LOCUS       NZ_LMFT01000004        21056 bp    DNA     linear   CON 07-JUN-2024
DEFINITION  Streptomyces sp. Root55 contig_12, whole genome shotgun sequence.
ACCESSION   NZ_LMFT01000004
VERSION     NZ_LMFT01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root55
  ORGANISM  Streptomyces sp. Root55
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 288724)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 288724)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140605
            Assembly Name                     :: Root55
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001427245.1-RS_2024_06_07
            Annotation Date                   :: 06/07/2024 01:50:20
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,084
            CDSs (total)                      :: 7,008
            Genes (coding)                    :: 6,730
            CDSs (with protein)               :: 6,730
            Genes (RNA)                       :: 76
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1 (5S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 278
            CDSs (without protein)            :: 278
            Pseudo Genes (ambiguous residues) :: 0 of 278
            Pseudo Genes (frameshifted)       :: 105 of 278
            Pseudo Genes (incomplete)         :: 225 of 278
            Pseudo Genes (internal stop)      :: 24 of 278
            Pseudo Genes (multiple problems)  :: 67 of 278
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 19:11:06
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 29743
            Orig. end                         :: 50799
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMFT01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21056
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21056
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21056
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11056](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11056)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    complement(270..284)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            complement(355..813)
                     /locus_tag="ASD51_RS34650"
                     /old_locus_tag="ASD51_26080"
     CDS             complement(355..813)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327697.1"
                     /locus_tag="ASD51_RS34650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26080"
                     /product="Fic family protein"
                     /protein_id="WP_242424363.1"
                     /transl_table=11
                     /translation="MAFADAEQGRPLTFALMKRWQRTVLSHGLVGFRTMPAFAKGGRER
                     YGLAPDTRARFERCLSESAQPDLPLPSRAARTYLDVLFFHPFEDGNARAAMLALAFVLA
                     REGVLLDQVHPLQTTRWADDAEGAADLAVLLGILITAAQRRLSHRRQS"
     gene            complement(1008..1679)
                     /locus_tag="ASD51_RS07605"
                     /old_locus_tag="ASD51_26085"
     CDS             complement(1008..1679)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972609.1"
                     /locus_tag="ASD51_RS07605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26085"
                     /product="hypothetical protein"
                     /protein_id="WP_242424364.1"
                     /transl_table=11
                     /translation="MSELWAHTLTWADVDPACHPFEMDADAAKELACLVVPLLPSCEVA
                     REDRRRSLDPATEFLAGRYGRWACGWNWSVGEGDVDGGIVEVWCCSSDSVTTPGATAPL
                     VVEALREWRDWLEDLAERFAALAPPENTPVSSTDLWYWERACTRLVTVVADRTQAESGW
                     YGHCMQVLQWFLAYNGIDEGQAVEIVRNAVGGRFGSWIAPDVPVVDAVSSRFARGAGGI
                     R"
     gene            <1758..>2057
                     /locus_tag="ASD51_RS34655"
                     /pseudo=""
     CDS             1758..>2057
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009188870.1"
                     /locus_tag="ASD51_RS34655"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLVAEQSDNYWYSNNHQVVIDADTRLVVVVGQPLTGHRDARKAWE
                     ESGAKAAAGRTLTTADGGYPGTGLLMPHLRRKGEDLPDWREAHNKSRKQVRARVE"
     misc_feature    complement(2599..2612)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.22"
                     /tool="antismash"
     misc_feature    complement(2620..2635)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.96"
                     /tool="antismash"
     misc_feature    complement(2621..2635)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.34"
                     /tool="antismash"
     misc_feature    2622..2633
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.41"
                     /tool="antismash"
     gene            2645..3169
                     /locus_tag="ASD51_RS07610"
                     /old_locus_tag="ASD51_26090"
     CDS             2645..3169
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007490436.1"
                     /locus_tag="ASD51_RS07610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26090"
                     /product="hypothetical protein"
                     /protein_id="WP_056788408.1"
                     /transl_table=11
                     /translation="MNIARALTATAATAALVAGATVLATGTASAASYKCTTSKKSVDHP
                     GNTVNDNFNFSVKTCAKREGGYIYTKAYVSVDGPWGFAGSSSVNDARALIQVKRSVSGT
                     DPVSKYAYGNGLGSKLNNLDAYGNTSYTSPTVKHKAAAGSRYLGDSVMQIDWRNDGKGR
                     ISYNFSASPTV"
     gene            complement(3985..4182)
                     /locus_tag="ASD51_RS07615"
                     /old_locus_tag="ASD51_26095"
     CDS             complement(3985..4182)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASD51_RS07615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ASD51_26095"
                     /product="hypothetical protein"
                     /protein_id="WP_056788411.1"
                     /transl_table=11
                     /translation="MLNLFTLKDGKIIERRAQKRRVVLDLPGDGGGGSVWLSTSTDITG
                     TPSSGAVSTASARRLPGRGW"
     misc_feature    complement(4244..4258)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.7"
                     /tool="antismash"
     gene            4296..4991
                     /locus_tag="ASD51_RS07620"
                     /old_locus_tag="ASD51_26100"
     CDS             4296..4991
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049508.1"
                     /locus_tag="ASD51_RS07620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26100"
                     /product="hypothetical protein"
                     /protein_id="WP_056788414.1"
                     /transl_table=11
                     /translation="MTDDQTLTPVTVTLEAGPTGAGSIDDLELFYARRALNRFRTLLGR
                     QGLLDLLAADIEEGNAFLRESARTSDGSFKAGTTVLATRGLSSGTFLAWMDEAFAGDES
                     ALLAAHPEHYVMGTDAIGARVVENIGPHVASFYMGGWGTDALGWAADADELLPESEFPR
                     KMSSNLFLADGTVVGRSLIQFGDTADGFTAHLTVYFPVTCPDEVLDHHLRHYAVEFRNW
                     IEAAAAARA"
     gene            complement(5490..6629)
                     /locus_tag="ASD51_RS07625"
                     /old_locus_tag="ASD51_26105"
     CDS             complement(5490..6629)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153084.1"
                     /locus_tag="ASD51_RS07625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26105"
                     /product="FUSC family protein"
                     /protein_id="WP_056789073.1"
                     /transl_table=11
                     /translation="MTVWRHTGYELDAVRRSASRALRHSGPERATAVQALKAAGAAMLA
                     WALAAFWIESPMALMAPWTALILVDTTVYRSLRAGVQQLAIISLGAVWASVAMYLTDGS
                     TLHAMAISLPPLTLIAAYQRLGPHGIYGATTALFVIAYGSYQPGEIGHRLLETFIGAAI
                     GLSVNAFVLPPLRLHDVRSNLHALALECSGLLRAIADGLTQPWGAAEAEAWEDRARRLR
                     CGVEAVAVARRRSAESTRLNPARRLRRAHFVPHPPPQADHQWENVVHHLTALTRTMSGI
                     AARSHALSAPTGSFTRDYAALAGDLARLCSDRAEALARFEEHGTTPRETAVAAWERYEQ
                     LLGRLHSQADNSATAVGGGLLIEIRQLLVALAPEEPGPP"
     misc_feature    complement(6291..6293)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6857..7207)
                     /locus_tag="ASD51_RS07630"
                     /old_locus_tag="ASD51_26110"
     CDS             complement(6857..7207)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446395.1"
                     /locus_tag="ASD51_RS07630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26110"
                     /product="hypothetical protein"
                     /protein_id="WP_056789078.1"
                     /transl_table=11
                     /translation="MLSHRREHDVLVLTVREDPGINGRAELATRIMDFTQAYQPSPVLV
                     VINDGAASPATASAVLRAHRQCSDLNVLFSVATHDAPVRRLLEDNADSRGARLVVHPRV
                     DVALESAYAAAA"
     misc_feature    7176..7190
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            <7598..>7726
                     /locus_tag="ASD51_RS37575"
                     /pseudo=""
     CDS             7598..>7726
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003887303.1"
                     /locus_tag="ASD51_RS37575"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS630 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIVETLEQRPKNATHRSTRSMAAATGMSQSAISRIWRAFGLAP"
     gene            7872..8477
                     /locus_tag="ASD51_RS07635"
                     /old_locus_tag="ASD51_26115"
     CDS             7872..8477
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020554030.1"
                     /locus_tag="ASD51_RS07635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26115"
                     /product="HD domain-containing protein"
                     /protein_id="WP_056788417.1"
                     /transl_table=11
                     /translation="MLVEVAGVRVPIGRAAEAARTVCVEYADDALYHHSVRSYFFGAAW
                     AEARGLDFDRELFFVAAMLHDLALTPPFDSHTLAFEEAGGHLARVFTAGLGWPVERRDR
                     VADLIVLHMRDDIAPEVDVESRLLQVGTSADVSGTGLEAFGISFTDTLVSAYPRLGFAR
                     SFVRLFQDQAERKPGCAASELAAGEWAERTLSHPLDQG"
     gene            complement(8733..9902)
                     /locus_tag="ASD51_RS07640"
                     /old_locus_tag="ASD51_26120"
     CDS             complement(8733..9902)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240938.1"
                     /locus_tag="ASD51_RS07640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26120"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_056788418.1"
                     /transl_table=11
                     /translation="MTYTETSLDALRRSGDELADATVAALFERGEVGKFNTLMRYVSTA
                     GAPLPDGLPDVAREYLSATSAPPAWVDWEEMEKARLFFIDNNVHISTALSFASMPACYV
                     VPHVAKLLSATHGLSYPSKRMAETGQFTVYLMQPDAFETGSRFIPAAQKVRLLHASIRH
                     HLRREDRWDTGALGTPICQEDLIGGQMFFSLVVLDSLHRLGIHMSAVGADAYYYAWRVV
                     GAMLGVDQDAVPKSLDEARQFLDLYMLRHMGPSEEGAHLTRQLIDLYEEVVPGTFFDPV
                     VSALIRYLVGDTCADWLQVPRTTWDTVVGAMPHVLGVMEAIEDRSPLAARALDRIGHLT
                     TLFELSSLTRGRVMHYAVPEELRKDFGITDTAPRTSRWVPPPATVSSGH"
     gene            complement(10001..11056)
                     /locus_tag="ASD51_RS07645"
                     /old_locus_tag="ASD51_26125"
     CDS             complement(10001..11056)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956355.1"
                     /locus_tag="ASD51_RS07645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26125"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_056788421.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.2e-37, bitscore:
                     122.7, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASDRWEPVAFKARVDDVLHRFVAQEADRFTEIDAALGPVAEQLE
                     AAVADGKRLRAAFCYWGWRAVGQPDNDALVRAAASMELVHAAAVVHDDLIDDSPLRHGR
                     PTAHMALRSALRRRPRAAGAARSLAMLVGDLLMGLAGQLFATSGLPAAYLARARPLWSV
                     LTRELVAGECLEILRTGADPDLTDSLKVIRYKTAKYTVEQPLLIGGALAGAGERLREGY
                     TAYGLPLGEAFQLRDDLLGLFGSPGTTGKANADDLRGRRPTALLAETWRVAGEGERRQL
                     RTILGRRDVGEDGLHTVREMMRRLHAPDRIEEMITVRVDEALDALHAVDVPAPATHALT
                     ALARSVTVRLS"
     gene            complement(11046..11324)
                     /locus_tag="ASD51_RS07650"
                     /old_locus_tag="ASD51_26130"
     CDS             complement(11046..11324)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330752.1"
                     /locus_tag="ASD51_RS07650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26130"
                     /product="hypothetical protein"
                     /protein_id="WP_056788424.1"
                     /transl_table=11
                     /translation="MTQDARDGGGPEAQVVLLLAGLADLAVSTVGSALGTMRGLLRRSD
                     TAELAAGAEHDLLARGRLVLDRYATAPPAHLEVLARESLARKAAGGE"
     gene            complement(11965..13443)
                     /locus_tag="ASD51_RS07655"
                     /old_locus_tag="ASD51_26135"
     CDS             complement(11965..13443)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512504.1"
                     /locus_tag="ASD51_RS07655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26135"
                     /product="PepSY-associated TM helix domain-containing
                     protein"
                     /protein_id="WP_056788427.1"
                     /transl_table=11
                     /translation="MSPRIEELPQNDHDPTGAAPDRTTSAGPVSEHLGPVRSWAGLRHL
                     LVRLHFYAGVLVAPFLLVAALTGLAYTLAPQLDALVYGDQLRVEHVGGETRPLAEQIAA
                     ARSAHPEGTTMSVTTPPGPEDTTRVVLSVPELGDKQRTVFVDPYTAEVQGELTTWFGST
                     PLTTWLDDLHRNLHLGETGRLYSEVAASWLWVIVAGGLVLWLGRSRGRRAKSARGVLLP
                     DRTAGGVRRTRSWHAATGVWLALGLLFLSATGLTWSQHAGERFGQALDATNGRAPALDT
                     ALPGGDAPAGDHAEHAEHGGSGGEAGDADPAAFAAALTAARGAGLDGTVEVTPPADPAS
                     AWVVAQTDNVWPVHYDQVAVDTTTGEVVSHNRWAGYPVLAKLSKLGVQGHMGVLFGIVN
                     QIVLAVIALGLTAVIIWGYRMWWQRRPTRTDRTALAGKAPERGAWRRLPLTALVLGIPA
                     VAALCWALPVLGVTLIGFLMVDAMLGAARRIRTT"
     misc_feature    complement(13969..13984)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            complement(13970..15388)
                     /locus_tag="ASD51_RS07660"
                     /old_locus_tag="ASD51_26140"
     CDS             complement(13970..15388)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003949908.1"
                     /locus_tag="ASD51_RS07660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26140"
                     /product="hypothetical protein"
                     /protein_id="WP_056788429.1"
                     /transl_table=11
                     /translation="MKTEERSDSTRPAEEFAPPAGRRDRRPDLAAAAVGLLLVAAASAV
                     GWAVQNANGSLQVHWPPLLATWDPHVGPGTPAAVAVAAAVVAYGPGLAERLPWRRLLVA
                     AWAASLAWILSLALIEGWDRGVARRLTTKHEYLRVIDRFEDVPSALRGFTDHIVIGPPG
                     NWPAHVAGHPPGATLTFVGLDRIGLGGGAWAGVWCIVLGASGVMAVLIAVRALAGERLA
                     RGAAPFLVLAPFAVWTGTSADGYFAGVAAWSIALLALAATARTRLARYAAPGSGVLFGL
                     TCYLSYGLTLIGVLLCAVLLLARTARPVLPFLAGALVAPVAFTVAGFSWWEAYHLLVER
                     YYQGAGGVRPYSYWVWGNLACATLAAGLATVAGLRRAVVAAPGGVRSLLPARGGGAVTG
                     GTCLALLVLAALLAIAAADLSGMSKAETERIWQPFLLWLLPATALLPRRDHRGWLAAQA
                     ILALLINHLLWTGW"
     misc_feature    complement(15440..15455)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.78"
                     /tool="antismash"
     gene            15532..16800
                     /locus_tag="ASD51_RS07665"
                     /old_locus_tag="ASD51_26145"
     CDS             15532..16800
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514010.1"
                     /locus_tag="ASD51_RS07665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26145"
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_056788431.1"
                     /transl_table=11
                     /translation="MDDSRLKTRARLAAPQLPSTPAFWRSPVRGVRFTAVLGVVLLAGI
                     TLLFVTGLLSYAAYNPDLAAVNDKTPDKGLLGFYLFAWPTGPHWLYRLTQGLHVTVGIV
                     LVPVLLAKLWSVVPKLFVMPPARSVAQALERVSLLLLVGGVLFEFVTGLLNIQLEYLFP
                     GSFYPLHFYGAWVFVAGFVAHVGLKLPRTLRVLRHGIPPAADELATPDPAPPTLSRRGA
                     LTVVGAGSLLLLVTSAGRSFDGPLRRVALLTPRGGAEPGEGPNGFQINKTAAKAGIVPA
                     DTRERWRLTLAGPAGEVRLTRAQLLAMPQHSAALPIACVEGWSTSDQWWRGVRLRDLAA
                     LAGHADGRAPDVLVESLQPSGPFRTVALRGNQVADPRSLLAFGVNGEELSLDHGYPARI
                     VVPAAPGVMNTKWVARMTFGGVR"
     gene            complement(17111..17896)
                     /locus_tag="ASD51_RS07670"
                     /old_locus_tag="ASD51_26150"
     CDS             complement(17111..17896)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018893847.1"
                     /locus_tag="ASD51_RS07670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26150"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_056788433.1"
                     /transl_table=11
                     /translation="MSTTLPPTGPPLPTAWAADPYANALRTGRGPLFLRRADGWLLPLD
                     VERWCADADAADLSALRRCEGPVVDIGCGPGRLVAALAAHGHRALGIDVSEAAVAHTRR
                     LGGSALRRSVFDQLPDEGRWGTALLLDGNLGIGGDPGALLRRTAALLAPGGLLLAETAP
                     EDVDERVQVRLDDGREPAVPGPPFPWARLGRPALLRYARLCGWRPTDQWEADGRPFVTL
                     RLDRTVRTTSQSADSVNSAAVIRSQFPRNLSGDIPAAGS"
     gene            complement(17893..18537)
                     /locus_tag="ASD51_RS07675"
                     /old_locus_tag="ASD51_26155"
     CDS             complement(17893..18537)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018523187.1"
                     /locus_tag="ASD51_RS07675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26155"
                     /product="DUF2064 domain-containing protein"
                     /protein_id="WP_056788435.1"
                     /transl_table=11
                     /translation="MTPGPTTLLVLAKEPVPGRVKTRLTPPFTPDEAAELAAASLADTL
                     RQVRTLPARRRILVLDGRPGPWLPPGIEVRPQCAGGLDERIAGAFAECTGPALLIGMDT
                     PQLTAAHLAPALSPGGWDECDAWFGPAEDGGFWALGLAEPRPELVLGIPMSLPHTGGVQ
                     RARLTDAGLTVGDLPELRDVDEADDAWHVAQAAPHGEFAATLARLTRTAVG"
     gene            complement(18534..19268)
                     /locus_tag="ASD51_RS07680"
                     /old_locus_tag="ASD51_26160"
     CDS             complement(18534..19268)
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382142.1"
                     /locus_tag="ASD51_RS07680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26160"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_107103212.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 6.1e-21,
                     bitscore: 69.1, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDSSAELTAPVTADIVLPCLDEAAALPWVLGRIPDGWRAVVVDN
                     GSTDGSADIARAWGATVVHEARRGFGAACHAGLLAATAPYVCFCDCDGSLDPALLPGLV
                     ARVAAGESDLVLGRRCPERFGAWPAHARAGNFALSRMLRTRTGLRLRDLGPMRAARREA
                     LLALDLTDRRSGYPLEMVVRASDAGLRVTETDVPYLARTGRSKVTGTWRGTWHAVRDMR
                     AVLRRPPGVPTGTGSVGAGTCR"
     gene            19392..20231
                     /locus_tag="ASD51_RS07685"
                     /old_locus_tag="ASD51_26165"
     CDS             19392..20231
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018099805.1"
                     /locus_tag="ASD51_RS07685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD51_26165"
                     /product="response regulator transcription factor"
                     /protein_id="WP_079100676.1"
                     /transl_table=11
                     /translation="MQNSPFEPAPGPAAHALSGPAPGACPDGPARVPEPDPARGSGPRG
                     RVLVVDDDPTVAEVVAGYLDRAGYGVERAVDGPGALERFTANRPDLVVLDLMLPGMNGF
                     EVCRRMRAYGPVPVIMLTARGDEEDRVLGLETGADDYVTKPFSPRELVLRVASVLRRSR
                     SGAPEQGGGTLRTLTGAGLSLDPGARSATLDGGALALTLREFDLLSFFLRHPGRAFARE
                     ELMREVWGWDFGDLSTVTVHVRRLRGKIEADPANPRLIRTVWGVGYRCDLPDAGEPA"
ORIGIN
        1 ctccggagca gaagcgcttg cgacgccgcg cgtcggcaat cgtgagcagc gcgatcagca
       61 gtctgaacgc cttgcggcgt tcttcgacag gcgcgagacc agcgaccttt cccagttgct
      121 cgtcgatccg gcctcgtgag atcagcactg cgggcgtatg cgtcgggcgc agcccggcac
      181 ggcggatgct ttcaggtgcg tcctcggcaa gggcgcgtgc ctggacgcag tgatggcgca
      241 ggaacagcag cacctcggac tgttcttcct ggccgaggcc gtcgaaccat gtgatgccct
      301 ctgacatcgg gcgcagcccc tgcgcgagct cgttgagcag gacgtcgcgt tcgttcatga
      361 ctgcctcctg tgggacagac gccgctgcgc cgcggtgatc aggattccga gcagcaccgc
      421 cagatcggcc gcgccttcgg catcgtcggc ccagcgtgtg gtttgcagtg ggtgaacctg
      481 gtcgaggagg acgccttcgc gcgccaggac gaaggccaat gccagcatgg ccgcgcgcgc
      541 gttgccgtcc tcgaacggat ggaagaagag gacgtcgagg taggtccggg cagcgcggga
      601 ggggaggggc aggtccggtt gagcgctctc ggacagacag cgttcgaatc gcgcccgtgt
      661 gtcgggggcg aggccgtagc gctcccgccc gcccttcgcg aaggccggca tcgtgcggaa
      721 gccgacgagg ccgtggctca gcacggtccg ctgccatctc ttcatgaggg cgaaggtcag
      781 cggcctgccc tgctccgcgt cggcgaaggc caagtcgagg gcggtcagta cccgcgcggt
      841 tccctcgctg tcacggccgc ctcgcgctgc cgtgaagaag ttccggaagt cgtcgcggac
      901 cggtgctccg gagatggggc gtgtgccgcg ccaggatggc catgagatct ccgttcggat
      961 gagcatccag tcggcaaggc tgtccttcgg tcggccgggt ccggaggtca tctgattccg
     1021 ccggcgcctc tggcgaaccg cgagctcacc gcgtcgacca ccggaacgtc aggtgcgatc
     1081 caactgccga accggccgcc gaccgcgttc ctgacgatct ccacggcttg gccctcgtcg
     1141 atgccgttgt acgcgaggaa ccattgaagg acttgcatgc agtggccgta ccagccgctc
     1201 tcggcctggg tgcggtcagc caccacggtg accaggcgcg tgcacgcccg ctcccagtac
     1261 cagaggtccg tcgaagacac tggggtgttc tccggtgggg ccagggccgc gaaccgctcc
     1321 gccaggtctt ccagccagtc acgccattcc cgaagggcct caacaaccag cggggcagtc
     1381 gcccccgggg ttgtcacgga gtcggatgaa cagcaccaca cctcgacgat ccctccgtcg
     1441 acgtcgccct caccgaccga ccagttccat ccgcaagccc atcggccgta ccggcccgcc
     1501 aggaactcgg tggcaggatc caacgaacgt cggcgatcct cgcgagcgac ttcacaggag
     1561 ggcagcaagg gcacgacaag gcacgccaac tccttcgccg catcggcgtc catctcgaac
     1621 ggatggcaag ccggatccac gtctgcccac gtcagggtat gtgcccacag ttcactcacc
     1681 gtcccactct gccttgcgca gcggccctga ctccactccg tattgagcag ccgccccatc
     1741 agcgggaaac gatcttccac ttggtggcgg agcagtccga caactactgg tactcgaaca
     1801 accaccaagt cgttattgac gccgacaccc gcctggtcgt cgtggtcggc cagcccttga
     1861 ccggccaccg cgatgcccgc aaagcatggg aggaatccgg tgccaaagcg gccgccggca
     1921 gaacactcac gaccgccgac ggtggctatc ccggcaccgg gctcctcatg ccccacctcc
     1981 gacgcaaggg cgaagacctt ccggactgga gggaagcaca caacaagtcc cgcaagcagg
     2041 tccgagcccg cgtcgagctg agtgtcgtgg cctcgccggc ctgggcctgg ggccgtcgtc
     2101 gcctacgacg gccagggggg aaccggtctg ccgtgcgcgg ccagcgcctg gctgggagcc
     2161 ggaggtgtcg ccctgcgggc gtacgggccg gtcgagggca tcgccatctt ccacagcgcc
     2221 gcgcctgccg gcggtgggcg ggtggtcacc ggcagcggat gcgggagatc cgaccagtca
     2281 ctggcccgat gacgcgcgcc cgtgggcatg cttcagccgc atgcgcgccg ccgtcacctc
     2341 accggcgccc acgatcgccc agaacacatg gcgccaatat gcggcctacg taaaccagtt
     2401 gcggactgca aaggagtgtt gcgtagggtg gccgcacgat cattgcatct agggggcgat
     2461 caggatggtc gagcgttgcg atagccatgc tcaggcacgg ggtggacatc gcgctcgcgt
     2521 agctgccccg cgcacgcgct gagccacgag ccgccccggc tgcttttgcg cctcgggccc
     2581 gagagatccc cgcgcaccgc actgagcgtg atgatcctgc cgaacacgat ttcaaggaga
     2641 gctgatgaac atagcgcgcg ccctgaccgc taccgccgcg acggcggcgc tggtcgcggg
     2701 ggctacggtc ctcgccaccg gcaccgcgtc ggctgccagc tacaagtgca cgacttcgaa
     2761 gaagtcggtt gaccaccccg gcaacacggt caacgacaac ttcaacttct ccgtcaagac
     2821 ctgcgccaag cgtgaagggg gctacatcta caccaaggcg tacgtctcgg tcgatggccc
     2881 ctggggcttc gccggctcgt cctccgtcaa cgacgcacgc gcgctgatcc aggtcaagcg
     2941 gagcgtgtcc gggaccgacc ccgtgtccaa gtacgcatac ggaaatggtc tgggcagcaa
     3001 gctgaacaac ctcgacgcct acggcaacac gagctacacg agcccgaccg tgaagcacaa
     3061 ggccgccgcc ggtagccgat acctcggcga cagcgtcatg cagatcgact ggaggaacga
     3121 cggcaagggg cggatcagct acaacttctc cgcatcgccg actgtctgac gctcacgcgc
     3181 gcttggtgtc ccgctctgaa gaagtggggc accaagcgcc gggcccacac ggagagcgag
     3241 gtgctgcctt gactgcacgc ctccaacgcc tcactcctcc cacgcgccac gggccacttc
     3301 ggccatgacc tccgtagcga tgtcgaggag ggggcggaag ttcccgtggg cggcttccca
     3361 ccacgcccag gtaagcgggt cgaggatatg gcacgtgata agcgcgtccc agtcggccgc
     3421 cgcccgacac cgttgcgtgt ggtggtcctc gtgcgggaag tgccccgtgc ccggcgcact
     3481 ctcaacacgc tgtcccgtgg gacaacgtcg ctgctttcgt cgagcagacg caacgcgcgg
     3541 tccgtgtcgg tgaggttggt cgtgctgacc atgtcgatca ggctgaccat gccgtcatcg
     3601 ggcgtggatc ccggtttgta gccctgctcc tccatcagct cgggaaggcg tcttgcccga
     3661 cgcttgacgg agaggaatgc cccttccagg gccttcgccg gcctcgcgtc cgcagcgacg
     3721 gaggtggggc gtccggtcaa ggcgatgggc gccactgccc gggacgcggc gaaggccggc
     3781 gccccgcacg ccctggcggt cagggacacg atcgacgcgt tccgccagtc ctcaccgtcg
     3841 cccacgaaac ccgtcgcccg ccgcacagac accaccatca tcgccgcagt ccctgagcag
     3901 gtgcgtccgc tgctgacccg gctgtcgggc ttggggcatc tgcggactgg gagacagagg
     3961 tgcccctccc ggtctcaggg acgttcacca cccccgcccc gggagtctgc gtgcggacgc
     4021 ggtgctgacg gcgccggagg acggggtgcc ggtgatgtcc gtggaggtcg acaaccacac
     4081 cgaaccgccg ccgccgtcgc caggaagatc gagaactacc cgccgcttct gggcccgcct
     4141 ctcgatgatc ttcccgtcct tgagcgtgaa caggttgagc atgggaaaac gtacgtgcgc
     4201 tccgcgtggg ggatgccgta gtgctggtgc actcctcggt gtactctcag aatgcgaatg
     4261 tgaatttaca ttcgcatcaa attggaggtt cgaccatgac cgacgaccag actcttacgc
     4321 ccgtcaccgt gacgctcgag gccggcccca ccggcgccgg gagcatcgac gacctcgagc
     4381 tcttctacgc ccgccgtgcc ctaaaccgtt tccggacact gctgggccgc caggggctcc
     4441 tcgacctcct ggccgcggac atcgaggaag gcaacgcctt cctgcgtgaa agcgctcgga
     4501 cctccgacgg cagcttcaag gcaggcacca ccgtcctcgc cacgcgaggc ctcagctcgg
     4561 gcaccttcct cgcctggatg gacgaggcgt tcgcaggcga cgagagcgca ctcctcgcag
     4621 cacaccccga gcactacgtg atgggaaccg acgccatcgg agcgcgtgtg gtggagaaca
     4681 tcggtcccca cgtcgcctcc ttctacatgg gcggctgggg aacggacgcc ctgggttggg
     4741 ccgcggacgc cgacgaactg ctcccggagt cggaatttcc gcgcaagatg tcctccaacc
     4801 tcttcctggc cgacggcacc gtcgtcggac ggtcactgat ccagttcggc gacaccgccg
     4861 acggcttcac ggcccacctg acggtctact ttccggtcac gtgcccggac gaggtcctcg
     4921 accaccacct tcggcactac gccgtcgagt tcaggaactg gatcgaggcc gccgcggctg
     4981 cccgcgcctg aattgcccac cgtgcgcggg gccgccccgg cccgcccggt gggcaacgcc
     5041 gcgcctgttc ttcgactggc cggagctgga caccgtgctt gtacggaccc ggattcggca
     5101 ggggcggaca gggggtcgcg agggaagtgt ccacgctcgt cctttcgccc gtgctcagtg
     5161 cggtggaggg cgggacgggc gtgtggcgtg gcgtcggtca gcggcccggc ctcgccaggg
     5221 ctcacggcgc tcatcgcagg gccggcgaaa gtgacagccg ggcggcgatg cgtgaagcgc
     5281 gcggtatcgg aaaggcgccg tccgctccgc cgggacactc agcgggaagg atcatcgccg
     5341 ctggccgacg gtgatcctct tccgggtgcg gaccggtgtg cagtggcgga atccgctcga
     5401 atgattcggg ccgcgggatg agagccagcc ggggccttcg ggcgcacggg tgaggtgctg
     5461 tggcttccgg gagctggatg ggggtgctgt cagggcgggc ccggttcctc cggggccagc
     5521 gccaccagta gttgacggat ctcgatgagc aggccgccgc cgacggcggt cgccgaattg
     5581 tccgcctgac tgtgcagccg gccgagcagc tgctcgtagc gttcccaagc ggcgaccgcg
     5641 gtctctcgag gggtggttcc gtgctcctcg aaccgggcaa gggcctcggc ccggtccgag
     5701 cacaggcgtg cgaggtcacc ggccagagcc gcgtagtcac gggtgaagct ccccgtcggg
     5761 gcggagaggg cgtgggaccg ggccgcgatg ccggacatgg tccgggtgag cgccgtgagg
     5821 tggtgcacga cgttctccca ctggtggtcg gcctgaggcg gcggatgcgg cacgaagtga
     5881 gcgcggcgca ggcgtcgtgc cgggttcaga cgggtactct ccgcggaccg ccgccgcgca
     5941 accgccacgg cctccacgcc gcagcggagt ctgcgcgccc ggtcctccca cgcctcggct
     6001 tccgccgcgc cccatggctg cgtcaaaccg tcggcgatcg ctcgcaggag accggagcat
     6061 tcgagtgcca gggcgtggag gttggagcgt acgtcgtgga gacgtagggg cggcaggacg
     6121 aacgcgttga ccgagaggcc gatggctgct ccgatgaacg tctccaggag acggtggccg
     6181 atctctcccg gctggtagga accgtaggcg atgacgaaca gggcggtggt cgcaccgtag
     6241 atgccgtgcg ggccgagccg ctgataggcc gctatcagcg tcaggggagg taaggagatg
     6301 gccatggcgt gcaacgtgct gccatcggtg aggtacatcg ccacggaggc ccagaccgcg
     6361 cccagggaga tgatggccag ttgctgcaca ccggcgcgca gcgatctgta gacggtcgta
     6421 tcgaccagga tcagggcggt ccacggagcc atcagggcca tggggctctc gatccagaat
     6481 gctgccagtg cccaggccag catggccgcg ccggctgcct tgagagcctg tacggcagtg
     6541 gcgcgctcgg ggccggagtg ccgcagggcc ctgctcgcac tccgtctcac cgcgtcgagc
     6601 tcgtatcccg tgtgccgcca tacagtcatg acgagtgtgc gcaatgccga cccttcccgc
     6661 gtgtggcagc agtcgtgtcc atcggccagt cgcgcgcccg cgcacccgtt atgcgaacga
     6721 ggcaggacag gcgcgtggcc cggcgaacag ggcgccgggc cacgaactgg gttgacgcgg
     6781 gccgacaggg ggaggccggc cgggggcggg ccgccgctgc ccgtggtggc cgggtgccct
     6841 gaggcccgga gcgggttcag gctgccgcgg cgtatgccga ctcgagagcg acatcgacac
     6901 ggggatggac gacgagcctt gcacctcggg agtcggcatt gtcctccagt agccgccgca
     6961 cgggggcgtc gtgggtggcg accgagaaca gcacgttcag atcgctgcac tggcgatggg
     7021 cacgcaggac ggcgctggcg gtggcagggc tcgcggcacc gtcgttgatg acgacgagta
     7081 ccggtgacgg ctggtacgcc tgtgtgaagt ccatgatcct ggttgccagt tcggcacgtc
     7141 cgttgatccc cgggtcctcc cgcacggtga ggacgaggac atcgtgttca cgtctgtggg
     7201 acagcatcgc gacctccgct tccaggcccg gcaacgggct cgtgtgcact gcgtctgccc
     7261 ctcccgcctg ttcccatgca gggcattccg cccgctcggg tggcctcacg ggcgaggcgt
     7321 cggccgctgc gtcagacacc cggtcggcag gacgctccgt accaggtgag agcaggtctg
     7381 cgctacggcg ggacgatctc cgcggccgac tgacgggaca ccggctgacc ggcgcacccg
     7441 gcacaccgcc cgggcgcgcg ccgacgccgc tcgggcccgt cgagtccgga accccgggcc
     7501 tccaggctcc gggccgcggg tggcctcgcg tgcagttcct gccgggctag tgacctgagt
     7561 cggaggtttg tcgttggtcg ggtatggggc gtccggggtc atcgtcgaaa cccttgagca
     7621 aaggccgaaa aacgccaccc atcggtcgac cagatcgatg gcggccgcca cagggatgtc
     7681 acagtcggcg atctcccgaa tctggcgggc gttcggactc gcccccacac tgctcgcaga
     7741 cgttcaagcc agtgctgtgg ccgtgaacgt tcaccggggc aggggcaggg gcaggggcag
     7801 gggcaggggc gggcgctcgg cctggctatg ctgcatctcg ggagtagcgc tcggctgtga
     7861 ggggttgcgg aatgttggtc gaggtggccg gggtgcgcgt acccatagga cgagcggcgg
     7921 aggcggcgcg aacagtctgc gtggaatacg ctgatgacgc gctgtatcac cactctgtgc
     7981 ggtcctactt cttcggtgca gcctgggcgg aggctcgcgg cctcgacttc gaccgcgaac
     8041 tgttcttcgt tgcagcgatg ctgcacgacc tggctctcac cccgcctttt gacagtcaca
     8101 ctctcgcttt tgaagaagcc ggtgggcact tggcccgcgt tttcacagcc ggtcttggct
     8161 ggccggttga gcgacgcgac agagtggctg acctgatcgt gctccacatg cgagacgaca
     8221 tcgcgccgga agtggacgtg gagagccggc tgttgcaggt ggggaccagc gcagatgtgt
     8281 ctggaacggg actggaggcg ttcggcatct ccttcacgga cacccttgtc agtgcctacc
     8341 cccggctggg cttcgcccgt tcattcgtgc gtctgttcca ggaccaggcg gaacgcaaac
     8401 cgggctgtgc ggcctcggaa ctggcagcag gagagtgggc ggaacggact ctctcccatc
     8461 cgctcgatca gggttgaagc cggacaggtg tagggcgctg ccattcggct cggcgacgac
     8521 acggcctccc cagcggatgc cctttctcga ttcgaatgcg ggcgcactcc ttgcgttggg
     8581 ctgcgaggac gtcagcttgg caggcgttgg cgttgcaccc gcgcgtcctt ggcaagcaga
     8641 cgttccccgc gtggcacagc cccgctgagg cgttggggcg ttcccggggc gggctgacga
     8701 cgaaatcacc tggctaaccg tgcacaagct cgttagtgac ccgaggagac cgttgcgggc
     8761 ggcggcaccc atcggctggt gcggggcgcc gtgtcggtga tgccgaagtc cttcctgagt
     8821 tcctcgggga cggcgtagtg catgacccgc ccgcgggtga gggaggacag ctcgaagagg
     8881 gtggtcaggt ggccgatgcg gtccagtgcc cgggcggcga ggggtgatcg gtcctcgatg
     8941 gcctccatga caccgagaac atgcggcatg gctccgacga cggtgtccca cgtggtgcgc
     9001 ggcacctgga gccagtcggc acaggtgtcg ccgacgaggt agcggatgag cgcggagacg
     9061 accgggtcga agaaggttcc gggtacgacc tcttcgtaga ggtcgatgag ctggcgggtc
     9121 aggtgtgcgc cctcctcgga aggacccatg tgccggagca tgtacagatc gaggaactgc
     9181 ctggcttcgt cgagcgactt gggtacggcg tcctggtcga ccccgagcat cgcgccgacc
     9241 acacgccagg cgtagtagta cgcgtccgcg cccactgccg acatgtggat cccgagccgg
     9301 tgaaggctgt ccagcacgac cagggagaag aacatctggc cgccgatcag gtcctcctga
     9361 cagatgggcg tcccgagcgc tccggtgtcc caacggtcct cgcgccgcag gtgatggcgg
     9421 atggaggcgt ggaggaggcg caccttctgg gctgcgggga tgaagcggct gcccgtctcg
     9481 aaggcgtccg gctgcatcag gtagacggtg aactgccccg tctccgccat tcgcttggac
     9541 gggtaagaga gtccgtgggt ggccgacagc agcttcgcca catgggggac gacgtagcag
     9601 gcgggcatgg aggcgaagga cagggcggtg gagatgtgta cgttgttgtc gatgaagaac
     9661 agccgggcct tctccatctc ctcccagtcc acccaggccg gcggtgcact ggtggcagac
     9721 aggtactccc gggcgacatc gggcagtccg tcggggagcg gggcgccggc ggtggagacg
     9781 tagcgcatca gcgtgttgaa cttccccacc tcgccgcgct cgaagagtgc ggcgacagtg
     9841 gcgtccgcga gctcgtcccc ggaccggcgc agggcgtcca acgacgtttc ggtgtaggtc
     9901 atggcagtac tccttgggtt gctccgagtc gtccacacgc gggcggaggc agcggcagcc
     9961 gggggaggtc ccgtttccgc cgagctcccg cagcgcgtgg tcaggagagg cggacggtga
    10021 ccgaacgtgc cagagcggtc agggcgtgcg tggcgggtgc gggcacatcc accgcgtgca
    10081 gggcatcgag ggcctcatcg acccgtacgg tgatcatctc ctcgatacgg tcgggggcgt
    10141 ggagccggcg catcatctcg cgcaccgtgt gcaggccgtc ctcgcccacg tcgcggcggc
    10201 ccaggatcgt gcgcaactgc ctccgctcgc cctcaccggc aacacgccag gtttccgcca
    10261 gaagggccgt gggccggcgg ccgcgcagat cgtcggcgtt ggccttgccc gtggttccgg
    10321 ggcttccgaa caggccgagc agatcgtccc gcagctggaa cgcctcaccc aacggcaacc
    10381 cgtacgccgt atagccctcg cgcagccgct ccccggcccc ggccagggcg ccgccgatca
    10441 acaggggctg ctcgacggtg tacttggcgg tcttgtaccg gatcaccttc agggaatccg
    10501 taaggtccgg gtccgctccg gtgcgcagaa tctccaggca ctcacccgcg acgagttccc
    10561 gggtcagcac cgaccacagc gggcgggccc gggcgaggta ggccgccggc agaccgctgg
    10621 tggcgaacag ctgtccggcc agacccatca gcaggtcacc caccagcatt gccagcgacc
    10681 tggcggcgcc ggcggcacgc ggccggcggc gaagcgcact ccgcagggcc atgtgcgccg
    10741 tcggccggcc gtgccgcaac gggctgtcgt cgatgaggtc gtcgtgcacc accgccgcgg
    10801 cgtgcaccag ctccatcgac gccgccgccc gcaccaacgc gtcgttgtcc ggctggccca
    10861 ccgcgcgcca gccccagtaa cagaacgccg cccgcagccg cttcccgtcc gcgacggccg
    10921 cctccagctg ctcggccacc ggtcccaggg ccgcatcgat ctcggtgaac cggtcggcct
    10981 cctgggccac gaaccggtgc agtacgtcgt cgacgcgggc cttgaaggcg accggctccc
    11041 accggtcact cgccaccggc ggccttccgg gccagtgact cccgggcgag gacctccaga
    11101 tgggccgggg gagcggtggc gtagcggtcc aggaccaggc gtccgcgcgc cagcaggtcg
    11161 tgttcggccc cggctgccag ctccgcggtg tccgaacgcc ggagcaatcc gcgcatcgtc
    11221 cccagggccg aacccaccgt gctcaccgcc aggtccgcca gcccggccag caggagcacc
    11281 acctgcgcct ccgggccccc accgtctctc gcatcctgcg tcatgccgtc tccccacacc
    11341 cactgcacat ccgggcggcg ccggtcgagc gccgtccctc tcaggatcgc gccgcacctg
    11401 gatcgggagg ggagcaaatc accatcgagt gagtacctcg cccggccgta cggatggtgg
    11461 cgaacaccct cccgctgcgc tcaaacctca gcgccgacgt tgtccgctcc tcctgcgacg
    11521 gagcctcttc ggtccgggca cgggcttcgc ggagtcgtac gtgccgtctt ctccgcagaa
    11581 ccgggcgtga ccgtccaact cgtgaagtac cgtgcacggg aagttccctg acgcttcgtc
    11641 aggacgccga gcgcggagcg gtcggggtcc gccgttccat tacgtcaccc tgcccgacgg
    11701 tcaccagggc tggatcgacg tggctggagc gggccgacgg gcagctgacg ccggaccggc
    11761 tgcaggtcac cctcttgagg tggttcccca cgccgcccga cggatcctgg acagctgagg
    11821 accgcgccgc gacgggacat ccgccggggc gcggttccct ccgtgtgccg ggagaggatg
    11881 gcttccggac ggcctgtgcc cggtcgtcca gcgccttcgc ggcgtggccg cagcgcgggc
    11941 cggacacctg gacctggacc tacgtcacgt ggtgcgtatg cggcgagccg ctccgagcat
    12001 cgcgtccacc atgaggaagc cgatcagggt cacgcccagg acaggcagcg cccagcacag
    12061 ggcggccacg gccggaatgc ccaggacgag ggccgtgagg ggaagccggc gccacgcgcc
    12121 gcgctcgggt gccttgccgg cgagcgcggt gcgatcggtc cgtgtcgggc gacgctgcca
    12181 ccacatgcgg tagccccaga tgatcaccgc ggtcaggccg agcgcgatca ccgcgagcac
    12241 gatctggttc acgatcccga acagcacgcc catgtgaccc tgcacgccga gcttgctgag
    12301 cttggccagg accggatacc cggcccacct gttgtgggag acgacctcgc cggtcgtggt
    12361 gtccacggcg acctggtcgt agtgcaccgg ccagacgttg tcggtctgcg ccaccaccca
    12421 cgcgctcgcc ggatcggcgg ggggcgtcac ctccacggtg ccgtccagtc ccgcgccccg
    12481 cgccgctgtc agggccgcgg cgaaggccgc cggatcggcg tcgcccgcct cacccccgga
    12541 tccgccgtgc tcggcgtgct ccgcgtggtc gccggccggt gcgtccccac cggggagggc
    12601 ggtgtccagg gccggcgccc ggccgttcgt cgcgtccagg gcctgcccga accgctcacc
    12661 ggcgtgctgc gaccaggtga gtccggtggc gctcaggaac agcagaccga gagccagcca
    12721 cacccccgtg gccgcatgcc aactgcgcgt ccggcgcacc ccgcccgccg tgcggtccgg
    12781 gagcagcacg ccccgggccg acttcgctcg cctgcccctg ctgcgcccca gccacaggac
    12841 gagaccaccc gcgacgatca cccacagcca gctcgcggcg acctcggagt acaggcgtcc
    12901 ggtctccccg agatggagat tgcggtgcag gtcgtcgagc cacgtggtga gcggtgtcga
    12961 cccgaaccag gtggtcagct cgccctgtac ctcggcggta taggggtcga cgaacaccgt
    13021 gcgctgtttg tctcccagct cgggcaccga gagcaccaca cgggtggtgt cctccggccc
    13081 cggcggggtg gtgacggaca tcgtcgtgcc ctcggggtgc gccgaacgcg cggcggctat
    13141 ctgttccgcc agcgggcggg tctcgccccc gacgtgctcc acacgcaact ggtcgccgta
    13201 cacgagcgcg tcgagctgcg gcgcgagggt gtaggcgagc cctgtcaacg cggccaccag
    13261 caggaacggg gccaccagga caccggcgta gaagtggagc cggaccagaa ggtgccgcag
    13321 ccccgcccag gaccggaccg ggccgaggtg ctcggacacc ggcccggccg acgtggtccg
    13381 gtccggcgcg gcacccgtcg gatcgtggtc gttctgcggc agctcttcga ttctcggaga
    13441 catgcgtggt cctcatcggt aggcggcagg gcggacggcg tgggccggct cgggaggggc
    13501 ccgggccatg cccgacggcc ggtggggggt ggcgcggacc ggcctcggca gccgccgcgc
    13561 acaagcctcg tgaacggcgg atcgcatcgg ccccttcgtc cttccacggg gcagtagtcg
    13621 gtccggggcc ccggaaagtt cccggccgat cgactccgtt ccggcaggcg tcgaagaccg
    13681 ctcacgcaga cgtgcgacgg cagtctcccg tgccctcggg catcaggggg tgcgaaggcg
    13741 ggtggtgggc cggccaagga cttcccgcgc cctcaccgca gggggaacag ccgctccgtc
    13801 gtccacgggg tgaacggcag gacacggatc ggcgccaccg gccgccgggc gtccggcccc
    13861 tggtggagcc gtccgcgcag gcccggacct gtggccaggc cggccgtcgt ccgcccccgc
    13921 ggcctacggc gccgtgttca ttcgaggggc cggcccctgc gcccccctct caccatccgg
    13981 tccacagtag gtggttgatc agcagcgcca ggatcgcctg cgcggccagc cagccccggt
    14041 gatcgcgccg ggggagcagt gcggtggcgg ggagcagcca caggaggaac ggttgccaga
    14101 tgcgttccgt ctcggccttg ctcatcccgg agaggtccgc tgcggcgatg gccagcagcg
    14161 ccgccagcac cagcagggcc aggcacgttc cgccggtcac cgcgccaccg ccgcgggcgg
    14221 gaagcaggct gcgtacgcct ccgggggccg ccacgaccgc tcgccgcagc ccggcgacgg
    14281 tggcgaggcc tgctgccagg gtggcgcagg cgaggttgcc ccagacccag taggagtacg
    14341 gccggacgcc gcccgcaccc tggtagtagc gctcgaccag caggtggtag gcctcccacc
    14401 agctgaatcc ggccacggtg aaggcgacgg gggcgaccag cgccccggcg aggaagggca
    14461 ggaccggccg cgcggtccgg gcgagcagga ggacggcgca caggagtacg ccgatgagcg
    14521 tcaggccgta actcaggtag caggtcagcc cgaacagcac accggatccc ggggcggcgt
    14581 accgggcgag gcgcgtcctt gcggtcgcgg cgagggcgag cagggcgatc gaccaggccg
    14641 ccaccccggc gaagtagccg tcggccgagg tgccggtcca gacggcgaag ggagcgagca
    14701 ccaggaaggg ggcggcgccg cgtgcgaggc gctcaccggc cagggcgcgt acggcgatca
    14761 ggacggccat cacacccgac gcgccgagca cgatgcacca gaccccggcc caggcgccgc
    14821 cgccgagacc gatgcggtcc aggccgacga aggtcagcgt ggcgcccggc gggtgaccgg
    14881 cgacatgggc gggccagttc cccggcgggc cgatcacgat gtggtcggtg aacccgcgca
    14941 gggccgacgg gacgtcctcg aagcggtcga tgacccgcag gtactcgtgc ttggtggtga
    15001 gccggcgggc gacaccccgg tcccagccct cgatcagcgc cagcgagagg atccaggcca
    15061 gggacgccgc ccacgcggcc accagcaggc gccgccacgg cagccgttcc gcgaggccgg
    15121 gcccgtacgc gacgacggcg gccgcgacgg ccaccgcggc cggggtgccg gggcccacgt
    15181 gcgggtccca ggtggcgagc agcggcggcc agtggacctg cagactgccg ttcgcgttct
    15241 gcaccgccca ccccacggcg gacgccgccg ccaccagcag caggcccacc gcggcggcgg
    15301 ccaggtccgg gcggcggtcc ctccgcccgg cgggaggtgc gaactcctcg gcggggcggg
    15361 tgctgtcgct gcgctcctcg gtcttcacag gggcacgcta tgcacgccgg tgccccgggc
    15421 cgcggtgcga cgccgcggcg tcacacaact gtcagatcct ccgggtgacg tcagacttcc
    15481 gtcaggagtc gtacaccccg cggggccatg ggcccggcat agcgtcggcc catggacgac
    15541 tcacgtctca agacccgagc gcgcctcgcc gcgccgcagc tcccctccac gcccgcgttc
    15601 tggcgcagcc ccgtccgggg agtcaggttc accgcggtgc tcggagtggt cctcctcgcc
    15661 gggatcaccc tgctgttcgt gaccggcctg ctgtcgtacg cggcgtacaa cccggacctg
    15721 gcggcggtga acgacaagac gccggacaag gggctgctgg gcttctacct cttcgcctgg
    15781 ccgaccggcc ctcactggct gtaccgcctg acgcaggggc tgcacgtgac cgtgggcatc
    15841 gtcctcgtcc ccgtcctgct ggccaagctc tggtcggtgg tcccgaagct cttcgtgatg
    15901 cccccggccc ggtccgtggc gcaggcgctg gagcgcgtgt ccctgttgct gctcgtgggc
    15961 ggcgtccttt tcgagttcgt caccgggctg ctgaacatcc agctcgaata cctgttcccc
    16021 gggtccttct atccgctgca cttctacggg gcctgggtgt tcgtcgccgg gttcgtggcg
    16081 cacgtgggcc tcaagctccc ccggaccctg cgcgtcctcc ggcacggcat tccccccgcc
    16141 gcggacgaac tcgccacccc cgaccccgca cccccgaccc tctcgcggcg cggcgcgctc
    16201 accgtcgtcg gagccgggtc cctgctcctg ctggtcacct cggcgggccg cagcttcgac
    16261 gggccgctgc gccgcgtcgc gctcctcacc ccgcgcggcg gcgccgagcc gggagaaggg
    16321 cccaacggct tccagatcaa caagacggcc gccaaggcgg gcatcgtccc ggcggacacc
    16381 cgggagcggt ggcggctcac cctggccggg cccgcgggag aggtccggct cacccgggca
    16441 cagcttctgg ccatgcccca gcacagtgcg gcgctgccca tcgcctgtgt cgagggatgg
    16501 tcgacctccg accagtggtg gcggggggtg cgcctgcgcg acctcgccgc gctcgccgga
    16561 cacgcggacg ggagggcgcc ggacgtcctg gtcgagtcgc tccagcccag cggccccttc
    16621 cgtaccgtcg cgctccgggg caaccaggtg gcggacccgc gctcactgct cgcgttcggc
    16681 gtcaacggcg aggagctgtc cctggaccac ggctacccgg cacggatcgt cgtaccggcg
    16741 gcccctgggg tgatgaacac caaatgggtg gcccggatga ccttcggagg agtgcgatga
    16801 ggaggctgcg ccgctggtac ggggcagggc cgctgcacct ggtcctcatg gccgcctcct
    16861 tcgccatcgc cgcgtacgcg gggatccggc tgctggaggg cggcgacacc tacctcgtcg
    16921 tgctgtggtt cgtgggtgcc gcgctgctgc acgacctggt cctgctgccg ctgtacacgc
    16981 tcgccgaccg ggccgtgacc ggggcactgg ggcgacggag gggactggtc aacttcgtac
    17041 gggtccccgc gctcctgtcc gggctgctcc tgctgatgtg gtggccgctg atcacacgcc
    17101 actcgcaccg ctacgaaccg gccgccggga tgtcccccga caggttcctc gggaactggc
    17161 tcctgatcac cgcggcactg ttcacactgt cggcgctctg gctggtggtg cgcaccgtgc
    17221 ggtcgaggcg cagggtgacg aagggacgcc cgtcggcctc ccactgatcg gtgggccgcc
    17281 agccgcacag tcgtgcgtac cgcagcagag cgggtctgcc caggcgcgcc caagggaagg
    17341 gagggccggg gacggccggt tcgcgcccgt cgtccagtcg gacctgtacg cgctcgtcca
    17401 cgtcctccgg cgccgtctcc gcgaggagga ggccgcccgg ggcgagcagc gcggcggtcc
    17461 ggcggagcag ggcgccgggg tcgcccccga tcccgaggtt gccgtcgagg agcagggccg
    17521 tgccccaccg gccctcgtcg ggcagctggt cgaagacgct gcggcgcagc gccgaaccgc
    17581 cgaggcgccg cgtgtgggcc accgccgcct cgctgacgtc gattcccagg gcgcggtgcc
    17641 cgtgtgcggc gagcgccgcc accagccggc cgggcccgca gccgatgtcc acgaccggcc
    17701 cctcgcagcg gcggagtgcg gagaggtccg ccgcgtcggc gtccgcacac cagcgttcga
    17761 cgtccagcgg cagcagccag ccgtccgcgc ggcgcaggaa gagcgggccc cggccggtac
    17821 gaagggcgtt ggcgtacgga tcggcggccc aggcggtggg gagcggcggg ccggtgggcg
    17881 gcagggtggt gctcatccga cggccgtccg ggtcagccgg gccagggtcg ccgcgaactc
    17941 cccgtgcggc gcggcctgcg cgacgtgcca cgcgtcgtcg gcctcgtcca cgtcccgcag
    18001 ttccggcaga tcgcccaccg tgagacctgc gtctgtcagg cgggcccgct ggacaccgcc
    18061 ggtgtgcggc agcgacatcg ggatccccag gaccagctcc ggccgcggtt cggccaggcc
    18121 caaggcccag aagccaccgt cctccgccgg tccgaaccag gcgtcgcact cgtcccagcc
    18181 gcccggcgac aacgcggggg cgaggtgcgc tgcggtcagc tggggtgtgt ccatgccgat
    18241 caggagcgcc gggccggtgc actccgcgaa cgcgccggcg atgcgctcgt cgaggccgcc
    18301 cgcgcactgc ggccgcacct cgatgccggg cggcagccag gggcccggcc gtccgtcgag
    18361 gacaaggatc cggcgacggg ccggcagcgt gcgcacctgg cgcagggtgt ccgcgaggga
    18421 ggcggcggcg agctccgcgg cctcgtccgg cgtgaacggc ggagtgagcc tggtcttgac
    18481 cctgccgggg accggttcct tggcgaggac gagcagcgtc gtcggccccg gcgtcaccgg
    18541 caggtccccg cgcccacgct gcccgtcccg gtcggcacgc cgggcggccg ccgcagcacg
    18601 gcccgcatgt cgcggacggc gtgccaggtg ccccgccagg tgccggtgac cttggacctg
    18661 ccggtacggg cgagataggg cacatccgtc tccgtgaccc tgagcccggc gtccgacgcc
    18721 cggaccacca tctccagcgg atagccgcta cggcggtcgg tgaggtccag ggccagcaga
    18781 gcctcccggc gggccgcccg catcggcccc agatcgcgca gccgcaggcc tgtccgggta
    18841 cggagcatcc tggagagggc gaagttgccg gcgcgtgcgt gcgcgggcca cgcgccgaag
    18901 cgctccggac atcgccgtcc gagcacgaga tcgctctcgc ccgcggccac ccgggcgacg
    18961 aggccgggaa gcagcgccgg atcgagggaa ccgtcgcagt cgcagaagca cacgtacggg
    19021 gcggtggcgg cgagcagccc ggcgtggcag gcggccccga agccgcgccg ggcctcatgc
    19081 acgaccgtcg cgccccacgc ccgcgcgatg tccgcggacc cgtcggtgga tccgttgtcg
    19141 acgacgacgg cgcgccagcc gtccggaatc cgccccagca cccagggcag ggccgctgcc
    19201 tcgtcgaggc agggcagcac gatgtccgcg gtgacagggg cggtgagttc tgccgaagag
    19261 tcgttcacgc cgatcaccct acggagcaga aaccggcatt tcgggctaca ggttcttacg
    19321 aaacgtggac atcgaccgtg tggcggcgca cggccgtccg aggcacggtg cagggatgcc
    19381 aaggttgcgg catgcagaac agcccgttcg aacccgcccc cggcccggct gcccacgccc
    19441 tctccggacc cgcccccggg gcgtgtcccg acggccccgc ccgggtgccg gagccggacc
    19501 cggcccgggg atccggcccg cgcgggcggg tactggtcgt cgacgacgat ccgacggtcg
    19561 ccgaagtcgt cgccggatac ctggacaggg ccggctacgg cgtggaacgt gccgttgacg
    19621 gtcccggggc cctggagcgc ttcaccgcga accggcccga cctggtggtc ctcgacctga
    19681 tgctgccggg catgaacgga ttcgaggtgt gccgccggat gcgcgcgtac ggaccggtgc
    19741 cggtcatcat gctgaccgca cggggagacg aggaggaccg cgtactcggc ctggagaccg
    19801 gtgcggacga ctacgtcacc aagcccttca gcccgcgcga gctcgtcctg cgcgtcgcct
    19861 cggtcctgcg gcgctccagg tccggagcgc cggaacaggg aggcgggacc ctgaggacac
    19921 tcaccggagc cgggctctcc ctcgaccccg gtgcccgcag cgccacgctc gacggaggcg
    19981 cactcgccct caccctccgt gagttcgacc tcctctcctt cttcctgcgc caccccggcc
    20041 gggcgttcgc cagggaggag ctcatgcgcg aggtgtgggg ctgggacttc ggagacctgt
    20101 cgacggtgac cgtccacgtc cggcggctgc gcggcaagat cgaggcggac ccggcgaacc
    20161 cccggctgat ccggacggtg tggggggtcg gctaccggtg cgacctgccg gacgccgggg
    20221 agccggcatg accgacacgc tgctcatcgc actgttcgcg ttcctgggcg ccggcgtcgc
    20281 cggtctgctg ggcgccctcg cgctgcggct cctgcgccac cgttccctcg ccgtctccct
    20341 ggccgtggtg gccgcggtcg cggtcgtcgc catgctcgcg ggcaccctcg ccgtcgcctg
    20401 ggcgatgttc ctgtcacccc acgacctcga ggtcgtcacg accgtcgtgg ccatggccgc
    20461 cgtggtgtcc ctgggcaccg cgatcctgct gggccgctgg gtggcggcca ggagccggga
    20521 cctggcactg gccacccgta cgttcggaga aggaggcacg ttcgccgtcc cgcaggagcg
    20581 gaccaccgcc gaattcgccg cgctcagccg tgagctcgcc gccaccagtg ccaggctcga
    20641 cgcgtcgcgg gagcgcgaac gcgccctgga ggcgtcccgt cgtgaactgg tcgcctggat
    20701 ctcgcacgac ctgcggacac cactggccgg actgcgcgcg atgtcggagg cgctggagga
    20761 cggcatggcc gcagactccg gccgctacct gcgccagatc cgtaccgagg tggagcgcat
    20821 gaacggcatg gtgggcgacc tgttcgagct ctcccgcatc cacgccgggt cgctcaccct
    20881 gagcccggcc cgtgtctccg tccacgacct cgtcgccgac gccctcgcgg gagcggaccc
    20941 actcgcccgc gagcacgggg tgcggctgat cgggcaccgc gtcgactcga tgcccgtcga
    21001 ggtcgacagc aaggagatga gccgggtcct gggcaacctc ctgatcaacg cgatcc
//
