LOCUS       NZ_LMEI01000006        23219 bp    DNA     linear   CON 26-MAY-2024
DEFINITION  Streptomyces sp. Root431 contig_2, whole genome shotgun sequence.
ACCESSION   NZ_LMEI01000006
VERSION     NZ_LMEI01000006.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root431
  ORGANISM  Streptomyces sp. Root431
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 680762)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 680762)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140605
            Assembly Name                     :: Root431
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001426585.1-RS_2024_05_26
            Annotation Date                   :: 05/26/2024 02:21:26
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,904
            CDSs (total)                      :: 5,829
            Genes (coding)                    :: 5,744
            CDSs (with protein)               :: 5,744
            Genes (RNA)                       :: 75
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 2 (5S)
            tRNAs                             :: 66
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 85
            CDSs (without protein)            :: 85
            Pseudo Genes (ambiguous residues) :: 0 of 85
            Pseudo Genes (frameshifted)       :: 22 of 85
            Pseudo Genes (incomplete)         :: 72 of 85
            Pseudo Genes (internal stop)      :: 1 of 85
            Pseudo Genes (multiple problems)  :: 10 of 85
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 08:56:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 230331
            Orig. end                         :: 253550
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMEI01000006.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23219
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="1"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..23219
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23219
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:13219](-)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13219)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     gene            454..630
                     /locus_tag="ASC82_RS30330"
     CDS             454..630
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC82_RS30330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157863440.1"
                     /transl_table=11
                     /translation="MPGPGFTVGLLGGLVYAHASPVSPGGAYQIPALGIDVVTAPAARR
                     RVRRDRPPARRHP"
     gene            798..1208
                     /locus_tag="ASC82_RS05520"
                     /old_locus_tag="ASC82_04910"
     CDS             798..1208
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.4"
                     /locus_tag="ASC82_RS05520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04910"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_242427559.1"
                     /transl_table=11
                     /translation="MQLIPRHDPHLVVRSAGGTTVAVLRGELDLVLVRHLRPELDALVR
                     ESDALTLDIRRLGFCDATGLGLLAHCAGRVQARGARWRLICDQPWILRLIRLTALGELL
                     RPEPAAPGDHPAVITPHDPAREPREYGFPSQG"
     gene            <1260..1663
                     /locus_tag="ASC82_RS05525"
                     /old_locus_tag="ASC82_04915"
                     /pseudo=""
     CDS             <1260..1663
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004004232.1"
                     /locus_tag="ASC82_RS05525"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ASC82_04915"
                     /product="ABC transporter permease"
                     /pseudo=""
                     /transl_table=11
                     /translation="LIVMLTVMLVVVACLGCSTRSSWTPANGSVTWASTRRWE"
     misc_feature    1261..1275
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.42"
                     /tool="antismash"
     misc_feature    complement(1261..1281)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.05"
                     /tool="antismash"
     gene            1719..2234
                     /locus_tag="ASC82_RS05530"
                     /old_locus_tag="ASC82_04920"
     CDS             1719..2234
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1278: PadR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573967.1"
                     /locus_tag="ASC82_RS05530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04920"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_056642371.1"
                     /transl_table=11
                     /translation="MSEVRLTTPSFLVLGIIDQLGEASPYDVKVEAARTVAPFWSMPHA
                     QVYAQCDRLLEAGLLSEVRQSGGRNRRLMKLTEEGAAALRGWLADSSFVPVEARERGIL
                     KLWFGASPRVHAPVQVEEHQRTLGEYEELAEGVGELLSRGQREALEFGIRYERMMVDFW
                     QWVETREP"
     misc_feature    2236..2253
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.05"
                     /tool="antismash"
     gene            2327..3532
                     /locus_tag="ASC82_RS05535"
                     /old_locus_tag="ASC82_04925"
     CDS             2327..3532
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573966.1"
                     /locus_tag="ASC82_RS05535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04925"
                     /product="DUF2306 domain-containing protein"
                     /protein_id="WP_242427560.1"
                     /transl_table=11
                     /translation="MGRPTSTRRGRAAALAITVVCLAYAPIAATELWPYASPGAPAIGE
                     WLLGRTVSPEFVADAVRDRMGPYTRSLAPLILHSVLGGLLMLLGPVQLLSAVRRRIRLH
                     RITGTVFAVTVYVSMAGAALYLVRTPPEQAFSGAAFWIVLATILVGTVGSVTLGVLAAV
                     RGFPDLHQRWLLLCYGFLMTAPLLRLEWGFLPALYPGLSLQDINRVAIMHLGSLVSFGA
                     LLASRALDRRTTVPGLTGTWCPGPVMAAVHLAGAAGLTWITVAFLDQGTGGRRLLLAYA
                     VPYAATYAVIAVRAARARGAHWAREEWRLHLAALCLAPAFSAVAVPVLERTMGLDRLTA
                     LIAGVGIGGGMLAYAAVTVVSLRVLYGRELLKRQEAFTAGPTDHSPLPVAATALAREGE
                     DR"
     gene            3529..4461
                     /locus_tag="ASC82_RS05540"
                     /old_locus_tag="ASC82_04930"
     CDS             3529..4461
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC82_RS05540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ASC82_04930"
                     /product="hypothetical protein"
                     /protein_id="WP_056642373.1"
                     /transl_table=11
                     /translation="MSDTEKPVRDDAGTLDGRELSPAVVILSSVVGGISLTVGALLAVT
                     SLTGHAAGAWVSPEALSPGLVGAAMAGVAPALFTLGKARVWEEARTLVLPLVIVLVGLF
                     AVSLLNGGSLQAVHGGPLFLALFSLGWVATLGLLALAAVVCLAAQYRRPAPPSGAERPR
                     VAPLPGWSKPLLAVLGSGWFGIGAGLLAFPAFWGPLVPWTVNRADAQGLGVWALALGVG
                     VLGSLVEDDLARIRPALTAVPAVALATAVVLAVHARTVDWTSGPGISLLALVAGLLTTG
                     VSGRLLLTKAGAAGEDGKEPASAAVRRKE"
     misc_feature    complement(4545..4560)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 20.63"
                     /tool="antismash"
     gene            4593..5201
                     /locus_tag="ASC82_RS05545"
                     /old_locus_tag="ASC82_04935"
     CDS             4593..5201
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018521093.1"
                     /locus_tag="ASC82_RS05545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04935"
                     /product="isochorismatase family protein"
                     /protein_id="WP_056642377.1"
                     /transl_table=11
                     /translation="MTQHTQPVDALIVVDVQSAFVVGDGAVPAADRLVDRTTDLIARAR
                     KDGALVVHLQNDGPPGSEDEPHTPGWELHHPVEPGPSEFVIRKPQDDGFHETPLGGVLT
                     DAGVTAVAVCGVMSEMCVQATARTALARGYRVVVPYDAHATQDCPAVPGVHEVVPAATV
                     SRVAAYALGSDAEVTVSAADVTFTAPAASPATGAAPDLR"
     misc_feature    complement(5260..5277)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 23.36"
                     /tool="antismash"
     misc_feature    complement(5282..5298)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.38"
                     /tool="antismash"
     misc_feature    complement(5288..5302)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.04"
                     /tool="antismash"
     misc_feature    5292..5307
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.42"
                     /tool="antismash"
     gene            5373..5759
                     /locus_tag="ASC82_RS05550"
                     /old_locus_tag="ASC82_04940"
     CDS             5373..5759
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031971.1"
                     /locus_tag="ASC82_RS05550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04940"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_056642380.1"
                     /transl_table=11
                     /translation="MTIEWRYTVQQELGVLSLAGFLGGDALGRFTGAVGWAVARGTGPV
                     VLDLSRLRGWSAGGQHAVAEAAHRLRAAGRSLELAAIPADGSLVPAGEGPAIPVHCDLD
                     AAFAAHLDAGAEQRAWRSDAWPSE"
     gene            5918..6259
                     /locus_tag="ASC82_RS05555"
                     /old_locus_tag="ASC82_04945"
     CDS             5918..6259
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012381360.1"
                     /locus_tag="ASC82_RS05555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04945"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_056642383.1"
                     /transl_table=11
                     /translation="MAAPLYQLKAEFFKTLGHPVRIRVLELLSQREHAVAEMLRDTGVE
                     AAYLSQQLAVLRRANLVVARREGVAVHYTLTSPRVAELLLVARSILSGVHAGQAEPLAD
                     LRSRSSSTP"
     gene            complement(6288..6836)
                     /locus_tag="ASC82_RS05560"
                     /old_locus_tag="ASC82_04950"
     CDS             complement(6288..6836)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956470.1"
                     /locus_tag="ASC82_RS05560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04950"
                     /product="alkylhydroperoxidase"
                     /protein_id="WP_056642386.1"
                     /transl_table=11
                     /translation="MTTRRLTALTPEQAPGRAREVLGDIVERHGSVGEMVSTMAHSPAL
                     LDGYLSLSRAMKRVKIPRALSEKLSLAVQEWIGCGTCREAHVSAGRAAGLSDTDIALAR
                     QGTSTDPREAALIGLALKVLAEPGSLSDDDVAEVRAHGWSDRVIAEVVGVVTLNLLTGA
                     FNLLAGIQPEKEEESKPGE"
     misc_feature    6851..6866
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: medium, score: 25.93"
                     /tool="antismash"
     misc_feature    complement(6851..6867)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: medium, score: 26.83"
                     /tool="antismash"
     misc_feature    complement(6852..6867)
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 23.35"
                     /tool="antismash"
     gene            complement(6901..8193)
                     /locus_tag="ASC82_RS05565"
                     /old_locus_tag="ASC82_04955"
     CDS             complement(6901..8193)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019890954.1"
                     /locus_tag="ASC82_RS05565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04955"
                     /product="cytochrome P450"
                     /protein_id="WP_079039115.1"
                     /sec_met_domain="p450 (E-value: 4.2e-17, bitscore: 57.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGRTGRPGTVSGGPPEPPEPFDPARLDLADPYPVYRRYRETDPV
                     HAVRGGHGGAAPTTWYLFGHAEVAHVLAGRSFGRTSPLTARSAPVPDGYVTLRRVVENW
                     LVFLDPPRHTRLRARVTPPLGAAAVAALRPRVREIAEELVAPLARRPVVELVEGFAAPY
                     PLLVIGGLLGVEAERWPWFREQALALQQAGGTRGDRTPAALDGAERAAAELDGYFHREL
                     AARRTEDRGDLLSALARAGAEDPSLSGSELAATCTHLLTAGHETTTGLIGKAVLALLDR
                     PEVRDELRADPGLLPNAVDEFLRHDPPVQMVTRWAHRDTELAGRTVRRGDRLQLVLGSA
                     HRDPDRFPDPEVLDIHRDSGRHCAFGLGIHYCAGAALARAEAEIGLGVLLDRLPALAPG
                     ARPGVEVEYAPDWVFHGPSRLTLSCRPSLHS"
     CDS             complement(8190..>8611)
                     /codon_start=2
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031968.1"
                     /locus_tag="ASC82_RS30780"
                     /note="incomplete; too short partial abutting assembly gap;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="GSGGSGGSGGSGGSGGSGGTVAPAGSDGPVWNRTTLPGVRAPHAW
                     LGPGRSTLDLFGGEFVLLCFGDGYGDGGGTVDGLVRAFADRRVPLRVRHCRDAEVARRY
                     ERPFVLVRPDGHVAWRGAAPPADPLRIADLVRGAGG"
     gene            complement(8190..>8613)
                     /locus_tag="ASC82_RS30780"
                     /pseudo=""
     assembly_gap    8614..8624
                     /estimated_length=11
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<8625..9996)
                     /locus_tag="ASC82_RS05570"
                     /old_locus_tag="ASC82_04960"
     CDS             complement(<8625..9996)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963464.1"
                     /locus_tag="ASC82_RS05570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04960"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_079039116.1"
                     /transl_table=11
                     /translation="MSDNGRTRRRTEETEVLIVGGGPVGLALALDLTHRGVDFVLVEAG
                     DGRVAHPKVSTVGPRAMEAFRRWGVADAIRGAGWPADHTLDVAWVTAVGAYELHRLRLG
                     TAGDRPPPAYTPEPEAICPQHWLAPLLTERLGVRPLGPVRLGTRLVELDRKPDRVGAAL
                     VDGEGVRTTVHARYVVGCDGASSPVRKACGIDAPERHRTRTLRNILFRCPGLGALLGPR
                     AALVHFVTEPGGLRYPLRAMDGRELYRLTCPAGPADAERVVRRALVLDVPVEVLSDTTW
                     HLTHRVASRYRDGRVFLAGDAAHTLSPSGGFGLATGVGDAADLGWKLAAELAGWAGAGL
                     LDTYESERRPVAVNSLEESHRNLRRTVDRRLSAALRDDTEEGERARAALGREIADSDPL
                     REFDAPDLHFAYRYASPAITDEKDGAVPAGGSGGSGGSGGSGGSGGSGGSGGSGGSGG"
     gene            complement(10001..13219)
                     /locus_tag="ASC82_RS05575"
                     /old_locus_tag="ASC82_04965"
     CDS             complement(10001..13219)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indsynth"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031967.1"
                     /locus_tag="ASC82_RS05575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04965"
                     /product="ferritin-like domain-containing protein"
                     /protein_id="WP_056642388.1"
                     /sec_met_domain="indsynth (E-value: 0.0, bitscore: 1250.6,
                     seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVFDLPRLHFGGTAVTRLPTGPNGGLVDLARNTALRGAGGGSER
                     PSAVGPFGEDGPAEAFHEHLAEHGARGGHFSGNGHLVLDARVTGVERADGAVETADPVV
                     GRAVDLWGHYNPYLGTTVNRARVFDVDPASAWTTTLMGGRFAFGREGRSHDAGYLCVGD
                     VGGFMPPRWHGFTPVRRTLHQFAIGAGEGLDWPAGAADSPAVRALRAAVEECEGGGIVV
                     QFVLERPAAPPEGVREPVDAPGVWRLRGTVAPWRPDEPRTHPAGRLLVPHGRESHADGT
                     PGPCTVRVSPDSVAFNWPFAHRLDATGAAVRDGGPALELRTARSDLPVAVLPAGAAEGG
                     AVVTVPAGSAEGVRRAAEEGLVLVRPAADGGDGRAVLLREREAVVLTDEACLILEHPDP
                     ERGEEHAVEVPVRTFLRGVPAALDGVVVRQFANPRALPLDPVASDAAARCGDVEIVRLR
                     AGRTAGEKPLAEEGPGGAGSSWCGLATDAHGRGWFTVSGARAGTARLLLAAGPEELPPH
                     DPAAPGSAEACYDHDDALGFWPWAGSAAVRVLPDDWQLDAVLQQDVTFELLHREVFAYY
                     EQLFPFMRDEVFSLADRCKVETYAKLIWQMCDPANKDRTYYMPPTRDLSLPKARLLLKY
                     LRAQSAAAAVPPAAVPSPVRSYPQITTRAQLRSALWQAVTVELATSLQYLYAGYSVPTH
                     GTGFEYVRSGVWTPRQLRLACGDGGETLAKGVRDSLFDVAREEMMHFLVVNNILMAMGE
                     PFHAPEIDFGTPGRLPLPLDFALEPLHLGSLQRFIAIERPERLAGGTGRTDGPGPFGSP
                     SELYAGIREGLIRVPDLFPVDRGRGGGEHHLFIGGAVNAVHPDYQLEVDDLSSALFAVD
                     FVTEQGEGGVLDTEKAGSESHHETFVRLAELLMTERADGPHGEGAPWHPAYPSLRNPTL
                     APGHPGRAAVSDPHARQVMRLFNRCYFMMLQLIVQHFGESPDASLRRSKLMNAAIDVMT
                     GMMRPLAEQVMPLESGWRGRTAGPSFELEEPPAYIARPDVARRGFAMRFRHLAAMAREC
                     EGVPERVPELMTWYAERFAHEGRS"
     gene            complement(13216..14793)
                     /locus_tag="ASC82_RS05580"
                     /old_locus_tag="ASC82_04970"
     CDS             complement(13216..14793)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015031966.1"
                     /locus_tag="ASC82_RS05580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04970"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_056642392.1"
                     /transl_table=11
                     /translation="MQTSTVTQTVTQPAAVTRPGHVQQLLPRARRRTRANSTVSVVGAG
                     MAGLVAAYELERLGFRVEVIEGSRRLGGRVHTHRFGASEGAPFVELGAMRIPTAHHRTM
                     RYVEHLGLADQVRPFTTLLSEENAYLATSTGHVRLRDAPRALIADVRASLPGADYREET
                     VVFGAWLAAVVDAVAPPGLRAGLRADLARNLLDLVEDVDLSPHLLGHAKDRIDVHGLFA
                     AHPGIRAGCGTRLNGFLDDILTETSPELVRLACGMDQLVQRLAARVRGPIWLGQRVSGF
                     EVAADHVLVRIGGGPGAAVRRCDYVLCTVPFSVLRGLTLTGFDEDKLAVVREVDYCPAT
                     KVAVHCREPFWEREGIRGGASFSGGRIRQTYYPPAAADGAGTGGSTDPAQGAALLASYT
                     IGEDADHLGRMPPPLRHRTVVEELGRMHPQLLRRGMVRGVASLAWGEHPWTEGGCTIRW
                     GQDAAACEEQRRRAVRPQRRMFFAGEHCATEPAWIEGAVESALEAVDLIARHAPGRGVA
                     PRAGLEAA"
     gene            complement(14848..16572)
                     /locus_tag="ASC82_RS05585"
                     /old_locus_tag="ASC82_04975"
     CDS             complement(14848..16572)
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013646.4"
                     /locus_tag="ASC82_RS05585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04975"
                     /product="FAD-dependent monooxygenase"
                     /protein_id="WP_056642396.1"
                     /transl_table=11
                     /translation="MARLDTGRDGDAGGDGAKGSAGDVDVCVVGAGPVGLTLAIGLRRL
                     GLRVRIVDKAPATKREARALVLWARAREALDSLGVGETLRRHGVELEVVTIHARDRALG
                     ELTTGWARSAHARPLNIEQHDIERLLSEELARLGTRVEWNTELTDVKVHDDRAEFTLRH
                     EDGTVESAVAPWIVGCEGTASVVRDRLGIPFEGRRRTGLQVVQGNAQPTWQLGEEPGRG
                     HIFLAPHRSLLVFPLPGGGFRFFCFRDDPDPTLTTAPTIGELRDLVAETAGMPGLRLEA
                     TEHLWLNRARFSDRVAARLRSGRGLLAGDAAHAWAPVGGHGMNVGVLGAHNLAWKLAAV
                     HHGQAGEELLDTYSDEQRLLAVRYIREMRFNFMELPLPPLGYRVFTATVPAALARRGIQ
                     RRLDLRLSDLSRNHRDGALSRHRPGRHGRPGGPRAGDRMPDVALATGSAECGTGTAVQS
                     VASVAAVRLHTLLGYERWTLVLHAERADAGVLDALRETCDGFPAPVRVLPVTPWDGAEA
                     RRLGHPDDLRLVRPDGYVGLVAPLDRPALLRSYLVALAAEARMPVRRSEEHHPHRTH"
     misc_feature    16668..16684
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.65"
                     /tool="antismash"
     gene            complement(16910..18385)
                     /locus_tag="ASC82_RS05590"
                     /old_locus_tag="ASC82_04980"
     CDS             complement(16910..18385)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (150-473). E-value:
                     8.9e-27. Score: 86.1. Matches aSDomain:
                     nrpspksdomains_ASC82_RS05590_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /locus_tag="ASC82_RS05590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04980"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_199862472.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.1e-26, bitscore:
                     86.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARIASTRLSRLLTGWSSEGAGPLPRRLADALRELAERGDVPAGT
                     VLPSQRELALVLAVSRSTVTSAYGLLEAEGWLESVRGSGSRLRASGALDRYVAEGRLVS
                     FDARTGTGTAGIADLSSGALPGLGAVGEAVGALTSGDLGGLLVADGYHPYGIPALREGI
                     AAYYRAAGVPTEAGQILVTAGSQQAVWLVAQALVEPGDTVVVEDPTYRGALEALRARGA
                     RLVPVGTDGDGGGDGSGAAAVRRLSAHGRPRLVYLQPTVHNPTGRTLDGAARREWRRVL
                     GDLELFTVEDTACAELSLGVGEKAASGGPGDDGGAPEPLVAGLPMASTVTVGTLSKLFW
                     GGLRVGWVRSSPQVVARLAKIKTSVDLSCSVMDQLVAVRLLDRLPEARARRRAELRAQR
                     DTAEALLRSGAPHWEWTRPAGGAALWVRVPGADTETLAQLARRRGVSVVPGSAFSPVDG
                     FRDRLRLPYAHGTAALEAALPTLLECAERAAAG"
     aSDomain        complement(16967..17935)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASC82_RS05590_Aminotran_1_2.1"
                     /evalue="8.90E-27"
                     /label="ASC82_RS05590_Aminotran_1_2.1"
                     /locus_tag="ASC82_RS05590"
                     /protein_end="473"
                     /protein_start="150"
                     /score="86.1"
                     /tool="antismash"
                     /translation="YHPYGIPALREGIAAYYRAAGVPTEAGQILVTAGSQQAVWLVAQA
                     LVEPGDTVVVEDPTYRGALEALRARGARLVPVGTDGDGGGDGSGAAAVRRLSAHGRPRL
                     VYLQPTVHNPTGRTLDGAARREWRRVLGDLELFTVEDTACAELSLGVGEKAASGGPGDD
                     GGAPEPLVAGLPMASTVTVGTLSKLFWGGLRVGWVRSSPQVVARLAKIKTSVDLSCSVM
                     DQLVAVRLLDRLPEARARRRAELRAQRDTAEALLRSGAPHWEWTRPAGGAALWVRVPGA
                     DTETLAQLARRRGVSVVPGSAFSPVDGFRDRLRLPYAHGTAA"
     gene            18521..19771
                     /locus_tag="ASC82_RS05595"
                     /old_locus_tag="ASC82_04985"
     CDS             18521..19771
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020551151.1"
                     /locus_tag="ASC82_RS05595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04985"
                     /product="Tm-1-like ATP-binding domain-containing protein"
                     /protein_id="WP_056642402.1"
                     /transl_table=11
                     /translation="MATVVLVGTLDTKGEEYAWLRERLREYGSDVLLVDTGVLPPPAHA
                     PVPDVSADVVARAAGHDLARLRAAGDRGAAVSAMAHGLTRVVLDLYRKGKLHAVLAAAG
                     SGGSAIAAQAMRALPIGVPKMLVSTMVGGDVSPYVDSSDLTMMYSVVDISGLNAVSCQV
                     LGNAAAAAAGMARRYERNHDEPAGRGRPVVAATMFGVTTPAVDAARARLAELGYEVLVF
                     HATGAGGRAVEKLARDGMLDGVLDLTTTELADELVGGVLSAGPTRLTAAGVMGIPQVVA
                     PGALDMVNFGPAATVPERFTERRLLVHNATVTLMRTTAAEMAELGTGMGRKLRTARGPA
                     EVFWPLRGISAVDTADGPFDDPEADRAGLDALRAAVRGGEVRVHELDAHINDASFAVAM
                     ADRLHQLIAENTRGPGY"
     misc_feature    19897..19915
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 16.46"
                     /tool="antismash"
     gene            19900..20742
                     /locus_tag="ASC82_RS05600"
                     /old_locus_tag="ASC82_04990"
     CDS             19900..20742
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565367.1"
                     /locus_tag="ASC82_RS05600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASC82_04990"
                     /product="phosphoenolpyruvate hydrolase family protein"
                     /protein_id="WP_056642405.1"
                     /transl_table=11
                     /translation="MNTGSTVSRQDVLTRLRAQVAAGRPIVGAGAGTGLSAKCAEAGGV
                     DLLIIYNSGRYRMAGRGSLAGLLPYGDANAIVQDMAREVLPVVRDTPVLAGVCGTDPFR
                     RMDLFLDELKAMGFAGVQNFPTVGLYDGTFRVNLEETGMGYGLEVDMVRAAHERDLLTA
                     PYVFDPEQAADMAAAGADVLVPHVGLTTKGAIGAGTALTLDQAAAAVQEMHDAAKRVNP
                     DILVLCHGGPIAEPEDARYVLEHTTGVVGFFGASSIERLPTERAVTEQTRAFKALTLG"
     misc_feature    complement(22809..22823)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(23165..23179)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.35"
                     /tool="antismash"
ORIGIN
        1 tggccggcac cggccacatg ctcggcctgg acgtccacga ctgcgcgcac gcgcgcaacg
       61 aggagtacgt cgacggcctc ctggagccgg gcatggtgct cacggtcgag cccggcctgt
      121 acttccagcc ggacgacctg accgtgcccg aggagtggcg cggcatcggc gtccgcatcg
      181 aggacgacct ggtcgtcacc gagaacggcc acgagaacct gtccgcgggc ctgccgcgct
      241 cctcggacga ggtcgaggcg tggatggccg agttcgcggg ctgatccacc agggcttgtc
      301 cgactctgat ccgccggaca ggccctagcc gtacggcctt tcccggcacc ccctatcccg
      361 cgatgtcctc gtagagggcg aagagacgcg ggaggggggg ctgtcgtccg tggcgggatg
      421 ccgcgagagc gcggtccggc aggtcgccat gaggtgccgg gcccgggctt cacggtcgga
      481 ctgctcggcg gcctcgtgta cgcccacgcg agcccggtga gccccggcgg cgcgtaccag
      541 atcccggccc tcgggatcga cgtcgtcacg gcccccgctg ctcgccgccg cgtacgccgc
      601 gaccgtcctc cggctcgccg tcacccgtga accgggcgca ctcgttcgcc cgtgcgttcg
      661 gaaccggagg gggagagggc tccgaaaggc ccgcgtattc accggttcag gtgacagtgg
      721 tcgaggcgaa acgtccctcc cgggtcgcac gcggccacgc tcgacgggac acatggaccc
      781 accctgtgga gcgtccgatg cagctgattc cccgtcacga cccgcacctc gtcgtccgct
      841 cggccggcgg aaccaccgtc gccgtgctcc gcggtgagct cgatctcgtc ctggtgcggc
      901 acctgaggcc cgagctcgac gccctggtcc gggagtcgga cgccctgacc ctcgacatcc
      961 ggcggctcgg cttctgcgac gcgaccggtc tgggcctgct cgcccactgc gccgggcggg
     1021 tccaggcgcg gggcgcccgc tggcggctga tctgcgacca gccgtggatc ctccggctca
     1081 tccgcctgac ggccctcggc gaactcctcc gccccgagcc ggccgcgccg ggggatcatc
     1141 cggcggtcat cacacctcac gacccggccc gggagccccg ggagtacggc tttccgagcc
     1201 aggggtgacg agcccggtct cgtaggcggc gacgaccgcc tgggcccggt cgcgcaggcc
     1261 tgatcgtcat gctcacggtc atgctggtcg tggtggcctg cctgggctgt tcaacacggt
     1321 cgtcatggac acccgcgaac gggtccgtga cctgggcgtc cacaaggcgc tgggaatgac
     1381 cccgcgccag acggtcgtgc aggtcctcac ctccgtggga ggcatcggcc tcgtggcggg
     1441 cgccctcggc gtcccgctgg gcgtggcgct ccaccactgg gtgatgccgg cgatgggccg
     1501 ggcctccggc gccacgatcc cgcccgccga catcgacgtg tacggcgcgc ccctgctggc
     1561 gtttctggcc gccgccggag tggtgatcgc gacggccggc gcgctgctcc cggcgggctg
     1621 ggcggccagg acgagcacgg cgcgcgccct gcgggccgag tgagggacgt ccggccgccg
     1681 gggccggtcg gcggtgacca ccgcgatacc gtcgcggcat gtctgaagtc cggttgacca
     1741 cgccctcctt cctcgtgctc ggcatcatcg accagctggg cgaggccagt ccgtacgacg
     1801 tgaaggtgga ggccgcgcgc accgtggccc ccttctggtc gatgccccac gcgcaggtct
     1861 acgcccagtg cgaccggctc ctggaggcgg ggctgctgtc ggaggtgcgc cagtccgggg
     1921 gccggaaccg gcggctgatg aaactgacgg aggagggggc ggcggccctg cgcggctggc
     1981 tcgccgactc ctccttcgtc ccggtcgagg cgcgcgaacg cggcatcctc aagctgtggt
     2041 tcggcgccag cccgcgcgtc cacgctccgg tccaggtcga ggagcaccag cggaccctcg
     2101 gcgagtacga ggaactcgcc gagggcgtcg gggagctgct gtcgcgcggg cagcgcgagg
     2161 cgctggagtt cggcatccgt tacgagcgga tgatggtcga cttctggcag tgggtcgaga
     2221 cccgcgaacc ctgacttgtt accgaccggt tgaccccggc cgcctcccgc cctaccttcc
     2281 tccatagtcc agacaggact atcgcgcgtt cggaggggga accgccgtgg ggcgtccgac
     2341 aagcacgaga cgggggaggg ccgccgccct cgcgatcacg gtcgtctgcc tggcgtacgc
     2401 gccgatcgcg gcgaccgaac tctggcccta cgccagcccc ggcgcacccg ccatcggcga
     2461 atggctcctc ggcaggactg tctccccgga gttcgtggcc gatgccgtgc gcgaccggat
     2521 ggggccgtac acccgcagcc tcgccccgct gatcctgcac tccgtcctcg gcggcctgct
     2581 gatgctgctc ggccccgtac aactgctctc ggccgtacgg cgacgcatcc ggctgcaccg
     2641 gatcaccggg accgtcttcg ccgtcaccgt gtacgtgtcg atggccggcg ccgccctcta
     2701 cctcgtccgc acgccgccgg aacaggcctt cagcggggcc gcgttctgga tcgtcctcgc
     2761 cacgatcctg gtcggcaccg tcggcagcgt gaccctcggc gtcctcgccg ccgtccgcgg
     2821 cttcccggac ctgcaccagc gttggctgct gctctgctac ggcttcctga tgaccgcccc
     2881 gctgctccgc ctcgaatggg gattcctgcc cgcgctctat cccgggctct ccctccagga
     2941 catcaaccgc gtcgcgatca tgcacctcgg ctccctggtc tccttcggcg cgctgctcgc
     3001 ctcccgcgca ctcgaccggc gcaccaccgt ccccggcctg accggcacct ggtgcccggg
     3061 gccggtcatg gccgccgtcc acctcgcggg cgccgccggg ctgacctgga tcacggtcgc
     3121 cttcctcgac caggggaccg gcggacgccg gctgctcctc gcctacgccg tcccgtacgc
     3181 cgccacctac gccgtcatcg cggtgcgggc ggcacgcgcg cgcggtgccc actgggcgcg
     3241 ggaggagtgg cgcctgcacc tggcggcgct gtgcctggcc cccgcgttct cggcggtggc
     3301 cgtgcccgta ctggaacgga ccatgggtct cgaccggctc acggccctga tcgcgggcgt
     3361 cggcatcggc ggcggcatgc tcgcgtacgc ggccgtcacc gtggtgagcc tgcgcgtgct
     3421 gtacggccgt gaactcctca agcggcagga ggcgttcacc gctggaccca ccgaccattc
     3481 gcccctgccg gtcgcggcaa ccgccctcgc gcgggaagga gaggaccgat gagcgacacc
     3541 gagaagccgg tgcgcgacga tgccggcacg ctcgacggca gggaactctc gcccgccgtc
     3601 gtgatcctga gctccgtcgt gggcggcatc agcctcaccg tgggcgccct gctcgccgtc
     3661 acgagcctga ccggccacgc ggcgggcgcc tgggtgtccc cggaggcgct cagccccggc
     3721 ctcgtggggg ccgccatggc gggggtcgcg cccgcgctgt tcaccctcgg caaggcgcgt
     3781 gtctgggagg aggcgcgcac cctcgtcctg ccgctcgtga tcgtcctcgt cggcctcttc
     3841 gcggtgagcc tcctgaacgg cggcagcctc caggccgtcc acggcggccc gctgttcctg
     3901 gccctgttca gcctcggctg ggtcgccacc ctcggactgc tcgcgctcgc cgccgtcgtg
     3961 tgcctcgccg cgcagtaccg ccgaccggcc ccgccgtccg gagccgagcg cccgcgcgtc
     4021 gcacccctgc ccggctggtc gaagccgctc ctcgcggtcc tcggctccgg atggttcggc
     4081 atcggcgccg gcctgctggc cttccccgcc ttctggggcc ccctcgtgcc gtggacggtg
     4141 aaccgcgccg acgcgcaggg cctcggcgtg tgggccctgg cgctcggcgt cggcgtcctc
     4201 ggctccctcg tcgaggacga cctcgcccgt atccgccccg ccctcacggc cgtccccgcg
     4261 gtggccctcg cgaccgccgt cgtcctcgcc gtccacgccc ggaccgtcga ctggacctcg
     4321 ggccccggca tctccctcct cgccctcgtc gcgggcctgc tcacgaccgg cgtctcgggc
     4381 cgcctcctcc tgacgaaggc gggcgccgcc ggcgaggacg ggaaggagcc ggcctccgcg
     4441 gctgttcggc gcaaggagtg atcaccgcga tgccgcacag aggggcgagg cggtgacggg
     4501 gccgttcaac gaggagagac ccaagccgtt gcgaggcccg ggcggtcgaa aagccgtgga
     4561 gccagggggc cgttgggcgt gatgatggcg ggatgaccca gcacacgcag cccgtggacg
     4621 ccctgatcgt cgtggacgtg cagtcggcct tcgtcgtcgg tgacggggcc gtccccgcgg
     4681 ccgaccggct cgtcgaccgg acgacggacc tgatcgcccg ggcgcggaag gacggggcgc
     4741 tcgtcgtcca cctccagaac gacgggccgc ccggatccga ggacgagccc cacacgcccg
     4801 gctgggaact ccaccacccc gtcgagccgg gcccctcgga gttcgtgatc cgcaagcctc
     4861 aggacgacgg cttccacgag accccactgg gcggcgtact caccgacgcg ggggtcacgg
     4921 ccgtcgccgt ctgcggcgtg atgtccgaga tgtgcgtgca ggcgacggcc cgtacggccc
     4981 tggcgcgcgg ctaccgcgtc gtcgtgccgt acgacgccca cgcgacgcag gactgcccgg
     5041 cggtaccggg cgtccacgag gtcgtgccgg ccgcgacggt ctcccgggtc gcggcgtacg
     5101 ccctcgggag cgacgcggag gttaccgtat ccgccgccga cgtcaccttc acggcccccg
     5161 ccgcgtcccc ggccacgggc gccgcacccg acctccggta accgtggaag cgcgccacga
     5221 gacgtcccgg gacgacgccg agcggaccgt ccgtacgcgt atccgctctg tgagatcggc
     5281 gattgcataa aactgcaatt cattacatcc tggtccggcc cccacgcctc cgcacccgtc
     5341 accatggccg tacgacaggg aagacgacgc gcatgaccat cgaatggcgt tacacggtcc
     5401 agcaggagct gggcgtgctg tccctggccg ggttcctcgg cggcgacgcg ctcggccggt
     5461 tcaccggggc cgtgggctgg gcggtggcac gcggtacggg accggtcgtc ctcgacctga
     5521 gccggctgcg cggctggtcc gcgggcgggc agcacgccgt cgcggaggcg gcccaccggc
     5581 tgcgcgccgc gggccggagc ctcgaactcg ccgcgattcc cgccgacggc tccctcgtcc
     5641 ccgccggcga aggcccggcc atccccgtcc actgcgactt ggacgcggcg ttcgccgccc
     5701 acctcgacgc cggcgcggag cagcgcgcct ggcgcagcga cgcgtggccg agcgagtgag
     5761 ccccgtccgg caccccgtcc ggcattccgt ccggtcctcc gcccggcact ccgtccggcc
     5821 cgagtccgga gatcggtaag cctcgcgccc cggaaggcgc gaggatgggg gcatggtgca
     5881 gagtgctggt tcgacgcgcg atggcggggt gggggcgatg gcggcgccgc tctaccagtt
     5941 gaaggcggag ttcttcaaaa cgctgggaca ccccgtccgg atccgtgtcc tggagctgct
     6001 gagccagcgc gagcacgcgg tcgccgagat gctgcgcgac accggcgtcg aagcggcgta
     6061 cctctcccag cagttggccg tgctgcgccg ggcgaacctc gtcgtcgccc ggcgcgaggg
     6121 cgtggccgtg cactacacgc tgaccagccc gcgggtggcc gaactgctgc tggtggcccg
     6181 ctcgatcctg tccggcgtcc acgcggggca ggcggaaccg ctcgccgacc tccggtcgcg
     6241 ctcgtcctcc accccgtagg gcaccggggt cgggtcttcg ccggtcctca ctccccgggc
     6301 ttcgattcct cctccttctc cggctggatg cccgcgagca ggttgaaggc cccggtcagc
     6361 aggttgagcg tgaccacccc gaccacctcc gcgatcaccc ggtcgctcca gccgtgcgcc
     6421 cgtacctccg cgacgtcgtc gtcggacagg gagcccggct cggcgaggac cttgagtgcg
     6481 aggccgatga gcgcggcctc gcgaggatcg gtcgacgtgc cctggcgggc cagtgcgatg
     6541 tcggtatcgc tcaggcccgc cgcgcgcccg gccgagacgt gggcctcgcg gcacgtgccg
     6601 cagccgatcc actcctgcac ggcgagcgac agcttctcgc tgagggcgcg ggggatcttc
     6661 acccgcttca tggcccggga caggctcaga tagccgtcga gcagcgccgg cgagtgcgcc
     6721 atggtcgaca ccatctcgcc caccgaaccg tggcgttcga cgatgtcgcc gagcacctcg
     6781 cgtgcccggc ccggagcctg ctcgggggtg agcgcggtca gtcttctcgt ggtcacggag
     6841 cctcctcgtt atacccgcgg ggggtataac gagggggagg gtgcacgagt tcccggggtg
     6901 tcaggagtgc agggagggtc gacaggacag cgtcaggcgg gaggggccgt ggaacaccca
     6961 gtcgggggcg tactccacct ccaccccggg ccgggctccg ggggcgagcg cgggcagccg
     7021 gtcgagcagc acaccgagac cgatctcggc ctccgcgcgc gcgagcgccg cccccgcgca
     7081 gtagtggata cccagaccga aggcgcagtg gcggccgctg tcccggtgga tgtcgaggac
     7141 ctcggggtcc gggaagcggt ccgggtcccg atgggccgag cccaggacca actgcaggcg
     7201 gtcgccccgg cggacggtcc ggcccgccag ctccgtgtcc cggtgcgccc accgcgtcac
     7261 catctgcacc ggcgggtcgt ggcgcaggaa ctcgtccacg gcgttcggca acagcccggg
     7321 atcggcgcgg agttcgtccc tcacctccgg ccggtcgagc agcgcgagca ctgccttgcc
     7381 gatcagcccc gtcgtcgtct cgtgcccggc ggtcagcagg tgcgtgcagg tcgccgccag
     7441 ctccgatccg ctgagggacg ggtcctcggc ccccgcccgc gccagcgccg acaggaggtc
     7501 gccgcggtcc tcggtacgcc gtgccgccag ctcccggtgg aagtacccgt ccagctcggc
     7561 cgccgcccgc tcggccccgt ccagcgcggc cggtgtccgg tcgccccggg tcccgcccgc
     7621 ctgttgcagc gccagcgcct gctcgcggaa ccacggccac cgctcggcct ccaccccgag
     7681 cagcccgccg atgaccagca gcgggtacgg ggccgcgaac ccctcgacga gctccaccac
     7741 cggccgccgc gcgagcggcg cgacgagctc ctcggcgatc tcccgtacac gcggccgcag
     7801 cgccgccacc gcggcggccc cgagcggcgg cgtgacgcgc gcccgcaacc gcgtgtgccg
     7861 gggcgggtcg aggaagacga gccagttctc gacgacccgc cgcagcgtga cgtagccgtc
     7921 agggaccggc gccgaacgcg ccgtcagcgg ggacgtccgg ccgaagctcc gccccgccag
     7981 gacgtgcgcc acctccgcgt gcccgaagag gtaccaggtc gtgggcgccg ccccaccgtg
     8041 cccgccccgc acggcgtgca ccgggtccgt ctcgcggtag cgccggtaga ccgggtacgg
     8101 gtcggccagg tcgagccgcg ccgggtcgaa gggctccggg ggctccggcg gcccgcccga
     8161 gaccgtaccg ggccggcccg tccgcccgct catccgcccg ccccgcgcac caagtcggcg
     8221 atccgcagcg gatcggccgg cggggcggcc ccgcgccacg ccacgtgccc gtccgggcgc
     8281 accaggacga acggccgctc gtaccgccgg gccacctccg cgtcgcggca gtgccgtacg
     8341 cggaggggga cccggcgatc ggcgaacgcc cggacgagcc cgtcgacagt gccgcccccg
     8401 tccccgtaac cgtccccgaa gcagagcagg acgaactccc cgccgaacag gtcgagcgtc
     8461 gaccggcccg gtccgagcca cgcgtgcgga gcccgtacac cgggaagcgt cgtacggttc
     8521 cagaccggcc cgtcggaccc ggcaggcgct acggtcccgc cagacccgcc agacccgcca
     8581 gacccgccag acccgccaga cccgccagac ccgnnnnnnn nnnnacccgc cagacccgcc
     8641 agacccgcca gacccgccag acccgccaga cccgccagac ccgccagacc cgccagaccc
     8701 gccagacccg cccgccggaa ccgccccgtc cttctcgtcc gtgatcgccg gagaggcgta
     8761 ccggtacgcg aagtgcaggt cgggcgcgtc gaattccctg agcggatcgg agtccgcgat
     8821 ctcccggccc agtgcggcgc gggcccgttc cccctcctcc gtgtcgtcgc gcagcgcggc
     8881 ggagagccgg cggtcgacgg tccgccggag gttgcggtgg ctctcctcca ggctgttgac
     8941 ggcgacgggc cgccgttcgc tctcgtacgt gtcgagcagc ccggcccccg cccagcccgc
     9001 aagctccgcc gccagcttcc atcccaggtc ggccgcgtcg cccacgcccg tcgcgagacc
     9061 gaacccgccc gagggcgaca gcgtgtgcgc cgcgtccccg gcgaggaaga cccggccgtc
     9121 gcggtaccgc gaggccaccc ggtgggtcag gtgccaggtg gtgtccgaca gcacctcgac
     9181 cggcacgtcg agcacaagcg cccgccgtac cacccgctcg gcgtcggcgg gcccggccgg
     9241 acacgtcagc cggtacagct cccggccgtc catcgcccgc agcggatagc gcagcccgcc
     9301 gggctccgtg acgaaatgga ccagcgccgc gcgcggcccg agcagggcgc cgagcccggg
     9361 gcaccggaag aggatgttgc gcagggtgcg ggtccggtgc cgctcgggcg cgtcgatccc
     9421 gcaggccttg cgcacgggag aggaggcccc gtcgcagccc accacgtacc gggcgtgcac
     9481 cgtcgtccgt accccctccc cgtccacgag cgccgcgccg acccggtccg gcttccggtc
     9541 gagctcgacc aggcgggtgc cgagccggac cggtcccaac ggccggactc ccaggcgctc
     9601 ggtgagcagg ggcgccagcc agtgctgcgg gcagatcgcc tcgggctccg gcgtgtacgc
     9661 gggcgggggc cggtcaccgg ccgtgccgag ccgcagccgg tgcagctcgt aggcgccgac
     9721 ggccgtcacc cacgcgacgt ccagggtgtg gtccgccggc cagcccgcgc cgcggatcgc
     9781 gtcggcgacg ccccagcgcc ggaacgcctc catggcgcgc gggccgacgg tggagacctt
     9841 cgggtgcgcg acccggccgt ccccggcctc caccaggacg aagtccacgc cccggtgggt
     9901 gagatcgagg gcgagcgcga gccccacggg cccgccgccc acgatcagca cctcggtctc
     9961 ctcggtcctc cgacgggtcc tgccgttgtc cgacacggtc tcagctcctc ccctcgtgtg
    10021 cgaagcgctc cgcgtaccag gtcatcagct ccggcacgcg ctccggcacc ccctcgcact
    10081 cccgggccat ggccgcgaga tgccggaagc gcatcgcgaa cccgcgccgg gccacgtcgg
    10141 ggcgcgcgat gtacgcgggc ggctcctcca gctcgaagga cggccccgcc gtccgccccc
    10201 gccaccccga ctccagcggc atcacctgct cggcgagcgg gcgcatcatc cccgtcatca
    10261 cgtcgatggc ggcgttcatc agcttcgagc ggcgcaggct cgcgtccggg ctctccccga
    10321 agtgctgcac gatcagctgg agcatcatga agtagcagcg gttgaagagc cgcatcacct
    10381 gccgggcgtg cggatcgctg accgccgccc gcccggggtg cccgggggcg agcgtcggat
    10441 tgcgcaggct cgggtacgcc gggtgccacg gcgccccctc cccgtgcggc ccgtcggcgc
    10501 gctctgtcat gagcagctcg gcgaggcgga cgaacgtctc gtggtgcgac tcggagccgg
    10561 ccttctccgt gtcgaggacg ccgccctcgc cctgctccgt cacgaagtcg acggcgaaga
    10621 gcgcgctcga caggtcgtcc acctccaact ggtagtccgg atgcacggcg ttgaccgccc
    10681 cgccgatgaa gaggtggtgc tcgcccccgc cgcgcccgcg gtcgaccggg aagaggtcgg
    10741 ggacccggat caggccctcc cggatgcccg cgtacagctc gctcggcgag ccgaacgggc
    10801 ccggcccgtc cgtgcgcccg gtgccgcccg cgagccgctc gggccgctcg atggcgatga
    10861 accgctggag gctgcccagg tgcagcggtt cgagcgcgaa gtccagcggc agcggcagcc
    10921 tgcccggggt gccgaagtcg atctccgggg cgtggaacgg ctcgcccatc gccatcagga
    10981 tgttgttgac gaccaggaag tgcatcatct cctcccgggc cacgtcgaag aggctgtctc
    11041 tgacgccctt ggccagggtc tccccgccgt ccccgcaggc cagccgcagc tggcgcggag
    11101 tccacacccc gctgcggacg tactcgaaac cggtgccgtg cgtcggcacc gagtaccccg
    11161 cgtacaggta ctggagcgag gtggcgagct cgaccgtgac ggcctgccag agcgccgacc
    11221 gcagctgggc ccgtgtggtg atctgcggat acgagcggac cggtgagggc acggcggccg
    11281 ggggtacggc cgccgccgcg ctctgcgcgc gcaggtactt caggagcagc cgcgccttgg
    11341 gcagggacag gtcacgggtc ggcggcatgt agtacgtccg gtccttgttc gccggatcgc
    11401 acatctgcca gatgagcttc gcgtacgtct ccaccttgca gcggtccgcc aggctgaaca
    11461 cctcgtcgcg catgaacggg aacagctgct cgtagtacgc gaacacctcg cggtgcagca
    11521 gctcgaaggt gacgtcctgc tggagcaccg cgtccagctg ccagtcgtcg ggcaggacgc
    11581 ggacggcggc ggagcccgcc cagggccaga agccgagtgc gtcgtcgtgg tcgtagcagg
    11641 cctcagcgga gcccggggcg gccggatcgt ggggcggcag ctcctcggga cccgccgcga
    11701 gcagcagccg tgccgtgccg gcccgcgccc cggagacggt gaaccagccg cgcccgtgcg
    11761 cgtccgtggc cagtccgcac caggacgatc ccgccccgcc gggcccttcc tcggcgagcg
    11821 gcttctcccc ggccgtcctg ccggcccgca gccggacgat ctcgacgtcc ccgcagcggg
    11881 ccgccgcatc cgaggccacc ggatccaagg ggagggcccg ggggttggcg aactgccgga
    11941 cgacgacccc gtcgagcgcg gccggaacac cccgcaggaa ggtccgcacg ggcacctcga
    12001 ccgcgtgctc ctcaccgcgc tcggggtccg gatgctccag gatcaggcag gcctcgtcgg
    12061 tgaggacgac ggcctcgcgc tcccgcagca acaccgcgcg cccgtccccg ccgtccgccg
    12121 ccgggcgcac cagcaccagc ccttcctccg cggcacgccg gaccccctcc gccgacccgg
    12181 ccggcacggt caccaccgcg cctccctccg ccgctccggc cggcagcacg gcgaccggca
    12241 ggtccgagcg ggcggtccgc agctccaggg cgggtccccc gtcccgtacc gccgcaccgg
    12301 tggcgtcgag gcggtgcgcg aagggccagt tgaacgccac cgagtccggg gagaccctca
    12361 cggtgcacgg ccccggcgtc ccgtcggcgt gggattccct cccgtgcggg acgagcaacc
    12421 gccccgccgg atgcgtgcgc ggctcgtccg gccgccacgg cgcgacggtg ccccgcagcc
    12481 gccacacccc gggcgcgtcc accggctccc gtacgccctc cgggggcgcg gccggccgct
    12541 ccagtacgaa ctggacgacg atcccgccgc cctcgcactc ctccacggcc gcccgcaggg
    12601 cgcggacggc gggggagtcc gccgccccgg ccggccagtc gagcccctca ccggcaccga
    12661 tcgcgaactg gtgcagcgtg cggcgcaccg gcgtgaaacc gtgccaacgg ggcggcatga
    12721 aaccgcccac gtccccgacg cacagatagc ccgcgtcgtg cgagcgaccc tcgcgcccga
    12781 aggcgaaccg gccgcccatc agggtcgtcg tccacgcgga ggcgggatcg acgtcgaaga
    12841 cccgggcccg gttcaccgtc gtgccgagat acgggttgta gtgcccccac aggtccacgg
    12901 cccgcccgac gaccggatcg gccgtctcga cggcgccgtc cgcccgctcc accccggtca
    12961 cccgggcgtc caggacgaga tggccgttcc cggagaagtg cccgccgcgc gcgccgtgct
    13021 ccgccaggtg ctcgtggaag gcctcggcgg gcccgtcctc cccgaacggg cccacggccg
    13081 acggacgttc ggaaccaccg cccgcacccc gcagggccgt gttgcgcgcg aggtccacca
    13141 ggccgccgtt cggccccgtg ggcagccgcg tcacggccgt accgccgaag tgcagacggg
    13201 gcaggtcgaa cacgctcatg ccgcctccag tccggcccgc ggggccacgc cccggcccgg
    13261 cgcgtgccgg gcgatgaggt ccacggcctc cagggccgac tcgaccgccc cctcgatcca
    13321 cgcgggctcg gtcgcgcagt gctccccggc gaagaacatc cggcgctgcg gccgcacggc
    13381 ccgccgccgc tgctcctcgc acgcggcggc gtcctggccc caccggatgg tgcagccgcc
    13441 ctccgtccac ggatgctcgc cccacgcgag gctggcgacg ccccgcacca tcccgcgccg
    13501 cagcagctgc ggatgcatcc ggcccagctc ctcgacgacc gtccggtgcc gcagcggggg
    13561 aggcatccgg ccgaggtggt cggcgtcctc gccgatcgtg taactggcga gcagggccgc
    13621 gccctgggcc ggatcggtgg acccgccggt cccggccccg tcggccgccg ccggcggata
    13681 gtacgtctgc cggatgcggc ccccgctgaa ggaggcgccg ccccggatcc cctcgcgctc
    13741 ccagaacggc tcgcggcagt gcaccgccac cttggtcgcc gggcagtagt ccacctcccg
    13801 cacgaccgcg agcttgtcct cgtcgaaacc ggtcagggtg agcccccgca ggacggagaa
    13861 cggcacggtg cacagcacgt agtcgcagcg ccgcacggcc gcgcccggcc cgcccccgat
    13921 ccgtacgagg acgtggtcgg cggccacctc gaagcccgac acccgctgcc cgagccagat
    13981 gggaccgcgc acgcgcgcgg cgagccgctg cacgagctgg tccatgccgc aggcgagccg
    14041 caccagttcg ggactggtct cagtgaggat gtcgtcgagg aaaccgttca ggcgcgtccc
    14101 gcagccggcc cggatccccg ggtgcgcggc gaagagaccg tgcacgtcga tccggtcctt
    14161 ggcgtggccg aggaggtgcg gggacaagtc gacgtcctcg acgaggtcga ggaggttgcg
    14221 ggcgaggtcg gcgcggagcc ccgcccgcag ccccggcggg gcgaccgcgt cgaccacggc
    14281 cgcgagccac gcgccgaaca ccacggtctc ctcgcggtag tcggcgccgg gcagcgaggc
    14341 gcggacgtcg gcgatcagcg cgcggggcgc gtcccgcagc cggacgtggc cggtgctggt
    14401 cgccaggtag gcgttctcct cggacagcag ggtggtgaac gggcggacct ggtcggcgag
    14461 gccgaggtgc tcgacgtacc gcatcgtgcg gtggtgcgcg gtcgggatgc gcatcgcgcc
    14521 gagctccacg aaaggggcgc cctcggacgc gccgaaccgg tgggtgtgga cgcggccccc
    14581 cagcctgcgg ctgccctcga tgacctcgac gcggaacccg agccgctcca gctcgtacgc
    14641 ggcgaccaga cccgccatcc ccgcgcccac gacactgacc gtgctgttgg cgcgggtgcg
    14701 gcggcgggcg cggggcagga gctgctgtac gtgaccgggc cgcgtgacgg cggcgggctg
    14761 cgtcacggtc tgcgtgacgg ttgaggtctg catgacggtc cgactccccc tcgaatcagc
    14821 gaatcagcga atcagcgaat caacgaatca gtgcgtgcgg tgcgggtggt gctcctcgga
    14881 ccgccggacg ggcatccggg cctcggcggc gagcgccacg aggtaggagc ggagcagagc
    14941 gggacggtcc agcggagcga ccaggccgac gtatccgtcg ggccggacga gccgcaggtc
    15001 gtcggggtga ccgagccgcc gggcctcggc gccgtcccag ggcgtcaccg ggaggacgcg
    15061 gaccggggcc gggaacccgt cgcaggtctc ccgcagggcg tcgagcacgc cggcgtcggc
    15121 ccgttcggcg tgcaggacga gcgtccaccg ctcgtacccg agcagcgtgt gcagccggac
    15181 tgccgcgacg ctcgcgacgg actggacggc ggtcccggtg ccgcactcgg cggagccggt
    15241 ggcgagggcg acgtccggca tccggtctcc cgcgcgcgga ccgccggggc gaccgtggcg
    15301 gccgggccgg tgccgggaca gcgcgccgtc ccggtggttc cggctcaggt cgctcagccg
    15361 caggtccagc cggcgctgga tgccgcgccg ggcgagggcc gcgggcacgg tcgccgtgaa
    15421 cacccggtag ccgagcggcg ggagaggcag ctccatgaag ttgaaccgca tctcgcggat
    15481 gtaccgcacc gcgagcagcc gctgctcgtc gctgtacgtg tcgaggagct cctcgccggc
    15541 ctgcccgtgg tgcacggcgg ccagcttcca ggcgaggttg tgggcgccga ggacgccgac
    15601 gttcattccg tggccgccga ccggcgccca ggcgtgcgcc gcgtccccgg cgagcagccc
    15661 gcgccccgag cggagccggg cggcgacccg gtcgctgaag cgggcgcggt tgagccagag
    15721 gtgctcggtg gcctccaggc gcagtccggg catcccggcg gtctccgcga ccaggtcccg
    15781 gagctcgccg atggtgggtg cggtggtgag ggtgggatcg gggtcgtcgc ggaagcagaa
    15841 gaaacggaag cccccgccgg gcagcgggaa gacgagcagg gagcggtgcg gggccaggaa
    15901 gatgtggccc cggcccggct cctcgcccag ctgccaggtc ggttgggcgt tgccctggac
    15961 gacctggagg cccgtgcggc ggcgcccctc gaaggggatg cccagccggt ccctgacgac
    16021 gctggcggtg ccctcgcagc cgacgatcca cggagcgacc gcggactcca ccgtgccgtc
    16081 ctcgtgccgc agggtgaact cggcccggtc gtcgtgcacc ttgacgtccg tcagctccgt
    16141 gttccactcg acccgggtgc cgagccgggc cagttcctcg gagaggaggc gctcgatgtc
    16201 gtgctgttcg atgttgaggg gccgggcgtg ggccgaccgc gcccagccgg tggtgagttc
    16261 gccgagggcc cggtcgcggg cgtggatggt caccacctcc agctccaccc cgtgacgccg
    16321 gagcgtctcg ccgaccccca gggagtcgag cgcctcccgg gcccgcgccc acagcaccag
    16381 ggcccgggcc tcgcgcttgg tcgcgggcgc cttgtcgacg atccggacgc ggagcccgag
    16441 ccggcgcagg ccgatggcga gggtgaggcc gaccggcccc gccccgacca cgcacacgtc
    16501 cacgtcgccg gccgagccct tggcaccgtc cccgccggcg tctccgtccc tgcctgtgtc
    16561 caaccgggcc accccccgct cctcgctcac ctttcccggt gttcagcgtg cttgcggaag
    16621 atcaccttca acagggcgtg tacgggggcg cggggatcac tgcgacctgg gggtattact
    16681 acctgtgcat catctggtcc gtttgagtga cgagcggtgg aattcggccg cccgcaccgc
    16741 tccggagccg tggcccgccc gtggcgggcc tccgctccct ggcctgatca ggacccttcg
    16801 acgcgggttc gtcctccccg agttgacaga agtacgcctc gacgaacggg aaccggaagg
    16861 tgggggtggc cctcccggga agaggcgcgt ggccagttct ggacaggcgt cacccggccg
    16921 ccgcacgctc cgcgcactcc aggagcgtgg gaagggccgc ctccagggcc gcggtcccgt
    16981 gcgcgtacgg cagtcggagc cggtcccgga agccgtccac cggggagaac gccgagcccg
    17041 ggacgacgga gacgccgcgg cgccgcgcca gttgggcgag ggtctcggtg tcggcacccg
    17101 ggacgcgcac ccagagggcg gcgccgcccg ccggccgggt ccactcccag tgcggcgccc
    17161 cggagcgcag cagcgcctcg gccgtgtccc gttgggcccg cagctcggcc ctgcgccggg
    17221 cccgcgcctc gggcagccgg tcgagcaggc ggacggccac cagctggtcc atgaccgagc
    17281 aggacaggtc gaccgaggtc ttgatcttcg cgagccgggc caccacctgg ggggaggagc
    17341 ggacccagcc cacccgcagg ccgccccaga acagcttcga gagcgtgccc acggtcaccg
    17401 tcgacgccat gggcagcccg gcgaccagcg gttccggagc gcccccgtcg tctcccggcc
    17461 ctccgctcgc ggccttctcc cccaccccga gggagagttc ggcgcaggcc gtgtcctcga
    17521 ccgtgaacag ctccaggtcc cccaggaccc gccgccactc ccggcgcgcc gcgccgtcca
    17581 gcgtccgccc cgtcgggttg tgcacggtcg gctggaggta caccagccgg ggccggccat
    17641 gggcgctcag ccgtcgcacg gccgccgcgc ccgagccgtc ccctccgccg tccccgtccg
    17701 tgccgaccgg taccagccgg gcgccccgcg cccgcagcgc ctccaaggcg ccccggtacg
    17761 tggggtcctc cacgacgacc gtgtcgcccg gctccaccaa agcctgcgcc acgagccaca
    17821 ccgcctgctg cgaccccgcg gtcaccagga tctgcccggc ctccgtcggc acgccggccg
    17881 cccggtagta cgcggcgatg ccctcccgca acgccgggat gccgtacggg tggtagccgt
    17941 cggccacgag cagcccgccg aggtcgccgg aggtcagcgc ccccaccgcc tcgccgaccg
    18001 cgccgagccc cgggagcgcc ccgctcgaca ggtccgcgat gcccgccgtc cccgtccccg
    18061 tacgggcgtc gaagctcacc agccgcccct cggcgacgta ccggtcgagc gcccccgagg
    18121 cccgcagccg cgagccgctg ccgcgcacgc tctccagcca cccctcggcc tccaggaggc
    18181 cgtacgcgga ggtgaccgtg gaccggctga cggccaggac cagcgccagt tcgcgctgcg
    18241 agggcagcac ggtccccgcc ggtacgtcgc cgcgctcggc cagctcccgc agcgcgtccg
    18301 ccagtcggcg tggcagcggt cccgcgccct ccgaggacca gccggtgagg agtcgggaca
    18361 aacgggtcga agcaatcctg gccatggcac ccatagtgcg ccacggcgca ggccaatccg
    18421 gccggactgg tcgttgtcgc cgcaggtggc gcgacggagg atcgacgaga acgggaccgg
    18481 accgcggtac cggacgcggg accgggagaa gggtgggggc atggcgaccg tcgtgctggt
    18541 cgggacgctg gacacgaagg gggaggagta cgcctggctg cgggagcggc tcagggagta
    18601 cggcagcgac gtcctcctcg tcgacaccgg tgtcctgccg ccgcccgcgc acgcgcccgt
    18661 gcccgacgtc tccgccgacg tcgtcgcgcg cgccgccggt cacgacctgg ccaggctgcg
    18721 ggcggcgggc gaccggggcg ccgccgtctc cgcgatggcg cacggcctga cccgcgtcgt
    18781 cctcgacctc taccgcaagg ggaagctgca cgccgtgctc gccgcggccg gcagcggcgg
    18841 ctccgcgatc gccgcccagg cgatgcgggc cctgcccatc ggcgtgccca agatgctcgt
    18901 cagcaccatg gtcggcgggg acgtctcccc gtacgtcgac agcagcgacc tcaccatgat
    18961 gtacagcgtc gtcgacatct ccggcctcaa cgccgtctcc tgccaggtcc tcggcaacgc
    19021 cgcggcggcc gccgccggca tggcccgccg gtacgagcgc aaccacgacg aacccgcagg
    19081 ccgggggcgc ccggtcgtcg cggccaccat gttcggcgtg acgaccccgg ccgtcgacgc
    19141 ggcccgcgcc cggctcgccg aactgggcta cgaggtcctc gtcttccacg ccaccggcgc
    19201 gggcggccgg gccgtcgaga agctcgccag ggacggcatg ctcgacggcg tgctcgacct
    19261 gacgaccacg gagctcgccg acgagctggt cggcggcgtg ctcagcgcgg gccccacgcg
    19321 gctcaccgcc gccggggtca tgggcatccc gcaggtcgtc gcccccggag ccctcgacat
    19381 ggtcaacttc ggcccggccg cgaccgtgcc ggaacggttc accgagcgcc gactgctcgt
    19441 ccacaacgcg acggtgaccc tcatgcgcac caccgccgcc gagatggccg agctcggcac
    19501 cggaatgggc cgcaagctcc gcacggcgcg cggccccgcc gaggtcttct ggccgctgcg
    19561 cggcatctcc gccgtggaca ccgccgacgg ccccttcgac gaccccgagg ccgaccgggc
    19621 cggtctggac gccctgcgcg cggccgtccg cggcggcgag gtccgcgtcc acgaactcga
    19681 cgcgcacatc aacgacgcct ccttcgcggt cgccatggcc gaccgcctcc accagctgat
    19741 cgccgagaac acccgcggac cgggctactg aacgacctgc ccaccgggtc gccgaacgac
    19801 gtgatgaatc gacgtgacga cccgcgaccc gatgaccggc gacctgatga ccggcgacct
    19861 gatgaccggg ccaccccaca ctccgaggag acatccacag tgaacaccgg atccaccgtc
    19921 agccgtcagg acgtcctcac ccggctgcgc gcccaggtcg ccgcgggccg gccgatcgtc
    19981 ggcgccgggg cgggcaccgg actctccgcc aagtgcgccg aggcaggcgg ggtcgacctg
    20041 ctgatcatct acaactcggg ccgctaccgg atggcgggcc gcggctccct cgcgggcctc
    20101 ctgccgtacg gggacgccaa cgcgatcgtc caggacatgg cccgcgaggt gctgcccgtg
    20161 gtccgcgaca ccccggtcct cgccggggtc tgcggcaccg acccgttccg ccgcatggac
    20221 ctcttcctgg acgagctgaa ggccatgggc ttcgcgggcg tgcagaactt ccccacggtc
    20281 ggcctgtacg acggcacctt ccgcgtcaac ctggaggaga ccggcatggg gtacggcctg
    20341 gaggtcgaca tggtcagggc cgcccacgag cgggacctgc tgaccgcccc gtacgtcttc
    20401 gatccggagc aggccgccga catggccgcg gcgggcgccg acgtcctcgt gccccacgtc
    20461 gggctcacca ccaagggcgc catcggcgcg ggcacggccc tgacgctcga ccaggcggcg
    20521 gcagcggtcc aggagatgca cgacgccgcc aagcgcgtga accccgacat cctggtcctc
    20581 tgccacggcg ggcccatcgc ggagccggag gacgcgcgtt acgtcctgga gcacaccacc
    20641 ggggtcgtcg gcttcttcgg ggcctcgtcg atcgaacggc tgcccacgga acgggccgtg
    20701 accgagcaga cccgcgcctt caaggctctc accctcggct gacggctccc ggcgcggcct
    20761 ccgggcgtcg gccctgtcgg tggcgtggcg tacaactgag agcggggaaa agagcacgac
    20821 cgcacgactg cgcgaccgac gtgcgaccgc acgaggggga ctgtacgtgg acaccatcgc
    20881 ggaccagggg tgcgccgacc gcgcgcccct cgtcgggcga gcccgggaac tggaccggct
    20941 ggacgggctg ctgggctgcc gcacggaggg tgcgggcccg gtggccgtgg acgtcacggg
    21001 cgagcccggc atcggcaaga cccgtctcct gacggagttc gggatacggg ccaggggccg
    21061 cggggcgacc gtcctgcggg gcagggccgg gaccgccgaa gggcgcgccg gcactccctt
    21121 ccaggccgtc ctggacgcgt tcgccgacct cgaccaccgg gagcgcgcca ccacgccggc
    21181 cctggccgaa ctcgcccggc tcgtcgagca cgacgggcgt gacgcgtcgg gcgtgcgtga
    21241 cgggcgcaac gggcatgact cgtcgggccc gcgtgacggg cgtgaggtgc gggacgggca
    21301 tgactcgtcg ggcccgcgtg acgtgtgtga ggtgcgggac gtggaggacg agcgcgtgcg
    21361 gcggatcggc gccgcgctcg gccgggtgcc cgcgcccggg ctcgtgctcc tcctcgacga
    21421 cctccaccgt gccgacccgg ccaccgtcgc cctcgtcgac cacctcctcc ggcaccccct
    21481 gcgcgccccc gtcctggtcg tcgtggcccg acgggagcgc cagacgccgc ccgccctcgc
    21541 ctcctccctc gcccgggccg ccgactccgg cgcgctcgcc cggctggacc tcggaccgct
    21601 ggcggcggag gactgcgccg aggccctcgc ccccggggcg ccgccggaca cggtgagcga
    21661 gctgtacgcg gccagcggcg gcaacccgct ctacttccgc gcgctcgccc acacccgtac
    21721 accgcacggc cgcgcgcccg gcaccggccc ggtggccgtc ctcctcgacg aactgacacc
    21781 gctctgcggg gtggagcggg cgatcgtcga ggcgatcgcc gtgctcgacg ggagggccac
    21841 ctccgaactg gtcgcggccg tggcggcgcc cggtcgaggc gagggagcca cggagtacgg
    21901 ggcggacagg gagcagggcc ggggcggtca ggagacgatc gacgccgccc tgcgcgcgct
    21961 ggcccgccgc gacctcgtcc ggaccgacga ggcaggccgt accctcggcc tgcgccatcc
    22021 ggccctcccg gaactggtcc ggggcgcgct cgacccgtgg cgccgccgcg aactgcaccg
    22081 ccgggcggag gccgcgctgg cccggtccgg cgcacccgcg agcgcgcggg ccccgcacct
    22141 cgtgggcgcg gcgaccggtc cggatgccgc gaccgcggcc gtactcgtcg aagccgccga
    22201 gcggaccggg accgtcgacc ccgcgcgcgc cgcccactgg ctcgcggcgg ccctcgacca
    22261 cctccccgac acggccgagc acctcgccca ccggctcgaa ctgacgctcc gccgagccca
    22321 ggcactcggc tcggccggcc gcgtcgccga gagccgggac ctcctccacc gactcatcga
    22381 cacgtgccgc ccgggctccg gccgcggccc gtgcgacacc cccggcggcc acccccagga
    22441 cacggcgggg atccggacct ccgccgtcct cctgtgcgcg ttcatggagc gccacctggg
    22501 ccgctacccc gaagcggacg ccctgctccg ccgcgagctg gagcgcaacc ccgacccccg
    22561 ggcgggcctg cggaccgggc tcgtcgtcga gtggggcgcc cgcgccctct tcgccacccg
    22621 ctaccccgag gtccgcgagg aggtcgaccg gaccctcggc gaggcgcggc tccgccacga
    22681 cgaggcgcag accgcggagg tcctgacgct ctcggccctc ggcgaggcct acgagggcgg
    22741 gaccaccaag gcccgcgccc gcgcgacgga ggccgcggcc ctcaccgacg ccctcacgga
    22801 cggcgaactg gccgaccacg tcgagtcgct ggtgcgcctg agctggaccg aggccttcct
    22861 ggaggagtac gggacggccg agcgtcacac cacgcggggc atcgcggtcg tccgccgcgc
    22921 cgggcggccc ttcgcgctct cgcagctcct cctctgctcg gcgtacgtcc acttcctcac
    22981 gggcagggtc ggcgccgcgc tcgacctggc ggaggagtcc ctcaccgtcg cccaccccct
    23041 gggcggcgcc gagctcctcg gcttcagccg ggcgatgcgc gccaccgtcc tcctccacgc
    23101 ccggccgctc ggcgaccccg aggcactggc cgccgcggag gaggccgcgg ccaccgtggg
    23161 caccgcccag agctggtggg ccacgcaggc ccgctgcatg ctcgcccaca acgtcccgg
//
