987
                     /gene="pqqB"
                     /locus_tag="GLA29479_RS14875"
                     /old_locus_tag="GLA29479_3369"
     CDS             9055..9987
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011038060.1"
                     /locus_tag="GLA29479_RS14875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3369"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /protein_id="WP_057973213.1"
                     /transl_table=11
                     /translation="MHIVVLGAAAGGGYPQWNCNTPGSRRAWRQEPGHKRRSQASIAVS
                     ADGERWLLINASPDFRQQVLAIPRLWPQRGLRHSPIEAVLLTSGEIDHIAGLLSMRERQ
                     RFDLWASARVLQLLRDNAIFDALDPEYVTRRALTLDAPLDVAGLDAPFGLRVTAFSVPG
                     KVPLFMESRSGGDLAGSAEETVGLEISDGSQRCFYIPGCAAMTPALRERLRGAALVFFD
                     GTLWRDDELIRAEVGHKTGARMGHMNILGQGEGDAGGTLAAFADLDVQRKLFIHLNTTN
                     PVLDEASPERAHVAAHGWEVAEDGMEIRL"
     misc_feature    9553..9555
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            10001..10813
                     /gene="pqqC"
                     /locus_tag="GLA29479_RS14880"
                     /old_locus_tag="GLA29479_3370"
     CDS             10001..10813
                     /EC_number="1.3.3.11"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR02111"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017155549.1"
                     /locus_tag="GLA29479_RS14880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3370"
                     /product="pyrroloquinoline-quinone synthase PqqC"
                     /protein_id="WP_057972062.1"
                     /sec_met_domain="TIGR02111 (E-value: 4.9e-118, bitscore:
                     390.8, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAHAVEADPSEQRIADDALLTPAQLEARLRAIGAERYHDKHPFH
                     ALLHSGRLNRGQVQAWALNRFEYQRCIPLKDAALLARIEDPDLRRIWRQRIVDHDGERA
                     GDGGIARWLHLTDALGLDRDLVESGRGLLPATRFAVQAYIHFVRERSLLEAIASSLTEL
                     FAPNIIGQRVAGMLAHYDFVSKPALAYFDSRLHQAPQDAHFALDYVKQHARSREQQDAV
                     CAALRFKCEVLWSMLDALYLAYVGNAPGEGRIDMIPPGAFRPDPEPGA"
     gene            10810..11106
                     /gene="pqqD"
                     /locus_tag="GLA29479_RS25770"
                     /old_locus_tag="GLA29479_3371"
     CDS             10810..11106
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PqqD_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003482513.1"
                     /locus_tag="GLA29479_RS25770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3371"
                     /product="pyrroloquinoline quinone biosynthesis peptide
                     chaperone PqqD"
                     /protein_id="WP_057918893.1"
                     /sec_met_domain="PqqD_RRE (E-value: 1.2e-32, bitscore:
                     109.6, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 9.9e-16, bitscore: 55.9,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 1e-08,
                     bitscore: 33.2, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATIDARAVPRFPAGVRLQHDRAREQWVLLAPERVVELDEIAHA
                     VLARVDGTADIAAIVDALAAEYGADAEQVRGDVLELFANLLDKRMLAVAAPAS"
     aSDomain        10819..11085
                     /aSDomain="PqqD_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing protein in a pyrroloquinoline
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GLA29479_RS25770_PqqD_RRE.1"
                     /evalue="7.20E-35"
                     /identifier="RREFam006.1"
                     /label="GLA29479_RS25770"
                     /locus_tag="GLA29479_RS25770"
                     /protein_end="92"
                     /protein_start="3"
                     /score="109.6"
                     /tool="antismash"
                     /translation="TIDARAVPRFPAGVRLQHDRAREQWVLLAPERVVELDEIAHAVLA
                     RVDGTADIAAIVDALAAEYGADAEQVRGDVLELFANLLDKRMLA"
     aSDomain        10921..11085
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_GLA29479_RS25770_Stand_Alone_Lasso_RR
                     E.1"
                     /evalue="6.10E-11"
                     /identifier="RREFam002.1"
                     /label="GLA29479_RS25770"
                     /locus_tag="GLA29479_RS25770"
                     /protein_end="92"
                     /protein_start="37"
                     /score="33.2"
                     /tool="antismash"
                     /translation="ELDEIAHAVLARVDGTADIAAIVDALAAEYGADAEQVRGDVLELF
                     ANLLDKRMLA"
     gene            11103..12269
                     /gene="pqqE"
                     /locus_tag="GLA29479_RS14890"
                     /old_locus_tag="GLA29479_3372"
     CDS             11103..12269
                     /GO_process="GO:0018149 - peptide cross-linking [Evidence
                     IEA]"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pqqE"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: SPASM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: PF04055"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     redox-cofactor: TIGR04085"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011258495.1"
                     /locus_tag="GLA29479_RS14890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3372"
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqE"
                     /protein_id="WP_169795670.1"
                     /sec_met_domain="PF04055 (E-value: 2.4e-21, bitscore: 74.9,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.4e-10, bitscore:
                     37.9, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1e-09, bitscore: 36.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAATPSPTPAAAVAPPLRAERVPAPPLAVLLELTHRCPLSCPYC
                     SNPLQLVGLRDELATADWLRVLGEAAELGVLQVHFSGGEPTLRKDLPELLQHARSLGLY
                     CNLITSGVGVERERLLALQQAGLDHLQLSIQDSEERGADRIAGYAGSHRRKLALARWCG
                     ELGLPLTLNAVVHRHNAERVAAMIELALDLGAGRLEVAHTQYYGWGLKNRAALMPTRAQ
                     LDAVTAVVEDARLRLRGTLTIDYVTPDYYARRPKACMGGWAQRFVNITPEGKVLPCHAA
                     ETIADLHFDSVRERGLGEIWRESDAFQRYRGTDWMPEPCRGCERREIDWGGCRCQALAL
                     SGRADTLDPVCDRSPDHAGVRELAERESQAPAPEFVYRKIRPAGNRAP"
     gene            12418..14052
                     /locus_tag="GLA29479_RS14895"
                     /old_locus_tag="GLA29479_3373"
     CDS             12418..14052
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019237915.1"
                     /locus_tag="GLA29479_RS14895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3373"
                     /product="amidase"
                     /protein_id="WP_082638707.1"
                     /transl_table=11
                     /translation="MSATPALRLSAVALVLAVAGCASSGTPRPTRPAVPADLPRGFLPA
                     DPLRLTETDSATLAARMAAGDFSSSKLTQAYLDRIAALDDDGPRLNAVIELNPNALAEA
                     RALDEERKAGKLRGPLHGIAVLIKDNIDATPMVNSAGSLALAAHRPRQDAPLVAALRQA
                     GAVILGKTNLSEWANFRSTRSISGWSGRGGLTRNPYALDRTACGSSSGTGAAIAASLAT
                     LGVGTETDGSILCPAAMNGLVGFKPSVGLVSRAGIIPISHSQDSAGPMARNVTDAARLL
                     SVLAAADAGGDAAAQAAAGKRIDDYVATLDAESLRGARLGFIRDAGVKTPPSIDAVLER
                     TFKGMRDAGATIVEVRMPTAGQWDAAEFQVLLYEFKDGVERYLREHDAPVKTLSELIAF
                     NRANAATEMPYFDQELLEQANKKGSLKDAAYRKAAARARQLAGAQGIDAVMKRHKLDAL
                     IAVATTPAFMVDAVNGDPFGGASWGAAAVAGYPSLTVPLGEASGLPVGMVFMGRRWSDA
                     KLLSLGYAFEQLTQARTAPRYRATLNP"
     gene            complement(14124..14993)
                     /locus_tag="GLA29479_RS14900"
                     /old_locus_tag="GLA29479_3374"
     CDS             complement(14124..14993)
                     /NRPS_PKS="Domain: Abhydrolase_1 (12-273). E-value:
                     4.9e-28. Score: 90.3. Matches aSDomain:
                     nrpspksdomains_GLA29479_RS14900_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012770.4"
                     /locus_tag="GLA29479_RS14900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3374"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_169795671.1"
                     /sec_met_domain="PF00561 (E-value: 1.9e-23, bitscore: 81.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.1e-15, bitscore:
                     54.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLSLVREPGTGPVVLYVHGATFPCELSIGWRMDGRSWLDHLQAQ
                     GFDAWGLDFAGYGYSQRPEVFRAAADSAPPWGDYRMGAAQIAAAIAAIRRERPHAPIHL
                     LAHSWGTLPARQAAIEHPDAVSKLVLFGPVSTREGPPGNEPKPAWTLIGAADQRPRQRS
                     GLPADAATPVGAQELERWCRAYLASDEASATRNPPSVRIPTGPMADIDRLWAGQALVDN
                     TRLRQPTLIVRGEWDHVTTDADAARLYAELSGASERRDVKISGGNHWLHLQPRRTALWS
                     TTAAFLRD"
     aSDomain        complement(14175..14957)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GLA29479_RS14900_Abhydrolase_1.1
                     "
                     /evalue="4.90E-28"
                     /label="GLA29479_RS14900_Abhydrolase_1.1"
                     /locus_tag="GLA29479_RS14900"
                     /protein_end="273"
                     /protein_start="12"
                     /score="90.3"
                     /tool="antismash"
                     /translation="PVVLYVHGATFPCELSIGWRMDGRSWLDHLQAQGFDAWGLDFAGY
                     GYSQRPEVFRAAADSAPPWGDYRMGAAQIAAAIAAIRRERPHAPIHLLAHSWGTLPARQ
                     AAIEHPDAVSKLVLFGPVSTREGPPGNEPKPAWTLIGAADQRPRQRSGLPADAATPVGA
                     QELERWCRAYLASDEASATRNPPSVRIPTGPMADIDRLWAGQALVDNTRLRQPTLIVRG
                     EWDHVTTDADAARLYAELSGASERRDVKISGGNHWLHLQ"
     misc_feature    complement(15176..15190)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.02"
                     /tool="antismash"
     misc_feature    complement(15320..15333)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.87"
                     /tool="antismash"
     misc_feature    15320..15334
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.5"
                     /tool="antismash"
     misc_feature    15644..15657
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    complement(15733..15748)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.3"
                     /tool="antismash"
     gene            complement(16048..17436)
                     /locus_tag="GLA29479_RS14905"
                     /old_locus_tag="GLA29479_3376"
     CDS             complement(16048..17436)
                     /EC_number="2.5.1.54"
                     /GO_function="GO:0003849 - 3-deoxy-7-phosphoheptulonate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011036136.1"
                     /locus_tag="GLA29479_RS14905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3376"
                     /product="3-deoxy-7-phosphoheptulonate synthase class II"
                     /protein_id="WP_031373809.1"
                     /transl_table=11
                     /translation="MSASDRNLRAVNLPADWTPTSWRERTALQLPNYPDAAELESALQE
                     LRHLPPLVTSWEILSLKQQLAEAQEGKRFLLQGGDCAESFDQCSSDVISNRLKVLLQMS
                     LVLVHGMRKPVVRVGRFAGQYAKPRSADTETIDGVTLPSYRGDMVNAPAFNEAARKPDP
                     RRMIKAHARSAMTMNFVRALIDGGFADLHHPEYWNLSWVGHSPLADEYRRMVNAIGDAV
                     RFMETLSGSEVHNLNRVDFYTSHEALLLPYEESLTRQVPRHWGFFNLSTHYPWIGMRTA
                     AVDGAHAEYFRGIRNPIALKVGPSVTPDQLLRTIDLLNPEDEPGRLTFIHRMGASHIAE
                     KLPPLLDAMRRDGRRVLWVCDPMHGNTESTSNGYKTRRFRNIRAEIETSFELHAAAGTR
                     MGGVHLELTGEDVTECLGGARELTESDLDRAYRSTVDPRLNYEQALEVAMLIVRKQAQI
                     AAPA"
     misc_feature    17407..17420
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     misc_feature    complement(17429..17440)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            complement(17497..17997)
                     /locus_tag="GLA29479_RS14910"
                     /old_locus_tag="GLA29479_3377"
     CDS             complement(17497..17997)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005993394.1"
                     /locus_tag="GLA29479_RS14910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3377"
                     /product="disulfide bond formation protein B"
                     /protein_id="WP_057918896.1"
                     /transl_table=11
                     /translation="MNPFKASFRTQYLLGFLACTGLLAYAFYLQLYQHLEPCPLCIFQR
                     VAFFALGLVFLAGALHGPKKAGGRRSYGVLALLASLAGIAVAGNHVRLQHLPPDQVPAC
                     GPGLDYMLDAMPIAGVIRKVMTGSGECAAVDWSFLGLAMPAWSLICFIVLAVWAAYAAF
                     RRR"
     gene            complement(18305..18679)
                     /gene="rplQ"
                     /locus_tag="GLA29479_RS14915"
                     /old_locus_tag="GLA29479_3378"
     CDS             complement(18305..18679)
                     /GO_component="GO:0005762 - mitochondrial large ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022625 - cytosolic large ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rplQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004145464.1"
                     /locus_tag="GLA29479_RS14915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3378"
                     /product="50S ribosomal protein L17"
                     /protein_id="WP_031373811.1"
                     /transl_table=11
                     /translation="MRHQKSGRKFSRTSAHRDAMFTNMAASLIKHGLIRTTLPKAKELR
                     RVAEPLITLAKKDGVANRRLAFSRLRDKEAVGTLFVELGPRYASRPGGYLRILKCGFRA
                     GDNAPMAYVELVDRPQAAAE"
     gene            complement(18966..19964)
                     /gene="rpoA"
                     /locus_tag="GLA29479_RS14920"
                     /old_locus_tag="GLA29479_3379"
     CDS             complement(18966..19964)
                     /EC_number="2.7.7.6"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003899 - DNA-directed 5'-3' RNA
                     polymerase activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="rpoA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020852431.1"
                     /locus_tag="GLA29479_RS14920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3379"
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="WP_031373812.1"
                     /transl_table=11
                     /translation="MTVTANQVLRPRGPQIERLTGNRAKVVIEPLERGYGHTLGNALRR
                     VLLSSIPGFAITEVEIDGVLHEYTTVEGLEEDVLEVLLNLKDVAIRMHTGDASTLSLAK
                     QGPGIVTAGDIKTDHNVEILNTDHVICHLTKDTALNMRLKIERGFGYQPAASRRRPDEE
                     TRAIGRLMLDASFSPVRRVAYAVEAARVEQRTDLDKLVLDIETNGTIDAEEAVRTAADI
                     LTDQLSVFGDFTHRDRGAQKPATSGIDPILLRPIDDLELTVRSANCLKAESIYYVGDLI
                     QKTEVELLKTPNLGKKSLTEIKEVLAQRGLSLGMKLENWPPAGIASHGMMG"
     gene            complement(20118..20747)
                     /gene="rpsD"
                     /locus_tag="GLA29479_RS14925"
                     /old_locus_tag="GLA29479_3380"
     CDS             complement(20118..20747)
                     /GO_component="GO:0015935 - small ribosomal subunit
                     [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_function="GO:0019843 - rRNA binding [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004145446.1"
                     /locus_tag="GLA29479_RS14925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3380"
                     /product="30S ribosomal protein S4"
                     /protein_id="WP_031373813.1"
                     /transl_table=11
                     /translation="MARYIGPTCKLARREGADLGLKSSARALDSKCKLEQKPGQHGPTA
                     RKGKLSDYATQLREKQKVKRIYGLLERQFRNYYKKASTKKGNTGENLLQLLETRLDNVV
                     YRMGFAVTRPAARQLVSHRGVTVNGKSVNLPSYQVKAGDAIALSERAQKQLRVQESLTV
                     SSQMDLSPSWVEVDNKKFSGVFKAVPDRADLPADINEALIVELYSK"
     gene            complement(20762..21154)
                     /gene="rpsK"
                     /locus_tag="GLA29479_RS14930"
                     /old_locus_tag="GLA29479_3381"
     CDS             complement(20762..21154)
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017939146.1"
                     /locus_tag="GLA29479_RS14930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3381"
                     /product="30S ribosomal protein S11"
                     /protein_id="WP_031373814.1"
                     /transl_table=11
                     /translation="MAKPAAAKTKKKIKRVVTDGIAHVHASFNNTIITITDRQGNALSW
                     ATSGGAGFRGSRKSTPFAAQVAAEKAGRAALDYGVKSLEVRIKGPGPGRESAVRSLNNV
                     GYKIINIIDVTPIPHNGCRPPKKRRV"
     gene            complement(21167..21523)
                     /gene="rpsM"
                     /locus_tag="GLA29479_RS14935"
                     /old_locus_tag="GLA29479_3382"
     CDS             complement(21167..21523)
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsM"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002215453.1"
                     /locus_tag="GLA29479_RS14935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GLA29479_3382"
                     /product="30S ribosomal protein S13"
                     /protein_id="WP_031373815.1"
                     /transl_table=11
                     /translation="MARIAGVNLPAQKHVWVGLQSIFGIGRTRSKQVCESAGVTSTTKI
                     RDLSEPEVERLRAEVGKFVVEGDLRREVGIAIKRLMDLGCYRGLRHRRGLPLRGQRTRT
                     NARTRKGPRKAIKK"
     misc_feature    complement(22154..22169)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
ORIGIN
        1 ctgcgccgga tcgtgcagaa cttcctgtcc aacgccttgc aattcacccc gcgcgacggc
       61 cgcatcgtgc tcggcgcgcg gcgcctgggc gacagcctgc gcatcgaggt ctgggacacc
      121 ggccccggca ttccggccaa caaactcgag ctgatcttcg aggaattcca gcgcctggac
      181 ctcggcgtcg aggcgccggc gcgcggcgcc gggctgggcc tggcgatcgt acgtcgtgtc
      241 gcccaattgc tcggccaccg tatcgcagtg cgatcgtggc cgggccgcgg cagcgtgttc
      301 tcggtggaag tgccgtattc ggctacgcaa accgaaccgg tcgcggccgc ggcctcggac
      361 caaacccacg acagcgatgc ggtgctcgac ctcgacccgc tgctccgcgg tcggcgcgta
      421 tgggtgatcg acgacgaccc gcattcgcga caagccgcgc aaaggctgct cagcgactgg
      481 ggctgccatg tcgacactgc cgccgacgcg gccggcgccc tgcacatggc cgcgtcgctg
      541 agcatgccgg aactattgct gctcgattat cgtctcggcg aaagcaccgg cttcgaactg
      601 gccgtccaac tggaagccga gtgggagcgc atgccgccgg tggtgctgat gtcggccgac
      661 gccgacccca ccctgcgccc gcgcgctacc gaacgcggct ggagcttcct gcccaagccg
      721 ctcaaacccg ccgcgctgcg cgcgctgtcg atgcgattgt tgggccgggg cgcggttgaa
      781 gggtagagac ttggcttcga tcaagggctc gctccgaaca cccgatttcc ccgcgccgca
      841 tcgtcagcaa aaaagccgcc gtcgaaatcg cccctttgag aagggggctg cgccttgcgt
      901 ggtacgaggc ctgaactcgg ctcaatggcg cgggggattt gcttcagcgc tcactgcaaa
      961 gccaaaagca gcccctgccc cctttgcaaa ggggggagcc gcacatgggt ctcaacgcct
     1021 tcttccgcta ctgcgtcgtc gagccgtgca ggtccgcgcc ttcgtcttcc agcgacaggc
     1081 ccttcaccag caccgccgcc tgggtgcgcg agtggcagcc gagtttgcgc aggatcgcgg
     1141 tgacgtggat cttcaccgtg ttctcggcca gcgacagttc gtaggcgatc tgtttgttga
     1201 gcaaaccgtc ggcgaggcgc atcagtacgc gcaattgctg cggtgtcagc aacgcgagtt
     1261 tgtccgcgag ctgggcatcg tgttcgtcgc gttcggcctt ctgcggcgga aaccagatgt
     1321 cgccggccag caccgctttc accgcttcgc cgagcatcgt ggtcggcgcc gacttgggca
     1381 cgaaggcggc ggcgccgaac tgctgggcac gacggatcgt gcgcgggtgt tcgttggagg
     1441 aaatgatcac caccggcaac tcgggccgct cgccgcgtgc gtataccagc gaggagaaac
     1501 ccatcgcgcc cggcatcatc aggtcgagca tggcgaggtc gaattcctcg ccgctggcga
     1561 tggccgcctc gagcgcgctc tggctcgaca cctcgacgat gctcgcgccc ggcgcgatct
     1621 cgccgagggc ataacgcaac gccgcccgga acatcgggtg gtcgtcggca atcagcaggc
     1681 gcagggtctc gctcatcgga cagggtcccc ctcggacttc ggagcgggat cgatgctaca
     1741 cgctcgcggc cggtccggcg gcagtagacc cggcccttgt cgcgcttaag gaaggttgtc
     1801 gcagcgccgc aatgcgccga cgatgcgaat cgccatcccg ctgccctcat ccggccctgc
     1861 ggaccacctt ctcccgcaag cgggagaagg aacaaccgtc ggcgggaccc agggcgatcg
     1921 ccgcgcggaa gcatcggggc atccggccat ccagccccaa acaaaaacgg ggcggccaag
     1981 gccgccccgt tcatgcatcg cgatcgcagc gcgatcagcc cagcaggtgg gccacgccgg
     2041 cgcgctcttc ttcgagctcg gccagggtct tgtccatacg ctcgcggctg aaggcatcga
     2101 tttcgaggcc ttccacgcgg gtgtattcgc cgttcgcggt gatcaccggc acgccgtaca
     2161 tcacgccttc ggggatgccg tagctgccgt cggacggcac gcccatggtc acccacttgc
     2221 cattgctgcc gagcacccag tcgcggatgt ggtcgatcgc ggcgttggcc gccgaagctg
     2281 ccgaggacag gccgcgcgct tcgatgatcg ccgcgccgcg cttgccgacg gtcgggatga
     2341 agctgtcggc gttccaggcg gcgtcgttga tcttgtcctt cagcgacacg ccgccggcct
     2401 tggcgaagcg gtagtccggg tacatggtcg ggctgtggtt gccccacacg atcaggctgt
     2461 cgatgtcgcc cacggcgacg ccggccttgg cggccagctg gctcagcgcg cggttgtggt
     2521 ccaggcgcag catggcggtg aagttcttcg ccggcaggtc cggagccgac ttcatcgcga
     2581 tgtaggcgtt ggtgttggcc gggttgccga ccaccagcac cttgacgtcg cgcgaagcga
     2641 ccttgttcag cgccgcgccc tgggcggtga agatcttggc gttttccagc agcaggtcct
     2701 tacgctccat gcccgggccg cgcggacgcg cgccgaccag cagggccacg tcgacgtcct
     2761 tgaacgcgac ttcggcgtcg tcggtgccga tcacgccggc cagcagcggg aacgcgcagt
     2821 cctcgagctc catgatcacg cccttgagcg cggcctgggc cttttcgagc ggcagttcga
     2881 gcaactgcag gatgacgggc tggtccttgc cgagcatttc gccggaggcg atgcggaaca
     2941 gcagcgagta gccgatctgg ccggcagcac cggtgacggc aacgcggacg ggggtcttca
     3001 tcggggtgtt tccttcgcta gttgatcgat ggtgcgggcg cggagcccgc caaggtgatc
     3061 gtgaataagg gtggaaagcg tcgggcgctt tcgcagtcga tagcagcgcc aggcgcgttc
     3121 agagtcgata gcccagcggt ttcagccggt ctttgatctc gtccatgtcg tagccgtaga
     3181 cgatctcctg gccgacgatc gtcaccggca cgcctcgcgc gccgaccgcg ctcatggcgc
     3241 gctggccggc gggcgtgtcg atgtcgatga tgctgtagcg cacgtcggcg agttcgaaat
     3301 ccttgcgcag cttttcgcaa tagccgcacc actccgcggc cagcatcacg atgcgcttgt
     3361 cgccggtctg gtgacgcggg tcgtcgggtt tcagttcggc ctggcgagtg gcgaaccagg
     3421 cggtatcgcc cttgtaggcc agcgcatacg cgccaccggc cagacccagg atcagcagga
     3481 cggtgagtac gcgcatgcga ggctttcctt ggctacgtca gtgatgggac tgcgccgggc
     3541 tcagacgagc tcggcgaaga actcctggaa ccgctgcagg cccggagcga gctgcggcgt
     3601 cgggcaggtg tagctgatgc gcaacgcgcg cggctcgccg aacgccgaac ccggcacgca
     3661 ggcgacgccc ttggtttcca gcagcgcgct gcagaaatcc atgtcgttgc cgatcttcag
     3721 gccgctcggc acatgggtct tgccgaaggc gacgctgatg tccgggaaca cgtagaacgc
     3781 gccctgcgga cgcgggcaga ccacgcccgg aatggcgttc atcaccgcca tgacctggtc
     3841 gcgcttggcc tggaactcgg cgcatttctg cgtcggcacg tcctgcgggc ccgacagcgc
     3901 ggcgaccgcg gcggcggtga cgacttccgg cacgttggtg atgtggttgg agttcatcgt
     3961 ggtcacggcc tgggcgaccg attccggccc ggccatgaag cccacgcgcc aacccggcat
     4021 gccgtaggtc ttggacagcg agtcgatgaa gatcacgcgg tcgcgcagtt ccggacgggc
     4081 atggacgaag ttgtggtagc ccaggccgtc gaacaccatg cggttgtaga tgtcgtcggt
     4141 gatgatccag gtgtccggat acttcgccac gacgtcggcc agcgcgtcga tttcttcctt
     4201 cccgtagacc atgccggtcg ggttggacgg gttattgaac aagaacacct tcggcttctt
     4261 cgccagtgcg gcgtcgagct gcgcgggggt gagcttgtag tcctgcgaag ccgggcacgg
     4321 cagcaggtcg atctgggcgt tgacgatctc ggcgatgtcg agatagctgg tccagtacgg
     4381 ggtcgggaac gcgatcgtgt cgccttcgtc gagcagcgct tcggcgatgt tgtagatcac
     4441 gtgcttggcg ccgatgccgg tggcgacgtt gacgcggccg tagccggtca gaccgatctt
     4501 gcccatgtgc tcgatgaagg catccagcaa tgcgtcggcg ccgcggttgc tgccgtactg
     4561 gccgctgtct ttggccagcg cgtcgcgcac ggcggcgtag acatggtcgc cgggcagaaa
     4621 gttgggaacg ccgatcgaaa agctgatgat gtcgcggcct tcggctttga gccgcttggc
     4681 cttttcggca acctgcatga tcgcgctggg cttggcgcga ccgatgcgcc gggcgagctg
     4741 gggcatcgtc ttgaacctcg tggggtggtg tacgacggag ctggtgcggg agaggagcgt
     4801 gcgcgagacg gcagtggcgg cgcgccggcg tgcccggcag ctgaagagca gtgctcgggg
     4861 aacgcctgcc ggaaccactg gttcgagccg caaaatggta gcacagcgtc gccgccacgc
     4921 cggcttcgac tacgcctgtt tacgcgcccg gatcggcgtc ttcgccgccg ttcgcggtgc
     4981 ccgatcggcc gcgccgcttt gcccgggcgg ccgcttcggc gcggccctgg cgtcgccgcc
     5041 gcgacgaatg ccggcggcgg cgctgcagaa acgaaaagac ggccttgcgg ccgtctttcc
     5101 tgtcccgcct tggagagggc cgcggcggtg gccgccgcgg cccgcagctt caggcgcggg
     5161 cgttctcgtc gaggaccttg ttccagtcgg cgacgcgctc ggccttggcg gccagggcgc
     5221 cggcgacatc gccttcgatc ttgaccgact tgatcttgtc gccctgcttg accgcatcga
     5281 ccacgtccag gccttcgagg accttgccga acacggtgtg cttgccgtcg agccagtcgc
     5341 agacgatgtg ggtgatgaag aactggctgc cgttggtgcc cgggccggcg ttcgccatcg
     5401 acagcacgcc gcgctggtgg cccaggccgt tacgggtctc gtcttcgaaa cggtagcccg
     5461 ggccgccggt gccggtgccc tgcgggcagc cgccctggat catgaagttc gggatcacgc
     5521 ggtggaagtt caggccgtcg tagaagccgc gctgggccag attgacgaag ttggcgacgg
     5581 tcagcggcgc cttgtcggcg gcgagttcga cgcggatcgg gccgcggtcg gtgtcgaaag
     5641 tggcgatcag gctcatacag cggactccag atggtgcgag gggatgggac aacggacgtt
     5701 cggcagccga catggcggcg cccggggcca tccacaaggg tacccgatgg gcgattcggc
     5761 cggcccgccg ccccctggct cggcttgggg cggtcagcag ggaactgcgg gaaatccggc
     5821 gccgacggcc tccgccgcgc agcctgccgg cccggatcgc cctgccccgt tcataaaact
     5881 ggcccgcagg cgaataaatc ctcgccccgc aggcacttgc catctttgcc cgctataatg
     5941 atcggcttac ttcctcagct atagcgcctt ccggcgtcca atcgcatgtc catcgaacgc
     6001 ctgcgcaata tcgccatcgt cgcccacgtc gaccatggca agaccaccct cgtcgactgc
     6061 ctgctcaagc agtcgggcac cctgtccgaa cgcacggtgc tggccgagcg cgcgatggac
     6121 agcaacgacc aggaaaagga acgtggcatc acgatcctgg ccaagaacac cgccatcacc
     6181 tggcagggca accgcatcaa catcgtcgac accccaggcc acgccgactt cggcggcgag
     6241 gtcgagcgcg tgctgtcgat ggtcgactcg gtgctgatcc tggtcgacgc gatggacggc
     6301 ccgatgccgc agacgcgctt cgttacccag aaggccttcg cgatgggctt caagccgatc
     6361 gtcgtggtca acaagatcga ccgcccgggc gcccgtccgg actgggtcat cgaccaggtg
     6421 ttcgacctgt tcgacaagct cggcgccacc aacgagcagc tcgacttccc gatcgtgtac
     6481 gcctcggcgc tgcacggcta cgccagcctc gacgacgctg cgcgctcggg cgacatgacc
     6541 ccgctgtacg aagcgatcat gaagcacgtg gcgccgccgc aggtcgacct cgacggcccg
     6601 ttccagatgc gcatcagcca gctggactac agcaacttcg tcggcctgat cggcatcggc
     6661 cgcatccagc gcggcaaggt ccgccgcaac atgccggtca gcgtggtcga ccgtaacggc
     6721 aagaagcgcc agggcaaggt cctgcaggtg ctcggcttca tgggcctgga gcgtctggag
     6781 accgaggaag ccgaggccgg cgacatcgtc gccatctccg gcgtcgccga gctgtcgatc
     6841 tccgacaccg tgtgcgcgct cgacaccccg gaagccctgc ccgccctgac ggtggacgag
     6901 ccgaccatca gcatgacctt ccaggtgaac aactcgccgt tcgccggcaa taaagagctc
     6961 agcggcggca agttcctcac cagccgccag ctgcgcgagc gcctggagcg cgagacgctg
     7021 cataacgtgg cgctgaaggt cgaagaaggt tccgacccgg acaagttcct ggtgtcgggc
     7081 cgcggcgagc tgcacctgtc ggtgctgatc gagaacatgc gtcgcgaagg cttcgagctg
     7141 gccgtgtcgc gtccggaagt gatcatcaag gaaatcgacg gccagcagat ggagccggtc
     7201 gagcagttgg tggtcgacat cgaagagcag caccagggcg gcgtcatgga gaagctcggc
     7261 acccgcaagg cccagctcaa gaacatggag cccgacggca agggccgcgt gcgcctggat
     7321 tacatgatcc cggcgcgcgg cctgatcggc ttccagaacg agttccgcac cctgacccag
     7381 ggttcgggcc tgctgttcca cgtgttcgac cattacggcc cgaaggaaca gggcgcgatc
     7441 gccaagcgca tcaacggcgt gatgatcgcc aatgcgccgg gcgccacccc ggcctattcg
     7501 ctgggcccgc tgcaggagcg cggccgcctg ttcgccgccg agggcgacaa cgtctacgag
     7561 ggccagctga tcggtatcca ctccaaggac aacgatctga ccgtcaacgc catcaagacc
     7621 aagccgctga ccaacatgcg cgcttcgggt aaggacgatg cgatccagct cagcccggcg
     7681 atcaagtaca cgctggaaca ggcgctggac ttcatcgagg acgacgagct ggtcgaagtc
     7741 accccgaagg aaatccgcct gcgcaagaag ttcctcaccg aaagcgatcg caagcgcgcc
     7801 tcgcgcgcgg cctgatcggc accaccgtcg ccttgtccgc aaggcggcat cgccccaacg
     7861 ctctcccgcc cgcgggagag cgttggggcc aaggaacgcg cgccgatggc gcgcgttccg
     7921 gtttctacgg cccataccgg cacagtcgac ggccatgctc gacggcgcag gccgggaacc
     7981 ctgacgcgca accgggatcg aacgccgcat gtccatgcac gatctgatca tgtccgcttc
     8041 tatccggttc gaccctatcc ggttcgatcc tatccggttc gatccaatcc ggttcgatcc
     8101 aagcccgttc gattcctgcc ggttcgcgtc gaaccgacac gcacggcctc gcctgcaatc
     8161 cgcatccggc gcaccgcgat gacgccgacc gatcccgatt acgacagcga ccccaaggct
     8221 catccgggtc tgcacctgat cgccgcggtc gaagcgatca agggcctgct cgccctgtcg
     8281 gccgcgagcg ggctggaact gctcggcccg gcgccgttgc agcgctggat cgaagaactc
     8341 atcaaacgct tccatctcga ccccgagcac ggctcgctgg cctggctcgc gcaggcgatc
     8401 agcccgcact cggtgcacct ggccgccggc gtcgtgctcg cctacggcct actgcacctg
     8461 atcgaagcct ggggtctgtg gaaggcgaag gcctgggcct cgtggctcgg ctgtatcggc
     8521 gcggcgctgt atctgccgtt cgatctctat gccttgtatc gccatcccgg ctggctggcc
     8581 attgcagttc tcataatcaa cgtgatcgtg gtttgggttc tcggccgcga cctgttcaag
     8641 cgccgtcgct gaggcctgcc tgctcggttc ggcggcaggg ccgcggcgca ccggagcgta
     8701 ttgcccgcat cgcgatcggg ctcgaaatca caggcgccgc ccatcgagcg ggtgtatcgt
     8761 tttgaggtcg cggccccggc ccgaccgcaa gccgcggcct ccgcatcccg gcttgcgcga
     8821 tgcaaggccg tgcggacgcg cgcaagccat cgcccgcggc tccaccgtcc cggcaaggcc
     8881 ccactcccca acgcgaggaa cgtacatgaa gacctggtcc aagcctcaga tccgcgaaat
     8941 ctcggtcggc tgcgaaatca attcgtactc ctccggcgac ctgttctgaa tcatgcccgc
     9001 ttccgccgtc gcaacgcgcg cgagtcgtaa cgctggcccg atggcgacac gatgatgcat
     9061 atcgtcgtgc tcggtgcggc ggccggaggc ggttacccgc agtggaattg caacaccccc
     9121 ggcagccggc gcgcctggcg ccaggagccc ggccataagc gccgcagtca ggccagcatc
     9181 gcggtcagcg ccgatggcga acgctggttg ttgatcaacg cctcgcccga tttccgccag
     9241 caggtgctgg ccattccgcg gctgtggccg cagcgcggcc tgcgccattc gccgatcgag
     9301 gcggtgctgc tgaccagcgg cgagatcgac cacatcgccg gcctgctgtc gatgcgcgaa
     9361 cgccagcgct tcgacctgtg ggccagcgcg cgcgtgctgc agctgctgcg cgataacgcg
     9421 atcttcgacg cgctcgatcc cgagtacgta acgcgcagag cgctgacgct cgatgcgccg
     9481 ctcgatgtcg ccggcctcga cgctccgttc ggtctgcgcg tgaccgcgtt cagcgtgccc
     9541 ggcaaggtgc ccttattcat ggaatcgcgc agcggcggcg acctcgccgg ctcggccgag
     9601 gaaactgtcg gcctggagat ctccgacggc agccaacgct gtttctatat tcccggctgc
     9661 gcggcgatga cgccggcctt gcgcgaacgc ctgcgcggcg cggcactggt gttcttcgac
     9721 ggcaccctgt ggcgcgacga cgagctgatc cgcgccgagg tcgggcacaa gaccggtgcg
     9781 cgcatgggcc atatgaacat cctcggccaa ggcgagggcg acgccggcgg caccctcgcc
     9841 gcgttcgccg acctcgacgt gcagcgcaag ctcttcatcc atctcaacac caccaacccg
     9901 gtgctcgacg aggcctctcc cgaacgcgcg cacgtcgccg cgcacggctg ggaagtcgcc
     9961 gaggacggca tggagatcag gctttgatgg agatcaggct atgaacgcgc acgccgtcga
    10021 agcggacccg tccgagcagc gcatcgccga cgatgcgctg ctgactccgg cgcaactcga
    10081 agcgcgcctg cgcgcgatcg gcgccgagcg ttatcacgac aagcatccct tccatgcgct
    10141 gctgcacagc ggccgcctca accgcggcca ggtccaggcc tgggcgctca accggttcga
    10201 gtaccagcgc tgcatcccgc tcaaggacgc cgccctgctc gcccgcatcg aagaccccga
    10261 cctgcgccgc atctggcgcc agcgcatcgt cgatcacgac ggcgaacgcg ccggcgacgg
    10321 cggcatcgcg cgttggctgc acctcaccga tgcgctcggc ctcgaccgcg acttggtcga
    10381 gtcgggtcgc ggcctgctgc cggcgacgcg tttcgcggtc caggcctata tccacttcgt
    10441 ccgcgaacgc agcctgctcg aagccatcgc ctcgtcgctg accgaactgt tcgcaccgaa
    10501 catcatcggc cagcgcgtcg ccggcatgct cgcccactac gacttcgtat cgaagccggc
    10561 gttggcctat ttcgactcgc gcctgcacca ggcgccgcag gatgcccact tcgccctcga
    10621 ctacgtcaaa cagcatgccc gcagccgcga gcagcaggac gcggtctgcg cggcgctgcg
    10681 cttcaagtgc gaggtgctgt ggtcgatgct cgatgccctc tacctcgcct atgtcggcaa
    10741 tgcgccaggc gagggccgca tcgacatgat cccgccgggc gcattccgcc cggacccgga
    10801 gcccggcgca tgagcgcgac gatcgatgcc cgcgcggtgc cgcgcttccc ggcgggcgtg
    10861 cgcctgcaac acgaccgcgc gcgcgaacaa tgggtgctgc tggcgcccga acgcgtggtc
    10921 gaactcgacg agatcgccca cgccgtgctc gcgcgcgtcg acggcaccgc cgacatcgcc
    10981 gcgatcgtcg acgcgctcgc ggccgagtac ggcgccgatg ccgaacaggt ccgcggcgac
    11041 gtgctcgaac tgttcgccaa cctgctcgac aagcgcatgc tcgcggtcgc agcgccggcc
    11101 tcatgaccgc ggcgacgcca tcgccgacac cggctgccgc ggtggcgccg ccactgcgcg
    11161 ccgaacgcgt accggcaccg ccgctcgcgg tactgctaga actcacccat cgctgcccgc
    11221 tgtcctgtcc ctattgctcc aatccgctgc aactggtcgg tctgcgcgat gagctggcga
    11281 ccgccgactg gctgcgcgtg ctcggcgaag ccgccgaact cggcgtgctg caggtgcact
    11341 tctccggcgg cgagccgacc ctgcgcaagg acttgcccga actgctgcaa cacgcgcgtt
    11401 cgctgggcct gtactgcaac ctgatcacct ccggggtcgg cgtcgagcgc gaacgtctgc
    11461 tcgccctgca acaggccggc ctggatcatc tgcaactgag catccaggac agcgaggaac
    11521 gcggcgccga ccgcatcgcc gggtatgccg gcagccatcg gcgcaagctc gccctggcgc
    11581 gctggtgcgg cgaactgggc ctaccgctga ccctcaatgc agtggtccat cgccacaacg
    11641 ccgaacgcgt cgcggcgatg atcgaactcg cgctcgatct cggtgccggc cggctcgaag
    11701 tcgcccacac ccagtactac ggttggggcc tgaagaaccg cgccgcgctg atgccgaccc
    11761 gggcgcagct cgacgccgtc accgccgtgg tcgaggacgc gcgcctgcgc ctgcgcggca
    11821 ccctgaccat cgactacgtc acccccgact attacgcgcg ccgccccaag gcctgcatgg
    11881 gcggctgggc gcagcgcttc gtcaacatca ccccggaagg caaggtcctg ccctgccatg
    11941 ccgccgagac catcgccgac ctgcatttcg attcggtgcg cgaacgcggc ctcggcgaga
    12001 tctggcgcga gtcggacgcc ttccagcgtt atcgcggcac cgactggatg ccggaaccct
    12061 gccgcggctg tgagcgccgc gagatcgact ggggcggctg ccgttgccag gcgctggccc
    12121 tgagcggacg cgccgacacc ctggacccgg tctgcgatcg ctcgcccgac cacgccggcg
    12181 tgcgcgaact ggccgagcgc gaatcgcagg cgccggcgcc ggaattcgtc tatcgcaaga
    12241 tccggcccgc gggcaaccgc gcgccctgag cctcgccagg gcgcgacacg cgcacgttgc
    12301 gcttagaacg accgccatcc gaccgaacgg cgacctgcac cgtacaagcg gaacagtgtg
    12361 cctcgcccac ccaggtccgc gcgggcatac tcggccgact ccccgcagga atccgccatg
    12421 tccgccacgc ccgcgctgcg cctgagcgcc gtcgcgctcg tcctggccgt cgccggctgc
    12481 gcgagcagcg gcacgccgcg cccgacccgc ccggccgtgc cggccgacct gccgcgcggt
    12541 ttcctgcccg ccgacccgct gcgcctcacc gaaaccgaca gcgcgaccct ggccgcacgc
    12601 atggccgcgg gcgacttcag cagctccaaa ctgacccagg cctacctcga ccgcatcgcc
    12661 gcgctcgacg acgacgggcc gaggctcaat gcggtgatcg aactcaaccc gaacgctctg
    12721 gccgaggcgc gcgcactcga cgaagaacgc aaggccggca aattgcgcgg cccgctgcac
    12781 ggcatcgcgg tgctgatcaa ggacaacatc gatgccacgc cgatggtcaa ttcggccggc
    12841 tcgctggcct tggccgcgca ccgcccgcgg caggacgcgc cgctggtcgc cgcgctgcgc
    12901 caggccggcg cggtgatcct cggcaagacc aacctcagcg agtgggccaa ctttcgctcg
    12961 acccgctcga tctccggctg gagcggccgt ggcggcctga cccgcaatcc ctacgcgctc
    13021 gaccgcaccg cctgcggctc cagcagcggc accggcgccg ccatcgccgc cagtctggcc
    13081 accctcggcg tcggcaccga aaccgacggc agcatcctgt gcccggcggc catgaacggt
    13141 ctggtcggct tcaagcccag cgtcggcctg gtcagccgcg ccggcatcat cccgatctcg
    13201 cacagccagg acagcgccgg cccgatggcg cgcaacgtca ccgatgccgc gcgactgctg
    13261 agcgtgctcg ccgcggccga cgccggcggc gacgccgccg cgcaggccgc cgccggcaaa
    13321 cgcatcgacg actacgtcgc gacgctcgat gccgagtcgt tgcgcggcgc ccgcctgggt
    13381 ttcatccgcg acgccggggt caagacgcct ccatcgatcg acgcggtgct cgaacgcacc
    13441 ttcaagggca tgcgcgatgc cggcgcgacc atcgtcgagg tgcgcatgcc gaccgccggg
    13501 caatgggacg cggccgagtt ccaggtgctg ctgtacgaat tcaaggacgg cgtcgagcgc
    13561 tacctgcgcg aacacgatgc gccggtcaaa acgctgagcg agctgatcgc tttcaaccgc
    13621 gccaacgccg ccaccgagat gccttacttc gaccaggaac tgctcgaaca ggccaacaag
    13681 aaaggcagcc tcaaagacgc ggcctatcgc aaggccgcgg cccgcgcgcg ccagctcgcc
    13741 ggtgcccagg gcatcgatgc ggtgatgaag cggcacaagc tcgacgccct gatcgcggtg
    13801 gcgacgaccc cggccttcat ggtcgacgcg gtcaacggcg accccttcgg cggcgccagt
    13861 tggggcgcgg ccgcggtggc cggctacccg agcctgaccg tgccgctggg cgaagcctcg
    13921 ggtctgccgg tcggcatggt cttcatgggc cggcgctgga gcgatgcgaa gctgttgtcg
    13981 ctgggttatg ccttcgagca actgacccag gcgcgcaccg caccgcgcta tcgggcgacg
    14041 ttgaatccct gagctgcaag cggcggcgga gacgctgagc tcgctcgctt tgtcgacgcc
    14101 ccacggcctc gattcgcgag cgatcaatcg cgcaggaagg ccgcggtcgt cgaccacagc
    14161 gccgtgcgcc gcggttgcag atgcagccaa tgattgccgc ctgaaatctt gacgtcgcgc
    14221 cgctccgacg ccccgctgag ttcggcgtac agtcgcgcgg catcggcatc ggtggtgacg
    14281 tggtcccact cgccgcgaac gatcaaagtc ggctgacgca ggcgcgtatt gtcgaccaag
    14341 gcttgcccgg cccagagccg gtcgatatcg gccatcggcc cggtcggaat ccgtaccgac
    14401 ggcgggttgc gcgtggccga cgcttcatcg ctggccagat acgcccggca ccagcgctcc
    14461 agctcttgcg cacctaccgg cgtggccgcg tccgcgggca gccccgagcg ctggcgcggc
    14521 cgttgatcgg ccgcgccgat cagcgtccag gccggcttag gctcattgcc tggagggcct
    14581 tcgcgagtcg aaaccggccc gaacaacacc agcttgctca ccgcgtcggg atgctcgatc
    14641 gccgcttgcc gcgccggcaa cgtgccccag gaatgcgcga gcagatggat cggcgcgtgc
    14701 gggcgctcgc gccggatcgc ggcgatggcg gcggcgatct gcgccgcgcc catgcggtag
    14761 tcgccccagg gcggcgccga gtccgcagcg gcgcggaaca cctcgggccg ctgcgagtag
    14821 ccgtatccgg cgaaatccag cccccaggca tcgaagccct gcgcctgcag atggtccagc
    14881 cacgacctgc cgtccatgcg ccagccgatc gatagctcgc agggaaacgt ggcgccgtga
    14941 acgtacagca cgaccgggcc ggtacccggc tcccgcacga gcgacaatcg caagatttca
    15001 ccatccaagg cgcatgcggc cgagcgtcgt tcgcgcgcag accgatcgcc cgctgccatc
    15061 gccggcagcg gcaacatcga caacgccatc gcggatagcg gccaggtcat cagatcgcgt
    15121 cgtttcatcg cagccatcgc ataggaagat ggcgcgattg tgcgcatcgc atcgtcggaa
    15181 cgattcggcc ggcagcgaag cgtaaggttg ccgttgccgt tgccgtaaag agcttggcga
    15241 aatttcgaac tagcgatgcg atcgtagacc cggagggcgg cgcacaggac gtgcgccgtt
    15301 ttccgataag acagggacgt cttatcggaa aatcccggcg cgggctgcgt gctcgcaggg
    15361 gagcttcgtc aaggaaaagc acttttcttt ggtgactttc ttttggggct ttggccaaaa
    15421 gaaagttacc cgcacccttt agggggcgga agctctgcac ttgcttgagc cacgcagtac
    15481 cgcgatccac ccctgtagga gcgacataag tcgcgactgc gacgcatcaa tctcgcgccg
    15541 ctaccaaccg cagcccgtca gggtaggagc ggcgtcctac tggatttcct tcggtcacaa
    15601 gccgcgacca cgccgtcgca gtctcgcggc gcatctttaa agcaagatcc agatcaaacg
    15661 ccaaaagctt ccgccactaa agcggcgggt tactttcttt tgtcataagc aacaaaagaa
    15721 aggtaaccaa agaaaaatgc ttttctttga atcacaggcc cgcgcgcgcg gtgcgtccgc
    15781 agggattttt catacgggac atccctgtcc cgatgaaaaa cggcgcgcat ccatgcgcgc
    15841 cgccctccgg gtcttcgatt gccttcgcta gtacgaggct acgcacagca acggcaacgg
    15901 caacggcacc ggcgccggcg ccggcaatct ccccttgtgc gccacgtcgc ggacatctct
    15961 ccatccaccg ccacatcgcc aaacaaaaag cccgccttgc ggcgggcttt tgtcttgcgg
    16021 tggatcgacc gaacctgaag cgaaatctca ggccggcgcg gcgatctgcg cttgcttgcg
    16081 cacgatcagc atcgccactt ccagcgcctg ctcgtagttc aggcgcgggt cgaccgtgga
    16141 gcgataggcg cggtcgagat cgctctcggt cagttcgcgc gcgccgccca ggcattcggt
    16201 cacgtcttcg ccggtcagct ccaggtgcac gccgcccatg cgcgttccgg ccgccgcgtg
    16261 cagctcgaac gaggtctcga tctcggcacg gatgttgcgg aaacgacggg tcttgtagcc
    16321 gttgctggtg ctctcggtgt tgccgtgcat cgggtcgcag acccacagca cgcgacggcc
    16381 gtcgcgacgc atcgcgtcga gcagcggcgg cagcttctcg gcgatgtggc tcgcgcccat
    16441 gcggtggatg aaggtcaggc ggcccggctc gtcctcgggg ttgagcaggt cgatcgtgcg
    16501 cagcagttgg tccggcgtca ccgacggacc gaccttgagc gcgatcgggt tgcggatgcc
    16561 gcggaagtat tcggcgtggg cgccgtcgac cgctgcggtg cgcatgccga tccacgggta
    16621 atgggtgctg agattgaaga agccccagtg acgtggcacc tgccgggtca acgactcttc
    16681 gtacggcagc agcaaggctt cgtgcgaggt gtagaagtcg acgcggttga ggttgtgcac
    16741 ctcggaaccc gacagcgtct ccatgaagcg caccgcatcg ccgatggcgt tgaccatgcg
    16801 ccggtactcg tcggccagcg gcgagtggcc gacccagctc aggttccagt actcgggatg
    16861 gtgcaggtcg gcgaaaccgc cgtcgatcag ggcgcggacg aagttcatcg tcatcgccga
    16921 acgcgcatgc gccttgatca tgcggcgcgg gtcgggcttg cgcgcggcct cgttgaaggc
    16981 cggcgcgttg accatgtcgc cgcggtagct cggcagggtc accccgtcga tggtctcggt
    17041 gtcggccgaa cgcggcttgg cgtactggcc ggcgaagcgg ccgacacgca cgaccggctt
    17101 gcgcatgccg tgcacgagca ccaggctcat ctgcagcagc accttcaggc ggttggagat
    17161 cacgtccgag gagcactggt cgaagctctc ggcgcaatcg ccgccctgca gcaggaagcg
    17221 cttgccttcc tgcgcctcgg cgagctgctg cttgagcgag aggatctccc acgaagtcac
    17281 cagcggcggc agatgacgca gttcctgcaa cgcggattcc aactcggccg cgtccggata
    17341 attcggcaac tgcagtgcgg tgcgctcgcg ccaggacgtc ggcgtccagt cggcgggaag
    17401 gttgacggca cgcaggttgc gatcggaggc gctcatttcc ttggtttcca gttggggaca
    17461 gcggtgggga tcgagtgagg cggggactct attgaatcaa cgacggcgga acgcggcata
    17521 ggccgcccag accgccagga ctatgaagca gatcaggctc caggccggca tggccaggcc
    17581 gaggaagctc cagtcgaccg cggcgcattc gccggaaccg gtcatgacct tgcggatcac
    17641 cccggcgatc ggcatcgcat cgagcatgta gtccagcccc gggccgcagg ccgggacctg
    17701 gtccggcggc aggtgctgca gacgtacgtg gttgccggcg acggcgatgc cggcgagcga
    17761 ggccagcagg gccagcacgc cgtagctgcg gcgtccgccg gcctttttcg ggccatgcag
    17821 ggcgccggcc aggaatacca ggccgagggc gaagaaggcg acgcgctgga agatgcacag
    17881 cgggcagggt tcgaggtgct ggtacagctg caggtagaac gcgtacgcaa gcaggcccgt
    17941 gcaggccagg aagccgagca ggtactgggt ccggaaagag gctttgaagg ggttcatgtt
    18001 cacaccatac gggtctgggt cgggtcgtgc caatgtcgga taggcatgtc gctacgcaac
    18061 gtggcgtttc gtcgcagcaa catcgactgc gccgggccgg aaaagttgcg tcgcgaaacc
    18121 gattgcccct cgaaacccgt ctcccataat cattaccgcc gcaaccgttg ccgaagtaac
    18181 cgtcgccgaa aagcaaaaac cccggccggg gccggggctt cgctagctgg gcgagcgacc
    18241 atcgccggtc gcctgcctgg ggcttgcatg tcgtatcgca gcgccggtcg cccggcgccg
    18301 gcgatcactc ggccgcggct tgcggacgat cgaccagttc gacgtaggcc atcggcgcat
    18361 tgtcgccagc gcggaaaccg cacttgagga tgcgcaggta accgcccgga cgcgaggcgt
    18421 aacgcgggcc gagttcgacg aacaaggtgc cgacggcttc cttgtcgcgc aggcgcgaga
    18481 aggccaggcg gcggttggcg acgccgtcct tcttggcgag ggtgatgagc ggctcggcaa
    18541 cgcgacgcag ctccttcgcc ttcggcaggg tggtgcggat gagaccgtgc ttgatcagcg
    18601 aagcggccat gttggtgaac atggcgtcgc ggtgagcact ggtgcggctg aacttacggc
    18661 cggatttctg gtggcgcatg gttgggattc ctgatgaatg tcgtaactgt tggagatcgc
    18721 tgtcgccatc caggcgttgg agcattggac tgcggttggt ccgaaccggc cttccctgac
    18781 cggcgagccg cggacttaag gtccgtcggc gtgtgttgcg gtgttgctct tactgagttg
    18841 cctgaatcag aaatccacgc ttcggctgag cttcggcgtg gatttctttt cgttccccgg
    18901 ccctgcgcag cgcgccgggc cttcgcccaa gccgcgcggc agtgccgcgc gggctaggct
    18961 tgggtttagc ccatcatccc gtgcgaggcg atgccggccg gcggccagtt ttccagcttc
    19021 atgccgaggg acaggccgcg ctgagccagt acttccttga tctcggtgag cgacttcttg
    19081 ccgaggttcg gggtcttgag cagctcgact tcggtcttct ggatcagatc gccgacgtag
    19141 tagatgctct cggccttgag gcagttggcc gaacgaacgg tcagctcgag gtcgtcgatc
    19201 ggacgcagca ggatcggatc gatgccgctg gtggccggct tctgcgcacc gcggtcgcgg
    19261 tgggtgaagt cgccgaacac cgacagctga tcggtgagga tgtcggcggc ggtgcgcacg
    19321 gcttcctcgg cgtcgatcgt gccgttggtt tcgatgtcga gcacgagctt gtcgaggtcg
    19381 gtgcgctgtt cgacgcgcgc ggcttccacc gcgtaggcga cgcgacggac cggcgagaag
    19441 ctggcgtcga gcatcaggcg gccgatcgca cgggtttctt cgtccggacg acggcgcgaa
    19501 gccgccggct ggtagccgaa gccgcgttcg atcttcagac gcatgttgag tgccgtgtcc
    19561 ttggtcaggt ggcagatcac atggtcggtg ttgaggattt cgacgttgtg gtcggtcttg
    19621 atgtcgccgg cggtgacgat gccgggaccc tgcttggcca gcgacagcgt cgaagcgtcg
    19681 ccggtgtgca tgcggatcgc gacgtccttg aggttcagca gaacctccag cacatcttct
    19741 tccagacctt cgaccgtggt gtactcatgc aacacgccgt cgatttcgac ctcggtgatg
    19801 gcgaaacccg ggatcgaaga cagcagcacg cgacgcagcg cgttgcccag cgtgtggccg
    19861 taaccgcgct ccaacggctc gatcacgact ttcgcgcgat tgccggtgag gcgttcgatc
    19921 tgcggaccgc gcgggcgcag tacctggttg gcggtaaccg tcatgtttcg gtgtctccaa
    19981 tgaccttcgt cggggggcga cggaaggctt tagctcttgg agccccctct agttcgaggg
    20041 agcggccgat gcgcctggcg catcgacctg ggttgcgggt actgccggcc ccgaggaacc
    20101 ggcagcgccc tgcactatta cttgctgtac aactcgacga tcagcgcttc gttgatgtcg
    20161 gccggcaggt ccgcacgatc cggaaccgcc ttgaacacgc cgctgaactt cttgttgtcg
    20221 acctcgaccc acgacggcga caggtccatc tgcgacgaca cggtcaggga ttcctgcacg
    20281 cgaagctgct tctgggcgcg ctcggacaac gcgatcgcgt cgccggcctt gacctggtac
    20341 gacgggaggt tgaccgactt gccattgacc gtgacgccac ggtgcgagac cagctggcgg
    20401 gcggccggac gggtcacggc gaagcccatg cggtagacga cgttgtcgag acgggtctcc
    20461 agcaactgca gcaggttctc gccggtgttg cccttcttgg tcgaggcctt cttgtagtag
    20521 ttgcggaact gacgttccag cagaccgtag atacgcttga ccttctgctt ctcgcgaagc
    20581 tgggtggcgt agtcggacag cttgcccttg cgggcggtgg ggccatgctg gccgggcttt
    20641 tgctcgagct tgcacttcga gtcgagcgcg cgagcggacg acttcagacc aaggtcggcg
    20701 ccttcgcgac gagcgagctt acaggtgggg ccaatataac gagccatttt tcttcagctc
    20761 ctcagacgcg acgctttttc ggcggacggc acccgttgtg cgggataggc gtcacgtcga
    20821 tgatgttgat gatcttgtat ccgacgttgt tcagcgaacg aacggcggac tcgcgacccg
    20881 gacccgggcc cttgatgcgc acttccaacg acttgacgcc gtagtcgagc gcagcacggc
    20941 cagccttttc ggctgccacc tgggcggcga acggggtcga cttgcgggaa ccgcggaaac
    21001 ccgcgccgcc cgaggtcgcc cacgagagcg cgttgccctg gcggtcggtg atcgtgatga
    21061 tggtgttgtt gaaagaagcg tggacgtggg cgatgccgtc ggtgacgact cgcttgatct
    21121 tcttcttggt tttggcagct gccggcttgg ccatggtatg ggtcccttac ttcttgatgg
    21181 ccttgcgcgg acccttacgg gtacgtgcat tggtacgcgt gcgctgacca cgcagcggca
    21241 agccgcggcg gtgacgcagg ccgcggtagc agcccaggtc catcaaacgc ttgatcgcaa
    21301 taccgacctc gcgacgcagg tcgccttcga ccacgaactt gccgacttcg gcgcgcaagc
    21361 gctcgacttc cggctcggac aggtcacgga ttttggtcgt cgaagtgacg cctgcggact
    21421 cgcagacttg cttcgaacgg gtacggccga tgccgaaaat gctttgcagg ccaacccaga
    21481 catgcttctg ggcaggcaaa ttaacgcccg caatacgcgc cataaggcga tctccaactg
    21541 atttggcggc caggacggat taatcccggc ggagtgaact ggaaattata tctaggtctc
    21601 gggttaatag gaagccccgc ggcaccaaag gtgccacgga accacggcat ggggagtgtg
    21661 cccatgctcc ggcgacgaat ctgaactggc tgaacaaggc ggtgacctgc cctcccagcc
    21721 ccgcgcgcta ctctggcgcg cggaacggtc ctgactcacc cgcgcgcgag accgccgcgc
    21781 gagccgccct tcaagttcgc tttcttcaac aggctttcgt actgatgcga catcagatga
    21841 gcctggattt gagcgatgaa atccatcacc acgaccacga cgatcagcaa cgaggtgccg
    21901 ccgaagtaga acgaggttcc cagttgggtc cgcatgacct ccggaaggag gcagacgatc
    21961 accaggtaaa ttgcgccagc cgccgtaaga cgagtcagca cgccgtcaac gtagtccgcg
    22021 gtggccttgc cgggacggat gcccgggatc agcgcgcccg acttcttgag gttgtcggcg
    22081 gtttcctgcg aattgaacac cagcgccgtg tagaagaacg cgaagccgat gatcaggcca
    22141 gcatacagga tcatgtgaac cggttcaccc gggttcaacc actggctgag gcgttgcagg
    22201 aagccggaga aaccgctgcc gctgttgttc tgggcgaacc aggtcgctgc cgtcgccggg
    22261 aacatcacg
//
