LOCUS       NZ_LMEQ01000031        22569 bp    DNA     linear   CON 07-JUN-2024
DEFINITION  Streptomyces sp. Root1310 contig_5, whole genome shotgun sequence.
ACCESSION   NZ_LMEQ01000031
VERSION     NZ_LMEQ01000031.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root1310
  ORGANISM  Streptomyces sp. Root1310
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 600179)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 600179)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140604
            Assembly Name                     :: Root1310
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001426425.1-RS_2024_06_07
            Annotation Date                   :: 06/07/2024 02:14:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,470
            CDSs (total)                      :: 8,385
            Genes (coding)                    :: 8,123
            CDSs (with protein)               :: 8,123
            Genes (RNA)                       :: 85
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 262
            CDSs (without protein)            :: 262
            Pseudo Genes (ambiguous residues) :: 0 of 262
            Pseudo Genes (frameshifted)       :: 98 of 262
            Pseudo Genes (incomplete)         :: 219 of 262
            Pseudo Genes (internal stop)      :: 20 of 262
            Pseudo Genes (multiple problems)  :: 64 of 262
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:32:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 499966
            Orig. end                         :: 522535
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMEQ01000031.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22569
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="4"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..22569
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22569
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12569](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12569
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     gene            complement(368..826)
                     /locus_tag="ASD48_RS42760"
     CDS             complement(368..826)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662157.1"
                     /locus_tag="ASD48_RS42760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_199876074.1"
                     /transl_table=11
                     /translation="MAMPPVPPQPPGPPGDMPPPGGFGPPRSGYGPDDGTGGGGWSPPP
                     SGPPGGSGRRRNPLFVVLALLVTAGAVVAVVLMRGDDSPADEPDVGNSTGATPAPSFSL
                     PVELPSGLPTELPSRLPTRLPSRLPTALPSDLPSDLESLLPSLEELLP"
     gene            complement(1091..2257)
                     /gene="xylA"
                     /locus_tag="ASD48_RS32925"
                     /old_locus_tag="ASD48_23340"
     CDS             complement(1091..2257)
                     /EC_number="5.3.1.5"
                     /GO_function="GO:0009045 - xylose isomerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="xylA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020118437.1"
                     /locus_tag="ASD48_RS32925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23340"
                     /product="xylose isomerase"
                     /protein_id="WP_057605458.1"
                     /transl_table=11
                     /translation="MSYQPTPDDRFTFGLWTVGWQGRDPFGDATRRALDPVESVQRLAE
                     LGAYGVTFHDDDLIPFGSSESEREEHIKRFRQALDTTGMTVPMATTNLFTHPVFKDGAF
                     TANDRDVRRYALRKTIRNIDLAVELGAKIYVAWGGREGAESGAAKDVRVALDRMKEAFD
                     LLGEYVTSQGYDLKFAIEPKPNEPRGDILLPTVGHALAFIERLERPELYGVNPEVGHEQ
                     MAGLNFPHGIAQALWADKLFHIDLNGQSGIKYDQDLRFGAGDLRSAFWLVDLLESAGYA
                     GPKHFDFKPPRTEDLDGVWASAAGCMRNYLILKERALAFRGDPEVQEALRASRLDELAQ
                     ATAPDGLDSLLADRTAFEDFDAETAAARGMAFEHLDQLAMDHLLGARG"
     misc_feature    2315..2327
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.37"
                     /tool="antismash"
     misc_feature    2332..2343
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            2398..3843
                     /gene="xylB"
                     /locus_tag="ASD48_RS32930"
                     /old_locus_tag="ASD48_23345"
     CDS             2398..3843
                     /EC_number="2.7.1.17"
                     /GO_function="GO:0004856 - D-xylulokinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_process="GO:0005997 - xylulose metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0042732 - D-xylose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="xylB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1210: glycerol kinase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004003033.1"
                     /locus_tag="ASD48_RS32930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23345"
                     /product="xylulokinase"
                     /protein_id="WP_057605459.1"
                     /transl_table=11
                     /translation="MSAAEGPLVVGVDTSTQSTKALVVDAATGQVVASGQAPHTVTSGA
                     GRESDPRQWWDALREALHQCGDAAREAAAVSVGGQQHGLVTLDERGEPVRPALLWNDVR
                     SAPQARRLTEELGGAKFWAERTGSVPAASFTVTKWAWLAEHEPEALRATKAVRLPHDYL
                     TERLTGEGTTDRGDASGTGWWASATESYDAEILAHVGLDPALLPRVVRRGEVAGTVRDS
                     HDLPFAKGTLVAPGTGDNAAAALGLGLLPGTPVLSLGTSGTVYAVAKRRPTDPTGTVAG
                     FADAHGDWLPLACTLNCTLAVDRVAALLGLDREAVEPAADLTLLPYLDGERTPNLPNAS
                     GLLHGLRHDTTAGQLLQAAYDGAVHSLLGALDLVLDEDADRSAPLLLIGGGARGRAWQE
                     TVRRLSGRPVQVPEARELVALGAAAQAAGLLTGEDPAAVARRWNTTRGPVLDAVERDEA
                     TLARIAGVLSDAAPLLDRSTGAH"
     gene            3866..5074
                     /locus_tag="ASD48_RS32935"
                     /old_locus_tag="ASD48_23350"
     CDS             3866..5074
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1108: ROK family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003977660.1"
                     /locus_tag="ASD48_RS32935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23350"
                     /product="ROK family transcriptional regulator"
                     /protein_id="WP_057605460.1"
                     /transl_table=11
                     /translation="MTAPLHEARPTGPGRALPDTQQGMRRRNLARVMHAVRAEGPLSRA
                     AVASRIGLTRAAVSTLVDELIRTGLIEELGPERPGRVGRPGSALAVSGHGPAGIGAEIG
                     VDHLVACAVDLRGEVRARAVRHGTNRGRSPEPVVEELTGLVRQVVAEAEREGLWPAGLA
                     VAVPGLVARDARTVVRAPNLDWQDVDLGALLPGQFPLTVDNEANFGGLAELWLGADTPE
                     NFLHVSAEIGIGAALVVDGSLLRGTRGFAGELGHVPVHPDGPECGCGGRGCLEQYAGEE
                     AVLRAAGLEPGEDRVGLLAGRAADGDPDVRRALREAGTALGIALTGALNLLDPEGVVLG
                     GALAGLAPWLLPSLEAELSRRTAGPARAVSVSRLGPEGPLLGAAHSVVRAVLDDPAAVA
                     ERA"
     misc_feature    5295..5310
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.01"
                     /tool="antismash"
     gene            5480..6079
                     /locus_tag="ASD48_RS32940"
                     /old_locus_tag="ASD48_23355"
     CDS             5480..6079
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125811.1"
                     /locus_tag="ASD48_RS32940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23355"
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="WP_057605461.1"
                     /transl_table=11
                     /translation="MERAKSLPGRRRILKGAALAAVPYVLLPDAPAGARTRSVDYPRAE
                     WQPAAAANRTAANRPLGHPVDRVVIHVTQTLYAKALTVFQNPRKRVSAHYVVRSVDGHV
                     AQCVRESDIAWHSGNWGYNTRSIGIEHEGWVDRPVWFTDALYEGSARLTASVCDRYGIP
                     KDRAHIIGHYEVPGTDHTDPGPNWDWSRYLRLVSRA"
     misc_feature    6227..6239
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.63"
                     /tool="antismash"
     gene            6268..7536
                     /locus_tag="ASD48_RS32945"
                     /old_locus_tag="ASD48_23360"
     CDS             6268..7536
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125810.1"
                     /locus_tag="ASD48_RS32945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23360"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_057605462.1"
                     /transl_table=11
                     /translation="MTDPWVALEPGADPAERVRVLRRAHETFAEAGTVPRPVRSVVADS
                     WRRSARAGVGPDGAASVELTDGDLGSYRSEHPLARVMPLFRELMGTFAADGEHLLAVCD
                     AHGRLLWVEGHAATRRQAGRMNFVPGARWAESAVGTNAPGTAVALDRPVQVFAAEHFIR
                     RVQPWTCAAAPVHDPRTGRVLGAVDITGGDGLAHPHSLAFVQAVARAAEAHLALLAPER
                     PAVDAPRLTVLGRDEARLVTGGRDLRLSRRHSEILVLLARRPEGLTGDELLCALYEDES
                     VPPVTLRAELARLRGVLGPGLLASRPYRLTVACESDVAVVERRLAAGAVTAAATAYTGP
                     PLPSSQAPAVARLRSRLAEGLRAALIARGDPDLLADWAHAPWGEDDLDVWRALAAARPT
                     AAIRARLASLESELTAPTGWPHP"
     gene            7831..9354
                     /locus_tag="ASD48_RS32950"
                     /old_locus_tag="ASD48_23365"
     CDS             7831..9354
                     /EC_number="1.2.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014056340.1"
                     /locus_tag="ASD48_RS32950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23365"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_057605463.1"
                     /sec_met_domain="Aldedh (E-value: 3e-163, bitscore: 538.6,
                     seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRYAAPGTEGAIVSYQTRYDHYIGGAYVPPARGQYFDNPSPVNG
                     ETFTEVARGTEEDVELALDAAHAAAPGWGRTSATERSDILLKIADRMEAHLEPLAVAES
                     WENGKPVRETLAADIPLAIDHFRYFAGAVRAQEGSLSEVDDDTVAYHFHEPLGVVAQII
                     PWNFPILMATWKLAPALAAGNTVVIKPAEQTPASLHYWMSLVADLLPPGVVNIVNGFGP
                     EAGKPLASSPRVAKVAFTGETSTGRLIMQYAAEHLKPVTLELGGKSPNIFFDDVWEKDD
                     DLRDKALEGFTMFALNQGEVCTCPSRGLIQRGNYGDFLQAAVARTELIKPGHPLDTDTM
                     IGAQASGDQLAKILSYIDIGRKEGAKILTGGERAEYDGELKGGYYVQPTIFEGDNRMRI
                     FQEEIFGPVVSVASFDDFDDAVKIANDTSYGLGAGVWTRDINTAYRAGRAIQAGRVWTN
                     CYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTKNLLVSYSPKKLGFF"
     misc_feature    9582..9595
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.99"
                     /tool="antismash"
     gene            9864..9974
                     /locus_tag="ASD48_RS43860"
     CDS             9864..9974
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656044.1"
                     /locus_tag="ASD48_RS43860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="keywimysin-related RiPP"
                     /protein_id="WP_019759430.1"
                     /transl_table=11
                     /translation="MKKAYEAPTLVRLGSFRKETGLLGRSGNDRLILSKN"
     gene            10001..11851
                     /locus_tag="ASD48_RS32955"
                     /old_locus_tag="ASD48_23370"
     CDS             10001..11851
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_057605464.1"
                     /locus_tag="ASD48_RS32955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23370"
                     /product="lasso peptide isopeptide bond-forming cyclase"
                     /protein_id="WP_057605464.1"
                     /sec_met_domain="Asn_synthase (E-value: 2.3e-47, bitscore:
                     157.3, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTELHESAGTGPGDAHFAVFTDRADAAAAARSFALPGSRTLTHAS
                     GRPWLVGHWHDDEVVTGNAGGAALAVVGCCPVTADELRRRAARLRDLTELDALARSLPG
                     SFHLVGALDGQVRVQGTASGLRLVFHAEIDGLRVAATRADTLAAVLGLDPDVEELAVRL
                     LWPAPYPLFETSLWRAVTAVPPQDAVVVTADGRTARHTRWWTPPEPVRPLAEAAPLIRR
                     ALEEAVGARTRQGGVVSCDLSGGLDSTSVCFLADRSPARVVASTWPGRDPADTDLHWAE
                     QAMGHLPDVEHVVWDADASPLVYEDLLGIDDLLDEPTIGVMDRSRVLHHLPGLASRGSR
                     LHLTGIGGDHVAWCSEAYYHRLLRTRPLFAVRQLRGFRALWQWPLGGTAHALADSRSYG
                     KWLADAAGRLRGPLPPSVATGLGWGMAPRLFDWVTPEAEHMARRALHAAAASISPLHPD
                     RGMHSDLEQIRSCTRVIRQWDRMAARAGLPMASPFLDDRVIEACLAVRPSERVTPWTYK
                     PVLGAAMRGIVPEACLRRSTKATASMDASNGLREHRADLLALWEDSRLEELGLVDAAEL
                     RRLARRPASPGLSDAILYSTIAAEVWLRGISGSHTRVPHL"
     gene            11881..12135
                     /locus_tag="ASD48_RS32960"
                     /old_locus_tag="ASD48_23375"
     CDS             11881..12135
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988506.1"
                     /locus_tag="ASD48_RS32960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23375"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_057605465.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 5.9e-24,
                     bitscore: 79.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 4.8e-17, bitscore: 57.1,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLRFGADVSTAETDYGTVLLDERVGAYWELNPTATLVVRTLIDG
                     GEESDAAAALVREFDIDEAQALRDVEALVGQLRSSGLAS"
     aSDomain        11887..12129
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_ASD48_RS32960_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="3.10E-25"
                     /identifier="RREFam002.1"
                     /label="ASD48_RS32960"
                     /locus_tag="ASD48_RS32960"
                     /protein_end="83"
                     /protein_start="2"
                     /score="79.0"
                     /tool="antismash"
                     /translation="LRFGADVSTAETDYGTVLLDERVGAYWELNPTATLVVRTLIDGGE
                     ESDAAAALVREFDIDEAQALRDVEALVGQLRSSGLA"
     gene            12132..12569
                     /locus_tag="ASD48_RS32965"
                     /old_locus_tag="ASD48_23380"
     CDS             12132..12569
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988507.1"
                     /locus_tag="ASD48_RS32965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23380"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_057605466.1"
                     /sec_met_domain="PF13471 (E-value: 1.7e-25, bitscore: 84.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPSALERPTGVPMARRLAAHLVLLPAVALALLPPRRIRTVLGI
                     LRRGAAPATTRHAQNARDAMCAASLHCAGPKGCLPRSLGAALLCRLGGTWPTWCTGVRV
                     VPPFTAHAWIEAEGSPVGEGAPEGYFARLVAVAPLPRPTDR"
     gene            12566..14419
                     /locus_tag="ASD48_RS32970"
                     /old_locus_tag="ASD48_23385"
     CDS             12566..14419
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003988508.1"
                     /locus_tag="ASD48_RS32970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23385"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_057605467.1"
                     /transl_table=11
                     /translation="MTGTTVANGGPARVAEGDKSTRTAVATMYRLTAGHRNAIAVATVL
                     TLMGSALGLAQPLIAKHVVDASGRGQVIWPLLALLGALFVTEAATGAAGRFLLERMGER
                     VVRQVRHGLVGRLLRLEMREYDRQRGGDLISRVTADTTLLREVVSQALVDLVTGSLVAA
                     GAIVLMAWLDPLLLLMVAVTVAAAALVVASLLTGIRGASEHMQDSVGAIAADLERALGA
                     LPMVRVHCAEEREAAGIGARVEAAYGAGVRTAKLASVMSPAVELAVQGSFLIVLVVGGL
                     RVNGHAGSLGDLVAFLLYASYLVLPLSSVFHAVGLIQRGMGAYQRIDQALRLPVEPTAP
                     RIRRVPVPTPAPTGPSDTLEQPALALRDVRFGYAPDRPVLRGVSFAVPHRQHVALVGRS
                     GAGKSTVFALVARFYEPDAGHVLFDGLPAAQLTRDACRRRMAVVDQNAHVVRGTLRDNI
                     VYAVPDATEAEIRRVMELARLDEVVDRLPGGLAAVIGERGSTLSGGERQRVAIARALLA
                     RPSLLLLDEPTSHLDAINESALTTVMKDVAQECALLVIAHRLSTVQHADHIVVLHDGRT
                     AAGGRHEELLAVSALYRELAASQMLRPGGHPGNGDRAGTSG"
     gene            complement(14730..16409)
                     /locus_tag="ASD48_RS32975"
                     /old_locus_tag="ASD48_23390"
     CDS             complement(14730..16409)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642122.1"
                     /locus_tag="ASD48_RS32975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23390"
                     /product="hypothetical protein"
                     /protein_id="WP_242432804.1"
                     /transl_table=11
                     /translation="MPLQSFTLPTPASLEPPASALRRERRSSGAARYRVPLLAIAAVLP
                     LYWGWDALLATDGGDLAAQYAWAGFVGRHPVTPYGLFWFGGVHTVNYSVISPHLMALLG
                     VRAVSVLSGVSATCLLAMLLERTVPRVSLWPGLVGALGLWYNVVLGRTTFALGLAFALA
                     GLLAVADRAPRPARLAAAAFGALFATMGSPVAGLFLLVAGAGYLVTRQYGKCLALTLPP
                     VAVVGLTTLLFPFHGEQPMAAGRMILPVLLSAAVVWASPRKWRVVRAGSALYAAGVVLT
                     WLVPSPIGNNVERLALLFAPAVLLAAALHRRSGATRNGVRRTRMRAMALVTALSVSYLC
                     VTSLMHLRSPDPVPGWVTHTDGVLAALARLGADRGRVELPTDRDHRGATLLGPHVELMR
                     GWNQQLDVERGRLFYEGDLDGPRYHAWLRHWAVGYVVLHDGPPDRSAERETALIKEGQH
                     WLELVWQDRYWKIYRVRDTLPLVSAPAVLQHAGEAGLTLRMPRAGTSTVRIAYSPWLRA
                     EGACVSADGPWTRLTAPRAGVYRLTSDYAAGSVDDGGCRPAG"
     misc_feature    16502..16517
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.23"
                     /tool="antismash"
     misc_feature    16892..16907
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.79"
                     /tool="antismash"
     gene            complement(17069..18040)
                     /locus_tag="ASD48_RS32980"
                     /old_locus_tag="ASD48_23395"
     CDS             complement(17069..18040)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125808.1"
                     /locus_tag="ASD48_RS32980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23395"
                     /product="hypothetical protein"
                     /protein_id="WP_057605468.1"
                     /transl_table=11
                     /translation="MSHRSMKLIMSAVVVAAATLAAAVPADATSTGGPLTHVRVATHFD
                     LSTGQMPENITLLPDGTAAVTFAAGRQVAQVTRRGATRVLATLPAPADGGVGTPVLGFP
                     LATGIAHTADGTLYVLYATGTADLTGLWRLRPGQAPQRIAALPAGGLPNGLALDEHSRQ
                     LYITDSVLGTVWTVPVTGGTPRAWSAAPELASTGFLGANGAKVHGGALWVTNLDRGTVL
                     RIPIRSGNRAGAPQVKASGLAGIDDFAFTGRGDEILAALNGPNTVVRIRTDGTGTTVLD
                     ATDGLQNPTSVALRGKDVYVLSAAYTTAADPNLLRARLGGRP"
     gene            complement(18295..19194)
                     /locus_tag="ASD48_RS32985"
                     /old_locus_tag="ASD48_23400"
     CDS             complement(18295..19194)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125807.1"
                     /locus_tag="ASD48_RS32985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23400"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_057605598.1"
                     /transl_table=11
                     /translation="MNKHGHLADFLQARRSQLRPQDVGLQTYGERRRVPGLRREELAML
                     AGISAPYYTRLEQGQSRNASREVLDAVASALRLDDSERAHLHTLARAPRRSRAVGRPPV
                     ERVTPATSALLAAIEGTPAVVIGRRSDVLAWNRPGHALFAGHLDQDSPDDPGRRPNMAR
                     LVFLDAHTRDLYTDWPAKARAVVGNLRLTAGRFPDDPLLAGLIGELAMRSPEFATMWAD
                     HRIQACDVADYEMRHPLVGTLAVTQQTLQSPQGSGPSLVVATAAPGSPSATALTLLVHS
                     TAPRESTQPRHGAETRTI"
     gene            19372..19914
                     /locus_tag="ASD48_RS32990"
                     /old_locus_tag="ASD48_23405"
     CDS             19372..19914
                     /NRPS_PKS="Domain: Polyketide_cyc2 (22-139). E-value:
                     6.2e-17. Score: 54.3. Matches aSDomain:
                     nrpspksdomains_ASD48_RS32990_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125806.1"
                     /locus_tag="ASD48_RS32990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23405"
                     /product="SRPBCC family protein"
                     /protein_id="WP_057605469.1"
                     /transl_table=11
                     /translation="MTATCPDPRNPLAGIDLAPFAFTRRCWVDATPDSVYDLISDVSLI
                     ETWSPSAGGVSYAPGDGPWAGARFSGRNRRDGREWVTHSEVVRADPGTAFAFVVGGADD
                     GIVRWDWRFHEQGRGSIVQQSWRLLRADPILGDTLQDVHSLRDHMADSAESTLLALAEW
                     IADRRTPAGHRTRTRTR"
     aSDomain        19438..19788
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS32990_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="6.20E-17"
                     /label="ASD48_RS32990_Polyketide_cyc2.1"
                     /locus_tag="ASD48_RS32990"
                     /protein_end="139"
                     /protein_start="22"
                     /score="54.3"
                     /tool="antismash"
                     /translation="TRRCWVDATPDSVYDLISDVSLIETWSPSAGGVSYAPGDGPWAGA
                     RFSGRNRRDGREWVTHSEVVRADPGTAFAFVVGGADDGIVRWDWRFHEQGRGSIVQQSW
                     RLLRADPILGDTL"
     gene            20184..20354
                     /locus_tag="ASD48_RS32995"
                     /old_locus_tag="ASD48_23410"
     CDS             20184..20354
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014047552.1"
                     /locus_tag="ASD48_RS32995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23410"
                     /product="hypothetical protein"
                     /protein_id="WP_057605601.1"
                     /transl_table=11
                     /translation="MVPILLVLLLALILFGAGFALKALWWIAVIVLIVWVLGFVIRPAA
                     SGGKRGRWYRW"
     misc_feature    20599..20613
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.07"
                     /tool="antismash"
     misc_feature    20696..20705
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.82"
                     /tool="antismash"
     gene            20702..21055
                     /locus_tag="ASD48_RS33000"
                     /old_locus_tag="ASD48_23415"
     CDS             20702..21055
                     /GO_function="GO:0042314 - bacteriochlorophyll binding
                     [Evidence IEA]"
                     /GO_process="GO:0019684 - photosynthesis, light reaction
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507582.1"
                     /locus_tag="ASD48_RS33000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_23415"
                     /product="PRC-barrel domain-containing protein"
                     /protein_id="WP_057605470.1"
                     /transl_table=11
                     /translation="MSDSIWGYQPTTGHTTGTDLIGYTVEATDGSIGKVDKHSDDVTSS
                     YLVVDTGVWIFGKHVLLPAGTVKTVDQAERKIHVDLTKEQIKNSPEFDKDKHVGDAGYH
                     EQVGGYYQNHRSV"
     gene            complement(<21314..>21508)
                     /locus_tag="ASD48_RS45785"
                     /pseudo=""
     CDS             complement(<21314..21508)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669963.1"
                     /locus_tag="ASD48_RS45785"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="2-oxoglutarate and iron-dependent oxygenase
                     domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MENLNSPQFRGYTRTGTECTAGSADRREQIDIGPWRAAVDTGPDD
                     PDYLRLVGPNQWPSALPELR"
     misc_feature    21857..21873
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.42"
                     /tool="antismash"
     misc_feature    22178..22191
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.11"
                     /tool="antismash"
ORIGIN
        1 gcggcgaaca tcctcggcgg ccgctgggac gacgacacga cgtccccgtc gctggagcag
       61 ctggacgaac ccacggcctc gggagtcccg gtgctggcga agcgactggc cgtcgatctc
      121 ggcacggtcg ccggggtacc ggggaagatc gagggcgtcg ccctcgtgga ccacgacacg
      181 ctggccctcg tcaacgacaa cgacttcggg atgacggacg gcaccggagc gttcgacgcg
      241 cagggccggc tcgtcgacag cggcatcgag acgacggtca cctacgtgcg gctgccgcgc
      301 ggcgtgtgag cgacggcccc tcggcacgcg cgcgtggcgg tgtgcggcgg ccacgcgcgc
      361 gtgaccacta gggcagcagc tcctccaggg acggcaacaa cgactcgaga tcgctcggca
      421 ggtcgctggg caacgcggtc ggcagtcggc tcggcagtcg ggtgggaagc cgcgacggca
      481 gttcggtcgg caggccgctg ggcagctcga ccggaagact gaaggacggc gcgggagtgg
      541 caccggtgct gttgccgacg tccggctcgt cggccggcga atcgtcgcct ctcatcagca
      601 cgacggcgac cacggctccg gcggtgacga gcagcgcgag gacgacgaag aggggattcc
      661 gccgccttcc ggacccgccc ggcggacccg acggtggcgg cgaccagccg cccccgcccg
      721 tcccgtcatc gggtccgtag ccggaacgcg gcggtccgaa gccgcccgga ggcggcatgt
      781 cgcccggcgg tccgggcggt tggggcggta cgggcggcat ggccataccg tccagcgtcg
      841 cggtgaaccg ctcgcggcgc gagccccgca gggaagttga taccgactca tgccatggac
      901 cgcatgattc cggcgtattc cgcgcggaga cagctcgaag ccgggcgagc aacgcgcgga
      961 ggcccgcacg acgaccgagc gacgaccgca cgacgaccga acggagaccg agcggagacc
     1021 gagcggaacc gggcgttcga cggcacgcgc gtgtgcacgc tcaccagtgc acacacgcgt
     1081 gcgtgccggt tcagccccgg gcgcccagga ggtggtccat ggcgagctgg tcgaggtgct
     1141 cgaacgccat gccacgggcg gcggccgtct cggcgtcgaa gtcctcgaag gcggtgcggt
     1201 cggcgagcag gctgtccagg ccgtcgggcg cggtggcctg ggcgagctcg tccaggcgcg
     1261 aggcgcgcag ggcctcctgg acctccgggt cgccgcggaa ggcgagcgcg cgctccttca
     1321 ggatcaggta gttgcgcatg cagccggcgg ccgaggccca cacaccgtcg aggtcctcgg
     1381 tgcgcggcgg cttgaagtcg aagtgcttcg ggcccgcgta cccggcgctc tccagcaggt
     1441 cgaccagcca gaacgcggag cgcagatcgc cggcgccgaa gcgcaggtcc tggtcgtact
     1501 tgatgccgga ctggccgttg aggtcgatgt ggaagagctt gtccgcccac agcgcctggg
     1561 cgatgccgtg cgggaagttc agcccggcca tctgctcgtg gccgacctcc gggttcacgc
     1621 cgtacagctc cgggcgctcc aggcgctcga tgaaggccag ggcgtggccg acggtgggga
     1681 gcaggatgtc gccgcgcggc tcgttcggct tgggctcgat ggcgaacttc aggtcgtagc
     1741 cctgggaggt cacgtactcg ccgaggaggt cgaaggcctc cttcatgcgg tcgagggcca
     1801 cccgtacgtc cttggcggca ccggactccg cgccctcacg tccgccccag gcgacgtaga
     1861 tcttcgcgcc gagctcgacg gccagatcga tgttgcggat cgtcttgcgc agggcgtagc
     1921 gacgcacgtc acggtcgttc gccgtgaacg cgccgtcctt gaagacgggg tgcgtgaaga
     1981 ggttggtggt ggccatgggc acggtcatgc cggtggtgtc cagggcctgg cggaagcgct
     2041 tgatgtgctc ctcgcgctcg ctctcggagg acccgaaggg gatcaggtcg tcgtcgtgga
     2101 aggtcacacc gtaggcaccc agctcggcca ggcgctgcac cgactcgacc gggtccaggg
     2161 cacgccgcgt ggcgtcgccg aacgggtccc gtccctgcca gccgacggtc cagaggccga
     2221 aggtgaacct gtcgtcgggg gtgggctggt agctcatacc gcggctcctt gcttgaagac
     2281 tgtgtcgctg actgtgtcgc gagctatttc gtcatggcag tttacaaatt agtatgcgaa
     2341 cgcatctctg ggaagacaga tcccgcagag ccgcggaaaa acttgaggga gaacccgatg
     2401 tcagcagccg agggtccgct cgtcgtcggc gtggacacgt ccacccagtc caccaaggcg
     2461 ctggtcgtcg acgcggccac cggccaggtc gtcgcgagcg gccaggcacc gcacacggtg
     2521 acctcgggcg ccggccgcga gagcgacccc cgccagtggt gggacgccct gcgcgaggcc
     2581 ctgcaccagt gcggtgacgc ggcccgcgag gccgccgcgg tctcggtcgg cgggcagcag
     2641 cacgggctcg tcacactgga cgagcgcggc gagccggtgc gtccggcgct gctgtggaac
     2701 gacgtgcgct cggccccgca ggcacgtcgg ctgaccgagg aactgggcgg agcgaagttc
     2761 tgggcggaac gcaccgggtc cgtgccggcc gcgtccttca cggtcacgaa gtgggcctgg
     2821 ctggccgagc acgagccgga ggccctgcgc gccacgaagg ccgtacgcct cccccacgac
     2881 tacctcaccg agcgcctcac gggtgagggc accaccgacc gcggtgacgc ctccggcacc
     2941 ggctggtggg cctccgcgac cgagtcgtac gacgcggaga tcctcgccca cgtgggactc
     3001 gacccggcgc tgctgccccg cgtggtgcgg cgcggagaag tggcgggcac cgtacgcgac
     3061 agtcacgacc tgcccttcgc caagggcacc ctggtcgccc cgggcaccgg ggacaacgcg
     3121 gcggcggccc tgggcctcgg gctgctcccc ggcacgcccg tgctgagcct cggcacctcg
     3181 ggcacggtgt acgcggtcgc caagcgccgc cccaccgacc ccaccggcac cgtggccggg
     3241 ttcgccgacg cgcacggcga ctggctgccc ctggcctgca ccctgaactg cacgctcgcc
     3301 gtcgaccgcg tcgccgccct gctgggcctg gaccgcgagg ccgtggaacc cgccgcggac
     3361 ctcacgctgc tgccctacct ggacggcgaa cgcaccccca acctgcccaa cgcctcgggc
     3421 ctcctgcacg gtctgcgcca cgacacgacc gcgggccagc tgctccaggc cgcctacgac
     3481 ggcgccgtgc actccctgct cggcgcgctc gacctggtcc tcgacgagga cgcggaccgc
     3541 tcggcgcccc tgctgctgat cggcggcggc gcccggggca gggcctggca ggagaccgtg
     3601 cgccggctgt ccgggcggcc ggtccaggtg cccgaggcca gggaactcgt cgcgctgggg
     3661 gccgcggccc aggcggcggg cctgctgacc ggcgaggacc cggcggccgt cgcccgccgc
     3721 tggaacacca cccggggtcc ggtgctcgac gcggtcgagc gggacgaggc gacgctcgcg
     3781 aggatcgccg gggtactctc cgacgcggcc ccgctgctgg accggagcac gggcgcccac
     3841 tgagcatcga cgaatcgacg gaggcatgac cgcaccgctg cacgaggccc ggccgaccgg
     3901 cccggggcgc gcactgcccg acacccagca gggcatgcgc cgccgcaacc tggcccgggt
     3961 gatgcacgcc gtcagggccg agggacccct ctcgcgcgct gcggtggcct cacgcatcgg
     4021 cctgacccgg gccgcggtct cgaccctcgt cgacgaactc atacgcaccg gactgatcga
     4081 ggagctgggc cccgagcggc cgggccgggt gggccgcccc ggctcggcac tggcggtcag
     4141 cgggcacggt ccggcgggca taggtgccga gatcggcgtc gaccacctgg tggcctgcgc
     4201 cgtcgacctg cgcggggagg tgcgggcacg cgccgtacgg cacggcacga accggggccg
     4261 ctcccccgag ccggtggtcg aggaactgac cggcctcgtg cgccaggtgg tcgccgaggc
     4321 cgaacgcgag gggctgtggc cggccggact cgccgtggcc gtccccggcc tggtcgcccg
     4381 cgacgcccgt accgtcgtcc gcgcgcccaa cctcgactgg caggacgtcg acctcggcgc
     4441 gctgctgccc gggcagttcc cgctgaccgt ggacaacgag gccaacttcg gcgggctggc
     4501 cgaactctgg ctcggcgcgg acactccgga gaacttcctg cacgtgtcgg cggagatcgg
     4561 catcggtgcc gcgctggtcg tggacggcag cctgctgcgc ggcacccgcg gcttcgccgg
     4621 tgagctgggc catgtgccgg tgcaccccga cggaccggag tgcgggtgcg gagggcgcgg
     4681 atgtctggag cagtacgccg gcgaggaggc ggtgctgcgg gcggccgggc tggaaccggg
     4741 cgaggaccgc gtcggactcc tcgcgggacg cgcagcggac ggcgacccgg acgtacggcg
     4801 ggcgctgcgc gaggcgggaa cggccctcgg tatcgcgctc acgggggcgc tcaatctcct
     4861 ggacccggag ggcgtcgtgc tcggtggcgc cctggccggg ctcgcgccgt ggctgctgcc
     4921 gtcgctcgag gccgagctct cccggcgtac ggcgggcccc gcccgtgcgg tgtccgtctc
     4981 ccggctgggc cccgagggcc cgttgctggg ggccgcgcac tcggtggtgc gggccgtgct
     5041 ggacgatccc gcggcagtgg cggagcgggc ctgagccgac gggccgtggg ccggaccgcc
     5101 ggtccgggac cgggaggcgt gagcctcgca ggcgtcggat ccggcgcctc cgccgggctc
     5161 accggtcgcg tcacaggccg gcatccgcgc tcacctcggc cggggtgccg atgtgacggg
     5221 ggccggaact ccccgttcgg gtgagcgagt tgtccacaat cgcgcactcg tccaccgaag
     5281 cccggcgtgt cctcctgacc gaccggtcgg cgccgtagcg taatgcctcc gggacacggc
     5341 cgccgtgcgg tgacggcagt gcccggccgg tacgggatca cgggttcggc gagtcggacg
     5401 cgtaccggat cgaccgccgc cccgtacgcg ctccggtgcc gcccgccgga cgtccgagac
     5461 cccgaaaggc gacacctctg tggaacgagc gaaatccctc cccggacgac gacggatcct
     5521 gaagggcgcc gccctggccg ccgttcccta cgtgctgctg cccgacgcac cggcgggcgc
     5581 ccggacccgg agcgtcgact acccgcgcgc cgagtggcag cccgcggccg ccgccaaccg
     5641 cacggccgcg aaccgccctc tcggccatcc cgtcgaccgc gtcgtcatcc atgtcacgca
     5701 gaccctctac gccaaagccc tgaccgtctt tcagaacccg cgcaagaggg tgtccgccca
     5761 ctacgtcgtg cgctccgtgg acggtcatgt ggcgcagtgc gtgcgcgagt cggacatcgc
     5821 ctggcactcg gggaactggg gttacaacac ccgcagcatc ggtatcgagc acgagggctg
     5881 ggtcgacaga cccgtctggt tcaccgacgc cctctacgaa gggtccgccc ggctgacggc
     5941 atcggtctgc gaccggtacg gcatcccgaa ggaccgcgcg cacatcatcg gccactacga
     6001 ggtgccgggc accgatcaca ccgatcccgg tccgaactgg gactggagcc gctacctgag
     6061 actcgtctcc cgcgcctgaa ccgaaccgga ccgcggaccg gaccgccctc cggaccgccc
     6121 tccggaactc catccggacc gccgtccgga ccgccgtccg gaccgcaagc ggatcgtcgc
     6181 gttcggagtg acgtcgtcca aacggttgtc ggtccgcgta cccggcgtga cgatgtcccc
     6241 agccgtatcc ccttccggga ggacgagttg accgatccct gggtggccct cgaaccgggc
     6301 gccgaccccg ccgagcgcgt gcgggtgctg cgccgggcgc atgagacgtt cgccgaggcg
     6361 ggcaccgtgc cgcggccggt gcgctccgtc gtggccgact cctggcggcg ttccgcccgg
     6421 gccggcgtcg gtcccgacgg cgcggcgagc gtcgagctga ccgacggcga tctcggctcc
     6481 taccggtccg agcatccgct ggcgcgggtg atgccgttgt tccgtgaact gatgggcacg
     6541 ttcgcggccg acggtgagca tctgctggcg gtgtgcgacg cgcacggcag gctgttgtgg
     6601 gtcgaggggc acgcggcgac ccggcgccag gcggggcgga tgaacttcgt accgggtgcg
     6661 cgatgggcgg agagcgcggt agggacgaac gcgcccggca ccgcggtcgc cctggaccgg
     6721 ccggtgcagg tgttcgcggc cgagcacttc atccggcggg tgcagccgtg gacgtgcgcc
     6781 gccgccccgg tgcacgatcc gcggaccggg cgggtgctgg gtgccgtgga catcacgggc
     6841 ggggacggcc tggcccatcc gcacagcctg gccttcgtcc aggcggtcgc gcgggccgcg
     6901 gaggcccacc tggcgctgct cgccccggag cggcccgccg tcgacgcacc gcggctgacc
     6961 gtgctgggcc gggacgaggc gcgtctggtc accggcggac gtgacctcag actgagccgt
     7021 cggcacagcg agatcctggt gctgctggcc cgccgccccg aaggcctgac gggcgacgag
     7081 ctgctgtgcg cgctgtacga ggacgagtcg gtcccaccgg tgacactgcg ggccgaactc
     7141 gcccggctgc gcggggtgct cggccccggg ctgctggcct cgcgccccta ccggctcacc
     7201 gtcgcctgcg agtcggacgt cgccgtcgtc gaacgaaggc tggcggcagg cgcggtcacg
     7261 gccgccgcga cggcgtacac cgggccgccg ctgccgtcgt cgcaggcacc ggcggtggca
     7321 cggctcagaa gccgtctcgc cgagggtctg cgcgccgcgc tgatcgcgcg cggcgatccc
     7381 gatctgctgg cggactgggc gcacgccccg tggggcgagg acgacctcga cgtgtggcgg
     7441 gcgctcgcgg cggcccgccc gacggccgcg atacgggctc gcctcgcgtc cctcgagtcg
     7501 gagctgacgg cgccgaccgg atggccgcac ccgtaggccg ggcgaggcga cctcagccga
     7561 ggcgtcggcc cgcaggacgt gccggccgtg acgtcggcag gcaggacgtg gcgcagccga
     7621 ggcgtcggca agcaggacat ggcgcagccg aggcgtcggc aggcagagcg tcggtggaca
     7681 cggtgtcggt ggacacggtg tcggtggaca cggtgtcggt ggacaaggcg gcccggcggg
     7741 cagcgcaacg tggatgcaac gtcagcctgc ctagcctccc gcggagagct gcccaacggc
     7801 gggcagcgct gctgagggag gcagagcagg atgacccgtt acgcggcgcc aggcaccgag
     7861 ggcgcgatcg tctcctacca gacgcggtac gaccactaca tcggcggcgc gtacgtgccg
     7921 ccggcccggg ggcagtactt cgacaacccg tccccggtca acggcgagac gttcaccgag
     7981 gtggcgcgcg gtacggagga ggacgtggag ctggcgctcg acgcggcgca cgcggcagcg
     8041 cccggctggg gccgcacctc ggcgaccgag cgctccgaca tcctgctgaa gatcgccgac
     8101 cgcatggagg cgcatctgga gcccctggcg gtcgcggaga gctgggagaa cggcaaaccc
     8161 gtccgtgaga cgctggcggc ggacatcccg ctggccatcg accacttccg ctacttcgcc
     8221 ggcgcggtgc gggcccagga gggatcgctc agcgaggtcg acgacgacac ggtggcgtac
     8281 cacttccacg agccgctcgg cgtcgtcgcc cagatcatcc cgtggaactt cccgatcctg
     8341 atggccacct ggaagctcgc gccggccctc gccgcgggca acacggtggt catcaagccc
     8401 gccgaacaga ccccggcctc gctgcactac tggatgagcc tggtcgcgga cctgctcccg
     8461 ccgggcgtgg tgaacatcgt caacggcttc gggccggagg cgggcaagcc gctggcgtcc
     8521 agcccgcggg tggcgaaggt cgcgttcacg ggcgagacgt ccacgggccg gctgatcatg
     8581 cagtacgcgg cggaacacct gaagccggtc accctggagc tcggcggcaa gtcaccgaac
     8641 atcttcttcg acgacgtgtg ggagaaggac gacgaccttc gcgacaaggc cctcgaaggc
     8701 ttcaccatgt tcgccctgaa ccagggcgag gtctgcacct gcccgtcgcg cgggctgatc
     8761 cagcgcggca actacggcga cttccttcag gcggccgtcg cccgcaccga gctcatcaag
     8821 cccggccacc ccctcgacac ggacacgatg atcggcgcac aggcgtccgg cgaccagctc
     8881 gcgaagatcc tctcctacat cgacatcggc cggaaggagg gcgcgaagat cctcaccggc
     8941 ggcgaacgcg cggagtacga cggcgagttg aagggcggct actacgtcca gccgacgatc
     9001 ttcgagggtg acaaccgtat gcggatcttc caggaggaga tcttcggtcc ggtcgtctcg
     9061 gtggcctcgt tcgacgattt cgacgacgcc gtcaaaatcg ccaacgacac gtcgtacggc
     9121 ctcggggccg gagtgtggac gcgggacatc aacacggcct accgcgcggg ccgggcgatc
     9181 caggccggcc gcgtctggac gaactgctac cacgcgtacc cggcgcacgc cgccttcggc
     9241 gggtacaagc agtcgggcat cggccgcgag acgcacaaga tgatgctgga gcactaccag
     9301 cagacgaaga acctgctggt gagctactca ccgaagaagc tgggcttctt ctagagcccc
     9361 gagggtaatc ccgcctcggc gagggtcggc ggcaagcgcc tggaggtttc cctccccgtc
     9421 ttcctcggca tgtcgccggc ccgctccgga ctcgccgacg gcgatggagc gacgggaagc
     9481 ggcgcacgtc caggagcgag gagtgcgccg ggcggcgctg cccgtggccg ccgtcgggcg
     9541 cgctccgaga ggaacggcag gcatctgccg ggactcaggt caaaacgctt ctttgaacaa
     9601 gcgcataccc gacgctcgaa acaatgcggt ggcaaaagca atgacaggga gcgggcgcgc
     9661 actccgagga atgcgaattc tccatattag ctgaactctg tagacgctct tgccctgggc
     9721 tcacggtctg cagctagcta ggtgctgcgt ccacttcctg gcccgggttc ccgatgagcc
     9781 cagggcagat cgacagcaca ccggaaagtc ccggggccgt cactcacgga ggtggtcggg
     9841 aaacccgtac gtgaggagtg gtcatgaaga aggcatacga ggctccgacg ctcgtccgac
     9901 tcggcagctt ccggaaggag accgggctcc tgggacgctc cggcaacgac cggctgatcc
     9961 tgagcaagaa ctgacgaccg acggtccttg acccgacgtc atgactgaac tgcacgaaag
    10021 tgcggggacg ggccccggcg acgcgcactt cgcggtcttc accgaccgtg cggacgcggc
    10081 cgccgcggcc cgctccttcg cccttcccgg aagccggacc ctcacgcacg cgtcgggccg
    10141 gccctggctg gtcggccact ggcacgacga cgaggtcgtc acggggaacg cgggcggcgc
    10201 cgccctcgcc gtggtcggct gctgccctgt caccgccgac gaactacggc gccgagccgc
    10261 acggttgcgt gatctcacgg agctcgacgc gctggcccgg tcccttccgg gcagcttcca
    10321 cctcgtcggc gccctcgacg ggcaggtcag ggtccagggc accgcctccg gactgcgact
    10381 cgtcttccac gcggagatcg atggcctgcg ggtggccgcc acccgtgccg acacgctcgc
    10441 cgccgtcctg ggcctagacc ccgacgtcga ggagctggcc gtgaggctgc tgtggcccgc
    10501 cccgtatccg ctgttcgaga catccctgtg gcgtgcggtc accgccgtgc ccccgcagga
    10561 cgccgtggtc gtcaccgcgg acgggcgcac cgcgcggcac acccgatggt ggacgccgcc
    10621 ggagccggtc cgaccgcttg ccgaagcggc gcctctgatc cgaagggcac tggaggaggc
    10681 cgtcggcgcc cgtacccggc agggcggcgt ggtcagctgc gatctgtccg gcggcctgga
    10741 ctcgacctcc gtctgtttcc tcgccgaccg ctcccccgcc cgcgtggtgg ccagtacctg
    10801 gccgggacgc gatccggcgg acaccgacct gcactgggcc gagcaggcga tggggcacct
    10861 cccggacgtc gagcacgtgg tctgggacgc cgacgcgtcg ccgctggtct acgaggacct
    10921 gctcggcatc gacgacctcc tcgacgagcc gaccatcggc gtcatggacc gatcccgggt
    10981 cctgcaccat ctgcccggcc tcgcctcgcg cggcagccgt ctgcacctga ccggcatcgg
    11041 cggcgaccac gtggcatggt gctccgaggc ctactaccac cgactgctgc gtacccgacc
    11101 gctgttcgcc gtgcggcagt tgcgcgggtt ccgggcgctg tggcagtggc cgctcggcgg
    11161 cacggcccac gcgctcgccg actcccggtc gtacgggaag tggctcgccg acgccgccgg
    11221 ccgcctgcgc ggtccgttgc ccccgtccgt cgcgacgggt ctcggctggg gcatggctcc
    11281 gcgcctgttc gactgggtga ctcccgaggc cgaacacatg gcccgccggg cactgcacgc
    11341 ggccgcggcg agcatctcgc cgctgcatcc ggaccgtggc atgcacagcg acctggagca
    11401 gatccgctcg tgcacccgcg tcatccgcca gtgggaccgg atggcggccc gcgccggtct
    11461 gccgatggcc tctcccttcc tcgacgaccg cgtcatcgag gcgtgtctcg ccgtacgccc
    11521 gagcgagcgg gtcacgccct ggacgtacaa gcccgtcctg ggcgccgcga tgcgcgggat
    11581 cgtgcccgag gcgtgcctgc ggcggtccac gaaggccacg gcctccatgg acgcctccaa
    11641 cgggcttcgc gaacaccgcg cggacctgct ggccctgtgg gaggactcgc ggctggagga
    11701 gctgggtctg gtggacgccg ccgaactccg ccgcctcgcc cggcggcccg cctctccggg
    11761 attgtccgac gccatcctct actccacgat cgccgccgag gtgtggctgc ggggcatctc
    11821 cggcagccac acccgtgtcc cccacctctg atcacatccc tacgtcagaa aggccctcac
    11881 atgcctctgc ggttcggcgc cgacgtctcc acggccgaga ccgactacgg cacggtgctt
    11941 ctggacgaac gggtcggcgc ctactgggag ttgaatccga ccgccaccct ggtcgtacgc
    12001 acgctgatcg acggcgggga ggagtcggac gcggccgccg ccctggtccg ggagttcgac
    12061 atcgacgagg cgcaggccct gcgggacgtc gaggcgctcg tgggacagct gcggagctcg
    12121 ggactggcct catgacgacg cccagcgcgc tggaacgacc caccggtgtg cccatggccc
    12181 gacgcctggc cgcccacctc gtcctgctcc ccgccgtcgc cctcgccctc ctgccgcccc
    12241 ggcggatccg caccgtactc ggcatcctgc ggcgcggtgc cgcacccgcc accaccaggc
    12301 acgcccagaa cgcgcgcgac gccatgtgcg ccgccagcct gcactgcgcc ggaccgaagg
    12361 ggtgcctgcc gcgctctctg ggggcggcac tgctgtgccg gctcggcgga acgtggccga
    12421 cctggtgcac cggcgtgcgc gtcgtcccgc ccttcaccgc gcacgcgtgg atcgaggcgg
    12481 aaggcagtcc cgtcggggag ggtgcgccgg agggctactt cgcccggctg gtggccgtcg
    12541 ccccgctgcc acgaccgacg gaccgatgac cggcacaacg gtcgcgaacg gcggcccggc
    12601 ccgggtcgcc gagggggaca agtccacccg gacggcggtg gccacgatgt accggctcac
    12661 cgccgggcac cggaacgcca tcgccgtcgc caccgtactg accctcatgg gctccgccct
    12721 gggactggcc cagccactca tcgccaagca cgtcgtggac gcgagtggcc gcgggcaggt
    12781 catctggcca ctgctggcac tcctcggcgc gctgttcgtc acggaagcgg cgacgggagc
    12841 cgcggggcgc tttcttctgg aacggatggg cgaacgtgtc gtacggcagg tccggcacgg
    12901 gctggtgggg cggctgctcc ggctggagat gagggagtac gaccgccagc ggggcggcga
    12961 cctcatctcc cgggtgacgg ccgacaccac cttgctcagg gaggtcgtgt cgcaggccct
    13021 cgtcgacctg gtgacgggaa gccttgtcgc cgcaggggcg atcgtcctca tggcgtggct
    13081 cgaccccctg ctgctgctca tggtcgccgt caccgtggcc gcggcggccc tggtcgtcgc
    13141 ctcgctgctc acgggcatcc gaggcgcgtc cgaacacatg caggactcgg tcggcgccat
    13201 cgccgccgac cttgaacgcg ccctcggcgc cctgccgatg gtccgcgtgc attgcgccga
    13261 ggagcgcgag gctgcgggca tcggcgcacg cgtcgaggcg gcctacggcg cgggggtacg
    13321 caccgcgaag ctcgcctctg tcatgagccc cgctgtcgaa ctcgccgtcc agggctcctt
    13381 cctcatcgtc ctggtcgtcg gcggcctgcg cgtcaacggc cacgccggct ccctcggcga
    13441 cctcgtcgcc ttcctgctgt acgcctcgta cctcgtcctg ccgctgtcct ccgtcttcca
    13501 cgcggtgggc ctcatccaac gcgggatggg cgcctaccag cgcatcgacc aggcgctccg
    13561 gctgcccgtc gagcccaccg caccgcggat ccgaagagtc cccgtcccca cacccgcgcc
    13621 gaccgggccg tccgacaccc tcgagcagcc cgccctcgcc ctgcgggacg tccgcttcgg
    13681 ttacgccccg gaccggccgg tcctccgcgg cgtttcgttc gccgtcccgc accggcagca
    13741 cgtcgcactc gtgggtcggt ccggagccgg caagagcacg gtgttcgccc tggtcgcgag
    13801 gttctatgag ccggacgcgg gccacgtgct cttcgacggg ctgcccgccg cccaactcac
    13861 ccgtgacgca tgccgccggc gcatggccgt cgtcgaccag aacgcgcacg tcgtccgcgg
    13921 gaccctgcgc gacaacatcg tctacgccgt tcccgacgcc acggaagcgg agatcaggcg
    13981 cgtcatggaa ctggcccgac tcgacgaagt cgtcgaccgg ctgcccggcg gcctggccgc
    14041 cgtcatcggc gaacgcggca gcaccctctc cggcggagaa cgccaacgcg tcgccatcgc
    14101 gcgggcgttg ctggcccgcc cctcgctgct cctgctggac gagcccacct cccacctcga
    14161 cgcgatcaat gaatcggccc tcaccaccgt catgaaggac gtcgcccagg agtgcgctct
    14221 gctggtcatc gcgcaccgcc tgtctaccgt gcagcacgcc gaccacatcg tcgtgctgca
    14281 cgacggccgc accgccgccg gcggacgcca cgaggagttg ctggccgtca gcgccctcta
    14341 ccgcgagctg gccgcgagcc agatgctccg gccgggcggg caccccggaa acggcgaccg
    14401 agcggggaca tcgggttgaa gccatgccgt cctcgcggcc cggtcggccc gagatccgga
    14461 ccatgcacgg ccaacggccc agctgtcgcg gccatgggct caccagtcat ctgttgtccg
    14521 ccccccccaa ccgatccccc caccgatcct tctgccgagt cccgttcggc agggtcccgg
    14581 cgcacgttca tcgcgacgac caccgcggtc gggggtgccg tcggcggcgg cctggtcgcg
    14641 gggtcgctcc cgttgggtgc ctcggcggcg accgccgccg aggcaccacc gagtccacag
    14701 aacgcgtacc cggcggagac ggaactccct caccctgccg gccggcagcc accatcgtcg
    14761 acggaccctg cggcgtagtc cgaggtcagt cggtagacgc ccgcccgggg cgcggtcagc
    14821 cgggtccacg gaccgtccgc gctgacgcac gctccctcgg cccgcaacca cggcgaatac
    14881 gcgatccgca cggtgctcgt cccggcgcga ggcatcctca aggtcagccc tgcctctccc
    14941 gcgtgctgca acacggccgg agcggagacc agcggcagag tgtcgcgcac gcggtagatc
    15001 ttccagtacc ggtcctgcca gacgagctcc agccagtgtt gtccctcctt gatcagagcg
    15061 gtctcgcgct ccgcggaccg atcgggcggg ccgtcgtgca gcacgacgta gcccacagcc
    15121 cagtggcgca gccaggcgtg gtaacgcggc ccgtcgaggt cgccctcgta gaacaggcgt
    15181 ccccgttcca cgtccaactg ctgattccag ccccgcatca gttcgacgtg cgggccgagg
    15241 agggtggccc cgcggtggtc gcgatccgtc ggcaattcga cacggccgcg gtccgcaccc
    15301 aggcgggcga gcgcggcgag cactccgtcg gtgtgcgtga cccagcccgg aacggggtcc
    15361 gggctccgca gatgcatcag cgacgtcaca cagagatagg agacggagag agccgtcacc
    15421 agagccatcg cgcgcatacg agttcggcgt acgccgttcc gggtggctcc ggagcggcgg
    15481 tgcagcgcgg ccgcgagcaa caccgcgggg gcgaagagca gggcgaggcg ctccacgttg
    15541 ttgccgatcg gtgaggggac cagccaggtc aggacgaccc cggcggcgta cagggcgctg
    15601 cctgcccgca ccacccgcca cttgcgcggg gacgcccaca ccacggcggc ggacaacagc
    15661 acgggcagga tcatccggcc cgcggccatg ggctgttcgc catggaaggg gaacagcagg
    15721 gtcgtcaagc cgacgacggc gacgggcggg agagtcaggg cgagacactt gccgtactgc
    15781 cgggtgacca gatacccggc gcccgccacc agcaggaaga gtccggccac cgggctgccc
    15841 atggtcgcga acagcgcccc gaacgcggcg gcggcaagcc gggccgggcg gggcgcacgg
    15901 tcggccacgg cgagcaggcc ggcgagagcg aaggccagac cgagggcgaa cgtggtgcgg
    15961 ccgagcacga cgttgtacca gaggcccagc gctccgacca gcccgggcca cagcgacaca
    16021 cggggaacgg tgcgctccag cagcatggcc agcagacagg tggcactgac tccggacagc
    16081 acggagacag cacggacacc gagcagtgcc atcaagtgcg gtgatatgac gctgtaattg
    16141 acggtgtgga ccccgccgaa ccagaagagc ccgtacggcg tgaccgggtg cctgcccacg
    16201 aaccccgccc acgcgtactg cgcggcgagg tcaccgccgt ccgtcgcaag aagggcatcc
    16261 cacccccagt acagggggag tacggcggcg atggcgagga gcgggacgcg gtatctcgcc
    16321 gctccggacg accggcgttc ccggcgcagt gcagaggctg ggggttccag tgaggcgggg
    16381 gtcggcaggg tgaaggactg taggggcata tcggctttcc cggtgcggta cggacgctgt
    16441 acaagcccgc tgaggaattc gtggccctga gggctcctgg aactcgcgga cccgcgcagg
    16501 cgtcacggcc gggtttctcc cgtccgtcgc gcccactcgc gtatcgcgca ccacatcagg
    16561 gcctcggccc ctcggacggc tctcgcgcgt gccgccaccg gaggtccggg ccgttcgttc
    16621 gaggcgctga cggcgtcacg cggcaagccc gtatcagccc gcctcccgcc cgccggggca
    16681 gcgttgaacc acgctgcgcg gatggcgcaa ctcgctgaca gcgccagcac caggaggccg
    16741 acatcgtgca ctgaaccgct ccggaatcgg tgggaggatc cggactgggg cctcctaccc
    16801 aagcggacca cggacatcag ccggatcgcc ccccgaccat gatccggacc attcccgggc
    16861 cggcaaccct ccaccggctt cagcagaggc tatttccaca ggtcagccac aagcaaggcg
    16921 tgtaccacca gcagacgaag aacctgctgg tgagctactc accgaagaag ctgggcctct
    16981 actggacacc ctcccggcag gaccccttga gagggccacg acaccggtcg tggccctctg
    17041 cgtccggggt gggtaccggg gccgggttct acgggcggcc gcccaggcgc gcgcgcagca
    17101 gattggggtc ggcggccgtg gtgtaggcgg cgctgagcac gtacacgtcc ttgccgcgca
    17161 gcgccacgga ggtggggttc tgcagtccgt cggtggcatc cagaacggtg gtgccggtgc
    17221 cgtcggtccg gatgcgcacg accgtgttgg ggccgttgag ggcggcgagg atctcgtccc
    17281 cccggccggt gaaggcgaaa tcgtcgatac cggccaggcc cgaagccttg acctgcggtg
    17341 ctcccgcacg gtttccggaa cggatcggaa tacgcaggac ggtgccccga tccaggttgg
    17401 tcacccacag ggctccgccg tgcaccttcg ctccgttggc gccgaggaag ccggtcgagg
    17461 cgagttcggg ggcggcggac cacgcacggg gtgtgccgcc ggtgacgggg acggtccaca
    17521 cggtgccgag caccgagtcg gtgatgtaga gctgtcggct gtgctcgtcc agcgccagcc
    17581 cgttgggcag gcctcccgcg ggcagtgcgg cgatgcgctg cggtgcctgc ccggggcgca
    17641 gccgccacag ccccgtcagg tcggccgtgc cggtcgcgta cagcacgtac agggtgccgt
    17701 ccgcggtatg ggcgatgccg gtggccaggg ggaagccgag gaccggggtg ccgactccgc
    17761 cgtcggcggg ggcgggcagc gtcgccagga cgcgcgtggc gccccggcgg gtgacctgtg
    17821 ccacctggcg gccggcggcg aaggtgacgg ccgccgtgcc gtcgggcagc agggtgatgt
    17881 tctccggcat ctggcccgtg gacaggtcga agtgggtggc gacccgcaca tgtgtcagcg
    17941 gtcctccggt ggatgtcgcg tcggcgggca cagccgctgc gagggtggcc gcggccacca
    18001 cgactgccga catgatcagc ttcatgcttc ggtgggacat ggggttcctt cactgttctc
    18061 gggcatgcgg cagccgcggt gcgatgccgt gcggtgccgt gcgatgccgt ggacgagggg
    18121 tgcttcgggg atggcgtgat ctgccgaccg gcgggcgtga ggccgtccga ccggcgggcg
    18181 tgaggccgtc cgaccggcgg gcgtgagccg tccgaccggc gggcgtgagc cgtccggccg
    18241 gtgggcgtga gccgtccggc cggtgggcgc cctcgggcga cggaggggct cgggtcagat
    18301 ggtgcgggtc tcggcgccgt ggcgcggctg ggtcgattcc cgcggtgcgg tggagtggac
    18361 gagcagggtg agggctgtgg cggacgggga gccgggggcg gccgtagcca ccaccaggga
    18421 cggtccgctt ccttgcgggc tctggagggt ctgctgggtg accgccagtg tcccgaccag
    18481 cgggtggcgc atctcgtagt cggcgacatc gcaggcctgg atccggtgat ctgcccacat
    18541 cgtggcgaac tccgggctgc gcatggccag ttcgccgatc agtccggcca gcagaggatc
    18601 gtccgggaag cggccggccg tcaggcgcag attgcccacc acggcccggg ccttggcggg
    18661 ccagtcggtg tacagatcgc gggtgtgcgc gtcgaggaac accagcctgg ccatgttcgg
    18721 ccgtcggccc gggtcgtcgg ggctgtcctg atcgagatga cccgcgaaca gcgcgtgtcc
    18781 cggccggttc caggccagga cgtcgctgcg gcggccgatg acgacggcgg gtgtgccctc
    18841 gatggccgcc agcagggcgc tcgttgccgg ggtgacgcgt tcgacgggcg gtcggccgac
    18901 ggccctggac cgcctgggtg cacgggccag ggtgtgcagg tgggcccgct cggaatcgtc
    18961 cagtcgcagg gcgctcgcca cggcgtcgag cacctcgcgc gaggcgttgc gtgactggcc
    19021 ctgttccaga cgggtgtagt agggcgcgct gatgcccgcg agcatcgcga gctcctcccg
    19081 ccgcagcccg ggcacccggc gccgctcacc gtaggtctgc aacccgacgt cctggggccg
    19141 cagttggctg cggcgtgcct ggaggaagtc cgcgaggtgc ccgtgcttgt tcatgtcacc
    19201 gagtatgcgt acggccgacg acccgcgcct caccccgccg gggtagggat ccccggggta
    19261 gggatccccg gggtaggcat cggtgggggt aggcatcggc ggggtctggt tcggcccggc
    19321 ggcggtctcc aggatgggcg cgttcctctt caccgtcctc cgggagaatc catgaccgcc
    19381 acctgcccag acccccgaaa cccgctggcc gggatcgacc tggctccctt cgccttcacc
    19441 cggcggtgct gggtcgacgc gacgccggac tccgtctacg acctgatcag cgatgtgtca
    19501 ctgatcgaga cgtggagtcc gagcgccggc ggcgtcagct acgcaccggg cgacggtccg
    19561 tgggccggcg cccggttcag cggccgcaac cgccgggacg ggcgcgaatg ggtcacccac
    19621 tccgaggtgg tgcgggccga tccgggtacc gcgttcgcct tcgtcgtcgg tggagccgac
    19681 gacggcatcg tgcgctggga ctggcgcttc cacgagcagg gccggggcag catcgtccaa
    19741 cagtcctggc ggttgctgcg cgccgacccg atcctgggcg acaccctcca ggacgtccat
    19801 tcgttgcggg accacatggc cgacagcgcg gagtccaccc tgctcgccct ggcggagtgg
    19861 atcgccgacc gccgcacccc cgccggccac cgcacccgca cccgcacccg ctgacagctc
    19921 gggccacctc cgaacgggct gcctccgaac gacgcggggg tgcgggggtg cggggacagc
    19981 atcctggcgg aggaagagac ccttctccga acggcacccc cttgaccccg gattccactc
    20041 ccaaacggaa attacccgac ggacttttcc tggcggcccc ggcatccgcg cccggcggtc
    20101 cgggctctcc aaaagaaaca cagagcatct acaggagtga agatcgctcc gcagggcaca
    20161 cgatggatcg gaggttgata actatggttc ctattcttct cgttcttctg ctcgccctga
    20221 tcctcttcgg tgccggtttt gcactcaagg ccctgtggtg gatcgcagtc atcgtgctga
    20281 tcgtgtgggt cctcgggttc gtgatccgtc ctgcggcaag cggcggcaag cggggtcgct
    20341 ggtaccgctg gtaggcggac cttcctcacg aacggaacat gggtgggcac cggcgccatg
    20401 gcgccggtgc ccacccatgt tccgttcctc cagcgctccg ttcccctgca ccagcgggac
    20461 gaaaatggtg atctcgttga ttcagggtac ttggaggtcg tggccggagg atgttcgtgc
    20521 cgccaggaac catggcctcc aacacgacgc ctccggccat tcgagttttg cttcggggcg
    20581 aatgcgtgga gggcgaaaat cagggcactc gatttcccga gaaggcgtta ccgaaggtga
    20641 tgacgtcacc ccgcagattc gactgcgggg gtaacgagaa tctcgatgag ggagtcgttt
    20701 tatgagtgac agcatctggg gctaccagcc gaccaccggc cacaccacgg gcaccgacct
    20761 gatcgggtac acggtcgagg ccaccgacgg aagcatcggg aaggtcgaca agcactcgga
    20821 cgacgtcacc tcttcgtacc tcgtcgtcga caccggcgta tggatcttcg gcaagcacgt
    20881 tctgcttccg gccggcaccg tcaagacggt cgaccaggcc gagcgcaaga tccatgtcga
    20941 cctcacgaag gagcagatca agaactctcc cgagttcgac aaggacaagc acgtcggtga
    21001 cgccggctat cacgagcagg tcggcggcta ttaccagaac caccgaagcg tctgacccac
    21061 gacgtcagcc ggaagcgggg ccgacctgag gtactccggt cggccccgct tctcggtctg
    21121 cggcggccaa gcctacgagt gccgctggcg gcgggccgga cgccgatgct gcgacgcatg
    21181 aaggatcgtg ctcatccggc ggccgctctc aggcggccga agtactcctc gccctgtccg
    21241 agcgcggccg ccggcgcccg cagcactccc ggctcacccg taaggcctcg gcctgccagc
    21301 gcggcacgat ctcccgcaac tccggcagtg cggacggcca ttggttcggg ccgaccagac
    21361 ggaggtagtc gggatcgtcc ggcccggtgt ccacggccgc gcgccagggg ccgatgtcga
    21421 tctgctcgcg ccggtcggcg ctgcctgccg tgcactcggt cccggtacgc gtatagccgc
    21481 ggaactgggg cgagttgagg ttctcgatct cccgtcggcg ctgttccggg aaggagggag
    21541 gggaacggaa ggacgagatc gcgggccgtc ggacggcggt caacgacaga tctggtcgaa
    21601 ctggtcggcg cggcggctca cccagaacgg gtcgagcagc accgtgtgtg ccggtctcca
    21661 tggccgggat caaagcacac gcccgcaggt gcgtccacca ggcgtcccga cgggtgagac
    21721 gccggtcggc acgacgaccg ggacggcgac cggcacgacg accgggacgg cagccgggac
    21781 agccacccgt gcgacggcgg ggcacggcgt gccgggcctt ttcgccctcc ccggcctgct
    21841 ggtgcgccgt cagcatctgt ggttttctga cctcatgacc gtccttgtga cccgccgcca
    21901 cgtcgattac gtgcgtgtca ccaccacggg ctgttccacc gcgagctgac gccccactcc
    21961 ggtatccgat ccccctcttg atcctcgcac cgcgctgccc ttcgccctgc ccgcgtccct
    22021 gtccgggcag ccgccgcacg gtcgcttcag gcaccccgca cgccccgggc gcccgcacgc
    22081 ccccgcacaa gggagaacca tgagccagcc gatcgactcc gtcaccgccg gtcacacccc
    22141 cgaggacgaa ccagccggac ccgacacctc ggcctggtcg ttcgagacca agcagatcca
    22201 cgccggcgcc gcgccggatc cgacgaccgg ggcgcgggcg gtgccgatct accagaccac
    22261 ctcgttcgtc ttccgcgaca cccggcacgc cgccgacctg ttctcgctcg ccgagccggg
    22321 caacatctac acccggatcc acaacccgac ccaggacgtc ttcgagcagc ggatcgccgc
    22381 gctggaaggc ggcgtcgccg cggtggcact ggcctccggg caggccgcgg agaccctcgc
    22441 cgtcctgacc ctggcgagcg cgggcgatca catcgtctcc agcacgtccc tgtacggcgg
    22501 cacctacaac ctgttccgcc acaccctgcc caggttcggc atcgaggtgt ccttcgtcga
    22561 cgacccgga
//
