LOCUS       NZ_LMFT01000023        10849 bp    DNA     linear   CON 07-JUN-2024
DEFINITION  Streptomyces sp. Root55 contig_3, whole genome shotgun sequence.
ACCESSION   NZ_LMFT01000023
VERSION     NZ_LMFT01000023.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root55
  ORGANISM  Streptomyces sp. Root55
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 673853)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 673853)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140605
            Assembly Name                     :: Root55
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001427245.1-RS_2024_06_07
            Annotation Date                   :: 06/07/2024 01:50:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,084
            CDSs (total)                      :: 7,008
            Genes (coding)                    :: 6,730
            CDSs (with protein)               :: 6,730
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (5S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 278
            CDSs (without protein)            :: 278
            Pseudo Genes (ambiguous residues) :: 0 of 278
            Pseudo Genes (frameshifted)       :: 105 of 278
            Pseudo Genes (incomplete)         :: 225 of 278
            Pseudo Genes (internal stop)      :: 24 of 278
            Pseudo Genes (multiple problems)  :: 67 of 278
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:11:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 397176
            Orig. end                         :: 408025
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMFT01000023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10849
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /region_number="1"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..10849
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10849
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5849](-)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5849)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     misc_feature    238..252
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
     misc_feature    662..677
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.48"
                     /tool="antismash"
     gene            696..1016
                     /locus_tag="ASD51_RS20505"
                     /old_locus_tag="ASD51_08875"
     CDS             696..1016
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960830.1"
                     /locus_tag="ASD51_RS20505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_08875"
                     /product="SCO5918 family protein"
                     /protein_id="WP_056793268.1"
                     /transl_table=11
                     /translation="MRCVIARFPFDLFKNEVEDSMKGIKPEPVTGDAVVISRRVYPVKQ
                     VGEIITRQDRRDFSAAEVTRALTRLGFTCRPAEVPAPAVPLTPLENASAMLGTPDDIRP
                     SV"
     gene            1237..1437
                     /locus_tag="ASD51_RS20510"
                     /old_locus_tag="ASD51_08880"
     CDS             1237..1437
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155342.1"
                     /locus_tag="ASD51_RS20510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_08880"
                     /product="hypothetical protein"
                     /protein_id="WP_056793589.1"
                     /transl_table=11
                     /translation="MKSRLTVLGVAVLASVFPAGTVHADETHTDSHNAPQVALIATGQV
                     DDPLEDVLEHATVLGGTQVTG"
     gene            complement(1463..2539)
                     /locus_tag="ASD51_RS20515"
                     /old_locus_tag="ASD51_08885"
     CDS             complement(1463..2539)
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063091.1"
                     /locus_tag="ASD51_RS20515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_08885"
                     /product="acyltransferase family protein"
                     /protein_id="WP_056793269.1"
                     /transl_table=11
                     /translation="MPSLTSRTPGPAPSGAGATDAAPARPGRDPYFDNAKYLAIVLVAM
                     GHSWEPLPDSGRVIETFYTFVYAFHMPVFIMIAGYFSRGFDLRRERVWKLVTSLIVPYA
                     VFEVAYTLFERLTGAPGFPLSPLTPYWLLWFLPALFLWRLTTPVWQTVRWPVAVSLVIA
                     AMGAVSSNIGGDLQLQRVLQFLPFYVLGLQLRPAHFDFVRRRAVRLASVPVCVIALAAA
                     YWAVPRTTTSWFFRRYGAEQLGSPAWTGAVVTLLLFGCAVVLSACFLAWVPSRSMWMTA
                     LGAGTLYGYLLHGFVVKGAIRLDLFEADLVATPLGRILVTVVAAAVVTLLCSPPARRVF
                     RFVVEPRLDWARKPAPAS"
     gene            complement(2629..3537)
                     /locus_tag="ASD51_RS20520"
                     /old_locus_tag="ASD51_08890"
     CDS             complement(2629..3537)
                     /NRPS_PKS="Domain: PKS_ER (19-300). E-value: 8.4e-40.
                     Score: 128.7. Matches aSDomain:
                     nrpspksdomains_ASD51_RS20520_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155344.1"
                     /locus_tag="ASD51_RS20520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_08890"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_056793590.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.4e-18, bitscore:
                     62.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAIQFDHFGGPEVLQPVELAAPVPGPGEVLLTVEAAGVNFADTH
                     QTDGSYLGADALPYVPGSEVVARTPDGRRVLARVSHGYAEQVTAKESALLEIPEDLGAA
                     EALALMVQGLTAWHLLRTSARLRAGETVVVHSAAGGVGSLAVQLAREFGAGRVLAQVSS
                     PDKERLVLDLGADAVVSYPLQEKADVVLDAVGGELFDLALDSLASFGRLVSYGSAARTG
                     FTPVDPARLGRLNAAVVGFWLRPTLAAPGAVDGPLEELFGLVADGRLKPVAGGSYPLTE
                     ARRAHEDMLARRTVGKVVLVP"
     aSDomain        complement(2638..3480)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS20520_PKS_ER.1"
                     /evalue="8.40E-40"
                     /label="ASD51_RS20520_PKS_ER.1"
                     /locus_tag="ASD51_RS20520"
                     /protein_end="300"
                     /protein_start="19"
                     /score="128.7"
                     /tool="antismash"
                     /translation="LAAPVPGPGEVLLTVEAAGVNFADTHQTDGSYLGADALPYVPGSE
                     VVARTPDGRRVLARVSHGYAEQVTAKESALLEIPEDLGAAEALALMVQGLTAWHLLRTS
                     ARLRAGETVVVHSAAGGVGSLAVQLAREFGAGRVLAQVSSPDKERLVLDLGADAVVSYP
                     LQEKADVVLDAVGGELFDLALDSLASFGRLVSYGSAARTGFTPVDPARLGRLNAAVVGF
                     WLRPTLAAPGAVDGPLEELFGLVADGRLKPVAGGSYPLTEARRAHEDMLARRTVGKVVL
                     "
     CDS_motif       complement(3091..3153)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS20520_0001"
                     /evalue="1.80E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="ASD51_RS20520"
                     /protein_end="149"
                     /protein_start="128"
                     /score="23.6"
                     /tool="antismash"
                     /translation="GETVVVHSAAGGVGSLAVQLA"
     misc_feature    complement(3619..3628)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.0"
                     /tool="antismash"
     misc_feature    complement(4173..4188)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.18"
                     /tool="antismash"
     gene            4199..4963
                     /locus_tag="ASD51_RS20525"
                     /old_locus_tag="ASD51_08895"
     CDS             4199..4963
                     /EC_number="1.1.1.47"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-171). E-value: 1.4e-14. Score:
                     46.3. Matches aSDomain:
                     nrpspksdomains_ASD51_RS20525_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155345.1"
                     /locus_tag="ASD51_RS20525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_08895"
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_056793591.1"
                     /sec_met_domain="adh_short (E-value: 1.3e-34, bitscore:
                     114.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 3.9e-34, bitscore:
                     113.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLLNGRVVLVTGASSGIGAAAARVFSQEGATVVLAARREDRLA
                     ALVAELRDKGAEASHVVCDVTVAEDAARAVDFAVNTYGRLDSAFNNAGLGGDRTPLHLM
                     GDDVYDAVMDVNVRGVWNCLRYEIAAMLSNDGGCSIVNTTSVGGLVAIPAAAPYIAAKH
                     AVVGLTRAAADEYAQQGIRVNAVAPGTTRSEITADWFGRNPGLEEMVNSMTPQGRTAEP
                     EEVANAAAWLLSDRCPFLTGTVLPVDGGFVNQ"
     CDS_motif       4223..4318
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD51_RS20525_0001"
                     /evalue="8.20E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ASD51_RS20525"
                     /protein_end="40"
                     /protein_start="8"
                     /score="12.1"
                     /tool="antismash"
                     /translation="VVLVTGASSGIGAAAARVFSQEGATVVLAARR"
     aSDomain        4223..4711
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD51_RS20525_PKS_KR.1"
                     /evalue="1.40E-14"
                     /label="ASD51_RS20525_PKS_KR.1"
                     /locus_tag="ASD51_RS20525"
                     /protein_end="171"
                     /protein_start="8"
                     /score="46.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLVTGASSGIGAAAARVFSQEGATVVLAARREDRLAALVAELRD
                     KGAEASHVVCDVTVAEDAARAVDFAVNTYGRLDSAFNNAGLGGDRTPLHLMGDDVYDAV
                     MDVNVRGVWNCLRYEIAAMLSNDGGCSIVNTTSVGGLVAIPAAAPYIAAKHAVVGLTRA
                     "
     gene            complement(5001..5849)
                     /locus_tag="ASD51_RS20530"
                     /old_locus_tag="ASD51_08900"
     CDS             complement(5001..5849)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047021.1"
                     /locus_tag="ASD51_RS20530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_08900"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_242413214.1"
                     /sec_met_domain="AfsA (E-value: 3.9e-16, bitscore: 54.1,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYVHLRRAEAVLVTGWRRLEDGEFSLTLNWPAPDGGLPYDPRML
                     TQAIRQSGLLIAHAEYGVPLSHHTLLHSFDFTVAPGFRVRSTGPSPLTVGISLAEPKKR
                     GRAVSSLGMDIRLYQDDSLVARADCDFGWISPGAYRRLRGEHLGAGWNTWELPAPADPR
                     TVRRATGTDVVLAPGGRPHHWRLRNDVDNVLLYDHPVDHVPGLVLIEAAHQAANAVLHP
                     ATFEATTVDTSFERYVELDRPCWIEAERAPASGPGGATVLVTGTQDGDTVFRGRLSGPC
                     G"
     misc_feature    5977..5986
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(5977..5990)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.77"
                     /tool="antismash"
     misc_feature    complement(5977..5991)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.68"
                     /tool="antismash"
     misc_feature    complement(5978..5991)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.99"
                     /tool="antismash"
     misc_feature    complement(5979..5992)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.68"
                     /tool="antismash"
     gene            6020..6667
                     /locus_tag="ASD51_RS20535"
                     /old_locus_tag="ASD51_08905"
     CDS             6020..6667
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047020.1"
                     /locus_tag="ASD51_RS20535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_08905"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_056793270.1"
                     /transl_table=11
                     /translation="MARQQRAIRTRRIFLEAAAEVFDEHGYDAATIAAILERAGLTRGA
                     LYFHFTSKEELARGVLEEAVTSDGVTPQTFKLQEWVDIALLLAYRLPREPMLSASIRLS
                     VDPRARSLFGTRWPDWITLGAELLTEAKERGELLPHVDPVATSRLLVGAWTGVQLVTES
                     MADAPDLVTEISALFELILPNNAVPGVLARLDTSPHRAERIIEENRAAAAAS"
     gene            6770..7504
                     /locus_tag="ASD51_RS20540"
                     /old_locus_tag="ASD51_08910"
     CDS             6770..7504
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155348.1"
                     /locus_tag="ASD51_RS20540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_08910"
                     /product="peptidoglycan recognition protein"
                     /protein_id="WP_056793271.1"
                     /transl_table=11
                     /translation="MWLRRTALGAMVVPLAVLVFRDAPVRLVAPEPVLARPVAPSEALR
                     PAIVSRADWHADETLVKEHATYTGAVNAVFVHHTNHANDYDCADAPTMLREMERDHVSG
                     EGWDDIGYNFVVDRCGTIYEGRAGGVGRSVRGAHAKGFNAHSVGVAALGSFGPGVPVPK
                     ALIEGIAKVGAWKLRPGTDPRSTVRMVSTNDESLYQRGEVVHLHAVSGHRDTFQTSCPG
                     DALYDQLPAVRAEMAKLRAPHS"
     gene            7714..8475
                     /locus_tag="ASD51_RS20545"
                     /old_locus_tag="ASD51_08915"
     CDS             7714..8475
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047018.1"
                     /locus_tag="ASD51_RS20545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_08915"
                     /product="transglycosylase family protein"
                     /protein_id="WP_056793272.1"
                     /transl_table=11
                     /translation="MPASPLAKRPVESALVLLLVLLSVLGLSGRSAASVPARAATTQAA
                     SVQVFPARAATAPTVMAPTVTAGTDWDRIAACESNGRWNINTGNGYHGGLQFAPSTWQA
                     YGGGQYAPRADLATRSQQIAVGERVARSQGLSAWPTCGRLGANGTSGPQAGSTPQRSET
                     PKAAPQRRSDSGPSSSQGSSHEASDAAGATDSHELAGTGTYVVQPGDCLSVIADRADVP
                     GGTDALFELNRELLDEGPDLIYPGQRLRLTA"
     gene            complement(9491..9694)
                     /locus_tag="ASD51_RS20550"
                     /old_locus_tag="ASD51_08920"
     CDS             complement(9491..9694)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126199.1"
                     /locus_tag="ASD51_RS20550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_08920"
                     /product="hypothetical protein"
                     /protein_id="WP_056793593.1"
                     /transl_table=11
                     /translation="MVSTKRQTHRQAEYACPACKHTVASVLARHKTLGIFVPLWGPGPC
                     RNPACGRYVPTDEPEPTEHAGH"
     gene            9828..10586
                     /locus_tag="ASD51_RS20555"
                     /old_locus_tag="ASD51_08925"
     CDS             9828..10586
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047017.1"
                     /locus_tag="ASD51_RS20555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_08925"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_056793273.1"
                     /sec_met_domain="HAD_2 (E-value: 2.8e-12, bitscore: 42.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAALSPAAGLRSVRAVVFDTDGVITDSAPVHAAAWKRAFDACLSA
                     HGGQRPFDEGDDYRRHVDGRSRKDGAAAFLKSRGLDLPEGSPDDPPGTETVWAVAARKD
                     EVFTESLRAAPVAVWPGTVRLLHVLREERVPCAAASASRHATELLSGAGLLDLFETVVD
                     GNEARRLELPGKPDPALFVEAARRLGTPAEDTAVVEDALAGVEAGRRGGFGLVVGVDRT
                     HTPAGAADLRHHGADVVVSDPGDLLTGGDD"
     misc_feature    10598..10611
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
ORIGIN
        1 acgccacgac cacggagatc gccgcccgcg agggccgggt gatcatgttc ctggacacca
       61 agcacgcggt ggacaagctg accgaccacc tgctgaacag cggtgtccgg gccgcggcgc
      121 tgcacggcgg caagtcgcag ccgcagcgca cccgcaccct ggaccggttc aagacgggcc
      181 acgtcacggt gctggtcgcc acgaacgtcg ccgcgcgcgg catccacgtc gacaacctgg
      241 acctcgtcgt caacgtcgac ccgccgagcg accacaagga ctacctgcac cgaggcggcc
      301 gtaccgcccg ggccggggag tccggcagcg tcgtcacgct ggtgctgccc aaccagcgcc
      361 gcgagatgac ccgtctgatg gcggacgccg gcatcacccc tcaggtcgct caggtccgct
      421 ccggcgaggc cgagctcagc cgcatcaccg gggcgcaggc gccctcgggc gtccccgtga
      481 ccatcaccgc gccgctgacg gagcgcaagg gcagcggttc gccctcgcgc cggcgaggca
      541 gcaggccccc gcagggccgt cgctccaacg ccaacacggc gacgcccgag gcgcgtgccg
      601 ctgccgctct gcgccggtcc aaccgggccg cgtagtcacc ggacagcagt ccggcagacc
      661 ctttccggct ttctcaccga ccctgttgag gcaccatgcg ctgtgtcatc gcccgcttcc
      721 ccttcgatct gttcaagaac gaagtggagg attcgatgaa gggcatcaag cccgaacccg
      781 tcaccggtga cgcggtggtc atcagccgcc gcgtctaccc cgtcaagcag gtcggggaga
      841 tcatcacccg gcaggaccgc cgcgacttca gcgcggccga ggtgacccgg gcgctgacgc
      901 gtctcggctt cacctgccgt ccggcggagg tgcccgcccc ggcggtgccc ctcaccccgc
      961 tggagaacgc gtccgccatg ctcggcacgc ctgacgacat ccggccgtcc gtctgacgac
     1021 accgcagcgt ccgacgacac cgcacccccg gcgcccccag cgggcccggg ggtgcggtgc
     1081 gtccggacgc gggcctaccg gtcttccgcc gaagccggga atgtctgtaa cagtccctcc
     1141 cgcgcggctc gagtcgtcgg ccccggacac gcccggggcg agatgatcgc cccgctcgcg
     1201 ccgcccggcc cgagcacgaa gagacggggc acccacatga agagcaggct caccgtcctc
     1261 ggcgtggccg tgctggcgtc cgtgtttccg gccgggacgg tccacgccga cgagacccac
     1321 accgactcgc acaacgcgcc ccaggtggcg ctgatcgcga cgggccaggt cgacgatccg
     1381 ctggaggacg tcctggagca cgccacggtc ctcggcggga cgcaggtcac cggctgaggc
     1441 gacgtcctgg gcccgcccgc cctcagcttg ccggggcggg cttcctcgcc cagtcgagcc
     1501 ggggctccac gacgaagcgg aacacccggc gggcgggcgg actgcacagc agggtgacca
     1561 cggcggccgc gaccaccgtc accaggatcc ggccgagcgg cgtcgcgacc aggtccgcct
     1621 cgaagaggtc cagccggatc gcgcccttca cgacgaagcc gtgcagcagg tagccgtaca
     1681 gggtgcccgc tccgagggcg gtcatccaca tactgcggct cggaacccag gcgaggaagc
     1741 aggcgctgag caccacggcg cagccgaaca gcagcagggt cacgaccgca cccgtccagg
     1801 cgggcgagcc gagctgctcg gcgccgtacc ggcggaagaa ccacgaggtc gtcgtgcgcg
     1861 ggaccgccca gtacgccgcg gccagggcga tcacgcagac cgggacggag gcgaggcgca
     1921 ccgcacggcg tcgtacgaag tcgaagtgcg ccggccgcag ctgcagtccc agcacgtaga
     1981 acggcaggaa ctgcagtacc cgctgaagct gcagatcgcc gccgatgttg ctgctgaccg
     2041 cccccatggc cgcgatgacc agggacaccg cgacgggcca ccggaccgtc tgccagaccg
     2101 gtgtcgtgag acgccagagg aagagcgcgg gcaggaacca cagcagccag tacggggtga
     2161 gcgggctcag cgggaagccg ggggctccgg tgaggcgctc gaagagcgtg taggccacct
     2221 cgaagacggc gtagggcacg atcaggctgg tgacgagctt ccacacccgc tcgcgccgca
     2281 ggtcgaaacc gcgggagaag tagccggcga tcatgatgaa gacgggcatg tggaaggcgt
     2341 agacgaaggt gtagaacgtc tcgatcacgc gtccgctgtc gggcagcggc tcccaggagt
     2401 gccccatcgc gacgaggacg atggccaggt acttcgcgtt gtcgaagtac gggtcgcggc
     2461 cggggcgggc cggggccgcg tccgtggctc cggcccctga gggggccggt cccggggtgc
     2521 gtgaggtcag ggatggcatc aggccaccct aatgacctcc cgcacgcatg cggaccccgt
     2581 gcgggacccg gctcgcggtc cttcccgcac cccctgcctg gggccggctc aggggacgag
     2641 gaccaccttg ccgaccgtcc ggcgggccag catgtcctcg tgggcgcggc gtgcctcggt
     2701 gagcgggtag ctgccgcccg ccaccggctt gagccgcccg tcggcgacca ggccgaagag
     2761 ttcctcgagg ggcccgtcca ccgcgcccgg cgccgccagg gtggggcgta gccagaaccc
     2821 caccacggcg gcgttgagcc gccccagccg ggccgggtcg accggcgtga aaccggtccg
     2881 ggcggcgctg ccgtaggaca cgagccggcc gaaggacgcc agggagtcca gtgccaggtc
     2941 gaacagctca ccgccgacgg cgtccaggac gacgtccgcc ttctcctgga gcgggtagct
     3001 gacgactgcg tccgccccga ggtccaggac gagccgttcc ttgtccgggg aggagacctg
     3061 ggcgagcacc cggcccgctc cgaactccct ggccagctgt acggcgaggc tgcccactcc
     3121 gcccgccgcg gagtgcacca cgacggtctc gccggcccgc agccgggcgg aggtccgcag
     3181 cagatgccag gcggtcagcc cctgcaccat cagggcgagc gcctcggcgg cgccgaggtc
     3241 ctcggggatc tccagcaggg cggactcctt ggcggtgacc tgctccgcgt atccgtgcga
     3301 gacccgggcg agcacccgcc tgccgtcggg ggtgcgggcc accacctcgc tgccggggac
     3361 gtacggcagg gcgtcggccc ccaggtagga accgtccgtc tggtgggtgt ccgcgaagtt
     3421 caccccggcg gcctcgacgg tgagcagcac ctcaccgggg cccgggacgg gggcggccag
     3481 ttccacgggc tggaggacct cggggccacc gaagtggtcg aactggatag cgatcatgtc
     3541 gcacggtatc gcgggggccc ggtgacgtcc gggcatcgcg gaatccgtcg gggtcggggc
     3601 ccgggccccg gggaagggca aaaaaacaat acaaccggtt tgtttggaac gtcaccctgc
     3661 gtcgttgccg gccggtaccg aacgggcagc ggcacccgaa gtccccggat cccccgcacg
     3721 caccggagtg gcgggccggc ccggcaggac cgcgcggtac gcacgcgccg ggagctgctc
     3781 cgcccggccg ccggggtatt cgacctggga ggtttcccgc tcccctcgct caccggtagc
     3841 gccgccgggg cggggtcggc agtggggcgc cgcacttcca cttccccgac gggcgcgcgc
     3901 tgaagtcggc cgccggggga cgcggcgcgc gtcctccgga acgacctcgc cccgccctcc
     3961 ggcggacggc tcttcccgct gcgacacctg gtggaccccg cacacgcacc ggccccgggc
     4021 gttcccccgg agggcgtggt ggtccaccgt gacggcggcg gtcgcggggg tgcgggccct
     4081 cggccgtctc gacgcggagc ggtccccgca gtacccggtc ccccggttct ggaagctgct
     4141 gctgccacgg atctccgcag gcatggtccc gttcgaacag gcctgccaga ctgcgcccat
     4201 gagtgatctt ctgaacggca gagtcgtcct cgtcaccggg gcgagcagcg gcatcggcgc
     4261 ggctgcggcc cgggtgttct cccaggaggg cgcgacggtg gtcctcgccg cgcgccggga
     4321 ggaccgactg gccgcgctgg tggccgagtt gcgggacaag ggtgcggagg cgtcccacgt
     4381 ggtctgtgac gtcaccgtgg cggaggacgc cgcccgggcg gtggacttcg cggtgaacac
     4441 gtacgggcgc ctggactcgg cgttcaacaa cgcggggctc ggcggcgacc ggactcccct
     4501 gcacctgatg ggcgatgacg tctacgacgc cgtcatggac gtcaacgtgc gcggtgtctg
     4561 gaactgtctc cggtacgaga tagcggccat gctgtcgaac gacgggggct gctccatcgt
     4621 gaacaccacc agcgtgggcg gcctggtggc catacccgcc gccgcgccct acatagcggc
     4681 caagcacgcg gtcgtcggcc tgacgcgggc cgccgccgac gagtacgcgc aacagggcat
     4741 cagggtgaac gccgtggccc cgggcaccac gcgcagtgag atcaccgccg actggttcgg
     4801 gcgcaatccg ggcctggagg agatggtcaa cagcatgacg ccgcagggcc gtacggccga
     4861 gcccgaggaa gtggccaacg cggcggcctg gctgctcagt gaccgctgcc cgttcctcac
     4921 gggaaccgtc ctgccggtgg acggcggctt cgtcaaccag tgagccgccg cacgcgcggg
     4981 cggtgactcc gcgggggctc tcagccgcac ggaccgctca gccggccccg gaagaccgta
     5041 tcgccgtcct gcgtccccgt gaccagcacc gtggctcctc cggggccgga ggcgggcgcc
     5101 cgctccgcct cgatccagca ggggcggtcg agctcgacgt accgctcgaa ggacgtgtcg
     5161 acggtggtgg cctcgaaggt ggcggggtgc aggacggcgt tggccgcctg gtgggcggcc
     5221 tcgatcagga cgagtcccgg gacgtggtcg acggggtggt cgtacagcag gacgttgtcc
     5281 acgtcgttgc gcaaccgcca gtggtggggc cgcccgcccg gtgccaggac cacatcggtg
     5341 ccggtcgccc gccggacggt gcgcgggtcg gccggtgcgg ggagctccca ggtgttccag
     5401 ccggcgccga ggtgctcgcc ccggagcctg cggtaggcgc cgggggatat ccagccgaag
     5461 tcgcagtccg cccgcgccac caggctgtca tcctggtaga ggcggatgtc catgccgagg
     5521 gaactcacgg ccctgccacg cttcttcggc tcggcgaggg agatcccgac ggtcagcggg
     5581 gacggcccgg tcgaccgaac ccggaacccg ggggctacgg tgaagtcgaa ggagtgcagc
     5641 agggtgtggt gggaaagcgg gacgccgtac tccgcgtgcg cgatgagcag gccgctctgc
     5701 cggatggcct gggtgagcat ccgggggtcg tagggcagtc cgccatcggg cgcgggccag
     5761 ttgagggtga gcgagaattc gccatcttcg aggcggcgcc atccggtgac gagaacggct
     5821 tcagcacgtc tgaggtgcac gtattccata cggacaccct cactgccccc gacgtcggcg
     5881 cgcggagtgt gagggaaaac aggtacgtcg ggcacggtcc ccccggacat ggcgcaaagt
     5941 gggcagcctg gcgctgatat aataccggtt caccggtctt ttttgaagaa gcgtcaagcc
     6001 gaggtcaagg gagcgcgagt tggcaagaca gcaacgggcg atccggacgc gcagaatctt
     6061 cctcgaggcc gctgcggagg tcttcgacga gcacggttac gacgctgcca cgatcgccgc
     6121 gatcctggag agggccggcc tcacgagggg tgcgctctac ttccacttca cctccaagga
     6181 ggagctggcg aggggcgtcc tcgaagaggc cgtgacctcg gacggcgtga ctccgcagac
     6241 gttcaagctg caggagtggg tggacatcgc gctcctgctg gcctaccggc tgccccgtga
     6301 acccatgctc agcgcctcga tacggctgtc cgtcgacccc cgggcccgga gcctgttcgg
     6361 gacccgctgg ccggactgga tcacgctggg ggcggagctg ctcaccgagg ccaaggagcg
     6421 gggcgagctg ctgccgcacg tcgacccggt cgccacgtcc cggctcctcg tcggcgcgtg
     6481 gaccggtgtg cagctggtga cggagtcgat ggcggacgcc ccggacctgg tcacggagat
     6541 ctccgcgctc ttcgagctca tcctccccaa caacgccgtc cccggtgtgc tggcccggct
     6601 cgacacctcc ccgcaccgcg ccgagcgcat catcgaggag aacagggccg ccgccgccgc
     6661 gtcctgaccc ccgcatgccg cgcgggaggg cttccggccc gccggcacgc ttcacccgac
     6721 cgggtgcggc gcgactgcga cgtcgctggt cagcggtcag gctggcccca tgtggcttcg
     6781 ccgaacagcc ctgggcgcca tggtcgtgcc gctggccgtc ctggtgttcc gggacgcgcc
     6841 ggtccggctc gtcgcgcccg agccggtcct ggcccggccc gtggcgccgt ccgaagccct
     6901 ccggcccgcg atcgtcagcc gggccgactg gcacgcggac gagaccctgg tcaaggagca
     6961 cgcgacgtac acgggggcgg tgaacgcggt cttcgtccac cacaccaacc acgccaacga
     7021 ctacgactgc gccgacgccc cgacgatgct gcgggagatg gagcgggacc acgtctcggg
     7081 tgagggatgg gacgacatcg gatacaactt cgtcgtcgac cgctgcggga cgatctacga
     7141 gggcagggcg ggcggggtgg ggcgctcggt gcgcggggcg cacgccaagg gcttcaacgc
     7201 gcacagcgtg ggcgtcgcgg cactcggcag cttcggcccc ggggtcccgg tgccgaaggc
     7261 gctcatcgag gggatcgcga aggtgggcgc gtggaagctg cggccgggca cggacccgcg
     7321 gagcaccgta cggatggtct cgacgaacga cgagagcctg taccagcggg gtgaggtggt
     7381 ccacctccac gcggtgtccg gccaccgcga caccttccag accagctgcc ccggggatgc
     7441 gctgtacgac caactgcccg ccgtccgggc ggagatggcc aagctgcggg ctccgcacag
     7501 ctgacctgcg ccggaccggg gcatccgcgg agccggcctc ggccgaccct tcgggcccgt
     7561 ccccgcccgc atcggccggg tggccgggcc gtggccccca cgcgggtgaa catgcggccg
     7621 cggaacgcgt cggagcccct tgaaaagcat atcggcggct tgtctgttcg tgcccttgca
     7681 acagttcccg gagcacagcg gaggaagacc gtcatgccgg catcacccct cgccaagcga
     7741 cccgtcgaat cggcgctcgt ccttctgctg gtcctcctga gcgtgctggg cctctccggc
     7801 cgcagtgccg cgtccgtccc cgcccgggca gccaccactc aggccgcctc cgtccaggtg
     7861 ttccccgccc gggccgccac ggcgccgacc gtcatggcgc cgaccgtcac ggcgggcacc
     7921 gactgggacc gcatcgccgc ctgcgagagc aacggccgct ggaacatcaa caccggcaac
     7981 ggctaccacg gcggactgca gttcgcaccc tccacctggc aggcgtacgg cggtgggcag
     8041 tacgcaccgc gcgccgacct cgccacccgg tcccagcaga tcgccgtcgg tgagcgcgtc
     8101 gcccgttcgc agggactgtc cgcctggccc acctgcggcc ggctcggtgc gaacggcaca
     8161 tcgggcccgc aggcgggcag caccccccag cggagcgaga cgccgaaggc cgcaccgcag
     8221 cgccggtcgg acagcggtcc gagcagctcg cagggctcct cccacgaggc gtccgacgcg
     8281 gccggggcga ccgactccca cgagctcgcc ggcaccggga cctacgtcgt ccagccgggc
     8341 gactgcctct ccgtgatcgc cgatcgcgcg gacgtacccg gcggcaccga cgcgctgttc
     8401 gagctgaacc gtgagctgct ggacgaggga ccggacctga tctaccccgg ccagcgcctc
     8461 cgtctcacgg cctgaaccgc acggtccggg cagacgtggc cgcagcccgt cgcgtgcgag
     8521 gccatggtgc cgaaaggtac gtccgtggtg tggatcccga accgcaccgg gcaggagaag
     8581 cgtgaagcgt gacagggccg gaatccagga agcaccgcgt cacccggacg cagccggtga
     8641 cgacgaccac ctcgtcgcgc cggtcccccc tcggcccgag cagaatccga acggctttcc
     8701 cgcagtgacc cgaggccgct tccccgggag cgtggctgta ggccccgtcc atgaacagca
     8761 cggcatggca gcactttcgg aagactccct cggtgcgccg ctcggtgtgg ccggcccgca
     8821 gggccgcgcg cgtcaccccg acgagctgca ccccgggcag caggcaccac agcacgtgca
     8881 gcagtccggc gccgagccgg acgaccgtgg ccacgcccct gccggggtgg ccccgaagtg
     8941 gaccggaagg tggcccacct ccggggtggg cggacaagcg gcgcaccccg ccgggacggg
     9001 acgaggagga atcccggggc gtcgatcccg cgcccgaccg accgagccgg agtcggctac
     9061 cgcgcccgac gaaggggaag tcctcgggat cccggcgccc gtgccgggtc acgttcccgt
     9121 gtgacagtga cgacgacaga ccgcgccacg gcgggtccgg tcgtgctgat cgatggaggg
     9181 gccgatcgat ggaagggctg acggctcgat ggcgcgagtg aagcggagcg gtccgagtcc
     9241 ggaggtgggg gaggagccga ttccgtcggt gtgagcggga cgcggggaga ggggcaccgc
     9301 gacggcgatc ccccacggcc gggacatagg gcactccggc agccggatca acgccgcgcg
     9361 tgcgaggacg gcaggcgcag ggacgtggca agggcctcga cgggtcctgc gcgcggcgcc
     9421 ccggccgtgc gccgtgcccc tgccctgctc cggcgggcac tgaccgtgcc cggcgcccgg
     9481 tgtccggggc tcagtgtccc gcgtgttccg tcggctcggg ctcgtccgtc ggcacgtacc
     9541 tgccgcaggc ggggttccgg cacgggccgg ggccccagag gggtacgaag atgccgaggg
     9601 tcttgtgccg tgccaacacg gacgcgacgg tgtgcttgca ggcgggacac gcgtactccg
     9661 cctgccgatg cgtctggcgc ttggtactga ccatgtactc acggtagccc aaacgtgtgc
     9721 agaacgagac atttagtttt ctttggtgag gctccaggaa aggcgctcgc cgccggaacc
     9781 tggtgccatg gaacggggga cccacccgag gaagggacca cccggtcatg gcagcactct
     9841 ccccggccgc gggcctgcgc tccgtgcgtg ccgtggtctt cgacacggac ggggtgatca
     9901 ccgactccgc gccggtgcac gccgcggcgt ggaagagggc gttcgacgcc tgcctgtcgg
     9961 cccatggggg ccaacgtccc ttcgacgagg gggacgacta ccgccgccac gtcgacggcc
    10021 ggtcgaggaa ggacggcgcg gccgccttcc tgaagtcgcg cgggctggac ctccccgaag
    10081 gcagtcccga cgacccgccg ggcacggaga cggtgtgggc ggtcgccgcc cgcaaggacg
    10141 aggtgttcac ggaaagcctg cgcgccgccc cggtcgccgt ctggccgggc acggtccgcc
    10201 tcctgcacgt gctgcgcgag gagagggtgc cgtgcgccgc cgcctccgcc tcccggcacg
    10261 cgacggaact gctctccggg gccggtctcc tggacctctt cgagaccgtg gtcgacggca
    10321 acgaggcgcg ccggctggaa ctgccgggca aaccggatcc cgccctgttc gtggaggcgg
    10381 cccgacggct gggcaccccc gccgaggaca ccgccgtcgt ggaggacgcg ctggccggag
    10441 tggaggcggg ccgccgcggc gggttcgggc tggtcgtcgg cgtcgaccgc acgcacaccc
    10501 cggccggtgc cgccgacctt cgccaccatg gtgccgacgt cgtggtgtcc gatccggggg
    10561 atctgctgac cggcggggac gactgatggc gagggcctgg acctggtcct acgaggggta
    10621 cgacccggcg aaggagcgcc tgcgcgaggc gctgtgcacc ctgggcaacg gctacttcgc
    10681 caccagaggg gccgcgtccg agacaccggc gggcggaccg cactacccgg gcacctatgt
    10741 ggcgggctgc tacaaccggc tgacctcctc ggtccaggac cagcaggtcg agaacgagga
    10801 catggtcaac ctccccgact ggctgccgct gcgctaccgc atccacccg
//
