LOCUS       NZ_LMFT01000025        18680 bp    DNA     linear   CON 07-JUN-2024
DEFINITION  Streptomyces sp. Root55 contig_31, whole genome shotgun sequence.
ACCESSION   NZ_LMFT01000025
VERSION     NZ_LMFT01000025.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root55
  ORGANISM  Streptomyces sp. Root55
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 18680)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 18680)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140605
            Assembly Name                     :: Root55
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001427245.1-RS_2024_06_07
            Annotation Date                   :: 06/07/2024 01:50:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,084
            CDSs (total)                      :: 7,008
            Genes (coding)                    :: 6,730
            CDSs (with protein)               :: 6,730
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (5S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 278
            CDSs (without protein)            :: 278
            Pseudo Genes (ambiguous residues) :: 0 of 278
            Pseudo Genes (frameshifted)       :: 105 of 278
            Pseudo Genes (incomplete)         :: 225 of 278
            Pseudo Genes (internal stop)      :: 24 of 278
            Pseudo Genes (multiple problems)  :: 67 of 278
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:11:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 18680
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMFT01000025.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     source          1..18680
                     /collection_date="2012"
                     /country="Germany: Cologne"
                     /db_xref="taxon:1736554"
                     /host="Arabidopsis thaliana"
                     /isolation_source="root"
                     /lat_lon="50.958 N 6.856 E"
                     /mol_type="genomic DNA"
                     /organism="Streptomyces sp. Root55"
                     /strain="Root55"
                     /submitter_seqid="contig_31"
     region          1..18680
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..18680
                     /SMILES="C=CC=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18680
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[1306:11218](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1307..11218
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            247..>1219
                     /locus_tag="ASD51_RS38705"
                     /pseudo=""
     CDS             247..>1219
                     /NRPS_PKS="Domain: PKS_PP (1-83). E-value: 1.4e-28. Score:
                     91.1. Matches aSDomain:
                     nrpspksdomains_ASD51_RS38705_PKS_PP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012337.4"
                     /locus_tag="ASD51_RS38705"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="type I polyketide synthase"
                     /pseudo=""
                     /sec_met_domain="PP-binding (E-value: 4.6e-16, bitscore:
                     47.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 3e-46, bitscore: 146.4,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.8e-31, bitscore:
                     98.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPADRTRSVTGLTAAHIAAVLGHDKDNRPDARHSFKDLGFDSLM
                     SVELRDRLATATGLRLPGGLLFDHPTPAALTAYIEAELTGSATADEQHPATPLHDDEPI
                     AIIAMACRYPGGISSPEDLWRLVADGKDAISGFPADRGWEPDLYDQDPERSGKSSVHEG
                     GFLHDAALFDAAFFGISPREALAMDPQQRLLLGARRHRPGHPARQPHRRLRRSHRPRLR
                     PPPARSPHQRRRPPAHRLHQQRHVRTHRLPTGTRRPRPHHRHRLLLLPRRPPHRREVAA
                     PGRDDPRDRGRRDDHVRPRHVHGVLTAARPRRRRPQQILLRRR"
     aSDomain        250..495
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS38705_PKS_PP.1"
                     /evalue="1.40E-28"
                     /label="ASD51_RS38705_PKS_PP.1"
                     /locus_tag="ASD51_RS38705"
                     /protein_end="83"
                     /protein_start="1"
                     /score="91.1"
                     /tool="antismash"
                     /translation="SPADRTRSVTGLTAAHIAAVLGHDKDNRPDARHSFKDLGFDSLMS
                     VELRDRLATATGLRLPGGLLFDHPTPAALTAYIEAEL"
     gene            1307..11218
                     /locus_tag="ASD51_RS21760"
                     /old_locus_tag="ASD51_34140"
     CDS             1307..11218
                     /NRPS_PKS="Domain: PKS_AT (262-566). E-value: 1.5e-105.
                     Score: 344.8. Matches aSDomain:
                     nrpspksdomains_ASD51_RS21760_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (639-806). E-value: 1.4e-57.
                     Score: 186.7. Matches aSDomain:
                     nrpspksdomains_ASD51_RS21760_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1102-1281). E-value: 2e-60.
                     Score: 195.8. Matches aSDomain:
                     nrpspksdomains_ASD51_RS21760_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1378-1463). E-value: 7.4e-33.
                     Score: 104.7. Matches aSDomain:
                     nrpspksdomains_ASD51_RS21760_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1486-1910). E-value:
                     4e-182. Score: 597.8. Matches aSDomain:
                     nrpspksdomains_ASD51_RS21760_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (2019-2313). E-value: 1.2e-109.
                     Score: 358.2. Matches aSDomain:
                     nrpspksdomains_ASD51_RS21760_PKS_AT.2"
                     /NRPS_PKS="Domain: PKS_DH (2381-2544). E-value: 1.7e-56.
                     Score: 183.1. Matches aSDomain:
                     nrpspksdomains_ASD51_RS21760_PKS_DH.2"
                     /NRPS_PKS="Domain: PKS_KR (2865-3044). E-value: 3e-61.
                     Score: 198.5. Matches aSDomain:
                     nrpspksdomains_ASD51_RS21760_PKS_KR.2"
                     /NRPS_PKS="Domain: PKS_PP (3138-3224). E-value: 3.4e-34.
                     Score: 109.1. Matches aSDomain:
                     nrpspksdomains_ASD51_RS21760_PKS_PP.2"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (3233-3301). E-value:
                     1.5e-10. Score: 33.8. Matches aSDomain:
                     nrpspksdomains_ASD51_RS21760_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="ASD51_RS21760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_34140"
                     /product="type I polyketide synthase"
                     /protein_id="WP_348982821.1"
                     /sec_met_domain="PP-binding (E-value: 3e-18, bitscore:
                     54.7, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 3.4e-231, bitscore:
                     755.8, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 7.9e-91, bitscore:
                     292.5, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1e-110, bitscore: 358.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 5.9e-66, bitscore:
                     210.1, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRGSAVNQDGASNGLTAPNGPSQERVIRQALADARLTTADVDAV
                     EAHGTGTRLGDPIDKSNIGHAQAAAGVGGVIKMVQAIRHGVLPRTLHVTAPTPHVDWTT
                     GGLELLTEARAWPATDRARRAAVSAFGISGTNAHVIVEQPENDTPDRPDDTPAHPRDDT
                     TTGSRTPALWALSAPDRAALSAQAEALRTHLDDRPELGAQDIADIGFSLATSRATWPER
                     AVVTGTATAELLDGLDALRRTTDAPNLVTGSAARAGRTAFLFTGQGSQYPGMGRELYES
                     RSEFATALDEVCAALDPHLDLGRPLRDVMFTDTGTGTDTGTDADAGGSGAALLHETRAT
                     QPALFALEVALHRTLQAHGLVPDAVAGHSIGELAAAHVAGVLSLDDAATLVAARGRLMQ
                     AAVPGGAMLAIQAAESEVAETLTPYAGRLTLAAVNGPDAVVISGDADAADTLAALWRER
                     GRRTRRLTVSHAFHSPHMDTILDEFRTVAEGLTYHAPLLQVVSTLTGRPATGDDLVTPD
                     YWVRQIREAVRFLDATRTLEDEGVTVFVEVGPDAVLTAMADGAFLAGTSQAVALQRAGR
                     PQGTALTTGLARAHTLGAPLDLASLFPGASRVELPTYAFRRSHYWLRPRTRTDARGLGL
                     DPAGHPLLATTVDLAEGEGLVLTSSLSLTDHPWLADHRIHGTVLVPATAFIELASAAGR
                     TAGTEHLLELTLEAPLALPEQRPVRVQVAVSAPDTTGTRSFTVHSRPETDDEQTTWTRH
                     VSGALADTPATTDPAFDELLEWPPRDAEAVPPDDTYGQLTDLGYEYGTAFQGLRALWRG
                     RNGTTYADIALPADQHEAAAGYGIHPALLDAALHPVVLDTADTTEPDTIRLPFAWSGVT
                     THAVGATTLRVRIRHTGPDTVALHLADATGAPVATIDSLMLRPVAKDRLAPAATTDGLF
                     TLAWPSLAPPGGPAPRIAELPAGTDAFPDPQGPDADVLLVRTGAGAPPAPAAAHENAAR
                     ALALTQRWLADERFAHTRLAFVTTRAVATAPGENVDGLSTAPLWGLLRTVQSEHPDRIT
                     LLDVDGTPEAEELLPAALATGEPQLALRGTQLHVPRLTRDRTPAPVPTPGPDPQGTVLI
                     TGGTGGLGALLARHLVTGHGIRHLLLTSRRGPATPGADRLTAELTELGARVTTLAADAA
                     DPDAVAALLTSVDPAHPLTAIVHTAGVLDDATVESLTPQQLEKVLRPKVDAAWHLHEQT
                     RDLDLAAFVLFSSVSGIIGTAGQANYAAANTYLDALAAHRRAQGLAATSLAWGLWDSSH
                     GMGAQLGQADLARWSRAGIDPLDPDTGLALFDTALTGGDTLVVPALLDLARLRTTAAGD
                     PPALLRGLIRPRATTRAARGTPAAGTHDGTEWVRHLATLPEEESRSAAADLVRTIVADV
                     LGHGSPQSIDPERAFKDIGFDSLAAVELRNRLNTATGLRMPATAVFDHPSPAALAAHLH
                     QQAAGRKPATSTAPARRSSAPADEPIAIIGMACRFPGGVTSPQDLWRLVAEGTDAVSEF
                     PDNRGWDLESLYHPDPEKTGTSYTRHGGFLHDADRFDPAFFGMSPREAIATDPQQRILL
                     ETAWETFESAGIDPALLRGTSTGVFTGAMYDDYASRLAKSPEEFEGFLLAGNLSSVLSG
                     RLAYTYGLEGPALTIDTACSSSLVALHLAAGALRQGECDLALAGGVTVMSGPSTFVEFS
                     RQRGLSEDGRCRSFSADASGTGWAEGAGLLLVEKLSDAHRNGHRVLAVMRGSAVNQDGA
                     SNGLTAPNGPAQERVIRQALAAAGLTPADIDAVEAHGTGTSLGDPIEAQALLATYGQDR
                     PQDRPLHLGSLKSNIGHAQAAAGVGGVIKMIQAMRHGILPRTLHAENPSPHIDWDAGAV
                     RLLTEATPWPATGRPARAAVSSFGISGTNAHVVLELAADNPAPPTPTRTPADSTVIPWI
                     LTAKDENALRRQADRLHHHLTHHPELEAADVGLTLATTRATLEHRAAVLGTDRTTLLDA
                     LARLTAGEPTPSVIRAATTHRGKTAFLLTGQGSQRLGMGRELYETSPVFRSALDDVCRH
                     LDTELFRPVKDVLFAPEGSADSALIDQTAFTQAALFATEVALFRLAEHHGITPDYLLGH
                     SIGEVTAAHLAGVLDLADACTLVAERGRLMQAAREGGAMAALQASEEEVRSVLADYENV
                     AIAGINGPRSTVISGDQDLVEEISALWRMQGRKTKRLPVSHAFHSPHMDEVLDEFRAVA
                     ECLTYHPPRIPVLSNVTGVLATTEQLTSPDYWASHIREPVRFHDGVRHLEELGVTDYLE
                     LGPDGVLTAMAQECLTHEAALLTPLLRSGRPESDTVAAALTAAVLRGTRPHWPSYFPDA
                     RRVDLPTYSFEHTRYWLEGAATPADAEGFGLHGVRHPLLSAAVRVADRDAYLLTGRVSR
                     RTHPWLEGHTVAGTVLLPATALLDLAFRAAEHTDCDTVDELTLAAPLILPEQGAVQLQL
                     VVGEPDETAGRPLAVYARPDQDDTQHPWTLHAQGRLSTTTATPEGLPTWPPADATEVDL
                     DGVYDRLATAGYGYDNAFQGLDRLWKTQDELFAEVTLGEEHRTDAPHFGLHPALLDAAL
                     HPLLPGVTEPEGPSWLPFSWSGVSLHATGATDLRVRLSLNRSGDESLHAALTATDGAGT
                     PVATARSLLLRPLSQETLRAAGTAARDGLFGLGWKPLPTTGTAPARTGWALIPDGTGPR
                     NARALDNALEAGAAPPAVLLLQTSGPAPDVTGDHDTLPQRARTAVRQVLDTVQDWLADD
                     RLAGTRLVVTTRGAVAAGPEDVTDLAHAGVWGLLRSAQTENPGRIVLVDLDPAPTDTDR
                     TAAEDRLLDLAVSSGETQIAVRGDTLTVPRLTRTAPPAQGPAPRWDRGTVLVTGATGTL
                     GTVLARHLVTEHGARRLLLLSRRGPDAPGAAELRTELEALGAHAMTVACDVTDRDSLAG
                     VLATLSDEHPLTAVVHTAGVLDDGVAARLTPDQLDNVLRPKIDAAWHLHELTRDLDLTA
                     FVLYSSVAGLIGTAGQANYAAGNTFLDALAAHRRAHGLPALSLAWGLWAQASTISGSLD
                     DTDLRRLARAGLRPLATQEAMALFDAAPATGEAVLAVTRLDTAVLHGAGDELPPVLRAL
                     AGPAKRRATTAASTGTPQEAPLAQRLASLGPAERERTLTDLVRTQVAGVLGHGDPGRIE
                     ADRAFQELGFDSLTAVELRNQLGRATGLRLPTTLVFDHPSPQALATHLLAELAVEDASP
                     AEPVLAPLAGLETAIAAAPDQETRNLIAARLKELLKAAEAAGSPGGPQDTDDEQNLETA
                     SDEELFALLDELE"
     CDS_motif       1439..1480
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0001"
                     /evalue="2.60E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="58"
                     /protein_start="44"
                     /score="10.4"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPI"
     CDS_motif       1484..1519
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0002"
                     /evalue="2.50E-01"
                     /label="PKSI-KS_m6"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="71"
                     /protein_start="59"
                     /score="5.1"
                     /tool="antismash"
                     /translation="KSNIGHAQAAAG"
     aSDomain        2093..3004
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS21760_PKS_AT.1"
                     /evalue="1.50E-105"
                     /label="ASD51_RS21760_PKS_AT.1"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="566"
                     /protein_start="262"
                     /score="344.8"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQYPGMGRELYESRSEFATALDEVCAALDPHLDLGRPLR
                     DVMFTDTGTGTDTGTDADAGGSGAALLHETRATQPALFALEVALHRTLQAHGLVPDAVA
                     GHSIGELAAAHVAGVLSLDDAATLVAARGRLMQAAVPGGAMLAIQAAESEVAETLTPYA
                     GRLTLAAVNGPDAVVISGDADAADTLAALWRERGRRTRRLTVSHAFHSPHMDTILDEFR
                     TVAEGLTYHAPLLQVVSTLTGRPATGDDLVTPDYWVRQIREAVRFLDATRTLEDEGVTV
                     FVEVGPDAVLTAMADGAFLAGTS"
     aSModule        2093..5695
                     /complete
                     /domains="nrpspksdomains_ASD51_RS21760_PKS_AT.1"
                     /domains="nrpspksdomains_ASD51_RS21760_PKS_DH.1"
                     /domains="nrpspksdomains_ASD51_RS21760_PKS_KR.1"
                     /domains="nrpspksdomains_ASD51_RS21760_PKS_PP.1"
                     /locus_tags="ASD51_RS21760"
                     /monomer_pairings="mal -> ccmal"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     CDS_motif       2096..2143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0003"
                     /evalue="7.10E-07"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="279"
                     /protein_start="263"
                     /score="21.4"
                     /tool="antismash"
                     /translation="FTGQGSQYPGMGRELY"
     CDS_motif       2321..2371
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0004"
                     /evalue="9.70E-03"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="355"
                     /protein_start="338"
                     /score="9.4"
                     /tool="antismash"
                     /translation="ATQPALFALEVALHRTL"
     CDS_motif       2381..2503
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0005"
                     /evalue="1.10E-23"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="399"
                     /protein_start="358"
                     /score="75.5"
                     /tool="antismash"
                     /translation="GLVPDAVAGHSIGELAAAHVAGVLSLDDAATLVAARGRLMQ"
     CDS_motif       2597..2635
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0006"
                     /evalue="5.40E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="443"
                     /protein_start="430"
                     /score="13.2"
                     /tool="antismash"
                     /translation="AAVNGPDAVVISG"
     CDS_motif       2699..2725
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0007"
                     /evalue="7.50E-02"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="473"
                     /protein_start="464"
                     /score="6.5"
                     /tool="antismash"
                     /translation="LTVSHAFHS"
     CDS_motif       2858..2893
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0008"
                     /evalue="2.10E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="529"
                     /protein_start="517"
                     /score="14.7"
                     /tool="antismash"
                     /translation="YWVRQIREAVRF"
     aSDomain        3224..3724
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS21760_PKS_DH.1"
                     /evalue="1.40E-57"
                     /label="ASD51_RS21760_PKS_DH.1"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="806"
                     /protein_start="639"
                     /score="186.7"
                     /tool="antismash"
                     /translation="HPLLATTVDLAEGEGLVLTSSLSLTDHPWLADHRIHGTVLVPATA
                     FIELASAAGRTAGTEHLLELTLEAPLALPEQRPVRVQVAVSAPDTTGTRSFTVHSRPET
                     DDEQTTWTRHVSGALADTPATTDPAFDELLEWPPRDAEAVPPDDTYGQLTDLGYEYGTA
                     FQGL"
     CDS_motif       3308..3385
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0009"
                     /evalue="2.50E-11"
                     /label="PKSI-DH_m2"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="693"
                     /protein_start="667"
                     /score="35.9"
                     /tool="antismash"
                     /translation="WLADHRIHGTVLVPATAFIELASAAG"
     aSDomain        4613..5149
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS21760_PKS_KR.1"
                     /evalue="2.00E-60"
                     /label="ASD51_RS21760_PKS_KR.1"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="1281"
                     /protein_start="1102"
                     /score="195.8"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLITGGTGGLGALLARHLVTGHGIRHLLLTSRRGPATPGADRL
                     TAELTELGARVTTLAADAADPDAVAALLTSVDPAHPLTAIVHTAGVLDDATVESLTPQQ
                     LEKVLRPKVDAAWHLHEQTRDLDLAAFVLFSSVSGIIGTAGQANYAAANTYLDALAAHR
                     RAQGLAATSLAWGLWD"
     CDS_motif       4616..4717
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0010"
                     /evalue="6.70E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="1137"
                     /protein_start="1103"
                     /score="28.4"
                     /tool="antismash"
                     /translation="TVLITGGTGGLGALLARHLVTGHGIRHLLLTSRR"
     CDS_motif       4943..4972
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0011"
                     /evalue="1.50E-02"
                     /label="PKSI-KR_m3"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="1222"
                     /protein_start="1212"
                     /score="8.9"
                     /tool="antismash"
                     /translation="PKVDAAWHLH"
     CDS_motif       4997..5104
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0012"
                     /evalue="4.70E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="1266"
                     /protein_start="1230"
                     /score="67.4"
                     /tool="antismash"
                     /translation="AAFVLFSSVSGIIGTAGQANYAAANTYLDALAAHRR"
     aSDomain        5441..5695
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS21760_PKS_PP.1"
                     /evalue="7.40E-33"
                     /label="ASD51_RS21760_PKS_PP.1"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="1463"
                     /protein_start="1378"
                     /score="104.7"
                     /tool="antismash"
                     /translation="LATLPEEESRSAAADLVRTIVADVLGHGSPQSIDPERAFKDIGFD
                     SLAAVELRNRLNTATGLRMPATAVFDHPSPAALAAHLHQQ"
     aSDomain        5765..7036
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS21760_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="4.00E-182"
                     /label="ASD51_RS21760_PKS_KS.1"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="1910"
                     /protein_start="1486"
                     /score="597.8"
                     /tool="antismash"
                     /translation="IAIIGMACRFPGGVTSPQDLWRLVAEGTDAVSEFPDNRGWDLESL
                     YHPDPEKTGTSYTRHGGFLHDADRFDPAFFGMSPREAIATDPQQRILLETAWETFESAG
                     IDPALLRGTSTGVFTGAMYDDYASRLAKSPEEFEGFLLAGNLSSVLSGRLAYTYGLEGP
                     ALTIDTACSSSLVALHLAAGALRQGECDLALAGGVTVMSGPSTFVEFSRQRGLSEDGRC
                     RSFSADASGTGWAEGAGLLLVEKLSDAHRNGHRVLAVMRGSAVNQDGASNGLTAPNGPA
                     QERVIRQALAAAGLTPADIDAVEAHGTGTSLGDPIEAQALLATYGQDRPQDRPLHLGSL
                     KSNIGHAQAAAGVGGVIKMIQAMRHGILPRTLHAENPSPHIDWDAGAVRLLTEATPWPA
                     TGRPARAAVSSFGISGTNAHVVLEL"
     aSModule        5765..10978
                     /complete
                     /domains="nrpspksdomains_ASD51_RS21760_PKS_KS.1"
                     /domains="nrpspksdomains_ASD51_RS21760_PKS_AT.2"
                     /domains="nrpspksdomains_ASD51_RS21760_PKS_DH.2"
                     /domains="nrpspksdomains_ASD51_RS21760_PKS_KR.2"
                     /domains="nrpspksdomains_ASD51_RS21760_PKS_PP.2"
                     /locus_tags="ASD51_RS21760"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       6248..6295
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0013"
                     /evalue="2.20E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="1663"
                     /protein_start="1647"
                     /score="19.6"
                     /tool="antismash"
                     /translation="GPALTIDTACSSSLVA"
     CDS_motif       6671..6715
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0014"
                     /evalue="9.10E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="1803"
                     /protein_start="1788"
                     /score="11.7"
                     /tool="antismash"
                     /translation="VEAHGTGTSLGDPIE"
     CDS_motif       6776..6820
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0015"
                     /evalue="8.10E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="1838"
                     /protein_start="1823"
                     /score="9.2"
                     /tool="antismash"
                     /translation="GSLKSNIGHAQAAAG"
     aSDomain        7364..8245
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS21760_PKS_AT.2"
                     /evalue="1.20E-109"
                     /label="ASD51_RS21760_PKS_AT.2"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="2313"
                     /protein_start="2019"
                     /score="358.2"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LTGQGSQRLGMGRELYETSPVFRSALDDVCRHLDTELFRPVKDVL
                     FAPEGSADSALIDQTAFTQAALFATEVALFRLAEHHGITPDYLLGHSIGEVTAAHLAGV
                     LDLADACTLVAERGRLMQAAREGGAMAALQASEEEVRSVLADYENVAIAGINGPRSTVI
                     SGDQDLVEEISALWRMQGRKTKRLPVSHAFHSPHMDEVLDEFRAVAECLTYHPPRIPVL
                     SNVTGVLATTEQLTSPDYWASHIREPVRFHDGVRHLEELGVTDYLELGPDGVLTAMAQE
                     CLTHEAALLTPLL"
     CDS_motif       7367..7411
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0016"
                     /evalue="1.10E-04"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="2035"
                     /protein_start="2020"
                     /score="15.0"
                     /tool="antismash"
                     /translation="TGQGSQRLGMGRELY"
     CDS_motif       7547..7594
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0017"
                     /evalue="1.10E+00"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="2096"
                     /protein_start="2080"
                     /score="3.2"
                     /tool="antismash"
                     /translation="FTQAALFATEVALFRL"
     CDS_motif       7607..7729
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0018"
                     /evalue="1.70E-22"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="2141"
                     /protein_start="2100"
                     /score="71.7"
                     /tool="antismash"
                     /translation="GITPDYLLGHSIGEVTAAHLAGVLDLADACTLVAERGRLMQ"
     CDS_motif       7820..7858
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0019"
                     /evalue="7.20E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="2184"
                     /protein_start="2171"
                     /score="9.8"
                     /tool="antismash"
                     /translation="AGINGPRSTVISG"
     CDS_motif       7922..7948
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0020"
                     /evalue="4.10E-02"
                     /label="PKSI-AT-M_m6"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="2214"
                     /protein_start="2205"
                     /score="7.2"
                     /tool="antismash"
                     /translation="LPVSHAFHS"
     CDS_motif       8081..8116
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0021"
                     /evalue="2.80E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="2270"
                     /protein_start="2258"
                     /score="17.4"
                     /tool="antismash"
                     /translation="YWASHIREPVRF"
     aSDomain        8450..8938
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS21760_PKS_DH.2"
                     /evalue="1.70E-56"
                     /label="ASD51_RS21760_PKS_DH.2"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="2544"
                     /protein_start="2381"
                     /score="183.1"
                     /tool="antismash"
                     /translation="HPLLSAAVRVADRDAYLLTGRVSRRTHPWLEGHTVAGTVLLPATA
                     LLDLAFRAAEHTDCDTVDELTLAAPLILPEQGAVQLQLVVGEPDETAGRPLAVYARPDQ
                     DDTQHPWTLHAQGRLSTTTATPEGLPTWPPADATEVDLDGVYDRLATAGYGYDNAFQGL
                     "
     CDS_motif       8534..8611
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0022"
                     /evalue="2.20E-06"
                     /label="PKSI-DH_m2"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="2435"
                     /protein_start="2409"
                     /score="20.2"
                     /tool="antismash"
                     /translation="WLEGHTVAGTVLLPATALLDLAFRAA"
     aSDomain        9902..10438
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS21760_PKS_KR.2"
                     /evalue="3.00E-61"
                     /label="ASD51_RS21760_PKS_KR.2"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="3044"
                     /protein_start="2865"
                     /score="198.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLVTGATGTLGTVLARHLVTEHGARRLLLLSRRGPDAPGAAEL
                     RTELEALGAHAMTVACDVTDRDSLAGVLATLSDEHPLTAVVHTAGVLDDGVAARLTPDQ
                     LDNVLRPKIDAAWHLHELTRDLDLTAFVLYSSVAGLIGTAGQANYAAGNTFLDALAAHR
                     RAHGLPALSLAWGLWA"
     CDS_motif       9905..10006
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0023"
                     /evalue="4.60E-09"
                     /label="PKSI-KR_m1"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="2900"
                     /protein_start="2866"
                     /score="28.9"
                     /tool="antismash"
                     /translation="TVLVTGATGTLGTVLARHLVTEHGARRLLLLSRR"
     CDS_motif       10232..10261
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0024"
                     /evalue="6.10E-02"
                     /label="PKSI-KR_m3"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="2985"
                     /protein_start="2975"
                     /score="7.2"
                     /tool="antismash"
                     /translation="PKIDAAWHLH"
     CDS_motif       10289..10393
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0025"
                     /evalue="1.90E-20"
                     /label="PKSI-KR_m4"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="3029"
                     /protein_start="2994"
                     /score="65.5"
                     /tool="antismash"
                     /translation="AFVLYSSVAGLIGTAGQANYAAGNTFLDALAAHRR"
     aSDomain        10721..10978
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS21760_PKS_PP.2"
                     /evalue="3.40E-34"
                     /label="ASD51_RS21760_PKS_PP.2"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="3224"
                     /protein_start="3138"
                     /score="109.1"
                     /tool="antismash"
                     /translation="LASLGPAERERTLTDLVRTQVAGVLGHGDPGRIEADRAFQELGFD
                     SLTAVELRNQLGRATGLRLPTTLVFDHPSPQALATHLLAEL"
     CDS_motif       10775..10831
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS21760_0026"
                     /evalue="2.90E+01"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="3175"
                     /protein_start="3156"
                     /score="-2.0"
                     /tool="antismash"
                     /translation="TQVAGVLGHGDPGRIEADR"
     aSDomain        11006..11209
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS21760_PKS_Docking_Cterm.
                     1"
                     /evalue="1.50E-10"
                     /label="ASD51_RS21760_PKS_Docking_Cterm.1"
                     /locus_tag="ASD51_RS21760"
                     /protein_end="3301"
                     /protein_start="3233"
                     /score="33.8"
                     /tool="antismash"
                     /translation="PVLAPLAGLETAIAAAPDQETRNLIAARLKELLKAAEAAGSPGGP
                     QDTDDEQNLETASDEELFALLDE"
     gene            11291..>13071
                     /locus_tag="ASD51_RS38195"
                     /old_locus_tag="ASD51_34145"
     CDS             11291..>13071
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (3-30). E-value:
                     3.9e-12. Score: 37.5. Matches aSDomain:
                     nrpspksdomains_ASD51_RS38195_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (35-460). E-value:
                     1.4e-178. Score: 586.1. Matches aSDomain:
                     nrpspksdomains_ASD51_RS38195_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327677.1"
                     /locus_tag="ASD51_RS38195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_34145"
                     /product="type I polyketide synthase"
                     /protein_id="WP_242424560.1"
                     /sec_met_domain="mod_KS (E-value: 1e-230, bitscore: 754.2,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.2e-90, bitscore:
                     291.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADEVQLREYLKRAIADARDARKRLREVEDKEQEPIAIVSMACRY
                     PGGVTSPEDLWQLVADGVDAVSYFPTDRGWDLEGLYDPDPEKTGTSYSREGGFLYDADL
                     FDPELFGMSPREALAADPQQRLLLETAWEAFERAGIDPVSLKGTRTGVFAGIMYNDYGS
                     RPHLPPEDFEGYLFSGSAGSIASGRVAYTYGLEGPAVTIDTACSSSLVALHLAASALRR
                     GECDLALAGGATVMSTPVAFVEFSRLRGLAADGRSKSFSAAADGTGWAEGVGLLLVEKL
                     SDARRNGHRVLAVMRGSAVNQDGASNGLTAPNGPSQERVIRQALAAAGLTPADVDVVEA
                     HGTGTRLGDPIEAQALLATYGQERPHGRPLHLGSLKSNIAHAQAAAGVGGIIKMIQAME
                     HGVLPRTLHSDQPTTHVEWDAGAVSLLNEARPWPDTGAPRRAAVSSFGFGGTNAHVIIE
                     EPPPAEGTTDGPPRTVTLPVMPWIVSGGTATALRDQARRLNARLTADLDVSPLDVGFSL
                     AAGRAVLEHRAVVTGRDRGELLAGVRALAEGGTAPGVVRGERAGGRLGFLFTGQGAQRV
                     GMGVGLCGVFPVFAGVF"
     aSDomain        11300..11380
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS38195_PKS_Docking_Nterm.
                     1"
                     /evalue="3.90E-12"
                     /label="ASD51_RS38195_PKS_Docking_Nterm.1"
                     /locus_tag="ASD51_RS38195"
                     /protein_end="30"
                     /protein_start="3"
                     /score="37.5"
                     /tool="antismash"
                     /translation="EVQLREYLKRAIADARDARKRLREVED"
     aSDomain        11396..12670
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS38195_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.40E-178"
                     /label="ASD51_RS38195_PKS_KS.1"
                     /locus_tag="ASD51_RS38195"
                     /protein_end="460"
                     /protein_start="35"
                     /score="586.1"
                     /tool="antismash"
                     /translation="IAIVSMACRYPGGVTSPEDLWQLVADGVDAVSYFPTDRGWDLEGL
                     YDPDPEKTGTSYSREGGFLYDADLFDPELFGMSPREALAADPQQRLLLETAWEAFERAG
                     IDPVSLKGTRTGVFAGIMYNDYGSRPHLPPEDFEGYLFSGSAGSIASGRVAYTYGLEGP
                     AVTIDTACSSSLVALHLAASALRRGECDLALAGGATVMSTPVAFVEFSRLRGLAADGRS
                     KSFSAAADGTGWAEGVGLLLVEKLSDARRNGHRVLAVMRGSAVNQDGASNGLTAPNGPS
                     QERVIRQALAAAGLTPADVDVVEAHGTGTRLGDPIEAQALLATYGQERPHGRPLHLGSL
                     KSNIAHAQAAAGVGGIIKMIQAMEHGVLPRTLHSDQPTTHVEWDAGAVSLLNEARPWPD
                     TGAPRRAAVSSFGFGGTNAHVIIEEP"
     CDS_motif       11651..11677
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS38195_0001"
                     /evalue="7.40E-03"
                     /label="PKSI-KS_m2"
                     /locus_tag="ASD51_RS38195"
                     /protein_end="129"
                     /protein_start="120"
                     /score="9.2"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     CDS_motif       11879..11926
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS38195_0002"
                     /evalue="2.60E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="ASD51_RS38195"
                     /protein_end="212"
                     /protein_start="196"
                     /score="22.3"
                     /tool="antismash"
                     /translation="GPAVTIDTACSSSLVA"
     CDS_motif       12302..12346
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS38195_0003"
                     /evalue="7.60E-05"
                     /label="PKSI-KS_m5"
                     /locus_tag="ASD51_RS38195"
                     /protein_end="352"
                     /protein_start="337"
                     /score="14.5"
                     /tool="antismash"
                     /translation="VEAHGTGTRLGDPIE"
     CDS_motif       12746..12772
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS38195_0004"
                     /evalue="9.90E+01"
                     /label="PKSI-KS_m5"
                     /locus_tag="ASD51_RS38195"
                     /protein_end="494"
                     /protein_start="485"
                     /score="-3.1"
                     /tool="antismash"
                     /translation="GTATALRDQ"
     CDS_motif       12986..13036
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS38195_0005"
                     /evalue="5.30E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ASD51_RS38195"
                     /protein_end="582"
                     /protein_start="565"
                     /score="15.7"
                     /tool="antismash"
                     /translation="FLFTGQGAQRVGMGVGL"
     assembly_gap    13072
                     /estimated_length=1
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     aSDomain        13121..13561
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS38200_PKS_AT.1"
                     /evalue="1.40E-49"
                     /label="ASD51_RS38200_PKS_AT.1"
                     /locus_tag="ASD51_RS38200"
                     /protein_end="147"
                     /protein_start="0"
                     /score="161.0"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="MGVGLCGVFPVFAGVFDEVCGLFDEVLGGSLRGVIVSGVGLDETG
                     WAQPALFAVEVALFRLVESWGVCPDFVVGHSVGEVVAAHVAGVLSLEDAVGLVVARAGL
                     MQALPVGGAMVAVRAGEEEVLAVLGGRXGVAVAAVNGAGSVVV"
     gene            13121..13606
                     /locus_tag="ASD51_RS38200"
     CDS             13121..13606
                     /NRPS_PKS="Domain: PKS_AT (0-147). E-value: 1.4e-49. Score:
                     161.0. Matches aSDomain:
                     nrpspksdomains_ASD51_RS38200_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="ASD51_RS38200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="acyltransferase domain-containing protein"
                     /protein_id="WP_282434514.1"
                     /sec_met_domain="PKS_AT (E-value: 1.2e-50, bitscore: 161.0,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVGLCGVFPVFAGVFDEVCGLFDEVLGGSLRGVIVSGVGLDETG
                     WAQPALFAVEVALFRLVESWGVCPDFVVGHSVGEVVAAHVAGVLSLEDAVGLVVARAGL
                     MQALPVGGAMVAVRAGEEEVLAVLGGRXGVAVAAVNGAGSVVVRSLRGGXSGRGGCG"
     CDS_motif       13247..13303
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS38200_0001"
                     /evalue="4.50E-05"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="ASD51_RS38200"
                     /protein_end="61"
                     /protein_start="42"
                     /score="16.5"
                     /tool="antismash"
                     /translation="ETGWAQPALFAVEVALFRL"
     CDS_motif       13316..13438
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS38200_0002"
                     /evalue="3.60E-22"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ASD51_RS38200"
                     /protein_end="106"
                     /protein_start="65"
                     /score="70.6"
                     /tool="antismash"
                     /translation="GVCPDFVVGHSVGEVVAAHVAGVLSLEDAVGLVVARAGLMQ"
     gene            13603..>18680
                     /locus_tag="ASD51_RS38205"
                     /pseudo=""
     CDS             13603..>18680
                     /NRPS_PKS="Domain: PKS_DH (200-339). E-value: 1.7e-40.
                     Score: 131.1. Matches aSDomain:
                     nrpspksdomains_ASD51_RS38205_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (646-825). E-value: 4.8e-61.
                     Score: 197.8. Matches aSDomain:
                     nrpspksdomains_ASD51_RS38205_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (920-1006). E-value: 2.2e-31.
                     Score: 100.0. Matches aSDomain:
                     nrpspksdomains_ASD51_RS38205_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (1016-1091). E-value:
                     1.3e-19. Score: 62.8. Matches aSDomain:
                     nrpspksdomains_ASD51_RS38205_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049322.1"
                     /locus_tag="ASD51_RS38205"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /pseudo=""
                     /sec_met_domain="PKS_AT (E-value: 3.3e-31, bitscore: 97.2,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 2.8e-63, bitscore:
                     201.5, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.4e-16, bitscore:
                     49.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSHAFHSPLMDPMLEEFGAALAGVSFGVPRVGVVSTLTGXVAVGE
                     ELRSAGYWVDQVRGTVRFADAVDTMAAQGVTSFLEIGPDAVLSVLAQGAVPALRRDRDE
                     VVSLLSAVGSLFTRGVPVDWRALYAGTGARRVPLPTYAFQRQRYWLEPGPMDWRALYAG
                     TGARRVPLPTYAFQRQRYWLEPGPVPGAHSHDAPTTGHPVLGSPITVAGFNQILFTSRL
                     SLQSHPWLADHVVLGSPVLPASALVELAIHAGDLIGHPALDELNLQVPLVLPHEGNIQL
                     QVRAGTPDDTGRHCLCLYSRPDDFDAPWTMHAEGWYLTEEPETAASLAWDDKTTGRTTE
                     IQLPEGLRTDAGRYGLHPVLLQAALPTRPEDPASGTVPVPADWYGVRLHATGATAVKAR
                     VAEIDDDSYSLQLADAAGNLVVSVESVVFRDIPNEQFTAAVGGDSTGRESLFHLDWTPT
                     ALPETAPPLAWAVLDPDTTGENRYPHPRAVADALASGTHLDAVLLPWPPEHPGTDRIAA
                     THTATRTMLKLVREWLADERLEETRLVVVTSGAVATRDGEDVTDLAGAAVRGLLRSAQS
                     EAPDRIVLIDTDTDTDTTAHADITAPQALPALLAAGEPQAALREGRTLLPRLRRVPATG
                     THTGRAPVWKHGTVLITGGTGTLGAEFARHLVAEHGATRLLLLSRTGEQADGAAGLLDD
                     LRGIGAHVTVATCDASDRDALARVLADIPQEHPLTAVVHTAGVLDNGLIPALTDDGLTD
                     VLRPKADAAWHLHELTRDLELEAFVTFSSTVGVLGGPGQANYAAANAFLDALAAHRHAQ
                     DLPATSIAWSLWQLGGINAHLTESDLNRFARDGFRPIARVEGLALFDRATADSRAALVA
                     TPIGVSAVRAQTRIPALLSELAALPGRRVAHSGPAGPSADDPAAGLAARLGELSEAEQE
                     HLLLTLVRTDVAAVLGRTDAQSIAPGRAFQDLGFDSLTAVDLRNRIGTATGVKLPATLV
                     FDHPTPAALVGYLRDRLTPQEPDAHRTLLDELDRMERTLAAAPQDDQGRSAVSARLRAL
                     LSRVEETGATAPAPGTGLPDPSDAIESASVDELLSFIDNELGNPAT"
     CDS_motif       13756..13791
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS38205_0001"
                     /evalue="7.70E-04"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ASD51_RS38205"
                     /protein_end="63"
                     /protein_start="51"
                     /score="13.0"
                     /tool="antismash"
                     /translation="YWVDQVRGTVRF"
     aSDomain        14203..14619
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS38205_PKS_DH.1"
                     /evalue="1.70E-40"
                     /label="ASD51_RS38205_PKS_DH.1"
                     /locus_tag="ASD51_RS38205"
                     /protein_end="339"
                     /protein_start="200"
                     /score="131.1"
                     /tool="antismash"
                     /translation="HPVLGSPITVAGFNQILFTSRLSLQSHPWLADHVVLGSPVLPASA
                     LVELAIHAGDLIGHPALDELNLQVPLVLPHEGNIQLQVRAGTPDDTGRHCLCLYSRPDD
                     FDAPWTMHAEGWYLTEEPETAASLAWDDKTTGRTT"
     aSModule        14203..16620
                     /domains="nrpspksdomains_ASD51_RS38205_PKS_DH.1"
                     /domains="nrpspksdomains_ASD51_RS38205_PKS_KR.1"
                     /domains="nrpspksdomains_ASD51_RS38205_PKS_PP.1"
                     /incomplete
                     /locus_tags="ASD51_RS38205"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       14287..14361
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS38205_0002"
                     /evalue="1.30E-08"
                     /label="PKSI-DH_m2"
                     /locus_tag="ASD51_RS38205"
                     /protein_end="253"
                     /protein_start="228"
                     /score="27.3"
                     /tool="antismash"
                     /translation="WLADHVVLGSPVLPASALVELAIHA"
     aSDomain        15541..16077
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS38205_PKS_KR.1"
                     /evalue="4.80E-61"
                     /label="ASD51_RS38205_PKS_KR.1"
                     /locus_tag="ASD51_RS38205"
                     /protein_end="825"
                     /protein_start="646"
                     /score="197.8"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTVLITGGTGTLGAEFARHLVAEHGATRLLLLSRTGEQADGAAGL
                     LDDLRGIGAHVTVATCDASDRDALARVLADIPQEHPLTAVVHTAGVLDNGLIPALTDDG
                     LTDVLRPKADAAWHLHELTRDLELEAFVTFSSTVGVLGGPGQANYAAANAFLDALAAHR
                     HAQDLPATSIAWSLWQ"
     CDS_motif       15544..15645
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS38205_0003"
                     /evalue="3.60E-11"
                     /label="PKSI-KR_m1"
                     /locus_tag="ASD51_RS38205"
                     /protein_end="681"
                     /protein_start="647"
                     /score="35.7"
                     /tool="antismash"
                     /translation="TVLITGGTGTLGAEFARHLVAEHGATRLLLLSRT"
     CDS_motif       15922..16032
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS38205_0004"
                     /evalue="2.50E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="ASD51_RS38205"
                     /protein_end="810"
                     /protein_start="773"
                     /score="68.3"
                     /tool="antismash"
                     /translation="LEAFVTFSSTVGVLGGPGQANYAAANAFLDALAAHRH"
     aSDomain        16363..16620
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS38205_PKS_PP.1"
                     /evalue="2.20E-31"
                     /label="ASD51_RS38205_PKS_PP.1"
                     /locus_tag="ASD51_RS38205"
                     /protein_end="1006"
                     /protein_start="920"
                     /score="100.0"
                     /tool="antismash"
                     /translation="LGELSEAEQEHLLLTLVRTDVAAVLGRTDAQSIAPGRAFQDLGFD
                     SLTAVDLRNRIGTATGVKLPATLVFDHPTPAALVGYLRDRL"
     aSDomain        16651..16875
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS38205_PKS_Docking_Cterm.
                     1"
                     /evalue="1.30E-19"
                     /label="ASD51_RS38205_PKS_Docking_Cterm.1"
                     /locus_tag="ASD51_RS38205"
                     /protein_end="1091"
                     /protein_start="1016"
                     /score="62.8"
                     /tool="antismash"
                     /translation="LLDELDRMERTLAAAPQDDQGRSAVSARLRALLSRVEETGATAPA
                     PGTGLPDPSDAIESASVDELLSFIDNELGN"
ORIGIN
        1 gacgaggtgg tgtcgctgct gtcggcggtg gggtccctgt tcacgcgggg tgtgccggtg
       61 gactggcggg ccctgtatgc ggggaccggt gcccgtcggg taccgctgcc cacctacgcc
      121 ttccaacgcc aacgctactg gctcgaaccc ggccccaccg acaggacaac ggcccccgcc
      181 ctcccggcga gcacacccac cgagcccccc gccccccacg gcgaactcgg ccgccggctc
      241 gccaccatgt ccccggcaga ccgcacccgc tccgtcaccg gcctgaccgc cgcccacatc
      301 gccgccgtcc tcggacacga caaggacaac cgccccgacg cccggcactc cttcaaggac
      361 ctcggcttcg actccctgat gtccgtcgaa ctcagagacc ggctcgcgac cgccacaggc
      421 ctgcgcctgc ccggcggcct cctcttcgac cacccgaccc ccgccgcact caccgcgtac
      481 atcgaggccg aactgaccgg ctccgccacc gccgacgaac agcaccccgc caccccgctc
      541 cacgacgacg aacccatcgc catcatcgcc atggcctgcc gctaccccgg cggcatctcc
      601 tcgcccgagg acctgtggcg gctcgtggcc gacggcaaag acgccatctc cggcttcccc
      661 gccgaccgcg gctgggaacc cgacctgtac gaccaggacc ccgagcgctc cggcaagagc
      721 tccgtgcacg aaggcggctt cctgcacgac gccgccctct tcgacgccgc gttcttcggg
      781 atctcgcccc gcgaggccct cgccatggac ccccagcagc gcctcctcct gggagcgcgc
      841 cggcatcgac ccggacaccc tgcgcggcag ccgcaccggc gtcttcgtcg gagccaccgc
      901 cctcgactac ggcccccgcc tgcacgaagc ccccaccagc gtcgaaggcc acctgctcac
      961 cggctccacc agcagcgtca tgtccggacg catcgcctac caactgggac tcgtcggccc
     1021 cgccctcacc atcgacaccg cctgctcctc ctccctcgtc gccctccaca ccgccgtgag
     1081 gtcgctgcgc cagggcgaga cgaccctcgc gatcgcgggc ggcgcgacga tcatgtccgc
     1141 ccccggcatg ttcacggagt tctcacggca gcgcggcctc gccgccgacg gccgcagcaa
     1201 atccttctcc gccgacgccg acggcacctc gtgggccgag ggcgtcggcc tcctcctcgt
     1261 ggagaaactc tccgacgccc gccgcaacgg ccaccaggtc ctcgccgtga tccggggctc
     1321 cgccgtcaac caggacggtg cctccaacgg cctgaccgcc cccaacggcc cctcccagga
     1381 acgtgtcatc cgccaggccc tcgccgacgc ccgcctgacc accgccgacg tggacgccgt
     1441 cgaggcacac ggcaccggca cccgcctcgg cgaccccatc gacaagtcga acatcgggca
     1501 cgcccaggcc gccgccgggg tcggcggtgt catcaagatg gtccaggcga tccgccacgg
     1561 cgtcctcccg cgcaccctgc acgtcaccgc acccaccccg cacgtcgact ggaccaccgg
     1621 cggactggaa ctgctcaccg aggcccgcgc atggcccgcc accgaccgtg cccgccgggc
     1681 cgccgtctcc gccttcggca tcagcggcac caacgcccac gtcatcgtcg agcagccgga
     1741 gaacgacacc cccgaccgcc ccgacgacac ccccgcccac ccccgggacg acaccaccac
     1801 cggctcccga acgcccgccc tgtgggccct ctccgccccc gaccgcgcgg ccctgtcagc
     1861 ccaggccgaa gcactccgca cccacctgga cgaccgcccg gagctcggcg cccaggacat
     1921 cgccgacatc gggttctccc tcgccacctc ccgcgccacc tggcccgagc gggccgtcgt
     1981 caccggcacc gcgaccgcgg aactcctcga cggcctcgac gcactgcgcc ggaccaccga
     2041 cgccccgaac ctggtcaccg gatccgccgc ccgcgcgggc cgcaccgcgt tcctgttcac
     2101 cggccagggc tcccagtacc ccggaatggg ccgagaactg tacgagtcgc gctccgagtt
     2161 cgccaccgcc ctcgacgagg tgtgcgccgc actggacccg cacctcgacc tcggccgccc
     2221 cctgcgcgac gtgatgttca ccgacaccgg caccggcacc gacaccggca ccgatgccga
     2281 tgccggtggg tccggcgccg ccctgctcca cgagacccgc gccacccagc cggcactgtt
     2341 cgccctcgag gtcgccctcc accgcaccct ccaggcccac gggctcgtcc ccgatgccgt
     2401 cgccgggcac tccatcggcg agctcgccgc cgcacacgtc gccggggtcc tctccctcga
     2461 cgacgccgcc accctggtcg ccgcccgcgg ccggctcatg caggcggcgg tccccggcgg
     2521 cgcgatgctc gcgatccagg ccgcggagag cgaggtcgcc gaaaccctca ccccctacgc
     2581 cggccggctc accctcgccg ccgtcaacgg cccggacgcc gtcgtcatct ccggcgacgc
     2641 cgacgccgcg gacacactcg ccgcactctg gcgcgaacgc ggccgcagaa cacgccgcct
     2701 gacagtcagc cacgccttcc actcaccgca catggacacc atcctcgacg agttccgaac
     2761 cgtcgccgag ggcctgacct accacgcacc gctcctccag gtcgtctcca ccctcaccgg
     2821 ccggccggcc accggcgacg acctcgtcac ccccgactac tgggtgcgcc agatacgcga
     2881 agccgtacgc ttcctcgacg ccacccgcac gctcgaggac gagggcgtca ccgtcttcgt
     2941 cgaggtcggc cccgacgccg tcctcaccgc gatggcagac ggcgcgttcc tggccggcac
     3001 ctcccaggcc gtcgccctcc agcgggccgg ccgcccccag ggcaccgccc tcaccaccgg
     3061 cctcgcccgc gcccacaccc tcggcgcccc cctcgacctg gcatcgctct tccccggcgc
     3121 ctcgcgcgtc gaactgccca cctacgcgtt ccggcgcagc cactactggc tccggccccg
     3181 gacccgcacc gacgcccgag gcctcggact cgacccggcc ggccaccccc tcctggccac
     3241 caccgtcgac ctcgccgagg gcgagggcct cgtcctcacc agcagcctgt cgctgaccga
     3301 ccacccctgg ctcgccgacc accgcatcca cggcaccgtc ctcgtacccg ccaccgcgtt
     3361 catcgagctc gcctcggcag cgggccggac cgccggcacc gaacacctcc tcgagctcac
     3421 cctcgaagcc ccgctcgccc tacccgaaca gcggcccgtc cgcgtccagg tcgccgtcag
     3481 cgcccccgac accacaggca cccgctcctt caccgtgcac tcccggcccg agaccgacga
     3541 cgagcagacc acctggaccc gccacgtctc cggcgccctc gccgacaccc ccgccaccac
     3601 cgaccccgcc ttcgacgaac tgctcgaatg gccgccccgg gacgcggaag ccgtcccccc
     3661 ggacgacacc tacgggcagc tcaccgacct cggctacgag tacggcaccg ccttccaagg
     3721 gctgcgcgcc ctgtggcgcg gcaggaacgg caccacctac gccgacatcg ccctgcccgc
     3781 cgaccagcac gaggccgccg ccggctacgg catccacccc gcactcctgg acgccgccct
     3841 ccacccggtc gtcctcgaca ccgccgacac caccgaaccg gacaccatcc ggctgccgtt
     3901 cgcctggagc ggggtcacca cccatgccgt cggcgccacc accctgcgcg tccgcatccg
     3961 gcacaccggc cccgacacgg tcgccctgca cctggccgac gccaccggcg ctcccgtcgc
     4021 caccatcgac tcgctgatgc tgcgccccgt cgccaaggac cggctcgccc cggcggccac
     4081 cacggacggc ctcttcaccc tcgcctggcc ctcactcgcc ccgccgggcg gccccgcacc
     4141 gcgcatcgcc gaactccccg ccggcaccga cgccttcccc gacccgcaag gacccgacgc
     4201 cgacgtccta ctcgtccgca ccggcgccgg cgctcccccc gccccggccg cagcccacga
     4261 gaacgcagcc cgcgccctcg ccctgaccca gcggtggctc gccgacgaac gattcgccca
     4321 cacccgcctc gcgttcgtca ccacccgcgc agtcgccacc gcccccggcg aaaacgtcga
     4381 cggcctgtcc accgcccccc tctggggcct gctccgcacc gtccagagcg aacaccccga
     4441 ccgcatcacc ctcctggacg tcgacggcac ccccgaggcc gaggaactgc tgcccgccgc
     4501 cctggccacc ggcgaacccc aactcgccct gcgcggcaca caactgcacg tcccacgcct
     4561 cacccgcgac cggacccccg cacccgtccc cacgcccggc cccgacccgc agggcaccgt
     4621 cctcatcacc ggcggcacag gcggcctcgg cgcactcctc gcccgccacc tcgtgaccgg
     4681 gcacggaata cgccacctcc tgctcaccag ccgacgcgga cccgccaccc ccggagccga
     4741 ccggctcacc gccgaactca ccgaactcgg cgcccgggtg accaccctcg ccgccgacgc
     4801 cgccgacccg gacgccgtcg ccgccctcct gacatccgtc gaccccgcac acccgctcac
     4861 cgcgatcgtg cacaccgccg gtgtcctgga cgacgccacc gtcgaatccc tcaccccaca
     4921 acagctggag aaggtcctgc ggcccaaggt cgacgccgcc tggcacctgc acgagcagac
     4981 ccgcgacctg gacctggccg ccttcgtcct gttctcctcc gtctccggca tcatcggcac
     5041 cgcgggccag gccaactacg ccgccgccaa cacctacctc gacgcactcg cggcccaccg
     5101 ccgggcccag ggcctggccg ccacctcgct ggcctggggc ctgtgggact ccagccacgg
     5161 catgggcgcc cagctcggcc aggccgacct ggcccgctgg agccgggccg gcatcgaccc
     5221 gctcgacccg gacaccggcc tcgccctgtt cgacaccgcc ctcaccggcg gcgacaccct
     5281 ggtcgtaccc gccctcctgg acctcgcccg gctccgtacc accgcggccg gcgacccgcc
     5341 cgccctgctg cgcgggctga tccgcccccg cgccaccaca cgggccgccc ggggaacgcc
     5401 ggccgcggga acgcacgacg gcaccgaatg ggtccgccac ctcgccaccc tccccgagga
     5461 ggagagccgt tccgccgccg cggacctcgt acgcaccatc gtcgccgacg tcctcggcca
     5521 cgggagcccg cagagcatcg acccggaacg cgccttcaag gacatcgggt tcgactccct
     5581 ggccgcggtg gaactacgca accggctcaa caccgccacc ggactgcgga tgcccgccac
     5641 cgccgtcttc gaccacccct cgcccgccgc cctcgccgcc cacctgcacc agcaggccgc
     5701 cggccgcaag cccgccacca gcaccgcacc cgcccgccgg tccagcgcac ccgccgacga
     5761 gcccatcgcc atcatcggca tggcctgccg cttccccggc ggcgtcacct caccccagga
     5821 cctgtggcgg ctcgtcgccg aaggcaccga cgccgtcagc gaattccccg acaaccgggg
     5881 ctgggacctg gaatccctct accacccgga cccggagaag accggcacct cctacacccg
     5941 ccacggcgga ttcctccacg acgccgaccg gttcgacccg gcgttcttcg gaatgtcacc
     6001 gcgcgaagcc atcgccaccg acccccagca gcgcatcctc ctcgaaaccg cctgggagac
     6061 cttcgagagc gccggcatcg accccgcact cctgcgaggc accagcaccg gcgtcttcac
     6121 cggcgccatg tacgacgact acgcctcccg gctcgccaag agcccggagg agttcgaggg
     6181 cttcctgctc gccggcaacc tctccagcgt cctctccggc cgcctcgcct acacatacgg
     6241 cctcgaaggc cccgccctca ccatcgacac cgcctgctcc tcctccctcg tcgccctgca
     6301 cctcgcggcc ggcgccctgc gccaggggga gtgcgacctc gccctcgccg gcggcgtcac
     6361 cgtgatgtcc ggccccagca ccttcgtcga gttctcccgg cagcgcggcc tctccgagga
     6421 cggccgctgc cgctccttct ccgccgacgc ctccggcacc ggctgggcag aaggagcggg
     6481 cctcctcctc gtggagaaac tctccgacgc ccaccgcaac ggccaccggg tcctggccgt
     6541 catgcgcggc tccgccgtca accaggacgg cgcttccaac ggcctgaccg cccccaacgg
     6601 ccccgcccag gaacgcgtca tccgccaggc cctggccgcc gcgggcctca cccccgccga
     6661 catcgacgcg gtcgaggccc acggcaccgg caccagcctc ggcgacccca tcgaggcaca
     6721 ggccctgctc gccacctacg gacaggaccg cccccaggac cgccccctcc acctcggctc
     6781 cctcaagtcg aacatcgggc acgcccaggc cgcggccggc gtcggcggcg tcatcaagat
     6841 gatccaggcc atgcgccacg gcatcctccc caggacactg cacgccgaaa acccctcccc
     6901 ccacatcgac tgggacgcgg gcgcggtgcg actactcacc gaggcgacac cctggcccgc
     6961 caccggccgc cccgcccgag ccgccgtatc gtccttcggg atcagcggca ccaacgccca
     7021 cgtcgtcctg gaactcgccg ccgacaaccc ggcaccgccc acacccaccc gcaccccggc
     7081 cgacagcacc gtcatcccct ggatcctgac cgcgaaggac gagaacgccc tgcgccgcca
     7141 ggcagaccgg ctccaccacc acctcaccca ccaccccgag ctcgaagcgg ccgacgtcgg
     7201 cctcaccctg gccaccaccc gcgccaccct ggaacaccgc gccgccgtcc tcggcaccga
     7261 ccgcacgaca ctcctggacg cactggcccg cctcaccgcc ggcgaaccga caccctccgt
     7321 catacgcgcc gccaccaccc accgcggcaa aacagccttc ctgctcaccg gacaaggcag
     7381 ccagcggctc ggcatgggac gcgaactgta cgagacgtcc cccgtcttcc gcagcgccct
     7441 cgacgacgtg tgcaggcacc tggacaccga actgttccgg cccgtcaaag acgtcctctt
     7501 cgcccccgaa ggctcagcgg actcggccct catcgaccag accgccttca cccaagccgc
     7561 cctcttcgcc accgaggtcg ccctcttccg actggccgaa caccacggca tcaccccgga
     7621 ctacctcctc ggccactcca tcggagaggt caccgccgcc cacctggccg gcgtcctgga
     7681 cctcgccgac gcgtgcaccc tcgtcgccga acgcggccgg ctcatgcagg cggcacgcga
     7741 gggcggcgca atggcagccc tccaggcctc cgaggaagaa gtacggtccg tactcgccga
     7801 ctacgaaaac gtcgccatcg ccggaatcaa cggcccccgc tccaccgtca tctcaggcga
     7861 ccaggacctc gtcgaagaaa tcagcgccct gtggcgcatg cagggccgca agaccaagcg
     7921 gctgcccgtc agccacgcct tccactcacc gcacatggac gaagtgctcg acgaattccg
     7981 cgccgtcgcc gagtgcctca cctaccaccc accccgcatc cccgtcctct ccaacgtcac
     8041 cggagtcctc gccaccaccg aacagctcac ctcacccgac tactgggcct cccacatccg
     8101 cgagccggtc cgcttccacg acggcgtccg ccacctcgaa gaactcggcg tgaccgacta
     8161 cctggaactc ggccccgacg gcgtcctgac cgccatggcc caggaatgcc tcacccacga
     8221 agccgccctc ctcacccccc tcctgcgctc gggcagaccc gagagcgaca ccgtcgcagc
     8281 cgccctcacc gccgccgtcc tgcgcggcac acgcccccac tggccctcgt acttccccga
     8341 cgcccgccgc gtcgacctgc ccacctactc cttcgagcac acccgctact ggctggaggg
     8401 cgcagccacc cccgccgacg ccgaaggatt cggcctccac ggcgtccgcc accccctgct
     8461 cagcgcggcc gtacgggtcg cggaccggga cgcctacctc ctcaccggcc gcgtctcccg
     8521 ccgcacacac ccctggctgg aaggccacac ggtggccggc accgtcctgc tgcccgccac
     8581 cgcactgctc gacctcgcct tccgcgccgc cgaacacacc gactgcgaca cggtcgacga
     8641 actgaccctc gccgcaccgc tgatcctgcc cgaacaaggc gccgtccaac tgcagctcgt
     8701 cgtcggcgaa cccgacgaga ccgcaggccg ccccctcgcc gtctacgccc ggcccgacca
     8761 ggacgacaca caacacccct ggaccctgca cgcccaagga cgcctctcca ccaccaccgc
     8821 cacccccgaa ggactcccca cctggccccc ggccgacgcc acagaagtgg acctcgacgg
     8881 cgtctacgac cggctcgcca ccgccggata cggctacgac aacgccttcc agggcctgga
     8941 ccgcctctgg aagacacagg acgaactctt cgccgaagtc accctcggcg aggaacaccg
     9001 caccgacgcc ccgcacttcg gcctccaccc cgccctcctg gacgccgccc tgcacccact
     9061 gctccccggc gtcaccgaac cagaaggccc ctcctggctg cccttctcct ggtccggagt
     9121 gagcctgcac gccaccggag cgaccgacct gcgggtacgg ctctccctca accggtccgg
     9181 cgacgaatcc ctccacgccg ccctcaccgc caccgacggc gccggcaccc ccgtcgccac
     9241 cgccagatcc ctcctgctgc gccccctgtc ccaggaaaca ctccgcgccg ccggcaccgc
     9301 cgcacgcgac ggcctgttcg gcctcggctg gaagcccctg cccaccaccg gcacggcccc
     9361 ggcccgcacc ggctgggccc tgatccccga cggcaccggc ccacgaaacg cccgggccct
     9421 cgacaacgca ctcgaagcgg gcgccgcacc accggccgta ctcctcctgc agacatccgg
     9481 ccccgccccc gacgtcaccg gcgaccacga caccctgccc cagcgggccc gcaccgccgt
     9541 acgacaggtc ctcgacaccg tgcaggactg gctcgccgac gaccggctcg ccgggacccg
     9601 gctcgtcgtc accacccggg gagccgtcgc cgccggaccc gaggacgtca ccgacctggc
     9661 ccacgccgga gtctggggcc tgctccgctc cgcacagacc gaaaaccccg gccggatcgt
     9721 cctcgtcgac ctcgaccccg cccccaccga cacagaccgc accgccgcgg aggaccggct
     9781 cctggacctc gccgtatcca gcggggaaac ccagatcgcc gtccgcggcg acaccctcac
     9841 cgtcccccgg ctcacccgca ccgccccgcc ggcccaaggc ccggcacccc gatgggaccg
     9901 gggcaccgtc ctcgtcaccg gcgcgaccgg caccctgggc accgtcctcg cccggcacct
     9961 cgtcaccgaa cacggagccc gccggctgct gctgctcagc cgccgcggcc ccgacgcccc
    10021 cggcgccgcc gaactccgca ccgaactgga agcactcggc gcccacgcga tgaccgtcgc
    10081 ctgcgacgtg accgaccgcg actccctggc cggcgtcctc gccaccctct ccgacgagca
    10141 cccgctgacc gccgtcgtcc acaccgccgg cgtcctcgac gacggcgtcg ccgcccggct
    10201 cacccccgac caactcgaca acgtcctgcg ccccaagatc gacgccgcct ggcacctgca
    10261 cgaactcacc cgggacctgg acctcacagc cttcgtcctc tactcctccg tggccggcct
    10321 catcggcacc gcgggccagg ccaactacgc ggccggcaac accttcctgg acgccctagc
    10381 cgcccaccgc cgcgcccacg gcctgcccgc actgtccctc gcctggggcc tgtgggccca
    10441 ggcgagcacc atctccggca gtctcgacga caccgacctg cgccgcctgg cccgcgccgg
    10501 cctgcgtccc ctcgccaccc aggaggcgat ggccctcttc gacgcggccc ccgccaccgg
    10561 cgaggccgtc ctcgccgtca cccgcctcga cacggcggtc ctgcacggcg caggcgacga
    10621 actgcccccc gtcctgcgcg ccctcgccgg gccggccaag cgccgcgcca ccaccgccgc
    10681 gagcaccggg acgcctcagg aggcccccct cgcccaacgc ctcgcctccc tcggccccgc
    10741 cgaacgcgaa cgcaccctca ccgatctcgt acgcacccag gtcgcgggtg tcctgggaca
    10801 cggggacccc ggccgcatcg aggccgaccg ggccttccag gaactcggct tcgactcgct
    10861 caccgccgtc gaactccgca accagctcgg ccgggccacc ggactgcgcc tgccgaccac
    10921 cctcgtcttc gaccacccct ccccgcaggc gctcgccacc cacctcctgg ccgaactggc
    10981 cgtggaggac gcctcaccgg cggaaccggt cctcgccccc ctcgccggtc tggagacggc
    11041 catcgccgcc gcaccggacc aggagacgcg caacctgatc gccgcacggc tcaaggaact
    11101 cctcaaggcg gccgaggccg ccggcagccc cggaggacca caggacaccg acgacgagca
    11161 gaacctcgaa acggcgagcg acgaggaact cttcgcactg ctggacgaac tcgaatgacc
    11221 cgccaggcac gcgccgccca cggcacgcac acggcaatcg gacacaccat caccggggag
    11281 ctgaattcac gtggctgacg aggtacaact ccgcgaatac ctcaagaggg ccatcgccga
    11341 cgcccgggac gcacgcaagc gtctgcgcga ggtcgaggac aaggaacagg agccgatcgc
    11401 catcgtctcc atggcctgcc gctaccccgg aggcgtcacc tcgcccgagg acctgtggca
    11461 actggtggcc gacggagtcg acgcggtctc ctacttcccc accgaccgcg gctgggacct
    11521 ggagggcctc tacgaccccg acccggagaa gaccggcacc tcctactccc gtgagggcgg
    11581 attcctctac gacgccgacc tcttcgaccc cgaactgttc gggatgtccc cacgcgaggc
    11641 cctggcggcc gacccccagc agcgactcct cctggagacc gcctgggagg ccttcgaacg
    11701 ggccggcatc gacccggtct cgctcaaggg cacccggacc ggcgtgttcg ccggcatcat
    11761 gtacaacgac tacggctcac gcccccacct ccccccggag gacttcgagg gctacctgtt
    11821 cagcggcagc gcgggctcca tcgcctcggg ccgcgtcgcc tacacgtacg gcctcgaagg
    11881 cccggccgtc accatcgaca ccgcctgctc ctcctccctc gtcgccctgc acctcgcggc
    11941 cagcgccctg cgccgcggcg agtgcgacct ggccctcgcc ggcggcgcca ccgtgatgtc
    12001 gacaccggtc gccttcgtcg agttctcccg gctgcgcgga ctggcggccg acggccgcag
    12061 caagtccttc tccgcagccg cggacggcac cggctgggcc gagggagtgg gcctcctcct
    12121 cgtggagaag ctgtccgacg cccgccgcaa cggccaccgg gtcctggccg tcatgcgcgg
    12181 ctccgccgtc aaccaggacg gtgcctccaa cggtctgacc gcccccaacg gcccctccca
    12241 ggagcgcgtc atccgccagg ccctggccgc cgcgggcctc acccccgccg acgtggacgt
    12301 cgtcgaggcg cacggcaccg gcacccgcct cggcgacccc atcgaggcac aggcgctgct
    12361 ggccacctac gggcaggaac ggccgcacgg ccgtcccctc cacctcggct ccctcaagtc
    12421 gaacatcgcc cacgcccagg ccgcggccgg cgtcggcggc atcatcaaga tgatccaggc
    12481 catggagcac ggcgtgctgc cccgcaccct gcacagcgat cagcccacca cccacgtcga
    12541 atgggacgcg ggagccgtct ccctgctcaa cgaggccagg ccctggcccg acaccggggc
    12601 cccgcgccgc gcggccgtct cctcgttcgg cttcggcggc acgaacgccc acgtgatcat
    12661 cgaggagccg ccgccggccg aaggaaccac ggacggcccc ccgcggacgg tgacgctccc
    12721 cgtcatgccg tggatcgtct ccggcgggac cgccaccgcc ctgcgggacc aggcgcgacg
    12781 gctgaacgcc cgcctcaccg cggacctcga cgtgtccccg ctggatgtgg gtttctccct
    12841 ggcggcgggg agggcggttc tggagcatcg tgcggtggtg acggggcggg accgtgggga
    12901 gttgctggcg ggggtgcgtg cgctggcgga gggcgggacg gctccgggtg tggtgcgtgg
    12961 tgagcgtgcc ggtggtcggt tgggttttct gtttacgggt cagggtgcgc agcgggtggg
    13021 gatgggggtg ggtttgtgtg gggtgtttcc ggtgtttgcg ggtgtgtttg anggtcggtt
    13081 gggttttctg tttacgggtc agggtgcgca gcgggtgggg atgggggtgg gtttgtgtgg
    13141 ggtgtttccg gtgtttgcgg gtgtgtttga tgaggtgtgt gggttgtttg atgaggtttt
    13201 gggtggttcg ttgcgtgggg tgattgtgtc gggtgtgggt ctggatgaga cggggtgggc
    13261 tcagccggcg ttgttngcgg tggaggttgc tttgtttcgt ttggtggagt cgtggggtgt
    13321 gtgtcctgat tttgtggtgg ggcattcggt gggtgaggtg gtggcggctc atgtggcggg
    13381 ggtgttgtcg ctngaggatg cggtggggtt ggtggtggcg cgtgcggggt tgatgcaggc
    13441 gttgccggtg ggtggggcga tggtcgcggt ccgggcgggg gaggaggagg ttctggctgt
    13501 gctggggggn cggnccgggg ttgctgttgc tgcggtgaat ggtgcggggt cggtggtggt
    13561 gcggagcttg aggggagggg nttcgggtcg aggcggttgc gggtgagtca tgcgtttcat
    13621 tcgccgttga tggatccgat gctggaggag ttcggggcng cgttggcggg ggtttcgttc
    13681 ggggtgccgc gggtgggtgt ggtgtcgacg ctnacgggcn nggtcgcggt gggtgaggag
    13741 ttgcggtcgg cngggtactg ggtggatcag gtgcgtggga cggtgcgttt cgctgacgcg
    13801 gtcgacacga tggccgccca gggagtgacg tcgtttctgg agatcgggcc cgacgcggtg
    13861 ctgtcggtgc tggcgcaggg tgcggttccg gcgttgcgcc gggaccgtga cgaggtggtg
    13921 tcgctgctgt cggcggtggg gtccctgttc acgcggggtg tgccggtgga ctggcgggcc
    13981 ctgtatgcgg ggaccggtgc ccgtcgggta ccgctgccca cctacgcctt ccaacgccaa
    14041 cgctactggc tcgaacccgg ccccatggac tggcgggccc tgtatgcggg gaccggtgcc
    14101 cgtcgggtac cgctgcccac ctacgccttc caacgccaac gctactggct cgaacccggc
    14161 cccgtccccg gggcccacag ccacgacgcc cccaccaccg gccaccccgt cctcggatca
    14221 cccatcaccg tggccggctt caaccagatc ctgttcacca gccgcctctc cctgcagagc
    14281 cacccctggc tcgccgacca cgtcgtgctc ggctcacccg tcctcccggc atcggccctg
    14341 gtcgaactcg ccatccacgc aggcgacctg atcggccacc cggcactcga cgaactcaac
    14401 ctccaggtcc ccctggtact cccgcacgaa ggcaacatcc agctccaggt cagggccgga
    14461 accccggacg acaccggacg gcactgcctg tgcctctact cccgccccga cgacttcgac
    14521 gcaccatgga ccatgcacgc ggagggctgg tacctcaccg aggagcccga gaccgcagcc
    14581 tccctcgcct gggacgacaa aacgaccggc cggaccacgg agatccagct ccccgaaggc
    14641 ctccgcaccg acgccggccg atacggactg caccccgtcc tgctgcaggc ggccctgccc
    14701 acccgccccg aagacccggc atccggcacc gtcccggtcc ccgccgactg gtacggcgta
    14761 cgcctccacg ccaccggagc caccgccgtc aaggcacggg tcgcagagat cgacgacgac
    14821 tcctactcac tccaactcgc cgacgcggcc ggcaacctgg tcgtctcggt ggagtccgtc
    14881 gtcttccgcg acatacccaa cgaacagttc acagccgccg tcggcggcga cagcacagga
    14941 cgcgaatccc tcttccacct cgactggacc cccaccgcac tgccggagac cgccccaccg
    15001 ctcgcctggg ccgtcctgga ccccgacacc accggcgaga accgctaccc gcacccccga
    15061 gccgtggccg acgccctggc ctccggcacc cacctcgacg cggtcctgct gccctggccc
    15121 cccgaacacc ccggcaccga ccggatcgcc gccacccaca cagccacccg caccatgctg
    15181 aagctggtgc gcgagtggct ggccgacgag cgcctggagg agaccaggct cgtggtcgtc
    15241 acctcgggag cggtcgccac ccgcgacgga gaagacgtca ccgacctcgc cggcgccgcc
    15301 gtccggggcc tgctccgctc cgcccagtcg gaagcccccg accgcatcgt cctcatcgac
    15361 accgacaccg acaccgacac cacggcccac gccgacatca ccgcccccca ggcactgccc
    15421 gccctcctcg ccgccggcga accccaggcc gccctgcgcg aaggcaggac actcctgccc
    15481 cgcctacgac gagtccccgc caccggcaca cataccggcc gggcccccgt ctggaagcac
    15541 ggcaccgtcc tcatcaccgg cggcaccggc accctcggcg ccgaattcgc ccgccacctc
    15601 gtcgccgaac acggcgccac ccggctcctg ctgctctccc gcaccgggga acaggccgac
    15661 ggcgcggcag gcctcctgga cgacctgcgg ggcatcggcg cccacgtcac cgtcgccacc
    15721 tgcgacgcaa gcgatcgcga cgcgctcgcc cgggtactcg ccgacatccc gcaggaacac
    15781 ccgctgaccg cggtcgtgca caccgccggc gtactcgaca acgggctgat ccccgcactc
    15841 accgacgacg gactcaccga cgtactgcga cccaaggcgg acgccgcctg gcacctgcac
    15901 gagctgaccc gggacctgga actcgaggcg ttcgtgacgt tctcctccac cgtgggcgtc
    15961 ctgggcggcc ccggccaggc caactacgcg gcagccaacg ccttcctgga cgccctcgcc
    16021 gcacaccggc acgcccagga cctgccggcg acctccatcg cctggagcct gtggcaactg
    16081 ggcggcatca acgcccacct gaccgagagc gacctcaacc gcttcgcccg cgacggcttc
    16141 cggccgatcg cacgcgtcga aggcctcgcc ctgttcgacc gggccaccgc cgacagccgg
    16201 gccgccctcg tcgcgacacc gatcggtgtg tccgcggtac gggcccagac ccggatcccc
    16261 gccctgctga gcgaactcgc ggcactaccg ggccggcgcg tcgcccactc cggacccgcc
    16321 ggcccctccg ccgacgaccc ggcggccggc ctcgccgcac gactgggcga actgagcgag
    16381 gcggaacagg aacacctgct cctcaccctc gtacgcaccg atgtcgccgc ggtcctcggc
    16441 cgtaccgacg cccagtccat cgcaccggga cgagccttcc aggacctggg cttcgactcc
    16501 ctcaccgcgg tcgacctgcg caaccggatc ggcaccgcca ccggggtcaa gctccccgcc
    16561 accctcgtgt tcgaccaccc cacccccgcc gccctcgtcg gatacctgcg ggaccgcctc
    16621 acaccgcagg aaccggacgc ccaccggaca ctgctcgacg aactggaccg gatggaacgg
    16681 acgctggccg ccgcacccca ggacgaccag ggccgctccg ccgtctccgc ccgcctgcgg
    16741 gcactgctgt cccgagtcga ggagaccggc gccacggccc cggcgcccgg gaccggcctg
    16801 cccgacccgt ccgacgccat cgagtcggcc tccgtcgacg aactcctcag cttcatcgac
    16861 aacgaactcg gcaaccccgc cacctagcga ccggtccgcc ccggtggcgg acacggaacc
    16921 ccaagccggt ccggcggccc ctcgccggac cggccggccc cctgccactc agccttccgc
    16981 ccgaggagca tcaacccgat gtccaacccg tcgaacgaag agaagctggt cgagtacctc
    17041 aagcgggtca cggtcgacct gcagaaggcc aaccgcaaga tcgccgcact cgaggcggcc
    17101 gagtccgagc cgatcgccgt cgtcggcatg gcctgccgct tccccggcgg agtgacgtcc
    17161 cccgacggac tgtggcacct ggtcgactcc ggaaccgacg ccatcaccga cttccccacc
    17221 gaccgcggct gggacctgga gggcctctac gaccccgacc cggggacgcc gccctcttcg
    17281 acgccgcgtt cttcgggatc tcgccccgcg aggccctcgc catggacccc cagcagcgcc
    17341 tcctcctgga gacctcctgg gaagcgctcg agcaggccgg catcgacccc gacaccctgc
    17401 gcggcagccg caccggcgtc ttcgccggga tcatcgagca gagctacctc ggcctgcacg
    17461 gacccgagga gttcgagggc tatctgctga ccagcaaact cagcagcgtc gcctccggcc
    17521 gggtcgccta cagcctcggc ctcgaaggcc ccgccctctc cgtcgacacc gcctgctcct
    17581 cctccctcgt cgccctccac ctcgcgatcc agtcgctgcg ctccggcgag tccgacctcg
    17641 ccctggccgg cggcgtcacg gtcaccgcga cccccggcgg attcatcgac ttctcccggc
    17701 agagcggcct ggcgcccgac ggccgcatca agtccttctc cgccgacgcg gacggcacct
    17761 cgtggtcgga aggcgtcggc atgctcgtcg tggaaaagct gtccgacgcc cgccgcaacg
    17821 gccaccgggt cctcgccgtg gtccgcggct ccgccgtcaa ccaggacggt gcctccaacg
    17881 gcctcgcctg accaccgccg acgtggacgc cgtcgaggca cacggcaccg gcacccgcct
    17941 cggcgacccc atcgaggcac aggcgatcct cgccacctac gggcagggcc gccccgaagg
    18001 ccgtcccctc tacctcggct ccctcaagtc gaacatcggg cacaccgtcg ccgccgccgg
    18061 cgtcggcggc gtcatcaaga tgatccaggc catggagcac ggcgtgctgc cccgcaccct
    18121 gcacgtggag agccccacac cgatggcgga ctgggactcc ggcgccgtcg aactgctcac
    18181 cggggcccgc gcatggccgg ccaccgaccg cgcccgccgg gccgccgtct ccgccttcgg
    18241 cgtcagcggc accaacgccc acgtgatcat cgagcagccg cccgcggagg agcctgccga
    18301 gccggcgccg gccgggacgg ccggcctgcc cgtgatcccc tggccgatct cgggcaggac
    18361 accgcaggcc ctgcgggagc aggcccgccg cctcctcgac cacatctcgg ccgacacgag
    18421 cctctccccg ctggatgtgg gtttctctct ggcggcgggg agggcggttc tggagcatcg
    18481 tgcggtggtg acggggcggg accgtgggga gttgctggcg ggggtgcgcg cgctggcgga
    18541 cggcgaacag ggggccggtg tggtgacggg ggcggttcag ggcggtcggt tgggttttct
    18601 gtttacgggt cagggtgcgc agcgggtggg gatgggggtg ggtttgtgtg gggtgtttcc
    18661 ggtgtttgcg ggtgtgtttg
//
