LOCUS       NZ_LMEQ01000030        20591 bp    DNA     linear   CON 07-JUN-2024
DEFINITION  Streptomyces sp. Root1310 contig_4, whole genome shotgun sequence.
ACCESSION   NZ_LMEQ01000030
VERSION     NZ_LMEQ01000030.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root1310
  ORGANISM  Streptomyces sp. Root1310
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 787452)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 787452)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140604
            Assembly Name                     :: Root1310
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001426425.1-RS_2024_06_07
            Annotation Date                   :: 06/07/2024 02:14:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,470
            CDSs (total)                      :: 8,385
            Genes (coding)                    :: 8,123
            CDSs (with protein)               :: 8,123
            Genes (RNA)                       :: 85
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 262
            CDSs (without protein)            :: 262
            Pseudo Genes (ambiguous residues) :: 0 of 262
            Pseudo Genes (frameshifted)       :: 98 of 262
            Pseudo Genes (incomplete)         :: 219 of 262
            Pseudo Genes (internal stop)      :: 20 of 262
            Pseudo Genes (multiple problems)  :: 64 of 262
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:32:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 440415
            Orig. end                         :: 461006
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMEQ01000030.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20591
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="linaridin"
                     /region_number="3"
                     /rules="(cypemycin or cypI)"
                     /tool="antismash"
     cand_cluster    1..20591
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cypemycin or cypI)"
                     /kind="single"
                     /product="linaridin"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20591
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:10591](-)"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10591)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cypemycin or cypI)"
                     /neighbourhood="10000"
                     /product="linaridin"
                     /protocluster_number="1"
     misc_feature    complement(10..26)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.48"
                     /tool="antismash"
     misc_feature    complement(37..51)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: weak, score: 24.7"
                     /tool="antismash"
     misc_feature    160..174
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 22.14"
                     /tool="antismash"
     misc_feature    complement(523..538)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.66"
                     /tool="antismash"
     gene            complement(599..1078)
                     /locus_tag="ASD48_RS29170"
                     /old_locus_tag="ASD48_19575"
     CDS             complement(599..1078)
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015613067.1"
                     /locus_tag="ASD48_RS29170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19575"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_057604728.1"
                     /transl_table=11
                     /translation="MNLDIPEGRNPIEYVWGDMVPGIGLAAANFSLSVYAHTTLGLREF
                     EAARLRIAQINGCLFCLDWRTERDEQKVEEEFADAVAEWRTTDAFDERTRLAAEYAERY
                     ALDHHGLDDEFWDRMTAHYSQTEIVELTMSLGSWLAFGRLNRVLGLDAMCVLPGH"
     gene            complement(1170..2243)
                     /locus_tag="ASD48_RS29175"
                     /old_locus_tag="ASD48_19580"
     CDS             complement(1170..2243)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127349.1"
                     /locus_tag="ASD48_RS29175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19580"
                     /product="dihydrodipicolinate reductase"
                     /protein_id="WP_057604729.1"
                     /transl_table=11
                     /translation="MISTVVWGTGNVGRAAIRAVEAHPALDLAAVLVHNPEKVGRDAGE
                     LGGLGRGLGISATDDIAAVLSEGPGAVVYAASGDIRPDEALADIGAAIRAGAVVVTPAL
                     YPLYDQRNAPPEFRDPVLAAIADGGGSLFVSGVDPGWGNDVLPLLMSGLGTVVDAVRCQ
                     EIFDYSTYEQEESVRYLVGMGQPMDYEPLMLAPSIPTMVWGGQIRLMARALGVELDEIR
                     ETLQRRALDATVSTRTMGEFEAGTQGAVRFEVQGFVKGEPRLVIEHITRIHPSCAPDWP
                     SPPNGDGAHRVIIEGRPRIEVTVEATDEGENRSAGGNATAVGRLVGAIDWLVDAEPGLY
                     DALDVPLRPAVGRLGGK"
     gene            complement(2474..3961)
                     /locus_tag="ASD48_RS29180"
                     /old_locus_tag="ASD48_19585"
     CDS             complement(2474..3961)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044254.1"
                     /locus_tag="ASD48_RS29180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19585"
                     /product="hypothetical protein"
                     /protein_id="WP_057604730.1"
                     /transl_table=11
                     /translation="MSSSPARHRGIRKALATALLAALTPAAAAVPAVAVPAVATPTSAA
                     YAPVPPHNPYAGPDGTGTMHGDTGSSDTTPLAGPGAGTLTSTRAALASACPTVLIGYDG
                     YPVALCTPIFGQVPTVHLLDPDDGSSLATLQLTKGSLLGGVYAYLDHQDRLVVADGSRS
                     LLRVGHRQSASGAWQLSVDQRLSLASAIPSDDAVTGLSPDWQGRVWFATGGGVVGVADD
                     GTGTVRSLALPAGERVANSISTAPEGTAVTTTHATYLLTADAEGTPRISWRQAYDRGQA
                     RKPGLLSWGSGSTPTFLGPETGTDYVAIVDNADTTVHLKVYRTSTGAEICSVPVLQASG
                     GPGSENSPVGAGNSIFVAGTYGYPYPAVPDGAGDAVPASADFAGGLTRVDIRADGTGCT
                     QIWDNTLRSAAVPKLSTADHTLHTVLRDPVIPGSKGTSLLDTYRYAQIDAETGLVNRSR
                     SVGTGALYDTLQMAGTVAPDGAYLQGTVTGVLRITAG"
     misc_feature    complement(4524..4538)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.0"
                     /tool="antismash"
     gene            4529..4921
                     /locus_tag="ASD48_RS29185"
                     /old_locus_tag="ASD48_19590"
     CDS             4529..4921
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020131582.1"
                     /locus_tag="ASD48_RS29185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19590"
                     /product="YciI family protein"
                     /protein_id="WP_063887515.1"
                     /transl_table=11
                     /translation="MKYMIQMNVPAAQWDTIMSSYSKDDMAAMFAHMNSLNDDLMSAGE
                     WVDGQGLGGPSLVKTVRAGSDGRPQVTDGPAQAGHILAGYWVVDVKSEDRALEIAARAS
                     ACPGPGGKPGSDPIEVHAIPDDPTAA"
     misc_feature    4538..4551
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.41"
                     /tool="antismash"
     gene            <5208..>5301
                     /locus_tag="ASD48_RS45655"
                     /pseudo=""
     CDS             5208..>5301
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012336521.1"
                     /locus_tag="ASD48_RS45655"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /product="IS5/IS1182 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGCKRVRRHRYPRPAAGRTRGRDERSGPRRR"
     gene            complement(5386..5894)
                     /locus_tag="ASD48_RS45660"
                     /old_locus_tag="ASD48_19595"
                     /pseudo=""
     CDS             complement(5386..5894)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007500605.1"
                     /locus_tag="ASD48_RS45660"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19595"
                     /product="diadenosine tetraphosphate hydrolase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDNDWRTDRIGSALRGENPSVLRRLNAGFAAIGDAQFLPGYSVLL
                     VDDPKVENCRTWPGTSAWPSCPTWTNSEKQSSGHPVVWMRRSGGSIWRSSATPMGSCMR
                     TYGPGSSGSRPTWCECRCGSIPATGGPTSSTHSVHSTTRCARRSGTNWTVWLAELTARR
                     S"
     misc_feature    5983..5995
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            complement(6046..7515)
                     /locus_tag="ASD48_RS29195"
                     /old_locus_tag="ASD48_19600"
     CDS             complement(6046..7515)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435957.1"
                     /locus_tag="ASD48_RS29195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19600"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_057604731.1"
                     /transl_table=11
                     /translation="MTTAAIVGTGPNGLAAAVTLARAGLDVTLFEKADTIGGGLRSMPL
                     FDRDVTHDICSAVHPMAAASAFFRQFELPARGVRLLQPDMPYAHPLPQGAAAVAWRDID
                     RTARHLGQDGRRWTSLMAPLADRSDEVVGLFLSPQRSLPRSLAAPLLLARRVPAHTTSR
                     TPFTTQAARALLTGVAAHAVGKLPSLTSTAVALLLGHLAHSSGWPLPQGGSARIADAMA
                     ADITAHGGTIHTGHPIKDLAELSAFPLVMLDVAPKVFLDMAGPRHTLPTRYRNALRSYR
                     YGPGAAKADFLVNAPIPWSNPLVGKAGTVHLGGTRTDILRQETATAAGRRTDTPFVLVV
                     DPAVTDPSRACGDRTPVWAYAHVPHGDTRDPVDLIRRRIEEYAPGFTDTVIASRGLSAA
                     QYERYNPNYVGGDISAGALTLRQSLARPTPRWDPYTTPLPGVYLCSASTPPGPGVHGMC
                     GYFAALSALRRHHALHTPPDLSPKKGEGEVN"
     gene            complement(7512..9227)
                     /locus_tag="ASD48_RS29200"
                     /old_locus_tag="ASD48_19605"
     CDS             complement(7512..9227)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006132584.1"
                     /locus_tag="ASD48_RS29200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19605"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_057604732.1"
                     /transl_table=11
                     /translation="MNIRHIVRRQRLLLGLGALLGLSGTAAALTQPLLIGDLIEAVAAD
                     KSVAPPIALIAGLFAANALLGAAHAYLIGRAGENIVLDMRRTLTRRLLHAQLRAFNRLE
                     HGDIFTRTVSDTSLARVALSSSVAQMITAGFTSVGCIAAMAWIDWRMLLVTAVCLGITS
                     AAGLALARAVRTAAVMNREDTGHFGSGLLRALSALTTVKASRAEQREADRLQDLADTAR
                     TSGVRVTRLSALLVPVTNVGTQVSLAVVIAWGMARTATGALAIADLTAFIMYLFYLVSP
                     LVMLFMAIGEFQQGRAAIDRVSALADIDQEVSGQRSVPGDDMAPAVEFDQVTFAYAENT
                     APAVSGVSFSLPAAGVTAVVGPSGAGKTTLFQLIERFHIPDQGTIRVRGTDTAAMPLSE
                     LRSRIALVEQDAPLMRGTVRENLTYACPDASQSEILDAVEAAHLTGVIAGLPHGLDTEL
                     GEGGTGLSGGQRQRLAIARALLTRPDLLLLDEATAHLDSDSEAALRVAIGDIGTRCQVL
                     AIAHRISTAVAADRILVIEDGCLRATGTHTELMEHDATYRRLASRQLTAAGAGS"
     gene            complement(9224..9985)
                     /locus_tag="ASD48_RS29205"
                     /old_locus_tag="ASD48_19610"
     CDS             complement(9224..9985)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006132583.1"
                     /locus_tag="ASD48_RS29205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19610"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_057604733.1"
                     /transl_table=11
                     /translation="MPSTVQDIGYGRQFAPWYDRIFPKGAEAVATAEILSGLHPDPSAG
                     TLEFGVGTGRIAVPLSRKVGPVTGVDSSMEMLDLLASDPAGTDVIGIHGDIRNYTDSRH
                     YGLVYAVCSTLSMLLTAEDQQAAISRAAERLAPMGRLVIETSNRPAVEALHEGRARATL
                     FTPYPEPGTGLQTHSTLLPGSDLWQCSHIWYEADGTTRVGNELSRLTTPDEVDGYAVAA
                     GLTLEARYSNWDLSPYSDQYPMFLATYTKTA"
     gene            complement(10001..10591)
                     /locus_tag="ASD48_RS29210"
                     /old_locus_tag="ASD48_19615"
     CDS             complement(10001..10591)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     linaridin: cypI"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASD48_RS29210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ASD48_19615"
                     /product="hypothetical protein"
                     /protein_id="WP_057604734.1"
                     /sec_met_domain="cypI (E-value: 2.6e-30, bitscore: 101.0,
                     seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISTRKIPRTSPETSDLVTRGIEMALAAWLVATLLSQHPNRVFD
                     RLRPMSFIGNLIPNWRFFAPLPARHDFHVLYRTLTTSGEQSEWKAASSITPRSWSHTVW
                     FPKRRGEKAVFDLCFNLDAARGKRVELEKTVEFALLRGCVARSIEENDPVWPQLSGFQF
                     LIVRHSGYDTSQAPEYMFASPFIEVPAEVAQAS"
     gene            complement(10588..11583)
                     /locus_tag="ASD48_RS29215"
                     /old_locus_tag="ASD48_19620"
     CDS             complement(10588..11583)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (67-171). E-value:
                     4.6e-14. Score: 44.5. Matches aSDomain:
                     nrpspksdomains_ASD48_RS29215_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="ASD48_RS29215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19620"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_057604735.1"
                     /sec_met_domain="PF00561 (E-value: 2.3e-11, bitscore: 39.3,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 6.3e-20, bitscore:
                     68.2, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSRHDTLPRAFAGLLAGVAVTGFAAQALRHRRVLRGRGDESMFE
                     TSKGNILAYRMTEPTAPVSSETPVLVFETAMASTAEYWYWMELNLGLNYPTLVYSRAGY
                     GRSEFHEKEPFTLRSSVLDLEELVRHACGSRPVVIVGHSLGGYLALRAAEQMRDLVRGL
                     CLLDPSHPGELLRSSAQAKGAEHISFNLLLMPLSLRLGLGGLLEVPAWLKNFPADLQGL
                     CLDQYRDWKLWEAAKREWNATQQEFLGYNGELPKISVPTCLVSADRTHLTDKTVRELYS
                     ELAAGAPRSEMHVIERTAHDELLFRKEVFHLIGQFGESLEADRAEAGEAS"
     aSDomain        complement(11071..11382)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS29215_Abhydrolase_1.1"
                     /evalue="4.60E-14"
                     /label="ASD48_RS29215_Abhydrolase_1.1"
                     /locus_tag="ASD48_RS29215"
                     /protein_end="171"
                     /protein_start="67"
                     /score="44.5"
                     /tool="antismash"
                     /translation="PVLVFETAMASTAEYWYWMELNLGLNYPTLVYSRAGYGRSEFHEK
                     EPFTLRSSVLDLEELVRHACGSRPVVIVGHSLGGYLALRAAEQMRDLVRGLCLLDPSHP
                     "
     CDS_motif       complement(11116..11184)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS29215_0001"
                     /evalue="1.10E-06"
                     /label="NRPS-te1"
                     /locus_tag="ASD48_RS29215"
                     /protein_end="156"
                     /protein_start="133"
                     /score="21.1"
                     /tool="antismash"
                     /translation="SRPVVIVGHSLGGYLALRAAEQM"
     gene            complement(11580..12464)
                     /locus_tag="ASD48_RS44465"
     CDS             complement(11580..12464)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASD48_RS44465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157880721.1"
                     /transl_table=11
                     /translation="MKPRINSLLGKLVSPPSIGRDRALTVMEQTSAVTHLIHSLENLAS
                     ARDRQPGGLNHWDEVREIHAARHPLVRRAIDVLADPRSVRTIHIARVLAAASLLAPSAP
                     RRLRAAANSMLALTSMANNLTQPYGNDGTDQLSFHVEAAAAIARTSGKPRLIDACLWYV
                     ALQSTMSYAAAGYAKLPSDIWRSGDALPGILRTESFGEPKAYEMAQRHPTLTKLTAHSV
                     LALECAFPVVFLAKGRPAPLMLATLGMFHLANARVMGLGRFVWAFTSTYPAVLYAAQRR
                     PVAPAALASGRSS"
     gene            complement(12582..12749)
                     /locus_tag="ASD48_RS44470"
     CDS             complement(12582..12749)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASD48_RS44470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_157880722.1"
                     /transl_table=11
                     /translation="MDSLTSIVNHDERLDALHIASTQTEILSETTVPVLGTPAALAASV
                     AVATAIHSIW"
     gene            complement(12843..13040)
                     /locus_tag="ASD48_RS29225"
                     /old_locus_tag="ASD48_19630"
     CDS             complement(12843..13040)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASD48_RS29225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ASD48_19630"
                     /product="hypothetical protein"
                     /protein_id="WP_157880723.1"
                     /transl_table=11
                     /translation="MSPVLEMVNASEEIGSLPMDITESIHGDLDPGMFISLSDAVNTAL
                     AVCGLPAHAAVHCAVAALTH"
     misc_feature    complement(13227..13242)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 16.03"
                     /tool="antismash"
     misc_feature    complement(13308..13324)
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 20.82"
                     /tool="antismash"
     gene            complement(13628..14767)
                     /locus_tag="ASD48_RS29230"
                     /old_locus_tag="ASD48_19635"
     CDS             complement(13628..14767)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131966.1"
                     /locus_tag="ASD48_RS29230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19635"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_057604738.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.5e-23, bitscore:
                     77.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 4.5e-24, bitscore:
                     80.0, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.4e-51, bitscore:
                     170.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSRLTPQQSDFAAAVREFAQRECGSPVQRDALTQGGREPHNPKI
                     YAMLADLGWLGVCLPEEYGGAGGGLADACVFLEETSYGLVPAGGFVTTVITAKVYERFG
                     TEEQRRAVLGGAARGQVLAVAMSEPGAGSDVAALRCRAERQPDGSWLVEGQKTWISNAH
                     VAESMLLVARTGGDRHEGLTMFHVPMNTPGVEVRGIETMGGREVNDVFLTGVRLPPDAV
                     VGEVGSGWRQLMAGLNHERLFLAANMLGLGRRAFDDAVAYIREREQFGRPVGSFQALRH
                     RVADLATEIECARLLVREVASDCDARPDRLFPREASMAKLKATETAKRVALECMQMMGG
                     YGYATEYGMERHLRAAVVSTVYGGTSEIQRDIIGKSYGL"
     misc_feature    complement(14831..14847)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 17.69"
                     /tool="antismash"
     gene            14879..15505
                     /locus_tag="ASD48_RS29235"
                     /old_locus_tag="ASD48_19640"
     CDS             14879..15505
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979007.1"
                     /locus_tag="ASD48_RS29235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19640"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_057604739.1"
                     /transl_table=11
                     /translation="MKTSANDSLLARAIARPETEEKLARQILDAALEQFTTFGLRRSSV
                     EDVAKRAGVSRVTVYRRFQSKDGLVEACLLREGSRFFQELDSAVASLPTMEDRVVEGFV
                     VALRHTRAHPLFGGLLKLEPEVVLPYFTVQGGASLAATTDYLTAHLRRAQHTEGRPETD
                     PRPVAELMVRVAVSFLLNPAGCIELGDEEQARAFARRYLAPLLDA"
     gene            complement(15520..17268)
                     /locus_tag="ASD48_RS29240"
                     /old_locus_tag="ASD48_19645"
     CDS             complement(15520..17268)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127354.1"
                     /locus_tag="ASD48_RS29240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19645"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_057604740.1"
                     /sec_met_domain="Aldedh (E-value: 3.5e-122, bitscore:
                     403.6, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHTTENADRPGGATGPGSTDTAGQPDPATTGPAGHTEPAAADTS
                     GLTEPAPTDTSGPTAPGSTDTAAPTEPGSTADGTRADSVERRTSPPGSFTSRSPVTGEA
                     LAAYPVHGPLDVDRAVRRARAAGTRWAALSAGKRRGHLLRWKRELASSLDTVAGIVAAE
                     TGKPRQDAELELLLTLEHLSWAARNAGRVLRRRRVRSGAVAMHQAATVVRRPLGVVGVI
                     GPWNYPVYTPMGSIGYALAAGNAVVFKPSEYTPGTGVLLAELFDAAVPGYAGLFTVVTG
                     AAATGGALARSGVDKVAFTGSPGTARKVMAVCAESLTPFLAECGGKDAVIVTAGADLDA
                     AADAIVWGAMGNAGQTCAGVERVYAVRQVHAALCEKVVERARGLRPGAGPDAAYGPMTM
                     PDQTAVVRRHVQDALAAGAGAALGGSESAPAAGAFVEPVVLVDVPEDSPAMTEETFGPT
                     VAVNAVADEDEAVRRANASRYALGAAVFGGSRRAGAALASRLRAGAVSVDSVLGFAAVP
                     ALPFGGSGDSGFGRIHGADGLRAFTTPQSVTVRRFAPPVDLTSFATPAATKARAVALMR
                     WLHSRR"
     gene            complement(17265..18158)
                     /locus_tag="ASD48_RS29245"
                     /old_locus_tag="ASD48_19650"
     CDS             complement(17265..18158)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127355.1"
                     /locus_tag="ASD48_RS29245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19650"
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_057604741.1"
                     /transl_table=11
                     /translation="MGRYSRLERIRRMDPRHDHEEIFRWITRYEFPWDYMQGVSVAFLR
                     DYGVPRISQLLDRTQEFERAGQKRYDDTVLIAYEMVRHGMDSPHGRATARHLNRIHGRY
                     RIPNEDYLYVLATTVVGPKRWIDRYGWRPLCPQEAESLALVGRRMGEMMGITDLPADYA
                     GFEQLHDTYEKEMFAYDPANRRVAAATLRIITDWYPRPLRPLVARLALAVLDETLLTAL
                     GFRPQPRPVRTAAHVLLRTRALLTRHLPARPGWWPSRPKPRSYPFGWTLDDLGPHWAHH
                     RPPTPLADENPPMERR"
     gene            complement(18210..19865)
                     /locus_tag="ASD48_RS29250"
                     /old_locus_tag="ASD48_19655"
     CDS             complement(18210..19865)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039352.3"
                     /locus_tag="ASD48_RS29250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19655"
                     /product="DUF6114 domain-containing protein"
                     /protein_id="WP_057604742.1"
                     /transl_table=11
                     /translation="MFAFVLGFLSELARETGDWIDRVLPARRVRRSLRAWRRRRPFWAA
                     VWVIAGGIEMVAIPLAPLPLMIRVGVGAMSAAGIAVVLVAGGIFFLFKPDQRMFVSVVT
                     AVASLTSMATTNLGGFGIGMLAGLIGSSMAFGWMPGNRHPEEGPREPQTPQGPASARPA
                     STQPASAQPAGAAARAERTTGATAGAERTADAPAAGDGASGRPKADEGRARYRGRRAGA
                     RGAVLFVLTTALAAAMLPGATGAAAHPGTGLFPLPWPTNGWPWEWGSGDTSSTAPSATP
                     SESPAAEAGPSPTGSASPGATPGPSTGPSAGPNASPSAGSDSAPDSSGGDADQGGGPDD
                     GAGTEGPADRPGAVLGPQVTLPCLTGVDTGGLPNPEPGEMPADPDDLTALRPPVVVGDQ
                     PGRPRAAYPVNTVYPQVGADSLTAYGAIVHGATYLGTVGGGQLKVLWVHADRLVADDYT
                     FRLETPGQVQTIDVDLDIPQVDIYVTRLSGSLTIPVIDVATPRICIGADVVPANLPIAV
                     QLPELSVTAVEAGQVLVDAETVNFSGLSAHSHTR"
     gene            complement(19890..20516)
                     /locus_tag="ASD48_RS29255"
                     /old_locus_tag="ASD48_19660"
     CDS             complement(19890..20516)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016573298.1"
                     /locus_tag="ASD48_RS29255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_19660"
                     /product="DUF6230 family protein"
                     /protein_id="WP_242432766.1"
                     /transl_table=11
                     /translation="MRDRYAHIGNADEGRTHWRRSALMFVPCTLAVGALGIALAEGAIA
                     ASFAVSGTAFKVSASEVTAQGVSSFPSSIGGSADDARPVLLAAVKDGTVSDVCVSLKQK
                     LPLVGEISMLVHSGADKPLAGTNLVVNADALTGGGGKVTGVQAGRDASTLTGAPGVTGP
                     KGVFGVQADTAVAHDLRSTAYSANGGTLTLEKLEIEFSRSGKQCF"
ORIGIN
        1 cccgaaccgt gcccagttct cgtggaacgc ggccgcgggg acggtcggcc tcaactggca
       61 gaccgcctgg aagcagccgt ccatcgacat ggccaagacg atcttcgaca agatcaacgc
      121 caaggagggg acgatctacc gcaccgacct cttcggcgcc tacaagatct ggggcgacca
      181 cctgacgtac caccccctcg gtggcgcggt gctcaacaag gcgacggaca actacggccg
      241 cctgcacgga cacccgggcc tgtacgtcat cgacggcgcc ctcgtcccgg gcaacaccag
      301 cgtcaatccg ttcgtcacca tcaccgcact cgccgaacga aacatagaag cgatcatcgc
      361 cgcggatctg taggggtgac ccgagcgcgt gctgtccgga actgcacgga ccccgtcccg
      421 ggagagggag gagagcggaa cgagcagaac gacaggggac tgagcaggga acgacagggg
      481 actgagaacg acagagtact gagcagggaa cgaatgagca ctgagaaaga agcgtcaggg
      541 gactgagcaa ggaacggacc cagggccgcc cggactcgcc ggacggcccc ggaccggctc
      601 agtgccccgg cagcacacac atggcgtcga gccccagcac ccgattgagc cgcccgaacg
      661 ccagccacga gccgaggctc atggtcagct ccacgatctc cgtctggctg tagtgcgcgg
      721 tcatccggtc ccagaactca tcgtcgaggc cgtggtgatc cagggcgtac ctctccgcgt
      781 actcggcggc caggcgggtg cgctcgtcga aggcgtcggt cgtgcgccac tcggcgaccg
      841 cgtcggcgaa ctcctcctcg accttctgct cgtcccgctc ggtccgccag tcgaggcaga
      901 agagacaccc gttgatctgc gcgatccgga gccgcgccgc ctcgaactcg cggagtccca
      961 gggtcgtatg ggcgtagacg gacagcgaga agttcgcggc ggcgagcccg atgccgggga
     1021 ccatgtcgcc ccacacgtac tcgatcgggt tcctgccttc ggggatgtcg aggttcatcc
     1081 gggactcctt cgtgttcgcc cctggccccg gccggtgaca ggaggcgcgt cctcgtggtg
     1141 tcgcagggac acggaaaggg gcgtcggcgt cacttcccgc cgagccttcc caccgccggc
     1201 cgcagcggga cgtcgagcgc gtcgtacagt ccgggctccg cgtccacgag ccagtcgatg
     1261 gcgccgacca gccggccgac cgcggtggca ttcccgcccg cggaccggtt ctcgccctcg
     1321 tcggtcgcct cgacggtgac ctcgatgcga ggacggccct cgatgatcac ccggtgcgcc
     1381 ccgtcgccgt tgggcggtga cggccagtcc ggggcgcagg acgggtggat ccgggtgatg
     1441 tgctcgatga cgaggcgggg ttcccccttc acgaagccct gcacctcgaa ccgcaccgcg
     1501 ccctgggtgc ccgcctcgaa ctcgcccatg gtccgggtgc tcaccgtcgc gtcgagcgca
     1561 cggcgctgca aggtctcgcg gatctcgtcg agttcgacac cgagggccct ggccatcagc
     1621 cgaatctgcc cgccccacac catggtcggg atcgacgggg cgagcatcag cggctcgtag
     1681 tccatcggct ggcccattcc gaccagatac ctgaccgact cctcctgctc gtacgtggag
     1741 tagtcgaaga tctcctggca gcggacggcg tcgacgacgg tgcccaggcc gctcatgagc
     1801 aggggcagta cgtcattgcc ccagcccggg tcgacgccgg acacgaacaa cgaccctccg
     1861 ccgtcggcta tcgcggcgag cacggggtcc cggaactcgg gtggggcgtt gcgctggtcg
     1921 tagagcgggt acaacgccgg agtgacgacc acggcacccg cccggatcgc cgcgccgatg
     1981 tcggccagcg cctcgtcggg ccggatgtcg cccgacgccg cgtacaccac cgccccaggg
     2041 ccttcgctca gcacggcggc gatgtcgtcg gtcgccgaga tgcccaggcc ccggccgagg
     2101 ccgccgagtt cccccgcgtc gcgcccgacc ttctcggggt tgtggacgag cacggccgcg
     2161 agatcgagcg ccggatgcgc ctcgaccgca cggatcgccg cacggccgac gttgcctgta
     2221 ccccagacca ccgtggaaat catacgcggg agcgtaatct gacgagccgt cagtttccat
     2281 acccttgcac cggactcacg gcatgcccgt ggaccgtgga gtgactcgag ttcgcgcgcg
     2341 accacggtgt cgggcgatgc gggcgaacga gcctcctgag ttcgtgccac gtcagcgggc
     2401 cgtctgctcg gacgaaacga cgcgacgacg cccgcctccc gggggaccgc gggaggcgcg
     2461 gctcaggtcc ggctcacccc gcggtgatcc gcagtacccc ggtcaccgtg ccctggaggt
     2521 aggcgccgtc cggggcgacg gtgccggcca tctgcaacgt gtcgtacagc gcgccggtgc
     2581 ctacgctcct ggaacggttg acgagtcccg tctcggcgtc gatctgcgcg tagcggtagg
     2641 tgtccagcag gctggtgccc ttgctgccgg ggatcaccgg gtcgcgcagg accgtgtgca
     2701 gggtgtggtc ggccgtggac agtttcggta cggccgccga gcgcagggtg ttgtcccaga
     2761 tctgggtgca gccggtgccg tcggcccgga tgtccacccg ggtcaggccc ccggcgaagt
     2821 cggcggaggc gggcacggcg tcacccgccc cgtcgggcac ggcagggtac ggatatccgt
     2881 acgtgcccgc gacgaagatg ctgttcccgg caccgacggg cgagttctcg ctgccggggc
     2941 cgccggacgc ctggaggacc gggaccgagc agatctccgc gccggtggag gtccggtaga
     3001 ccttgaggtg gacggtggtg tcggcgttgt cgacgatcgc gacgtagtcg gtcccggtct
     3061 caggtccgag gaacgtcgga gtggagccgc tgccccagct cagcaggccg ggcttgcggg
     3121 cctgtccacg gtcgtacgcc tggcgccagg agatcctggg cgtgccctcg gcgtccgcgg
     3181 tgagcagata ggtggcgtgg gtggtggtga cggcggtgcc ctccggcgcg gtggagatgc
     3241 tgttggcgac ccgttcaccg gccggcaggg ccagggaccg aaccgtgccg gtgccgtcgt
     3301 cggcgacgcc gaccacacca ccgcccgtgg cgaaccagac gcggccctgc cagtccggag
     3361 acaggccggt caccgcgtcg tccgagggga tggcagacgc cagggagagt ctttggtcga
     3421 ccgacaactg ccaggcaccg gaggcacttt gacggtgccc gacgcggagc agactgcgac
     3481 tgccgtccgc gacgacgagc cggtcctggt ggtccaggta ggcgtagacc ccgcccagca
     3541 gcgagccctt ggtcagttgg agggtggcca gggaggatcc gtcgtcgggg tcgagcaggt
     3601 gcaccgtcgg gacctgcccg aaaatggggg tgcacagggc cacgggatag ccgtcgtagc
     3661 cgatcagcac ggtggggcag gcggatgcga gcgctgcccg tgtcgacgtc agggtgcctg
     3721 cgcccggacc ggcgagcggt gtggtgtcgg aggagccggt gtcaccgtgc atggtgcccg
     3781 taccatcagg tccggcgtag ggattgtgcg gcggaaccgg ggcgtaggcg gcggaagttg
     3841 gtgtcgcgac ggcgggtacc gcgactgcgg gtaccgcggc ggcggccggc gtgagagccg
     3901 cgagcagggc ggtggccagc gctttgcgga tgccgcggtg gcgggcgggc gaagaggaca
     3961 tggcgaggac aggatccttc cgtgcgacgg agatccgtac tgggtgtcgg ggcagtgcgc
     4021 gcgagggcac gcggccggag ccggccggac ggatgcgtcg gcctgggcgg acatggctgc
     4081 gtgcgaccgg ggctgctacg gggatgcggc ggaagccggc agcgtcaagg ggcggtggtg
     4141 cctggaacgg cagccgtcgg ggtcagagcc cgtgctgaca gagggcgccg gaggttcgcg
     4201 cgagatcgac gtggtgtcgg cgcgtgagaa cccggcacag agacttcatg tccatgatcg
     4261 aagcagcttc gtacgggcat ggtcaagtgc agaccgccga tcgtcccgcc gtggcgggac
     4321 agcgcgcctc ggcggcgaca gaccgttgtg gggcggccgt aggtcctcgt cgtcctccgg
     4381 cctgcggagg tggcggacga ggcgggcctc gcctcgagcg gtagggggaa gccctcgtcg
     4441 gagggcaccg atgagttttg cggctgccgc ccgtctacct ctctgcaagc ctcagaagcg
     4501 cagcggctac ccgggaagtg tgaggaacat gaagtacatg atccagatga acgtgcctgc
     4561 cgcccagtgg gacaccatca tgtcgtcgta ctccaaggac gacatggcag ccatgttcgc
     4621 tcatatgaac tccctcaacg acgacctcat gtccgccggg gagtgggtgg acgggcaggg
     4681 cctcggggga ccctcgctgg tcaagacggt gcgggccgga agcgacggac ggccgcaggt
     4741 gaccgacggg ccggcccagg cggggcacat cctggccggg tactgggtgg tcgacgtcaa
     4801 gagcgaggac cgggccctgg agattgccgc acgagcgtcg gcgtgtcctg gccctggtgg
     4861 gaagcccggc agcgacccga ttgaggtgca cgcgatcccc gacgacccga cggcggcctg
     4921 accgaccgtg tgtggcggcg tccgggaacg ggcgagccgg gagctgggag ccgccgccac
     4981 cgagctgcag gagcacctcg ccgaaaggcg cgatgacgat gacgggaggt gcccgccgat
     5041 cgagtgatcg acgggcctcc ggatcgcctc gccctggtgg cccggttgac gagcatcacc
     5101 aatccgccat ccccgatccg cgcattgcgc agttccggat ccatggtgag cggggctcgg
     5161 ggacgaggtc cggtcgagcg gccgcattcg gcgcaggcaa gaacgccaag ggctgtaagc
     5221 gggttcgtcg tcaccgatac cctcggcctg ctgctggccg tacacgtggt cgcgacgagc
     5281 gttcaggacc gcgacggcgc ccgccgaccg cttctgtgga gccgcctcga ccactcgggt
     5341 gtatggaaga tctgggccga tcggggcttc gccgatcgcc aggactcaag acgaccgctt
     5401 cacgatctgc gtgctgtcag ctcggcgagc cagacggtcc agttcgtccc cgatcgcctt
     5461 gcgcagcggg ttgtgctgtg gaccgagtga gtgctgcttg tcggtccacc tgtcgcgggg
     5521 atagagccac accggcattc gcaccaagta ggccggctcc cactcgaacc ggggccatac
     5581 gtgcgcatgc aggaacccat cggcgttgcc gaggatctcc agattgaccc gccggaacgc
     5641 cgcatccata cgacgggatg cccgctcgac tgcttctccg agttggtcca tgtcggacaa
     5701 gaaggccagg cgcttgtccc tggccaggtc cgacagtttt ccactttggg atcgtccacc
     5761 aggagcaccg agtagcccgg gaggaattgc gcatcgccga tcgccgcgaa ccccgcgttc
     5821 aagcgccgta gaactgacgg gttttcgcct cgcagggcgc tcccgatccg atccgtccgc
     5881 cagtcattgt ccatggccgg gaacctaccc ggtcgcgatc accaccccgc ctggggatgt
     5941 cggggcatcc cgtctcaggc gatcgtctac tcgggctcac agttgccgct gtcactgccg
     6001 gcttctcctg ccgatcacgg ccctctcgct tcgacggtgc aggcatcaat tgacctcccc
     6061 ttctcccttc ttgggggaga ggtccggtgg ggtgtgcagg gcgtggtggc ggcggagcgc
     6121 ggagagagcg gcgaagtagc cgcacatgcc gtggacgccg gggccggggg gcgtggacgc
     6181 tgagcacaga tagacgcctg gcagtggtgt ggtgtagggg tcccagcgag gggttggccg
     6241 ggccagtgac tgacgcagcg tcaaggcgcc tgcggagatg tctccgccga cgtagttcgg
     6301 gttgtacctc tcgtactggg cggcggacag cccgcgggag gcgatgaccg tatcggtgaa
     6361 gccgggggcg tactcctcga tgcgccgccg gatcaggtcg acggggtcgc gtgtgtcccc
     6421 gtgaggcacg tgggcatagg cccataccgg tgtcctgtcc ccgcaggcgc gggacggatc
     6481 ggtgaccgct gggtcgacca cgagcacgaa gggggtgtcg gttcggcggc cggccgcggt
     6541 cgcggtctcc tgacggagga tgtccgtgcg tgtaccgccc agatgcacgg tgccggcctt
     6601 gccgacgaga gggttggacc aggggatcgg agcgttgacg agaaagtccg ccttggccgc
     6661 gcccgggccg tacctgtagg acctcagtgc gttgcggtag cgcgtgggca gcgtgtgccg
     6721 gggtccggcc atgtcgagga agactttggg agcgacgtcc agcatgacga gggggaaggc
     6781 gctgagctcg gcgaggtcct tgatggggtg accggtgtgg atggtgccgc cgtgtgcggt
     6841 gatgtctgcg gccatggcgt cagcgatgcg ggcgctgcct ccctgaggga ggggccagcc
     6901 gctgctgtgc gcgaggtgac ccagcagcag ggcgaccgcc gttgaggtca gcgagggcag
     6961 ttttcccacg gcgtgggcgg cgactccggt cagcagggcc cgtgccgcct gcgtggtgaa
     7021 gggcgtacgg gaggtggtgt gggctggaac gcgccgtgcc agcagcagcg gcgcggccag
     7081 actgcggggc agagagcgct ggggggagag gaagaggccg acgacttcgt cggagcggtc
     7141 ggccaggggc gccatgaggc tcgtccaccg tcgtccgtcc tggccgaggt gacgggcggt
     7201 gcggtcgatg tcgcgccagg ccacggctgc tgcaccctgg ggcagggggt gggcgtaggg
     7261 catgtcgggc tgcagcagtc ggacgccacg ggcgggcagt tcgaactgcc ggaagaacgc
     7321 ggaggcggcg gccatcgggt gaacggcaga gcagatgtcg tgcgtcacgt cccggtcgaa
     7381 cagcggcatg ctgcgaagac cgccgccaat ggtgtcggcc ttctcgaaca gcgtgacgtc
     7441 gagtccggcg cgggcgaggg tgacggcggc ggccaggccg ttggggccgg tgcccacgat
     7501 ggcggcggta gtcatgaacc ggcccccgca gcggtgagct gtcggctggc caggcggcgg
     7561 taggtggcgt cgtgctccat cagctccgtg tgcgttcctg ttgctcgcag gcagccatct
     7621 tcgatgacca ggatccggtc ggctgcgacg gcggtggaga tgcggtgcgc gatggccagg
     7681 acctggcagc gcgtgccgat atcgccgatg gcgacgcgca gcgccgcttc ggagtcggag
     7741 tccagatggg cggtggcctc gtctagcagc agaagatcgg gccgggtcag caacgcgcgg
     7801 gcgatggcga ggcgttgtcg ctgcccaccg gacaggcctg taccgccttc gccgagttcg
     7861 gtgtccagtc cgtgtgggag gcctgcgatc accccggtga gatgggcggc ctccacagca
     7921 tcgaggatct cgctctgtga ggcatcgggg caggcatagg tgaggttctc gcgaacggtt
     7981 ccccgcatca ggggtgcgtc ctgttccacc agggcgatgc gagagcgaag ctcgctcaga
     8041 ggcatggcgg cggtgtccgt tccacggacg cggatcgtgc cctggtcagg gatgtggaag
     8101 cgttcgatga gctggaagag ggtcgtcttg ccggcgcccg acgggccgac gacggcggtt
     8161 acaccggccg ccggcagcga gaaggacact cccgagacgg cgggagcggt gttctcggcg
     8221 taggcgaagg tgacctggtc gaactcgacg gcaggggcca tgtcgtcgcc gggcaccgag
     8281 cgttgtccag agacttcctg gtcgatgtcg gccaacgcgc tgacccggtc gatcgcggcc
     8341 cggccctgtt ggaattcgcc gatggccatg aacagcatga ccagcggcga caccaagtag
     8401 aacaggtaca tgatgaacgc ggtgaggtcc gcgatcgcca gggcgccggt ggcggtgcgg
     8461 gccatgcccc aagcgatcac cacggcgagg gacacctggg tgccgacgtt cgtgacaggc
     8521 accagcaggg cggacagccg cgtcacccgg accccgctgg tacgtgcggt gtccgcgaga
     8581 tcctggagac ggtcggcctc acgctgctcg gcgcgggaag ccttgacggt cgtcagcgcg
     8641 ctcagggccc gcaggaggcc ggagccgaag tggccggtgt cttcccggtt catcacggcc
     8701 gcagtgcgga cggcgcgggc cagggcgagt ccggcagccg aggtgatgcc aaggcatacg
     8761 gcggtgacca ggagcatccg ccagtcgatc catgccattg ccgcgatgca gccgacgctg
     8821 gtgaagccgg ccgtgatcat ctgtgcgacg gaggaggaca aggccacgcg ggccagagag
     8881 gtgtcggaga cggtgcgagt gaatatgtcc ccgtgctcga gccggttgaa tgctcggagt
     8941 tgagcatgca gaaggcggcg ggtgagcgtc cttcgcatgt cgaggacgat attttctccg
     9001 gcccgcccga tgagataggc gtgggcggcg ccgagcagcg cattggctgc gaacaggccc
     9061 gcgatgagag cgatgggcgg tgccacggac ttgtccgcgg cgacggcttc gatcaggtcg
     9121 ccgatgagca gcggctgcgt gagggctgcc gctgtgcccg acaggccaag aagcgcaccg
     9181 aggccgagga gcagccgctg ccgacggaca atgtggcgga tgttcatgcc gtcttggtgt
     9241 aggtcgccag gaacatcgga tactgatcgc tgtacgggga caagtcccag ttgctgtaac
     9301 gggcttcgag cgtgagcccg gcagcgacgg cgtagccgtc gacctcgtcc ggagtggtca
     9361 gccgggacag ttcgttgccc acgcgtgtcg tgccgtcggc ctcgtaccag atatgggagc
     9421 actgccacag gtcggagccc ggcaggagtg tggagtgggt ctgcagtccg gttcccggct
     9481 ccgggtaggg cgtgaacaac gtggcgcggg cccggccctc gtgaagggcc tcgaccgcgg
     9541 ggcggttgct cgtctcgatg acaagtcgtc ccatgggagc gagccgttcg gccgcccggg
     9601 agatcgcggc ttgctggtcc tcggcggtga gcagcatcga cagggtgctg cacacggcat
     9661 atacaaggcc gtagtgacgt gaatcggtgt agttgcgaat gtctccgtgg atgccgatga
     9721 cgtcggtgcc ggcgggatcc gaagccagca gatcaagcat ctccatcgaa gaatccacac
     9781 cggtgaccgg gcccaccttg cgggacaggg ggacggctat gcgcccggtc cccaccccga
     9841 attcgagggt gccggccgac gggtcggggt ggagaccgct gagtatctcc gccgtagcca
     9901 ccgcttccgc tcccttgggg aagatgcggt cgtaccaggg cgcgaactgg cggccgtagc
     9961 caatgtcttg aacagtgctg ggcatggtat tcaacggatc ctaactggcc tgtgcgactt
    10021 cggccggcac ctcgatgaac ggtgaggcga acatgtattc cggggcctgc gaggtgtcgt
    10081 acccactgtg tcggacgatc aggaactgaa agccggagag ctgcggccac acgggatcgt
    10141 tttcttcgat gctgcgggcc acgcatccac gcagcagggc gaactcgacc gttttttcca
    10201 gttcgactct tttccctctg gcggcatcca gattgaaaca gaggtcgaag accgctttct
    10261 ctccgcgccg tttcgggaac cacacggtgt ggctccagga acgcggagtg atggacgatg
    10321 ccgccttcca ttccgactgc tctcctgacg tcgtcagggt gcggtagagg acgtgaaagt
    10381 cgtggcgagc cggaagcggg gcgaagaacc gccagttggg gatcaggttc ccgatgaagc
    10441 tcatggggcg gaggcggtcg aagactcggt tggggtgttg gctcaggagg gtggccacca
    10501 gccatgcggc aagggccatc tcgataccgc gcgtcaccag atcggatgtt tcgggcgagg
    10561 tgcgggggat tttacgtgtg ctgatcttca cgaggcctca cctgcttcag ctcgatctgc
    10621 ttcgagactt tcgccgaact gtccgatcag atggaacacc tcctttcgga agagcagctc
    10681 gtcatgcgct gtccgctcga tgacgtgcat ttcggaacgg ggtgccccgg ctgccagctc
    10741 gctgtacagt tcgcgcacgg tcttgtccgt cagatgcgtg cggtcggctg acacgagaca
    10801 tgtaggaaca ctgatcttcg ggagctcgcc gttatagccg agaaactctt gctgggtcgc
    10861 gttccattcc ctcttcgctg cttcccagag tttccagtca cgatactgat cgagacagag
    10921 tccctgtaga tccgcaggga aattcttcag ccatgccggc acctcaagca gtcctccgag
    10981 gcccaaacgg agcgagaggg gcatgaggag aagattgaag gaaatatgct ctgccccttt
    11041 cgcctgagcg gaagagcgca gcaactcgcc tgggtggctc ggatccagca ggcagagacc
    11101 gcgaacgagg tcgcgcatct gctctgccgc gcgcagtgca agatacccgc cgagcgagtg
    11161 gccgacgatc accaccggac ggctgccgca ggcatggcgg acgagctcct ccaagtccag
    11221 cacggaggat cgcagggtga acggctcttt ctcgtggaac tcgctgcgtc catagccggc
    11281 ccggctgtag acaagtgtcg gataattcag gccgaggttg agctccatcc aataccagta
    11341 ctccgctgtt gaagccatcg cggtttcgaa caccaggacc ggggtttcgg aggaaaccgg
    11401 agcagtcggc tccgtcattc tgtaggcaag gatgtttccc ttgctcgtct cgaacatcga
    11461 ctcgtcgccg cggccgcgca agactcggcg gtgacgcagc gcctgggctg cgaatcccgt
    11521 cacggcaacg ccggccagca ggcctgcaaa ggcgcggggg agggtgtcgt gacggctgtt
    11581 cacgaagacc tccccgaggc gagggcggcc ggggccacag gtctgcgctg tgctgcgtac
    11641 aggaccgcgg ggtaggtgga ggtgaaagcc cacacgaaac gaccgagacc catcactcgg
    11701 gcgttggcca ggtgaaacat cccgagcgtg gcgagcatca ggggagccgg cctgcccttg
    11761 gcgagaaata ccacagggaa ggcgcattcc agagccagta cgctatgggc cgtcagtttg
    11821 gtcagagtgg ggtgacgctg ggccatttca taggcctttg gctcaccgaa ggactccgtc
    11881 cggagaatgc cgggcagggc atcgccggat cgccagatat cgctgggcag cttggcgtat
    11941 ccggcggcgg catacgacat ggtcgactga agagccacat accacaggca cgcatcgatc
    12001 aatcgtggct tgccgctcgt cctcgctatc gcggctgccg cctccacgtg aaagctcagc
    12061 tgatccgtgc cgtcatttcc gtacggctgt gtcagattgt tcgccatgga ggtcaacgcc
    12121 agcatgctgt ttgccgcggc ccgaaggcgt cgaggtgcgc tcggggccag tagtgacgcg
    12181 gcggcgagca cgcgggcgat gtgaatcgtc cgaacactac gcggatctgc gagcacatcg
    12241 atcgcgcggc gaaccaacgg gtgcctcgcg gcgtgtatct cacgcacctc atcccagtga
    12301 ttcaaaccgc cgggttgccg gtcccgtgcc gaggcgagat tctccaggct gtggatgagg
    12361 tgagtaacgg cactcgtctg ttccatgacg gtgagggcac ggtcgcgtcc aatggaagga
    12421 ggcgagacca acttgcccaa aagagaattg attctgggtt tcatatttca ccatgctttt
    12481 gcgacagaat gcaccacgag gtgggccgtg cccatgagac acgggcacgg cccatttctt
    12541 tcggagaaac tcaccgcggc ctttcgacct gagtgattag atcaccagat cgagtgaatc
    12601 gccgtggcga ccgcgaccga ggccgcgagt gctgccgggg tgcccagaac gggaaccgtg
    12661 gtctcgctca gaatctccgt ttgcgtcgac gcgatgtgaa gcgcgtcgag cctctcgtcg
    12721 tggtttacga tcgaggtcag ggaatccatt tgcttacctc tctgagtgtg tctgatcgaa
    12781 cccgtccgct cggtggtccg cgaagcagcg taattctgct gcaagcagga cggagggggt
    12841 tatcagtggg tgagagccgc cacggcgcag tgcacggccg catgcgccgg cagcccgcaa
    12901 acagccaggg ctgtgttgac ggcgtcgctg aggctgatga acatgccggg atccaggtcc
    12961 ccgtggatac tttcggtgat gtccatcggc agagagccga tttcttcgga agcgttcacc
    13021 atctccagca caggagacat gattaacctc ttttccgttg cgtctgcacg gaaagattcc
    13081 atggaaatgg gcggcaactg gcaactggca actccgcgag tcgtcagttg agccgttccc
    13141 ctctggtcag gaggggagga tcgactcggc ccatacagaa tcccccgttg atcaatagaa
    13201 cattaacgcg ggcacaggga tgagtctgtg gtgtggatca cagcgacttt ggcatggggc
    13261 gagagaaaga ccctcgaaag gcgctcggcg taatcctcgt caagttcttg caggtgacat
    13321 gcagtccgtg cgtgtcggta gttgtgcaac tctttacagg atggccgaaa cccttgaggg
    13381 cggggctgaa acgctggcct tgatcatcga agatggccgg gtgtatatgg agtgtcaccc
    13441 ttgaagtggc cgccatgtcc gacaatcgaa ttgcttggtg gttcgcctgc aatgtccgcc
    13501 tgtcacgcca gggcttacgt atttgccgtg cgacgccgga tggagggagt gcggaggtga
    13561 ggacgcgccc cggcccggga agggcagggg cggccgtcgg cctcgtggcg tccggagccg
    13621 ggccggctca gaggccgtag ctcttgccga tgatgtcccg ctggatctcg ctggtgcccc
    13681 cgtagacggt ggagacgacg gcggcgcgca gatgccgttc catgccgtac tcggtggcgt
    13741 agccgtagcc gcccatcatc tgcatgcact ccagcgcgac gcgcttggcc gtctcggtgg
    13801 ccttgagttt ggccatcgac gcctcgcgcg ggaagagccg gtccggccgg gcgtcgcagt
    13861 ccgacgccac ctcacgcacc agcagtcggg cacactcgat ctccgtggcg agatccgcca
    13921 cgcggtgccg cagcgcctgg aaggagccga cgggtcggcc gaactgttcg cgctcgcgta
    13981 tgtaggcgac cgcgtcgtcg aaggcgcggc ggcccagccc cagcatgttg gccgccagga
    14041 agagccgctc gtggttgagc cccgccatca actggcgcca gccggagccg acttcaccga
    14101 ccaccgcgtc cgggggaagc cgtacgccgg tgaggaacac gtcgttgacc tcgcggccgc
    14161 ccatggtctc gatgccccgc acctccactc ccggcgtgtt catcgggacg tggaacatcg
    14221 tgagcccctc gtgccggtcc ccgcccgtcc gtgccaccag caacatgctc tcggccacat
    14281 gggcgttcga gatccaggtc ttctgaccct cgacgagcca actcccgtcg ggctgccgct
    14341 cggcacggca gcgcagggcg gccacgtccg aaccggcgcc gggctccgac atggcgacgg
    14401 ccagcacctg accacgcgcc gcgccgccga gcaccgcacg gcgctgctcc tcggtgccga
    14461 aacgctcgta caccttggcg gtgatcacgg tggtgacgaa gccgccggcg ggcaccagtc
    14521 cgtaggaggt ctcctccagg aagacgcagg cgtcggcgag gccgccgccc gcgccgccgt
    14581 actcctcggg caggcatact ccgagccagc cgaggtcggc gagcatggcg tagatcttgg
    14641 gattgtgggg ctcccggccg ccctgggtga gcgcgtcccg ctgcacggga cttccgcact
    14701 cgcgctgggc gaattcacgt acggcggcgg cgaaatcgga ctgctgcggg gtgaggcgac
    14761 tgcccatggg tcctccgaag acgagggaac ggcgtggtgg gacaacaagt gagatacaga
    14821 tatatggtta atgtttcact gtatctatga aaggggtgcg ggtaccgtga aaggcaccat
    14881 gaagacatct gcgaacgact ccctgctggc ccgggccatc gcccggccgg agacagagga
    14941 aaagctggcg cggcagatcc tcgacgccgc cctggagcag ttcacgacct tcggcctgcg
    15001 ccgctcctcg gtcgaggacg tcgccaaacg ggccggcgtc tcgcgcgtca cggtgtaccg
    15061 ccgtttccag agcaaggacg gactggtcga ggcgtgtctg ctgcgcgagg gcagccgctt
    15121 cttccaggag ctggactccg ccgtcgcctc gctgccgacg atggaggacc gggtcgtgga
    15181 gggcttcgtg gtcgccctgc ggcacaccag ggcccatccg ctgttcggcg gactgctgaa
    15241 gctcgaaccc gaggtggttc tgccgtactt caccgtccag ggcggcgcct ccctcgccgc
    15301 caccacggac tacctgaccg cccatctgcg gcgcgcccag cacaccgagg gccgcccgga
    15361 gaccgacccc cggccggtgg cggagctgat ggtgcgcgtc gcggtctcct tcctcctcaa
    15421 cccggccggc tgtatcgaac tgggcgacga ggagcaggcc cgcgcgttcg cccgcagata
    15481 cctcgcgccc ctgctcgacg cctgaccctg cgcccgccgt caacgccggg agtgcagcca
    15541 ccgcatgagc gccacggccc tggccttcgt cgcggcgggg gtcgcgaacg acgtcagatc
    15601 gaccggcggt gcgaagcgcc ggacggtcac cgactgcggg gtggtgaagg cccgcagtcc
    15661 gtccgcgccg tggatccggc cgaaaccgga gtcaccggac ccgccgaacg gcagggccgg
    15721 gacggcggcg aagcccagca ccgagtcgac ggagaccgcg cccgcccgca gccgggacgc
    15781 cagcgcggca ccggcgcgac ggctgccgcc gaacaccgcg gcgcccagcg cgtagcgtga
    15841 cgcgttcgcg cgccggaccg cctcatcctc gtccgccacg gcgttcaccg cgaccgtcgg
    15901 cccgaaggtc tcctcggtca tggcgggcga gtcctcgggt acgtcgacca ggaccaccgg
    15961 ctccacgaag gccccggccg ccggcgccga ttccgagccg ccgagcgccg cgcccgcccc
    16021 cgccgccagc gcatcctgga catgccgccg caccaccgcc gtctggtccg gcatcgtcat
    16081 aggaccgtag gccgcgtcag gaccggcgcc cgggcgcagg ccccgggccc gctcgaccac
    16141 cttctcgcac agcgccgcgt gcacctgccg tacggcgtag acgcgttcga cgcccgcgca
    16201 ggtctgcccg gcgttgccca tcgcacccca cacgatcgcg tcggccgcgg catccagatc
    16261 cgcgcccgcc gtcacgatga ccgcgtcctt gcccccgcac tccgccagga acggcgtgag
    16321 cgattcggcg cacaccgcca tcaccttgcg cgcggtcccc ggggacccgg tgaaggcgac
    16381 cttgtcgact ccggagcggg ccagcgcccc accggtcgcc gcggccccgg tgacgacggt
    16441 gaacagtccg gcgtacccgg gcacggccgc gtcgaacagc tcggcgagca gcacccctgt
    16501 accgggggtg tactcggagg gcttgaagac cacggcgtta ccggccgcca gggcgtagcc
    16561 gatggatccc atcggcgtgt acacggggta gttccagggg ccgatcaccc cgacgacgcc
    16621 gagcggacgg cggaccacgg tcgccgcctg gtgcatcgcc accgccccgg agcgcaccct
    16681 gcgccggcgc agcacgcgcc cggcgttgcg ggccgcccac gacaagtgct ccagggtgag
    16741 caggagttcc agttcggcgt cctggcgggg tttgccggtc tccgccgcga cgatccccgc
    16801 cacggtgtcc agggacgacg ccaactcccg cttccagcgc agcagatgtc cgcgccgctt
    16861 accggcggac agggccgccc agcgggtccc ggccgcccgc gcccgccgca cggcacggtc
    16921 gacgtccagc ggcccgtgga cggggtacgc ggcgagggcc tcaccggtga cgggggagcg
    16981 ggaggtgaag ctgccgggcg gggaagtgcg tcgctcgacg gaatctgccc gcgtgccgtc
    17041 cgcggtggaa ccgggttcgg tgggtgcggc ggtgtcggtg gaaccgggtg ccgtgggtcc
    17101 ggacgtgtcc gtgggagccg gttccgtgag cccggaggtg tcggcggcgg cgggttccgt
    17161 gtgcccggcg ggaccggtgg tggcgggatc cggctgtccg gcggtgtcgg tggagcccgg
    17221 tcccgtggct ccgccgggtc ggtcggcgtt ctcggtggtg tgggtcatcg gcgctccatc
    17281 ggtgggttct cgtcggcgag cggggtcggt ggcctgtggt gggcccagtg cgggccgagg
    17341 tcgtcgagcg tccagccgaa ggggtagctg cggggtttgg gccggctcgg ccaccagccg
    17401 ggccgggcgg gcaagtggcg ggtcagcagg gcacgggtcc gcaggaggac gtgggccgcc
    17461 gtgcgtaccg ggcgcggctg cgggcggaag ccgagcgcgg tcagcagcgt ttcgtccagg
    17521 acggccaggg cgaggcgggc cacgagcggt cgcagtggcc gcgggtacca gtcggtgatg
    17581 atccgcaggg tggccgcggc gacccgccgg ttggcggggt cgtacgcgaa catctccttc
    17641 tcgtaggtgt cgtggagctg ttcgaacccg gcgtagtcgg cggggagatc ggtgatcccc
    17701 atcatctcgc ccatgcgccg accgaccagg gccagactct cggcctcctg cgggcacagc
    17761 ggccgccagc cgtaccggtc gatccaccgc ttgggtccga ccacggtcgt cgccaggacg
    17821 tacaggtagt cctcgttcgg tatgcggtaa cggccgtgga tgcggttgag gtgacgggcg
    17881 gtggcccggc cgtgcgggga gtccatgccg tggcggacca tctcgtacgc gatcagcacc
    17941 gtgtcgtcgt agcgcttctg tcccgcgcgc tcgaactcct gcgttcggtc gaggagttga
    18001 gagatgcggg gcacgccgta gtcgcgcagg aaggcgacgg acacaccctg catgtagtcc
    18061 caggggaact cgtaccgggt gatccaccgg aagatctcct cgtggtcgtg ccggggatcc
    18121 atccggcgga tccgttcgag ccggctgtag cggcccatgg gtgatgcctc ctatcggctg
    18181 tcgggctggc ggcctatcgg gctgtcgggc tatcgggtgt gactgtgcgc gctcaggccg
    18241 gagaagttga ccgtctcggc gtcgaccagc acctggccgg cctccaccgc cgtgaccgac
    18301 agctcgggca gctgaacggc gatcggcagg ttcgccggca cgacgtcggc gccgatgcag
    18361 atgcgcgggg tggcgacgtc gatgacgggg atggtgaggg agccggagag ccgggtgacg
    18421 tagatgtcga cctgcgggat gtcgaggtcc acgtcgatcg tctgcacctg gcccggcgtc
    18481 tccagacgga aggtgtagtc gtccgcgacg agccggtccg cgtgcaccca gagcaccttg
    18541 agctgcccgc cgccgaccgt cccgagatag gtggcgccgt ggacgatggc cccgtaggcg
    18601 gtcaggctgt ccgcaccgac ctggggatag acggtgttga ccgggtaggc cgcgcgggga
    18661 cggcccggct ggtccccgac gacgacgggc gggcgcaggg ccgtcaggtc gtcggggtcc
    18721 gcgggcatct cgcccggctc ggggttgggc agtccgccgg tgtcgacgcc ggtcaggcac
    18781 gggagggtga cctgggggcc caggacggct ccgggccggt ccgcgggccc ttcggtgccg
    18841 gctccgtcgt ccggaccgcc gccctggtcg gcgtcgcccc ccgacgagtc cggggccgag
    18901 tccgagcccg ccgaagggct cgcgttcggg cccgcggaag ggcccgtgga cgggccgggg
    18961 gtggcgccgg gggaggcgga tcccgtgggg gaggggccgg cctcggccgc cggggactcc
    19021 gacggagtcg cggacggcgc tgtggacgag gtgtcgcccg acccccactc ccatggccag
    19081 ccgttcgtcg gccagggcag cgggaacagg ccggtgccgg ggtgcgccgc ggcgccggtg
    19141 gcacccggga gcatcgcggc cgccagcgcc gtggtcagga cgaagaggac cgcgccccgc
    19201 gcaccggccc ggcgcccgcg gtaccgggct cggccctcat cggcttttgg gcggccgctc
    19261 gctccgtccc cggcggccgg ggcatcggcg gtccgctccg caccggctgt cgcgcccgta
    19321 gtccgctccg ctcgggctgc cgcgcccgcg ggctgcgcgg aggccggctg cgtggaggca
    19381 ggccgtgcgg aggcggggcc ttgaggcgtt tgcggttctc gggggccttc ctcggggtgc
    19441 cggttgcccg gcatccagcc gaaggccatg gaggagccga tgaggcccgc cagcatgccg
    19501 atgccgaaac cgcccaggtt cgtcgtcgcc atcgaggtca gggacgcgac ggccgtgacg
    19561 accgagacga acatgcgctg gtcgggcttg aagaggaaga agatcccgcc cgcgacgagg
    19621 accacggcga taccggcggc cgacatcgcg cccaccccga ccctgatcat cagtggcagc
    19681 ggggcgagcg ggatggcgac catctcgatt ccgcccgcga tcacccacac cgccgcccag
    19741 aacggacgtc tcctgcgcca ggcgcgcagc gagcggcgaa cccgccgcgc gggcaggacc
    19801 cggtcgatcc agtccccggt ctcccgggcc agctccgaca ggaagccgag aacgaaagcg
    19861 aacatgcccg aacccgtctc tcggcgccgt cagaagcact gcttgccgga acggctgaac
    19921 tcgatctcca gcttctccag cgtcagcgtg ccgccgttgg ccgagtaggc ggtgctccgc
    19981 aggtcatggg cgaccgcggt gtccgcctgc actccgaaca cgcccttcgg cccggtcacg
    20041 cccggcgcgc cggtcagggt ggacgcgtcc cggccggcct gtacaccggt gacctttccg
    20101 ccgcccccgg tgagcgcgtc ggcgttcacc acgaggttgg tgcccgcgag cggcttgtcc
    20161 gcgcccgagt gcaccagcat ggagatctct ccgaccagcg gaagcttctg cttgagcgag
    20221 acgcacacgt cggagacggt gccgtccttg acggccgcga gcaggaccgg cctggcgtcg
    20281 tcggccgagc cgccgatgga ggaggggaag gacgacacgc cctgcgcggt gacctccgag
    20341 gcggacacct tgaacgccgt gccggatacg gcgaacgagg cggcgatcgc cccttccgcg
    20401 agcgcgatgc ccagcgcgcc caccgccagg gtgcagggga cgaacatcag ggcgctgcgc
    20461 cgccagtgcg tccgaccctc gtccgcgttt ccgatatgtg catatctgtc cctcacggtg
    20521 ttttccttac ctttaggggt gaatgccggg atcccgcgtc ggggtgtcgt cgagagagtc
    20581 gaagatacaa a
//
