LOCUS       NZ_LMEU01000027        22592 bp    DNA     linear   CON 26-MAY-2024
DEFINITION  Streptomyces sp. Root1319 contig_6, whole genome shotgun sequence.
ACCESSION   NZ_LMEU01000027
VERSION     NZ_LMEU01000027.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root1319
  ORGANISM  Streptomyces sp. Root1319
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1310384)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 1310384)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140604
            Assembly Name                     :: Root1319
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001426615.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 02:19:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,915
            CDSs (total)                      :: 5,857
            Genes (coding)                    :: 5,667
            CDSs (with protein)               :: 5,667
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 190
            CDSs (without protein)            :: 190
            Pseudo Genes (ambiguous residues) :: 0 of 190
            Pseudo Genes (frameshifted)       :: 64 of 190
            Pseudo Genes (incomplete)         :: 160 of 190
            Pseudo Genes (internal stop)      :: 8 of 190
            Pseudo Genes (multiple problems)  :: 38 of 190
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:44:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 356023
            Orig. end                         :: 378615
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMEU01000027.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22592
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="2"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22592
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22592
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12592](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12592
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(139..155)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.32"
                     /tool="antismash"
     misc_feature    complement(140..154)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.04"
                     /tool="antismash"
     misc_feature    170..186
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.24"
                     /tool="antismash"
     misc_feature    complement(173..188)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.91"
                     /tool="antismash"
     gene            complement(324..1109)
                     /locus_tag="ASD26_RS21145"
                     /old_locus_tag="ASD26_10515"
     CDS             complement(324..1109)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959340.1"
                     /locus_tag="ASD26_RS21145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_10515"
                     /product="sugar phosphate isomerase/epimerase family
                     protein"
                     /protein_id="WP_056797973.1"
                     /transl_table=11
                     /translation="MKLAFSTLGVPGLPVADVVRLAAEHGYQGVELRTHPEEPVHPGLT
                     PAERAVVVEEFKGGGVEILTLAGYVRVAAEGDDAPVLAELAELVELARDLGAAHVRVFP
                     GGGQDPAEADATAARRLGAAAPHAADMGVRILLETHDSHRAGADVARVVGTVGHGRIGA
                     LWDVMHTWLADEEPAASHAVLAPHLGYVQVKDIASAEDTAPLALGDGVLPLKACLDVLD
                     ADTWVCWEYEKRWHPGAPELPGLLAAGREHLLRLGAPKQ"
     misc_feature    complement(1094..1108)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.8"
                     /tool="antismash"
     gene            complement(1218..1823)
                     /locus_tag="ASD26_RS21150"
                     /old_locus_tag="ASD26_10520"
     CDS             complement(1218..1823)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452735.1"
                     /locus_tag="ASD26_RS21150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_10520"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_056797970.1"
                     /transl_table=11
                     /translation="MTTPRTDSPLASAAAPADGPRRELLQSVVDVARAIFGAAASSVFL
                     LDEEADELVFQAVSGEGEEFLVGRRFPAGRGIAGWVVTSGEPMVVDDLTTDTSFDRSLA
                     ESTSYVPNALMAAPLISESRILGVLEVLDPSPQARSSVRELDLLAMFARQAAAALRVIT
                     PERAPDGPAAGGRALDGAQREDALRLLVSLEQVLRGTG"
     gene            complement(1804..2682)
                     /locus_tag="ASD26_RS21155"
                     /old_locus_tag="ASD26_10525"
     CDS             complement(1804..2682)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1075: alkaline serine protease, subtilase family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946474.1"
                     /locus_tag="ASD26_RS21155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_10525"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_056797966.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.7e-22, bitscore:
                     76.1, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTTGTATGLGLTWSLRGRGPEDVPVLADAGPPGGLPAEPATGRG
                     VRVCVVDSGVERDHPQVGPLAGSWVVVKDGDTGEITVEPTTTGDTCGHGTACAGIIRRT
                     APDCEIHSVRVLGERFSGTGDVLMAGLRWAVEQRFDVVNLSLSTTRTRFAQELHSLADS
                     AYFARTVIVASAHNTPVESFPWRFASVISVGSHQEDDPGLHLYNPDPPVEFFGPGQNVS
                     VPWLGGRTIRTTGNSFATPYVAGLCARILSAHPKVTVFQLKNALYLSAANVHQGPRPST
                     AAGDTRDDSEN"
     CDS             complement(2686..>3167)
                     /codon_start=2
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156177.1"
                     /locus_tag="ASD26_RS31025"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="PRRTGAAGMRTAVALDAARLELDDGRPQRAASWIASVGEASDLSH
                     ADAVDLEGLRGRLAADQGRPAEAAAHADRAVRASLLTDSPLVQATAELDRARTLSALGR
                     GEDALVSARAARDHFASKGHLPGARRAAGLSRDGTRDVTDETGDTAGPMATTTERS"
     gene            complement(2686..>3169)
                     /locus_tag="ASD26_RS31025"
                     /pseudo=""
     assembly_gap    3170..3177
                     /estimated_length=8
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<3178..5857)
                     /locus_tag="ASD26_RS21160"
                     /old_locus_tag="ASD26_10530"
                     /pseudo=""
     CDS             complement(<3178..5857)
                     /GO_process="GO:0009190 - cyclic nucleotide biosynthetic
                     process [Evidence IEA]"
                     /GO_process="GO:0035556 - intracellular signal transduction
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508342.1"
                     /locus_tag="ASD26_RS21160"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ASD26_10530"
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTCPSCRQELPPDARFCFSCGTPCAVAVAPADDERKPVTVLFCDL
                     VGSTALSGVLDPETLRTVTLRYFEAMSAEIVARGGTPEKFIGDAVMAVFGVPVVREDDA
                     RRALAAALGMRNALARLNEELHSTLGIRLATRIGVNTGQVVAGGDATARQALVSGETVN
                     IAARLEQNAGSGEILIGPDTLFAAGPTVSAEPTGPLRLKGKQDSVDAYRLLALGTDDPE
                     QLRRFDVPFVGRRAEQKALDAALEDTVTNGGAGLLRLTGEAGVGKTRLVREWLLRRSAE
                     GVLAYGAGRCRTYGDHGTLTPLADALRSLPASGGAHRDEDGSEGDARALLSGGLLHDGT
                     PNAPFEDMCAALATELHRAARSRPVLLVLDDWHAAAPLLVRTVERLTSRAGPAGVLVVC
                     VGRPDAADGGPGRPGRETGHLQLTGLPPEDAALLAAGLAGIDGRTGPVDERLLARAEGN
                     PLYLEQLLVGDRTDGAAAAGQPDTDLPPTLQALLGARIGSLARAERNMVDLAAVIGREF
                     TAAELVLLELSARAAEQHASGPVAVGHRAQDLRRVEEALRVLGRRRLVESAPPAADLAA
                     YRFSSGLVHEVTYASLSKRSKADRHAWAAELPSVLRAGDGAVGGHLERAHRYRADLGLL
                     DDRTRQLRDRAATALGRAGAQAAARADLPWAHSLLERAVDLDPAGASSVRRLGEVRVAL
                     GHTEEGAELLRRVRDLESAPVEAAHARLALAVLDPRGAGPGPAATARAVLPVFEAAGDS
                     VGRARAHLRLAQQLQRSGRHEEAERDQARALEHAVLAGAEPERAAALGAIGISLWRGPV
                     PAATAVTRCRALLAAHGGGRPTVRLTLNCPLAVLYALQDRPAEAHGCLAEAEALARKLG
                     FAEADVFLPVFRAAVEALLGDG"
     gene            complement(5965..6207)
                     /locus_tag="ASD26_RS21165"
                     /old_locus_tag="ASD26_10535"
     CDS             complement(5965..6207)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006124648.1"
                     /locus_tag="ASD26_RS21165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_10535"
                     /product="aroma-sacti cluster domain-containing protein"
                     /protein_id="WP_056797963.1"
                     /transl_table=11
                     /translation="MTGPPSSGVAHPSDGGERPPLPAALYEAGLPVDLLTDEQRLVLSE
                     LTPEELAVLLDIKSRLDAVEPEVQAHGEIAGGALF"
     gene            complement(6204..6938)
                     /locus_tag="ASD26_RS21170"
                     /old_locus_tag="ASD26_10540"
     CDS             complement(6204..6938)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046104.1"
                     /locus_tag="ASD26_RS21170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_10540"
                     /product="iron-containing redox enzyme family protein"
                     /protein_id="WP_056797960.1"
                     /transl_table=11
                     /translation="MSAAAPSPSSRLRVTLGLGDSGLRRALDHMWRADGLSPRYLAYLC
                     AMHSVVRASVPLMLRAGERARLLDACGDPLGAPLAAYLAEHVQEEEGHDAWLLEDLASA
                     GRAPAEALGPMPSPDVAGLAGAQYYWIEHHHPVTLLGYIAVLEGYAPSPGLTPRIARLT
                     GLPDAALRTVREHAALDTGHLDELYALLDRLPLTRDQEAAVTVSALHSLDALTQLFVRL
                     GRSAAAPSPRGAGPSSPMGVTP"
     gene            complement(6935..8008)
                     /locus_tag="ASD26_RS21175"
                     /old_locus_tag="ASD26_10545"
     CDS             complement(6935..8008)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046103.1"
                     /locus_tag="ASD26_RS21175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_10545"
                     /product="radical SAM protein"
                     /protein_id="WP_056797957.1"
                     /sec_met_domain="PF04055 (E-value: 1.3e-12, bitscore: 44.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELGELVGQRPFPAAGLLLGLTRACPLRCAHCSTGSTMTVREEPD
                     PGHLLDFVGSFTEEDRPEVVMLTGGEPLLLPALAGELSTLARGAGSRTALLSGMFFARS
                     REIPPAILRAIGQVDHFSASLDVHHEREIPRADVFRAMHRIRETGVAVSFHLTGTGADD
                     PYLADITRAIAEEFDGRVPSLVNEVRPFGRASSWARPARTAPDAGTASPCAMAAWPVVA
                     FDGRVLACCNQDTVDLRPVPAHLDLGHIAVDDWATVRRRAQESPVLRMIRTVGPTHLSA
                     RSSVSRPGSYCDGCRALGADETVAAGAAAGGAAGALLDLAAAHRGAAGGPEGVVRRHGC
                     AAYAPLVVAGAAGRSSR"
     misc_feature    8156..8170
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
     gene            8319..8465
                     /locus_tag="ASD26_RS30345"
     CDS             8319..8465
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511309.1"
                     /locus_tag="ASD26_RS30345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_164494178.1"
                     /transl_table=11
                     /translation="MSENTKPADENETPEVEAHTVLDLQESAVIDRDQPPGSCISVLSV
                     VEG"
     gene            8647..9927
                     /locus_tag="ASD26_RS21180"
                     /old_locus_tag="ASD26_10550"
     CDS             8647..9927
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046101.1"
                     /locus_tag="ASD26_RS21180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_10550"
                     /product="MFS transporter"
                     /protein_id="WP_056797952.1"
                     /transl_table=11
                     /translation="MAAPLRSNRDFRLLWMSGFFAVLGAQTGALALPLLVLKETGSAVQ
                     AGAVGTVSVGAVLITMLPGGVMSDRVERRRLMRLCDAGSLAAVTALTVAVWYGHAPMAL
                     VLLAATAGAVLNSVYAPAAFGLMRAVVPPDQMGTATARLQARTSTVRLVGPLVGGALFG
                     VHPALPFAAQAVGLLLSTVCVALVRTRSKARTRAGSVFSRRELTAGLTFLWQLPYLRTV
                     LLVFGLGMNFAFGALTFTALSVFSEHGRSGLGGGFVITCVSAGALAGALLAPRLGPDRH
                     ARALIVATCWACVLTAGALAWLSSPLAAGLLCALCMCLATIASIGFLSTLLIVTPEDRV
                     GRVQSAASFLSSVVQPFGPLAGGALLTALGSRSAFGVIGCVLAVSALVVTFAPSVRSGA
                     APPAGEGTGAPGPGSEPAGAARARPGD"
     gene            10001..12592
                     /gene="lanKC"
                     /locus_tag="ASD26_RS21185"
                     /old_locus_tag="ASD26_10555"
     CDS             10001..12592
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018959331.1"
                     /locus_tag="ASD26_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_10555"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_056797948.1"
                     /sec_met_domain="micKC (E-value: 8.4e-207, bitscore: 685.0,
                     seeds: 18, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGIQETQLYCLADRRYYETPARLPDEATRYPLDAAPPPAGWRRA
                     AAGLWTSLLPEDREPAEQGWKIHVSTVPDEAAATLRDTARICLRHGVPFKFLRSEQALL
                     LMSGKYMARSGAGKFLTLYPQDETVFLTLVDELSRALDGRRGPYILSDLRIGDAPVYVR
                     YGAFVARWCRDEEGERVPALRHPSGELVPDVRGVVFRVPEWVTVPEALRPHLAARAAAG
                     DATFPYTVTEALQFSNAGGIYLARHRDTGRQVVLREARPHCGLDAVGDDAVLRLHREHR
                     ALTALAGLDCVPEVYGVRTVWEHHFLIEEHIEGNTLIEEIITRFALVRGAGSPAELAPY
                     VAWVDSVTAGLTRALAAVHARGLRFGDLHPSNVIVRPDGGVVLIDFEYATALDDQDTPP
                     AGAPGLQAPPGTPGAEADAYALWATWLTMLMPLMEMAGHDRAKAVTLERWARTRYGLTP
                     DAGPHRPAAVRAVSGPHSREHEIAALLDGPAPDWRELRARLLAGIHAGATPERRDRLFP
                     GDPQAFATGGTDLAHGAAGVLYALHRVGAPVPDAWTDWLAAAARRRDPAAPGGLFDGLP
                     GTAVVLAGLGRPADGREILERALAAAPPNTSADLFTGRAGVALAALRLARTGGSAPDPE
                     LLESAVRTAWSLDCLVRGEPAGGLRAPDSAGLLRGLSGAALLHLELHALTGEDWLLKAA
                     RTALEREAGHCVTMPDGTVQVKDGRRHLLYLDQGSGGFALVAQAYLARHEAPGLAALLP
                     GVRQGCVLEFVREPGLFTGRAGLVATAGQLGGQDRTDASVLASVRNLSWHLLADGDRLL
                     VPGARLRRCSADLATGAAGLLLALHFLSGAGTDGPGERSTSAGLLELLTLG"
     gene            complement(12684..14507)
                     /locus_tag="ASD26_RS21190"
                     /old_locus_tag="ASD26_10560"
     CDS             complement(12684..14507)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608633.1"
                     /locus_tag="ASD26_RS21190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_10560"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_056797944.1"
                     /transl_table=11
                     /translation="MTRSPARPGPTGAVYFSLLGPLTAVVDGRPLPLGPRKQRLVLATL
                     LSRPNTPVPVDVLTDVVWPDAPPRTARKNLQVYISAARTLFGAAGDRDRVVHGCGGYRL
                     RIGEAELDTLRFGALARSGRAAGERGDLRTAARLLREALDLWGERQPLHDLRDSAGVAE
                     EAERLESRCLTVYEDWAEAEIETGRAAVAVDGLRDLVERHPLRERLRAAWMNSLHQSGR
                     QAEALAVYDDYRQLLARELGLEPSPAMAALYADMLGRGRAARTTTPRDSAGGVSLPAAA
                     RDFTGRRDELREVLDESGAAEGGVLIVSGPAGSGKSALAVRAAHLLADGFPDGRVHVRV
                     RREDGTARTRAEVLGELGRLCGARVPPGGPEAEDAWQDWLSRHRALIVLDDVPDEASVR
                     GLLPRSGRCSVLLTARGQLAGLAPAHRVALTALADGEALELLGRLIGAGRVRTDPAAAL
                     RIVRACGALPLAVTVSGMRLAVLRHLPLAEYASRLDDPSAALDELVAGDVSVRSRIASG
                     WQDLTEQNREALARLAGFAHDGGFTLDRAMDVLGCGERAAIRTVESLLDTGAVTSPAGE
                     VTAHAALYEVPRLLCLYARERTGSDLSLVRG"
     CDS             complement(14507..14713)
                     /gene="allorf_0370530_0370736"
                     /locus_tag="allorf_0370530_0370736"
                     /protein_id="allorf_0370530_0370736"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPSARMGAAPLNIRPDGGSTAQHGGTGRFGSGAAPEDAGGAPMCP
                     GRRDGRIGGCTAACRPSPPQEAR"
     CDS_motif       complement(14552..14713)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MPSARMGAAPLNIRPDGGSTAQHGGTGRFGSGAAPEDAGGAPMCPGRRDGRIGG"
                     /locus_tag="allorf_0370530_0370736_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14507..14551)
                     /prepeptide="core"
                     /locus_tag="allorf_0370530_0370736_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.50"
                     /molecular_weight="1450.6"
                     /monoisotopic_mass="1449.7"
                     /core_sequence="CTAACRPSPPQEAR"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPSARMGAAPLNIRPDGGSTAQHGGTGRFGSGAAPEDAGGA
                     PMCPGRRDGRIGG"
                     /leader_location="[14551:14713](-)"
     gene            complement(14732..17659)
                     /locus_tag="ASD26_RS21195"
                     /old_locus_tag="ASD26_10565"
     CDS             complement(14732..17659)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018488912.1"
                     /locus_tag="ASD26_RS21195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_10565"
                     /product="AAA family ATPase"
                     /protein_id="WP_056797940.1"
                     /transl_table=11
                     /translation="MRATSPVTVGRDGEIGLLSSALDAVQRRSGRALFLLGEAGIGKSR
                     LVGECAYRAYELGMPVLRGRASSTGLVVPYRPLVEALSSHFRAAGTPTDPELVPYHPAL
                     ARLVPEWRRGASPGYPETVVELAEALLRLLSVLGRDTGCVILLEDLHDSDTETVAVVEY
                     VIDNLAGLPILLLGTLRPEAGAALDLVRSAERRQTAAVRELRALGDDEVRLLTGACLET
                     PPERIPPVVQHRLAERAAGNPYLVELLLADLLDTGQLRRTDAGWDAAEQPDCALPSGIL
                     RSWTRRLDRLDEPVRDLLLTAATLGSQFSVTVLQTVTGFEDRALFTHLRSAVEAGVIAP
                     DGAAPDRYTFRHALTAEALVSSLAPAERAALARRAAATVEHSGQPLDEDRRQLVATLEL
                     AAGNRSGAALQFAEAGRRLLASGTHGSAVVLLERAHSLAAESDRAAIAEDLAVARAESG
                     DLDGALALTDTLPPVPARSEAAARRGDAHIKIAWVAVMAERVSDAARQISAAHGLLGPS
                     PSPARRAALVVVDGHLSLLPGEDRGEPGETERAALLAAETAEAEGLPVVACQAWQLLAL
                     LSREKGFDAADACLERMLTLSTEHSLPLWRVEAMVRLGANGFMRTGDAARLHSARAAAT
                     ELGALLLTRTVDGLLAMNAVMCARWDEAQEIIDRSAEASARVGNLSAHRYLLLAGATMA
                     AHRGRRREMDRSLAAFRRAGGEQSLLVPLGLGLCRAIGALLDEDRGRALSDLDAALGWE
                     RDHPSYFYLSGRYGLRPLLRILAGEADRREYDAVTASPGAGLAWNRQFMDLAEAVLLGR
                     DGDRAGAARLMAAFEARSAAFPVARHLGLRLVADAARADGWGEPVAWLRTAEEFFYGAG
                     VQPVAAACRAALRQAGASVTQHRGGRDRIPSSLRTTGVTPREYEVFVLLAERPGNQQIA
                     RRLSISPRTVEKHMASLLSKTGRENRAALCEYAAEYAAEHTVEHA"
     misc_feature    complement(16883..16885)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(17740..17937)
                     /locus_tag="ASD26_RS21200"
                     /old_locus_tag="ASD26_10570"
     CDS             complement(17740..17937)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015608631.1"
                     /locus_tag="ASD26_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_10570"
                     /product="hypothetical protein"
                     /protein_id="WP_056798749.1"
                     /transl_table=11
                     /translation="MTQISESAMQAAVTAHEGAPEHPAGRISLGSSGGALGLRSRLLSV
                     SEGDIGYSHDLPFTTMTNPL"
     CDS             complement(17937..>18466)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=2
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577223.1"
                     /locus_tag="ASD26_RS31030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_277922357.1"
                     /sec_met_domain="LANC_like (E-value: 2.4e-11, bitscore:
                     39.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GGPRYRAAGLRALRRAVSGAGAGQAWCDGATGVALAVADSPDALA
                     DPELSGWLSGRAGALAEAVPPANDSLCHGELGVLELLGHGALPGLRAPWVRRTGTLLAA
                     ADRAGPQCGTPGNVPHPGLLTGLSGIGHGLLRAGFPDRIGSALLVQPSTGGTTGTNRSS
                     FPAPLSTSQMRQR"
     gene            complement(17937..>18468)
                     /locus_tag="ASD26_RS31030"
     assembly_gap    18469..18479
                     /estimated_length=11
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     CDS             complement(<18480..18780)
                     /codon_start=2
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007450767.1"
                     /locus_tag="ASD26_RS31035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_242413201.1"
                     /transl_table=11
                     /translation="MTLTEVGFLLDDHQVLDWAGPATRLSSAAGSAEDGFGVRGGAAGG
                     LVSLLAVHRATGRPEAWRGAERCAERIAAAPLPEAGGFADGAAGVGWALLRFAAAG"
     gene            complement(<18480..>18782)
                     /locus_tag="ASD26_RS31035"
     assembly_gap    18783..18791
                     /estimated_length=9
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<18792..>20965)
                     /locus_tag="ASD26_RS21205"
                     /old_locus_tag="ASD26_10575"
                     /pseudo=""
     CDS             complement(<18792..20965)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380885.1"
                     /locus_tag="ASD26_RS21205"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="ASD26_10575"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /pseudo=""
                     /sec_met_domain="DUF4135 (E-value: 1.8e-106, bitscore:
                     352.6, seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPWWLPGVVGQRPAAEPDWAVFVRDVVAGAPRDAVAADREYPGL
                     SGFALIMAPFAERAVDRAVEQAADQAWGRAADRPSAPDDVPGAGPVACPAAVLDDFRSH
                     LTGRLARLAARTLVLELHEARQEGRLGGDGTRERFRDFLRLTARRSGLASLVTGYPVLA
                     RIVARTSMNAADSFAEMFGRLAADRELLQASGLLGDRGAGVLGDRGPGGLTGVEAGAGD
                     SHRGGRSVMLLRFADGTRLVYKPRPLAAHQHFNTLVEWFNSLPATPDLRTPRVLDRGAY
                     GWVEFVEERPCDSAAETTRFYRRQGALLALLHVLDGTDLHHENLIACGPHPVLVDVETL
                     FHPPLVPARSADPAARALHASVHRVGLLPQLLVGDTTALDMSAIGGGGAGSSPIETAGW
                     DAAGTDRMRLVRTAGRFTESANRPRLGGIPADPSSYTDALCDGFRAGYTAVGDARDELL
                     GPKGLLRLFAQDEIRVVPRPTWTYTTLLDESTHPDLMRDATERHRIFALLRTPSLGTTA
                     LPGLEDEEITELWNGDVPVFAGRPDSTDLWSGTGRRVPGPEGVTGLVRVEAKVRALDTV
                     GRLDQEHIIRAAMVSTSPEPAHRAGSGHRPPAVDTAPEPEHLLSVARSVGDQLVSLAFR
                     HEGRTNWIGLELLGERYWRLTPMAADLAGGYTGPALFLAQLASLTGAARYADAAREALA
                     PVPGLLDALHERVDDLGLLGSGAFAGLGGI"
     gene            complement(21395..22459)
                     /locus_tag="ASD26_RS21210"
                     /old_locus_tag="ASD26_10580"
     CDS             complement(21395..22459)
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380887.1"
                     /locus_tag="ASD26_RS21210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_10580"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_056797937.1"
                     /transl_table=11
                     /translation="MTVTLADVAARARVSPATVSRVLNGNYPVAASTRDRVLRAVDDLD
                     YVLNGPASSLAAATSDLVGILVNDIADPFFGIMAGAAQSEIGGPGDGSGRAGGEKLAVV
                     CNTGGSPERELTYLTLLQRQRAAAVVLTGGALEDPAHQAVMAAKLAKLADAGTRIVFCG
                     RPPLPDSDAVVAALAFDNRGGGRRLTEHLLELGHRRIGYVAGPLERTTTRHRLEGHREA
                     MKAAGLYADEESLTVHGPYDRRSGYDATLELLRRAPEVTAVVAANDTVALGAGAAIREH
                     GLRIPEDVSVAGFDDLPFSVDAVPALTTVRLPLFEAGARAGRLAMGKETPPPGGIATIE
                     AELMVRGSTAPPRG"
     misc_feature    complement(22535..22546)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.83"
                     /tool="antismash"
     misc_feature    22538..22558
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 18.75"
                     /tool="antismash"
ORIGIN
        1 tgtccgtgga ggtgccggcc gcccgggcgg cgccgggaac ggcgacgacg ccggtcgccg
       61 ccgcggcggc ggtgaccgcg gtggcggtga ggagggtgcg tctggaggtg cggtggtgca
      121 cgtgagcccc ttccggtact gaaagaaact tccaagaagg tacggatata tggaaagtaa
      181 ctaccagtca agggggccgt ccgagaaagg gactgacacg cgggagggcg ggtggacatg
      241 cccggacatg gtccacgccc ccgccgcgcg acggcgggag ccgcagccgc cgcaccccgc
      301 ccgcggcggc ccgggtccga ggactactgc ttcggcgcgc ccagacgcag caggtgctcc
      361 cgccccgccg ccagcagccc cggcagctcc ggagcgccgg ggtgccagcg cttctcgtac
      421 tcccagcaca cccaggtgtc ggcgtccagc acgtccaggc acgccttcag cggcagcacc
      481 ccgtcaccga gggccagcgg cgcggtgtcc tcggccgacg cgatgtcctt cacctgtacg
      541 tatcccaggt gcggggcgag caccgcgtgg ctggccgcgg gctcctcgtc cgcgagccag
      601 gtgtgcatga cgtcccagag cgcaccgatc cggccgtgcc cgaccgtgcc caccacccgg
      661 gccacgtcgg ccccggcgcg gtgcgagtcg tgggtctcca ggaggatccg tacgcccatg
      721 tcggcggcgt gcggagccgc ggcgccgagc cgccgggcag ccgtcgcgtc ggcctcggcc
      781 gggtcctggc cgccgcccgg gaacacccgg acgtgcgccg ctcccaggtc gcgggccagc
      841 tccaccagct cggcgagctc ggccagcacg ggcgcgtcgt caccctcggc ggcgacccgc
      901 acgtacccgg cgagggtcag gatctcgacc ccgcccccct tgaactcctc gacgaccacg
      961 gcccgctcgg ccggggtgag ccccgggtgc acgggctcct cggggtgggt gcgcagctcc
     1021 acgccctggt acccgtgttc ggcggcgagc cgcaccacgt cggccacggg caggcccggc
     1081 actccgaggg tcgagaaagc gagcttcacg aatatgtcct tcccctggtc agctgcgggt
     1141 gcccggtacg gcgccctcac cgactcctgc ccgccggtcc ggccggcacg cctgtgcgcg
     1201 gctgccgggg cgggcgctca gccggtgccc cgcagcacct gctcaagact aacgagcagc
     1261 ctcagcgcgt cctcgcgctg cgctccgtcc agcgcccggc cgccggccgc cgggccgtcc
     1321 ggggcgcgct ccggggtgat cacccgcagg gccgcggcgg cctgccgggc gaacatcgcc
     1381 agcaggtcca gctcgcgcac gctcgaccgg gcctggggcg acgggtcgag cacctccagc
     1441 accccgagga tccgggattc gctgatcagc ggggccgcca tcagcgcgtt cggcacgtag
     1501 gaggtggact cggccagcga acggtcgaag gacgtgtcgg tggtcagatc gtccaccacc
     1561 atcggctcgc ccgaggtgac cacccagccg gcgatgccgc gcccggcggg gaagcggcgg
     1621 cccacgagga actcctcgcc ctccccggag acggcctgga agaccagctc gtccgcctcc
     1681 tcgtcgagca ggaagaccga gctggccgcg gcgccgaaga tcgcgcgtgc cacgtcgacg
     1741 acggactgga gcagctcgcg ccgggggccg tcggccgggg cggccgcgga cgcgaggggg
     1801 gaatcagttc tcggagtcgt cacgggtgtc tcctgccgct gtggaaggac gcgggccctg
     1861 gtgcacgttg gccgcggaca gatagagggc gttcttgagc tggaagaccg tcaccttggg
     1921 gtgcgcggag aggatgcggg cgcagagccc ggcgacgtac ggcgtggcga agctgttgcc
     1981 ggtggtgcgg atcgttctgc cgcccagcca cggcacggac acgttctggc cgggtccgaa
     2041 gaactccacc ggggggtccg ggttgtacag gtggagcccg gggtcgtcct cctggtggct
     2101 gccgacggag atcaccgagg cgaaccgcca ggggaagctc tccaccgggg tgttgtgggc
     2161 cgaggccacg atgaccgtac gggcgaagta ggcgctgtcg gccaggctgt gcagttcctg
     2221 cgcgaaccgg gtgcgggtgg tcgacaggct caggttcacc acgtcgaagc gttgctccac
     2281 ggcccagcgc agcccggcca tcaggacgtc gcccgtcccg gagaagcgct cgccgagcac
     2341 ccggacgctg tggatctcgc agtcgggggc ggtcctgcgg atgattcccg cacacgccgt
     2401 cccgtgtccg caggtgtccc cggtggtcgt cggctcgacc gtgatctcgc cggtgtcccc
     2461 gtccttgacc accacccagg acccggcgag cggcccgacc tgcggatggt cgcgctccac
     2521 ccccgaatcc accacgcaca cgcgtacgcc ccgccccgtg gcgggttccg cgggcagacc
     2581 gcccggcggt cccgcgtccg ccagtacggg cacgtcctcg gggccgcgcc cccgcaggct
     2641 ccaggtcagt cccagtcctg tcgccgttcc cgtggttccc atcggtcagc tcctctccgt
     2701 cgtcgtggcc atgggcccgg ccgtgtcccc ggtctcgtcg gtcacgtccc gggttccgtc
     2761 ccgggagagg ccggcggccc ggcgggcccc cggcaggtgc cccttgctcg cgaagtggtc
     2821 ccgtgcggcc cgggcggaga ccagggcgtc ctcacccctg ccgagtgcgg acagcgtcct
     2881 ggcccggtcc agctcggccg tcgcctggac cagcggggag tcggtgagca gcgaggcccg
     2941 gaccgcccgg tccgcgtggg cggcggcctc ggccggacgc ccctggtccg ccgcgagccg
     3001 gccccgcagg ccctccaggt cgaccgcgtc ggcgtggctc aggtccgacg cctcgccgac
     3061 ggaggcgatc caggacgccg cccgctgcgg tcggccgtcg tccagctcca gccgggccgc
     3121 gtccagcgcg acggcggtcc gcatccccgc cgcaccggtg cggcgggggn nnnnnnnagc
     3181 cgtcgccgag cagcgcctcg accgccgccc ggaacaccgg caggaagacg tccgcctcgg
     3241 cgaacccgag ctttcgggcc agcgcctccg cctcggccag gcagccgtgc gcctcggcgg
     3301 gccggtcctg gagcgcgtac agcaccgcca gcgggcagtt gagggtgagc cggaccgtgg
     3361 gcctgccccc gccgtgtgcc gccagcaggg cccggcagcg ggtcaccgcc gtggcggcgg
     3421 ggaccgggcc gcgccacaag gagatcccga tggccccgag ggccgcggcc cgctccggtt
     3481 ccgccccggc gagcaccgcg tgctccaggg cccgtgcctg gtcgcgttcc gcctcctcgt
     3541 gacggccgga ccgctggagc tgctgggcga gccggaggtg cgcccgcgcc cggccgaccg
     3601 agtccccggc cgcctcgaag accggcagca ccgcccgcgc cgtggccgcg gggcccggcc
     3661 cggccccccg ggggtccagc accgcgaggg ccagccgggc gtgcgcggcc tccaccgggg
     3721 cggactccag gtcccgtacc cggcgcagca gttcggcccc ttcctcggtg tgcccgagcg
     3781 ccacccgtac ctcgccgagc cgccgcaccg atgaggcgcc ggcggggtcc aggtccaccg
     3841 cccgctccag caggctgtgt gcccagggca ggtcggcccg ggccgcggcc tgtgccccgg
     3901 cccggcccag tgcggtggcg gcgcggtccc gcagctgccg ggtgcggtcg tcgagcagtc
     3961 ccaggtcggc gcggtagcgg tgggcgcgct ccagatggcc cccgacggcg ccgtccccgg
     4021 cccgcagcac actgggcagc tcggccgccc aggcgtgacg gtccgccttg gagcgtttgg
     4081 acagcgaggc gtacgtcacc tcgtgcacca gcccgctgct gaaccggtac gcggccaggt
     4141 ccgccgccgg cggggcggac tccaccaggc gccgccggcc cagcaccctc agcgcctcct
     4201 cgacgcgccg caggtcctgc gcgcggtggc cgacggccac cgggccggac gcgtgctgct
     4261 cggcggcccg tgcggacagc tccagcagca ccagctccgc ggcggtgaac tcccggccga
     4321 tcacggccgc caggtcgacc atgttccgct ccgccctggc cagcgacccg atccgggcac
     4381 cgagcagggc ctggagcgtg ggcggcagat cggtgtccgg ctgtccggct gccgccgccc
     4441 cgtccgtacg gtcaccgacc aacagctgtt ccaggtagag gggattgcct tcggcacggg
     4501 ccaggagccg ctcgtccacc gggcccgtcc ggccgtcgat gccggccagc ccggcggcga
     4561 gcagggccgc gtcctccggt ggcagaccgg tgagctggag gtgccccgtc tcgcggcccg
     4621 gccggccggg accgccgtcc gccgcgtccg gacggcccac gcacaccacc agcacccccg
     4681 cgggccccgc ccggctcgtc agacgctcca ccgtgcgtac gaggaggggc gccgccgcgt
     4741 gccagtcgtc caggaccagg aggaccgggc ggctccgggc cgcccggtgc agctccgtgg
     4801 ccagcgcggc gcacatgtcc tcgaagggcg cgttcggtgt gccgtcgtgc agcaggcccc
     4861 ccgagagcag ggccctcgcg tccccctcgg acccgtcctc gtcccggtgc gccccgccgg
     4921 acgcgggcag ggagcggagg gcgtcggcga ggggggtgag cgtgccgtgg tccccgtagg
     4981 tgcggcaccg tccggcaccg taggcgagga cgccctcggc cgagcgccgc agcagccact
     5041 ccctgaccag ccgggtcttg ccgacccccg cttccccggt gagccgcaga aggcccgcgc
     5101 ctccgttcgt cacggtgtcc tccagggccg cgtccaaggc tttctgttcg gcacggcgtc
     5161 cgacgaacgg gacgtcgaaa cggcgcagtt gttccgggtc gtccgtgccc agcgcgagca
     5221 gccggtaggc gtccacgctg tcctgcttgc ccttcagccg gagcggcccg gtgggctccg
     5281 ccgacaccgt cgggcccgcg gcgaacaggg tgtccgggcc gatgaggatc tcgccggatc
     5341 ccgcgttctg ctccaggcgg gcggcgatgt tgacggtctc cccggacacc agggcctggc
     5401 gggccgtcgc gtcaccgccg gccaccacct ggccggtgtt gacaccgatc cgggtggcca
     5461 gccggatgcc gagcgtggag tgcagctcct cgttgagacg ggccagggcg ttccgcatcc
     5521 ccagggccgc ggccagggcg cggcgggcgt cgtcctcccg gaccaccgga acgccgaaga
     5581 ccgccatcac ggcgtccccg atgaacttct ccggggtgcc gccccgcgcc acgatctccg
     5641 cgctcatcgc ctcgaagtac cgcagtgtca ccgtgcgcag ggtctccggg tccagtacgc
     5701 cggacagcgc cgtggagccg acgaggtcgc agaagagcac cgtcaccggc ttgcgttcgt
     5761 cgtcggccgg cgcgacggcg acggcgcacg gcgttccgca ggagaagcag aaccgggcgt
     5821 ccggcggcag ctcctgacga cacgaggggc aggtcatgac gagtccttca cttcgggacc
     5881 ggacagcgct gcccggcggg gcgtcggccg gcgcagccgt ggcgtaccgg ccgcaccggc
     5941 cccggccggc ctctccgagg gcctctagaa cagggcgccg ccggctatct cgccgtgtgc
     6001 ctggacctcg ggctccacgg cgtcgagcct gctcttgatg tcgaggagca cggcgagttc
     6061 ctcgggagtc agctcgctga gtacgaggcg ctgttcgtcg gtgagcaggt ccacgggcag
     6121 ccccgcctcg tacagtgcgg cgggcagcgg gggccgttcc ccgccgtcgg acgggtgggc
     6181 aaccccgctg ctcggtggtc cggtcatggt gtgactccca tcggtgagga aggtccggcc
     6241 ccccgcggcg acggcgccgc cgctgagcgc ccgagccgga cgaagagctg ggtgagggcg
     6301 tcgagggagt gcagcgcgct gaccgtcacg gccgcctcct ggtcccgcgt cagcggcagc
     6361 ctgtccagca gtgcgtacaa ctcgtcgagg tggcccgtgt cgagcgcggc gtgttcccgt
     6421 acggtccgca gggcggcgtc gggcaggccg gtcagacggg cgatgcgggg agtcaggccg
     6481 ggcgagggcg cgtagccctc cagcacggcg atgtagccga gcagcgtcac cgggtggtgg
     6541 tgctcgatcc agtagtactg ggcgccggcg agtccggcga cgtccggtga cggcatcgga
     6601 ccgagcgcct cggcgggcgc ccggcccgcc gatgcgaggt cctccagcag ccaggcgtcg
     6661 tgcccctcct cctcctggac gtgttccgcc aggtaggccg ccagcggggc gcccagcggg
     6721 tcgccgcagg cgtccagcag ccgggcacgc tccccggccc ggagcatcag cggaacggag
     6781 gcccgcacca cggagtgcat ggcgcagagg tacgccaggt agcgcggcga caggccgtcg
     6841 gcccgccaca tgtggtccag cgcgcgccgc agcccgctgt cccccagccc cagggtgacg
     6901 cgcagtcgcg acgacgggct cggcgcggcg gcgctcaccg ggagctccgt ccggcggcgc
     6961 ccgcgacgac gagtggtgcg tacgccgcgc agccgtgccg ccggacgacc ccctccgggc
     7021 ctcccgccgc cccccggtgc gcggcggcca ggtccagcag agcccccgcc gccccgcccg
     7081 ccgcggcccc ggcggccacc gtctcgtcgg cgcccagtgc ccggcagccg tcgcagtagg
     7141 aaccgggccg ggacacggag gaccgggcgg acagatgggt gggaccgacc gtacggatca
     7201 tgcgcagcac cggggactcc tgggcgcgcc ggcgcacggt cgcccagtcg tcgaccgcga
     7261 tgtgcccgag gtccagatgg gcggggacgg gccgcaggtc cacggtgtcc tggttgcagc
     7321 aggccagcac cctgccgtcg aaggcgacca cgggccaggc ggccatcgcg cagggggacg
     7381 ccgtgcccgc gtccggcgcg gtgcgggcgg gccgcgccca ggacgaggcc cgcccgaacg
     7441 gccgcacctc gttgaccagg gacggcaccc gcccgtcgaa ctcctcggcg atggcccggg
     7501 tgatgtccgc gagatagggg tcgtcggcgc ccgtcccggt gaggtggaag ctcacggcca
     7561 cgcccgtctc ccggatcctg tgcatggcac ggaagacgtc ggcccgcggg atctcccgct
     7621 cgtggtgcac gtcgaggctg gcggagaagt ggtcgacctg cccgatcgca cgcaggatcg
     7681 ccggcgggat ctcccgggag cgggcgaaga acatgccgct gagcagcgcg gtgcgcgagc
     7741 cggcaccacg ggcgagggtg ctcagctccc cggcgagcgc gggcaggagc agtggctccc
     7801 cgccggtcag catcacgacc tcgggacggt cctcctcggt gaaggagccc acgaagtcca
     7861 gcaggtggcc cgggtccggc tcctcccgca cggtcatggt cgatccggtg gagcagtggg
     7921 cgcaccgcag ggggcaggcc cgggtgaggc cgagcagcag accggcggcg gggaagggcc
     7981 gctgtccgac gagttcgccg agttccatgc ggggccgcct ccttcagagg gctgaggcgc
     8041 gtcgggcgcg tacccaggct gcgccgcgcc ggttcggcga cggtccgccc ccgcttcggg
     8101 agcggtatgg gcgcaggtcg gccgggggcc cgagcccgcc gcggacccgg gggacgggcc
     8161 gtccggccgt ggtgaacggg ccccataccg tcgccatacc gctgccgaag cgttcgccag
     8221 gccaccgctc ctaactttct cggcaacggc aggcagcggg ccgcggcgga cagccgagga
     8281 ctccgggccg gcacagcgac gagtggacgg agaccaccat gtccgagaac acgaagcccg
     8341 ccgacgagaa cgagaccccc gaggtcgagg cacacaccgt cctggacctc caggagtccg
     8401 cggtcatcga ccgcgaccag cctccgggca gctgcatcag cgtgctgagc gtcgtcgagg
     8461 gctgatccga cgagccgggc cgtgtgccac gtgcgaccgg gggcactgcc ccgccgccgt
     8521 ggcgcccggc cggagacggg gcggcctccg tgacgcacgg aggccgcccc gccccgctgt
     8581 ccggccccgt cggccctcgg gccgccgccg ccgcgctcca gccgtcccga cgaacgggag
     8641 ctcccgatgg ccgcaccgct ccgctccaac agggatttcc ggctgctctg gatgagcggc
     8701 ttcttcgccg tcctgggtgc ccagacgggt gccctcgccc tgcccctgct ggtcctcaag
     8761 gagaccggct cggcggtgca ggccggcgcc gtggggaccg tgtccgtcgg cgccgtgctg
     8821 atcacgatgc tgcccggcgg agtcatgtcc gaccgggtcg aacgccgccg gctgatgcgg
     8881 ctgtgcgacg cgggaagtct cgccgcggtc accgccctca ccgtcgccgt ctggtacggg
     8941 cacgccccta tggcactcgt cctgctggcc gcgaccgcgg gagccgtgct caacagcgtg
     9001 tacgcccccg ccgccttcgg cctgatgcgc gcggtcgtgc cacccgacca gatgggcacg
     9061 gccaccgcgc ggctccaggc gcgcacctcc acggtccggc tggtcggccc cctcgtcggc
     9121 ggtgcgctgt tcggcgtcca ccccgcgctg cccttcgcgg cccaggccgt cggactgctc
     9181 ctgtcgaccg tctgcgtggc gctcgtacgc acccgctcga aggccaggac ccgggcgggc
     9241 tcggtgttca gccgccggga actcaccgcc gggctcacct tcctgtggca gctcccgtac
     9301 ctgcgcacgg tgctgctcgt cttcggcctc ggcatgaact tcgcgttcgg cgccctcacg
     9361 ttcacggcgc tcagcgtctt ctccgagcac ggcaggtccg gtctcggcgg cggcttcgtc
     9421 atcacctgcg tgtccgcggg cgcactcgcc ggcgcgctgc tcgcgccccg gctcggcccc
     9481 gaccggcacg cccgggccct catcgtcgcc acctgctggg cctgtgtgct gaccgccggt
     9541 gcgctggcct ggctcagcag cccgctggcg gccggactgc tgtgcgcgct ctgcatgtgc
     9601 ctggcgacga tcgccagcat cggattcctg tcgaccctgc tgatcgtcac tccggaggac
     9661 cgtgtcggca gggtgcagag cgcggcgagc ttcctgtcct cggtcgtcca gcccttcgga
     9721 ccgctcgcgg gcggcgccct gctgaccgcc ctgggcagcc gctccgcctt cggcgtgatc
     9781 ggctgcgtgc tggccgtgtc ggcgctcgtg gtgacgttcg ccccctcggt ccgctccggg
     9841 gcggcaccgc cggccggcga ggggacgggg gcaccgggcc ccggctccga acccgccgga
     9901 gcggcccgcg cccgcccggg ggactgaccc ggaacggccg tcgtccagtc cgaccgaccc
     9961 acgacgccgc cggccccggc gcgctccgag gaggaaagcc gtgcccggca tccaggagac
    10021 ccagctctac tgcctcgcag accgcaggta ctacgagacc ccggcacggc tgccggacga
    10081 ggcgacccgc tatccgctcg acgccgcacc gccaccggcc ggctggcggc gcgccgccgc
    10141 gggcctgtgg acctcgctcc tgcccgagga ccgtgaaccg gccgagcagg gctggaagat
    10201 ccacgtctcc accgtgccgg acgaggccgc ggcgaccctg cgcgacaccg cccggatctg
    10261 cctccggcac ggggtgccgt tcaagttcct gcgcagcgag caggccctcc tgctgatgtc
    10321 cggcaagtac atggcccgca gcggcgccgg gaagttcctc acgctctacc cgcaggacga
    10381 gaccgtcttc ctgacgctgg tcgacgagct gtcccgggcc ctggacggcc gccggggccc
    10441 gtacatcctc agcgacctgc gcatcggcga cgccccggtc tacgtccggt acggggcgtt
    10501 cgtcgcacgc tggtgccgcg acgaggaggg cgaacgcgtc cccgccctgc ggcacccgtc
    10561 gggcgaactg gtgcccgacg tacgcggtgt ggtgttccgg gtgcccgaat gggtcaccgt
    10621 ccccgaggcg ctgcgcccgc acctcgccgc ccgggccgct gcgggcgacg ccaccttccc
    10681 ctacaccgtg accgaggccc tccagttctc caacgccggc gggatctacc tggcccggca
    10741 ccgggacacc ggccggcagg tggtgctgcg cgaggcccgc ccgcactgcg gcctcgacgc
    10801 ggtgggggac gacgcggtgc tgcgactgca ccgcgagcac cgggcgctga ccgcgctggc
    10861 cggactggac tgcgtgcccg aggtgtacgg ggtccggacc gtgtgggagc accacttcct
    10921 gatcgaggaa cacatcgagg ggaacaccct catcgaggag atcatcaccc ggttcgccct
    10981 ggtccgcggg gccggttcgc ccgccgaact cgccccctac gtcgcctggg tggactccgt
    11041 gaccgccgga ctcacccgcg cgctggccgc ggtgcacgcg cgggggctgc gcttcggcga
    11101 cctgcacccg tccaacgtca tcgtccggcc cgacggcggt gtggtgctca tcgacttcga
    11161 gtacgccacc gccctcgacg accaggacac gccgccggcg ggcgcaccgg gtctccaggc
    11221 accgcccggc acccccggtg ccgaggccga cgcctacgca ctgtgggcga cctggctcac
    11281 catgctgatg cccctcatgg agatggccgg gcacgaccgg gccaaggccg tgacgctcga
    11341 gcggtgggcc cgcacgcgct acggcctgac gccggacgcc ggcccgcacc gccccgccgc
    11401 cgtacgggcc gtgtccggcc cgcacagccg ggagcacgag atcgccgccc tcctcgacgg
    11461 ccccgcaccc gactggcggg aactccgcgc ccgcctgctg gcaggcatcc acgcgggggc
    11521 gacgcccgag cgccgtgacc gcctcttccc cggggacccg caggcgttcg ccaccggcgg
    11581 gaccgacctc gcgcacggcg cggccggggt gctgtacgcc ctgcaccggg tcggcgcccc
    11641 cgtcccggac gcctggacgg actggctcgc cgccgccgcc cgccgccgtg accccgcggc
    11701 tcccggaggg ctcttcgacg gactgcccgg cacggccgtg gtgctggcgg gtctgggccg
    11761 cccggccgac ggcagggaga tcctcgaacg ggccctggcc gccgcaccac cgaacacctc
    11821 ggccgatctg ttcaccggcc gcgcgggcgt cgcgctcgcc gcactgcggt tggcccgcac
    11881 gggcggctcc gcacccgacc ccgagctcct cgaatcggcc gtacgcaccg cgtggagcct
    11941 cgactgcctg gtccggggcg aaccggccgg cggtctgcgc gccccggact ccgccggact
    12001 gctgcgcggg ctgagcggag ccgcgctgct gcatctggag ctgcacgccc tgaccgggga
    12061 ggactggctc ctgaaggcgg cccgcacggc cctggagcgg gaggccgggc actgcgtcac
    12121 gatgcccgac ggaaccgtcc aggtgaagga cggacgccgc cacctgctct acctcgacca
    12181 gggcagtgga ggattcgccc tggtggcgca ggcgtacctg gcccggcacg aagcccccgg
    12241 cctggccgcc ctgctccccg gggtgcgcca gggctgcgtc ctcgaattcg tccgcgaacc
    12301 gggcctgttc accggacgcg ccggactcgt cgccaccgcc ggccagctgg gcgggcagga
    12361 ccgcacggac gcctcggtgc tggcctccgt gcgcaacctg tcctggcacc tgctcgccga
    12421 cggggaccgg ctgctggtcc ccggggcacg gctgcggcgc tgctccgccg acctggccac
    12481 cggcgcggcg ggcctgctgc tggccctgca cttcctgtcg ggcgccggga cggacgggcc
    12541 cggtgaacgg agcacatcag cgggcctgtt ggagctgctc accctcgggt gagcagcggg
    12601 tccgccgcgg ctcgccccgg ccggtccgcc gcggctcgcc ccggccggtc cgccgcggct
    12661 cgccccggcc ggtccgccgc cgctcacccc cggacgagcg acagatccga tccggttcgc
    12721 tcccgggcgt acagacagag caggcgcggc acctcgtaca gcgcggcgtg tgcggtgacc
    12781 tccccggccg gggaggtcac cgcaccggtg tcgaggagcg actcgacggt gcggatcgcc
    12841 gcccgctccc cgcagcccag cacgtccatc gcccggtcca gcgtgaagcc gccgtcgtgc
    12901 gcgaatccgg cgagccgggc cagcgcctcc cggttctgct ccgtgaggtc ctgccagccc
    12961 gaggcgatcc gcgaccgtac ggacacgtct ccggcgacga gctcgtccag cgccgccgac
    13021 gggtcgtcca gccgggacgc gtactccgcc agcggaaggt gccgcagcac cgccagccgc
    13081 atgccgctga ccgtcaccgc cagcggcagc gccccacagg cccgcacgat gcgcagggcc
    13141 gccgcggggt ccgtccggac ccggcccgcg ccgatcagcc tgcccagcag ctccagcgcc
    13201 tcaccgtcgg cgagcgcggt cagcgccacc cggtgcgccg gggccagtcc ggccagttga
    13261 ccgcgcgcgg tgaggagcac cgagcaccgc cccgaccggg gcagcagccc gcgcaccgag
    13321 gcctcgtcgg gcacgtcgtc caggacgatc agggcgcggt gccgtgacag ccagtcctgc
    13381 caggcgtcct cggcctccgg accgcccggc gggacccgcg ccccgcacag ccgccccagc
    13441 tcgcccagca cctcggcccg ggtgcgggcg gtgccgtcct cccgccgtac ccggacgtgg
    13501 acccgcccgt cggggaatcc gtccgcgagg agatgggccg cccgcacggc cagcgccgac
    13561 ttcccggacc cggcgggacc ggagacgatc agcaccccgc cctccgcggc ccccgactcg
    13621 tccagcacct cgcgcagttc gtctcggcgc ccggtgaagt cccgggccgc ggcgggcagg
    13681 gacaccccgc cggcgctgtc ccggggggtg gtggtgcgcg ccgcgcggcc ccggccgagc
    13741 atgtccgcgt agagggccgc catcgccggg ctgggttcca gccccagctc cctggcgagc
    13801 agctgccggt agtcgtcgta caccgccagc gcctccgcct gccgccccga ctggtgcagg
    13861 gagttcatcc aggccgcccg gagccgctcg cgcagcgggt ggcgctccac caggtcccgc
    13921 aggccgtcca ccgcgacggc cgcacggccg gtctcgatct cggcctcggc ccagtcctcg
    13981 tagaccgtca gacagcgtga ctccaggcgc tcggcctcct ccgccacccc ggcggagtcc
    14041 cggaggtcgt gcagcggctg ccgctccccc cacaggtcga gtgcctcccg cagcagccgt
    14101 gcggccgtgc gcaggtcccc ccgctcgccc gcggcccggc ccgagcgggc cagggcaccg
    14161 aagcgcaggg tgtccagctc ggcctcgccg atccgcagcc ggtagccgcc gcagccgtgc
    14221 accacccggt cccggtcgcc cgcggcgccg aacagggtcc gggccgcgct gatgtagacc
    14281 tgcagattct tgcgcgcggt ccggggcggt gcgtccggcc acaccacgtc ggtcagcacg
    14341 tccaccggca cgggggtgtt ggggcgggac agcagtgtgg cgaggacgag gcgctgcttg
    14401 cgcgggccga gcggcagcgg cctgccgtcc accacggcgg tgagcggacc gaggagggag
    14461 aagtacacgg caccggtggg accggggcgg gcgggggagc gggtcatcag cgggcctcct
    14521 ggggcgggga cgggcgacag gctgccgtac acccgccgat ccttccgtcc cgccggccgg
    14581 gacacatcgg tgctccgccc gcatcttccg gagccgcacc cgacccaaaa cggcccgtgc
    14641 ccccatgttg agcggtgctg cccccatccg ggcggatgtt gagcggtgcc gcccccatcc
    14701 gggcggacgg caccccgcag gcgaggtgcc ctcaggcgtg ctcgacggtg tgctcggcgg
    14761 cgtactcggc ggcgtactcg cacagggcgg cccggttctc ccgtccggtc ttgctgagca
    14821 gactggccat gtgcttctcc accgtgcggg gcgagatgga cagccgccgg gcgatctgct
    14881 ggttgcccgg ccgctcggcc agcagcacga acacctcgta ctcgcgcggt gtcaccccgg
    14941 tggtgcgcag cgacgaaggg atccggtccc ggccgccgcg gtgctgggtg acgctcgccc
    15001 ccgcctgccg cagggcggcc cggcacgcgg cggccaccgg ctgcaccccc gccccgtaga
    15061 agaactcctc ggcggtgcgc agccaggcca ccggttcgcc ccacccgtcg gcgcgggcgg
    15121 cgtccgcgac cagccgcagg ccgaggtggc gggccaccgg gaacgccgcc gacctggcct
    15181 cgaaggcggc catcagccgg gcggcacccg cacggtcgcc gtcccggccc agcagcaccg
    15241 cctccgccag gtccatgaac tgcctgttcc aggccaggcc ggcaccgggc gaggccgtca
    15301 cggcgtcgta ctcccgccgg tccgcctctc ccgccaggat ccgcagcagc ggccgcagcc
    15361 cgtagcggcc gctcaggtag aagtagctgg gatggtcgcg ctcccacccc agggcggcgt
    15421 ccaggtcgga cagggcgcgg ccccggtcct cgtcgagcag cgcgccgatc gcacggcaga
    15481 gccccagccc cagcggtacg agcagggact gctcgccgcc ggcccggcgg aacgcggcga
    15541 gggagcggtc catctcgcgc cggcggccgc ggtgcgcggc catcgtcgcc ccggccagca
    15601 gcagatagcg gtgcgcggac agattgccga cccgggcgct cgcctccgcc gagcggtcga
    15661 tgatctcctg agcctcgtcc caccgggcgc acatcaccgc gttcatcgcg aggagtccgt
    15721 cgaccgtccg ggtcagcagc agtgcgccca gctccgtggc cgccgcccgc gcggagtgca
    15781 accgggccgc gtcaccggtc cgcatgaagc cgttcgcacc cagccgcacc atcgcctcca
    15841 cccgccacag gggcagggag tgctcggtgg acagggtgag catccgctcc aggcacgcgt
    15901 cggccgcgtc gaaccccttc tcgcgggaga gcagcgccag caactgccag gcctggcagg
    15961 cgaccacggg cagaccctcc gcctcggcgg tctccgccgc caggagcgcg gcccgctcgg
    16021 tctccccggg ctccccgcgg tcctcaccgg ggagcagcga cagatggccg tcgacgacga
    16081 cgagggccgc gcgccgggcc ggggacggcg aggggcccag cagaccgtgc gccgcgctga
    16141 tctggcgcgc cgcgtcggag acccgctccg ccatgaccgc cacccaggcg atcttgatgt
    16201 gtgcgtcgcc ccgccgggcg gcggcctcgg aacgcgccgg tacggggggc agggtgtccg
    16261 tcagcgccag ggcgccgtcc agatccccgc tctccgcacg ggccaccgcg aggtcctcgg
    16321 cgatggcggc ccggtcggac tcggcggcca gggagtgcgc ccgctccagc agcaccacgg
    16381 ccgagccgtg ggttcccgaa gcgagcaacc gtctcccggc ctcggcgaac tggagggccg
    16441 ctcccgagcg gttgcccgcc gccagttcca gggtcgcgac gagctgccgt cggtcctcgt
    16501 ccagcggctg accggagtgt tcgacggtcg cggcggcgcg gcgggcgagc gcggcgcgtt
    16561 cggcgggagc gagcgaggag accagggcct ccgcggtgag cgcgtgccgg aaggtgtagc
    16621 ggtcgggggc cgccccgtcc ggggcgatca cacccgcttc gacggcggac ctcaggtgcg
    16681 tgaacaaggc gcggtcctcg aaaccggtga cggtctggag cacggtcacc gagaactggc
    16741 tgcccagggt ggccgccgtc aggagcaggt cccgcaccgg ttcgtccagc ctgtcgagcc
    16801 tgcgggtcca gctgcggagt atccccgacg ggagggcgca gtccggctgc tccgccgcgt
    16861 cccagccggc gtccgtcctg cgtaactgac cggtgtcgag caggtcggcc agcagcagct
    16921 ccacgaggta cgggttgcct gcggcgcgtt cggccagccg gtgctggacc acgggcggta
    16981 tgcgctcggg cggggtctcc agacaggcac cggtcagcag ccgcacctcg tcgtcgccga
    17041 gtgcccgcag ctcccgcacc gccgccgtct gacgccgctc ggcggagcgt acgaggtcca
    17101 gtgcggcccc cgcctccggc cgcagggtgc ccagcagcag gatgggcagg ccggccagat
    17161 tgtcgatgac gtactcgacg accgcgacgg tctccgtgtc ggagtcgtgc aggtcctcca
    17221 gcaggatcac gcagcccgtg tccctgccca ggacggacag cagccgcagc agcgcctccg
    17281 ccagctcgac caccgtctcc gggtagcccg gtgacgctcc gcgccgccac tccggcacca
    17341 gtctggccag cgccggatgg tacgggacca gctccggatc ggtcggtgtc ccggccgccc
    17401 ggaagtggga cgagagcgcc tccaccagcg ggcggtacgg cacgacgagg ccggtcgagc
    17461 tggcccggcc gcgcagcacc ggcatgccca gctcgtaggc ccggtaggcg cattcgccca
    17521 ccagccgtga cttgccgatc cccgcttcac cgaggaggaa cagcgcgcgc cccgaacgcc
    17581 gttgcacggc gtccagggcg ctgctcagca gtccgatctc accgtctcgt ccgacggtga
    17641 ccggcgaagt ggctcgcatg gccgcaggct acttgagcca cgacgcatac ggcagtaggc
    17701 cgcattcggt cgattacggt gcgatatcgg gcgatgtggt cacaacgggt tcgtcatggt
    17761 cgtgaacggc aggtcatggc tgtagccgat gtcgccctcc gaaacactca ggagccggct
    17821 gcgcaggccc agtgcgccac cggaggaacc aagggatatc cggcccgccg ggtgctcggg
    17881 ggcgccctcg tgcgccgtga cggctgcctg catggccgat tcgctgatct gcgtcatcat
    17941 ctctgcctca tctgactggt cgacaacgga gctggaaaag aggaccggtt cgtccccgtg
    18001 gtgccccccg tggagggctg tacgagcagt gccgagccga tccggtcggg aaaacccgcc
    18061 cgcaacaacc cgtgtcctat tcctgaaagg ccggtgagca gcccggggtg aggtacgttg
    18121 ccgggcgttc cgcactgcgg acccgcacgg tcggcggcgg ccaggagcgt tccggtccgg
    18181 cgcacccagg gggcgcggag gcccggcagg gcaccgtgac cgaggagttc cagcacaccc
    18241 agctcgccgt ggcagaggct gtcgttggcg ggcgggacgg cctccgccag tgcgccggcc
    18301 cggccggaca gccagccgga cagctccgga tcggccagcg cgtcggggct gtcggcgacc
    18361 gcgagcgcga cccccgtcgc gccgtcgcac caggcctgcc cggcgcccgc gccggagacc
    18421 gcccggcgca acgcccgcag cccggcggcg cggtagcggg gcccgcccnn nnnnnnnnnc
    18481 cggctgcggc gaagcgcaac agcgcccagc cgacgcccgc ggccccgtcg gcgaaaccgc
    18541 cggcctccgg gaggggcgcc gcggcgatcc gctccgcgca ccgctcggcg ccccgccagg
    18601 cctccggcct gccggtggcc cggtgcaccg cgagcagcga caccagcccg cccgccgcgc
    18661 cgccgcgcac cccgaagccg tcctccgccg aacccgccgc ggagctcagc cgggtggccg
    18721 ggcccgccca gtccagcacc tggtgatcgt ccagcaggaa acccacctcg gtcagcgtgt
    18781 acnnnnnnnn ngcgatgccg ccgagaccgg cgaaggcacc ggagccgagc agtccgaggt
    18841 cgtccacccg ttcgtggagg gcgtccagca gcccggggac gggagccagc gcctcgcggg
    18901 ccgcatcggc gtaccgggcg gccccggtca gggaggccag ctgggccagg aagagcgccg
    18961 gtcccgtgta gccgcccgcg aggtccgccg ccatgggcgt gagccgccag tagcgctcgc
    19021 cgagcagctc caggccgatc cagttggtgc ggccctcgtg gcggaaggcg agcgagacga
    19081 gctggtcgcc gaccgaccgc gcgacggaga gcaggtgctc cggttccggt gcggtgtcca
    19141 cggccggcgg ccggtgtccc gagcccgccc ggtgcgcggg ctcgggggag gtgctgacca
    19201 tggcggcgcg gatgatgtgt tcctggtcca gccggcccac cgtgtccagg gcgcgcacct
    19261 tggcctcgac ccgcaccagc ccggtcaccc cctcgggacc cgggacccgg cgaccggtgc
    19321 cgctccacag gtccgtggaa tcgggccggc cggcgaacac cggtacgtcc ccgttccaca
    19381 gctccgtgat ctcctcgtcc tccaggccgg gcagtgcggt ggtgcccagg gacggggtcc
    19441 gcagcagtgc gaagatccgg tgccgttcgg tggcgtcccg catcaggtcg gggtgggtgg
    19501 actcgtccag cagggtggtg tacgtccagg tcggccgggg tacgacgcgg atctcgtcct
    19561 gggcgaagag gcgcaacagc cccttcggcc ccaggagttc gtcccgggcg tcgccgactg
    19621 ccgtgtagcc cgcgcggaat ccgtcgcaca gggcgtccgt gtaggaggag gggtcggccg
    19681 ggatcccgcc cagccggggc cggttggccg actcggtgaa ccggcccgcc gtccggacca
    19741 ggcgcatccg gtccgtcccc gccgcatccc agcccgccgt ctcgatgggg gaggagcctg
    19801 ccccgccgcc gccgatggcc gacatgtcga gcgccgtcgt gtccccgacg agcagctggg
    19861 gcagcagccc cacgcggtgg accgaggcgt gcagggcccg cgccgccgga tccgcggagc
    19921 gggccggtac cagcggcgga tggaacagcg tctccacgtc gacgaggacg gggtgcgggc
    19981 cgcaggcgat caggttctcg tggtgcagat cggtcccgtc cagcacgtgc agcagcgcca
    20041 gcagcgcacc ctggcgccgg tagaagcggg tggtctccgc cgccgagtcg cagggccgct
    20101 cctcgacgaa ctcgacccag ccgtacgcac cccggtccag gacacgcggt gtgcgcagat
    20161 cgggcgtcgc gggcagcgag ttgaaccatt cgaccagggt gttgaagtgc tggtgggcgg
    20221 cgagcggacg cggcttgtac accagccggg tgccgtcggc gaaccgcagc agcatcaccg
    20281 accggccccc gcggtgactg tcacccgcac cggcctcgac cccggtcagc cctccgggcc
    20341 cccggtcgcc gaggaccccg gcaccccggt caccgagcag cccggaggcc tgcagcagct
    20401 cccggtcggc cgcgagcctc ccgaacatct ccgcgaagga gtcggccgcg ttcatgctcg
    20461 tccgtgccac gatccgggcc agcacgggat aaccggtgac gagcgaggcg agaccggacc
    20521 ggcgtgcggt cagccggagg aagtcccgga accgctcccg cgtcccgtcc ccgccgagcc
    20581 gcccctcctg ccgcgcttcg tgcagttcca gcaccagcgt ccgggccgcg agacgggcca
    20641 gacggcctgt cagatggctc cggaagtcgt ccagcacggc ggcgggacag gcgacgggcc
    20701 cggctcccgg gacgtcgtcc ggggcggacg ggcggtcggc ggcccggccc catgcctggt
    20761 ccgcggcctg ctccaccgcc cggtcgacgg cccgctccgc gaacggtgcc atgatcagcg
    20821 cgaagcccga cagtccgggg tactcccggt cggcggccac cgcgtcgcgc ggtgcgcccg
    20881 ccacgacgtc ccggacgaag accgcccagt ccggctcggc ggcgggccgc tgtccgacga
    20941 caccggggag ccaccacgga tcgccctggc cccgggcgcc caggagggcg gtgtccggtg
    21001 cgtgggcgtg ctccggaccg gcggtgcccg cacggccggc gggtacgtcc ttcaggggcg
    21061 cgtcgggaac gccgcggcgc gtgtcggggg cggcggaggc cgggatctcg cggggcgagg
    21121 cccccgggac atcgcgggtg gaggcgctca ggttcgctct gccgttcgga tccttctccg
    21181 ccaccgcgca cacctccctg gcccggggag gcctaccggt cctcccgcac cccatcctgg
    21241 tgggcgggag gggccgggcg catgggggag tcgcccccat ctttcgggtg ccggcgcacg
    21301 aggccgcgtg ggtgcggggg acggagatga gggttccgga gtgctggtaa agacggtccg
    21361 gggcgccgga ggtgacgttc ccggggcgcc cggctcaccc ccgtggcggc gccgtcgacc
    21421 cccgcaccat cagttccgcc tcgatcgtcg cgatgccccc cggcggcggc gtctccttgc
    21481 ccatggccag ccgccccgcc cgcgcccccg cctcgaacag cggcagccgt acggtcgtca
    21541 gggccggcac cgcgtccacc gagaacggca ggtcgtcgaa gcccgccacc gagacgtcct
    21601 ccgggatgcg gagcccgtgc tccctgatcg ccgcgccggc ccccagggcg acggtgtcgt
    21661 tcgcggcgac gaccgccgtc acctccggtg cgcggcgcag gagttcgagc gtcgcgtcgt
    21721 atcccgaccg ccggtcgtac gggccgtgca cggtgaggct ctcctcgtcc gcgtacaggc
    21781 ccgccgcctt catcgcctcg cggtggccct ccaggcggtg ccgggtcgtg gtgcgttcca
    21841 gcggccccgc gacatagccg atccgccggt ggccgagctc cagcaggtgc tcggtgagcc
    21901 gccggccgcc gccccggttg tcgaaggcca gcgcggccac gaccgcgtcc gagtccggca
    21961 gcggggggcg cccgcagaag acgatccggg tgcccgcgtc cgcgagcttc gccagcttcg
    22021 cggccatgac ggcctggtga gccgggtcct cgagggcgcc gccggtgagg acgacggccg
    22081 cggcgcgctg gcgctggagc agggtgagat aggtgagctc gcgctcgggg gagccccccg
    22141 tgttgcacac gacggcgagc ttctcgccgc ccgcacggcc cgacccgtcc ccgggaccgc
    22201 cgatctcgct ctgcgcggcc cccgccatga tcccgaagaa cgggtcggcg atgtcgttca
    22261 cgaggatccc gacgaggtcg gacgtggcgg cggcgaggga gctggccggc ccgttcagca
    22321 cgtagtccag atcgtccacc gcacgcagga cccggtcccg ggtggacgcg gccaccggat
    22381 agttgccgtt cagcacgcgg gagacggtgg ccggggacac ccgggcgcgg gccgccacgt
    22441 ccgccagggt gactgtcatc gttctccttc gaggagttgt ggcgcggccc cccttgtccg
    22501 ggccgctgtc ggcaggctag cgtcataccg catagaaagc gcttgctacg gctgtatgga
    22561 gggaactttc gtgacacgca ggacagtgcg ca
//
