LOCUS       NZ_LMEU01000006        18574 bp    DNA     linear   CON 26-MAY-2024
DEFINITION  Streptomyces sp. Root1319 contig_14, whole genome shotgun sequence.
ACCESSION   NZ_LMEU01000006
VERSION     NZ_LMEU01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root1319
  ORGANISM  Streptomyces sp. Root1319
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 334220)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 334220)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140604
            Assembly Name                     :: Root1319
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001426615.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 02:19:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,915
            CDSs (total)                      :: 5,857
            Genes (coding)                    :: 5,667
            CDSs (with protein)               :: 5,667
            Genes (RNA)                       :: 58
            rRNAs                             :: 2, 1 (16S, 23S)
            partial rRNAs                     :: 2, 1 (16S, 23S)
            tRNAs                             :: 52
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 190
            CDSs (without protein)            :: 190
            Pseudo Genes (ambiguous residues) :: 0 of 190
            Pseudo Genes (frameshifted)       :: 64 of 190
            Pseudo Genes (incomplete)         :: 160 of 190
            Pseudo Genes (internal stop)      :: 8 of 190
            Pseudo Genes (multiple problems)  :: 38 of 190
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:44:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 18574
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMEU01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..18574
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..18574
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..18574
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[2036:8574](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(2037..8574)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     CDS             complement(<1..194)
                     /EC_number="1.17.7.3"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=2
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018534474.1"
                     /locus_tag="ASD26_RS28845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_199862698.1"
                     /transl_table=11
                     /translation="MCQIVRVACPTQDDADALSTIARKSQIPVIADIHFQPKYVFAAID
                     AGCAAVRVNPGNIKQFDDKV"
     gene            complement(<1..>196)
                     /locus_tag="ASD26_RS28845"
     assembly_gap    197..267
                     /estimated_length=71
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(353..1372)
                     /gene="hpnH"
                     /locus_tag="ASD26_RS02325"
                     /old_locus_tag="ASD26_20450"
     CDS             complement(353..1372)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128938.1"
                     /locus_tag="ASD26_RS02325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20450"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_056792476.1"
                     /sec_met_domain="PF04055 (E-value: 3e-18, bitscore: 61.0,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 5.8e-10, bitscore: 33.2,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLIEQKLRKRDKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKKKYVF
                     LCTNAMLMRKKLEKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAMKEAKRRGF
                     RVTTNSTFFNTDTPQTIIEVLNYLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKSFAGGNRARWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEETDWEKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARETIGGNR"
     gene            complement(1379..2032)
                     /locus_tag="ASD26_RS02330"
                     /old_locus_tag="ASD26_20455"
     CDS             complement(1379..2032)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964847.1"
                     /locus_tag="ASD26_RS02330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20455"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_056792475.1"
                     /transl_table=11
                     /translation="MGDARRHPAPVMPLLIACALGIEHLALRTGRGKGGPGPVTVIRTG
                     MGPKAAENAVRRALGQDGVRGAAVIASGFCAGLAPGMHPGDLVVAEETRDDSGTTACTG
                     TGLLVDALTRAVPGRNVHTGPVTGSGHVVRGAERAGLRATGAIAVDMESAATLRTAVRT
                     GPRPVAAVRVVVDAPEYELVRIGTVRGGISAFRVLRAVLPAFHEWHRSLLLPRR"
     gene            complement(2037..4031)
                     /gene="shc"
                     /locus_tag="ASD26_RS02335"
                     /old_locus_tag="ASD26_20460"
     CDS             complement(2037..4031)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152781.1"
                     /locus_tag="ASD26_RS02335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20460"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_056792474.1"
                     /sec_met_domain="T2TS (E-value: 9.9e-149, bitscore: 490.5,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGAANLRAAPVSDPTDTTTAADDVLAAARQAAERSVR
                     HLLGRQDEQGWWKGDLATNVTMDAEDLLLRQFLGIQDPATVKAAARFIRGEQLGDGTWA
                     TFHGGPGDLSATIEGYVALRLAGDRPDDPHMIRAARFVRDRGGIAAARVFTRIWLALFG
                     WWKWDDLPELPPELMFFPKWVPLNIYDFGCWARQTIVPLTVVSAKRPVRPAPFTLDELH
                     TDPARPNPPGRTAPVASWDGVFQRLDKALHLYHKVAPRGLRRIAMNAAARWIIERQEND
                     GCWGGIQPPAVYSVIALHLLGYDLDHPVMRAGLASLDRFTVLREDGARMVEACQSPVWD
                     TCLATIALADAGLSPDHPALVKAADWMLGEEIVRPGDWSVRKPRLAPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVRHPDPERVEAAIDRGVRWNLGMQSRNGAWGAFDADNTSPFPNR
                     LPFCDFGEVIDPPSADVTGHVVEMLAVEGRSSHPRTRRGIEWLLAEQEASGAWFGRWGV
                     NYIYGTGSVVPALIAAGLPAAHPSVRRAVGWLESVQNEDGGWGEDLRSYQQEEWVGRGA
                     STASQTAWALLALLAAGERDGRPVARGIGWLAGTQQADGSWDEPYFTGTGFPWDFSINY
                     HLYRQVFPLTALGRYVYGDPFATGTGKGA"
     misc_feature    complement(4112..4128)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 22.51"
                     /tool="antismash"
     misc_feature    4122..4137
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.8"
                     /tool="antismash"
     misc_feature    complement(4125..4140)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.18"
                     /tool="antismash"
     gene            complement(4136..5239)
                     /locus_tag="ASD26_RS02340"
                     /old_locus_tag="ASD26_20465"
     CDS             complement(4136..5239)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964849.1"
                     /locus_tag="ASD26_RS02340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20465"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_056792473.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.9e-61, bitscore:
                     201.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTTGTRGESVTPANPAYDTVADTTDVTALLERGRALSTPVLRA
                     AVDRLAPPMDTVAAYHFGWIDAQGRPADGDGGKAVRPALALLSAEAAGAPPEAGIPGAV
                     AVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALANEILLELGTVE
                     AGRAARRLTTATRKLIDGQAQDISYEHRERVTVEECLEMEGNKTGALLACAVSIGAVLG
                     GADDRTADTLEAYGYHLGLAFQAVDDLLGIWGDPESTGKQTWSDLRQRKKSLPVVAALA
                     AGGPASAQLGELLAADAKSNDFDSFSEEEFAARAALIEEAGGREWTAQEARRQHAVAIE
                     ALHGVDMPEQVRAQLTALADFVVVRKR"
     gene            complement(5236..6624)
                     /gene="hpnE"
                     /locus_tag="ASD26_RS02345"
                     /old_locus_tag="ASD26_20470"
     CDS             complement(5236..6624)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579669.1"
                     /locus_tag="ASD26_RS02345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20470"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_056792472.1"
                     /sec_met_domain="DAO (E-value: 1.7e-10, bitscore: 35.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGQDPRSSRAVVVGGGLAGVTAALRLADAGLDVTLLEGRPRLGG
                     LAFSFRRGELSVDNGQHVFLRCCTAYRWFLDRIEGTHLAPLQERLDVPVLDVGRARGPR
                     LGRLRRTGLPVPLHLAGGLAAYPHLTLAEKAGVARAALALGRLDPADPALDGIDFATWL
                     RRNGQSQRTVEALWDLVGVATLNATAPDASMALAAMVFKTGLLSEPGAADIGWAAVPLG
                     ELHDTLARKALESAGVRLHVRTRAGSLTRTEDGRWAVGTDGSRFEADTVVLAVPQGETH
                     GLLPDGAIDDPGRLLELTDAPILNVHVVYDRKVLRRPFFAALGSPVQWVFDRTATSGLR
                     GGGQYLAVSQSAAQDEIDLPVAELRRRYLPELEKLLPAARGAGVRDFFVTRERTATFAP
                     APGTGRLRPGAHTRAPGLHLAGAWTATGWPATMEGAVRSGFSAADAALHTLGRPHEHPL
                     QEAA"
     gene            complement(6710..7630)
                     /gene="hpnD"
                     /locus_tag="ASD26_RS02350"
                     /old_locus_tag="ASD26_20475"
     CDS             complement(6710..7630)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018492033.1"
                     /locus_tag="ASD26_RS02350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20475"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_199862702.1"
                     /sec_met_domain="phytoene_synt (E-value: 8.3e-59, bitscore:
                     193.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 2.8e-71,
                     bitscore: 234.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPVQAAYSYCEAVTGQQARNFAYGIRLLPYEKRQAMSALYAFS
                     RRVDDIGDGELAPETKRTRLEDTRELLGRIRDGAVDEDDTDPVAVALADAARRFPLPLG
                     GLDELIDGVLMDVRGASYETWDDLRTYCRCVAGAIGRLSLGVFGTEPGAPGADRAAEYA
                     DTLGLALQLTNILRDVREDAGNGRTYLPADDLAKFGCSAGFHRATPPPGSDFAGLVHFE
                     VRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLRGRVSLPGHEK
                     AYVAVRGLSGLDARYISRRTTRGRA"
     gene            complement(7660..8574)
                     /gene="hpnC"
                     /locus_tag="ASD26_RS02355"
                     /old_locus_tag="ASD26_20480"
     CDS             complement(7660..8574)
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552438.1"
                     /locus_tag="ASD26_RS02355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20480"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_056792471.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.9e-38, bitscore:
                     125.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 8.8e-40,
                     bitscore: 131.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTQQARTDATSTLDKAADENFPVAPFFLPRAWRDDLMAVYGFA
                     RLVDDIGDGDLAPGGADARHLGVGPGTAEDRLALLDALEADLHRVFADAAGGPLHPLMR
                     ALLPTVRRCALTPDPFLGLIEANRQDQKVRRYGTYEELLAYCELSANPVGRLVLQITGT
                     ASPERIRRSDAVCTALQIAEHLQDVTEDLGRDRIYLPAEDMARFHVSESDLAAPTGGAS
                     LRALVAFEAQRAHDLLDEGIPLVGSVRGRLRLLLAGFVGGGRAALTAVAAAGFDVLPGP
                     PKPTAPRLLREVGVVLRKAYREG"
     misc_feature    8705..8723
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 21.52"
                     /tool="antismash"
     misc_feature    complement(8839..8852)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 20.8"
                     /tool="antismash"
     gene            complement(8990..9775)
                     /locus_tag="ASD26_RS02360"
                     /old_locus_tag="ASD26_20485"
     CDS             complement(8990..9775)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964853.1"
                     /locus_tag="ASD26_RS02360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20485"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_056792470.1"
                     /transl_table=11
                     /translation="MAEESSQGHIPTVIADDVHIVYRVNGTGGGKGSATAALSRIMRRG
                     KGEPRGVRKVHAVRGVSFTAYRGQAIGLIGTNGSGKSTLLRAIAGLLPTEHGKVYTDGQ
                     PSLLGVNAALMSDLTGERNVVLGGLAMGMSREEIRSRYQDIVDFSGINEKGDFITLPMR
                     TYSSGMAARLRFSIAAAKNHDVLMIDEALATGDRKFRVRSEARIRELRKEAGTVFLVSH
                     NNKTIRDTCDRVLWLERGELLMDGPTEEVLKAYERETGK"
     gene            complement(9768..10697)
                     /locus_tag="ASD26_RS02365"
                     /old_locus_tag="ASD26_20490"
     CDS             complement(9768..10697)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="ASD26_RS02365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20490"
                     /product="ABC transporter permease"
                     /protein_id="WP_056792469.1"
                     /transl_table=11
                     /translation="MSDTTHDGGIALSSPPSADEGLSASGLAAKYGLTVSGARPGLFAY
                     VRQLWGRRHFILAFSRAKLTAQYSQAKLGQLWQVATPLLNALVYFLIFGIILGTSRGMS
                     QEVFVPFLVTGVFVFTFTQSSVMAGVRSIAGNLGLVRALHFPRASLPVSFSLQQLQQLL
                     YSMIVLFAVAIAFGSYPTLSWLLIVPALAMQFLFNTGLALVMARLGSKTPDLAQLMPFV
                     MRTWMYASGVMFSIPVMLADKPQWIADVLQYNPAAVYMDLVRFALIDGYGSENLPQHVW
                     AVGLAWSLLVGVLGFVYFWKAEERYGRG"
     gene            complement(10806..11690)
                     /locus_tag="ASD26_RS02370"
                     /old_locus_tag="ASD26_20495"
     CDS             complement(10806..11690)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983096.1"
                     /locus_tag="ASD26_RS02370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20495"
                     /product="glycosyltransferase"
                     /protein_id="WP_056792468.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-12,
                     bitscore: 42.3, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPMKIGAVIITMGNRPDELRALLDSVAGQNGDRIEVVVVGNGA
                     PVPDVPAGVRTVELPENLGIPGGRNVGIEAFGASGTDVDVLLFLDDDGLLAKNDTAELC
                     RQAFAADPELGIITFRIADPETGVTQRRHVPRLRAADPMRSSRVTTFLGGANAVRTRVI
                     AEVGPLPDDFFYAHEETDLAWRALDAGWMIDYRADMVLNHPTTAPSRHAVYHRMVARNR
                     VWLARRNLPAPLVPVYVGVWLLLTLVRKPSLPALRAWFGGFREGWTKPCGPRRPMRWRT
                     VWRLTRLGRPPVI"
     gene            complement(11687..12466)
                     /locus_tag="ASD26_RS02375"
                     /old_locus_tag="ASD26_20500"
     CDS             complement(11687..12466)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="ASD26_RS02375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20500"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_079099267.1"
                     /transl_table=11
                     /translation="MQKPSIAELRPVVHPPGVKDRRSGEHWAGRLYMREISLRITRRLV
                     TTKVTPNQLTYVMTVAGVLAAPALLVPGIPGALLGVVAVQLYLLFDCVDGEVARWKKQY
                     SLGGVYLDRVAAYLCDAAVLVGFGLRAADLWGPGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQGGLPPVKESASEPRSSGMALARRAAGALKFHRLILGIEASLVILVVAVLDT
                     VRDDFFFSRLAVAVMAGIALLQTVLHLVSILASSRLK"
     gene            complement(12444..13505)
                     /locus_tag="ASD26_RS02380"
                     /old_locus_tag="ASD26_20505"
     CDS             complement(12444..13505)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="ASD26_RS02380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20505"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_056792466.1"
                     /sec_met_domain="Fe-ADH (E-value: 8.3e-18, bitscore: 58.5,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 2e-08, bitscore:
                     27.9, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRRGAMDDLAGLLADQRISASGKLAIAISG
                     GSGLALRERLAPVLPGADWYPVGDGTIDSAVRLADGIKGNRYDALVGLGGGKIIDVAKY
                     AAARVGMPMVAVATNLSHDGLCSPVATLDNDNGRGSYGVPTPIAVVIDLDVIREAPARY
                     VRSGIGDAVSNISCVADWELAHEIQGEEIDGLAAAMARQAGEAVLRHPGGVGDDAFLKV
                     LAEGLVLTGISMSVAGDSRPASGGCHEINHAFDLLYPKRAASHGEQVGLGACFAMHLRG
                     AREESLHMASVLRRHGLPVLPGEIGFTPDEFVRAVEYAPQTRPGRFTILEHLNLSTDQI
                     RDAYADYAKAIHS"
     gene            complement(13493..14230)
                     /locus_tag="ASD26_RS02385"
                     /old_locus_tag="ASD26_20510"
     CDS             complement(13493..14230)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955403.1"
                     /locus_tag="ASD26_RS02385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20510"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_056792465.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.9e-13, bitscore:
                     45.3, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGEKTVLDLTLANFAEV
                     GLTEVAIVVGYRKEAVYARKAEFEATYGVKLTLIDNDKAEEWNNAYSLWCAREVLKQGV
                     ILANGDTVHPVSVERTLLDARGKGQKIILALDTVKNLADEEMKVITEGDQGVRRITKLM
                     DPATATGEYIGVTLIEPEAAEELADALRTTFERDPDLYYEDGYQELVNRGFTVDVAPIG
                     EVTWVEIDNHDDLARGREIACLY"
     gene            complement(14227..16014)
                     /locus_tag="ASD26_RS02390"
                     /old_locus_tag="ASD26_20515"
     CDS             complement(14227..16014)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010058029.1"
                     /locus_tag="ASD26_RS02390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20515"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_056792464.1"
                     /transl_table=11
                     /translation="MRSLGFDVRAATDATEAAELLAAVPASQRVALVDPRFVGHVHALR
                     LGLTDPRFAVATVPGALTAQPEARAAVLGALRTAVAAVGAGVGTGSPVAPPGAEPAAED
                     HTVPGRLAAALDAEGTAVQRPELGSLTAAVPDGPEDRAAVRSAVAAVDDEAVRLRSAVK
                     AHDGFFTTFFISPYSRYIARWCARRGFTPNQVTTASLITALIAAGSAATGTRGGYVAAG
                     VLLLLSFVLDCTDGQLARYSLQYSTMGAWLDATFDRAKEYAYYAGLALGAARGGDDVWV
                     LALGAMVLQACRHVVDFSFNEANHDAVSNTSPTAALSDKLDSVGWTVWLRRMIVLPIGE
                     RWAMIAVLTAVTTPRIVFYALLVGCALAACYTTAGRLLRSLTRKAQRTDRAAGALADLA
                     DSGPLAQAVAAVVRRPGGGFTAPLLALAGALVLVAAALFAPYGSWLTVGAAGVYAVVSG
                     LAVSRPLKGALDWLVPPVFRAAEYCTVLVLAARSDVPHAVPAAFGLVSAVAYHHYDTVY
                     RIRGGTGAPPQWLVRTIGGHEGRTLVVAVLAALLTGASAFTTALTALAAAVALVVLVES
                     IRFWVSSSAPAVHDEGELA"
     misc_feature    16224..16239
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    16236..16250
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 20.76"
                     /tool="antismash"
     gene            16351..17334
                     /gene="galE"
                     /locus_tag="ASD26_RS02395"
                     /old_locus_tag="ASD26_20520"
     CDS             16351..17334
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (64-206). E-value:
                     2.5e-10. Score: 31.8. Matches aSDomain:
                     nrpspksdomains_ASD26_RS02395_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049647.1"
                     /locus_tag="ASD26_RS02395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20520"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_056792463.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.7e-18, bitscore:
                     60.9, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.8e-13,
                     bitscore: 44.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVARAMTGAGEKVVVLDDISTGIAGRLPADI
                     ELVRGSAHDRGLLDRVLAEHAITGVVHLAAKKQVGESVEKPLLYYRENVTGLAVLLEAV
                     VAAGVRQFLLSSSAAVYGVPDTDLIAEDTPCAPINPYGETKLVGEWMVRAAGRAHGIST
                     ACLRYFNVAGTDRPELSDTGVFNVVPMFFDRLTRGEAPRIFGDDYPTPDGTCVRDYIHV
                     ADLADAHLAVARKLAGQGAGEDLTVNIGRGEGVSVRQLADLVGEVTGRPVEPVVEARRP
                     GDAARAVASADRMTEELGWTARRGVREMVESAWEGWCLRHPEARAQ"
     CDS_motif       16354..16440
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD26_RS02395_0001"
                     /evalue="1.50E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ASD26_RS02395"
                     /protein_end="30"
                     /protein_start="1"
                     /score="17.6"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVARAMTGAGEKVVVL"
     aSDomain        16543..16968
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD26_RS02395_NAD_binding_4.1"
                     /evalue="2.50E-10"
                     /label="ASD26_RS02395_NAD_binding_4.1"
                     /locus_tag="ASD26_RS02395"
                     /protein_end="206"
                     /protein_start="64"
                     /score="31.8"
                     /tool="antismash"
                     /translation="HAITGVVHLAAKKQVGESVEKPLLYYRENVTGLAVLLEAVVAAGV
                     RQFLLSSSAAVYGVPDTDLIAEDTPCAPINPYGETKLVGEWMVRAAGRAHGISTACLRY
                     FNVAGTDRPELSDTGVFNVVPMFFDRLTRGEAPRIFGD"
     misc_feature    complement(17391..17405)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            17498..18439
                     /locus_tag="ASD26_RS02400"
                     /old_locus_tag="ASD26_20525"
     CDS             17498..18439
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049646.1"
                     /locus_tag="ASD26_RS02400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD26_20525"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_056792462.1"
                     /transl_table=11
                     /translation="MGAGHDHGHTHGGPPPTGTAAAAYKGRLRVALGITLGVMVMEIIG
                     GLLSDSLALIADAAHMATDALGLGMALLAIHFANRPAGPNRTFGFARAEILAALANCLL
                     LLGVGGYLVFEAVDRFITPAETQGGLAIAFAAVGLVANVVSLSLLMRGQKDSLNVRGAY
                     LEVVADTLGSVTVLVSAGIIMATGWQAADPIASLLIGLMIVPRTVKLLRETLNVLLESA
                     PKGVDMEEVRAHITALPGVLDVHDLHAWTITSGMPVLSAHVVVHQEMLDSIGHEKLLHD
                     LQGCLGVHFDVEHCTFQLEPSGHAEHEARLCH"
ORIGIN
        1 gaccttgtcg tcgaactgct tgatgttgcc cggattcacc cgcaccgccg cacaccccgc
       61 gtcgatcgcg gcgaacacgt acttcggctg gaaatgaatg tccgcgatca ccgggatctg
      121 cgacttccgc gcgatcgtcg acaacgcgtc cgcgtcgtcc tgcgtcggac acgccacccg
      181 cacgatctga cagcccnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
      241 nnnnnnnnnn nnnnnnnnnn nnnnnnngcg ccgtgagggg cggcgcaccg cgagcggccg
      301 ggccggcagc gcggggagac ccagcgcgac cggctctccc gcggtcatgg cgtcaccggt
      361 tcccgccgat ggtctcccgc gccgcccgca gggactcctt cagcgacccc atggtggcga
      421 ggacggcggt cggctcgtag ccgcagtgcg ccatgcagtt ggcgcaccgc gggtccttgc
      481 cgcgtccgta cttctcccag tcggtctcct cgatgagctc ccggtacgtg gggacgtacc
      541 cgtcgctcat caggtagcag ggacgctgcc atccgaagag cgagtagttg gggatcgccc
      601 aggccgtgca cgggaagtcc gccttgccct ccaggaagtc caggaagagc ggcgagtggt
      661 tcaggcgcca gcgggccctg ttcccgccgg cgaaggactt cttgaagagc tcgcgggtct
      721 gctccacgcc caggaagtgc tcctgatcgg gtgccttctc gtaggcgtac gcgggcgaga
      781 tcatcatctc gtcgaccttc aggtcgtcgt tgaggtagtt gaggacctcg atgatggtct
      841 ggggggtgtc ggtgttgaag aaggtggagt tggtggtgac ccggaagccg cgccgcttgg
      901 cctccttcat cgcctccacc gcctcgtcga agacaccttc cttggcgacg gactcgtcgt
      961 gccgctcgcg cagtccgtcg atgtgcacgg cgaaggcgaa gtacggcgac ggcgtgaact
     1021 tctcgagctt cttacgcatc agcatggcgt tggtgcagag gaagacgtac ttcttcttcg
     1081 ccaccagctg acgcacgatc tcgtcgatct gggggtgcat cagcggttcc ccaccggcga
     1141 tggacaccat cggggcgccc gattcgagca ccgccccgac cgcctgggcg accggcatgc
     1201 gctgcttgag caccccggcc gggtgctgga tcttcccaca gccctcacac gccagattgc
     1261 aggcgaacaa gggctccagc tcgacgatca gcgggaactt gtcccgcttg cggagcttct
     1321 gttcgatcag atacgtcgca accttgatgg actgacggag cggcatggcc atctgggctc
     1381 acctcctggg gagcagcaaa gatcggtgcc attcatggaa agccggaagg acagcacgaa
     1441 gaacacggaa tgccgatatt ccaccgcgga ccgtgccgat acggacgagc tcgtactcag
     1501 gagcgtccac gaccactcgt acggccgcaa ccgggcgggg gccggtccgt acagcggtgc
     1561 ggagcgtggc ggcggactcc atgtccaccg cgatggctcc ggtggcccgg agcccggcgc
     1621 gttcggcacc ccggacgacg tgaccggagc cggtcaccgg cccggtgtgg acgttgcggc
     1681 ccggtaccgc tctggtcagc gcgtcgacca gcagacccgt ccccgtacag gccgtcgtgc
     1741 cgctgtcgtc ccgggtctcc tcggccacca cgaggtcacc ggggtgcatg ccgggggcca
     1801 gccccgcgca gaagcccgag gcgatgaccg cggcgccccg gaccccgtcc tgtcccagcg
     1861 cccggcggac ggcgttctcc gcggccttgg gacccatccc ggttctgatg acggtcaccg
     1921 ggccggggcc gcccttcccc ctgcccgtgc gcagggcgag gtgctcgatg ccgagcgcgc
     1981 aggcgatgag cagtggcatg acgggggcgg ggtgcctccg ggcatcgccc atccggtcag
     2041 gcccccttgc cggtaccggt ggcgaacggg tcgccgtaga cgtaccggcc gagggcggtg
     2101 agggggaaca cctgccggta gaggtggtag ttgatggaga agtcccaggg gaagccggtc
     2161 ccggtgaagt agggctcgtc ccacgagccg tcggcctgct gggtccccgc cagccagccg
     2221 attcccctcg cgacgggcct gccgtcgcgc tccccggccg cgaggagtgc gaggagtgcc
     2281 caagcggtct gggaggcggt cgacgcaccg cgtccgaccc actcctcctg ctggtaggag
     2341 cgcaggtcct cgccccagcc gccgtcctcg ttctggacgg actccagcca tccgacggcc
     2401 cgccggacgg aggggtgcgc cgcgggcagc ccggccgcga tcagggccgg caccacggac
     2461 ccggtgccgt agatgtagtt gacgccccat ctgccgaacc acgcaccgct cgcctcctgt
     2521 tcggcgagca gccactcgat gccgcggcgg gtgcgggggt ggctcgaacg cccctcgacg
     2581 gcgagcatct ccaccacgtg cccggtgacg tcggcggacg gcggatcgat gacctcgccg
     2641 aagtcgcaga acggcagccg attggggaag gggctggtgt tgtccgcgtc gaaggcgccc
     2701 caggcgccgt tgcgggactg catgccgagg ttccagcgca ccccgcggtc gatcgcggcc
     2761 tcgaccctct cggggtcggg gtgacgcacc cggcgcagcg cgaggacgac ttccgcggtg
     2821 tcgtcgatgt cggggtagtt gtcgttgtgg aactcgaacg cccacccccc cggggccagt
     2881 cggggcttgc gcaccgacca gtcgcccggc cgtacgatct cctcgcccag catccagtcg
     2941 gcggccttca cgagggccgg gtggtcgggg ctcagcccgg cgtcggcgag cgcgatggtg
     3001 gcgaggcagg tgtcccagac cggtgactgg caggcttcga ccatacgggc gccgtcctcg
     3061 cgcaggacgg tgaaccggtc gagcgaggcg agtccggcgc gcatcaccgg gtggtcgagg
     3121 tcgtagccca gcaggtgcag ggcgatgacg gagtagacgg cgggcggctg gatcccgccc
     3181 cagcacccgt cgttctcctg gcgctcgatg atccagcggg ccgccgcgtt catggcgatg
     3241 cgccgcagtc cgcgcggggc gaccttgtgg tagaggtgca gtgccttgtc gagccgctgg
     3301 aagacgccgt cccagctggc caccggagcc gtacgcccgg gagggttcgg gcgggcgggg
     3361 tcggtgtgca gctcgtcgag ggtgaacggg gcggggcgga cgggccgctt cgcggagacg
     3421 acggtgagcg ggacgatggt ctgacgggcc cagcagccga agtcgtagat gttgagcggg
     3481 acccacttcg ggaagaacat gagctcgggc gggagctcgg gcaggtcgtc ccacttccac
     3541 cagccgaaga gcgcgagcca gatgcgggtg aagacccggg ctgccgcgat gcctccccgg
     3601 tcccggacga agcgggccgc acggatcatg tgcgggtcgt ccggccggtc tccggccagc
     3661 cggagcgcga cgtacccctc gatggtggcg gagaggtcgc cgggaccgcc gtggaaggtc
     3721 gcccaggttc cgtcgcccag ttgctcgccg cggatgaagc gggctgccgc cttcacggtg
     3781 gccgggtcct ggatgcccag gaactgacgg agcagcaggt cctcggcgtc catcgtgacg
     3841 ttggtggcga ggtccccctt ccaccagccc tgctcgtcct gcctgccgag gaggtgccgc
     3901 accgagcgtt ccgcggcctg ccgcgcggcg gcgagcacat cgtccgcggc agtggtcgtg
     3961 tcggtcggat cgcttaccgg ggctgcgcgg aggttcgcgg ctccggtgct tccgtcggtc
     4021 gtcgctgtca tggcttcccc ttcgtgcagt tggtccgctg ctgtgctggg gtctccgtcg
     4081 gcgggtgccc ggtcagggca cccgccggcg actgcgagtc atatgcgaat ggtgatcatc
     4141 tctttcgtac gacgacgaag tcggcaagtg cggtgagctg tgcccgtacc tgttccggca
     4201 tgtcgacgcc gtgcagtgcc tcgatggcca cggcgtgctg acgacgggct tcctgggcgg
     4261 tccactcccg gccgcccgcc tcctcgatga gtgccgcgcg tgcggcgaac tcctcctcgg
     4321 agaagctgtc gaagtcgttg ctcttggcgt cggcggccag cagctcgccc agctgggcgg
     4381 aggccggtcc gcccgcggcg agcgcggcga cgacgggcag ggacttcttg cgctggcgca
     4441 gatcactcca ggtctgcttg cccgtggact ccgggtctcc ccagatcccg agcaggtcgt
     4501 cgacggcctg gaaggcgagg ccgaggtggt agccgtacgc ctccagtgtg tcggcggtgc
     4561 ggtcgtcggc gccgccgagc accgctccga tggacacggc gcaggcgagc agcgcgcccg
     4621 tcttgttgcc ctccatctcc aggcactcct cgacggtgac ccgctcgcgg tgctcgtagg
     4681 agatgtcctg ggcctgcccg tcgatgagct tgcgggtggc ggtggtcagc cggcgggccg
     4741 cccggccggc ctcgacggtg ccgagctcca gcaggatctc gttggccagc gcgaagagcg
     4801 cgtcgccgac gaggatggcc tgggccggcc cgtgcacctt ccacacggtg tcccggtggc
     4861 ggcgctgctc gtcgccgtcc atcaggtcgt cgtgcagcag cgagaagttg tgcacgagtt
     4921 cgacggcgac ggcgccgggg atgccggcct cgggcggagc gcccgcggct tccgcggaca
     4981 gcagggcgag cgcggggcgc acggccttgc cgccgtcgcc gtcggccggc cggccctggg
     5041 cgtcgatcca gccgaagtgg tacgccgcga cggtgtccat gggcggcgcc agccggtcca
     5101 cggcagctcg cagcaccggc gttgacaggg cccttccacg ctccagaagc gcggtgacgt
     5161 ccgtggtgtc cgccacggtg tcgtaagccg gattcgccgg ggtcacagac tctcctcttg
     5221 ttccggtggt actgctcatg ccgcttcctg cagcggatgt tcgtggggtc gtccgagggt
     5281 gtggagcgcg gcgtccgcgg cactgaaacc gctgcggacc gcaccctcca tcgtggcggg
     5341 ccagccggtg gcagtccatg cgcctgccag atggagtccg ggggcacggg tgtgcgcacc
     5401 cggcctcagc cgccccgtcc ccggagcggg tgcgaacgtc gcggtgcgct cgcgggtgac
     5461 gaagaagtcg cggacaccgg cgccgcgcgc ggcggggagg agcttctcca gctcgggcag
     5521 gtagcgcctg cgcagctcgg cgacgggcag gtcgatctcg tcctgggccg cggactggga
     5581 caccgcgagg tactgcccgc cgccccggag cccggacgtc gcggtgcggt cgaagaccca
     5641 ttgcacgggc gagccgagcg cggcgaagaa cggccggcgc agcaccttgc ggtcgtagac
     5701 gacgtgcacg ttgaggatcg gcgcgtcggt cagttccagg agccggccgg ggtcgtcgat
     5761 cgccccgtcc ggcagcagcc cgtgggtctc gccctgaggt acggcgagga cgacggtgtc
     5821 ggcctcgaac cgtgagccgt ccgtcccgac ggcccaccgg ccgtcctcgg tgcgggtgag
     5881 ggagccggcc cgggtccgta cgtggagccg tacgcccgcc gactcgaggg ccttgcgggc
     5941 gagggtgtcg tgcagctcgc cgagcggcac ggcggcccag ccgatgtcgg cggcgccggg
     6001 ctcggagagc agccccgtct tgaagaccat cgcggccagt gccatggagg cgtcgggggc
     6061 ggtggcgttg agcgtggcga cgccgacgag gtcccagagc gcctcgacgg tccgctgcga
     6121 ctggccgttc cggcgcagcc aggtcgcgaa gtcgatgccg tcgagcgcgg ggtcggccgg
     6181 gtcgagccgg cccagcgcga gtgccgcgcg ggcgacgccc gccttctcgg cgagcgtgag
     6241 gtgcgggtag gcggcgagcc cgccggcgag gtgcaggggc acgggcagcc cggtgcggcg
     6301 cagccgtccg agcctcggcc cccgggcccg ccccacatcg agtacgggga cgtcgagacg
     6361 ctcctgcagg ggggcgaggt gggtgccttc gatgcggtcc aggaaccagc ggtaggcggt
     6421 gcagcagcgc aggaagacgt gctggccgtt gtcgacggac agctcgccgc ggcggaagga
     6481 gaaggccagg cctcccagcc gggggcggcc ttcgagcagg gtcacgtcga gcccggcgtc
     6541 ggcgaggcgc agggcggccg tcactccggc gagaccgccg ccgacgacca cggcacgcga
     6601 ggagcgcggg tcctgaccgg tcatgtgtgc tccctccgtc gcgccgtcgc actcagggac
     6661 gcgtggggcg ggtgcggggt tgcccgctcg gcgtggtcca ccgggcgcat caggccctcc
     6721 cccgggtggt ccggcgcgag atgtaccgcg cgtccaggcc cgacagcccg cgcacggcga
     6781 cgtacgcctt ctcgtggccg ggcagggaaa ccctgccgcg caggacggcc tcggggtcgc
     6841 gctcgatccg gtcgaggagc cggcggtaga tgccggccat ggccgccacg caggcgccgc
     6901 tgcgccggtc cagcatgggc agcagccggt agccctcggc gaagagggcg cgggcgcgcc
     6961 ggacctcgaa gtgcaccagg ccggcgaagt cggagccggg gggcggggtg gcccggtgga
     7021 agccggcgga gcagccgaac ttggcgaggt cgtcggcggg caggtacgtg cgcccgttgc
     7081 ccgcgtcctc acggacgtcg cggaggatgt tggtgagctg gagtgcgagg ccgagggtgt
     7141 cggcgtactc cgcggcccgg tcggccccgg gtgcgccggg ttccgtgccg aagacaccga
     7201 ggctgagccg cccgatggcg cccgcgacgc accggcagta ggtcctgagg tcgtcccagg
     7261 tctcgtagct cgcaccgcgc acgtccatga ggacgccgtc gatcagctcg tcgaggccgc
     7321 cgagcggcag cgggaaccgg cgcgcggcgt ccgccagcgc gacggccacc gggtcggtgt
     7381 cgtcctcgtc gaccgcgccg tcgcggatcc ggccgaggag ctcgcgggtg tcctccagcc
     7441 gggtccgctt ggtctccggg gccagctcgc cgtcgccgat gtcgtcgacg cggcgggaga
     7501 aggcgtacag cgccgacatg gcctgccgct tctcgtacgg cagcagtctg atgccgtagg
     7561 cgaagttacg ggcctgttgt ccggtgacgg cctcgcagta gctgtacgcg gcctgtaccg
     7621 gtgccgacat gtacgtcgtc tgtccctcca cggtccggct cacccctctc tgtacgcttt
     7681 tcgcaggact actcccactt cgcgcagcag acgcggcgcg gtgggcttgg gcggtccggg
     7741 cagtacgtcg aatccggcgg cggcgacggc ggtgagcgct gcccgccctc cgccgacgaa
     7801 gccggcgagc aggagcctga gcctgccccg gacgctgccc accagaggga tcccctcgtc
     7861 cagcaggtcg tgggcacgct gcgcctcgaa cgcgaccagg gcgcgcagcg acgctccccc
     7921 ggtcggtgcg gccaggtcgg attcggagac gtggaagcgg gccatgtcct ccgcgggcag
     7981 gtagatccgg tcccggccga ggtcctccgt gacgtcctgg aggtgctcgg cgatctgcag
     8041 cgcggtgcag acggcgtcgg agcggcggat ccgttcggga ctcgcggtac cggtgatctg
     8101 caggacgagg cgtccgacgg ggttggccga gagctcgcag taggcgagga gctcttcgta
     8161 cgtcccgtag cggcggacct tctggtcctg ccggttggcc tcgatgagcc cgaggaaggg
     8221 atcgggggtg agggcgcagc gccgcacggt ggggagcagg gcgcgcatca gggggtggag
     8281 cgggccgcct gcggcgtccg cgaagacgcg gtgcagatcg gcctcgaggg cgtcgagcag
     8341 ggcgagccgg tcctcggccg tgccggggcc gacgccgagg tggcgggcgt ccgcaccgcc
     8401 gggcgcgagg tcgccgtcac cgatgtcgtc gacgaggcgg gcgaagccgt agaccgccat
     8461 caggtcgtcg cgccaggcgc ggggcaggaa gaagggggcc acggggaagt tctcgtccgc
     8521 ggccttgtcg agggtggagg tggcgtcggt acgcgcctgc tgcgtacggg tcactgcgta
     8581 ccgcccgacg cggggacggc gaaaccacgt cggagctgga gatttcccat cattgccgtc
     8641 atatctcccg ttctacactg ctgacccaaa acatcccttt tcggacacgc cgctcactgc
     8701 cccgagtgcg acaggctcac aacggccgat gcaccggggg gcgtatcacc ccacatggcc
     8761 gcgaatcagc tcccgcacag cttacgttgt acagctcacg gggccgcgcc ggggtgcggc
     8821 gcgtcccggc acaacacttc gatctccgtc aaccttcccc gggatcaagg taattgacgt
     8881 catccgacgg gaggagatac cccccctggc gtccccgcga cccgggccac cacgcaccgc
     8941 agtggccccc gcctcggtgc accggcgggg gccacgggaa cggagggacc tacttgccgg
     9001 tctcccgctc gtacgccttg agcacctctt cggtggggcc gtccatcagg agctcgcccc
     9061 gctccagcca cagcacccgg tcgcaggtgt cccggatggt cttgttgttg tggctgacga
     9121 ggaagacggt gcccgcctcc ttgcgcagct cgcggatccg cgcctcggag cggacccgga
     9181 acttgcggtc accggtggcc agcgcctcgt cgatcatgag gacgtcgtgg ttcttggccg
     9241 ccgcgatcga gaagcgcagt cgcgccgcca tgcccgagga gtacgtccgc atgggcagcg
     9301 tgatgaagtc gcccttctcg ttgatccccg agaagtcgac gatgtcctgg tagcgcgagc
     9361 ggatctcctc gcggctcatc cccatcgcga ggccgccgag cacgacgttg cgctcaccgg
     9421 tcaggtcgct catcagcgcg gcgttgacac ccagcagcga gggctggccg tccgtgtaca
     9481 ccttgccgtg ctcggtcggc agcagcccgg cgatggcccg gagcagggtg gacttgcccg
     9541 agccgttggt gccgatgagg ccgatggcct gaccacggta ggcggtgaag gagacccccc
     9601 gcaccgcgtg caccttgcgg acgccgcgcg gctcgccctt gccgcggcgc atgatccggc
     9661 tgagcgccgc ggtggcgctg cccttgccgc cccccgtccc gttgacccgg tacacgatgt
     9721 gtacgtcgtc ggcgatcacg gtggggatgt gtccctggga agattcctca gccacggccg
     9781 taccgttcct ctgccttcca gaagtacacg aagcccagga cgcccaccag gagcgaccag
     9841 gcgagtccca cggcccagac gtgctgcggc aggttctcgg agccgtagcc gtcgatcagc
     9901 gcgaagcgga ccaggtccat gtagacggcc gcggggttgt actgcagcac gtccgcgatc
     9961 cactgcggct tgtcggccag catcaccggg atggagaaca tgacgcccga ggcgtacatc
    10021 caggtacgca tgacgaacgg catcagctgc gcgaggtccg gggtcttgct gcccagccgg
    10081 gccatgacga gcgccaggcc ggtgttgaac aggaactgca tggcgagcgc cgggacgatc
    10141 aggagccacg agagcgtggg atagctgccg aaggcgatcg ccacggcgaa cagcacgatc
    10201 atcgagtaca gcagctgctg gagctgctgg agcgagaacg agacgggcag cgaggcacgc
    10261 gggaagtgca gggccctgac caggccgagg ttgccggcga tggaccgcac ccccgccatg
    10321 accgagctct gggtgaaggt gaagacaaac acacccgtga ccaggaacgg gacgaagacc
    10381 tcctggctca tccccctgct ggtgccgagg atgatcccga agatcaggaa gtagacgagg
    10441 gcgttcagca gcggggtggc gacctgccac agctggccga gcttggcctg gctgtactgc
    10501 gcggtcagct tggccctgga gaacgccagg atgaagtgcc ggcggcccca gagctgccgg
    10561 acgtacgcga acagcccggg cctggcgccg ctcaccgtca agccgtactt ggcggccagc
    10621 ccggaggcac tcagcccctc gtcggcggac ggcgggctgc tcagcgcaat cccgccgtcg
    10681 tgggtcgtat cactcacagg taagaactct cgtcttcaca atgcgcagcc ggacgcgggt
    10741 gcggccgagg cggacaggtc cccgtacaca acgaaacagg gctcatggtc tcagaggaga
    10801 gcctctcaga tcacaggcgg tcggcccagt ctggtcaggc gccacaccgt acgccacctc
    10861 atggggcgcc ggggtccgca gggcttcgtc cacccttccc ggaaaccgcc gaaccacgcc
    10921 ctcagcgcgg gcagggaggg cttgcgcacc agcgtgagca gcagccagac cccgacgtac
    10981 acggggacca gcggtgccgg caggttccgg cgggccagcc agacccggtt gcgggccacc
    11041 atgcggtggt agaccgcgtg ccgtgacggg gcggtggtgg ggtggttgag caccatgtcc
    11101 gcgcggtagt cgatcatcca gccggcgtcg agggcccgcc aggcgaggtc ggtctcctcg
    11161 tgtgcgtaga agaagtcgtc ggggagcggg ccgacctcgg cgatcacccg ggtacgcacc
    11221 gcgttggccc cgccgaggaa cgtcgtcacg cgggaggagc gcatcgggtc tgccgcacgc
    11281 agccgcggga cgtgccggcg ctgggtgacc ccggtctcgg ggtcggcgat gcggaaggtg
    11341 atgatgccga gctccgggtc cgccgcgaac gcctgccggc acagctcggc tgtgtcgttc
    11401 ttcgccagca gcccgtcgtc gtcgaggaac agcagcacgt ccacgtcggt gccggaggcg
    11461 ccgaacgcct cgatgccgac gttgcgtccg ccggggatgc ccaggttctc gggcagctcc
    11521 acggtccgca cacccgcggg cacgtcgggg accggggcgc cgttgccgac gacgaccacc
    11581 tcgatccggt cgccgttctg cccggcgacc gagtcgagga gggcacgcag ctcgtcgggc
    11641 cggttgccca tggtgatgat gactgcgccg attttcatgg gtgagctcac ttcagcctgc
    11701 tggacgccag gatcgacacc aggtgcagga cggtctggag aagggcgatg ccggccatga
    11761 ccgcgaccgc gagacggctg aagaagaagt cgtccctgac ggtgtcgagc acggccacca
    11821 ccaggatgac cagcgacgcc tcgatgccga ggatcagccg gtggaacttg agcgcaccgg
    11881 ccgcccggcg ggccagcgcc atgccggagg agcgcggctc ggacgcggat tccttgacgg
    11941 ggggcagccc gccttggtgg cgggcgacgc cgacgaggtc ggtctcggcc ttgatcagga
    12001 tggcgcccag cgcggcgagc gtgcccagga aggcccacag ccagtcgatg cgccccgggc
    12061 cccacaggtc ggcggcacgc aggccgaagc cgaccagcac cgccgcgtca cagagatagg
    12121 cggccacccg gtccaggtag accccgccca gggagtactg cttcttccac cgcgccacct
    12181 cgccgtcgac gcagtcgaac agcaggtaga gctggaccgc gaccacgccg agcagcgcgc
    12241 ccgggatgcc cgggaccagc agagccggag ccgcgagcac accggcgacg gtcatcacgt
    12301 aggtcagctg gttgggcgtg accttggtgg tcaccaggcg ccgggtgatg cgcagcgaga
    12361 tctcgcgcat gtagagccga cccgcccagt gctcgccgct gcgccggtcc ttcacacccg
    12421 gagggtgcac gaccggacgg agttcagcta tggatggctt ttgcatagtc ggcgtacgcg
    12481 tccctgatct ggtcggtgga caggttgagg tgttccagga tcgtgaagcg tcccgggcgc
    12541 gtctgcgggg cgtactcgac ggcccgcacg aactcgtcgg gggtgaaccc gatctcgccg
    12601 ggcagcaccg gcagcccgtg gcgccgcagt acggaagcca tgtgcagcga ctcctcgcgg
    12661 gcgccccgca ggtgcatggc gaagcaggcg ccgaggccga cctgctcgcc gtggcttgcc
    12721 gcgcgcttcg ggtacagcag gtcgaaggcg tggttgatct cgtggcagcc gcccgaggct
    12781 ggccgggagt ccccggcgac cgacatcgag atgccggtca ggacgaggcc ctcggccagc
    12841 accttgagga aggcgtcgtc gccgaccccg ccggggtgac gcagcactgc ctcgcccgcc
    12901 tgccgggcca tggcggcggc gagtccgtcg atctcctcgc cctggatctc gtgggccagc
    12961 tcccagtcgg cgacgcagga gatgttggag accgcgtccc cgatgcccga gcgcacgtag
    13021 cgcgcggggg cctcgcggat cacgtccagg tcgatgacca cggcgatcgg ggtggggacc
    13081 ccgtaggagc cgcgtccgtt gtcgttgtcc agggtcgcga ccggggagca gagcccgtcg
    13141 tgggacaggt tcgtcgcgac ggcgaccatg ggcatgccga cccgcgccgc ggcgtacttg
    13201 gccacgtcga tgatctttcc gccgccgagg ccgacgaggg cgtcgtagcg gttgcccttg
    13261 atgccgtcgg cgagccgcac cgcggagtcg atcgtgccgt cgccgacggg gtaccagtcg
    13321 gcccccggca gcaccggcgc gagcctctcg cggagggcga gtccggaacc tccgctgatc
    13381 gcgatggcga gcttgcccga cgcggagatc cgctggtcgg cgaggagacc ggccagatcg
    13441 tccatcgcgc cgcgacggat gtcgacgacg accggggacg ggatgaggcg cgtcagtaca
    13501 ggcacgcgat ctccctgccc cgggcgaggt cgtcgtggtt gtcgatctcg acccacgtga
    13561 cctctccgat gggggcgacg tcgaccgtga agccgcggtt cacgagctcc tggtagccgt
    13621 cctcgtagta gaggtcgggg tcgcgctcga aggtggtcct cagcgcgtcg gcgagctcct
    13681 cggcggcctc gggctcgatc agcgtgacgc cgatgtactc gccggtcgcg gtggcggggt
    13741 ccatcagctt ggtgatccgc cggacgccct ggtcgccctc ggtgatgacc ttcatctcct
    13801 cgtcggcgag gttcttcacc gtgtcgaggg cgaggatgat cttctggccc ttgccgcggg
    13861 cgtccagcag ggtcctctcg acggagaccg ggtgcacggt gtcgccgttg gcgaggatga
    13921 cgccctgctt caggacctca cgggcgcacc agagggagta ggcgttgttc cactcctcgg
    13981 ccttgtcgtt gtcgatcagg gtcagcttca cgccgtacgt ggcctcgaac tcggccttgc
    14041 gggcgtagac cgcttccttg cggtagccga cgacgatcgc gacctcggtg agtccgacct
    14101 cggcgaagtt ggcgagcgtc aggtcgagga ccgtcttctc gccgtcgacg ggcaccagcg
    14161 ccttgggcag ggtgtccgtg tagggacgca gacggcgtcc ggcaccggca gccagtacga
    14221 ggccgatcat gcgagttctc cttcgtcgtg tacggcgggg gccgaggagg acacccagaa
    14281 gcggatggac tccacgagca ccaccagagc cacggccgcc gccagcgcgg tcagagccgt
    14341 ggtgaaagct gaggctccgg tcagcagggc ggcgagtacg gccacgacca gggtccggcc
    14401 ctcgtgcccg ccgatggtgc gcaccagcca ctggggcggg gcgcccgtac cgcctcggat
    14461 gcggtagacc gtgtcgtagt gatggtaggc gacggccgaa accaggccga atgccgccgg
    14521 aacggcgtgc ggtacgtcgc tgcgggccgc caggacgagg accgtgcagt actccgcggc
    14581 ccggaagacc gggggcacca gccagtcgag ggcgcccttg agcggccgtg agaccgcgag
    14641 gccggagacg accgcgtaca cccctgccgc gccgacggtc agccagctgc cgtagggcgc
    14701 gaagagtgcg gcggcgacca gcaccagggc tccggcgagc gccagcagcg gggcggtgaa
    14761 gccgccgccc ggacgccgga ccacggcggc gacggcctgc gcgaggggcc ccgagtcggc
    14821 gaggtcggcc agtgcacccg ctgcccggtc ggtgcgctgc gccttgcggg tcagcgagcg
    14881 gagcagtcgg ccggccgtgg tgtagcaggc ggccagggcg cagcccacga ggagggcgta
    14941 gaagacgatc cggggggtcg tcaccgcggt cagcacggcg atcatggccc agcgctcgcc
    15001 gatgggcagc actatcatcc ggcgcagcca gaccgtccag ccgacgctgt cgagcttgtc
    15061 ggagagcgcg gcggtgggac tcgtgttgga gaccgcgtcg tggttggcct cgttgaacga
    15121 gaagtcgacg acatggcggc aggcctggag gaccatcgcg ccgagcgcga ggacccatac
    15181 gtcgtcgccg ccgcgggcgg cgccgagcgc gagacccgcg tagtacgcgt actccttggc
    15241 ccggtcgaag gtggcgtcca gccaggcgcc catcgtcgag tactgcagcg agtagcgggc
    15301 gagctgcccg tcggtgcagt ccaggacgaa ggagaggagc agcagcaccc cggccgcgac
    15361 gtagccgcct cgggtgccgg tcgccgcgct gcccgccgcg atcagggcgg tgatcaggga
    15421 ggcggtggtg acctggttcg gggtgaagcc ccggcgggcg caccagcggg cgatgtagcg
    15481 ggagtacggg ctgatgaaga acgtggtgaa gaacccgtcg tgggccttca cggcgctgcg
    15541 cagccgtacc gcctcgtcgt cgacagcggc gacggcggac cggacggcag cgcggtcctc
    15601 ggggccgtcg ggtaccgcgg cggtgagcga gccgagctcg ggacgctgca cggcggtgcc
    15661 ctcggcgtcc agggccgcgg cgaggcggcc ggggaccgtg tggtcctcgg cggcgggttc
    15721 ggcgcccggg ggcgcgacgg ggcttcccgt gccgacgccc gcgccgacgg cggccaccgc
    15781 cgtgcgcagg gcgcccagca ccgcggcccg tgcctcgggc tgcgcggtga gcgctccggg
    15841 cacggtggcg acggcgaagc gggggtcggt cagtccgagc ctgagggcat ggacgtggcc
    15901 gacgaagcgg gggtccacga gcgcgacgcg ctggctcgcg ggaaccgcgg cgagcagttc
    15961 ggcggcctcg gtcgcgtcgg tggcggccct tacatcaaag ccgagtgacc gcagatcgtc
    16021 ctcgagcgac gatccgggta ccggcgcacc ggtgaggatg gcggtcgaca gacgaactca
    16081 ctccttggtg ctgacgggaa cagcccgcga cagtgcggcc cggagacggg ccggcggggc
    16141 gcatcggctg aggctatcgg atgaacggaa ggccgagttc accacccgtt tgtgctccgt
    16201 tcgggtgaag cggccatgat gcggcgccgt tcgcgatcat catcgtcgat cgatgccccg
    16261 ccccacaaac cgcgtcccgc ccgcggtcgg gcggccgggc ggggggaggt acgcggcggg
    16321 tcccccaccg gtcggcctaa gctgacgcgt atgacgtggt tgatcacagg cggggccggt
    16381 tacatcgggg cacacgtggc gagggccatg acgggggccg gggagaaggt cgtcgtcctc
    16441 gacgacatct cgacgggtat cgccggccgg ctgcccgcgg acatcgagct ggtgcgcggt
    16501 tccgcccacg accgcgggct gctcgaccgg gtgctggccg agcacgcgat cacgggtgtg
    16561 gtgcatctcg cggcgaagaa gcaggtcggc gagtccgtgg agaagccgct gctctactac
    16621 cgggagaacg tcaccgggct cgccgtgctg ctggaggccg tggtcgcggc cggtgtgcgg
    16681 cagttcctcc tctcctcgtc ggcggcggtg tacggcgtgc cggacacgga cctcatcgcg
    16741 gaggacaccc cgtgcgcgcc catcaacccg tacggcgaga ccaagctcgt gggcgagtgg
    16801 atggtgcggg ccgcggggcg ggcacacggg atctccacag cctgtctgcg gtacttcaac
    16861 gtggcgggta ccgaccggcc cgagctgtcc gacacaggtg tcttcaacgt cgtcccgatg
    16921 ttcttcgaca ggctgacgcg cggtgaggca ccgcggatct tcggtgacga ctacccgacg
    16981 ccggacggca cctgtgtccg cgactacatc cacgtcgccg atctggccga cgcgcatctc
    17041 gctgtggcgc ggaagctggc cggtcagggc gccggcgagg acctgaccgt gaacatcggc
    17101 cgcggtgagg gcgtatcggt gcggcagctc gccgacctgg tgggcgaggt caccggccgt
    17161 cccgtggagc ccgtggtcga ggcgcgcagg ccgggggacg cggcccgtgc cgtcgcgtcc
    17221 gccgaccgca tgaccgagga gctggggtgg acggcccggc gcggggtgcg cgagatggtc
    17281 gagtcggcgt gggagggctg gtgcctgcgc cacccggagg cccgcgccca gtgatccgcg
    17341 accccgggcc gatgctctga cctgcgaacg tttccgcagg tcagagcaca tgacaacggt
    17401 gttcaatgcc gtgttgcccg gtaccccccg cccgtagttc actggccaca tcgggcggtc
    17461 ggcgcccgag gggtacgacg cgttccggag gcgttccatg ggggctggcc acgatcacgg
    17521 gcacacgcac ggagggccgc ccccgacggg cacggccgcc gccgcgtaca agggccggct
    17581 cagggtcgcg ctgggcatca cgctcggcgt catggtcatg gagatcatcg gcgggctgct
    17641 ctccgactcg ctcgccctga tcgcggacgc ggcccacatg gcgaccgacg cgctcggcct
    17701 cggtatggcc ctgctcgcga tccacttcgc caaccggccg gccgggccca accgcacctt
    17761 cggcttcgcc cgtgccgaga tcctggcggc actggccaac tgtctgctgc tcctgggggt
    17821 cggcggttat ctggtcttcg aggccgtcga ccgcttcatc accccggccg agacccaggg
    17881 cggtctggcc atcgcgttcg ccgccgtcgg cctggtcgcc aacgtcgtct ccctgtccct
    17941 gctgatgcgc gggcagaagg acagcctcaa cgtgcggggt gcctatctgg aggtggtcgc
    18001 ggacactctc ggctcggtca cggtgctcgt ctcggcgggc atcatcatgg ccaccggctg
    18061 gcaggccgcc gacccgatcg cctcgctgct gatcggcctc atgatcgtcc cgcggacggt
    18121 gaagctcctg cgcgagacgc tcaacgtgct gctggagtcg gcccccaagg gcgtcgacat
    18181 ggaagaggtg cgcgcccaca tcacggccct gccgggtgtg ctggacgtcc acgacctgca
    18241 tgcctggacc atcacctccg gcatgcccgt gctctccgcg cacgtggtcg tccaccagga
    18301 gatgctggac tcgatcgggc acgagaagct cctgcacgat ctgcagggct gcctgggcgt
    18361 gcacttcgac gtcgagcact gcaccttcca gctggagccg agcgggcacg cggagcacga
    18421 ggcgagactc tgccactgag cccggccggc cggtgctagg gttccgccgt cacgtccgtg
    18481 cacccggacc cgaagtgaga aggagctgag gttgatgact gtccagacga ctgctgcccg
    18541 gcgcagccac cggtccttcc tcatctcccg ggtt
//
