LOCUS       NZ_LMEU01000029        10849 bp    DNA     linear   CON 26-MAY-2024
DEFINITION  Streptomyces sp. Root1319 contig_8, whole genome shotgun sequence.
ACCESSION   NZ_LMEU01000029
VERSION     NZ_LMEU01000029.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root1319
  ORGANISM  Streptomyces sp. Root1319
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 677541)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 677541)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140604
            Assembly Name                     :: Root1319
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001426615.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 02:19:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,915
            CDSs (total)                      :: 5,857
            Genes (coding)                    :: 5,667
            CDSs (with protein)               :: 5,667
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 190
            CDSs (without protein)            :: 190
            Pseudo Genes (ambiguous residues) :: 0 of 190
            Pseudo Genes (frameshifted)       :: 64 of 190
            Pseudo Genes (incomplete)         :: 160 of 190
            Pseudo Genes (internal stop)      :: 8 of 190
            Pseudo Genes (multiple problems)  :: 38 of 190
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:44:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 260272
            Orig. end                         :: 271121
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMEU01000029.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10849
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="butyrolactone"
                     /region_number="1"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..10849
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10849
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:5849](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5849
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="1"
     misc_feature    complement(239..252)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.51"
                     /tool="antismash"
     gene            complement(264..1022)
                     /locus_tag="ASD26_RS26700"
                     /old_locus_tag="ASD26_16070"
     CDS             complement(264..1022)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047017.1"
                     /locus_tag="ASD26_RS26700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_16070"
                     /product="HAD-IA family hydrolase"
                     /protein_id="WP_056793273.1"
                     /sec_met_domain="HAD_2 (E-value: 2.9e-12, bitscore: 42.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAALSPAAGLRSVRAVVFDTDGVITDSAPVHAAAWKRAFDACLSA
                     HGGQRPFDEGDDYRRHVDGRSRKDGAAAFLKSRGLDLPEGSPDDPPGTETVWAVAARKD
                     EVFTESLRAAPVAVWPGTVRLLHVLREERVPCAAASASRHATELLSGAGLLDLFETVVD
                     GNEARRLELPGKPDPALFVEAARRLGTPAEDTAVVEDALAGVEAGRRGGFGLVVGVDRT
                     HTPAGAADLRHHGADVVVSDPGDLLTGGDD"
     gene            1156..1359
                     /locus_tag="ASD26_RS26705"
                     /old_locus_tag="ASD26_16075"
     CDS             1156..1359
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006126199.1"
                     /locus_tag="ASD26_RS26705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_16075"
                     /product="hypothetical protein"
                     /protein_id="WP_056793593.1"
                     /transl_table=11
                     /translation="MVSTKRQTHRQAEYACPACKHTVASVLARHKTLGIFVPLWGPGPC
                     RNPACGRYVPTDEPEPTEHAGH"
     gene            complement(2375..3136)
                     /locus_tag="ASD26_RS26710"
                     /old_locus_tag="ASD26_16080"
     CDS             complement(2375..3136)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047018.1"
                     /locus_tag="ASD26_RS26710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_16080"
                     /product="transglycosylase family protein"
                     /protein_id="WP_056793272.1"
                     /transl_table=11
                     /translation="MPASPLAKRPVESALVLLLVLLSVLGLSGRSAASVPARAATTQAA
                     SVQVFPARAATAPTVMAPTVTAGTDWDRIAACESNGRWNINTGNGYHGGLQFAPSTWQA
                     YGGGQYAPRADLATRSQQIAVGERVARSQGLSAWPTCGRLGANGTSGPQAGSTPQRSET
                     PKAAPQRRSDSGPSSSQGSSHEASDAAGATDSHELAGTGTYVVQPGDCLSVIADRADVP
                     GGTDALFELNRELLDEGPDLIYPGQRLRLTA"
     gene            complement(3346..4080)
                     /locus_tag="ASD26_RS26715"
                     /old_locus_tag="ASD26_16085"
     CDS             complement(3346..4080)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155348.1"
                     /locus_tag="ASD26_RS26715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_16085"
                     /product="peptidoglycan recognition protein"
                     /protein_id="WP_056793271.1"
                     /transl_table=11
                     /translation="MWLRRTALGAMVVPLAVLVFRDAPVRLVAPEPVLARPVAPSEALR
                     PAIVSRADWHADETLVKEHATYTGAVNAVFVHHTNHANDYDCADAPTMLREMERDHVSG
                     EGWDDIGYNFVVDRCGTIYEGRAGGVGRSVRGAHAKGFNAHSVGVAALGSFGPGVPVPK
                     ALIEGIAKVGAWKLRPGTDPRSTVRMVSTNDESLYQRGEVVHLHAVSGHRDTFQTSCPG
                     DALYDQLPAVRAEMAKLRAPHS"
     gene            complement(4183..4830)
                     /locus_tag="ASD26_RS26720"
                     /old_locus_tag="ASD26_16090"
     CDS             complement(4183..4830)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047020.1"
                     /locus_tag="ASD26_RS26720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_16090"
                     /product="ScbR family autoregulator-binding transcription
                     factor"
                     /protein_id="WP_056793270.1"
                     /transl_table=11
                     /translation="MARQQRAIRTRRIFLEAAAEVFDEHGYDAATIAAILERAGLTRGA
                     LYFHFTSKEELARGVLEEAVTSDGVTPQTFKLQEWVDIALLLAYRLPREPMLSASIRLS
                     VDPRARSLFGTRWPDWITLGAELLTEAKERGELLPHVDPVATSRLLVGAWTGVQLVTES
                     MADAPDLVTEISALFELILPNNAVPGVLARLDTSPHRAERIIEENRAAAAAS"
     misc_feature    4858..4871
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.68"
                     /tool="antismash"
     misc_feature    4859..4872
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.99"
                     /tool="antismash"
     misc_feature    4859..4873
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.68"
                     /tool="antismash"
     misc_feature    4860..4873
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.77"
                     /tool="antismash"
     misc_feature    complement(4864..4873)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     gene            5001..5849
                     /locus_tag="ASD26_RS26725"
                     /old_locus_tag="ASD26_16095"
     CDS             5001..5849
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047021.1"
                     /locus_tag="ASD26_RS26725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_16095"
                     /product="ScbA/BarX family gamma-butyrolactone biosynthesis
                     protein"
                     /protein_id="WP_242413214.1"
                     /sec_met_domain="AfsA (E-value: 4e-16, bitscore: 54.1,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYVHLRRAEAVLVTGWRRLEDGEFSLTLNWPAPDGGLPYDPRML
                     TQAIRQSGLLIAHAEYGVPLSHHTLLHSFDFTVAPGFRVRSTGPSPLTVGISLAEPKKR
                     GRAVSSLGMDIRLYQDDSLVARADCDFGWISPGAYRRLRGEHLGAGWNTWELPAPADPR
                     TVRRATGTDVVLAPGGRPHHWRLRNDVDNVLLYDHPVDHVPGLVLIEAAHQAANAVLHP
                     ATFEATTVDTSFERYVELDRPCWIEAERAPASGPGGATVLVTGTQDGDTVFRGRLSGPC
                     G"
     gene            complement(5887..6651)
                     /locus_tag="ASD26_RS26730"
                     /old_locus_tag="ASD26_16100"
     CDS             complement(5887..6651)
                     /EC_number="1.1.1.47"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-171). E-value: 1.4e-14. Score:
                     46.3. Matches aSDomain:
                     nrpspksdomains_ASD26_RS26730_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155345.1"
                     /locus_tag="ASD26_RS26730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_16100"
                     /product="glucose 1-dehydrogenase"
                     /protein_id="WP_056793591.1"
                     /sec_met_domain="adh_short (E-value: 1.3e-34, bitscore:
                     114.9, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 4e-34, bitscore:
                     113.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDLLNGRVVLVTGASSGIGAAAARVFSQEGATVVLAARREDRLA
                     ALVAELRDKGAEASHVVCDVTVAEDAARAVDFAVNTYGRLDSAFNNAGLGGDRTPLHLM
                     GDDVYDAVMDVNVRGVWNCLRYEIAAMLSNDGGCSIVNTTSVGGLVAIPAAAPYIAAKH
                     AVVGLTRAAADEYAQQGIRVNAVAPGTTRSEITADWFGRNPGLEEMVNSMTPQGRTAEP
                     EEVANAAAWLLSDRCPFLTGTVLPVDGGFVNQ"
     aSDomain        complement(6139..6627)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD26_RS26730_PKS_KR.1"
                     /evalue="1.40E-14"
                     /label="ASD26_RS26730_PKS_KR.1"
                     /locus_tag="ASD26_RS26730"
                     /protein_end="171"
                     /protein_start="8"
                     /score="46.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLVTGASSGIGAAAARVFSQEGATVVLAARREDRLAALVAELRD
                     KGAEASHVVCDVTVAEDAARAVDFAVNTYGRLDSAFNNAGLGGDRTPLHLMGDDVYDAV
                     MDVNVRGVWNCLRYEIAAMLSNDGGCSIVNTTSVGGLVAIPAAAPYIAAKHAVVGLTRA
                     "
     CDS_motif       complement(6532..6627)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD26_RS26730_0001"
                     /evalue="8.20E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ASD26_RS26730"
                     /protein_end="40"
                     /protein_start="8"
                     /score="12.1"
                     /tool="antismash"
                     /translation="VVLVTGASSGIGAAAARVFSQEGATVVLAARR"
     misc_feature    6662..6677
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.18"
                     /tool="antismash"
     misc_feature    7222..7231
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.0"
                     /tool="antismash"
     gene            7313..8221
                     /locus_tag="ASD26_RS26735"
                     /old_locus_tag="ASD26_16105"
     CDS             7313..8221
                     /NRPS_PKS="Domain: PKS_ER (19-300). E-value: 8.4e-40.
                     Score: 128.7. Matches aSDomain:
                     nrpspksdomains_ASD26_RS26735_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155344.1"
                     /locus_tag="ASD26_RS26735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_16105"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_056793590.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 1.5e-18, bitscore:
                     62.3, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIAIQFDHFGGPEVLQPVELAAPVPGPGEVLLTVEAAGVNFADTH
                     QTDGSYLGADALPYVPGSEVVARTPDGRRVLARVSHGYAEQVTAKESALLEIPEDLGAA
                     EALALMVQGLTAWHLLRTSARLRAGETVVVHSAAGGVGSLAVQLAREFGAGRVLAQVSS
                     PDKERLVLDLGADAVVSYPLQEKADVVLDAVGGELFDLALDSLASFGRLVSYGSAARTG
                     FTPVDPARLGRLNAAVVGFWLRPTLAAPGAVDGPLEELFGLVADGRLKPVAGGSYPLTE
                     ARRAHEDMLARRTVGKVVLVP"
     aSDomain        7370..8212
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD26_RS26735_PKS_ER.1"
                     /evalue="8.40E-40"
                     /label="ASD26_RS26735_PKS_ER.1"
                     /locus_tag="ASD26_RS26735"
                     /protein_end="300"
                     /protein_start="19"
                     /score="128.7"
                     /tool="antismash"
                     /translation="LAAPVPGPGEVLLTVEAAGVNFADTHQTDGSYLGADALPYVPGSE
                     VVARTPDGRRVLARVSHGYAEQVTAKESALLEIPEDLGAAEALALMVQGLTAWHLLRTS
                     ARLRAGETVVVHSAAGGVGSLAVQLAREFGAGRVLAQVSSPDKERLVLDLGADAVVSYP
                     LQEKADVVLDAVGGELFDLALDSLASFGRLVSYGSAARTGFTPVDPARLGRLNAAVVGF
                     WLRPTLAAPGAVDGPLEELFGLVADGRLKPVAGGSYPLTEARRAHEDMLARRTVGKVVL
                     "
     CDS_motif       7697..7759
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD26_RS26735_0001"
                     /evalue="1.80E-07"
                     /label="PKSI-ER_m5"
                     /locus_tag="ASD26_RS26735"
                     /protein_end="149"
                     /protein_start="128"
                     /score="23.6"
                     /tool="antismash"
                     /translation="GETVVVHSAAGGVGSLAVQLA"
     gene            8311..9387
                     /locus_tag="ASD26_RS26740"
                     /old_locus_tag="ASD26_16110"
     CDS             8311..9387
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010063091.1"
                     /locus_tag="ASD26_RS26740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_16110"
                     /product="acyltransferase family protein"
                     /protein_id="WP_056793269.1"
                     /transl_table=11
                     /translation="MPSLTSRTPGPAPSGAGATDAAPARPGRDPYFDNAKYLAIVLVAM
                     GHSWEPLPDSGRVIETFYTFVYAFHMPVFIMIAGYFSRGFDLRRERVWKLVTSLIVPYA
                     VFEVAYTLFERLTGAPGFPLSPLTPYWLLWFLPALFLWRLTTPVWQTVRWPVAVSLVIA
                     AMGAVSSNIGGDLQLQRVLQFLPFYVLGLQLRPAHFDFVRRRAVRLASVPVCVIALAAA
                     YWAVPRTTTSWFFRRYGAEQLGSPAWTGAVVTLLLFGCAVVLSACFLAWVPSRSMWMTA
                     LGAGTLYGYLLHGFVVKGAIRLDLFEADLVATPLGRILVTVVAAAVVTLLCSPPARRVF
                     RFVVEPRLDWARKPAPAS"
     gene            complement(9413..9613)
                     /locus_tag="ASD26_RS26745"
                     /old_locus_tag="ASD26_16115"
     CDS             complement(9413..9613)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155342.1"
                     /locus_tag="ASD26_RS26745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_16115"
                     /product="hypothetical protein"
                     /protein_id="WP_056793589.1"
                     /transl_table=11
                     /translation="MKSRLTVLGVAVLASVFPAGTVHADETHTDSHNAPQVALIATGQV
                     DDPLEDVLEHATVLGGTQVTG"
     gene            complement(9834..10154)
                     /locus_tag="ASD26_RS26750"
                     /old_locus_tag="ASD26_16120"
     CDS             complement(9834..10154)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018960830.1"
                     /locus_tag="ASD26_RS26750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_16120"
                     /product="SCO5918 family protein"
                     /protein_id="WP_056793268.1"
                     /transl_table=11
                     /translation="MRCVIARFPFDLFKNEVEDSMKGIKPEPVTGDAVVISRRVYPVKQ
                     VGEIITRQDRRDFSAAEVTRALTRLGFTCRPAEVPAPAVPLTPLENASAMLGTPDDIRP
                     SV"
     misc_feature    complement(10173..10188)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.48"
                     /tool="antismash"
     misc_feature    complement(10598..10612)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.73"
                     /tool="antismash"
ORIGIN
        1 cgggtggatg cggtagcgca gcggcagcca gtcggggagg ttgaccatgt cctcgttctc
       61 gacctgctgg tcctggaccg aggaggtcag ccggttgtag cagcccgcca cataggtgcc
      121 cgggtagtgc ggtccgcccg ccggtgtctc ggacgcggcc cctctggtgg cgaagtagcc
      181 gttgcccagg gtgcacagcg cctcgcgcag gcgctccttc gccgggtcgt acccctcgta
      241 ggaccaggtc caggccctcg ccatcagtcg tccccgccgg tcagcagatc ccccggatcg
      301 gacaccacga cgtcggcacc atggtggcga aggtcggcgg caccggccgg ggtgtgcgtg
      361 cggtcgacgc cgacgaccag cccgaacccg ccgcggcggc ccgcctccac tccggccagc
      421 gcgtcctcca cgacggcggt gtcctcggcg ggggtgccca gccgtcgggc cgcctccacg
      481 aacagggcgg gatccggttt gcccggcagt tccagccggc gcgcctcgtt gccgtcgacc
      541 acggtctcga agaggtccag gagaccggcc ccggagagca gttccgtcgc gtgccgggag
      601 gcggaggcgg cggcgcacgg caccctctcc tcgcgcagca cgtgcaggag gcggaccgtg
      661 cccggccaga cggcgaccgg ggcggcgcgc aggctttccg tgaacacctc gtccttgcgg
      721 gcggcgaccg cccacaccgt ctccgtgccc ggcgggtcgt cgggactgcc ttcggggagg
      781 tccagcccgc gcgacttcag gaaggcggcc gcgccgtcct tcctcgaccg gccgtcgacg
      841 tggcggcggt agtcgtcccc ctcgtcgaag ggacgttggc ccccatgggc cgacaggcag
      901 gcgtcgaacg ccctcttcca cgccgcggcg tgcaccggcg cggagtcggt gatcaccccg
      961 tccgtgtcga agaccacggc acgcacggag cgcaggcccg cggccgggga gagtgctgcc
     1021 atgaccgggt ggtcccttcc tcgggtgggt cccccgttcc atggcaccag gttccggcgg
     1081 cgagcgcctt tcctggagcc tcaccaaaga aaactaaatg tctcgttctg cacacgtttg
     1141 ggctaccgtg agtacatggt cagtaccaag cgccagacgc atcggcaggc ggagtacgcg
     1201 tgtcccgcct gcaagcacac cgtcgcgtcc gtgttggcac ggcacaagac cctcggcatc
     1261 ttcgtacccc tctggggccc cggcccgtgc cggaaccccg cctgcggcag gtacgtgccg
     1321 acggacgagc ccgagccgac ggaacacgcg ggacactgag ccccggacac cgggcgccgg
     1381 gcacggtcag tgcccgccgg agcagggcag gggcacggcg cacggccggg gcgccgcgcg
     1441 caggacccgt cgaggccctt gccacgtccc tgcgcctgcc gtcctcgcac gcgcggcgtt
     1501 gatccggctg ccggagtgcc ctatgtcccg gccgtggggg atcgccgtcg cggtgcccct
     1561 ctccccgcgt cccgctcaca ccgacggaat cggctcctcc cccacctccg gactcggacc
     1621 gctccgcttc actcgcgcca tcgagccgtc agcccttcca tcgatcggcc cctccatcga
     1681 tcagcacgac cggacccgcc gtggcgcggt ctgtcgtcgt cactgtcaca cgggaacgtg
     1741 acccggcacg ggcgccggga tcccgaggac ttccccttcg tcgggcgcgg tagccgactc
     1801 cggctcggtc ggtcgggcgc gggatcgacg ccccgggatt cctcctcgtc ccgtcccggc
     1861 ggggtgcgcc gcttgtccgc ccaccccgga ggtgggccac cttccggtcc acttcggggc
     1921 caccccggca ggggcgtggc cacggtcgtc cggctcggcg ccggactgct gcacgtgctg
     1981 tggtgcctgc tgcccggggt gcagctcgtc ggggtgacgc gcgcggccct gcgggccggc
     2041 cacaccgagc ggcgcaccga gggagtcttc cgaaagtgct gccatgccgt gctgttcatg
     2101 gacggggcct acagccacgc tcccggggaa gcggcctcgg gtcactgcgg gaaagccgtt
     2161 cggattctgc tcgggccgag gggggaccgg cgcgacgagg tggtcgtcgt caccggctgc
     2221 gtccgggtga cgcggtgctt cctggattcc ggccctgtca cgcttcacgc ttctcctgcc
     2281 cggtgcggtt cgggatccac accacggacg tacctttcgg caccatggcc tcgcacgcga
     2341 cgggctgcgg ccacgtctgc ccggaccgtg cggttcaggc cgtgagacgg aggcgctggc
     2401 cggggtagat caggtccggt ccctcgtcca gcagctcacg gttcagctcg aacagcgcgt
     2461 cggtgccgcc gggtacgtcc gcgcgatcgg cgatcacgga gaggcagtcg cccggctgga
     2521 cgacgtaggt cccggtgccg gcgagctcgt gggagtcggt cgccccggcc gcgtcggacg
     2581 cctcgtggga ggagccctgc gagctgctcg gaccgctgtc cgaccggcgc tgcggtgcgg
     2641 ccttcggcgt ctcgctccgc tggggggtgc tgcccgcctg cgggcccgat gtgccgttcg
     2701 caccgagccg gccgcaggtg ggccaggcgg acagtccctg cgaacgggcg acgcgctcac
     2761 cgacggcgat ctgctgggac cgggtggcga ggtcggcgcg cggtgcgtac tgcccaccgc
     2821 cgtacgcctg ccaggtggag ggtgcgaact gcagtccgcc gtggtagccg ttgccggtgt
     2881 tgatgttcca gcggccgttg ctctcgcagg cggcgatgcg gtcccagtcg gtgcccgccg
     2941 tgacggtcgg cgccatgacg gtcggcgccg tggcggcccg ggcggggaac acctggacgg
     3001 aggcggcctg agtggtggct gcccgggcgg ggacggacgc ggcactgcgg ccggagaggc
     3061 ccagcacgct caggaggacc agcagaagga cgagcgccga ttcgacgggt cgcttggcga
     3121 ggggtgatgc cggcatgacg gtcttcctcc gctgtgctcc gggaactgtt gcaagggcac
     3181 gaacagacaa gccgccgata tgcttttcaa ggggctccga cgcgttccgc ggccgcatgt
     3241 tcacccgcgt gggggccacg gcccggccac ccggccgatg cgggcgggga cgggcccgaa
     3301 gggtcggccg aggccggctc cgcggatgcc ccggtccggc gcaggtcagc tgtgcggagc
     3361 ccgcagcttg gccatctccg cccggacggc gggcagttgg tcgtacagcg catccccggg
     3421 gcagctggtc tggaaggtgt cgcggtggcc ggacaccgcg tggaggtgga ccacctcacc
     3481 ccgctggtac aggctctcgt cgttcgtcga gaccatccgt acggtgctcc gcgggtccgt
     3541 gcccggccgc agcttccacg cgcccacctt cgcgatcccc tcgatgagcg ccttcggcac
     3601 cgggaccccg gggccgaagc tgccgagtgc cgcgacgccc acgctgtgcg cgttgaagcc
     3661 cttggcgtgc gccccgcgca ccgagcgccc caccccgccc gccctgccct cgtagatcgt
     3721 cccgcagcgg tcgacgacga agttgtatcc gatgtcgtcc catccctcac ccgagacgtg
     3781 gtcccgctcc atctcccgca gcatcgtcgg ggcgtcggcg cagtcgtagt cgttggcgtg
     3841 gttggtgtgg tggacgaaga ccgcgttcac cgcccccgtg tacgtcgcgt gctccttgac
     3901 cagggtctcg tccgcgtgcc agtcggcccg gctgacgatc gcgggccgga gggcttcgga
     3961 cggcgccacg ggccgggcca ggaccggctc gggcgcgacg agccggaccg gcgcgtcccg
     4021 gaacaccagg acggccagcg gcacgaccat ggcgcccagg gctgttcggc gaagccacat
     4081 ggggccagcc tgaccgctga ccagcgacgt cgcagtcgcg ccgcacccgg tcgggtgaag
     4141 cgtgccggcg ggccggaagc cctcccgcgc ggcatgcggg ggtcaggacg cggcggcggc
     4201 ggccctgttc tcctcgatga tgcgctcggc gcggtgcggg gaggtgtcga gccgggccag
     4261 cacaccgggg acggcgttgt tggggaggat gagctcgaag agcgcggaga tctccgtgac
     4321 caggtccggg gcgtccgcca tcgactccgt caccagctgc acaccggtcc acgcgccgac
     4381 gaggagccgg gacgtggcga ccgggtcgac gtgcggcagc agctcgcccc gctccttggc
     4441 ctcggtgagc agctccgccc ccagcgtgat ccagtccggc cagcgggtcc cgaacaggct
     4501 ccgggcccgg gggtcgacgg acagccgtat cgaggcgctg agcatgggtt cacggggcag
     4561 ccggtaggcc agcaggagcg cgatgtccac ccactcctgc agcttgaacg tctgcggagt
     4621 cacgccgtcc gaggtcacgg cctcttcgag gacgcccctc gccagctcct ccttggaggt
     4681 gaagtggaag tagagcgcac ccctcgtgag gccggccctc tccaggatcg cggcgatcgt
     4741 ggcagcgtcg taaccgtgct cgtcgaagac ctccgcagcg gcctcgagga agattctgcg
     4801 cgtccggatc gcccgttgct gtcttgccaa ctcgcgctcc cttgacctcg gcttgacgct
     4861 tcttcaaaaa agaccggtga accggtatta tatcagcgcc aggctgccca ctttgcgcca
     4921 tgtccggggg gaccgtgccc gacgtacctg ttttccctca cactccgcgc gccgacgtcg
     4981 ggggcagtga gggtgtccgt atggaatacg tgcacctcag acgtgctgaa gccgttctcg
     5041 tcaccggatg gcgccgcctc gaagatggcg aattctcgct caccctcaac tggcccgcgc
     5101 ccgatggcgg actgccctac gacccccgga tgctcaccca ggccatccgg cagagcggcc
     5161 tgctcatcgc gcacgcggag tacggcgtcc cgctttccca ccacaccctg ctgcactcct
     5221 tcgacttcac cgtagccccc gggttccggg ttcggtcgac cgggccgtcc ccgctgaccg
     5281 tcgggatctc cctcgccgag ccgaagaagc gtggcagggc cgtgagttcc ctcggcatgg
     5341 acatccgcct ctaccaggat gacagcctgg tggcgcgggc ggactgcgac ttcggctgga
     5401 tatcccccgg cgcctaccgc aggctccggg gcgagcacct cggcgccggc tggaacacct
     5461 gggagctccc cgcaccggcc gacccgcgca ccgtccggcg ggcgaccggc accgatgtgg
     5521 tcctggcacc gggcgggcgg ccccaccact ggcggttgcg caacgacgtg gacaacgtcc
     5581 tgctgtacga ccaccccgtc gaccacgtcc cgggactcgt cctgatcgag gccgcccacc
     5641 aggcggccaa cgccgtcctg caccccgcca ccttcgaggc caccaccgtc gacacgtcct
     5701 tcgagcggta cgtcgagctc gaccgcccct gctggatcga ggcggagcgg gcgcccgcct
     5761 ccggccccgg aggagccacg gtgctggtca cggggacgca ggacggcgat acggtcttcc
     5821 ggggccggct gagcggtccg tgcggctgag agcccccgcg gagtcaccgc ccgcgcgtgc
     5881 ggcggctcac tggttgacga agccgccgtc caccggcagg acggttcccg tgaggaacgg
     5941 gcagcggtca ctgagcagcc aggccgccgc gttggccact tcctcgggct cggccgtacg
     6001 gccctgcggc gtcatgctgt tgaccatctc ctccaggccc ggattgcgcc cgaaccagtc
     6061 ggcggtgatc tcactgcgcg tggtgcccgg ggccacggcg ttcaccctga tgccctgttg
     6121 cgcgtactcg tcggcggcgg cccgcgtcag gccgacgacc gcgtgcttgg ccgctatgta
     6181 gggcgcggcg gcgggtatgg ccaccaggcc gcccacgctg gtggtgttca cgatggagca
     6241 gcccccgtcg ttcgacagca tggccgctat ctcgtaccgg agacagttcc agacaccgcg
     6301 cacgttgacg tccatgacgg cgtcgtagac gtcatcgccc atcaggtgca ggggagtccg
     6361 gtcgccgccg agccccgcgt tgttgaacgc cgagtccagg cgcccgtacg tgttcaccgc
     6421 gaagtccacc gcccgggcgg cgtcctccgc cacggtgacg tcacagacca cgtgggacgc
     6481 ctccgcaccc ttgtcccgca actcggccac cagcgcggcc agtcggtcct cccggcgcgc
     6541 ggcgaggacc accgtcgcgc cctcctggga gaacacccgg gccgcagccg cgccgatgcc
     6601 gctgctcgcc ccggtgacga ggacgactct gccgttcaga agatcactca tgggcgcagt
     6661 ctggcaggcc tgttcgaacg ggaccatgcc tgcggagatc cgtggcagca gcagcttcca
     6721 gaaccggggg accgggtact gcggggaccg ctccgcgtcg agacggccga gggcccgcac
     6781 ccccgcgacc gccgccgtca cggtggacca ccacgccctc cgggggaacg cccggggccg
     6841 gtgcgtgtgc ggggtccacc aggtgtcgca gcgggaagag ccgtccgccg gagggcgggg
     6901 cgaggtcgtt ccggaggacg cgcgccgcgt cccccggcgg ccgacttcag cgcgcgcccg
     6961 tcggggaagt ggaagtgcgg cgccccactg ccgaccccgc cccggcggcg ctaccggtga
     7021 gcgaggggag cgggaaacct cccaggtcga ataccccggc ggccgggcgg agcagctccc
     7081 ggcgcgtgcg taccgcgcgg tcctgccggg ccggcccgcc actccggtgc gtgcggggga
     7141 tccggggact tcgggtgccg ctgcccgttc ggtaccggcc ggcaacgacg cagggtgacg
     7201 ttccaaacaa accggttgta ttgttttttt gcccttcccc ggggcccggg ccccgacccc
     7261 gacggattcc gcgatgcccg gacgtcaccg ggcccccgcg ataccgtgcg acatgatcgc
     7321 tatccagttc gaccacttcg gtggccccga ggtcctccag cccgtggaac tggccgcccc
     7381 cgtcccgggc cccggtgagg tgctgctcac cgtcgaggcc gccggggtga acttcgcgga
     7441 cacccaccag acggacggtt cctacctggg ggccgacgcc ctgccgtacg tccccggcag
     7501 cgaggtggtg gcccgcaccc ccgacggcag gcgggtgctc gcccgggtct cgcacggata
     7561 cgcggagcag gtcaccgcca aggagtccgc cctgctggag atccccgagg acctcggcgc
     7621 cgccgaggcg ctcgccctga tggtgcaggg gctgaccgcc tggcatctgc tgcggacctc
     7681 cgcccggctg cgggccggcg agaccgtcgt ggtgcactcc gcggcgggcg gagtgggcag
     7741 cctcgccgta cagctggcca gggagttcgg agcgggccgg gtgctcgccc aggtctcctc
     7801 cccggacaag gaacggctcg tcctggacct cggggcggac gcagtcgtca gctacccgct
     7861 ccaggagaag gcggacgtcg tcctggacgc cgtcggcggt gagctgttcg acctggcact
     7921 ggactccctg gcgtccttcg gccggctcgt gtcctacggc agcgccgccc ggaccggttt
     7981 cacgccggtc gacccggccc ggctggggcg gctcaacgcc gccgtggtgg ggttctggct
     8041 acgccccacc ctggcggcgc cgggcgcggt ggacgggccc ctcgaggaac tcttcggcct
     8101 ggtcgccgac gggcggctca agccggtggc gggcggcagc tacccgctca ccgaggcacg
     8161 ccgcgcccac gaggacatgc tggcccgccg gacggtcggc aaggtggtcc tcgtcccctg
     8221 agccggcccc aggcaggggg tgcgggaagg accgcgagcc gggtcccgca cggggtccgc
     8281 atgcgtgcgg gaggtcatta gggtggcctg atgccatccc tgacctcacg caccccggga
     8341 ccggccccct caggggccgg agccacggac gcggccccgg cccgccccgg ccgcgacccg
     8401 tacttcgaca acgcgaagta cctggccatc gtcctcgtcg cgatggggca ctcctgggag
     8461 ccgctgcccg acagcggacg cgtgatcgag acgttctaca ccttcgtcta cgccttccac
     8521 atgcccgtct tcatcatgat cgccggctac ttctcccgcg gtttcgacct gcggcgcgag
     8581 cgggtgtgga agctcgtcac cagcctgatc gtgccctacg ccgtcttcga ggtggcctac
     8641 acgctcttcg agcgcctcac cggagccccc ggcttcccgc tgagcccgct caccccgtac
     8701 tggctgctgt ggttcctgcc cgcgctcttc ctctggcgtc tcacgacacc ggtctggcag
     8761 acggtccggt ggcccgtcgc ggtgtccctg gtcatcgcgg ccatgggggc ggtcagcagc
     8821 aacatcggcg gcgatctgca gcttcagcgg gtactgcagt tcctgccgtt ctacgtgctg
     8881 ggactgcagc tgcggccggc gcacttcgac ttcgtacgac gccgtgcggt gcgcctcgcc
     8941 tccgtcccgg tctgcgtgat cgccctggcc gcggcgtact gggcggtccc gcgcacgacg
     9001 acctcgtggt tcttccgccg gtacggcgcc gagcagctcg gctcgcccgc ctggacgggt
     9061 gcggtcgtga ccctgctgct gttcggctgc gccgtggtgc tcagcgcctg cttcctcgcc
     9121 tgggttccga gccgcagtat gtggatgacc gccctcggag cgggcaccct gtacggctac
     9181 ctgctgcacg gcttcgtcgt gaagggcgcg atccggctgg acctcttcga ggcggacctg
     9241 gtcgcgacgc cgctcggccg gatcctggtg acggtggtcg cggccgccgt ggtcaccctg
     9301 ctgtgcagtc cgcccgcccg ccgggtgttc cgcttcgtcg tggagccccg gctcgactgg
     9361 gcgaggaagc ccgccccggc aagctgaggg cgggcgggcc caggacgtcg cctcagccgg
     9421 tgacctgcgt cccgccgagg accgtggcgt gctccaggac gtcctccagc ggatcgtcga
     9481 cctggcccgt cgcgatcagc gccacctggg gcgcgttgtg cgagtcggtg tgggtctcgt
     9541 cggcgtggac cgtcccggcc ggaaacacgg acgccagcac ggccacgccg aggacggtga
     9601 gcctgctctt catgtgggtg ccccgtctct tcgtgctcgg gccgggcggc gcgagcgggg
     9661 cgatcatctc gccccgggcg tgtccggggc cgacgactcg agccgcgcgg gagggactgt
     9721 tacagacatt cccggcttcg gcggaagacc ggtaggcccg cgtccggacg caccgcaccc
     9781 ccgggcccgc tgggggcgcc gggggtgcgg tgtcgtcgga cgctgcggtg tcgtcagacg
     9841 gacggccgga tgtcgtcagg cgtgccgagc atggcggacg cgttctccag cggggtgagg
     9901 ggcaccgccg gggcgggcac ctccgccgga cggcaggtga agccgagacg cgtcagcgcc
     9961 cgggtcacct cggccgcgct gaagtcgcgg cggtcctgcc gggtgatgat ctccccgacc
    10021 tgcttgacgg ggtagacgcg gcggctgatg accaccgcgt caccggtgac gggttcgggc
    10081 ttgatgccct tcatcgaatc ctccacttcg ttcttgaaca gatcgaaggg gaagcgggcg
    10141 atgacacagc gcatggtgcc tcaacagggt cggtgagaaa gccggaaagg gtctgccgga
    10201 ctgctgtccg gtgactacgc ggcccggttg gaccggcgca gagcggcagc ggcacgcgcc
    10261 tcgggcgtcg ccgtgttggc gttggagcga cggccctgcg ggggcctgct gcctcgccgg
    10321 cgcgagggcg aaccgctgcc cttgcgctcc gtcagcggcg cggtgatggt cacggggacg
    10381 cccgagggcg cctgcgcccc ggtgatgcgg ctgagctcgg cctcgccgga gcggacctga
    10441 gcgacctgag gggtgatgcc ggcgtccgcc atcagacggg tcatctcgcg gcgctggttg
    10501 ggcagcacca gcgtgacgac gctgccggac tccccggccc gggcggtacg gccgcctcgg
    10561 tgcaggtagt ccttgtggtc gctcggcggg tcgacgttga cgacgaggtc caggttgtcg
    10621 acgtggatgc cgcgcgcggc gacgttcgtg gcgaccagca ccgtgacgtg gcccgtcttg
    10681 aaccggtcca gggtgcgggt gcgctgcggc tgcgacttgc cgccgtgcag cgccgcggcc
    10741 cggacaccgc tgttcagcag gtggtcggtc agcttgtcca ccgcgtgctt ggtgtccagg
    10801 aacatgatca cccggccctc gcgggcggcg atctccgtgg tcgtggcgt
//
