LOCUS       NZ_LMEQ01000030        52469 bp    DNA     linear   CON 07-JUN-2024
DEFINITION  Streptomyces sp. Root1310 contig_4, whole genome shotgun sequence.
ACCESSION   NZ_LMEQ01000030
VERSION     NZ_LMEQ01000030.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root1310
  ORGANISM  Streptomyces sp. Root1310
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 787452)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 787452)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140604
            Assembly Name                     :: Root1310
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001426425.1-RS_2024_06_07
            Annotation Date                   :: 06/07/2024 02:14:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,470
            CDSs (total)                      :: 8,385
            Genes (coding)                    :: 8,123
            CDSs (with protein)               :: 8,123
            Genes (RNA)                       :: 85
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 262
            CDSs (without protein)            :: 262
            Pseudo Genes (ambiguous residues) :: 0 of 262
            Pseudo Genes (frameshifted)       :: 98 of 262
            Pseudo Genes (incomplete)         :: 219 of 262
            Pseudo Genes (internal stop)      :: 20 of 262
            Pseudo Genes (multiple problems)  :: 64 of 262
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:32:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 679270
            Orig. end                         :: 731739
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMEQ01000030.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..52469
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NRPS"
                     /product="T1PKS"
                     /region_number="4"
                     /rules="cds(Condensation and (AMP-binding or A-OX) and not
                     alpha_am_amid)"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..52469
                     /SMILES="NC(C(O)C)C(=O)C1=CC(=O)C(N)C=C1C(=O)CC(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(Condensation and (AMP-binding or
                     A-OX) and not alpha_am_amid)"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="interleaved"
                     /product="NRPS"
                     /product="T1PKS"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..48598
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[20000:28598](+)"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..28598
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(Condensation and (AMP-binding or A-OX)
                     and not alpha_am_amid)"
                     /neighbourhood="20000"
                     /product="NRPS"
                     /protocluster_number="1"
     gene            293..1024
                     /locus_tag="ASD48_RS30265"
                     /old_locus_tag="ASD48_20670"
     CDS             293..1024
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013678689.1"
                     /locus_tag="ASD48_RS30265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20670"
                     /product="cation transporter"
                     /protein_id="WP_057605061.1"
                     /transl_table=11
                     /translation="MAAEISISLGLSPARREALAKRIRLLVAATITYNVIEAIVALTAG
                     TLASSTALIGFGLDSIIEVSSAAAVAWQFSARDHAAREAREQRTLRIIAVSFFALAAYI
                     TFDAVRALTGTGEAERSIPGIVIAALSLAIMPFLSAAQRKAGRELGSASAVADSKQTLL
                     CTYLSAVLLVGLVLNAILGWSWADPIAALVIAAIAVKEGRDAWQGKGCCAPTAHTPASV
                     AAAAAAGADACGCKPGCACCS"
     gene            1104..1886
                     /locus_tag="ASD48_RS30270"
                     /old_locus_tag="ASD48_20675"
     CDS             1104..1886
                     /GO_process="GO:0006810 - transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010070544.1"
                     /locus_tag="ASD48_RS30270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20675"
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_057604932.1"
                     /transl_table=11
                     /translation="MEWTIWAGFAAGLLISTVTAPVGVSGAVFLLPVQLSVLGVPSPAV
                     TPTNLLFNVVAGPGALWRYRRDGALRGGLARRLVAWTLPGVIAGAALRVFALPSPGVFR
                     ILVAALLLPLGAWLCLRTLRPARPRADAAEPSARVLAALALAVGVVGGIYGIGGGSLLG
                     PILAARGMPMARIAPATLAATFTTSLAGAAAYAALALASPGPVAPDWRLGLACGAGGLI
                     GGYLGARLQPRLPETALRLLLGALASALGAVYAAQALT"
     gene            <2416..2541
                     /locus_tag="ASD48_RS43790"
                     /pseudo=""
     CDS             <2416..2541
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368704.1"
                     /locus_tag="ASD48_RS43790"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LSLPYSSGVVEGHVNRIKTIKRQMYGRASFNLLKARILVQP"
     gene            complement(<3150..3342)
                     /locus_tag="ASD48_RS45710"
                     /pseudo=""
     CDS             complement(<3150..3342)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009189493.1"
                     /locus_tag="ASD48_RS45710"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="phosphatase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLDISSWVRVHGGDPASGAEWHGGLRCYRARRTGRKAGRSERTAR
                     SESGRNRFSGSLARTHCRA"
     misc_feature    complement(3803..3816)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.46"
                     /tool="antismash"
     gene            4027..7320
                     /locus_tag="ASD48_RS30275"
                     /old_locus_tag="ASD48_20680"
     CDS             4027..7320
                     /GO_function="GO:0043531 - ADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1173: WD-40
                     repeat-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013124.4"
                     /locus_tag="ASD48_RS30275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20680"
                     /product="NB-ARC domain-containing protein"
                     /protein_id="WP_282438354.1"
                     /transl_table=11
                     /translation="MIDRVQTQQAIAAICGRLHGAMPTVTALEGAGGFGKTTLADVVCA
                     NRKVRRRFRGRIYRVTVGRDVRGRAAIAAKVGEVTRFITGNAEAFEDPELAGAHLGRLL
                     QKRPRILLVLDDVWDAEQLRPFLIGGGNCIRLVTTRRQDVCPGTARRILVDEMSAPEAR
                     RVLTRDLAPLPHETVESLLEATGHWPLLLRLINRVIFAEATLTCGESARAAATTAAGAR
                     VLQQLSETGPTAVDDPWDPPDLNDPVHRTKAVRATIEAAVQLLPENGAERLTELCVFST
                     DDAVPLSLVETLWRKQAGLSTTESQALLRRITSLSLANPVYQETGALALHDVVRDYLRA
                     ELGPAHLTQLHESLVDAVAGQMPSASQLLPDRAAPSRSWWAAEHGYLLDHVIDHLLAAG
                     RNAEAEATISDIRWIEARLLHQGPAATQNDCLRVATESSIQRSRDIGRIAHLLAPTDPP
                     EAVVGILHERLFPIPAWQDEITARRAERLASALIDDGDLPDLPDPSSERTLLGHTDQVL
                     SLAFSPDGTRLASAGDDGFIRLWDLESGSTAHAIKLRFGSLNRIRVLAYSPDGTQLAAA
                     GSFGVRLWDLTAYTATRSLPRRHAGKTRDLAYAPDGTQLATVGHDDKVRIWNPATGKIT
                     AVLSGHTGRVRALSYTPDGRKLATIADDGTMRAWDPVTGATLAAAHGSACKPRFLATSN
                     SHYVVAGNRTREDPFVEIHHRATGELVHEIRLDSSRLEATAYSPDGAQLATAGADGTVR
                     LWETATGAAVHGVHRRLGRVMALAYSPDGMRLASAGADNAVRVSNPHADSSELRFAAAR
                     SLDLSRDGNRAAIALSDKRVLIIETGSDGWRDYTTRSITIPEHAVWRLPVAVSPDGAHI
                     ATGGAEDHAIRIRNQQAGDVTDTLSGHRRKIRALAYSPDGTQLASGASDGVRLWQLASG
                     ASKLRLIGGNVLAYAPDGDELATAGGFGLLVYLLDPVTGQRKGLYKQPESVCALAYSPD
                     GAELAAGLENGRVIVRDRTTAHTQLHSFGAHAAAVNAVSYSPDGLYIATASADLSLRIW
                     GRQGTPVTMTRTEQALESLAWVADASGRVIIGGGGGGWYVWKFKAVNTR"
     misc_feature    5050..5052
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7520..>8047
                     /locus_tag="ASD48_RS30280"
                     /old_locus_tag="ASD48_20685"
                     /pseudo=""
     CDS             7520..>8047
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006383502.1"
                     /locus_tag="ASD48_RS30280"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /old_locus_tag="ASD48_20685"
                     /product="XRE family transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPRGRASSHPSRTAGGPRYEVSQSHRRFRCRRNSSRRPRQHRNPS
                     YRHVRRRPPTTALRRGHRE"
     gene            8198..8476
                     /locus_tag="ASD48_RS30285"
                     /old_locus_tag="ASD48_20690"
     CDS             8198..8476
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982252.1"
                     /locus_tag="ASD48_RS30285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20690"
                     /product="hypothetical protein"
                     /protein_id="WP_057604934.1"
                     /transl_table=11
                     /translation="MFVLLLILVVILFGLGFLNPIWWVAAAVLVFGANRHGRDRGGGWI
                     RDDGSDLGGYRDYENRRDRQDRWDRRYSRRNRARWRREDRRDHERRG"
     misc_feature    complement(8232..8247)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.68"
                     /tool="antismash"
     protocluster    8591..52469
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[28590:32469](+)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      28591..32469
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="2"
     misc_feature    8655..8670
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.27"
                     /tool="antismash"
     gene            8726..8962
                     /locus_tag="ASD48_RS45720"
     CDS             8726..8962
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015799.4"
                     /locus_tag="ASD48_RS45720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_242432785.1"
                     /transl_table=11
                     /translation="MVLAPCRRGTARGLLVDIARQCNTKLPEVAAAMVAAWEGVPLSWP
                     MQQALRRALRRLYAEDRGCGSPLADERSGKGRP"
     gene            complement(<9256..9878)
                     /locus_tag="ASD48_RS30295"
                     /old_locus_tag="ASD48_20705"
                     /pseudo=""
     CDS             complement(<9256..9878)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_037846392.1"
                     /locus_tag="ASD48_RS30295"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="ASD48_20705"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MIDTGDIVVFLGLDVGRGEHHATAVTPAGRKAFDKRLPTTEPKLH
                     ELFSR"
     misc_feature    complement(9555..9557)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    10101..10112
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.08"
                     /tool="antismash"
     gene            10429..10593
                     /locus_tag="ASD48_RS44915"
     CDS             10429..10593
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005486031.1"
                     /locus_tag="ASD48_RS44915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_199876025.1"
                     /transl_table=11
                     /translation="MALFYLLLIAAIVLVIVGATAEGMLYLLSAGVLLLIADVLYRAVR
                     SVLHQRPAH"
     gene            complement(10815..11531)
                     /locus_tag="ASD48_RS30300"
                     /old_locus_tag="ASD48_20710"
     CDS             complement(10815..11531)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019060901.1"
                     /locus_tag="ASD48_RS30300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20710"
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="WP_057604935.1"
                     /transl_table=11
                     /translation="MNQQLLAKTFVELADNLVADFDLIDFLRLLTDRCVGMLDASAAGV
                     LLADRDGKLRVMAASNEHVRLLELFQLQNDEGPCLECFRTGTPVIIPDLTREADRWPRF
                     VTAAHRSGFEAVQALPMRLRDETVGALNLFRVAPGPFDPAGTLIAQALADVATISLLQQ
                     RSSQRSTVLNEQLQAALNSRVLIEQAKGKLAERQGIDMEEAFTALRGYARAHNRRLSDL
                     ARVFIDGSEPLPGLAP"
     gene            complement(11610..12380)
                     /locus_tag="ASD48_RS30305"
                     /old_locus_tag="ASD48_20715"
     CDS             complement(11610..12380)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020115646.1"
                     /locus_tag="ASD48_RS30305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20715"
                     /product="GAF and ANTAR domain-containing protein"
                     /protein_id="WP_242432772.1"
                     /transl_table=11
                     /translation="MARVRSDSRSARIQTLVAAQAARRGARVDVADVCTAAVAALPVGG
                     AGLSAMSRSAASHPLCSTDDISAQLEELQLTLGEGPCVDAFTQGSAVLASDLLTGAPPD
                     RWTVFADAALEAGARAVFAFPLQMGAISPGVLDLYANVPTVLDAEELADALAFADLATL
                     LLLDTQIYETGAPASEPLPDRGLEDLGGYRAEIDQATGILTVQLGVGIEEAFVRLRAHA
                     YTQGHRLADVAADVVAHRLRFSPETEPDHTGEED"
     misc_feature    complement(11838..11840)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(12368..13030)
                     /locus_tag="ASD48_RS30310"
                     /old_locus_tag="ASD48_20720"
     CDS             complement(12368..13030)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010986054.1"
                     /locus_tag="ASD48_RS30310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20720"
                     /product="hypothetical protein"
                     /protein_id="WP_242432773.1"
                     /transl_table=11
                     /translation="MSGQPMWGQLHKPHADSSAVDAVRLRRVNRWMAQGPAGELAHLYV
                     DSHKASDPEAYRSRSHQDYLNCLTGDIRRPTFAMVIAETDSLAECAIGFPVHSDGFWRL
                     GFDAALPLNIEQRIPSGAVFAITGILVSPYPHDEDVACRLQERLLRAHQASVGVTLVNQ
                     NDHPTLAALRSWGWLGMGEVWRPTEPPTFRALVLPLGERTAARLAGLVRDDWTRWPG"
     gene            complement(13027..13446)
                     /locus_tag="ASD48_RS30315"
                     /old_locus_tag="ASD48_20725"
     CDS             complement(13027..13446)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.4"
                     /locus_tag="ASD48_RS30315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20725"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_057604937.1"
                     /transl_table=11
                     /translation="MPVPQLTVYRQDRSYRAQITLAGEIDLESAPLVRASLRRCLHDGM
                     RTIDVDLAPVTFCDCSGLNAFLDAAQQTTMTGGTLRLHHPPPTLGLLLDLTGSRFLLLG
                     VPSRPLPPPPGDVPAPAALPHRTVAPAPALSGDVR"
     misc_feature    13962..13980
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.36"
                     /tool="antismash"
     gene            complement(<13995..14138)
                     /locus_tag="ASD48_RS45725"
                     /pseudo=""
     CDS             complement(<13995..14138)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010278077.1"
                     /locus_tag="ASD48_RS45725"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /pseudo=""
                     /transl_table=11
                     /translation="MQPEDVGLPRGQRRRTGGLRREEVAAPAGMSADYYSRIEQQRGPA
                     PSE"
     misc_feature    14711..14725
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.18"
                     /tool="antismash"
     gene            complement(14949..16196)
                     /locus_tag="ASD48_RS30330"
                     /old_locus_tag="ASD48_20740"
     CDS             complement(14949..16196)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129822.1"
                     /locus_tag="ASD48_RS30330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20740"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_057604940.1"
                     /transl_table=11
                     /translation="MLEQPHFGRQLRKLRLERGLSQAAVVGEGMSTGYLSRLESGERRP
                     TGRTVSYLAQQLGVDVAALTEPRAGGCLSRALAAATSAPPGTDSATALLQAVRDDEHDD
                     PVGRWQALWLLGRIRGGQGDFERERGHLRELIELSELIAAPDLRVRSHVQYARCLVALG
                     KARAAEPVAVTALAVARAEGLPTADVMAAQTVLIAVETGLGRLEAAERHVRELESELLP
                     TAAPQPAAEALWTASVVADRRGDHRTARSRLEAALALLRGGDDLILWTRLRTAATAAAL
                     QMSPPCVAAAERWLGEADVVLELIGTPIQLQEVRALRAHLAFHQGRLDEARTLCGALPP
                     DGELRLPHGDRVRLAVLEGRLMIMEGRVDQGVAALRRLGQQATDAHNLDLATHVWRSLA
                     TALADVHAPGVGGGVR"
     misc_feature    complement(16424..16437)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.55"
                     /tool="antismash"
     misc_feature    complement(16534..16550)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.86"
                     /tool="antismash"
     misc_feature    complement(16546..16557)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.52"
                     /tool="antismash"
     gene            16620..17270
                     /locus_tag="ASD48_RS30335"
                     /old_locus_tag="ASD48_20745"
     CDS             16620..17270
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129823.1"
                     /locus_tag="ASD48_RS30335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20745"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_057604941.1"
                     /transl_table=11
                     /translation="MSVVTTSITASSTTVVKAGAGVNRRRTYTAHVCPKGMTITAAEAD
                     FAAQFGASPGEICDRTLSDLLRAGTPELLRHRFTDLSEGRTSWFTERVAGRHDSGRVFA
                     ADLTAIAVTGATGPAGLVLLLSPLGAAGEPYPRELTLSELDVRVLEGVAGGASTVQLAG
                     RLYLSRQGVEYRVRLLLRRFDAPNRPALVARAHALGLFAPGQWPPRVLPELIE"
     gene            complement(17714..18232)
                     /locus_tag="ASD48_RS30340"
                     /old_locus_tag="ASD48_20750"
     CDS             complement(17714..18232)
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946493.1"
                     /locus_tag="ASD48_RS30340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20750"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_057604942.1"
                     /transl_table=11
                     /translation="MNNVSDIPTPLALLPRAQAGDEQAMNQLLTGIVPYVARLCRSITH
                     DDGADATQEALLAVYRGLRTLREPTAFYGWVRSVTVREAVRTLKRAGEEGPYQRVEPGQ
                     EANPLDAVHISDVLDRLSMSHRQVLTLRAYGLNEEEMARVLSLPVGTVRSRLHRARLRF
                     REAWQPSAA"
     gene            complement(18286..19575)
                     /locus_tag="ASD48_RS30345"
                     /old_locus_tag="ASD48_20755"
     CDS             complement(18286..19575)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Condensation_LCL (20-243). E-value:
                     3.9e-22. Score: 70.6. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30345_Condensation_LCL.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Condensation"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1127: condensation domain-containing protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004936278.1"
                     /locus_tag="ASD48_RS30345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20755"
                     /product="condensation domain-containing protein"
                     /protein_id="WP_057604943.1"
                     /sec_met_domain="Condensation (E-value: 2.6e-20, bitscore:
                     68.1, seeds: 42, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRALCPVETLYVGQRSRAVLSCTLRGRLDIEVLSAAFDAVTEAH
                     PALRTRIVPDGEGFALDLLDETARPRLSTRTGAAEDAYATELNTPLSVGGPLSRAVLVS
                     APEGDGHLFVLSVDHTVVDGHSGIALHNEIWERYRALAEGEERPGAADGVPGWAVPVSE
                     LLPAVDEAATSAYLERRVDEARRHPAELVAYDVTEPSAVEGRIEVCRLTLDEERTGRLR
                     RTARTAGVTVHALVAAALLTTARRRLPGGEPRALRCLSPVDLRSRLSPPLPALVMVPAV
                     TSHLQALDVAPESDPVELARTVHSRLGDFVAGDGPYHEMRITPEIPRNPTLQLATVIAT
                     NMGVVPGPRLPEGLEVTDVRLVPAREQYFPAAGRSPVMACVVSFEGRLAIEFPYFTACF
                     SPEFVRAFRDGVGAVLDACAAVEPVPTAAG"
     aSDomain        complement(18847..19515)
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30345_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="3.90E-22"
                     /label="ASD48_RS30345_Condensation_LCL.1"
                     /locus_tag="ASD48_RS30345"
                     /protein_end="243"
                     /protein_start="20"
                     /score="70.6"
                     /specificity="C activity: active"
                     /specificity="Active site motif: DHTVVDG"
                     /tool="antismash"
                     /translation="LSCTLRGRLDIEVLSAAFDAVTEAHPALRTRIVPDGEGFALDLLD
                     ETARPRLSTRTGAAEDAYATELNTPLSVGGPLSRAVLVSAPEGDGHLFVLSVDHTVVDG
                     HSGIALHNEIWERYRALAEGEERPGAADGVPGWAVPVSELLPAVDEAATSAYLERRVDE
                     ARRHPAELVAYDVTEPSAVEGRIEVCRLTLDEERTGRLRRTARTAGVTVHALVAAALLT
                     T"
     CDS_motif       complement(19417..19515)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30345_0001"
                     /evalue="1.30E-12"
                     /label="C2_DCL_024-062"
                     /locus_tag="ASD48_RS30345"
                     /protein_end="53"
                     /protein_start="20"
                     /score="40.0"
                     /tool="antismash"
                     /translation="LSCTLRGRLDIEVLSAAFDAVTEAHPALRTRIV"
     misc_feature    19761..19774
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.17"
                     /tool="antismash"
     misc_feature    19771..19784
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.89"
                     /tool="antismash"
     misc_feature    complement(19773..19786)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.62"
                     /tool="antismash"
     misc_feature    19997..20007
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 19.65"
                     /tool="antismash"
     gene            20001..28598
                     /locus_tag="ASD48_RS30350"
                     /old_locus_tag="ASD48_20760"
     CDS             20001..28598
                     /NRPS_PKS="Domain: Condensation_Starter (11-307). E-value:
                     4.4e-92. Score: 300.5. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30350_Condensation_Starter.1"
                     /NRPS_PKS="Domain: AMP-binding (466-877). E-value: 4e-108.
                     Score: 353.6. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30350_AMP-binding.1"
                     /NRPS_PKS="Domain: PCP (986-1054). E-value: 9.8e-21. Score:
                     65.7. Matches aSDomain: nrpspksdomains_ASD48_RS30350_PCP.1"
                     /NRPS_PKS="Domain: Condensation_LCL (1071-1370). E-value:
                     1.2e-93. Score: 305.4. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30350_Condensation_LCL.1"
                     /NRPS_PKS="Domain: CAL_domain (1830-2124). E-value:
                     2.8e-70. Score: 228.4. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30350_CAL_domain.1"
                     /NRPS_PKS="Domain: PKS_KR (2455-2632). E-value: 1.4e-45.
                     Score: 147.4. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30350_PKS_KR.1"
                     /NRPS_PKS="Domain: PCP (2750-2816). E-value: 3e-21. Score:
                     67.4. Matches aSDomain: nrpspksdomains_ASD48_RS30350_PCP.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters) NRPS:
                     Condensation"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129826.1"
                     /locus_tag="ASD48_RS30350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20760"
                     /product="non-ribosomal peptide synthetase"
                     /protein_id="WP_057604944.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-117, bitscore:
                     388.6, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="Condensation (E-value: 4.4e-57, bitscore:
                     188.8, seeds: 42, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 5.9e-42, bitscore:
                     139.1, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.3e-18, bitscore:
                     61.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLHEESLPEDERRPLSGAQEGLWYAQRLAPDSAAYNTAEAVEIH
                     GGLDTALFEAALRRTVGEAGTFALRFLDTDDGPRCRPAPDADDWPLHRVDVSDAADPEA
                     AAWKLIRADLATPVDTDKGPLFAHTLLTLAADRHIWLLRAHHLLLDGYSYKLLGRRLAD
                     VHNALAEGRDPGPGGFAPVGRLRTEEAAYLASERRDRDRDHWTRRLADLPEPARLTRRT
                     APPRAPFLRHTVELGAPDAEALSAAAAGLGITRADLLATALAVYLHRMTGMDDLVLGMA
                     TMSRLGSAALRTPGTASDVLPLRVTARPDTPLAEFARTVADELAALRRHQQYRGEFIRR
                     DLGLLGTGRRLHGPVLNIVPFTEELDFAGSAATWHHLSGGAVDDLQINVRPGTRPGALW
                     LALDANPHLYEEDELALHGERFLALLRRLAQAAPTTALADLDLLLPGEHPRDRPVREFP
                     VTGTLTELFERQVRARPGRIAVTHQGAHLTYGQLNEEANRLARLLVERGAGPGRTVALA
                     LHRGPRLLPALVAALKTGAAYLPLDPAHPAERLRLVMADAAPVLLVTEGGLAADLGGDV
                     TAVVLDEPAVTADLATRPASDLTDADRGGPIGPTQIAYVIHTSGSTGRPKGVPVPHSHV
                     VRLFAASAEHFDFGADDVWTLFHSYAFDFSVWEIWGALLHGGRLVVVPYAVSRSPRDFL
                     RLLHDEGVTVLNQTPSAFEQLVDADEEPTAGALRYVVFGGEALRPERLRPWTARHGLDR
                     PALVNMYGITETTVHVTHHRLTPDDLTDPRRGNVVGTPLADLRVYLLDPQGRPVPPGAV
                     GELYVTGAGVTPGYLHRPELTADRFLDDPHGPPGSRMYRSGDLARLRADGTLDHLGRAD
                     RQVQLRGFRVEPGEIEAVLAEHPGIARAAVVVRRADHGGEQLVAYLVTTGERPPAAAEV
                     RDHAAAHLPEHMVPAACVLMDTLPLTANGKLDTDALPAPDLTGAAAGTRPASTEQALVC
                     ALFEDVLKLPRETVGIDANFFDLGGDSLLATRLLARLRHGSGTDVPITALFAGPSPAAL
                     ARLLDGRPGTAPDRPALGERPRPERVPLSYAQERMRFLNRLDDSTATYNIPLVVPLGAA
                     ADTEALRAALGDLADRHEILRTVLADHDGTPYQRILPAGGPRPPLAAVDCPVDEIGAHL
                     AAASRHRFDLTGEPPLRAWLFGTGEDRTLLLLLHHSAADGWSLRPLADDLSRAYAARRA
                     GTAPAWDAPPPQYADYALWQRALLAPGPDGTGHAERLTAHWRQALAAAPQECTLPGDRP
                     RPTAPRDGAHVTEHVPAALHRDLTGLAEREGSSLFMLLHAAVSALLTRCGAGEDIVLGV
                     PVAGRSEPGLDDLIGLVTNTLVLRADTSGNPAFRELLARVRPGDLAALGHQELPFDRLV
                     DELNPPRRPGRHPLFQVMLALQNNEPAVLRLDGHATLLRPTATGTAKFDLFVDVLERHT
                     AEGTPDGLDLHIEYATDLYDPSTAEEFARSLGRLLAAVSADPDVRLGGLPAPAPRTPAE
                     APGPDTAGLTEAARSVPGIRDAVALTAADGGPPRLFVVPGRAEATEAVERLLERTGTPT
                     VGVTAVSTLPRDADGGLDPAALAALPAVDRAAAGAWQQRLARVTGVGAAEAGVEDTPRE
                     LARRHAAAPRRAAPASDGGTRGAAGTRPALSEGPEQAEPTVATWAQALVRAADHARGDI
                     VHVHPDGSETRREYASLVPEASRVLAGLRRAGLRPGDQVILQCDAGEDFLAVLWGCILG
                     GFVAVPLTVPASYDTPSAALTKLEGIWRMLGRPWIVCSPALEAGLRDRIGRDGGSGLRL
                     STADALRDAPEDRDWYAAQPDDLILMLMTSGSTGLPKAVRLTHRNVLARSAATEAMNGL
                     GADDVTLNWIPLDHVTGVVMFHLRDLYLGCRQIHAPTSWILQDPTRWMDLAHRHRVSVT
                     WAPNFAFGLLAGQAPRFADRDWDLTPMRLVMNAGEVVVAAAARGFLHALRPFGLPQDVM
                     HPGWGMSETCSVVTDAVLPAEPPGTDETFVSCGLPYPGFAMRVVGEDTTVLAEGEAGRL
                     QVRGTSVTGGYHDNPAANAEAFTDDGWFDTGDLAFLRDGELFITGRAKDVIIVNGVNHY
                     SHEIETCVEELPAVVRSFTAACAVRSDASAATDELALFFNLAPVPDRAAALREIAGKVT
                     REIGVSPAFLVPVGPGDIPKTEIGKIQRTKLRKSFEAGDFDDAVREAQLLLGTAATLPD
                     WFLKPVWQPAAPRAPRVLPPGRHTLVLACDGPWTHRLADRLARALRADGARCTVATDGP
                     SYERLDAARYRIRPAEDTDHTALLRDLAADERPVDAVVHLTAPHGGDAAPDESAARTLL
                     ALARALGTRPADLLHVTVDAQAVGAGEAPSPAQAMAGAVLKSLREESPGLRCVHLDVER
                     DTDPVPLVTAEAAQHLVDTEVAHRGGRRHVRRLAPLPEAPDRREPPATDGFHLVSGGLG
                     GVGGALAAHLLATPGARLLLLGRSPLPEDGGTHQRLRELGDVRYACADVTDEDQVRAAV
                     DEATEAWGVPLTSVWHLAGALVERPVGDLDPDAWRSALDAKAHGAWTLHRVSADHPVTS
                     FVLFSSVNGWFGGAMNTAYAAANAYLDALALHRRAQGLPAQSLAWSMWHERGMSSGYGL
                     TALTEARGYRVLDAAAALRSLDLARTLDEPHLLIGADRTAPWVRSHVAEPARQVRRLAA
                     RVALEEGADLGALHRAAADAAGVAPWVLRAAGSADRPEAADDTGGRIHVLEQRLAELWC
                     GVLHRDRVGRDENFFDLGGNSLLLVGAQSAVNQEFGCELTVVDLFAHPTVRDLARHLVG
                     RTTAPGTPTDAAGDPPSGLDRAKEQARRQRAARTRRSARNGKGQGHA"
     aSDomain        20034..20921
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30350_Condensation_Start
                     er.1"
                     /domain_subtypes="Condensation_Starter"
                     /evalue="4.40E-92"
                     /label="ASD48_RS30350_Condensation_Starter.1"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="307"
                     /protein_start="11"
                     /score="300.5"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHLLLDG"
                     /tool="antismash"
                     /translation="ERRPLSGAQEGLWYAQRLAPDSAAYNTAEAVEIHGGLDTALFEAA
                     LRRTVGEAGTFALRFLDTDDGPRCRPAPDADDWPLHRVDVSDAADPEAAAWKLIRADLA
                     TPVDTDKGPLFAHTLLTLAADRHIWLLRAHHLLLDGYSYKLLGRRLADVHNALAEGRDP
                     GPGGFAPVGRLRTEEAAYLASERRDRDRDHWTRRLADLPEPARLTRRTAPPRAPFLRHT
                     VELGAPDAEALSAAAAGLGITRADLLATALAVYLHRMTGMDDLVLGMATMSRLGSAALR
                     TPGTASDVLPLRVTA"
     aSModule        20034..23162
                     /complete
                     /domains="nrpspksdomains_ASD48_RS30350_Condensation_Starter
                     .1"
                     /domains="nrpspksdomains_ASD48_RS30350_AMP-binding.1"
                     /domains="nrpspksdomains_ASD48_RS30350_PCP.1"
                     /locus_tags="ASD48_RS30350"
                     /monomer_pairings="Thr -> Thr"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       20100..20219
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0001"
                     /evalue="6.40E-13"
                     /label="C2_starter_024-063"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="73"
                     /protein_start="33"
                     /score="41.3"
                     /tool="antismash"
                     /translation="AAYNTAEAVEIHGGLDTALFEAALRRTVGEAGTFALRFLD"
     CDS_motif       20430..20492
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0002"
                     /evalue="1.20E-07"
                     /label="C3_starter_134-155"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="164"
                     /protein_start="143"
                     /score="24.6"
                     /tool="antismash"
                     /translation="AHHLLLDGYSYKLLGRRLADV"
     CDS_motif       20823..20912
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0003"
                     /evalue="2.40E-08"
                     /label="C5_starter_265-294"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="304"
                     /protein_start="274"
                     /score="26.4"
                     /tool="antismash"
                     /translation="DLVLGMATMSRLGSAALRTPGTASDVLPLR"
     CDS_motif       20961..21074
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0004"
                     /evalue="6.10E-15"
                     /label="C67_starter_14fromHMM"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="358"
                     /protein_start="320"
                     /score="47.6"
                     /tool="antismash"
                     /translation="ADELAALRRHQQYRGEFIRRDLGLLGTGRRLHGPVLNI"
     aSDomain        21399..22631
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30350_AMP-binding.1"
                     /evalue="4.00E-108"
                     /label="ASD48_RS30350_AMP-binding.1"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="877"
                     /protein_start="466"
                     /score="353.6"
                     /specificity="substrate consensus: Thr"
                     /tool="antismash"
                     /translation="FERQVRARPGRIAVTHQGAHLTYGQLNEEANRLARLLVERGAGPG
                     RTVALALHRGPRLLPALVAALKTGAAYLPLDPAHPAERLRLVMADAAPVLLVTEGGLAA
                     DLGGDVTAVVLDEPAVTADLATRPASDLTDADRGGPIGPTQIAYVIHTSGSTGRPKGVP
                     VPHSHVVRLFAASAEHFDFGADDVWTLFHSYAFDFSVWEIWGALLHGGRLVVVPYAVSR
                     SPRDFLRLLHDEGVTVLNQTPSAFEQLVDADEEPTAGALRYVVFGGEALRPERLRPWTA
                     RHGLDRPALVNMYGITETTVHVTHHRLTPDDLTDPRRGNVVGTPLADLRVYLLDPQGRP
                     VPPGAVGELYVTGAGVTPGYLHRPELTADRFLDDPHGPPGSRMYRSGDLARLRADGTLD
                     HLGRADRQVQLR"
     CDS_motif       21588..21626
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0005"
                     /evalue="1.20E-03"
                     /label="NRPS-A_a2"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="542"
                     /protein_start="529"
                     /score="12.3"
                     /tool="antismash"
                     /translation="AALKTGAAYLPLD"
     CDS_motif       21837..21896
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0006"
                     /evalue="1.50E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="632"
                     /protein_start="612"
                     /score="26.8"
                     /tool="antismash"
                     /translation="AYVIHTSGSTGRPKGVPVPH"
     CDS_motif       22134..22223
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0007"
                     /evalue="2.60E+01"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="741"
                     /protein_start="711"
                     /score="-2.9"
                     /tool="antismash"
                     /translation="FEQLVDADEEPTAGALRYVVFGGEALRPER"
     CDS_motif       22422..22511
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0008"
                     /evalue="3.10E-15"
                     /label="NRPS-A_a6"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="837"
                     /protein_start="807"
                     /score="48.3"
                     /tool="antismash"
                     /translation="PPGAVGELYVTGAGVTPGYLHRPELTADRF"
     CDS_motif       22596..22661
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0009"
                     /evalue="2.90E-10"
                     /label="NRPS-A_a8"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="887"
                     /protein_start="865"
                     /score="32.2"
                     /tool="antismash"
                     /translation="HLGRADRQVQLRGFRVEPGEIE"
     aSDomain        22959..23162
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30350_PCP.1"
                     /evalue="9.80E-21"
                     /label="ASD48_RS30350_PCP.1"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="1054"
                     /protein_start="986"
                     /score="65.7"
                     /tool="antismash"
                     /translation="LVCALFEDVLKLPRETVGIDANFFDLGGDSLLATRLLARLRHGSG
                     TDVPITALFAGPSPAALARLLDG"
     aSDomain        23214..24110
                     /aSDomain="Condensation"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30350_Condensation_LCL.1
                     "
                     /domain_subtypes="Condensation_LCL"
                     /evalue="1.20E-93"
                     /label="ASD48_RS30350_Condensation_LCL.1"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="1370"
                     /protein_start="1071"
                     /score="305.4"
                     /specificity="C activity: active"
                     /specificity="Active site motif: HHSAADG"
                     /tool="antismash"
                     /translation="ERVPLSYAQERMRFLNRLDDSTATYNIPLVVPLGAAADTEALRAA
                     LGDLADRHEILRTVLADHDGTPYQRILPAGGPRPPLAAVDCPVDEIGAHLAAASRHRFD
                     LTGEPPLRAWLFGTGEDRTLLLLLHHSAADGWSLRPLADDLSRAYAARRAGTAPAWDAP
                     PPQYADYALWQRALLAPGPDGTGHAERLTAHWRQALAAAPQECTLPGDRPRPTAPRDGA
                     HVTEHVPAALHRDLTGLAEREGSSLFMLLHAAVSALLTRCGAGEDIVLGVPVAGRSEPG
                     LDDLIGLVTNTLVLRADT"
     aSModule        23214..28448
                     /complete
                     /domains="nrpspksdomains_ASD48_RS30350_Condensation_LCL.1"
                     /domains="nrpspksdomains_ASD48_RS30350_CAL_domain.1"
                     /domains="nrpspksdomains_ASD48_RS30350_PKS_KR.1"
                     /domains="nrpspksdomains_ASD48_RS30350_PCP.2"
                     /locus_tags="ASD48_RS30350"
                     /monomer_pairings="AHBA -> AHBA"
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       23280..23390
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0010"
                     /evalue="1.40E-10"
                     /label="C2_LCL_024-062"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="1130"
                     /protein_start="1093"
                     /score="33.6"
                     /tool="antismash"
                     /translation="ATYNIPLVVPLGAAADTEALRAALGDLADRHEILRTV"
     CDS_motif       23595..23660
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0011"
                     /evalue="4.90E-08"
                     /label="C3_LCL_132-143"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="1220"
                     /protein_start="1198"
                     /score="25.5"
                     /tool="antismash"
                     /translation="LHHSAADGWSLRPLADDLSRAY"
     CDS_motif       23709..23747
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0012"
                     /evalue="2.20E-05"
                     /label="C4_LCL_164-176"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="1249"
                     /protein_start="1236"
                     /score="17.0"
                     /tool="antismash"
                     /translation="QYADYALWQRALL"
     CDS_motif       24012..24101
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0013"
                     /evalue="1.10E-12"
                     /label="C5_LCL_267-296"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="1367"
                     /protein_start="1337"
                     /score="40.4"
                     /tool="antismash"
                     /translation="DIVLGVPVAGRSEPGLDDLIGLVTNTLVLR"
     CDS_motif       24162..24269
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0014"
                     /evalue="8.50E-19"
                     /label="C67_LCL_14fromHMM"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="1423"
                     /protein_start="1387"
                     /score="59.9"
                     /tool="antismash"
                     /translation="LAALGHQELPFDRLVDELNPPRRPGRHPLFQVMLAL"
     CDS_motif       25251..25289
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0015"
                     /evalue="2.70E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="1763"
                     /protein_start="1750"
                     /score="-0.6"
                     /tool="antismash"
                     /translation="WGCILGGFVAVPL"
     aSDomain        25491..26372
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30350_CAL_domain.1"
                     /evalue="2.80E-70"
                     /label="ASD48_RS30350_CAL_domain.1"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="2124"
                     /protein_start="1830"
                     /score="228.4"
                     /specificity="Minowa: AHBA"
                     /tool="antismash"
                     /translation="YAAQPDDLILMLMTSGSTGLPKAVRLTHRNVLARSAATEAMNGLG
                     ADDVTLNWIPLDHVTGVVMFHLRDLYLGCRQIHAPTSWILQDPTRWMDLAHRHRVSVTW
                     APNFAFGLLAGQAPRFADRDWDLTPMRLVMNAGEVVVAAAARGFLHALRPFGLPQDVMH
                     PGWGMSETCSVVTDAVLPAEPPGTDETFVSCGLPYPGFAMRVVGEDTTVLAEGEAGRLQ
                     VRGTSVTGGYHDNPAANAEAFTDDGWFDTGDLAFLRDGELFITGRAKDVIIVNGVNHYS
                     HEIETCVEELPAV"
     CDS_motif       25521..25574
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0016"
                     /evalue="1.80E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="1858"
                     /protein_start="1840"
                     /score="14.4"
                     /tool="antismash"
                     /translation="MLMTSGSTGLPKAVRLTH"
     CDS_motif       26136..26219
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0017"
                     /evalue="1.10E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="2073"
                     /protein_start="2045"
                     /score="21.0"
                     /tool="antismash"
                     /translation="GEAGRLQVRGTSVTGGYHDNPAANAEAF"
     CDS_motif       26283..26345
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0018"
                     /evalue="4.90E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="2115"
                     /protein_start="2094"
                     /score="9.8"
                     /tool="antismash"
                     /translation="TGRAKDVIIVNGVNHYSHEIE"
     aSDomain        27366..27896
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30350_PKS_KR.1"
                     /evalue="1.40E-45"
                     /label="ASD48_RS30350_PKS_KR.1"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="2632"
                     /protein_start="2455"
                     /score="147.4"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="FHLVSGGLGGVGGALAAHLLATPGARLLLLGRSPLPEDGGTHQRL
                     RELGDVRYACADVTDEDQVRAAVDEATEAWGVPLTSVWHLAGALVERPVGDLDPDAWRS
                     ALDAKAHGAWTLHRVSADHPVTSFVLFSSVNGWFGGAMNTAYAAANAYLDALALHRRAQ
                     GLPAQSLAWSMWHE"
     CDS_motif       27369..27464
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0019"
                     /evalue="5.80E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="2488"
                     /protein_start="2456"
                     /score="22.2"
                     /tool="antismash"
                     /translation="HLVSGGLGGVGGALAAHLLATPGARLLLLGRS"
     CDS_motif       27747..27848
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30350_0020"
                     /evalue="2.00E-12"
                     /label="PKSI-KR_m4"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="2616"
                     /protein_start="2582"
                     /score="39.6"
                     /tool="antismash"
                     /translation="FVLFSSVNGWFGGAMNTAYAAANAYLDALALHRR"
     aSDomain        28251..28448
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30350_PCP.2"
                     /evalue="3.00E-21"
                     /label="ASD48_RS30350_PCP.2"
                     /locus_tag="ASD48_RS30350"
                     /protein_end="2816"
                     /protein_start="2750"
                     /score="67.4"
                     /tool="antismash"
                     /translation="EQRLAELWCGVLHRDRVGRDENFFDLGGNSLLLVGAQSAVNQEFG
                     CELTVVDLFAHPTVRDLARHL"
     gene            28591..32469
                     /locus_tag="ASD48_RS30355"
                     /old_locus_tag="ASD48_20765"
     CDS             28591..32469
                     /NRPS_PKS="Domain: PKS_KS(Hybrid-KS) (17-446). E-value:
                     9.1e-154. Score: 504.3. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30355_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (545-827). E-value: 5.2e-82.
                     Score: 267.5. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30355_PKS_AT.1"
                     /NRPS_PKS="Domain: PCP (920-986). E-value: 5.3e-17. Score:
                     53.8. Matches aSDomain: nrpspksdomains_ASD48_RS30355_PCP.1"
                     /NRPS_PKS="Domain: Thioesterase (1014-1254). E-value:
                     3.6e-38. Score: 124.2. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30355_Thioesterase.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     hyb_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Thioesterase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129827.1"
                     /locus_tag="ASD48_RS30355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20765"
                     /product="type I polyketide synthase"
                     /protein_id="WP_057604945.1"
                     /sec_met_domain="ketoacyl-synt (E-value: 4.5e-62, bitscore:
                     205.3, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="hyb_KS (E-value: 2.4e-155, bitscore:
                     513.0, seeds: 33, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 6.2e-81, bitscore: 267.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.7e-12, bitscore:
                     42.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="Thioesterase (E-value: 2.4e-32, bitscore:
                     108.4, seeds: 16, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.6e-05, bitscore: 20.1,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHETDGPLDTPEEDLPAVAVIGMAGRFPGADDLDAFWDNLAAGRE
                     AVRPVSDEEFLAAGGDPRDLDDPSLIRMASVVEGIDRFDSGFFGYLPAEAAVVDPQQRL
                     LLETAYHALENAGRLAPGTDHGTFGVYAGAGDSRYYPAHLHPRHAGQPGSVELVHAATA
                     NSLGTLAPRISYELGLTGPSVSLQTACSTALVAVHTACQDLLDHRCDTALAAAVSLNPS
                     AALGYRHVPDGPFSPDGHCRAFAADAAGTSSGDGVGAVVLKRLADALADGDRVRAVIRG
                     SAVNNDGRRKVGFSAPSSAGQTEVVLAAQAQAMVDADSIGLVEAHGTATRLGDPIEVAA
                     LTEAFRESTRRRGYCALGSVKTNIGHLGAAAGIAGLIKAVLALEHRQIPPSLHFDRPNP
                     LIDFAAGPFRVPTALEDWPADGRPRRAAVSAFGIGGTNAHVVLEEAPASAPAPPRAPED
                     GGRLVLPLSARTVGALRGQAEALAHHLERHPDLRLDDVAHSLRTTRPALRHRLTVSAAS
                     REEALSALRAAAPATPTVPDEPARVAFLLPGGGTQYPGMGAELYRDQDVYRDTVDECAR
                     ILRPVLGTDLRTSLFEGTPADHTATFLGLVVTEYALARTLMAAGVRPDALIGHSLGEYT
                     AACLAGVIDLADMLPLVTERIRLISEAGGATVSVAAPAEEVLPLLDEELSLAAVNGPAA
                     CTVAGHEEAVARFERELARRDLPFRRVRIPAAAHSHVLDPVLETYERHLRGVTLCPPRI
                     PFVTSVTGTWITDAQATSVRHWLDHTRRTVRFTDAITALWERGRPVLVEIGPADTLTRL
                     ATTQLDPDTPVTVTTMRHAKADARDGFVLAEALGRLWSAGADTALPPVPGTPRPVPLPP
                     YAFERHRHWIDAPGARSTASDTSDTVRDEPHLAPRPRLTTEAVPPRTEREQAVARLWEQ
                     TLGIGGIGVHDNFFDLGGDSMRAVLLAGRLRRAGVLDVPAATLLAAPTVAGVLAATEDT
                     DDQRSGGTANALAPLLPLRREGGAAPLFCVHPGAGVSWRYTGLLPHLGGDQPVYGIQAA
                     GLDGTRPPAPDAPAMVASYVDLVREVQPHGPYRLLGWSYGGFVAHAMACALQEQGERVE
                     LLAMLDAPQPYSSAYDAETAERQVAALLMRVAGLPVPSDGEPPAVATVLDRIDAKVTAD
                     PAGSPVDRAQAAAVADVMRNNLRLAPRFEPGVFHGDVLFFSADDEPATDFAGDLAVQPG
                     KADAWRAQVRGTLHDHRVPCGHYEMTEPEPLALIGSAVAKALRGTADPTAPVPVPPPGG
                     PDRSGDPA"
     aSDomain        28642..29928
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: False"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30355_PKS_KS.1"
                     /domain_subtypes="Hybrid-KS"
                     /evalue="9.10E-154"
                     /label="ASD48_RS30355_PKS_KS.1"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="446"
                     /protein_start="17"
                     /score="504.3"
                     /tool="antismash"
                     /translation="VAVIGMAGRFPGADDLDAFWDNLAAGREAVRPVSDEEFLAAGGDP
                     RDLDDPSLIRMASVVEGIDRFDSGFFGYLPAEAAVVDPQQRLLLETAYHALENAGRLAP
                     GTDHGTFGVYAGAGDSRYYPAHLHPRHAGQPGSVELVHAATANSLGTLAPRISYELGLT
                     GPSVSLQTACSTALVAVHTACQDLLDHRCDTALAAAVSLNPSAALGYRHVPDGPFSPDG
                     HCRAFAADAAGTSSGDGVGAVVLKRLADALADGDRVRAVIRGSAVNNDGRRKVGFSAPS
                     SAGQTEVVLAAQAQAMVDADSIGLVEAHGTATRLGDPIEVAALTEAFRESTRRRGYCAL
                     GSVKTNIGHLGAAAGIAGLIKAVLALEHRQIPPSLHFDRPNPLIDFAAGPFRVPTALED
                     WPADGRPRRAAVSAFGIGGTNAHVVLEEAP"
     aSModule        28642..32352
                     /complete
                     /domains="nrpspksdomains_ASD48_RS30355_PKS_KS.1"
                     /domains="nrpspksdomains_ASD48_RS30355_PKS_AT.1"
                     /domains="nrpspksdomains_ASD48_RS30355_PCP.1"
                     /domains="nrpspksdomains_ASD48_RS30355_Thioesterase.1"
                     /final_module
                     /locus_tags="ASD48_RS30355"
                     /monomer_pairings="mal -> mal"
                     /tool="antismash"
                     /type="pks"
     CDS_motif       29131..29178
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30355_0001"
                     /evalue="1.30E-04"
                     /label="PKSI-KS_m3"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="196"
                     /protein_start="180"
                     /score="14.4"
                     /tool="antismash"
                     /translation="GPSVSLQTACSTALVA"
     CDS_motif       29557..29601
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30355_0002"
                     /evalue="1.30E-03"
                     /label="PKSI-KS_m5"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="337"
                     /protein_start="322"
                     /score="11.2"
                     /tool="antismash"
                     /translation="VEAHGTATRLGDPIE"
     CDS_motif       29662..29706
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30355_0003"
                     /evalue="2.10E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="372"
                     /protein_start="357"
                     /score="10.7"
                     /tool="antismash"
                     /translation="GSVKTNIGHLGAAAG"
     CDS_motif       30220..30273
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30355_0004"
                     /evalue="9.70E-04"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="561"
                     /protein_start="543"
                     /score="12.0"
                     /tool="antismash"
                     /translation="FLLPGGGTQYPGMGAELY"
     aSDomain        30226..31071
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30355_PKS_AT.1"
                     /evalue="5.20E-82"
                     /label="ASD48_RS30355_PKS_AT.1"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="827"
                     /protein_start="545"
                     /score="267.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LPGGGTQYPGMGAELYRDQDVYRDTVDECARILRPVLGTDLRTSL
                     FEGTPADHTATFLGLVVTEYALARTLMAAGVRPDALIGHSLGEYTAACLAGVIDLADML
                     PLVTERIRLISEAGGATVSVAAPAEEVLPLLDEELSLAAVNGPAACTVAGHEEAVARFE
                     RELARRDLPFRRVRIPAAAHSHVLDPVLETYERHLRGVTLCPPRIPFVTSVTGTWITDA
                     QATSVRHWLDHTRRTVRFTDAITALWERGRPVLVEIGPADTLTRLATTQLDPDTPVTVT
                     T"
     CDS_motif       30448..30567
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30355_0005"
                     /evalue="3.90E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="659"
                     /protein_start="619"
                     /score="57.6"
                     /tool="antismash"
                     /translation="GVRPDALIGHSLGEYTAACLAGVIDLADMLPLVTERIRLI"
     CDS_motif       30649..30687
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30355_0006"
                     /evalue="8.90E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="699"
                     /protein_start="686"
                     /score="9.5"
                     /tool="antismash"
                     /translation="AAVNGPAACTVAG"
     CDS_motif       30913..30945
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30355_0007"
                     /evalue="2.30E-02"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="785"
                     /protein_start="774"
                     /score="8.5"
                     /tool="antismash"
                     /translation="WLDHTRRTVRF"
     aSDomain        31351..31548
                     /aSDomain="PCP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30355_PCP.1"
                     /evalue="5.30E-17"
                     /label="ASD48_RS30355_PCP.1"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="986"
                     /protein_start="920"
                     /score="53.8"
                     /tool="antismash"
                     /translation="EQAVARLWEQTLGIGGIGVHDNFFDLGGDSMRAVLLAGRLRRAGV
                     LDVPAATLLAAPTVAGVLAAT"
     CDS_motif       31633..31662
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30355_0008"
                     /evalue="2.70E-03"
                     /label="NRPS-beforete1"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="1024"
                     /protein_start="1014"
                     /score="10.8"
                     /tool="antismash"
                     /translation="PLFCVHPGAG"
     aSDomain        31633..32352
                     /ASF="active site serine present: True"
                     /aSDomain="Thioesterase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30355_Thioesterase.1"
                     /evalue="3.60E-38"
                     /label="ASD48_RS30355_Thioesterase.1"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="1254"
                     /protein_start="1014"
                     /score="124.2"
                     /tool="antismash"
                     /translation="PLFCVHPGAGVSWRYTGLLPHLGGDQPVYGIQAAGLDGTRPPAPD
                     APAMVASYVDLVREVQPHGPYRLLGWSYGGFVAHAMACALQEQGERVELLAMLDAPQPY
                     SSAYDAETAERQVAALLMRVAGLPVPSDGEPPAVATVLDRIDAKVTADPAGSPVDRAQA
                     AAVADVMRNNLRLAPRFEPGVFHGDVLFFSADDEPATDFAGDLAVQPGKADAWRAQVRG
                     TLHDHRVPCGHYEMTEPE"
     CDS_motif       31813..31887
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30355_0009"
                     /evalue="5.90E-14"
                     /label="NRPS-te1"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="1099"
                     /protein_start="1074"
                     /score="44.3"
                     /tool="antismash"
                     /translation="QPHGPYRLLGWSYGGFVAHAMACAL"
     CDS_motif       32278..32301
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30355_0010"
                     /evalue="2.70E+01"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="ASD48_RS30355"
                     /protein_end="1237"
                     /protein_start="1229"
                     /score="-0.9"
                     /tool="antismash"
                     /translation="WRAQVRGT"
     gene            32472..33701
                     /gene="ccrA"
                     /locus_tag="ASD48_RS30360"
                     /old_locus_tag="ASD48_20770"
     CDS             32472..33701
                     /EC_number="1.3.1.85"
                     /GO_function="GO:0043880 - crotonyl-CoA reductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (44-396). E-value: 1.2e-19.
                     Score: 62.6. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30360_PKS_ER.1"
                     /codon_start=1
                     /gene="ccrA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639242.1"
                     /locus_tag="ASD48_RS30360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20770"
                     /product="crotonyl-CoA carboxylase/reductase"
                     /protein_id="WP_057605064.1"
                     /sec_met_domain="ADH_N (E-value: 1.7e-10, bitscore: 36.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.8e-20, bitscore:
                     68.1, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPQDLYELGDAPEPGTVPRKMYASLIRRERYGQPVDAFRTEVV
                     DVPPVRRGQVLVKVMAAGVNYNNVWAALGKPLDVIAARQKAGGVEDFHIGGSDLSGIVW
                     AVGEDVKGVRLGDEVVVLASRWDESAEDIRLGGDPAASVSQRVWGYEENYGSFAQFAVV
                     DDYMSHPKPARLSWAAAACYMATAATAYRQLFGWDPHTVRPGDPVLIWGGAGGLGSIAI
                     QLVRHVGGIPVAVVSSEERGAFCMRLGAQGWIDRRDFDHWGRMPDTSDDAAMSRWLSGA
                     RAFGRRFWDVLGERRSPRIVLEHSGADTIPTSLYLCDNAGMVVICGGTTGYNGDIDLRF
                     LWMRQKRLQGSHAACAREAREITRLIDRGAIDPCLSRTFGFDEIGLAHQLIHENRHPMG
                     NMAVLVNASE"
     aSDomain        32604..33659
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30360_PKS_ER.1"
                     /evalue="1.20E-19"
                     /label="ASD48_RS30360_PKS_ER.1"
                     /locus_tag="ASD48_RS30360"
                     /protein_end="396"
                     /protein_start="44"
                     /score="62.6"
                     /tool="antismash"
                     /translation="VDVPPVRRGQVLVKVMAAGVNYNNVWAALGKPLDVIAARQKAGGV
                     EDFHIGGSDLSGIVWAVGEDVKGVRLGDEVVVLASRWDESAEDIRLGGDPAASVSQRVW
                     GYEENYGSFAQFAVVDDYMSHPKPARLSWAAAACYMATAATAYRQLFGWDPHTVRPGDP
                     VLIWGGAGGLGSIAIQLVRHVGGIPVAVVSSEERGAFCMRLGAQGWIDRRDFDHWGRMP
                     DTSDDAAMSRWLSGARAFGRRFWDVLGERRSPRIVLEHSGADTIPTSLYLCDNAGMVVI
                     CGGTTGYNGDIDLRFLWMRQKRLQGSHAACAREAREITRLIDRGAIDPCLSRTFGFDEI
                     GLAHQLIHENRH"
     CDS_motif       33084..33143
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30360_0001"
                     /evalue="9.30E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="ASD48_RS30360"
                     /protein_end="224"
                     /protein_start="204"
                     /score="15.1"
                     /tool="antismash"
                     /translation="GDPVLIWGGAGGLGSIAIQL"
     gene            complement(33889..35367)
                     /locus_tag="ASD48_RS30365"
                     /old_locus_tag="ASD48_20775"
     CDS             complement(33889..35367)
                     /NRPS_PKS="Domain: AMP-binding (7-402). E-value: 2.9e-89.
                     Score: 291.4. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30365_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129829.1"
                     /locus_tag="ASD48_RS30365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20775"
                     /product="AMP-binding protein"
                     /protein_id="WP_057604946.1"
                     /sec_met_domain="AMP-binding (E-value: 3.5e-99, bitscore:
                     327.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLTQLLERNRQCFPGRTALVDEQRAVTWAGFHDRTLELARGFAE
                     LGIEHGDRVAVLSKDRIEVLETYFALARLGALFVPLNHSLAVPEVADIVARVGAVAVFG
                     ESELLDRQPELPASVRITMAFDKPAFEALGRVAARRELPPVADTDPVAVLHTSATTGRA
                     KGVTVDSASFRAIALGWLVQARPTDDIVMVNCCPLYHGSMVVSLTYMATGATIVLMPGF
                     TPQRALAAVERHRATHMWMVPQMVRFMLQAKGADRTDLSTLREILYGAAPMPLDVYEEA
                     VRRLGCGFRQVYGMTEVGGPFVTLGPDEHPSPGNATARIPCGRVIPGMSARAVGSDGTE
                     SARGEIGEIVVRGPGVMQGYWNDPQATREIDLDGWIRTGDLGFVDEAGRIHLVDRTKDV
                     IIRAGQNVYPSEIERALMSHPAVRDAAVVGMADEDYGEVPLAYVVAEPDTGARELLGHI
                     SGLLAPYKRPRRVEFIEQVPRNPAGKIVKKLLRT"
     aSDomain        complement(34162..35346)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30365_AMP-binding.1"
                     /evalue="2.90E-89"
                     /label="ASD48_RS30365_AMP-binding.1"
                     /locus_tag="ASD48_RS30365"
                     /protein_end="402"
                     /protein_start="7"
                     /score="291.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="ERNRQCFPGRTALVDEQRAVTWAGFHDRTLELARGFAELGIEHGD
                     RVAVLSKDRIEVLETYFALARLGALFVPLNHSLAVPEVADIVARVGAVAVFGESELLDR
                     QPELPASVRITMAFDKPAFEALGRVAARRELPPVADTDPVAVLHTSATTGRAKGVTVDS
                     ASFRAIALGWLVQARPTDDIVMVNCCPLYHGSMVVSLTYMATGATIVLMPGFTPQRALA
                     AVERHRATHMWMVPQMVRFMLQAKGADRTDLSTLREILYGAAPMPLDVYEEAVRRLGCG
                     FRQVYGMTEVGGPFVTLGPDEHPSPGNATARIPCGRVIPGMSARAVGSDGTESARGEIG
                     EIVVRGPGVMQGYWNDPQATREIDLDGWIRTGDLGFVDEAGRIHLVDRTKDVIIR"
     CDS_motif       complement(34261..34338)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30365_0002"
                     /evalue="7.50E-11"
                     /label="NRPS-A_a6"
                     /locus_tag="ASD48_RS30365"
                     /protein_end="369"
                     /protein_start="343"
                     /score="34.3"
                     /tool="antismash"
                     /translation="GEIGEIVVRGPGVMQGYWNDPQATRE"
     CDS_motif       complement(34861..34911)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30365_0001"
                     /evalue="7.20E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ASD48_RS30365"
                     /protein_end="169"
                     /protein_start="152"
                     /score="12.6"
                     /tool="antismash"
                     /translation="VLHTSATTGRAKGVTVD"
     gene            complement(35367..35621)
                     /locus_tag="ASD48_RS30370"
                     /old_locus_tag="ASD48_20780"
     CDS             complement(35367..35621)
                     /NRPS_PKS="Domain: PP-binding (2-71). E-value: 4.8e-12.
                     Score: 38.0. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30370_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946500.1"
                     /locus_tag="ASD48_RS30370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20780"
                     /product="acyl carrier protein"
                     /protein_id="WP_057604947.1"
                     /sec_met_domain="PP-binding (E-value: 8.7e-11, bitscore:
                     37.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVRELLVELTGTEEFADAARVGDDLDLASSGIDSGDLVRLVLL
                     VEQRAGVEITADDMERLQTIADYERFVAERSAAGAGGGA"
     aSDomain        complement(35409..35615)
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30370_PP-binding.1"
                     /evalue="4.80E-12"
                     /label="ASD48_RS30370_PP-binding.1"
                     /locus_tag="ASD48_RS30370"
                     /protein_end="71"
                     /protein_start="2"
                     /score="38.0"
                     /tool="antismash"
                     /translation="TVRELLVELTGTEEFADAARVGDDLDLASSGIDSGDLVRLVLLVE
                     QRAGVEITADDMERLQTIADYERF"
     misc_feature    complement(35726..35741)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.38"
                     /tool="antismash"
     gene            35944..37029
                     /gene="paaA"
                     /locus_tag="ASD48_RS30375"
                     /old_locus_tag="ASD48_20785"
     CDS             35944..37029
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129831.1"
                     /locus_tag="ASD48_RS30375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20785"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaA"
                     /protein_id="WP_057604948.1"
                     /transl_table=11
                     /translation="MSAAGPADTADAGEDELTARFEALVGAGEAVEPRDWMPDGYRRMV
                     LRQLAQHAHSEIIGMQPEGAWLTRAPSLHRKSVLIAKVQDEAGHGLYLYSAAETLGVDR
                     ADLLDALHQGRQRASATFDHPALTWADTGTIAWLTDGAAVINQAPLCRTSYGPYARAMR
                     RVCQEEAFHVRQGYDLMRALCEGTPAQKAMAQDAVDRWWLPAVALMFGPPDTEAGGADA
                     RTAAVGAAVSRRAMAWGIKRHTNDELRARFVDSCVPQAERLGLTLPDPAIRWNEERGHY
                     DFTPVDWDVYRRALGEDTHWARQRVAHRRAAHEDGAWVREAAAAYAARTRDDDGAAGQG
                     AGAHEYGHGQEHGHDRTEAGA"
     gene            37026..37391
                     /locus_tag="ASD48_RS30380"
                     /old_locus_tag="ASD48_20790"
     CDS             37026..37391
                     /EC_number="1.14.13.149"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129832.1"
                     /locus_tag="ASD48_RS30380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20790"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit B"
                     /protein_id="WP_079074063.1"
                     /transl_table=11
                     /translation="MSGGQPLGAPEARPVGAPEARTEGAPGSWEVFLRPRRGLSHQHVG
                     SVRAYDPDTALLRARDLYTRRGDPLSLWVVRSDAVHTASPDERDPYFANARHKPYRYPQ
                     QFAPLTTERSPDGGHDD"
     misc_feature    37044..37046
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            37396..38175
                     /gene="paaC"
                     /locus_tag="ASD48_RS30385"
                     /old_locus_tag="ASD48_20795"
     CDS             37396..38175
                     /EC_number="1.14.13.149"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129833.1"
                     /locus_tag="ASD48_RS30385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20795"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaC"
                     /protein_id="WP_057605066.1"
                     /transl_table=11
                     /translation="MAATEADGHTDPRLAVQLLRLGDDALVLGQRLCQWITRAPTIEED
                     LALSNIALDLVGQARLLLTLVGRLDGTGRDEDDLAFTRTDREFTNALLTELPNGDFAAT
                     VARQLVYTHYAVAYYKALGGCADPELAAFGQRAAKEIAFHRLHADTWTERLGLGTAESA
                     RRMQEGLDHVWPYTAELFDEDDPVRELAAAGTAPSPAPLRPGWERSTTEVITRAGLTVP
                     SPRWRARGGRAGLHTEEFASLVAELQSVRRQFPGGTW"
     gene            38172..38672
                     /gene="paaD"
                     /locus_tag="ASD48_RS30390"
                     /old_locus_tag="ASD48_20800"
     CDS             38172..38672
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129834.1"
                     /locus_tag="ASD48_RS30390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20800"
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaD"
                     /protein_id="WP_057604949.1"
                     /transl_table=11
                     /translation="MNGATALAASEIRARVEALPDPELPFIALGDLGVIGSVGPAADGR
                     LEVEFTPTYLGCPALAAIASSIREVLTDGGHPDARVRQVLSPVWTTDRVTAAGRAKLAA
                     HGIAPPAPASGDGPVLVRLTGVPCPHCGSRATRPHSAFGPTRCQSMLRCTACRELFPHL
                     SAL"
     gene            38669..39808
                     /locus_tag="ASD48_RS30395"
                     /old_locus_tag="ASD48_20805"
     CDS             38669..39808
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129835.1"
                     /locus_tag="ASD48_RS30395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20805"
                     /product="2Fe-2S iron-sulfur cluster-binding protein"
                     /protein_id="WP_057604950.1"
                     /transl_table=11
                     /translation="MRTRPNPVLAPDGTRRRTGWHRLPVTAVQHLTGDAVAVTLDVPDT
                     LRATFAHRPGEHVVVRHRRSGEELRRSYSVCPPPEEPGALRLVIKRGAPDGFGAYALTR
                     LAPGDRLELSAPAGAFALPELPGAHHVLIAGGSGITPLAAMGASALRTDPTCRVHLVHS
                     VPTAADALLADELALLKDAFVDRFTVLHLLTREGRPPLDGRIDAERLPRLLAALDVRPG
                     PDTTFALCGPAGLIATVRRALKDAGADPALVRSELFALGDTPPLPPVPSTPPVPGAVPG
                     APRTLEGTRVTALYDGHRRVVTAGPRDPALLDALLRDHPDVPYACREGICGSCRAKVLT
                     GEVATGPQYALDAGQLAAGYTLTCRARPLGGEVTVDFDA"
     misc_feature    complement(39852..39866)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.38"
                     /tool="antismash"
     gene            39860..40636
                     /locus_tag="ASD48_RS30400"
                     /old_locus_tag="ASD48_20810"
     CDS             39860..40636
                     /NRPS_PKS="Domain: PKS_KR (10-188). E-value: 6.6e-10.
                     Score: 31.1. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30400_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129836.1"
                     /locus_tag="ASD48_RS30400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20810"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_057604951.1"
                     /sec_met_domain="adh_short (E-value: 1.7e-31, bitscore:
                     105.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPLRHEGRTALVTGGSRGIGRAVARRLAGEGALVAVHYGHDHE
                     AAERTVKEIETDGGRAFPVHAELGVPGDADTLWTAFDHALAGQDAAPGLDILVNNAGIT
                     VPRRIADVTEDDYDRAFAINTRAPFFIIQRALDRLRDGGRIVNVSSVATRVAFPPIIAY
                     TMTKAALDYLTLALAQELGPRGITVNSVAPGYTETEINPTLAVPEIRRRYEAASVFGRL
                     GAPADIADVVSFVASDDARWVTGQWIDVSGGVHLGP"
     aSDomain        39890..40423
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30400_PKS_KR.1"
                     /evalue="6.60E-10"
                     /label="ASD48_RS30400_PKS_KR.1"
                     /locus_tag="ASD48_RS30400"
                     /protein_end="188"
                     /protein_start="10"
                     /score="31.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGGSRGIGRAVARRLAGEGALVAVHYGHDHEAAERTVKEIE
                     TDGGRAFPVHAELGVPGDADTLWTAFDHALAGQDAAPGLDILVNNAGITVPRRIADVTE
                     DDYDRAFAINTRAPFFIIQRALDRLRDGGRIVNVSSVATRVAFPPIIAYTMTKAALDYL
                     TLALAQELGPRGITV"
     CDS_motif       39896..39961
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS30400_0001"
                     /evalue="2.70E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="ASD48_RS30400"
                     /protein_end="34"
                     /protein_start="12"
                     /score="20.0"
                     /tool="antismash"
                     /translation="LVTGGSRGIGRAVARRLAGEGA"
     gene            40690..41535
                     /locus_tag="ASD48_RS30405"
                     /old_locus_tag="ASD48_20815"
     CDS             40690..41535
                     /GO_function="GO:0004833 - tryptophan 2,3-dioxygenase
                     activity [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_process="GO:0019441 - tryptophan catabolic process to
                     kynurenine [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946507.1"
                     /locus_tag="ASD48_RS30405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20815"
                     /product="tryptophan 2,3-dioxygenase family protein"
                     /protein_id="WP_057604952.1"
                     /transl_table=11
                     /translation="MNDGTSAPARAADDSLTRPFDGASPYDAYVHASVLNNLQQPLTEA
                     PDEMGFVVTTQVMELWFTLIVHEWRSAGTAFAKDDLDAAMDALARSRRALTALNAAWAP
                     LAALTPARFNGFRAAFGKASGFQSAMYRQLEFLLGDKSEAMLRLHRGDPDVHEALSETH
                     RQPSLYDEVLGCLHRRGLPVPEHVRERDVSAPYTSDPGVVEVWRLIYSGPQHHPLLGLG
                     ELLTDIAELVLRWRFDHVMVVRRAMGTKSGSAGSTGLAWLEQRANRPVFPELWEVRGGV
                     "
     gene            41525..42409
                     /locus_tag="ASD48_RS30410"
                     /old_locus_tag="ASD48_20820"
     CDS             41525..42409
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129838.1"
                     /locus_tag="ASD48_RS30410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20820"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_242432774.1"
                     /transl_table=11
                     /translation="MGSRVISAFAAEEEQRVLSLKPVLAPAHGRYGDHPHQAYDAWPAE
                     DPGAPLVILLHGGYWRYDRMHLTPFAAYLAEQGFDVLLPGFRRSGGAGGHPETFDDVAR
                     IVDTLPAGRPYLLAGHCSGGHLALWCAARGLLPAGSRWHTGTLPTGVLALAPITDLTAT
                     RRDGLSNDAALQLLGGEAVFEERLPAVDPLTLLRGAGTTGVPTVLLHGAVDEEVPLTQF
                     TDYAAVHEDLRTVVLPGTGHYTLIEPGAPGARAVADTLWEMSAGFAAPRDGTDAAPAHR
                     TDTGTAPGRATHP"
     gene            42406..43656
                     /locus_tag="ASD48_RS30415"
                     /old_locus_tag="ASD48_20825"
     CDS             42406..43656
                     /NRPS_PKS="Domain: Aminotran_5 (97-364). E-value: 1.7e-22.
                     Score: 71.8. Matches aSDomain:
                     nrpspksdomains_ASD48_RS30415_Aminotran_5.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139: aminotransferase class V"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669874.1"
                     /locus_tag="ASD48_RS30415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20825"
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="WP_057604954.1"
                     /sec_met_domain="Aminotran_5 (E-value: 4.2e-16, bitscore:
                     54.2, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAATPLEDRAALADAEDALAPLAERFVLPEGVIYLDGNSLGPLP
                     AAVPPALADVVARQWGTGLIGSWNDSGWWDAPLRIGDTIGRLVGAAPGQTVAGDSTSVQ
                     LFTALSAATALRPDRPLLVTDPGHFPTDRYLADAVARRGDALEVCRIPPADLEKFLAEQ
                     GPRVAAVSYSPVDFRTGELCDMAALTEATHRAGALAVWDLCHAAGAMPLHLDALEVDLA
                     VGCGYKFLNGGPGAPAWLYAARRHHDALDTPLTGWNGHASPFAMDRDYTPAPGIARARI
                     GTPPILSLLALEAALTVFEDVDLAQLRAKSVSLTEFFLACAEELLTPLDITPVTPRDAA
                     RRGSHVSLRHPHALGLTRALADRGVVIDMRAPDLLRFGVNALYTTHTELFTAAQRLSAI
                     VRESSYDPAPSRSGPVT"
     aSDomain        42697..43497
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS30415_Aminotran_5.1"
                     /evalue="1.70E-22"
                     /label="ASD48_RS30415_Aminotran_5.1"
                     /locus_tag="ASD48_RS30415"
                     /protein_end="364"
                     /protein_start="97"
                     /score="71.8"
                     /tool="antismash"
                     /translation="GDSTSVQLFTALSAATALRPDRPLLVTDPGHFPTDRYLADAVARR
                     GDALEVCRIPPADLEKFLAEQGPRVAAVSYSPVDFRTGELCDMAALTEATHRAGALAVW
                     DLCHAAGAMPLHLDALEVDLAVGCGYKFLNGGPGAPAWLYAARRHHDALDTPLTGWNGH
                     ASPFAMDRDYTPAPGIARARIGTPPILSLLALEAALTVFEDVDLAQLRAKSVSLTEFFL
                     ACAEELLTPLDITPVTPRDAARRGSHVSLRHPHALGLTRALADRG"
     gene            44075..46621
                     /locus_tag="ASD48_RS30420"
                     /old_locus_tag="ASD48_20830"
     CDS             44075..46621
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126302.1"
                     /locus_tag="ASD48_RS30420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20830"
                     /product="hypothetical protein"
                     /protein_id="WP_057604955.1"
                     /transl_table=11
                     /translation="MRLRQVSLVATLSLVAGLTTATVGLAGSAVYADDTAALPLSGYAH
                     LVVDPAHQHVFVSQGAGSTGIVVTDLSGTPITTVAGEQGAIGLALSPDGGTLYAALADG
                     GAIAAIDTATLSETARWSTGAGSSPVSVAVAGGRVWYGYTADGKGGIGSVDPSAPAPSA
                     VPQPGLSQWTTAPLLATGGDVLVAEEPQGNLSHVATFGVASGTASVKADTLVHGGTATG
                     LAVTGDGTGVLLAAPQQLALRAYRSTDLAAADPAAYFTGGSGSAPGSVAVDTDGTVAVA
                     GTSGVYLYAGPNTLAENHLTLPSGTVAPDGLEWGADGTTLYAVTKDSAGAYSLNVLGAP
                     KLTDSELALRHPQYAVPTERYTVSGLLSTRGLLPAGAALKVTRDGTALPDTTLGADGTF
                     TFTDLQQDEGTYTYQVAYAGDATHRSTAASLAVNVAKLPTDVVGTDITSANPGSVVLTG
                     RLMAQLGLGTFPQGTTVQVARRDESTQQTVPLGSVPVDPTTLRFTVTDAPGGAGSFMYV
                     FTYAGDATHQPSESGMSLVVAPYAPALTLSAPATAVRGAALSFGGKLGDGPYAAGRTVT
                     VSRKDAARSTPVTWTTPVAADGTVTVNNTPDIGGANTYTVTYPGDASHKAATAVATVQV
                     SRAATALTVTSSAPSYAYGATATVTAHLGTTYNGRTVSIHAMPYGGAKTLVTTGTVDAY
                     GNLKTTYKVTRNTTFTASFAGDYRYAPATATRAVNGYVKIATALGGYYTSTTYSGITYR
                     VFHKTVKPTVTATVTPNKAGQCERFEVQRYYSAAWHTLTTSGCYALSSASSAKAQLSLT
                     NALNQKFRVRPKYERSTKDLSNVSTWGGWLYFVVRT"
     gene            complement(47277..48014)
                     /locus_tag="ASD48_RS30425"
                     /old_locus_tag="ASD48_20835"
     CDS             complement(47277..48014)
                     /EC_number="3.1.-.-"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019056184.1"
                     /locus_tag="ASD48_RS30425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20835"
                     /product="dienelactone hydrolase family protein"
                     /protein_id="WP_057604956.1"
                     /transl_table=11
                     /translation="MTTITTRTVEYPADGLTMIGHLALPAGVDRRPAVLLGPEGMGLSN
                     VERRRADALAELGYVALAFDLHGGRYLGDPEEMLARCMPLLADPDRMRGIGHAALDVLR
                     TEPRTDPDRIAAVGYGTGGAVGLELGRDGVSLRAIGTVNALTTGRPGEAARIRCPVWAG
                     VGSEDPIMPPAQRNAFTAEMQAAGVDWRLAVYGGALHAFHHPPVHHPTVPGVGYHPQHA
                     QRAWRDVVDLLAECLPLTEDLRA"
     gene            complement(<48204..>48468)
                     /locus_tag="ASD48_RS45735"
                     /pseudo=""
     CDS             complement(<48204..48468)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011029008.1"
                     /locus_tag="ASD48_RS45735"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /product="ISL3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDPTVPVKHLFGEIRGQGFTGCLNRLHT"
     gene            complement(48832..49593)
                     /locus_tag="ASD48_RS30430"
                     /old_locus_tag="ASD48_20840"
     CDS             complement(48832..49593)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231: carboxyvinyl-carboxyphosphonate"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010072875.1"
                     /locus_tag="ASD48_RS30430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20840"
                     /product="isocitrate lyase/phosphoenolpyruvate mutase
                     family protein"
                     /protein_id="WP_057604957.1"
                     /sec_met_domain="PEP_mutase (E-value: 1.8e-60, bitscore:
                     199.9, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDSRTTVERAQRLKQLHAEYKPLVLPTVWDVWSARTAAAAGFPAL
                     TVGSHPLADSRGADDHEGQTFEEVLTAVRPIIAAVDIPVSVDLEAGYGQKPADLVAGLI
                     EVGGAGLNIEDTVHSDGGRVRSTQEHASYIAGLRGAADDAGVPVWVNGRTDLFLHAKDA
                     SGVLDEAIERLRALEQAGADSVYPVGIQDDDGLLAAVIGAVAVPVNSTAHPVKHDLERF
                     RRLGVGRITYGPLLQFAMTDAMKNMLGPWTP"
     misc_feature    complement(49561..49574)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            49850..50233
                     /locus_tag="ASD48_RS30435"
                     /old_locus_tag="ASD48_20845"
     CDS             49850..50233
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012784.4"
                     /locus_tag="ASD48_RS30435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_20845"
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="WP_057604958.1"
                     /transl_table=11
                     /translation="MPDLTWSRIDHPSDAVEGDQRITGEVITPQTRNGQVVISLKALPE
                     DPLVRFADLSGHVVNGTVTKIVPFGVLVWLAPGLEGLLHVSETTDPPVGSPDQLVSEGD
                     GITVRVAEADLQRHRVRLCIHDS"
ORIGIN
        1 gcgctctcgc cgacccgatc cgctgccgca tcctgctcgc cctgcgtgag gcgccggcct
       61 acccggccga cctcgccgac gcgctcggga tctcccgtac ccggctgtcg aaccacctgg
      121 cgtgcctgcg ggattgcggc ctggtcgtca ccgtccccga cggccgccgc acccgctatg
      181 agctggccga cgaacgcctc ggccatgctc tggacgatct gcgcgcggcc gtggtggccg
      241 tggagagcga ccgcacctgc ccggacgccg ccgacaaggg gtgctgctga ccatggccgc
      301 cgagatctcg atatccctcg gactgtcccc ggcccgccgc gaagcactcg ccaagcgcat
      361 acggctgctg gtcgccgcga ccatcaccta caacgtgatc gaggcgatcg tcgccctcac
      421 cgccggcacg ctcgcctcct ccaccgccct gatcggcttc ggcctcgact cgatcatcga
      481 ggtctcctcc gccgctgcgg ttgcctggca gttctccgcc cgcgaccacg ccgcccgcga
      541 agcacgcgag cagcgcaccc tgcggatcat cgcggtctcc ttcttcgccc tcgcggcgta
      601 catcaccttc gacgccgtcc gcgcgctcac cggcaccggc gaggccgaac gctccatccc
      661 cggcatcgtc atcgccgctc tgtccctggc gatcatgccg ttcctctcag ccgcccagcg
      721 caaggccggc cgcgaactcg gctccgcctc cgccgtcgcc gactccaagc agaccctgct
      781 gtgcacgtac ctgtccgccg tcctcctggt cggcctggtc ctcaacgcca tcctcggctg
      841 gtcctgggcc gacccgatcg ccgccctggt catcgccgcg atcgcggtga aggagggccg
      901 cgacgcctgg caaggcaagg ggtgctgcgc acctacagcc cacacgccgg cctccgtcgc
      961 agcagcggct gcggccgggg cggacgcgtg cggctgcaag ccgggctgcg cctgctgctc
     1021 gtgaacatct cgttgcggga tcccgatccc gccacccgct ccgtcgatac tgaccgggcg
     1081 atcacggagc ggcgggggca gcggtggagt ggacgatctg ggcggggttc gcggccggcc
     1141 tgctgatctc gacggtgacc gcgccggtcg gcgtgtccgg ggcggtcttc ctcctccccg
     1201 ttcagctcag cgtcctcggc gtgcccagcc cggcggtcac tccgacgaac ctgctgttca
     1261 atgtggtggc cgggccaggc gcactgtggc gctaccgccg tgacggcgct ctgcgcggcg
     1321 gcctggcccg gcgcctcgtc gcatggacac tgcccggcgt catcgccggc gccgctctcc
     1381 gcgtcttcgc cctccccagc cccggcgtct tccgcatcct ggtcgccgcg ctcctgctgc
     1441 cgctcggcgc gtggctgtgc ctgcgcaccc tgcgccccgc ccggccacgg gcggacgcgg
     1501 ccgaaccgtc ggcgcgcgtc ctcgccgctc tcgccctggc ggtcggggtg gtcggcggga
     1561 tctacggcat cggcggcggt tccctgctcg ggccgatcct tgccgcccgc ggcatgccca
     1621 tggcccgcat cgcaccggcc accctcgccg ccaccttcac gacctccctc gccggggccg
     1681 ccgcgtacgc cgcgctggcc ttggcgagtc ccgggcccgt cgcgcccgac tggcggctgg
     1741 gtctggcctg cggcgccgga gggctgatcg gcggctacct cggcgcacgg ctccagcccc
     1801 gccttcccga aaccgcgctc cggctcctgc tcggcgccct cgcctccgcc ctcggcgcgg
     1861 tgtacgccgc ccaggccctg acctgatccc caaggcggcc ggctgaggcg aggaaggacc
     1921 cgccagccca aacccgcgcg ctcgtccata tctgagcgcc gcacacgatt cggttccggc
     1981 gtcaccatgt ccgggaatcc ccgaacccgc gcgcttccgg ttgtacgagt tcgatgcagc
     2041 tttaccgcga actgctcgca ctcggccaca ccggcggtta ccacgtcgtg aaccgctacg
     2101 tgaccaccgt caggcagggc accgtgatcc ccgcgcaggc agcgactccc agccctcgca
     2161 ccatcacgtc acggatcatg cgccctcaag aggcactcag tccctccgac accgctcaac
     2221 tggaagctgc aagaaacgcc tgcccagaga tcaccaccgc ctgcgacttc gcacgggagt
     2281 tcacggccat ggtccgccac cggcaaggcc atctgctccg aggctggatc cgaaaggccg
     2341 agctgagcgg ccccgcagcc ataggcgtct tcgccgactc catccaccgg gaccctcgac
     2401 gccgtcaccg ctggcctctc cctgccctac agctccggcg tcgtcgaggg ccacgtcaac
     2461 agaatcaaaa cgatcaagcg ccagatgtat ggccgcgcct ccttcaacct gctcaaggcc
     2521 cgcatcctcg tccaaccgta gccatcacgg atgcgcggtc agaacccgcc ggtaggccac
     2581 tctgagcacc gcagttggcc actgctttct ccccggctgg aacggggaga aagcagtggg
     2641 cggatcagcg gagtgagaag gtctcagtgc tggatcagta gttcgcgcag tagtcggaag
     2701 acgttggcgg tagccgagac agcagccgga atcacacccc accagggctt cgagttgcgc
     2761 tgctccctgt gccgcgaggt accgtcaggg gacacgatgc atcacctctc ttatggtgat
     2821 cttcggtgcc cgtcggggcg agtcgaagct gtccaggccg ctcgcgccga cgggcttctt
     2881 gttgccctct atggaatcaa gagatcggcg gttcgcaaat tcgatccagg atttccaagc
     2941 atcgattggc ttgccccgcc cggggggtgt gacctgcgtt actgacccgg tggttggtca
     3001 ggtcgggggc tcggcaaact cgacggccga ctcctccacg tcctccgttc cgcggcaggc
     3061 agttcccgga ccaacaacgc agcgggcagg aagggacctg ccggaacagc cgccccggtt
     3121 gaggcgggct ccatctgcta cgtcagcgtg ggcgcgacag tgtgtgcgag cgagggaacc
     3181 gctgaatcga ttccggccac tttcggagcg tgcggtgcgt tcagagcgtc cggctttccg
     3241 gccagtgcgt cttgctcgat aacatcgcaa acccccatgc cattctgcgc cgctggcagg
     3301 gtcgccccca tgtacacgca cccacgagga gatgtccaac attgtcctgc ggagattcct
     3361 ggcgtccgtg gggtttcggt aggcctccta cttgatagca aagttggctt aaaaccgcct
     3421 cggggtgcag catgccccag cggctgcggt cagcgtgacc gacgggaggc cgggaaggcc
     3481 tctgctgagc gcagagtggc caacggcacg tcagcaaact gcgagacgat caggcggaca
     3541 tcccgctcga gttcagggga ctcgctccag acttcgcgat ccatgcagcg gcgatctcca
     3601 acctggtcgt gaagacgtcg cagctgatcg agaccgggat tcctgcttcg tggcgtgtcc
     3661 agcaaccagg caagacccca ccgctggcgg gtcatagcgc ggccgtgaat cggatgccgc
     3721 tgatgggtag tctgccaaca cagggtgggg ggaacggttg tggtgaggct acggggggca
     3781 gcgctagccc ttaccgtcac ggttgttgta tcaactgcgt tgctggcatt ggccagtaac
     3841 gcggcgacgg gggacaatcg ttggccgggc gtcctggacc agttgcgaga gcacgcatgg
     3901 cccgcggtcg ctgtgctact cgtcgtaggt gtcggcgcct cggtattgct gactgctgtc
     3961 gcgaaccaaa tctccgccgc cgaggaaggc cctccagctc ccagtccgtc aggcgtaccg
     4021 gactgggtga ttgatcgcgt tcagacgcag caggccatcg ctgccatatg tggtcgactt
     4081 catggggcca tgcctaccgt cactgccctt gaaggagcgg gcgggttcgg caagaccaca
     4141 ctcgcggacg tagtgtgcgc caaccggaag gtgcggcgac gattccgcgg ccggatctac
     4201 cgggtcaccg taggacggga tgttcgtggg cgcgcggcga tcgcggccaa ggtaggtgag
     4261 gtcacacgct tcatcacagg taatgccgag gcgtttgagg accccgagct tgccggtgca
     4321 cacctgggac gccttctgca gaaacgcccg agaatattgc tcgtgctcga cgacgtctgg
     4381 gacgcggagc aactcaggcc gttcctgatc ggcggcggga attgcatccg gcttgtcact
     4441 acacgccggc aggatgtatg tcctggcacc gccaggcgca tcttggttga cgagatgtcc
     4501 gcgccagagg ctcgcagagt actgaccagg gacctcgcgc cgttgccgca cgagaccgtc
     4561 gagagcctcc tggaagccac gggtcattgg ccactactac tgcgtctcat caaccgtgtg
     4621 atattcgccg aagcgactct gacctgcgga gaatcggctc gtgcggcggc aaccacggcg
     4681 gcaggagcgc gcgtattgca gcagctgagc gaaaccggtc cgactgccgt cgacgatccg
     4741 tgggaccctc cggatctgaa cgacccggta caccggacca aggctgttcg ggccactatc
     4801 gaggccgccg tacaactgtt gccagaaaac ggcgcggaac gattgaccga actatgcgtt
     4861 ttctccaccg acgatgctgt cccgctgtca ttggtcgaaa cgctgtggcg gaaacaggcc
     4921 gggctgagca ccaccgaatc gcaggccctg ctgcgaagga tcacaagtct gtccctcgcg
     4981 aacccggtct accaagagac aggagcactg gcgctgcacg acgtcgtgcg cgactatctg
     5041 cgtgcagaat taggccctgc gcacctcacg cagctgcacg agtcgctcgt cgatgccgtg
     5101 gccggccaaa tgccgtccgc aagccagctc ctcccggatc gagccgctcc cagtagatcg
     5161 tggtgggcgg cggagcacgg ctacctgctc gatcacgtca tcgatcacct tctggcggcc
     5221 gggcggaacg ccgaagccga agccaccatc agcgatatcc gctggattga agcacgcctc
     5281 ctgcaccagg ggcctgctgc gacgcagaac gactgcctcc gagtcgccac cgagtcatcg
     5341 atacagcgaa gccgtgatat tggccgcatc gcgcacctct tggcgccgac cgacccccca
     5401 gaggctgtcg tcggcatcct tcacgagcgc ctatttccca tccccgcttg gcaagacgag
     5461 atcaccgcgc ggcgtgcaga acgccttgct tcggccctga tcgatgatgg agacttgcct
     5521 gatctgcctg atccttcctc ggaacgcact cttctgggcc acaccgatca ggtgctctct
     5581 ctggcgtttt cacccgatgg cacacggctc gccagcgcgg gcgacgacgg cttcatccgt
     5641 ctctgggacc ttgaatcagg tagcaccgct cacgccatca aactcagatt cggatcgctc
     5701 aaccggatcc gagtcctggc ctactcgccc gacggaaccc agctggccgc cgcagggtcc
     5761 ttcggagtca ggctctggga cctgacggct tacaccgcca cccgctccct gccccgccgc
     5821 cacgccggca agacccgtga cctcgcgtat gcgccggacg ggacccaact cgccaccgtc
     5881 ggccacgatg acaaggttcg gatctggaac ccggccaccg gcaagatcac cgctgtcctc
     5941 agcggacaca cgggccgagt ccgcgcactg tcctacacgc ccgacggccg gaaactcgcc
     6001 accatcgccg acgacggaac gatgagggcc tgggatcccg tcaccggagc aaccctcgcc
     6061 gcagcgcacg gaagcgcctg caaacctcgc ttcctggcca cctccaactc gcattacgtc
     6121 gtcgccggaa acagaacccg tgaggatccg ttcgtagaaa tccatcacag agccacgggc
     6181 gaactggtgc acgagatccg tctcgactcc agcagactgg aggcaacggc gtactcgccg
     6241 gacggcgcgc aactggccac ggcgggcgct gacgggacag tgcgactctg ggagactgct
     6301 acgggcgccg ctgtccatgg ggtgcaccgg cgccttggcc gtgtaatggc cctggcctat
     6361 tcccccgacg gaatgcgcct cgccagcgcg ggagcggaca atgcggtgcg cgtctcgaat
     6421 ccccacgccg actccagcga gttgcgcttc gcagccgcgc ggagcctcga cctctcacgg
     6481 gacggaaatc gagccgccat cgctctctcg gacaaaagag tattgatcat tgagactggc
     6541 tccgatgggt ggcgcgacta cacgacgcgt agcattacca ttcctgaaca cgccgtctgg
     6601 cggcttccgg tcgctgtgtc cccggacgga gcccatatcg ccaccggtgg cgccgaggac
     6661 catgccatcc ggattcggaa ccagcaggcc ggcgacgtga ccgacactct ctccggacac
     6721 aggcggaaaa ttcgagcgtt ggcgtactca ccggacggga ctcaactcgc ttcgggtgcc
     6781 agcgacggcg tgcggctctg gcagctggcc tctggggcgt ccaagcttcg tctcataggc
     6841 ggtaacgtgt tggcgtacgc ccctgacggg gacgaactgg ccactgctgg cggtttcggt
     6901 ctcctcgtct atttgttgga tccggtcacc ggccagcgta aagggctcta taagcagccc
     6961 gagagtgtgt gcgcgcttgc gtactcgccc gacggagccg aactcgctgc aggtctcgag
     7021 aacggccggg tgatcgtacg ggaccggaca accgcccaca cccaactcca ttccttcggc
     7081 gcccatgccg cagcagtgaa cgctgtctcg tactcgcccg acggcctcta catagcaacg
     7141 gccagcgcag acctgtcctt gcggatttgg ggccgccaag gcactccggt caccatgacg
     7201 cgaaccgagc aggccctcga atccctggcg tgggtcgcgg acgcctccgg tcgcgtcatc
     7261 atcggcggtg gtgggggcgg ttggtacgtc tggaagttca aagcagtcaa cacccgctag
     7321 gtgagggttc ggttctccgt tgcccgtttc atttgattct ggatgttcgc aaccccgccc
     7381 ccttgcggcc gcacccgagc cggcggcagc aggggcctca ccagctccca cagtccgtcc
     7441 ggaacgatcc acccccaccg cccctcccca tgaccagtac agctgctaac tgaccatgta
     7501 ggacacggtc ttagggttcg tgccacgggg ccgggcttca tcccacccca gccgcaccgc
     7561 agggggaccc cgatacgaag tgtcgcaatc tcatcggcgg tttcgctgtc gccgcaacag
     7621 cagccgccgc ccccggcagc acaggaaccc gtcgtatcgg catgtgcgac gccggccgcc
     7681 tacaacagcg cttcgccgag gtcatcgcga gtgaccaccg ccacggcggt caactcggca
     7741 tcgagcagcg cgccgccgcc ctcgccgagg aggcgctgaa cctatagaac gccggcagcg
     7801 ccactcaacg cgtgcgcagt agcttgtacg gatgcgctgc atcgttccgc tcctctgcga
     7861 tgcgggcagc gatcgacggc cgccgctacg gcgacgcgaa ggcacacgtg cgcgaggccc
     7921 aggccctcgc cgagatgtcc ggagaccagg ccgtcaagtt ctgcatctgc cgccatgcgg
     7981 ggccatgtac cggtacgtcg gccgtccggg ggaggccctc gccgcgaacg atgtcgcacg
     8041 caacctgcgc ttcctggaca gacgtcaagt ggccatccgg tcccccgcgg aggcgctgac
     8101 gtgggccgct gtccgcaacc tctgaggggc gctacgctgt tggtacggcc ccagaccccg
     8161 gcagtgatgc ccttgttccg ctccggggag gcccaccgtg ttcgttctgc ttctcatcct
     8221 cgtcgtcatc ttgttcggcc tcggcttcct caaccccatc tggtgggtgg ccgcggcggt
     8281 gttggtcttc ggtgccaacc gtcacggtcg cgatcgcggg ggaggctgga tccgtgacga
     8341 cggttccgat ctcggggggt accgggacta cgagaaccgc cgggatcgtc aggaccgctg
     8401 ggaccgtcgt tacagccgtc gcaaccgggc gcgctggagg cgcgaggacc gtcgggacca
     8461 tgaacgccgc gggtgagcga tgaagttgcc cgacatccag aggctccggg acggcttcag
     8521 ccacgccgga cgctctgaaa atcgtggaga ggtagatgcc atgcatcgca caaccgtgct
     8581 cccggagaat tggtgggatc tggcagtcga ggccgcggca gggaacccgg gaggtcagga
     8641 tgtcgtcgcg ctgcgcgccg agaacgatca actgcggcgg gcgctggctg gccgtgcggt
     8701 catcgatcaa gcctgcggca tggtgatggt cctggcccca tgccgtcgtg ggacggccag
     8761 gggtctgctc gtggacatcg cgcggcagtg caacaccaag cttccggagg tggccgcggc
     8821 catggtcgcc gcctgggaag gagtgcccct ctcgtggccg atgcagcagg cgctacggcg
     8881 tgccctgcgg cggctttatg cggaagaccg ggggtgcggt tcaccactgg cggatgagcg
     8941 gtccggaaag ggaaggccgt gatccacgca gcggatgtct gcgagtggcg aaaccgcgac
     9001 atcgtggaca ccgattcgca caagatcgat gtcttgggga cggtccatgc gggcaccacc
     9061 accgacgagc cagccgtggc cacggtacgg actgacgacc cggcaccgcc tcgctgatgc
     9121 atggatacgg gtcctcaccc tgggccgttt ccgtggactg ctccgccgtc gctgtccatg
     9181 ctgcgtagta cagcagcagc ctggccatga agttgatcca cagcacgtcg gcgaccggct
     9241 ccgcccggcc agcagcttgc gctggtcgag gacggcgctg agcgaggcgg cgaggctcgg
     9301 gacgatcagc gtggccgcgc cggtgccggg gacggtgacg gtctgttcgt ccagagtggt
     9361 gaagatgtcc tcgacgagcc gctcggccat cctcggcgcc ttcggccgta acagggtgac
     9421 cagtcggtgt cggccggctt cgcggatctg ggccggtgac ccgaaccgtt ccagcagcgt
     9481 gaggacggcc gggtgctgga gccgaggtcc cagcacccgt tccgaggagg ggtggatctg
     9541 ggtcagcagg ccgttaagcc ggttcgcgat cctggtggct tcgccggcca ggtcgtcgtc
     9601 gatgcccacg atcatctcca gctcggcgat cgtctcgtcc tcgccgacga tggcccgcag
     9661 ggtgttgggg catcgcgcgg gccgcgtcag cgatgatgaa cgcgtccctc gcgtccgtct
     9721 tggcctcacc tactgaagag ctcgtggagt ttgggttcgg tggtgggcag gcgcttgtcg
     9781 aaggccttcc ttccggccgg ggtgacggcg gtggcgtggt gttcgcccct gccgacgtcc
     9841 aggccgagga agacgacgat gtcgccggtg tcgatcacgc gcaggcccct tcatcacgct
     9901 ttcgcccggc cctgccaggg catcgagctg cacatccacg ttacggagag ctcttccggc
     9961 tcgggtgaag ccgctgctca agcccctcat cagcggtccg tcgatgcgtt cggacccggt
    10021 gacaccaccc ccggatcatg aacaacaagg ggggaagtca tgccggcccc gaaggccgga
    10081 ggccccatta acggagccac gaaaagggta acggggggct gaaagcaggg accgcaccgt
    10141 tcgggagtca ccatcgacgg gcggatctac cctgggacac gggcggccgt atcacaccgc
    10201 aagaatcgaa ggacatcatg atcgtcctcg gaatcacccc ggggatcctg ggatccgtcg
    10261 gacacaaggc cgccggacgg cggcactcct ggaagcagcc cctgcccagc ttgggcaaca
    10321 acccgttctc gcacgacccc cgaccccgag cacgcgtaca gcacgcggcc gtcacaaccg
    10381 tcctgccgcg cctccggcac gcgcaactcc gaaccgaggc agcacgccat ggccctcttc
    10441 tacctcctgc tgatcgccgc gatcgtgctg gtcatcgtcg gtgcgaccgc cgaaggcatg
    10501 ctgtacttgc tctccgccgg ggtactgctc ctcatcgccg acgtgctcta ccgcgccgtg
    10561 agatcggtac tgcaccagcg tccggcccac tgaccccgcc ccgcgcgcat cagccgctgc
    10621 tccctcgcgg gtgatttcgc tgatgaggcc gtggccgtcg ggaccggcca ccatcagtac
    10681 cagcacgacg gcttccctgc tccctgctcc ctgcgctcaa gcgcgccgga gggcggctct
    10741 tgtgccgacg gcattggaac aagtctgggt cttccgtgga tgccgtctcg tgcgttcgcc
    10801 atctcggcga tgtctcaggg cgccaggccg gggaggggtt cggagccgtc gatgaagacg
    10861 cgggccaggt cggacaggcg ccggttgtgg gcgcgggcgt agccgcgaag ggcggtgaaa
    10921 gcctcttcca tgtcgatgcc ctggcgttcg gcgagtttgc ccttggcctg ttcgatcagc
    10981 acgcggctgt tcagggcggc ctgcagctgt tcgttgagga cagtgctgcg ctggctggaa
    11041 cgttgttgca gcaggctgat ggtggcgacg tcggccagcg cctgggcgat gagggtgccg
    11101 gccgggtcga acgggccggg ggcgacgcgg aagaggttca gggcgcccac ggtttcgtcc
    11161 cgcaggcgca tgggcaaggc ctggaccgcc tcgaatccgc tgcggtgggc cgccgtgacg
    11221 aagcgcggcc agcggtcggc ctcccgggtc aggtcgggga tgatcacagg cgtgccggtg
    11281 cggaagcact ccaggcaggg gccttcgtcg ttctggagct ggaagagttc cagcagccgc
    11341 acatgttcgt tggaggcggc catgacgcgg agtttgccgt cccggtcggc gagcagcacc
    11401 ccggcggcgc tcgcgtcgag catgccgacg cagcggtcgg tcagcaggcg caggaaatcg
    11461 atgaggtcga agtcggcgac caggttgtcc gccagctcga cgaaggtctt ggccaggagc
    11521 tgctgattca tcgtgacacc ctcgattgag actagtcccg ccgggaaggg gcgggaagcg
    11581 cagcacgttc atcggatggc accggtgcat cagtcttcct cgccggtatg gtccggctcc
    11641 gtctccgggg agaagcggag tcggtgggcc accacgtcgg cggccacgtc ggcgagccgg
    11701 tgcccttgcg tataggcgtg ggcgcggagc cggacgaagg cttcttcgat gccgacgccg
    11761 agttggacgg taagaatgcc ggtggcctgg tcgatttccg cccggtatcc gcccaggtcc
    11821 tccaaaccac ggtccggtaa tggttcgctg gccggcgcgc ccgtctcgta gatctgtgta
    11881 tcgagcagga gcagcgtcgc gagatcggcg aaagccagcg cgtcggccag ctcctccgcg
    11941 tccagcacgg tcggcacatt ggcgtacagg tccagaaccc ccgggctgat cgctcccatc
    12001 tgcaagggga aggcgaagac cgcgcgtgct ccggcttcca gggccgcgtc ggcgaacacg
    12061 gtccagcggt ctggcggtgc tccggtcagc agatcggacg caaggacggc cgagccctgt
    12121 gtgaaggcat ccacgcaggg cccctcgccc agtgtgagct gaagctcctc cagctgggcg
    12181 ctgatgtcgt cggtgctgca caacggatgg ctcgctgcgg acctcgacat cgccgacagc
    12241 cccgccccac cgaccggcag cgcggccacg gccgcggtgc acacatcggc cacgtcgaca
    12301 cgggcgccgc gtcgggccgc ttgcgcggcg accagcgtct ggatgcgggc cgaccggctg
    12361 tcggacctca cccgggccac cgggtccagt catcgcggac aagtcccgcc agcctcgccg
    12421 cggttctttc cccgaggggg agtaccagag cccggaacgt ggggggttcc gtcggccgcc
    12481 agacctctcc catgcccagc catccccagg agcgaagcgc agccagggtc gggtggtcgt
    12541 tctgattcac caaggtgacg ccgacggacg cttggtgggc gcgcagcagc cgctcctgca
    12601 accggcaggc cacgtcctcg tcgtgcgggt acgggctgac caggatgccg gtgatcgcga
    12661 agacggcccc ggaggggatg cgttgctcga tgttcagtgg caatgctgcg tcgaaaccga
    12721 gccgccagaa gccgtcgctg tgcacaggaa atccgatggc gcattccgcc aggctgtcgg
    12781 tctccgcgat caccatggcg aaggtcggcc gccggatgtc gccggtgaga cagttgaggt
    12841 agtcctggtg actgcggctg cggtatgcct cagggtcgga cgctttgtgg gagtctacgt
    12901 atagatgtgc cagctccccg gccgggccct gcgccatcca tcggttgacc cgacgcaatc
    12961 gcaccgcgtc cacggcggac gagtcggcat ggggcttgtg cagctgcccc cacatgggct
    13021 gcccgctcac cgcacatcgc ccgagagggc gggtgccggc gcaacagtgc gatgcggcag
    13081 agcggctggg gccgggacat ccccgggagg aggtggcagg ggcctggacg gaacgccaag
    13141 gagcagaaac ctggaaccgg tgaggtcgag gagcagaccc agtgtgggtg gcggatggtg
    13201 cagtcgcagg gtcccacctg tcatggtggt ctgctgtgca gcgtcgagga aggcgttgag
    13261 gccgctgcag tcgcagaagg tgacgggggc gaggtcgaca tcgatggtgc gcatgccgtc
    13321 gtgcagacac cgcctcagtg aggcgcgcac caacggtgcc gattccaggt cgatctcacc
    13381 agcgagggtg atctgcgccc ggtagcttcg gtcttgacgg tatacggtga gctgtgggac
    13441 gggcatgacg cctcagttcg gaagaccatc cggcaacgca cgcggtgacg ccggggtttc
    13501 gggtcccctt ggcgcgctgt cggcaggggc gtacgttcgg cggaggtgga gcaacggccg
    13561 gtccgtcagc ctgtgcgaca ggtaagagga tccacccagt tccctccagg gatgcgccgg
    13621 gtgacggacg aaaggtccgc ttccggcagc catctgtgtc gaacaacgac aagccgccgg
    13681 ggtctgggac gtcctacagc agcatagtcc ccaacccggt gcgaaggacg gcccgaagcc
    13741 gcccagaatg ctgtggacga cgcgaaagcg cactggcgcg cgtatatcgg ttgccgtgca
    13801 cggtacttgg gctgcggcac ggcagcggcg gtctcgtatt tggcagtccg ccgactgcgc
    13861 gagtaggtgg ctccgcgtga cggagccgga cggttcaact ccggtgaagc ccgaccccga
    13921 tgagcccgtg ccggcgtggg cacggatgct gcgctggcgg catggcgaac gggcctcagc
    13981 aaccgccggg gacgctccga cggcgccgga cctcgctgct gctcgatccg gctgtagtag
    14041 tcggccgaca tcccggccgg cgccgccacc tcctcgcgcc gcagcccgcc ggtgcggcgc
    14101 cgctggccgc ggggaagccc gacatcctcc ggctgcaacg cctcacgacg tgggaccgag
    14161 aggaccgcct cgaggaagtt cccggtgccg acctgctggg aatgccaagt ctgactcctg
    14221 cgctgagtcc cgtacatgca gaagaagtag ggcgggtcgc cgctggaagc ggtccggttg
    14281 ccgacgctcc cgtcacaccg ggcgtagttc tccatggtga tgtagtcgct gccgctgaca
    14341 gcgacgggcg tcgcgaaaag gtaagagaca tagtcgtcgc cgtaggccct gcggtgctcc
    14401 tcctgctcgg cggttccgta ggcgacggtc gtgatcggga tgccgagctt cggcgtcaga
    14461 tattcgttga cgtcgagctt cttcagcgcc ttcttcatct cgtcgggata ctcctccagg
    14521 tactgctggt aggtcccgct cagctcgtgg gaccacttcg tgaaggccgc tacgtcgccc
    14581 ttgcccgcct tcttcttcgc gtccttctgt gccttggcgt gccggctcga cttctccacc
    14641 cgatcgagga gcgccaccag cgtgtcctcc cactcctgga tgccctggat gctcgcgccc
    14701 ttagccccgc tgacggactc ggccatctcg ttgcaccgtt ggggcgtcct gacgtccgtg
    14761 ccctgctgct tcctgtccgg caccgagggg atgacctggt ggagggtgac ctcggacttg
    14821 ccggccctgg cgatcttcag gttgcgactg gtggcgacga ggcggacccg ccccttctgc
    14881 ctcgtgttgg ccgcatcgat gtgtgtgtcg gtggcgatga agcacttgaa cggaccggag
    14941 gacggcgtct agcgcacgcc gcctccgacg cccggggcat gtacgtcggc cagtgcggtg
    15001 gccagggacc gccagacgtg ggtggccaga tcgaggttgt gggcgtccgt cgcctgctgc
    15061 ccgaggcggc gcagggccgc gacgccctgg tcgacccggc cctccatgat catcagacgg
    15121 ccctccagga ccgccagccg tacccggtcc ccgtgcggca gccggagttc gccgtccggt
    15181 ggcaacgcgc cgcacagcgt ccgggcctcg tccaaccggc cctggtggaa ggcgagatgg
    15241 gcccgcaggg cgcgtacctc ctgcaactgg atcggggtgc cgatgagttc gaggaccacg
    15301 tcggcctcgc cgagccaccg ctccgccgcc gccacgcacg gcggtgacat ctggagcgcg
    15361 gcggccgtcg ccgccgtacg cagccgggtc cacaggatca ggtcgtcgcc gccccggagc
    15421 agtgccagcg ccgcctccag ccgggaccgg gcggtccggt ggtcgccccg ccgatcggcg
    15481 accaccgatg cggtccacaa cgcctcggcg gccggctggg gagcggccgt gggcagcaac
    15541 tcgctctcca gttcgcgtac atggcgctcg gccgcttcca gtcggccgag gccggtctcg
    15601 acggcgatca ggaccgtctg cgcggccatg acgtcggcgg tcggcagccc ctcggcgcgt
    15661 gcgacggcga gcgcggtgac ggcgaccggt tccgccgccc gtgccttgcc cagggcgacc
    15721 agacagcgcg cgtactgcac gtgggaccgc acccggaggt cgggtgccgc gatcagttcg
    15781 ctcagttcga tcagctcgcg cagatgaccg cgctcccgct cgaagtctcc ctggccgccg
    15841 cggatccggc cgagcagcca cagcgcctgc cagcggccga cggggtcgtc gtgctcgtcg
    15901 tcgcgcaccg cctggaggag ggcggtggcg ctgtccgtgc ccggcggtgc cgaggtcgcg
    15961 gcggcgagcg cgcggctcag gcaaccgccc gcgcgcggct cggtcaacgc ggcgacgtcc
    16021 acgccgagtt gctgtgccag gtagctgacg gtccgtccgg tcggtcggcg ttcgcccgac
    16081 tccagacggg agaggtatcc ggtggacatg ccctcaccga cgaccgcagc ctggctcaag
    16141 ccccgctcga gcctgagctt cctcagctgc cggccgaagt gcggctgctc aagcatttcg
    16201 ccctctgatc ccctgaggtc cttttgagtc ttctgatcgg cccgtgtttc cgaggccacg
    16261 tccggaagtt gcccatactt tagggaggct tggcaatggg ggcaacatgg ttgcgcacgc
    16321 gaggtttctc ctgtcatttg ccatggctcc ctgtgtaccg agtttcggaa cgaccgggcg
    16381 gaggatccag gtggctgaaa ttgccccatg gccaaaagag ttggcaatgg acatgcctgg
    16441 ataggcaaac acttgccagg cgggttgtcc ggccatagcc tccgagttgc cgacctgatg
    16501 tgatatcgcc ccgatccggt ggcgaccgcg cgaaagtgac atgctgacaa cgttgtctcg
    16561 cggggttgcc ggaaagggcg ggctgcatcg aaacccccat gtacagaggg aaagacggta
    16621 tgtccgtggt gaccacaagc atcaccgcct catccaccac cgtcgtcaag gcgggcgccg
    16681 gcgtcaaccg ccgccgcacc tacacggccc atgtatgtcc gaagggcatg acgatcacgg
    16741 ccgcggaagc cgatttcgcg gcacagttcg gggcgagccc cggcgagata tgcgaccgca
    16801 cgctgagcga tctgctccgg gcgggcacgc ccgagttgct gcgtcaccgt ttcaccgacc
    16861 tttccgaggg ccgcacgagc tggttcaccg agcgggtggc cggtcggcac gacagcggcc
    16921 gtgtcttcgc cgccgacctg acggcgatag cggtcaccgg cgcgaccggg ccggccggac
    16981 tggtcctcct gctgagcccc ctgggggcgg cgggcgagcc gtacccccgc gaactgacgc
    17041 tcagcgaact cgacgtgcgg gtcctggagg gcgtggcggg tggtgcgtcg accgtgcagt
    17101 tggccggccg cctgtacctg agccgtcagg gcgtcgagta ccgcgtgcgc ctgttgctgc
    17161 gccgtttcga cgctcccaac cggcccgccc tggtggcccg cgcccacgcg ctcgggctgt
    17221 tcgcgccggg tcagtggccc ccacgggtac tgccggaact catcgagtaa cgggcacgac
    17281 gggggacacg gcgggcggtg gccgtcggcg ggacgatccc gtcggcggcc accgttgcgt
    17341 ccgtcccggg actcggcggg ccgtgcgccc gtcggcgggc gaggtccggt gcgtgcaccg
    17401 tcgggcacct gctcgaagcg ctcggggaat accggccgtt ctcgtgcggc gtgccccggg
    17461 gctccgggcg gaggcggagt gcgggcgtgc cgagcggcgc gcccggacaa ccgccgcccg
    17521 ccgggccttc agggcccttc tccccggtcc cgccgagggg cgcggcgtcg gcaggcgcct
    17581 ccgccgcgtc gcggtcacgc ccgggcactc cgcccggact gcctcctccg cctcgcgtcc
    17641 gcgcgcggcg gatccggctc gggccggccg gaaggcaatg cctccgggcg cggcaggatc
    17701 cacaggacgg ggctcaagcc gccgagggct gccaggcctc ccggaagcgc agtcgggcgc
    17761 ggtgcagccg ggaccgtacg gtgcccaccg gcagtgacag gacacgtgcc atctcctcct
    17821 cgttgaggcc gtaggcgcgc agggtgagga cctgccggtg ggacatggac agccggtcca
    17881 gtacatcgct gatgtgcacg gcgtccagcg ggttcgcctc ctgccccggc tcgacccgct
    17941 ggtacggccc ctcctcaccg gcccgcttca gcgtgcgcac ggcctcgcgg accgtcaccg
    18001 aacgcaccca gccgtagaac gcggtcggct cccgcagcgt gcgcagaccc cggtagacgg
    18061 cgaggagcgc ctcctgggtg gcgtccgcgc cgtcgtcgtg cgtgatggac cggcacagtc
    18121 gtgcgacgta ggggacgatc ccggtcagca gttggttcat ggcctgttcg tcgcccgcct
    18181 gggcgcgcgg cagcagcgcc aggggcgtgg ggatgtcgct gacgttgttc atgtcggcgc
    18241 agggctcctt acggtggccg gtgaggtgcg gtgcggtggg gcgcctcagc ccgccgccgt
    18301 ggggacgggc tcgacggcgg cgcaggcgtc gagcaccgca ccgaccccgt cgcggaaggc
    18361 ccggacgaac tccgggctga aacatgcggt gaagtacggg aactcgatgg ccagccgtcc
    18421 ctcgaacgag acgacacaag ccatcaccgg gctgcgtccg gccgccggga agtactgctc
    18481 ccgggcgggc accagccgga cgtcggtgac ctccagaccc tccggcagcc ggggccccgg
    18541 gacgacgccc atgttcgtgg cgatcaccgt cgccagttgc agcgtggggt tgcgcgggat
    18601 ctcgggcgtg atccgcatct cgtggtaagg gccgtcaccc gcgacgaagt cgccgagccg
    18661 ggagtggacg gtgcgggcca gctcgaccgg gtccgactcc ggtgcgacgt ccagggcctg
    18721 gaggtggctg gtcacggcgg gcaccatcac cagggcgggc agcggcggtg acagccgcga
    18781 gcgcagatcg acgggggaga ggcagcgcag ggcacgcggc tcgccgccgg gcagacgccg
    18841 gcgcgccgtc gtgagcaggg ccgcggcgac cagggcgtgc acggtcacgc ccgccgtgcg
    18901 ggcggtgcgg cgcagccggc cggtgcgctc ctcgtccagc gtcagccggc acacctcgat
    18961 acggccctcg acggcggacg gctccgtgac gtcgtacgcc accaactccg ccgggtgccg
    19021 gcgcgcttcg tccacgcgcc gttccaggta cgcggacgtc gccgcctcgt ccactgcggg
    19081 cagcaactcg ctcacgggca ccgcccagcc ggggacgccg tccgcggcgc cgggccgctc
    19141 ctcgccctcg gccagcgccc ggtagcgttc ccagatctcg ttgtgcaggg cgatgccgct
    19201 gtgtccgtcg acgacggtgt ggtccaccga gagcacgaac aggtggccgt ctccctcggg
    19261 cgcgctcacc aggaccgccc ggctcagggg cccgccgacg gacagcggcg tgttcagctc
    19321 cgtggcgtag gcgtcctcgg cggcgccggt ccgggtgctc agccgggggc gcgcggtctc
    19381 gtccagcagg tccagcgcga agccctcgcc gtccggcacg atacgggtcc gcagcgccgg
    19441 atgcgcctcg gtgaccgcgt cgaacgcggc cgacagcacc tcgatgtcga gacggccgcg
    19501 cagggtgcag gagagcaccg ctcggcttcg ctgcccgacg tacagcgtct ctaccggaca
    19561 caacgcacgg cgcatgaccc aggccctctt ttcgtccgct cattcccgga agccgcgcgc
    19621 cgaccatcgg ccggcgccgc ggatccggct caacgtcctt tcgagagtgc acggtcgggc
    19681 cggtgtgaat ccacccgatg tggagcgccc ggggaaagtc tcgtgttttc cctaaagttc
    19741 gtcgcgggcg cggctatccc ggaacacgcg ttctttaggg aaaaacctga attccgtccg
    19801 cggggccgga tcgggcttga ccgggttcgc ccggaagccc cagcgtgagg acctcgtgaa
    19861 ccggcggcgg gccgcgattc ggccacgtcc ccggagcgcg gccgtaaatg ccggcccggt
    19921 gggccggggc cgcttccctg tcagaccgac cgggctcttt ccggccgggc cgttacggct
    19981 tgccacgtga gggttgtgct atgtcactcc acgaggagtc tctccccgag gacgaacgtc
    20041 gaccgctgtc cggcgcccag gaaggcctct ggtacgcgca gcggctcgcc cccgacagcg
    20101 ccgcgtacaa caccgcggag gcggtggaga tccacggcgg cctggacacc gctctcttcg
    20161 aggcggcgct gcgccgcacg gtcggcgagg caggcacctt cgcgctgcgc ttcctcgaca
    20221 ccgacgacgg cccccgctgc cgtccggcgc cggacgccga cgactggccg ctgcaccggg
    20281 tcgacgtgag cgacgccgcg gacccggagg ccgccgcctg gaaactgatc cgcgcggacc
    20341 tcgcgacccc ggtggacacc gacaagggcc cactgttcgc gcacaccctc ctcaccctcg
    20401 ccgccgaccg ccacatctgg ctgctgcggg cccatcacct cctgctcgac ggctacagct
    20461 acaagctcct cggccgccgc ctggccgacg tccacaacgc gctggccgag ggccgcgacc
    20521 ccggccccgg cggcttcgcg cccgtcggcc ggctacggac cgaggaggcc gcctacctcg
    20581 cctccgaacg ccgtgaccgt gaccgcgacc actggacccg ccgcctggcg gacctgccgg
    20641 aaccggcccg cctcacccgc cgtacggccc cgccgcgtgc cccgttcctg cgccacaccg
    20701 tcgaactcgg cgccccggac gccgaggcgc tgtccgccgc ggccgccggc ctgggcatca
    20761 cccgcgccga cctgctggcc accgctctcg ccgtctacct gcaccgcatg accggcatgg
    20821 acgacctcgt cctcggcatg gccaccatga gccggctcgg cagcgccgca ctgcgcaccc
    20881 cgggcaccgc ctccgacgtg ctgcccctgc gcgtcaccgc ccgaccggac acccccttgg
    20941 cggagttcgc gcgcacggtg gccgacgagc tggccgcact acgacggcac cagcagtacc
    21001 ggggcgagtt catccgccgc gacctcggcc tcctcggcac cgggcgccgc ctgcacggac
    21061 ccgtgctgaa catcgtcccc ttcaccgagg aactggactt cgccggcagc gcggcgacct
    21121 ggcaccacct gtcgggcggc gccgtggacg acctccagat caacgtccgg cccggcaccc
    21181 ggcccggcgc cctctggctg gccctcgacg ccaaccccca cctgtacgag gaggacgaac
    21241 tcgccctgca cggcgaacgg ttcctcgcac tgctgcggcg gcttgcgcag gcggcgccca
    21301 ccaccgcgct cgccgatctg gacctgctgc tccccggcga gcacccccgc gaccggccgg
    21361 tacgcgagtt cccggtcacc gggacgctca ccgagctgtt cgagcggcag gtgcgcgccc
    21421 ggcccggacg gatcgccgtc acccaccagg gcgcacacct cacctacggg caactcaacg
    21481 aagaggccaa ccggttggcc cggctgctcg tcgaacgcgg cgcgggaccg ggccggacgg
    21541 tggccctcgc gctgcaccgg ggcccgcgac tgctgcccgc cctggtggcg gccctcaaga
    21601 ccggagccgc ctacctcccg ctggaccccg cccacccggc cgaacgcctg cgcctggtca
    21661 tggcggacgc ggcgcccgtc ctcctggtca cggagggcgg cctcgccgcg gacctcggcg
    21721 gtgacgtcac cgccgtcgtc ctggacgagc ccgccgtcac cgccgacctc gccacgcgcc
    21781 cggcctccga cctgaccgac gccgaccgcg gcggaccgat cggcccgacg cagatcgcgt
    21841 acgtcatcca cacctccggc tccaccggcc gccccaaggg cgtgcccgtg ccgcattccc
    21901 acgtggtccg gctgttcgcc gcgtcggccg agcacttcga cttcggcgcc gacgacgtgt
    21961 ggaccctctt ccactcctac gccttcgact tctccgtctg ggagatctgg ggcgccctgc
    22021 tgcacggcgg caggctcgtc gtcgtgccgt acgccgtcag ccgttcccca cgggacttcc
    22081 tgcggctgct gcacgacgag ggcgtcaccg tcctcaacca gacaccgtcc gccttcgaac
    22141 agctggtgga cgccgacgag gaacccaccg ccggagcgct gcgctacgtc gtgttcggcg
    22201 gggaggcgct gcgtcccgaa cggctgcgcc cgtggaccgc ccggcacggc ctcgaccggc
    22261 cggccctggt gaacatgtac ggcatcaccg agaccaccgt gcacgtcacc caccaccgcc
    22321 tcaccccgga cgacctgacg gacccccgcc ggggcaacgt cgtcggcacc ccgctcgccg
    22381 acctgcgcgt gtacctcctg gacccgcagg gccggcccgt gccgccgggc gccgtcggcg
    22441 agctgtacgt caccggcgcc ggggtgaccc ccggctatct gcaccgcccc gaactgaccg
    22501 ccgaccgctt cctggacgac ccccacggcc cgcccggcag ccgcatgtac cgctcgggcg
    22561 acctggcgcg gctccgcgcc gacggcaccc tcgaccacct cggccgcgcc gaccggcagg
    22621 tgcagctgcg aggcttccgg gtcgagcccg gcgaaatcga ggccgtcctc gccgagcacc
    22681 ccggcatcgc ccgcgccgcc gtcgtcgtgc gccgtgccga ccatggcggc gaacagctcg
    22741 tcgcctatct cgtgaccacc ggtgaacgac cgcccgccgc ggccgaggtg cgcgaccacg
    22801 cggccgccca cctgcccgag cacatggttc ccgccgcctg tgtgctcatg gacaccctgc
    22861 cgctgaccgc caacggcaag ctggacaccg acgcgctgcc cgcgcccgac ctcaccggcg
    22921 cggcggccgg cacccgcccc gcgagcaccg aacaggcgct ggtgtgcgcc ctgttcgagg
    22981 acgtgctgaa gctgccccgg gaaaccgtcg gcatcgacgc caacttcttc gacctgggcg
    23041 gtgactcgct gctcgccacc cggctgctgg cccggctgcg ccacggttcc ggcaccgacg
    23101 tgccgatcac cgccctgttc gcaggtccgt cgcccgccgc cctcgcccgg ctcctcgacg
    23161 gccgccccgg cacggctccc gaccggcccg ctctcggcga gcggccccgc ccggagcgcg
    23221 tcccgctgtc ctacgcccag gaacgcatgc ggttcctgaa ccggctcgac gactccacgg
    23281 cgacgtacaa catccccctc gtcgtgccgc tcggcgccgc cgccgacacc gaggcgctgc
    23341 gtgccgctct gggcgacctc gccgaccgcc acgagatcct gcgcacggtg ctcgccgacc
    23401 acgacggcac gccgtaccag cggatcctgc cggccggcgg gccgcgcccg ccgctggccg
    23461 ccgtcgactg ccccgtcgac gagatcggcg cgcacctggc cgccgcctcc cgtcaccgct
    23521 tcgacctcac cggcgaacct cccctgcggg cctggctgtt cggcaccggt gaggaccgga
    23581 ccctgctgct cctcctgcac cacagcgcag ccgacggctg gtccctgcgg cccctcgccg
    23641 acgacctgag cagggcctac gcggcacgcc gcgcgggcac cgccccggcg tgggacgcgc
    23701 ccccgccgca gtacgcggac tacgcgctct ggcagcgcgc cctgcttgcc cccgggccgg
    23761 acggtacggg acacgccgag cggctcaccg cgcactggcg ccaggcgctg gccgcggcac
    23821 cgcaggagtg caccctgccc ggcgaccggc cccggccgac ggcaccacgc gacggcgccc
    23881 atgtcaccga gcacgtaccc gccgccctcc accgcgacct caccggcctc gccgagcgcg
    23941 agggcagcag cctgttcatg ctgctgcacg ccgccgtcag cgccctgctc acccgctgcg
    24001 gagccggcga ggacatcgtg ctgggcgtcc ccgtcgccgg gcgctccgaa cccggcctgg
    24061 acgatctgat cggcctggtc accaacaccc tggtgctgcg cgccgacacc tcgggcaacc
    24121 ccgccttccg tgaactgctg gcccgcgtcc ggcccggcga cctggccgcg ctcggccacc
    24181 aggaactgcc cttcgaccgg ctggtcgacg aactgaaccc gccccgccgg cccggccggc
    24241 acccgctgtt ccaggtcatg ctcgccctgc agaacaacga gcccgccgtg ctccgcctcg
    24301 acgggcacgc gacgctgctg cggcccaccg ccaccggcac tgccaagttc gacctcttcg
    24361 tggacgtcct cgaacggcac accgccgagg gcacccccga tggcctggac ctgcacatcg
    24421 agtacgccac cgacctgtac gacccgtcca ccgccgagga gttcgcccgc tcgctgggcc
    24481 ggctgctcgc ggccgtcagc gccgacccgg acgtacggct cggcgggctc ccggcgcccg
    24541 cgccgcgcac accggccgag gcacccggcc ccgacaccgc aggtctgacc gaggcggccc
    24601 ggtccgtgcc cggtatccgc gacgccgtcg cgctgaccgc ggccgacgga ggaccgcccc
    24661 ggctgttcgt ggtaccgggc cgcgcggagg ccaccgaggc cgtcgaacgc ctgctggagc
    24721 gcaccggcac cccgaccgtc ggcgtcaccg ccgtcagcac cctgccccgc gatgccgacg
    24781 gaggcctcga cccggccgcc ctcgccgccc tgcccgccgt cgaccgcgcc gccgccgggg
    24841 cctggcaaca gcgcctcgcc cgcgtcaccg gtgtcggcgc cgccgaggca ggggtcgagg
    24901 acaccccgcg ggagctggcc cgcaggcacg ccgccgcccc gcgccgcgcc gcaccggcgt
    24961 ccgacggcgg cactcgtggg gcggccggga cacggccggc cctcagcgag ggccccgagc
    25021 aggccgaacc caccgtggcc acctgggccc aggccctggt acgggccgcc gaccacgcgc
    25081 ggggcgacat cgtgcacgta caccccgacg gcagcgagac ccgccgtgag tacgcctccc
    25141 tcgtccccga ggcctcccgg gtcctcgccg gactccggcg tgccggactg cgccccggcg
    25201 accaggtgat cctccagtgc gacgccggtg aggacttcct cgcggtgctg tggggctgca
    25261 tcctcggtgg cttcgtcgcc gtaccgctca ccgtgcccgc ctcctacgac accccctcgg
    25321 ccgccctcac caaactggag ggcatctggc ggatgctcgg ccggccctgg atcgtctgct
    25381 cgcccgcgct ggaggcgggc ctgcgcgacc ggatcggccg cgacggcggg tccggtctcc
    25441 ggctgagcac ggccgacgcc ctgcgggacg cgcccgagga ccgcgactgg tacgccgcgc
    25501 agccggacga cctcatcctg atgctgatga cctcgggcag caccggcttg ccgaaggccg
    25561 tccggctgac ccaccgcaac gtgctggccc gttccgccgc caccgaggcc atgaacggac
    25621 tcggcgccga cgacgtgacg ctgaactgga tcccgctcga ccacgtcacc ggcgtcgtca
    25681 tgttccacct gcgggacctc tatctgggct gccggcagat ccacgcgccc acctcctgga
    25741 tcctccagga cccgacgcgc tggatggacc tcgcccaccg gcaccgggtc agcgtgacct
    25801 gggcccccaa cttcgccttc gggctgctcg ccggacaggc cccgcgcttc gcggaccgcg
    25861 actgggacct gaccccgatg cggctggtga tgaacgccgg cgaggtcgtc gtggccgccg
    25921 ccgcccgcgg cttcctgcac gcgctgcggc ccttcgggct gccgcaggac gtgatgcacc
    25981 ccggctgggg catgtccgag acctgctcgg tggtcacgga cgcggtgctg cccgccgaac
    26041 cgcccggcac cgacgagacg ttcgtcagct gcggcctgcc ctaccccggc ttcgccatgc
    26101 gcgtcgtcgg cgaggacacc accgtgctcg ccgagggcga ggccggccgg ctccaggtcc
    26161 ggggcacctc cgtgaccggc ggctaccacg acaacccggc ggccaacgcc gaggcgttca
    26221 ccgacgacgg ctggttcgac accggcgacc tggcgttcct gcgcgacggc gagctgttca
    26281 tcaccggccg cgccaaggac gtcatcatcg tcaacggcgt caaccactac agccacgaga
    26341 tcgagacctg cgtcgaggaa ctgcccgccg tggtccgcag cttcaccgcg gcctgcgcgg
    26401 tccgctccga cgcgtcagcc gccaccgacg aactcgccct gttcttcaac ctcgcccccg
    26461 tccccgaccg cgccgcagcg ctgcgggaga tcgcgggcaa ggtaacccgc gagatcggcg
    26521 tcagccccgc cttcctggtc ccggtcggcc ccggcgacat ccccaagacg gagatcggca
    26581 agatccagcg gaccaagctg cgcaagagct tcgaggcggg agacttcgac gacgccgtcc
    26641 gggaggctca gctgctgctg ggcaccgccg ccaccctgcc cgactggttc ctgaagcccg
    26701 tgtggcagcc ggccgcccct cgcgccccgc gcgtcctgcc gcccggccgg cacaccctgg
    26761 tcctggcctg cgacggcccc tggacccacc gcctcgccga ccgcctggcc cgggccctgc
    26821 gcgccgacgg cgcgcgctgc accgtcgcca cggacggacc gtcctacgaa cgcctcgacg
    26881 ccgcccgcta ccggatccgg cccgccgagg acaccgacca cacggcgctg ctgcgggacc
    26941 tggcggccga cgagcggccg gtcgacgccg tcgtccacct caccgccccg catggcggcg
    27001 acgcggcccc ggacgagtcg gccgcccgca ccctgctggc gctcgcccgg gcgctcggca
    27061 cccggcccgc ggacctgctc cacgtgacgg tggacgccca ggcggtcggc gcgggcgaag
    27121 cgccctcccc ggctcaggcc atggccggcg cggtcctgaa gtcgctgcgg gaggagtcac
    27181 cggggctgcg ctgcgttcat ctggacgtcg aacgggacac ggaccccgta ccgctcgtga
    27241 cggcggaggc cgcgcagcac ctcgtggaca cggaggtggc ccaccgcggc ggacggcggc
    27301 acgtgcgccg gctggccccg ctgcccgagg cgccggaccg cagggagccg cccgccaccg
    27361 acggcttcca cctcgtcagc ggagggctcg gcggagtcgg cggcgcactg gccgcccacc
    27421 tgctggctac ccccggcgcc cgcctgctcc tcctcggccg cagtccgctg cccgaggacg
    27481 gcggaaccca ccagcggcta cgggagctgg gcgacgtgcg ctacgcgtgc gccgacgtca
    27541 ccgacgagga ccaggtgcgg gcggcggtgg acgaggccac cgaggcctgg ggcgtccccc
    27601 tgacatcggt ctggcatctg gccggcgcac tcgtggagcg gcccgtcggc gacctggacc
    27661 cggacgcctg gcgctcggcg ctggacgcca aggcgcacgg cgcctggacc ctgcaccggg
    27721 tcagcgccga ccatccggtg acctcgttcg tgctgttctc ctccgtcaac ggctggttcg
    27781 gcggcgccat gaacaccgcc tacgccgcgg ccaacgccta cctcgacgcg ctcgccctgc
    27841 accgccgggc ccagggcctg cccgcgcaga gcctggcctg gagcatgtgg cacgagcggg
    27901 gtatgagcag cggctacggt ctcaccgcac tcaccgaggc acgcggctac cgggtcctgg
    27961 acgcggccgc cgcactgcgc tccctcgatc tcgcccgcac cctggacgaa ccccatctgc
    28021 tgatcggcgc cgaccgcacc gccccctggg tccgcagcca tgtcgccgaa ccggcccggc
    28081 aggtgcggcg gctggccgcc cgcgtcgcgc tggaggaggg cgccgacctc ggcgccctgc
    28141 accgggcggc cgccgacgcc gcgggcgtcg ccccatgggt gctgcgcgcc gccggcagcg
    28201 ccgaccggcc ggaggccgcc gacgacaccg ggggacggat ccacgtcctg gaacagcggc
    28261 tcgccgagct gtggtgcgga gtgctgcacc gcgaccgggt cggccgggac gagaacttct
    28321 tcgacctggg cggcaactcc ttgctcctgg tcggcgcgca gagcgccgtc aaccaggagt
    28381 tcggctgcga gctgaccgtg gtcgacctgt tcgcgcaccc caccgtgcgc gacctggccc
    28441 gccacctcgt cggccgtacg acggcccccg gaaccccgac cgacgccgcc ggggacccac
    28501 cgagcgggct ggaccgggcg aaggaacagg cacgacggca gcgcgcggcc cggacccgcc
    28561 gctccgcacg gaacggaaag ggccaaggcc atgcatgaga ccgacgggcc gctggacaca
    28621 ccggaggagg acctgccggc cgtcgccgtc atcggcatgg ccggccggtt tcccggcgcc
    28681 gacgacctcg acgcgttctg ggacaacctg gccgcgggcc gcgaagccgt acgtcccgtc
    28741 tccgacgagg agttcctggc cgccggcggc gacccgcgcg acctggacga cccgtcgctg
    28801 atccgcatgg cgtccgtcgt cgagggcata gaccgcttcg actccggatt cttcggctac
    28861 ctccccgccg aggccgccgt ggtcgacccc cagcagcgcc tgctgctgga gaccgcctac
    28921 cacgccctgg agaacgcggg ccgcctcgca cccggcaccg atcacggcac cttcggcgtg
    28981 tacgcgggcg ccggcgacag ccggtactac cccgcccacc tccacccccg ccacgccgga
    29041 cagcccggct ccgtcgagct ggtgcacgcg gccaccgcca actccctggg caccctcgcc
    29101 ccccgcatct cctacgaact gggtctgacc ggccctagtg tgtccctcca gacggcctgc
    29161 tccaccgcgc tcgtcgccgt gcacaccgcc tgccaggacc tgctcgacca ccgctgcgac
    29221 accgccctcg ccgccgccgt ctccctcaac ccctcggcgg cgctcggcta ccggcacgta
    29281 cccgacgggc ccttctcgcc cgacggacac tgccgggcgt tcgccgcgga cgccgccggc
    29341 acctcctccg gggacggcgt cggcgcggtc gtcctcaaac ggctggcgga cgccctggcc
    29401 gacggcgacc gcgtccgggc cgtgatccga ggcagtgccg tcaacaacga cggacggcgc
    29461 aaggtcggct tcagcgcgcc cagttccgcc ggacagaccg aggtcgtgct ggccgcgcag
    29521 gcccaggcga tggtggacgc cgacagcatc ggcctggtcg aggcgcacgg caccgcgacg
    29581 cgcctcggcg accccatcga ggtggccgcg ctcaccgagg cgttccggga gtccacccga
    29641 cggcgcggct actgcgcgct gggctcggtg aagaccaaca tcggccatct gggcgcggcg
    29701 gccggcatcg ccggactcat caaggcggtc ctcgccctgg aacaccggca gatcccgccc
    29761 agcctgcact tcgaccggcc caacccgctc atcgacttcg cggccggacc gttccgcgtt
    29821 cccaccgcgc tggaggactg gcccgccgac ggccgccccc ggcgagccgc ggtcagcgcc
    29881 ttcgggatcg gcggcaccaa cgcccatgtc gtgctggagg aggcccccgc ttccgcgccc
    29941 gcaccgccgc gcgcccccga ggacggcggc cgcctggtgc tgccgttgtc cgcccggacc
    30001 gtcggcgccc tgcgcggcca ggccgaagcc cttgcccacc acctggaacg ccacccggac
    30061 ctgcgcctcg acgatgtggc gcactcgctg cgcaccaccc gcccggccct gcgccaccgc
    30121 ctgaccgtca gcgccgcctc ccgcgaggag gccctgtccg ccctgcgggc cgccgccccc
    30181 gccaccccga ccgtgccgga cgaacccgcc cgggtggcgt tcctgctgcc gggcggcggt
    30241 acccagtacc ccggcatggg cgccgagcta taccgcgacc aggacgtcta ccgcgacacc
    30301 gtggacgagt gcgcccgcat cctgcgcccc gtcctcggca ccgacctgcg cacctccctc
    30361 ttcgagggca caccggccga ccacaccgcc accttcctcg gcctggtcgt caccgagtac
    30421 gccctcgcgc gcaccctgat ggccgccggg gtccgccccg acgcgctcat cggccactcc
    30481 ctgggcgagt acacggcggc ctgcctggcc ggggtcatcg acctcgcgga catgctgccc
    30541 ctggtcaccg aacggatccg gctgatcagc gaggcgggcg gagcgaccgt cagtgtggcg
    30601 gccccggccg aggaggtact gccgctgctc gacgaggagt tgtccctggc cgcggtgaac
    30661 gggcccgccg cctgcaccgt cgccggacac gaggaggccg tggcccgctt cgagcgggaa
    30721 ctcgcccgcc gggacctccc cttccgccgg gtgcggatac cggccgccgc ccactcccac
    30781 gtcctggacc ccgtgctgga gacgtacgag cggcacctgc gcggcgtcac cctgtgcccg
    30841 ccccgcatcc cgttcgtcac cagcgtcacc ggcacctgga tcaccgacgc ccaggcgacc
    30901 tcggtccggc actggctcga ccacacccgc cgcaccgtgc ggttcaccga cgccatcacg
    30961 gccctgtggg agcgcgggcg cccggtcctg gtggagatcg gaccggcgga caccctgacc
    31021 cgactggcca ccacccagct ggacccggac acaccggtca cggtcaccac catgcggcac
    31081 gccaaggccg acgcccgcga cggcttcgtc ctcgccgagg cgctgggccg gctgtggtcc
    31141 gccggtgcgg acaccgcgct cccgccggtg ccgggcacgc cacggccggt gccgctgccc
    31201 ccgtacgcct tcgaacgcca ccgccactgg atcgacgcgc cgggcgcccg ctccaccgcg
    31261 tccgacacct cggacacggt ccgggacgag ccgcacctcg cgccccgacc ccggctcacc
    31321 accgaggccg tgccgccgcg caccgagcgg gaacaggccg tcgcccggct gtgggagcag
    31381 accctcggca tcggcggcat cggcgtccac gacaacttct tcgacctcgg gggcgactcc
    31441 atgagggccg tcctgctggc cggccggctc cgccgggccg gggtgctcga cgtacccgcc
    31501 gccaccctgc tggccgcgcc gaccgtcgcc ggtgtcctcg ccgccaccga ggacaccgac
    31561 gaccagcggt ccggcggcac cgcgaacgcc ctcgcccccc tgctgccgct gcgccgcgag
    31621 ggcggcgccg caccgctgtt ctgcgtccac cccggcgccg gcgtctcctg gcgctacacc
    31681 ggcctgctgc cccacctcgg cggcgaccag ccggtgtacg gcatccaggc cgccggtctc
    31741 gacggcaccc ggccgcccgc acccgacgcc ccggccatgg tcgcctccta cgtcgatctg
    31801 gtccgcgagg tccaaccgca cggcccctac cggctcctgg gatggtcgta cggcggcttc
    31861 gtcgcccacg cgatggcctg cgcgctccag gaacaggggg agcgggtgga actcctggcc
    31921 atgctggacg ccccgcagcc ctactccagc gcatacgacg ccgagacggc cgagcgccag
    31981 gtggcggccc tgctgatgcg ggtggccggc ctgcccgtgc cctcggacgg cgaaccgccc
    32041 gcggtggcga ccgtcctgga ccgcatcgac gccaaggtca cggcggatcc cgccggttct
    32101 ccggtcgacc gcgcgcaggc cgccgccgtc gccgacgtca tgcgcaacaa cctgcgcctc
    32161 gcgccccggt tcgagcccgg tgtcttccac ggggacgtcc tgttcttcag cgccgacgac
    32221 gaaccggcca cggacttcgc cggcgacctc gccgtacagc ccggcaaggc ggacgcctgg
    32281 cgggcccagg tgcggggcac cctgcacgac caccgggtgc cgtgcgggca ctacgagatg
    32341 accgaacccg agcccctcgc cctgatcgga tcggcggtcg ccaaggcact gcgcggcacc
    32401 gccgatccca ccgcgcccgt acccgttccg ccccccgggg gccccgaccg ctcaggagac
    32461 cccgcatgac cgtgaccgca ccccaggacc tctacgaact cggtgacgcg cccgaaccgg
    32521 gcaccgtgcc acggaagatg tacgcctcgc tgatccgccg ggagcgctac gggcagcccg
    32581 tcgacgcgtt ccgcaccgag gtggtcgacg tccccccggt ccgccgtggc caggtgctgg
    32641 tcaaggtgat ggcggccggc gtcaactaca acaacgtctg ggcggcgctg ggcaagccgc
    32701 tcgacgtgat cgccgcccgg cagaaggccg gtggggtcga ggacttccac atcggcggct
    32761 ccgacctgtc gggcatcgtg tgggccgtcg gagaggacgt caagggcgtt cggctcgggg
    32821 acgaggtcgt cgtgctcgcc agccgctggg acgagtcggc cgaggacatc cgcctgggcg
    32881 gtgacccggc cgcgtccgtc agccagcggg tgtggggcta tgaggagaac tacggctcct
    32941 tcgcccagtt cgcggtcgtc gacgactaca tgagccaccc caagcccgcc cgcctgtcct
    33001 gggcggccgc cgcctgctac atggcgaccg cggccaccgc ctaccggcag ttgttcggct
    33061 gggacccgca caccgtccgc cccggcgacc cggtgctgat ctggggcggc gccggtggcc
    33121 tgggcagcat cgccatccag ctcgtccggc acgtcggtgg catcccggtc gccgtcgtct
    33181 ccagcgagga acgcggcgcg ttctgcatgc ggctcggtgc ccagggctgg atcgaccggc
    33241 gcgacttcga ccactggggc cggatgcccg atacctccga cgacgccgcg atgagccgtt
    33301 ggctgtccgg ggcgcgggcc ttcgggcggc gcttctggga cgtgctcggc gagcggcgca
    33361 gcccccggat cgtgctggag cactccggag ccgacaccat ccccacctct ctctacctgt
    33421 gcgacaacgc gggcatggtc gtcatctgcg gcggcaccac cggctacaac ggcgacatcg
    33481 atctgcggtt cctgtggatg cggcagaagc ggctccaggg ctcgcacgcc gcctgcgccc
    33541 gcgaggctcg ggagatcacc cggctgatcg acaggggtgc catcgacccg tgcctgtccc
    33601 ggaccttcgg tttcgacgag atcggcctgg cccaccaact catccacgag aaccgtcacc
    33661 cgatggggaa catggcggtc ctggtcaacg cgtcggagta gagcgtgcgg tggccgggcc
    33721 gtacgacggt cggcccggcc accgcccctc cgaccgaaga cccgcggtcc ggcgcggcac
    33781 ggcgagccgg cccgcgaggg actcgacacc ggccgggccc ggccaccggg ggagcggtgg
    33841 ccgggcccgg tgccggcggt cggggaggcc gcggggaggc gtgtgccctc aggtccgcag
    33901 cagcttcttg acgatcttcc cggcggggtt gcggggcacc tgctcgatga actccactcg
    33961 ccgcggcctc ttgtaggggg cgagcaaccc cgagatgtgg cccagcagtt cccgggcgcc
    34021 ggtgtccggc tcggccacca cgtacgccag cggcacctcg ccgtagtcct cgtccgccat
    34081 cccgacgacc gccgcgtccc gtaccgccgg gtggctcatc agggcgcgct cgatctccga
    34141 ggggtagacg ttctggccgg cccggatgat gacgtccttg gtgcggtcca cgaggtggat
    34201 gcgtcccgcc tcgtccacga accccaggtc cccggtcctg atccacccgt cgaggtcgat
    34261 ctcccgcgtg gcctgcggat cgttccagta gccctgcatc acaccgggtc cgcgcaccac
    34321 gatctcgccg atctcgccgc gcgccgactc cgtcccgtcc gagcccaccg cgcgggcgga
    34381 catacccggg atcacgcgac cgcaggggat gcgcgcggtg gcgttcccgg gcgaggggtg
    34441 ctcgtcgggg ccgagggtga cgaacgggcc gccgacctcc gtcatgccgt acacctgccg
    34501 gaagccgcag cccaggcgcc gcacggcctc ctcgtacaca tcgaggggca tgggggcggc
    34561 gccgtacagg atctcccgga gggtggacag gtcggtgcgg tcggcgccct tggcctggag
    34621 catgaagcgc accatctgcg gaaccatcca catgtgggtc gcccggtgcc gttccaccgc
    34681 ggccagcgcc cgctgcgggg tgaagcccgg catgagcacg atggtggcgc ccgtcgccat
    34741 gtaggtcagg gacaccacca tgctgccgtg gtacaggggg cagcagttga ccatcacgat
    34801 gtcgtcggtg ggccgggcct gcaccagcca gcccagggcg atggcgcgga acgaggcgct
    34861 gtcgaccgtg acgcccttgg cccgcccggt ggtcgccgag gtgtgcagca cggccaccgg
    34921 atcggtgtcg gccacgggcg gcagctcccg ccgcgccgcc accctgccca gtgcctcgaa
    34981 ggccggcttg tcgaacgcca tcgtgatccg caccgaggcg ggcaactccg gctgccggtc
    35041 gagcagttcg gactcgccga acacggcgac cgcgccgacg cgcgccacga tgtcggcgac
    35101 ctcgggcacg gccaggctgt ggttcagcgg gacgaacagc gcgccgaggc gggcgagcgc
    35161 gaagtaggtc tccagtacct cgatccggtc cttggagagc acggcgacac ggtcaccgtg
    35221 ctcgattccg agctccgcga atccccgcgc gagttcgagc gtacggtcgt ggaaaccggc
    35281 ccaggtgacc gcgcgttgct cgtcgaccag tgccgtccgc ccgggaaagc actgccggtt
    35341 gcgttccagc agctgcgtga gccacatcag gcaccgccac cggcaccggc agcggaccgc
    35401 tcggccacga aacgctcgta gtcggcgatt gtctgaagcc tttccatgtc gtctgcggtg
    35461 atctccactc cggcccgctg ctcgaccagc agcaccagcc gcaccaggtc cccggagtcg
    35521 atgccgctcg aggcgaggtc gaggtcgtca ccgacccgcg cggcgtcggc gaactcctcc
    35581 gtgccggtca gctcgaccag caactccctg acggtgctca tggttacccc tttcgcccgg
    35641 caggccgacc gccgagcgga tcgcgtcctt cgcctgtcac ccgaacaaga ggcccccgcg
    35701 ccgaaccgca atccccgcac ccccgcgtga cgtttgtcac gcgccccatc cggcacgccc
    35761 ggggattgcg ggcctcccgg acggcctctt tcccagacgg aggccgcgcc cgatccaccg
    35821 ggcgaggcgg gtgcaacggc gcccgggaag caccgaagga gtgatgccag tgcccaggcg
    35881 aggggtccgg tccaggggtg tgtacgtccc cgccccggcg cggatcggcc ggggaggcgc
    35941 ggcatgagcg cggcagggcc cgccgacacc gcggatgccg gcgaggacga actgacggcg
    36001 aggttcgagg cgctcgtcgg cgccggtgag gccgtcgaac cgcgcgactg gatgcccgac
    36061 ggctaccgcc gcatggtgct ccggcagctc gcgcagcacg cccactccga gatcatcggc
    36121 atgcagccgg agggtgcctg gctcacccgg gcgccctccc tgcaccgcaa gtcggtgctc
    36181 atcgccaagg tccaggacga ggccgggcac ggcctgtacc tgtactccgc cgccgagacg
    36241 ctgggcgtgg accgcgccga cctgctggac gccctgcacc agggccgcca gcgcgcctcg
    36301 gcgaccttcg accaccccgc gctgacctgg gccgacaccg gcaccatcgc ctggctgacg
    36361 gacggcgccg ccgtcatcaa ccaggccccg ctgtgccgta cttcgtacgg accctacgcg
    36421 cgggccatgc ggcgcgtatg ccaggaggag gccttccacg tacggcaggg ctatgacctg
    36481 atgcgcgccc tgtgcgaggg gacaccggca cagaaggcca tggcgcagga cgcggtggac
    36541 cgctggtggc tgccggccgt ggcgctgatg ttcggcccgc ccgacaccga ggcgggcggc
    36601 gccgacgcgc gcaccgcggc ggtcggtgcc gcggtctcgc gccgcgccat ggcctggggc
    36661 atcaagcggc acaccaacga cgaactacgc gcgcggttcg tcgacagctg cgtcccgcag
    36721 gccgaacgcc tcggcctgac cctgcccgac ccggcgatcc gctggaacga ggaacgcggc
    36781 cactacgact tcaccccggt cgactgggac gtctaccggc gcgcgctggg cgaggacacg
    36841 cactgggccc ggcagcgcgt cgcccaccgg cgcgcggcgc acgaggacgg cgcctgggtc
    36901 cgggaggccg ccgccgcgta cgccgcccgc acccgggacg acgacggggc ggccggccag
    36961 ggcgccggtg cgcacgagta cgggcacggg caggagcacg gccacgaccg tacggaggca
    37021 ggggcatgag cggcgggcag ccgttaggcg ccccggaggc gcggccggtt ggcgccccgg
    37081 aggcacggac ggagggcgcc cccgggtcct gggaggtctt cctgcggccc cggcgcggac
    37141 tctcccacca gcacgtgggc tcggtacgcg cctacgaccc ggacaccgcc ctgctcaggg
    37201 cacgcgacct ctacacccgc cggggcgacc ccctgtcgct gtgggtggtc cgctcggacg
    37261 cggtgcacac cgcctccccg gacgaacgcg acccgtactt cgccaacgcg cggcacaagc
    37321 cgtaccggta cccccagcag ttcgcgccgc tgacgaccga gaggagcccc gacggtggcc
    37381 acgacgactg agcgggtggc cgccaccgag gcggacggcc acaccgaccc ccggctcgcc
    37441 gtccagctgc tgcgcctcgg cgacgacgcc ctcgtcctcg gccagcggct gtgccagtgg
    37501 atcacccggg cgcccaccat cgaggaggac ctggcgctgt ccaacatcgc cctcgacctc
    37561 gtcggccagg cccggctgtt gctcaccctc gtcggacgcc tcgacggcac cggacgcgac
    37621 gaggacgacc tcgccttcac ccggaccgac cgcgagttca ccaacgccct gctcaccgag
    37681 ctgcccaacg gcgacttcgc ggccaccgtc gcccggcaac tcgtctacac gcactacgcc
    37741 gtggcgtact acaaggcgct cggcggctgc gcggaccccg aactggccgc gttcggacag
    37801 cgggccgcca aggagatcgc cttccaccgg ctgcacgccg acacctggac cgaacgcctc
    37861 ggcctcggga ccgccgagag cgcccgccgc atgcaggaag gcctcgatca cgtgtggccg
    37921 tacacggcgg aactcttcga cgaggacgac ccggtacgcg agctcgcggc cgccggaact
    37981 gccccctcgc ccgccccgct gcgcccggga tgggagcgga gcacgacgga ggtgatcacc
    38041 cgggccggac tcaccgtgcc gtccccccgc tggcgggccc ggggcggccg tgcgggcctg
    38101 cacaccgagg agttcgcgtc cctggtcgcc gaactccagt cggtgcgccg ccagtttccc
    38161 ggaggcacct ggtgaacggc gccacggccc tcgcggcatc ggagatccgc gcccgggtgg
    38221 aggcgctgcc ggacccggaa ctgcccttca tcgccctcgg cgacctcgga gtgatcggct
    38281 cggtcggccc ggccgccgac ggacgcctcg aggttgagtt cacccccacc tatctgggct
    38341 gcccggcact ggccgccatc gcctcctcga tccgcgaggt cctgacggac ggcggccacc
    38401 ccgacgcccg ggtacggcag gtgctgtccc cggtgtggac gacggaccgc gtcaccgcgg
    38461 ccggccgcgc caagctcgcc gcccacggca tcgccccgcc cgcgcccgca tcgggggacg
    38521 gcccggtcct cgtccggctg accggggttc cttgcccgca ctgcggttcc cgggccaccc
    38581 ggccgcacag cgcgttcggc cccacccgct gccagtcgat gctgcgctgc accgcctgcc
    38641 gcgagctgtt cccccacctg agcgcgctat gaggacgcgc ccgaaccccg tcctcgcgcc
    38701 cgacggcacc cgtcggcgca ccggctggca ccggctcccg gtcaccgccg tccagcacct
    38761 caccggcgac gccgtcgccg tcaccctgga cgtaccggac accctccgcg ccaccttcgc
    38821 gcaccggccc ggcgagcacg tcgtcgtccg gcaccgccgc tcgggcgagg aactgcgccg
    38881 cagctactcg gtgtgcccgc cgcccgagga gcccggcgcg ctgcggctgg tgatcaagcg
    38941 gggcgccccg gacggcttcg gcgcgtacgc gctgacccgg cttgcacccg gcgaccgcct
    39001 cgaactctcc gcgcccgccg gggccttcgc cctgcccgag ctgcccggag cccaccacgt
    39061 gctgatcgcg ggcggctccg gcatcacccc gctcgcggcc atgggcgcga gcgcgctgcg
    39121 cacggacccc acctgccggg tccacctcgt ccactcggtg cccacggccg cggacgccct
    39181 gctcgcagac gaactcgccc tgctcaagga cgcgttcgtc gaccggttca ccgtgctcca
    39241 tctgctgacc cgcgaaggac gcccgcccct ggacggccgg atcgacgcgg agcgcctgcc
    39301 ccggctgctc gccgcgctgg acgtccggcc gggcccggac accaccttcg cgctgtgcgg
    39361 cccggccggt ctgatcgcca ccgtccgacg ggcgctgaag gacgcgggag ccgacccggc
    39421 cctggtccgc tccgaactgt tcgccctcgg cgacaccccg ccgctcccgc ccgtaccgag
    39481 caccccgccc gtacccggtg ccgtacccgg cgcgccgcgc acccttgagg gcacccgggt
    39541 caccgccctc tacgacggcc accgcagggt cgtcaccgcc gggccgcggg accccgcgct
    39601 cctcgacgcg ctgctgcgcg accacccgga cgtgccgtac gcctgccgcg agggcatctg
    39661 cggcagctgc cgtgccaagg tcctcaccgg cgaggtcgcg accggccccc agtacgccct
    39721 cgacgccggg caactggccg ccggctacac gctcacctgc cgcgccaggc ccctcggcgg
    39781 cgaggtcacc gtcgacttcg acgcatgaca tgacggcacc cgccccggcc accacccacc
    39841 ccagcagaag gagaaatcga tgaccacccc cttgcggcac gagggcagga ccgcgctggt
    39901 caccggcggc agccgcggca tcggccgggc cgtcgcccgc cggctggccg gcgagggcgc
    39961 cctcgtggcc gtccactacg gacacgacca cgaggccgcc gagcgcaccg tcaaggagat
    40021 cgagaccgac ggcggacgcg ccttcccggt ccacgccgaa ctgggcgtgc ccggtgacgc
    40081 cgacaccctg tggacggcct tcgaccacgc cctcgccggg caggacgccg ccccaggcct
    40141 ggacatcctc gtcaacaacg ccggcatcac cgtcccgcgc cggatcgcgg acgtcaccga
    40201 ggacgactac gaccgggcgt tcgcgatcaa caccagagcg ccgttcttca tcatccagcg
    40261 cgctctggac cggttgcgcg acggcggccg gatcgtgaac gtctcctcgg tcgccacgcg
    40321 cgtcgccttc ccgccgatca tcgcctacac catgaccaag gccgccctcg actacctcac
    40381 cctggccctc gcccaggaac tgggaccgcg gggcatcacg gtgaacagcg tcgcgcccgg
    40441 ctacaccgag acggagatca acccgacgct cgccgtcccg gagatccgcc gacggtacga
    40501 ggctgcttcc gtgttcggcc ggctcggggc cccggcggac atcgccgacg tcgtctcctt
    40561 cgtggcgagc gacgacgccc gctgggtgac cggccagtgg atcgacgtct ccggcggagt
    40621 ccacctcggc ccgtgagccc cgcgcccgta ccgccgcgcc gcccgcggca gcaacaggag
    40681 gccctcacca tgaacgacgg cacgtccgca ccggcccggg ccgcggacga ctcactcacc
    40741 cggcccttcg acggtgccag cccctacgac gcctatgtgc acgcgtccgt cctgaacaac
    40801 ctccagcagc ccctcaccga ggcgcccgac gagatgggtt tcgtcgtcac cacccaggtg
    40861 atggagctgt ggttcaccct gatcgtccac gagtggcgca gcgccggcac ggccttcgcc
    40921 aaggacgacc tggacgccgc catggacgcc ctggcccgca gccgccgcgc cctgaccgcc
    40981 ctcaacgccg cctgggcgcc cctggccgcg ctgacccccg cccgcttcaa cggcttccgg
    41041 gccgcgttcg gcaaggcctc gggtttccag tccgcgatgt accggcaact ggagttcctg
    41101 ctcggcgaca agtccgaggc gatgctccgc ctgcaccggg gcgaccccga cgtgcacgag
    41161 gcgctgagcg agacccaccg ccagccgtcc ctgtacgacg aggtgctggg ctgtctgcac
    41221 cggcgggggc tgccggttcc ggagcacgtc cgggagcgcg acgtgagcgc gccctacacg
    41281 tcggacccgg gcgtcgtgga ggtgtggcgg ctgatctact ccggccccca gcaccatccg
    41341 ctgctcggcc tcggcgaact gctcaccgac atagcggaac tcgtcctgcg ctggcgcttc
    41401 gaccacgtca tggtcgtccg ccgggccatg ggcaccaaga gcggaagcgc gggctcgacc
    41461 ggcctcgcct ggctcgaaca gcgcgcgaac aggccggtct tcccggagct gtgggaggtg
    41521 cgcggtgggg tctagggtga tctccgcctt cgcggcggag gaggagcagc gggtactgag
    41581 cctgaaaccg gtgctggcac cggcgcacgg ccgctacggc gaccacccgc accaggccta
    41641 cgacgcctgg ccggccgaag accccggcgc ccctctggtg atcctgctgc acggcggcta
    41701 ctggcgctac gaccggatgc acctcactcc tttcgccgcc tacctcgccg agcagggctt
    41761 cgacgtgctg ctgccgggct tccgccgctc cggcggggcc ggcggtcatc ccgagacgtt
    41821 cgacgacgtg gcccggatcg tggacaccct tcccgccggg cggccctacc tcctggccgg
    41881 tcactgttcc ggcgggcatc tggccctgtg gtgcgcggcg cgcggcctgc tgcccgccgg
    41941 ctcccgctgg cacaccggca ccctcccgac cggcgtcctc gcactcgccc cgatcacgga
    42001 cctcaccgcc acccgccggg acggcctcag caacgacgcg gccctgcaac tcctcggggg
    42061 agaggccgtg ttcgaggaac ggctgcccgc cgtcgacccc ctcaccctgc tgcgcggggc
    42121 cggtaccacc ggtgtgccga cggtgctgct gcacggcgcc gtggacgagg aggtcccgct
    42181 cacccagttc accgactacg cggccgtgca cgaagacctg aggacggtcg tgctgcccgg
    42241 caccggccac tacaccctca tcgagcccgg agcccccgga gcccgcgcgg tcgccgacac
    42301 cctgtgggag atgtccgccg gcttcgccgc accgcgcgac ggcaccgacg cggcccccgc
    42361 acaccgcacc gataccggca ccgccccagg gagggccacg cacccatgac cgccgccacc
    42421 ccgctcgaag accgggccgc cctcgccgac gccgaggacg ccttggcccc gctcgccgag
    42481 cggttcgtcc tccctgaggg cgtcatctac ctcgacggca actccctggg cccgctgccc
    42541 gccgccgtcc cgcccgccct cgcggacgtc gtggcccgcc agtggggcac cggcctgatc
    42601 ggctcctgga acgacagcgg ctggtgggac gcgcccctgc ggatcggcga caccatcggc
    42661 cgcctcgtcg gcgccgcgcc ggggcagacg gtggcgggcg actccaccag cgtgcagttg
    42721 ttcaccgcgc tcagcgcggc caccgcactg cgccccgacc ggcccctgct ggtcacggat
    42781 cccggccact tccccaccga ccgctacctc gccgacgcgg tggcccgccg cggcgacgcc
    42841 ctggaggtgt gccggatacc cccggccgac ctggagaagt tcctcgccga acagggcccc
    42901 cgggtggcgg cggtcagcta ctcaccggtc gatttccgca ccggcgagct gtgcgacatg
    42961 gcggcgctga ccgaggccac gcaccgggcc ggcgcgctcg cggtgtggga cctgtgccac
    43021 gccgccgggg cgatgccgct gcacctcgac gccctggagg tggacctcgc cgtcggctgc
    43081 ggctacaagt tcctcaacgg cggccccggc gcgcccgcct ggctctacgc cgcccgccgt
    43141 caccacgatg ccctcgacac cccgctgacc ggctggaacg gccatgcgag ccccttcgcc
    43201 atggaccggg actacacccc cgccccgggc atcgcccgcg cccgtatcgg caccccgccc
    43261 atcctgtccc tgctcgccct ggaggcggcc ctcaccgtct tcgaggacgt ggacctcgca
    43321 caactgcggg ccaagagtgt gtcgttgacg gagttcttcc tggcctgcgc cgaggaactg
    43381 ctcaccccgc tggacatcac tccggtgaca ccccgggacg cggcccgccg gggcagccat
    43441 gtgtccctgc gccacccgca cgccctcggc ctgacccgag ccctggcgga ccggggcgtc
    43501 gtcatcgaca tgcgcgcccc cgacctgctc cgcttcggcg tcaacgcgct ctacaccacc
    43561 cacaccgaac tgttcaccgc cgcacagcgc ttgagcgcca tcgtgcgcga gtcgtcctac
    43621 gaccccgcgc cctcacggtc gggcccggtc acctgagcct gaactccgcg tcgaaccccc
    43681 gccccttgcg ggcgtgctgg tctttcagct ggctgcgagg acggccgtcg acgcctcggt
    43741 ccggtagtgg ggtcgtacca ggcggcggga catgagcgtg atgaacgccc gctgaatgtg
    43801 gacttcggcg tgggacatca ggggctgccc gcgccagtgc cggggtgaag atgggctcgc
    43861 ggtcgtcgaa gtggtcgcgc ctgccccgac ggccgttcgt gagcccggcc ggcgcggcac
    43921 cggcgggtcg gcgctcggcg gaagccacgg ctgcaccggc gccccggcgg aagtcgccgc
    43981 ggactgcccg cccgtagtgg gcccctgctt ccgggcgtgt cgggtcggcg ggatattgtc
    44041 ccgctgcttg ttcacttttt ctcacaggag cctcatgcgc ctcagacagg tctccctggt
    44101 cgcgaccctc tcgctcgtgg ccggcctgac caccgccacc gtcggactgg ccggctccgc
    44161 ggtgtacgcc gacgacacgg ccgcgctgcc gctgtccggt tacgcgcacc tggtggtcga
    44221 ccccgcccac cagcacgtct tcgtcagcca gggagccggc tcgaccggca tagtggtgac
    44281 cgatctttcc ggcaccccga tcaccaccgt tgcgggggag cagggcgcca tcggtctggc
    44341 gctgtcgcct gacggcggca cgctgtacgc ggcgctggcg gacggcggag cgatcgccgc
    44401 gatcgacaca gcgacgctca gcgagaccgc ccgctggtcc accggcgcgg gcagctcccc
    44461 cgtctccgtc gcggtggcgg gcggccgcgt ctggtacggc tacacggccg acggcaaggg
    44521 cggtatcggc tcggtcgacc cgtccgcgcc cgcgccgtca gcggtcccgc agcctggcct
    44581 gtcgcagtgg acgaccgcac cgctgctcgc cacgggcggc gatgtgctcg tggccgagga
    44641 accgcagggc aacctcagtc atgtggcgac cttcggcgta gcttcgggca cggcgtcggt
    44701 caaggcggac accctggtcc acggaggcac ggcaaccggg ctcgccgtca ccggcgacgg
    44761 cacgggggtg ctgctggccg ccccgcagca gctcgccctg cgggcgtacc gcagcacgga
    44821 cctcgcggcc gcagaccccg ccgcgtactt caccggcggc tccggttccg cgcctggctc
    44881 ggtggccgtc gacaccgacg gcacggttgc cgtcgccggc acctccggcg tttacctcta
    44941 cgccggcccg aacacccttg ccgagaacca cctcaccttg ccgtccggca cggtcgctcc
    45001 ggacggcctg gagtggggcg ccgacggcac gaccctctac gccgtcacca aggactccgc
    45061 gggtgcctac agcctgaacg tgctgggcgc cccgaagctg acggacagtg aactcgccct
    45121 gcggcacccg cagtacgcgg tgccgaccga gcggtacacg gtcagtggct tgctgagcac
    45181 ccgcggtctc ctgccggcag gcgccgcgct gaaggtcacc cgcgacggca ccgccctgcc
    45241 cgacaccaca ctcggcgcgg acggcacgtt cacgttcacc gacctccagc aggacgaggg
    45301 cacatacacc taccaggtgg cgtacgccgg cgacgccacc caccgctcca cggcggcctc
    45361 actggccgtg aacgtggcga agctgccgac cgatgtcgtg ggcaccgaca tcacctcggc
    45421 gaaccccggc tcggtcgtcc tcaccggccg cctcatggcc cagctgggcc tgggcacctt
    45481 tccgcagggc accaccgtcc aggtggcccg gcgcgacgag agcacccagc agaccgtgcc
    45541 gctgggatcc gtacccgtgg acccgaccac cctccggttc accgtcaccg acgccccggg
    45601 cggcgccggc tcgttcatgt acgtcttcac gtacgccggg gacgccaccc accagccgtc
    45661 cgagagcggc atgagcctcg tggtcgcccc gtacgccccg gcgctgacgc tgagcgcccc
    45721 ggcgaccgct gtccgagggg cggccctgtc cttcggcggc aagctcggtg acggcccgta
    45781 cgccgccggc cggacggtca ccgtctcccg caaggacgcc gcccgcagca ccccggtgac
    45841 ctggaccacg ccggtggccg ccgacggcac cgtcacggtg aacaacaccc ccgacatcgg
    45901 cggcgccaac acctacacgg tcacctaccc gggtgacgcc tcccacaagg cggccaccgc
    45961 ggtcgccacc gtccaggtgt cccgcgcggc gaccgccctg accgtcacca gcagcgcgcc
    46021 ctcatacgcg tacggcgcga cggccaccgt caccgcccac ctgggcacca cctacaacgg
    46081 ccgcacggtg tccatccacg ccatgcccta cggcggggcg aagaccctgg taacgacggg
    46141 caccgtggac gcttacggca acctgaagac cacctacaag gtcacccgca acaccacctt
    46201 caccgcgtcc ttcgcgggcg actaccgcta tgcccccgcg acggccaccc gcgccgtcaa
    46261 cggctacgtg aagatcgcga cggcgctcgg cggctactac acgagcacca cgtacagcgg
    46321 gatcacctac cgcgtcttcc acaagacggt gaagcccacg gtgaccgcga ccgtcacgcc
    46381 caacaaagcc ggccagtgcg agcgcttcga ggtccagcgg tactacagcg ccgcctggca
    46441 cacgctcacc acgtcgggct gctacgccct gtcgtcggcg agcagcgcga aggcgcagct
    46501 cagcctcacc aacgcgctca accagaagtt ccgcgtccgc cccaagtacg agcgctccac
    46561 gaaggacctc agcaacgtga gcacgtgggg cggttggctc tacttcgtgg tgcgcacctg
    46621 acacccgtga cccggccgga ggccgcccgg acgacgcccg gccgtgcccg ccgtgtgcag
    46681 cctggcgtac gccgccctgg tcctgctgga ccagggcagg cacgggcccg gtccaggcgc
    46741 cggtggtgat ggtgcctgcc cgctggtgac aggagcggca ccgcgaccgg cccgccggtg
    46801 cggcggccgg cccggccggg tcgctgttgg cgtgcgtgct gctcggccag ctgcgcacac
    46861 gtgcatgagg acgagaaaca ggtcgtccag gacgaagtcg gaccggccaa caaagggatc
    46921 cacgccacat cgaccgccac ccaggtcatg gcctcccgac gcttcgcagg gttggtgatc
    46981 caggcgttcg gagcctgccc tcagcacgcg ccactaccac cgccggcacg actggcctcc
    47041 gcatcaccgc acggctcgcc gcggtaaatg ccggatttgc tgcggcagta ccggaagggt
    47101 gggacggacg gtccgccgca ggtcgcgacg atcacggcga gggctccctc gcagcaaatc
    47161 cgttattcac tacggcagtt gtcaatacgt ctccgtgatc gcacaactgc ccgagtgtgg
    47221 gtctgctgtg cagtgcgcga cgccgacgag gcctagcgcc aacatgtttg cctgggtcat
    47281 gcccgcagat cttccgtcaa gggcaggcac tcggcgagca ggtctacgac gtcgcgccag
    47341 gctcgctgcg cgtgctgtgg gtggtagccg acgccgggga ccgtggggtg gtggaccggc
    47401 gggtggtgga aggcgtgcaa ggcgccgccg tagaccgcga ggcgccagtc gacgcccgca
    47461 gcctgcatct cggcggtgaa cgcgttccgt tgcgcgggcg gcatgatcgg gtcttccgat
    47521 ccgacgccgg cccacaccgg gcagcgaatg cgcgctgcct cgcccggtcg gcccgtggtc
    47581 agtgcgttga ctgtcccgat cgcgcgcaga ctgacgccgt cgcgcccgag ttccagtccg
    47641 acggcgcccc cggtgccgta gccgacggcg gcgatccggt cgggatcggt ccgcggttcg
    47701 gtgcgcaaca cgtcgagcgc cgcatggccg atgccccgca tccggtcggg atcagcgagc
    47761 agtggcatgc aacgggccag catctcctcg gggtcaccca aatagcgccc gccgtgaagg
    47821 tcgaaggcca gcgctacata tcccagctcg gcgagagcat cggcccggcg gcgctcgacg
    47881 ttgctgagcc ccataccctc tggtccgagc agcaccgcag gccggcggtc gacaccggcc
    47941 gggagtgcga ggtgcccgat catcgtcaaa ccgtcggccg ggtactcaac cgtacgcgtc
    48001 gtgatcgtcg tcatgagact ggactgtagt gatcgtcgag cccggtccgg ccggtgttct
    48061 gccgctggca gaacagcgcg ggtgcccctc tgagataggg cgagggcccc ggcggtcagg
    48121 gcttcaagat catcgagggt cggccttcgg ggcgatccgg tacgcggtgc cgggcgggcc
    48181 aaccggtcag gcgagggcgg ccgttccgcg aagccgcgga ccacggcggc gagttgggtc
    48241 atcgcggggc agactgcggt gacccggtcc agcagatcac ggtgctcggc ctcgaggttg
    48301 tcgggcctgg tgaggggcat ccgggcgggg aggcgcgggg gagttgtggc tgcggtcagc
    48361 gtccgcgcgg cccaaggtga cctacgtgtg caggcggttg aggcatccgg tgaacccttg
    48421 gcctctgatc tcaccgaaga ggtgcttgac cgggacggtg gggtcttcgg ttcctcgccc
    48481 acgatgaccg tcgtcacgac gacccgcccg aagcccggct gtcacctggt ggccgtgaac
    48541 cggccgaagc cttcgcggcc gcgcggcctg tgtcgacgcc ccgacgggat cggtacgtca
    48601 ctgaggtcgc gctccccgcg acgggcacgg gcaaggggcc ccggcacggg gtgtgcaccg
    48661 gcggacacca gccgcatcgc cccgaaggcc aggccgcggc tgctgtccgt cgaggccgag
    48721 ggctgcaccg aggacgcccc ggtcggcgca gccgagttcg acaagcacac gcgtcatgtc
    48781 cgccgtgagg tgaaggacac cgacggccgg ccccgtcgct cgatcagctc ctcagggcgt
    48841 ccacggcccg agcatgttct tcatcgcatc cgtcatcgcg aactgcagca gcgggccgta
    48901 ggtgatccgg ccgacgccca ggcggcggaa gcgttcgaga tcgtgcttga cgggatgggc
    48961 cgtggagttc accggaacgg cgacggcgcc aatcaccgcc gcgagcaggc cgtcgtcgtc
    49021 ctgaataccc accgggtaga cgctgtcggc gccggcctgc tccagggctc gcagtcgctc
    49081 gattgcctcg tcgaggacac cggaagcgtc cttcgcgtgc aggaagaggt cggtgcgccc
    49141 gttcacccag accggaactc cggcgtcgtc agccgccccg cgcaggccgg cgatgtagct
    49201 cgcgtgctcc tgtgtgctgc gcacacggcc gccgtccgag tggacggtgt cctcgatgtt
    49261 gagaccggcg ccgccgactt cgatgagccc ggcgacgaga tccgcgggct tctgtccgta
    49321 tccggcctcc aggtccacgg acacggggat gtcgaccgcc gcgatgatcg gcctgacggc
    49381 ggtgagtact tcctcgaagg tctgcccctc gtggtcgtcg gctccccggg agtcggcgag
    49441 cggatggctg ccgaccgtca gcgcggggaa cccggcggcg gctgccgtcc gggcggacca
    49501 gacgtcccag acggtcggca gcacgagcgg cttgtactcg gcgtgcagct gcttgaggcg
    49561 ttgagcgcgc tcaacagtgg tgcgagagtc catgccgagg acgctacacc tggattgcca
    49621 cgaatatcgt gccggagggg cgccgcccgg tgacggaaag acgcagcctg gttccattct
    49681 gggttgccga cgtgggcagt gggcggggcg atctgaggga tgccacatct ggctccgaac
    49741 atcatcggat gcatggcgtt agccgttgat cctgtgactg agggcggtct caccagtggc
    49801 ttcgcccagc tgccgtgcca tcccctcgaa ctgcaccggg tggatccgcg tgcccgacct
    49861 gacgtggtcc cgcatcgatc acccctcaga cgcggtcgag ggcgaccagc ggatcaccgg
    49921 tgaggtgatc acgcctcaga cgcgtaatgg ccaggtcgtg atctccctga aagctctccc
    49981 ggaagacccc ctcgtgcggt tcgccgatct atcaggtcat gtcgtcaacg ggactgtcac
    50041 gaagatcgtc ccgttcggcg tgctcgtgtg gctcgcccct ggcctcgagg ggcttctaca
    50101 cgtctctgag acgaccgacc cgccagtcgg aagcccagac cagctcgtga gcgaggggga
    50161 cgggatcacg gtgcgggttg cggaagccga tcttcagaga caccgcgtca ggctctgcat
    50221 ccatgactct tgagtccggg tcgccggggc agggcaggat ggcacatggc ctgaccgctc
    50281 cgaggagagt ggtcgatggt ggacatggcg tgttccccgg cgctttgagg tcgaggccgc
    50341 agagcaacgg gtggtcaatg gtggccgggc catatcagcg gcgcccccac ttacaagatc
    50401 acgatctacg gctggagtat tagcggaagc tgaaaggatc cagtacctgc atcacctgga
    50461 cgacggctgg tctgccaccc accggtctga ccatggacga tgacgcgatc agatcgccga
    50521 actccacgag ttcaacccga gtgacttctt tgtggcgact gcgaacccgg taccgcccga
    50581 ggaccggacg cagggttctg cctcgtcggt gtgccttgga ggtacggtca aggtccggac
    50641 cggcgccgac gccgaccccg gcccggacct tctccggtgt cgggcggtac accgtggagg
    50701 ggttcaggcc gcatgtgtgc tgccgacccg cccgtggctt tttttccgca ggtaacgccg
    50761 gttgcgccgt gatgagtagc ggaagccccc cgggtcgcct ctgacgcact tcggctgcgg
    50821 tctcgcagcg cactgcggtg acgaacttgc agaaaccgcg cggcccagga aggggttctg
    50881 tcgcgtgaca gttccgcgtc ggctccggca ctccaaccgt ccctccgcct tggagcgagg
    50941 tggtccagga ccttgacgct ggtgtcggac gacggtcagg tcgcggtcga cagaggcgct
    51001 ccgggctccg gtcgagtggc ggcggtggga gtcgtgcgca ccgtcagggt tgggcagcat
    51061 ccgccagggg gagcctgtgt cctgcggacc gctgactgac gcggaacccc tgtggtgtag
    51121 cggccgttgt tcgaaagccg gaaaaacttc agggatggag ttgatgcacg gtggaacgac
    51181 gcatgccggt ggcgacgcac tggggcagtt tcgtagccgt ggtcgattcg ggtcagctgg
    51241 tgcgcattga gccccggggt gatgaccccg cgccgtcgcc gatcggcccg ggcatggtga
    51301 cggctgctga ggacagtgcg cgtgtgctgc gtcccgcggt gcgccagggg tggctcaacg
    51361 gcttgccgcg cgccgatgaa acggccagag gtgcggacgc cttcgtagag gtcagctggg
    51421 acgacgcgct cacgctggtg agcgaggaac tgcgccgagt gcgcgcacag cacggggaca
    51481 gcgcggtgtt cggaggctcg tacggctggg ccagtgcggg cgggttccac aatgcgcagg
    51541 gtcagctcca gcggttcctg gcgttgggcg ggggctacac cgactcgcgc aacacgtaca
    51601 gcaccgccgc tcttgaggtc atccttccgc atgtgatcgg cggggctccg tggagctacc
    51661 agtcccggat gccgatgtgg gacgagatcg ccgagagctg tgagctcgtg gtggcgttcg
    51721 gggggctggc tctgaagaac agtcagatca accctggcgg gctggcccgg caccagacgc
    51781 gggacctgca gcggaagtgc cgtgaggccg gcgtgcggtt cgtgaacgtc agcccgatcc
    51841 gcagtgacac cgccgacttc ctcgacgccg agtggctgcc ggtcatcccc aacaccgaca
    51901 ccgccttgat gctcggcatc gcgcacacga tgctggtcaa cgactggtac gacgaggact
    51961 tcctcatccg ctgctgcgag gggttcgacc gcttcgcctc ctacctaacc ggcgacgtgg
    52021 acggcgtcgt caaggacgcc gactgggccg cgaggatcac gggcgtcagc cgcgacacga
    52081 tccccgatct cgcccgccgc ctgtccacac agcgttccct catcatggtc aactacgccg
    52141 tacagcgggc ggaccacggt gagcagccga tctggatgtc ggtcgtgctg gcggccatgg
    52201 cgggttcgct gggccggccc ggctgcggct ggggcgcggg ctacgcgacg atggacgcga
    52261 ccggtgttgc cccgggccga ccgtctgtgg cgtcgatgcc gcgggcggcg aaccctgtcg
    52321 cggacttcat tccggtcgcc cggatcgccg acaccctgct ggaaccgggt gcgaccatcg
    52381 actacgacgg tcagcgcctg accctgccgg acctgcgcct gatctactgg tgcggaggga
    52441 accccttcca ccaccaccag gacctccac
//
