LOCUS       NZ_LMEQ01000012        21059 bp    DNA     linear   CON 07-JUN-2024
DEFINITION  Streptomyces sp. Root1310 contig_2, whole genome shotgun sequence.
ACCESSION   NZ_LMEQ01000012
VERSION     NZ_LMEQ01000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root1310
  ORGANISM  Streptomyces sp. Root1310
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1120187)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 1120187)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140604
            Assembly Name                     :: Root1310
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001426425.1-RS_2024_06_07
            Annotation Date                   :: 06/07/2024 02:14:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,470
            CDSs (total)                      :: 8,385
            Genes (coding)                    :: 8,123
            CDSs (with protein)               :: 8,123
            Genes (RNA)                       :: 85
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 262
            CDSs (without protein)            :: 262
            Pseudo Genes (ambiguous residues) :: 0 of 262
            Pseudo Genes (frameshifted)       :: 98 of 262
            Pseudo Genes (incomplete)         :: 219 of 262
            Pseudo Genes (internal stop)      :: 20 of 262
            Pseudo Genes (multiple problems)  :: 64 of 262
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:32:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 876850
            Orig. end                         :: 897909
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMEQ01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21059
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="3"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21059
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21059
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11059](+)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11059
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     misc_feature    6..20
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    complement(331..344)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.57"
                     /tool="antismash"
     misc_feature    414..428
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            complement(1565..1822)
                     /locus_tag="ASD48_RS22070"
                     /old_locus_tag="ASD48_13610"
     CDS             complement(1565..1822)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018563321.1"
                     /locus_tag="ASD48_RS22070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13610"
                     /product="WhiB family transcriptional regulator"
                     /protein_id="WP_016639615.1"
                     /transl_table=11
                     /translation="MDWRHNAVCREEDPELFFPIGNTGPALLQIEEAKAVCRRCPVMEQ
                     CLQWALESGQDSGVWGGLSEDERRAMKRRAARNRARQASA"
     misc_feature    1866..1881
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     misc_feature    complement(1867..1878)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     misc_feature    1931..1940
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.27"
                     /tool="antismash"
     misc_feature    2043..2052
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: medium, score: 15.86"
                     /tool="antismash"
     gene            complement(2142..3110)
                     /locus_tag="ASD48_RS22075"
                     /old_locus_tag="ASD48_13615"
     CDS             complement(2142..3110)
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006134762.1"
                     /locus_tag="ASD48_RS22075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13615"
                     /product="diacylglycerol kinase family protein"
                     /protein_id="WP_054242776.1"
                     /transl_table=11
                     /translation="MRALLVVNPAATTTSARTRDVLIHALASEMKLEAVTTEYRGHARD
                     LGRQAADSGNVDLVVALGGDGTVNEVVNGLLHAGPDPENLPGIAVVPGGSTNVFARALG
                     LPNDPVEATGALLDALREGGERTVGLGLAAGTPGTEDEAVPSRWFTFNAGLGFDAGVVG
                     RVEQQRERGRRSTHALYIRQAMRQLLGESQRRHGSITLERPGAEPVTDLVLSIVCNTAP
                     WTYLGNRPVYASPKASFDTGLDVLGLSRLSTASVARYGTQLLTSSPERGPHGKHAVSLH
                     DLDQFTLHSKVPLPLQMDGDHLGLRTSVTFTGVRRALRVIV"
     misc_feature    3247..3263
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 22.65"
                     /tool="antismash"
     gene            3260..3700
                     /locus_tag="ASD48_RS22080"
                     /old_locus_tag="ASD48_13620"
     CDS             3260..3700
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983568.1"
                     /locus_tag="ASD48_RS22080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13620"
                     /product="hypothetical protein"
                     /protein_id="WP_057603357.1"
                     /transl_table=11
                     /translation="MSSDETSAAPETTGPRPRRLTYAAALVALEGLALVVGGVCMLALG
                     ISGDPDDRQQAVTGGVTLIVLALLPLLAARGLLGLRSWSRGPAVITQVMALPVAYNLLQ
                     ADSLAIPAGIALAAVAVASLVLLVNGETTRALGIRGPGRASE"
     gene            complement(3740..4852)
                     /locus_tag="ASD48_RS22085"
                     /old_locus_tag="ASD48_13625"
     CDS             complement(3740..4852)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030133.1"
                     /locus_tag="ASD48_RS22085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13625"
                     /product="RNA polymerase sigma factor SigF"
                     /protein_id="WP_107104366.1"
                     /transl_table=11
                     /translation="MRNGDGPVRDEERGTRELPAENAEIPVSPDGSRRMADGIDGIPEQ
                     ARPHPEDESVSAQAGLPEGAVQGSPRERRIGGSPPGRAEARARQRATGGTMSEHQRDGE
                     QSVPGTQHEPPATPAPGDRSGARAMFIELRKLENTSAEYADLRNQLVRMHLPLVEHLAR
                     RFRNRGEPLDDLTQVATIGLIKSVDRFDPERGVEFSTYATPTVVGEIKRHFRDKGWAVR
                     VPRRLQELRLALTTATAELSQQHGRSPTVHELAEKLAISEEEVLEGLESANAYSTLSLD
                     VPDTDDESPAVADTLGAEDEALEGVEYRESLKPLLEDLPPREKRILLLRFFGNMTQSQI
                     AQEVGISQMHVSRLLARTLAQLREKLLVEE"
     gene            complement(4849..5262)
                     /locus_tag="ASD48_RS22090"
                     /old_locus_tag="ASD48_13630"
     CDS             complement(4849..5262)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003966375.1"
                     /locus_tag="ASD48_RS22090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13630"
                     /product="anti-sigma regulatory factor"
                     /protein_id="WP_020130755.1"
                     /transl_table=11
                     /translation="MSQIAGEPATQDFVEVRLPAAGAYLSVLRTATAGLAARLDFTLDE
                     IEDLRIAVDEACAILLQQAVPGSVLSCVFRLVDDSLEVTVSAPTTDGHAPSRDTFAWTV
                     LSALAGKVSSAVDEDKTVTISLYKQRGAGPGPA"
     misc_feature    5389..5402
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.16"
                     /tool="antismash"
     misc_feature    complement(5428..5442)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.9"
                     /tool="antismash"
     gene            complement(5545..5805)
                     /locus_tag="ASD48_RS22095"
                     /old_locus_tag="ASD48_13635"
     CDS             complement(5545..5805)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018571357.1"
                     /locus_tag="ASD48_RS22095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13635"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_057603359.1"
                     /transl_table=11
                     /translation="MKQCTHADALPHPEPVPLGETCPECLRDGTHPVQLRLCLTCGHVG
                     CCDSSPSRHATAHHKESGHPVMRTFEPGENWRWCFVDHVLV"
     gene            5866..7464
                     /locus_tag="ASD48_RS22100"
                     /old_locus_tag="ASD48_13640"
     CDS             5866..7464
                     /GO_function="GO:0015385 - sodium:proton antiporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006814 - sodium ion transport [Evidence
                     IEA]"
                     /GO_process="GO:0006885 - regulation of pH [Evidence IEA]"
                     /GO_process="GO:1902600 - proton transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019072182.1"
                     /locus_tag="ASD48_RS22100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13640"
                     /product="Na+/H+ antiporter"
                     /protein_id="WP_057603360.1"
                     /transl_table=11
                     /translation="MDVMPLLLLVAGSAAFAAAARRTPVPAPLLLVAVGLVVSYVPGVP
                     DYTLDPDVVLPLLLPPLLYTSASDSSYLDLRAQLRPVALLSVGYVLFATFAVGWAAYLI
                     VPGLPLTAALVLGAVVAPPDAVAATAVARRVGLPSRITTILQGESLLNDATAITAYKVA
                     LAVVVGEGASWAGGIEEFLVAAVGGTAVGLILMAPLHWLRTHLKEPLLQNTLSLLIPFV
                     AYAAAEQFHASGVIAVVVVALYLGHRAWEVDFATRLQEEAVWKMVAFVLESAVFALIGL
                     QLPVVLKGLGAYEGAEAAWYAVALFLVVVAARFLWVYPATFLPRLLSARIRAREENPTW
                     RGPIVIAWAGMRGVVSLAIAFSIPLTVDHGDAPFPHRNLILFLTFTTVIGTLVVQGLTL
                     PPLIRLLKFPEPDPQAATLAEANAQAQASRVAEERLDALLADERNALPPPLADRLRSVL
                     ERRRNAVWERLGQVNPVTGETVDDTYRRLSREMISAEREMFVRLRDGRYIDDEMLRTLL
                     RRLDLEEAAAFREAA"
     gene            complement(7486..8370)
                     /locus_tag="ASD48_RS22105"
                     /old_locus_tag="ASD48_13645"
     CDS             complement(7486..8370)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130752.1"
                     /locus_tag="ASD48_RS22105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13645"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_057603575.1"
                     /sec_met_domain="PALP (E-value: 9.9e-18, bitscore: 60.5,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLRPRLPSPLQEVSDERFGRYGVRLLLKRDDLIHPELIGNKWR
                     KLAPNLERAAGRTLLTFGGAYSNHLRATAAAGRLLGQPTVGVVRGDELAGRPLNPSLAR
                     CAADGMRLHFVDRSTYRRKAEPDVLGKLLDTVGARDAYVVPEGGSNAAAVRGCRALGEE
                     LRGRTDVVALACGTGGTLAGLAAGLAPGQRALGIPVLRGGFLGDGIQALQEEAFGGRRG
                     EWRLDERFHFGGYARVTPELEAFAADFEGRHAVPVERLYVAKSLYGLVALAEEGAFARG
                     TTVTAVITGRPFP"
     gene            8544..9950
                     /locus_tag="ASD48_RS22110"
                     /old_locus_tag="ASD48_13650"
     CDS             8544..9950
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136651.1"
                     /locus_tag="ASD48_RS22110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13650"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_057603361.1"
                     /transl_table=11
                     /translation="MSVGEEVRADSGKPQQSLGTAAARNLATTTKSAPQMQEISSRWLL
                     RNLPWVDVQGGTYRVNRRLTYAVGDGRITFVKTGDRVEVIPAELGELPALRSYEDEEVL
                     GELAQRCRQREFGPGEVIASFGSQSEEVYLLAHGRVEKVGTGPYGDDQVLGVLADGAYF
                     GDQALLDADAIWEYTARADTACTVLILARQDVEQVAERAESLREHLHQLRAIPEQRTNK
                     YGEKEVDLAAGHAGEPDIPHTFVDYDARPREYELSIAQTVLRIHSRVADLYNQPMNQTE
                     QQLRLTVEALKERQEHELVNNREFGLLHNCEYDQRLQPHDGVPSPDDLDELLSRRRGTK
                     MLLAHPRAISAIGRELNKRGLVPETIDVGGNRIPTWRGVPIYPCNKIPVTAARTSSIIA
                     LRLGQEDQGVIGLRQSGIPDEIEPSLSVRFMGINEQAIIKYLVTAYYSAAVLVPDALGV
                     LENVEIGRWR"
     gene            10001..11059
                     /locus_tag="ASD48_RS22115"
                     /old_locus_tag="ASD48_13655"
     CDS             10001..11059
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136650.1"
                     /locus_tag="ASD48_RS22115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13655"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     polyprenyl transferase"
                     /protein_id="WP_242432688.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2.7e-60, bitscore:
                     199.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSQGDSGPGPADGYDAAVILERSRASVDPELRRAIDALPRSMRR
                     VALYHFGWEHADGTPAAANAGKAIRPALVLAAATALGGPAARAAALRAAAAVELVHNFT
                     LLHDDVMDRDTTRRHRPTAWTVFGDADAILAGDALQALALGLLAVDPHPASAAAARRVA
                     ACVVELCAGQQADTALEKRGPAETTLDEVLVMAEAKTGALLGCACAVGALYAGAAEEDV
                     DALDAFGREAGLAFQLIDDVIGIWGDPRHTGKPAGADLAARKKSLPVVAALTSGTPAAA
                     ELAELYAAPYDPADLDRTTLAVERAGGREWAQEQAADRMARAMHELARAIPDPEAAGGL
                     LSLAEFVTRRSN"
     gene            complement(11257..11862)
                     /locus_tag="ASD48_RS22120"
                     /old_locus_tag="ASD48_13660"
     CDS             complement(11257..11862)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130749.1"
                     /locus_tag="ASD48_RS22120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13660"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_057603363.1"
                     /transl_table=11
                     /translation="MAGNPERRAALVDAGVEVLAREGARGLTFRAVDSAAAVPVGTASN
                     YFTGRDDLLRQIDARLHVRLAPDPEVLGALLARPRDRSLVTAFMHDLTARATRDRSGYL
                     ALLEMRLEATRRPELRASFTTSVRGDLDQGLFFHREAGLPGGDETVVVLYLAMLGLILE
                     HLTLPDVLDGVLPGVGVPEGLVERIVATVVPDGAGEPA"
     misc_feature    complement(11928..11944)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 17.62"
                     /tool="antismash"
     misc_feature    11931..11944
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.91"
                     /tool="antismash"
     gene            11984..12568
                     /locus_tag="ASD48_RS22125"
                     /old_locus_tag="ASD48_13665"
     CDS             11984..12568
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973718.1"
                     /locus_tag="ASD48_RS22125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13665"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_057603364.1"
                     /transl_table=11
                     /translation="MRKLTYFIACSVDGFIGDVNGDGSAMVSYVDEEFLDFLKAEYPET
                     VPTHGRRALGFDDLENKRFDTIIQGRASYDLALKEGVPSPYAHLRQYVASRTLGRSPSP
                     DVEIIADGLLDKVRELKAEDGGLGIYLCGGSRVAGELIDEIDELVIKTYPMVYGAGMPM
                     FGTGFDIARFTFGGVRSFGNGAVVRTYARER"
     gene            12626..12871
                     /locus_tag="ASD48_RS45005"
                     /old_locus_tag="ASD48_13670"
     CDS             12626..12871
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003998007.1"
                     /locus_tag="ASD48_RS45005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13670"
                     /product="hypothetical protein"
                     /protein_id="WP_063887477.1"
                     /transl_table=11
                     /translation="MDREQRVCPSCGQPVQSVVRRHKTLGAWVPRWVPGPCHNPHCEEY
                     VEPGPRHKAAEAAEAAGAEEEPAPETEPETPAAPTS"
     gene            12891..13469
                     /locus_tag="ASD48_RS22135"
                     /old_locus_tag="ASD48_13675"
     CDS             12891..13469
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014045238.1"
                     /locus_tag="ASD48_RS22135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13675"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_057603366.1"
                     /transl_table=11
                     /translation="MTSRVTLISPAVTSALREARFDDGSCEVDAAGMRRARSAAALLRG
                     ADRSAASPSTRCRQTAEALGLPAPEVPALAALDVGRWRGRTLTEVSAAEPDAVASWLAD
                     PARAPHGGETVLELCDRTGAWLEDTARTPGRVTAVVEPDVVRALLVRALGLPEPAFWRL
                     DVRPLTAVDLSGRAGRWNLRVGAPLGEGP"
     gene            complement(13482..14267)
                     /locus_tag="ASD48_RS22140"
                     /old_locus_tag="ASD48_13680"
     CDS             complement(13482..14267)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130745.1"
                     /locus_tag="ASD48_RS22140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13680"
                     /product="VOC family protein"
                     /protein_id="WP_057603367.1"
                     /transl_table=11
                     /translation="MSGPVRWAHVFVDRPTRSFARACDFWTAVTNTSLSAPRGGDGEFV
                     TLLPKDVGADACVKAQAVTDGEGGAHLDLSVRDVPGFVAAARELGAETAAAHDGWAVLR
                     SPAGQLFCAVPWHGESVRPPVVAGSRLDQVCMDVPPSAYESEVAFWSGLLPDWSARPGS
                     RPEFHVVEPPPGLPVRVLLQRLDTEGAVRAHPDLACGPDIDAVRARHEELGAVLVARRS
                     HWTVMRDPTGGLYCLTGRDAETGGLPRAASRATGPTSGH"
     gene            complement(14264..14677)
                     /locus_tag="ASD48_RS22145"
                     /old_locus_tag="ASD48_13685"
     CDS             complement(14264..14677)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016437940.1"
                     /locus_tag="ASD48_RS22145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13685"
                     /product="VOC family protein"
                     /protein_id="WP_057603368.1"
                     /transl_table=11
                     /translation="MDLKLHQCFVAVDDHDKALHFYVEVLGLEVRNDVSFEGMRWVTVG
                     SPLQPDVNLVLEPPGANPDFSSADREAMARLLAKGVLRGVIFTTADCDALHARVLEAGV
                     EVLQEPTDQPYGVRDCAFRDPAGNMLRFMERAG"
     gene            complement(14688..15089)
                     /locus_tag="ASD48_RS22150"
                     /old_locus_tag="ASD48_13690"
     CDS             complement(14688..15089)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130743.1"
                     /locus_tag="ASD48_RS22150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13690"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_107104367.1"
                     /transl_table=11
                     /translation="MTLEDLKRLRQARDRMDREYAEPLDVAVLASTALMSPGHFQRSFR
                     EAYGETPYGYLMTRRVERAKTLLRRGDLTVTEVCMAVGCTSLGSFSSRFTELVGETPSA
                     YRARSHEAGAVIPSCVVRTYTRPLRGRHT"
     gene            complement(15332..15727)
                     /gene="sodN"
                     /locus_tag="ASD48_RS22155"
                     /old_locus_tag="ASD48_13695"
     CDS             complement(15332..15727)
                     /EC_number="1.15.1.1"
                     /GO_function="GO:0004784 - superoxide dismutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009313646.1"
                     /locus_tag="ASD48_RS22155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13695"
                     /product="superoxide dismutase, Ni"
                     /protein_id="WP_020130742.1"
                     /transl_table=11
                     /translation="MLSRLFAPKVKVSAHCDLPCGVYDPAQARIEAESVKAVQEKMAAN
                     DDPHFQARATVIKEQRAELAKHHVSVLWSDYFKPPHFEKYPQLHQLVNDTLKALSAAKA
                     STDPKTGEKALELIAEIDKIFWETKKA"
     gene            15873..16307
                     /gene="sodX"
                     /locus_tag="ASD48_RS22160"
                     /old_locus_tag="ASD48_13700"
     CDS             15873..16307
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016485 - protein processing [Evidence
                     IEA]"
                     /GO_process="GO:0019430 - removal of superoxide radicals
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sodX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004925778.1"
                     /locus_tag="ASD48_RS22160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13700"
                     /product="nickel-type superoxide dismutase maturation
                     protease"
                     /protein_id="WP_057603577.1"
                     /transl_table=11
                     /translation="MPELSQETERARAAALFGLAEVTGPSMVPTLYQGDRLVVQYGARI
                     RVGDVIVLRHPFQQDLLVVKRAAERREGGWWVRGDNTYAGGDSTDYGTVPDELILGRVR
                     LRYRPPKPGQRSPLAVLRWALSAARPVPAVRSASRRLRAR"
     gene            complement(16211..16840)
                     /locus_tag="ASD48_RS22165"
                     /old_locus_tag="ASD48_13705"
     CDS             complement(16211..16840)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326935.1"
                     /locus_tag="ASD48_RS22165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13705"
                     /product="CGNR zinc finger domain-containing protein"
                     /protein_id="WP_057603369.1"
                     /transl_table=11
                     /translation="MELAYYSDYAVRLVNSEEPARGKDALTSVEAVRALFGGNQSAGRR
                     ATEADVTRFRAVRARLRAVFEAADGGDETLAVDLLNSLLLEFPVSPQISGHDFRDDDGR
                     PLWHMHLADHPSNATAGYAAIAAMGLAFHLTEYGVDRLGLCEAGPCRNAYLDTSTNRSR
                     RYCSDRCATRANVAAYRARKRLEADRTAGTGLAADSAQRSTASGER"
     gene            16975..17772
                     /locus_tag="ASD48_RS22170"
                     /old_locus_tag="ASD48_13710"
     CDS             16975..17772
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030136.1"
                     /locus_tag="ASD48_RS22170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13710"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_057603578.1"
                     /transl_table=11
                     /translation="MDGVTTGVTTGSATGVTTGADWAAWQRSWDRQQEWYMPDREERFR
                     IMLDMVEGLVGPAPRVLDLACGTGTITARLLARLPGATSTGVDLDPALLAIAEGTFDGD
                     DRVTLVTADLKDPDWPARLPYDTYDAVLTATALHWLHSEPLAALYGQVAELVRDGGVFM
                     NADHMIDDTTPRINAAERAQRHTRMDQARADGVLDWAEWWQLAAEDPVLAGPTARRFEI
                     YGEHADGDMPSASWHARVLLEQGFSEARPVWASPSDTLLLALR"
     gene            complement(17905..18657)
                     /locus_tag="ASD48_RS22175"
                     /old_locus_tag="ASD48_13715"
     CDS             complement(17905..18657)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190578.1"
                     /locus_tag="ASD48_RS22175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13715"
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_057603579.1"
                     /transl_table=11
                     /translation="MVKAEGVHKSFGLVEVLKGIDLEVRSGEVFCLIGPSGSGKSTFLR
                     CINHLEKINAGRLYVDGELVGYRQKGDKLYELKDSEVALKRRDIGMVFQRFNLFPHMTA
                     LENVVEAPVQVKGASRAQAKERAMQLLERVGLADKAGGYPSQLSGGQQQRVAIARALAM
                     DPKLMLFDEPTSALDPELVGDVLDVMRDLAESGMTMVVVTHEMGFAREVGDSLVFMDGG
                     VVVESGNPRDVLTNPQHERTQSFLSKVL"
     gene            complement(18708..19646)
                     /locus_tag="ASD48_RS22180"
                     /old_locus_tag="ASD48_13720"
     CDS             complement(18708..19646)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983523.1"
                     /locus_tag="ASD48_RS22180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13720"
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_057603370.1"
                     /transl_table=11
                     /translation="MTVDIDKADGPADTPPAGPQAIKAIPVRHYGRYVSAVVALAVLAG
                     IVYAFAQGRINWGAIPDYFFNDRILSGVGKTLLLTVLCMLIGIVGGILLAVMRLSKNPV
                     TSSIAWFYIWFFRGTPVLVQLIVWFNLGLVFEYINLGPIYKNEWSDFMTPFLTALLGLG
                     LNEAAYMAEICRAGLLSVDEGQTEASHALGMSHAKTLRRIVVPQAMRVIVPPTGNEVIN
                     MLKTTSLVSVVQYSELLRVAQDIGQTSGAPAEMLFLAAAWYLVLTSIFSVGQYYLERYY
                     ARGSLRQLPPTPLQKIRANVLSFGRSKGGVA"
     gene            complement(19680..20642)
                     /locus_tag="ASD48_RS22185"
                     /old_locus_tag="ASD48_13725"
     CDS             complement(19680..20642)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973710.1"
                     /locus_tag="ASD48_RS22185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13725"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_057603371.1"
                     /transl_table=11
                     /translation="MTASSTRRTTAARTRLAAVGSLAVAGALLLTACGDQTKDSDSESS
                     GSASTSSAPLADKLPKAIRDAGVIKVGSDIAYAPVEFKDSAGKTVGIDPDIAAAMGKQL
                     GVTFKFENGTFDTLITGLRSNRYNIAMSAMTDTKDRQEGVDSDTGKKVGEGVDFLDYFT
                     AGVSIYTKKGDDQGIKTWSDLCGKKIVVQRGTVSEDLAKSEAKKCTGGKTIAIESFDND
                     QQAQTRLRGGGADAGSSDFPVAAYAVKTSGGGNDFQLVGEQVEAAPYGIAVAKDQTELR
                     DALKAALDAIIANGEYEKIITKWGVADGAVKEATINGGK"
     misc_feature    complement(21000..21013)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.35"
                     /tool="antismash"
     misc_feature    complement(21043..21053)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
ORIGIN
        1 caggacgaca tggtcggcca cctcgtcccg cgcggccgcc gtccgctgct cgacgccgcc
       61 ctggacgagg gccggatcgt gcgcgagggc gacccggaat ggcgtgagga ggtccccgta
      121 cgggtcgagt cgatccccgt acggcgtgag ggccgcgtcc tcggggtcat cgcccgcaac
      181 accaacctgc tcaccgtgcg cacccccagc cgcctggagc tcacctacct ccagagcgcc
      241 tccgacctcg cgcagatgat cgcggccggc tccttcccgt tccccaacca gcagatggac
      301 atggacgccg ccccgcgcgt cggcgacggc ctgatccgcg tcgacggcga cggaatcgtc
      361 cagtacgcct ccccgaacgc gctgtcggcc taccaccgca tgggcctcgc ctccgacctg
      421 gtcggccagc acctcggcct gaccaccgcc gaactcgccc ccacccgggg tccggtggac
      481 gaggccctcg ccaaggtcgc cagcggctgg gcgccccgcg agttcgagat cgaggccaag
      541 gacggggtca tccagttccg ggcgatcccg ctcaagccca agggcacccg catcggcgcg
      601 ctcgtgctgc tccgcgacgt caccgaactg cgccgtcgcg agcgcgagtt gatcaccaag
      661 gacgcgacca tccgggagat ccaccaccgg gtgaagaaca acctccagac ggtggcggcc
      721 ctgctgcgcc tccaggcgcg gcgtatcgag tccgagcgcg gccgggaggc gctggaggag
      781 gcggtccgcc gggtcggctc gatcgccatc gtgcatgaga cgctgtctca gaacctggac
      841 gagcgggtgg agttcgacga gatcgccgac cgggtactgg cgatggtcgc cgagatctcg
      901 cctggcaagg tcgccggccg ccgcagcgga cgcttcggca tcctggacgc cgaggtcgcc
      961 accccgctgt ccatggtcct caccgagatc ctgcagaacg ccctggagca cggcttcgtc
     1021 gagggcgaca ccggcacggt cgaggtgtcc gcggtccgcg gcggcaccac gaaggagacg
     1081 cggctcctgg tcaccgtcca ggacgacggc gtcgggctgc ccgagggctt cgacccgcac
     1141 acctccggca acctcggcct ccagatcgta cggacgctgg tggagggcga gttgggcgga
     1201 accttcgaca tggtcccggg gccggagcgc ggcacccagg tgatcctgga catcccggtg
     1261 cgcacacaga aatagcggac gcgcgtcggc gctttcgggc ggcgcggtca ggtgagggcg
     1321 cgcccgcagg cacggtccgg cggggcggtc aggtgagggc gcgggtggac ggtacgggca
     1381 gaacgcgcgg gcgggcccgg tgtgcgcgca gcaagaagcc ccggaccgtt caggggtccg
     1441 gggctcgaat gctcgttgcc agcttgtgct gcgcatcggg ggtactgcgc gctgcggctc
     1501 gggggcggga agatgcgtac tcgctgtacg cgccgccaag ctcaggcttg cggggcgggt
     1561 gttgtcaggc ggaagcctga cgggcccggt tgcgggcggc gcggcgcttc atcgcacgac
     1621 gctcgtcctc gctgaggcca ccccagacgc cggagtcctg gccggactcg agcgcccact
     1681 gcagacactg ctccataacc gggcagcgac ggcagacggc cttggcttcc tcgatctgca
     1741 gcagcgcagg accggtgttg ccgatgggga agaagagctc ggggtcttcc tcgcggcaaa
     1801 cggcgttgtg acgccagtcc atggctgcta cctctccttg gtattacgtg caagttgctt
     1861 gtgaatgtga acgctttcac gaatccctca acaagtgaag ggccaccagc caggttccct
     1921 ggcgcggtcc tgttgtttga agaggggttc cggtgatcag tggatgccgg tgttgcgggc
     1981 tgtcccgatc gccacgtaga gactcgcaaa cctcagcggc ggatacaacc ccttccggaa
     2041 agtttttttt gattcctcgg tgtcgactag gtcacagccg tacttccatg gggtggaccc
     2101 tggcctaaac gttcgagtga aaggacttca gccctttctg ctcacacaat cacacgcagt
     2161 gcacggcgta cgcctgtgaa cgtcacgctt gttcgcagcc ccaggtggtc accgtccatc
     2221 tgaaggggca aagggacctt cgaatgcaag gtgaactggt ccagatcgtg cagggagacg
     2281 gcgtgcttgc cgtgcgggcc ccgttcgggg gacgaagtga gcaactgggt gccatatcgg
     2341 gcgacagagg ccgtggacag acggctgaga cccagtacgt cgaggcctgt atcgaacgag
     2401 gccttaggcg acgcgtacac cgggcgattg cccagatacg tccacggagc cgtgttgcag
     2461 actatggaca gcaccaaatc ggtcaccggt tcggcacccg gacgctccag ggtgatcgac
     2521 ccgtgccggc gctgtgactc acccaacaac tggcgcatgg cctggcggat gtaaagagcg
     2581 tgggtggatc tcctgccgcg ctcgcgctgc tgctccaccc gccccaccac tccggcgtcg
     2641 aagcccagtc ccgcgttgaa cgtgaaccag cgcgagggca ccgcctcgtc ctccgtgccc
     2701 ggcgtacccg ccgcgaggcc gagcccgacc gtacgctcac cgccctcgcg cagggcgtcc
     2761 agcagcgcgc cggtggcctc caccggatcg ttgggcagcc ccagggcgcg ggcgaagacg
     2821 ttggtggaac cgccggggac caccgctata ccgggcaggt tctccggatc ggggccggcg
     2881 tgcaggaggc cgttgaccac ctcgttgacc gtgccgtcgc cgccgagggc caccaccaga
     2941 tcgacgtttc cgctgtccgc cgcctgccgg cccaggtcac gcgcgtgtcc gcggtactcg
     3001 gtggtgaccg cctcgagctt catctcgctc gcgagcgcgt ggatgaggac gtcgcgcgtc
     3061 cgtgcactgg tagtggttgc cgccggattg accacgagaa gtgcacgcat gagttgcagc
     3121 gtacctactg ggtggtaccg ggcacaggcc gaggtgggga tcgggtaaga gatcgcggag
     3181 tgagcctcga cacgagcgcc gcccccctcg cgcgcgggtg gcccggggcc cgcccgcagg
     3241 tgcgggatac ccttctgggg tgagcagtga cgagacctcc gccgccccgg aaaccaccgg
     3301 accccgcccg cgccggctga cgtacgccgc cgcgctcgtc gccctggaag ggctggcgct
     3361 ggtcgtcggt ggggtgtgca tgctcgccct ggggatcagc ggcgacccgg acgaccgtca
     3421 gcaggccgtc accggcgggg tcacgctgat cgtgctggcg ctgctgccgc tgctcgccgc
     3481 ccgtgggctg ctggggctgc gcagctggag ccggggaccc gccgtcatca cccaggtcat
     3541 ggcgctgccg gtggcctaca acctcttgca ggccgacagt ctggccatcc cggcgggcat
     3601 cgcgctcgcc gccgtcgccg tcgcctcgct cgtcctgctc gtcaacggcg agacgacccg
     3661 ggccctcggg atccgggggc cgggccgcgc atcggagtag gccgttcccg ctgccgctcc
     3721 gcttgtgccg cttgaaccgc tattcctcga cgagcagttt ctcccgcagc tgggccagcg
     3781 tgcgggccag caggcgcgag acgtgcatct gcgagatgcc gacctcctgc gcgatctgcg
     3841 actgggtcat gttgccgaag aagcgcagca gcaggatccg cttctcgcgc ggtggcaggt
     3901 cctccaggag cggcttgagg gactcccggt actcgacgcc ctccaatgcc tcgtcctcgg
     3961 cgccgagggt gtccgcgacc gccggtgact cgtcgtcggt gtcgggcacg tccagggaga
     4021 gggtggagta cgcgttggcg gactccaggc cctccaggac ctcctcctcc gagatcgcca
     4081 gcttctcggc gagctcgtgg accgtggggg agcggccgtg ctgctgcgac agctcggccg
     4141 tcgccgtggt cagcgccagg cgcagctcct ggagccggcg cggcacccgc accgcccagc
     4201 ccttgtcacg gaagtggcgc ttgatctcgc cgacgaccgt gggggtcgcg tacgtggaga
     4261 actccacgcc gcgctcgggg tcgaagcggt cgaccgactt gatcaggccg atggtggcga
     4321 cctgggtgag gtcgtccagc ggctcgccgc ggttgcggaa gcgccgcgcg aggtgctcga
     4381 cgagcggcag atgcatgcgg accagctggt tgcgcaggtc cgcgtactcg gcactggtgt
     4441 tctcgagctt gcgcagctcg atgaacatcg cccgtgctcc gctgcggtcc cccggggcgg
     4501 gggtggccgg tggttcgtgc tgcgtgcccg gcacgctctg ttcgccgtct cgctggtgct
     4561 cgctcattgt cccgcccgtc gccctctgtc gagccctcgc ctctgctcgg cccgggggcg
     4621 agcccccgat ccgcctctcc cgaggcgagc cctgcacggc accttccggc aggcccgcct
     4681 gcgcggagac cgactcgtcc tccggatgcg gccgggcctg ctcgggaatg ccgtcgatgc
     4741 cgtccgccat gcgtcgggaa ccgtccggag agactggaat ctcggcgttc tcggccggca
     4801 gctcccgtgt gccgcgctct tcgtcccgca ccggcccgtc cccgttcctc acgccggccc
     4861 gggtcccgcg ccgcgttgtt tgtagagact gatcgtcacg gtcttgtcct cgtcgacggc
     4921 ggaggacacc ttgcccgcga gggcggacag gacggtccag gcgaaggtgt cccgtgaggg
     4981 ggcgtgtccg tccgtggtcg gcgcggagac ggtgacctcc agcgagtcgt cgacgagtcg
     5041 gaacacgcaa ctgagtaccg agccgggcac ggcctgctgg agcaggatcg cgcaagcctc
     5101 gtccaccgcg atgcgcaggt cctcgatctc gtccagggtg aagtccaaac gggccgcgag
     5161 gccggccgtg gccgtccgca gcaccgacag gtaggcaccc gcagccggca gccggacttc
     5221 cacgaagtcc tgggtcgcgg gctcgcctgc gatctgggac accctcacct ccaaggtggt
     5281 acaagctttt cggggccgag ggtcgccccc cggggtaacg cgtgtgtggt gcagcggtga
     5341 cgctatcgcg ctctcaagtt tctgtccccg ggaccccaac cccctggcgt cactcacagt
     5401 aaagctgtga acacgctccg tgtctagagg gtcggtcggc ccaaatggga acagggcgcg
     5461 ccgggttgac gtacccaggc gtcagatggt cgaaccgtac ccgccggacg gccggggcgt
     5521 catggtctcc tcatagggct ctcctcatac gaggacatgg tcgacgaagc accagcgcca
     5581 gttctcgccg ggttcgaagg tccgcatcac cgggtgaccc gactccttgt ggtgtgccgt
     5641 cgcgtgccgg ctcggcgagg aatcgcagca gccgacgtgg ccgcaggtca ggcacagccg
     5701 aagttgcacc gggtgggtgc cgtcccgcag gcactccgga cacgtctcgc cgagcgggac
     5761 gggttccggg tggggcagcg cgtcggcgtg cgtgcactgt ttcatgattg ccagattacg
     5821 acgggcgtgc ggacgaccgc gcggaaaaac gagggcgggc tggacatgga cgtgatgcca
     5881 ctgctgttgc tggtggccgg cagtgcggct ttcgcggcgg cggcccggcg taccccggtg
     5941 cccgcgccgc tgctgctggt ggcggtcggc ctggtggtgt cctacgtgcc gggggtgccc
     6001 gactacaccc tggaccccga cgtcgtgctg ccgctcctgc tgcctccgct gctgtacacg
     6061 tcggccagcg acagctccta tctcgacctg cgcgcccagc tgaggccggt ggccctgctg
     6121 tcggtcgggt acgtgctctt cgcgaccttc gccgtcggct gggcggccta tctgatcgtc
     6181 cccgggctgc cgctgacggc ggcgctggtg ctgggcgcgg tggtggcgcc gccggacgcg
     6241 gtcgcggcca cggcggtggc ccggcgggtc ggcctgccgt cgcggatcac cacgatcctc
     6301 cagggcgagt cgctgctgaa cgacgccacc gcgatcaccg cctacaaggt ggccctcgcg
     6361 gtcgtggtcg gcgagggcgc gtcctgggcc ggcggtatcg aggagttcct ggtggcggcg
     6421 gtcggcggaa ccgccgtcgg cctgatcctg atggccccgc tgcactggct gcgcacccat
     6481 ctcaaggaac ccctgctcca gaacacgctc tccctgctga tccccttcgt cgcctacgcg
     6541 gcggccgagc agttccacgc ctccggcgtc atcgcggtgg tcgtcgtcgc gctctacctg
     6601 ggccaccgcg cgtgggaggt cgacttcgcg acccgcctcc aggaggaggc cgtgtggaag
     6661 atggtcgcct tcgtcctgga gtcggcggtc ttcgcgctga tcggcctcca gctcccggtc
     6721 gtcctgaagg gtctcggcgc gtacgagggt gccgaggccg cctggtacgc cgtcgccctg
     6781 ttcctcgtgg tcgtggcggc gcgcttcctg tgggtgtacc cggcgacctt cctgccccgg
     6841 ctgctgtcgg cgcgtatccg cgcgcgggag gagaacccga cctggcgggg gccgatcgtc
     6901 atcgcctggg ccggcatgcg gggcgtggtc tcgctggcca tcgccttctc catcccgctc
     6961 accgtggacc acggcgacgc gcccttcccg caccgcaatc tgatcctctt cctcaccttc
     7021 acgacggtca tcggcaccct ggtggtgcag gggctgaccc tgccgccgct gatccgtctg
     7081 ctgaagttcc ccgagcccga cccgcaggcc gcgacgctcg ccgaggccaa tgcccaggcc
     7141 caggcctccc gggtcgccga ggagcgcctg gacgcgctgc tcgccgacga gcgcaacgca
     7201 ctgccgccgc cgctcgccga ccggctgcgc agcgtcctgg agcggcgccg caacgccgtc
     7261 tgggagcgcc tcgggcaggt caacccggtc accggcgaga ccgtcgacga cacctaccgg
     7321 cgtctctcgc gcgagatgat cagcgccgag cgcgagatgt tcgtccggct gcgggacggc
     7381 cgctacatcg acgacgagat gctgcgcacg ctgctgcgcc ggctggacct ggaggaggcg
     7441 gcggcgttcc gggaggcggc gtaggcgcgg tcgtccgccg tcgcctcacg ggaacgggcg
     7501 gcccgtgatc acggccgtga cggtcgtccc gcgcgcgaag gcgccctctt cggccagggc
     7561 gacaaggccg tagagcgact tggcgacata gagacgttcc accggcactg cgtggcgtcc
     7621 ttcgaagtcc gccgcgaagg cctccagctc gggggtgaca cgggcgtagc cgccgaagtg
     7681 gaagcgttcg tcgagccgcc actcgccccg tcggccgccg aacgcctcct cctgcagcgc
     7741 ctgtatcccg tcacccagga agccgcccct gaggaccggt atgcccaggg cccgctggcc
     7801 cggggcgagg cctgccgcca ggccggcgag ggtcccgccg gtgccgcagg cgagggcgac
     7861 gacgtcggtg cggccccgca gctcctcgcc gagcgcccgg cagccgcgga ccgccgccgc
     7921 gttgctgccg ccctcgggca cgacgtacgc gtcccgcgcg ccgaccgtgt ccagcagctt
     7981 cccgagcacg tccggctcgg ccttgcggcg gtaggtcgag cgatccacga aatgcaggcg
     8041 catgccgtcg gccgcgcacc gggccaggga cgggttcagc ggccggccgg ccagttcgtc
     8101 gccgcgcacc acacccaccg tcggctgccc cagcagacgg ccggcggcgg ccgtggcccg
     8161 cagatggttg gagtaggcgc ccccgaaggt gaggagcgtc cgtcccgccg cccgctccag
     8221 attgggcgcg agcttgcgcc acttgttgcc gatcagctcg gggtggatca ggtcgtcccg
     8281 cttcagcagc agccggacgc cgtaccgccc gaaccgctcg tcggacactt cctggagggg
     8341 ggacggcagg cgggggcgga ggtcggtcac ccgctcattg tcgaacaccg ttcggtgaaa
     8401 cgtacctctt ccctgcccac gttgatccat tcccgctctt tcgggtaata gcacgagcac
     8461 acaccgtgat ggaaggcttg ccgcgtgaac gaagtgcatc ggcgcagttc ggcgtccgtg
     8521 catgaatcgg gagggcattt ctcatgtcgg taggcgaaga ggtccgcgcg gattcgggca
     8581 agccgcagca gagtctcggc accgcggccg cgcggaacct ggccaccacg accaagtccg
     8641 caccgcagat gcaggagatc agttcccgct ggctgctgcg gaatctgccc tgggtggacg
     8701 tgcagggcgg tacgtaccgg gtcaacaggc gtctgacgta cgcggtgggc gacggccgca
     8761 tcacgttcgt gaagaccggc gaccgcgtcg aggtcatccc ggccgagctg ggcgaactgc
     8821 ccgcgctgcg ctcctacgag gacgaggagg tgctcgggga actcgcccag cgctgcaggc
     8881 agcgggagtt cggcccgggc gaggtcatcg cctccttcgg cagccagagc gaagaggtct
     8941 acctgctggc gcacggccgt gtcgagaagg tcggcaccgg cccgtacggc gacgaccagg
     9001 tgctcggggt gctcgcggac ggcgcgtact tcggcgacca ggcgctgctc gacgcggacg
     9061 ccatctggga gtacacggcc cgggcggaca cggcctgcac ggtgctgatc ctggcccggc
     9121 aggacgtcga gcaggtcgcg gagcgtgccg aatccctccg cgagcacctc caccagctgc
     9181 gcgcgatccc cgagcagcgc accaacaagt acggcgagaa ggaggtcgac ctcgccgccg
     9241 gtcacgccgg cgagccggac atcccgcaca cgttcgtgga ctacgacgcc cggccgcgcg
     9301 agtacgaact gagcatcgcc cagaccgtcc tgcgcatcca ctcgcgtgtg gccgacctgt
     9361 acaaccagcc gatgaaccag accgagcagc agctgcggct gacggtcgag gcgctcaagg
     9421 agcgccagga gcacgagctc gtcaacaacc gcgagttcgg gctgctgcac aactgcgagt
     9481 acgaccagcg gctccagccg cacgacggcg tgccgagccc ggacgacctc gacgaactgc
     9541 tcagcaggcg gcgcggcacc aagatgctgc tcgcccaccc gcgcgcgatc tccgcgatcg
     9601 gccgtgagct caacaagcgc gggctcgtcc ccgagacgat cgacgtcggc ggcaaccgga
     9661 tcccgacctg gcgcggggtg ccgatctacc cgtgcaacaa gatcccggtg accgcggccc
     9721 gcaccagctc catcatcgcg ctgcgtctgg gccaggagga ccagggcgtc atcggcctgc
     9781 gccagtccgg catcccggac gagatcgagc cgagcctgtc cgtgcggttc atgggcatca
     9841 acgaacaggc catcatcaag tacctggtca cggcctacta ctcggccgcg gtcctggtgc
     9901 cggacgcgct gggcgtcctg gagaacgtcg agatcggccg ctggcggtga cttccgccac
     9961 caggcggtac cggggtgagg cgcgcgaaag gcggaggccc atcggcagcc agggcgacag
    10021 tggtccgggg ccggccgacg ggtacgacgc ggcggtgatc ctggagcggt cccgggcgtc
    10081 ggtcgacccc gaactgcgac gggccatcga cgcgttgcca cgctccatgc gccgggtcgc
    10141 gctctaccac ttcggctggg agcacgcgga cggcaccccg gcggcggcca acgcgggcaa
    10201 ggcgatccgc ccggccctcg tgctcgccgc ggccaccgcg ctcggtggcc cggcggcccg
    10261 cgcggcggcc ctgcgggcgg cggccgcggt cgaactggtc cacaacttca cgctgttgca
    10321 cgacgacgtg atggaccggg acaccacccg ccggcaccgc cccaccgcct ggaccgtgtt
    10381 cggcgacgcc gacgcgatcc tcgccgggga cgccctccag gccctcgccc tcgggctgct
    10441 ggccgtggat ccgcatcccg cgtccgcggc ggccgcccgc cgggtcgcgg cctgtgtggt
    10501 cgaactctgc gccggccagc aggcggacac ggccctggag aagcgcggcc ccgccgagac
    10561 caccctcgac gaggtgctcg tcatggccga ggccaagacg ggagccctgc tcggctgcgc
    10621 ctgtgccgtg ggcgcgctgt acgcgggggc ggccgaggag gacgtggacg cgctggacgc
    10681 cttcggccgc gaggccgggc tcgccttcca gctcatcgac gacgtcatcg gcatatgggg
    10741 agacccgcgg cacaccggca agccggccgg cgcggatctc gccgcacgca agaagtccct
    10801 gccggtggtc gccgcactga cctccgggac cccggcggcc gccgaactgg ccgagctgta
    10861 cgcggcgccc tacgacccgg ccgacctgga ccgcacgacg ctggccgtcg aacgggcagg
    10921 cggccgtgaa tgggcgcagg agcaggcggc cgaccgcatg gcccgcgcga tgcacgaact
    10981 ggcccgggcg atcccggacc cggaggcggc gggcggcctg ctgtccctgg cggagttcgt
    11041 gacccggcgc agcaactagg acccgacccg gcccgaccgg ccgaggccac gggccaacag
    11101 ggtcggagag gtacgcggag gggctgggag gagcgaggag ggtcgagaag gggcgaggac
    11161 gaggggggcg acggaggaag ccggactgtt ccggcgggtt ccggtccggc gggtcccgca
    11221 catccccacg gtgtgcgggg cccgccggcg tgcgtcctac gcgggttccc cggcgccgtc
    11281 cgggaccacc gtcgccacga tccgctcgac cagaccctcc ggcaccccca cccccggcag
    11341 gacgccgtcc aggacgtccg gcagggtcag gtgctccagg atcagcccga gcatcgccag
    11401 gtacaggacg acgacggtct cgtcgccgcc gggcaggccg gcctcgcgat ggaagaacag
    11461 gccttggtcg aggtcgccgc gcaccgacgt ggtgaaggag gcgcggagct cggggcgccg
    11521 ggtggcctcg aggcgcatct ccagcagggc gagatagccg ctccggtcac gggtcgcgcg
    11581 ggccgtcagg tcgtgcatga acgccgtgac cagggagcgg tcgcgcggcc gcgccagcag
    11641 cgcgccgagc acctcggggt cgggcgccag ccggacgtgc agccgggcgt cgatctgccg
    11701 cagcaggtcg tcgcggccgg tgaagtagtt ggaggcggtg cccaccggca ccgcggccgc
    11761 cgagtccacc gcgcggaacg tgagccctcg cgctccctcg cgcgcgagca cttccacccc
    11821 ggcgtccacc agggccgccc ggcgctccgg attcccggcc atgcggaacc ttctctctca
    11881 cttggctccg tttcccggaa gaccgggaaa ctcccttgca accactacag ttgaagtact
    11941 acaactggag tggtcggaaa gcagcctacg gaaagagccc cacttgcgaa agctcaccta
    12001 cttcatcgcg tgctccgtcg acggcttcat cggagacgtg aacggcgacg gctcggcgat
    12061 ggtctcctac gtcgacgagg agttcctcga cttcctcaag gcggagtacc cggagaccgt
    12121 gccgacccac ggccgtcgcg cgctcggctt cgacgacctg gagaacaaga ggttcgacac
    12181 gatcatccag ggccgggcca gctacgacct ggcgctcaaa gagggcgtcc ccagcccgta
    12241 cgcgcacctg cgccagtacg tcgcctcgcg caccctcggc cggtcgccct ccccggacgt
    12301 cgagatcatc gcggacggtc tgctcgacaa ggtccgtgag ctgaaagcgg aggacggcgg
    12361 cctcggcatc tacctgtgcg gcggctcccg tgtcgcgggc gagctgatcg acgagatcga
    12421 cgagctggtg atcaagacct acccgatggt ctacggcgcc ggcatgccga tgttcggcac
    12481 gggcttcgac atcgcccgct tcaccttcgg cggggtgcgc tccttcggca acggcgcggt
    12541 cgtacggacg tacgcaaggg aacgctgacc gacactgacg cacagcgggg agcgctcggg
    12601 tgcgtgccgc cctactctgg agggcatgga ccgggaacaa cgcgtctgtc cctcctgtgg
    12661 gcagccagtg cagtccgtcg tccggcgaca caagacgctg ggcgcgtggg tcccgcgctg
    12721 ggtgccgggc ccgtgtcaca accctcactg cgaggagtac gtggaaccgg gcccccggca
    12781 caaggcggcc gaggcggccg aggccgccgg ggccgaagag gaacccgcac ccgagacgga
    12841 acccgaaacc cccgccgccc cgacctcctg accccgccga gcggagaccg atgaccagcc
    12901 gagtgaccct gatctcaccg gcggtcacct cggctctgcg cgaggctcga ttcgacgacg
    12961 gcagctgcga ggtggacgcc gccgggatgc ggcgggcccg gtcggccgcg gcgctgctgc
    13021 gcggcgcgga ccgctcggcg gcctcgccct ccacccggtg ccggcagacc gccgaggcgc
    13081 tcggcctgcc cgcgcccgag gtacccgcgc tcgccgctct cgacgtcggc cgctggcgcg
    13141 gccggaccct caccgaggtg tcggccgccg agccggacgc ggtcgcctcc tggctggcgg
    13201 atccggcccg tgccccgcac ggcggggaga cggtgctgga gctgtgcgac cggaccgggg
    13261 cctggctgga ggacaccgcc cgcaccccgg ggcgggtgac cgccgtggtg gagcccgacg
    13321 tcgtgcgcgc cctgctggtc cgtgcgctgg gcctgccgga accggccttc tggcgcctcg
    13381 acgtacggcc gctgaccgcc gtggacctga gcggccgggc gggccggtgg aacctgcgcg
    13441 tgggcgcgcc gctgggagag gggccgtagg ccgctccgcg ctcagtggcc ggacgtcggt
    13501 ccggtggccc gggaagcggc tcgtggcagc ccgcccgtct ccgcgtcgcg ccccgtcagg
    13561 cagtacaggc cgccggtcgg gtcgcgcatc accgtccagt gggaccggcg ggccacgagg
    13621 accgcgccga gttcctcgtg ccgggcgcgt acggcgtcga tgtccgggcc gcaggccagg
    13681 tcgggatggg cgcggacggc gccctccgtg tcgagccgct ggagcaggac gcggaccggc
    13741 agccccggtg gcggctcgac cacgtggaac tccggccggg agcccggccg cgccgaccag
    13801 tcgggcaaca ggccgctcca gaaggccact tcgctctcgt acgccgacgg cgggacgtcc
    13861 atgcacacct ggtccaggcg gctgccggcc accacgggcg gccgcacgga ctccccgtgc
    13921 cacggcaccg cgcagaacaa ctgtccggcg ggggagcgca gtacggccca gccgtcgtgc
    13981 gcggcggccg tctccgcgcc cagttcccgc gccgccgcga cgaaaccggg cacatcccgc
    14041 acggagaggt ccagatgcgc gccgccctcg ccgtccgtga ccgcctgcgc cttcacgcag
    14101 gcgtcggcgc cgacgtcctt cggcagcagc gtgacgaact ccccgtcccc gcccctgggc
    14161 gcggagaggg aggtgttggt gacggccgtc cagaagtcgc acgcccgcgc gaagctccgg
    14221 gtgggccggt cgacgaagac gtgggcccag cggaccggtc cgctcatccg gcccgctcca
    14281 tgaaccgcag catgttgccc gccgggtcac ggaacgcgca gtcgcgcacc ccgtagggct
    14341 ggtccgtcgg ctcctggagc acctcgacgc cggcctccag cacccgcgcg tgcagggcgt
    14401 cgcagtcggc ggtggtgaag atgaccccgc gcagcacccc cttggcgagc agccgggcca
    14461 tcgcctcccg gtcggcggag gagaagtccg ggttcgcgcc cggcggctcc agaacgaggt
    14521 tcacgtccgg ctggagcggc gacccgacgg tcacccagcg catcccctcg aaggagacgt
    14581 cgttgcggac ttcgagaccg agaacctcga cgtagaagtg cagggccttg tcgtggtcgt
    14641 cgacggcgac gaaacactgg tggagtttga ggtccatggc gtccagccta ggtgtgcctg
    14701 ccgcgcagcg ggcgggtgta cgtccggacc acacaggacg ggatcaccgc gccggcctcg
    14761 tgcgaccgcg cccggtacgc gctcggggtc tcaccgacca gctcggtgaa gcgggagctg
    14821 aacgagccga gcgaggtgca gccgacggcc atgcagacct ccgtcacggt caggtcgccg
    14881 cgccgcagga gggtcttggc gcgctcgacc cgccgggtca tgaggtagcc gtagggcgtc
    14941 tcgccgtagg cctcgcggaa gctgcgctgg aagtggcccg gggacatcag cgcggtgctc
    15001 gcgagcaccg cgacatcgag tggctccgcg tactcacggt ccatccggtc acgtgcctgc
    15061 cgcagccgtt tcaggtcctc gagggtcacg gggccagcat cgcacggagg gcgccgtccg
    15121 ggcgggggat gtccgggaga gggaaatccg ggagaggggc gtccgggaga gggacgtccg
    15181 acagagggag ggaaaaggag accgcacccg ggccgtcggg ggcgccgtgt tcggcggccc
    15241 gcggaccggg tgcggacagg tgggcgggac gaccggcgcc ggtgcaggtc ggaccgcccg
    15301 aggcgaagat caggccctga tcgggatctg atcaggcctt cttggtctcc cagaagatct
    15361 tgtcgatctc ggcgatgagc tccagggcct tctcgccggt cttcgggtcc gtcgaggcct
    15421 tggcggccga cagggccttc agggtgtcgt tgaccagctg gtgcagctgg gggtacttct
    15481 cgaagtgcgg gggcttgaag tagtcgctcc acagcacgga gacgtggtgc ttcgcgagct
    15541 cggcacgctg ctccttgatg acggtggcgc gcgcctggaa gtgcgggtcg tcgttggcgg
    15601 ccatcttttc ctggacggcc ttcaccgact ccgcctcgat gcgggcctgg gccgggtcgt
    15661 acacaccgca gggcaggtcg cagtgtgcgc tgaccttgac cttgggggca aacaggcggg
    15721 aaagcatgga gcgttccttc ctcgtgatcg tcttctcagg tgggacatta ctccctggga
    15781 gacggctttt cgcgagtgcc cccatgggct taggacaaaa gtccggggtc agactgagac
    15841 tggtggagga acagaccggg gaggtgccgg cgatgccgga gctgtcgcag gagaccgagc
    15901 gcgcgagggc tgccgcgctc ttcggactgg ccgaggtgac cggcccgtcg atggtgccca
    15961 cgctgtacca gggggaccgg ctggtggtgc agtacggcgc ccggatccgg gtcggtgacg
    16021 tgatcgtgct gcggcatccg ttccagcagg acctgctcgt cgtcaagcgg gccgcggagc
    16081 gccgtgaggg cgggtggtgg gtccggggcg acaacaccta cgccggcggc gacagcaccg
    16141 actacgggac cgtgcccgac gaactgatcc tgggccgggt gcggctgcgc taccgcccgc
    16201 cgaagcccgg tcagcgttcg ccgctggcgg tgctgcgctg ggcgctgtcg gcggcgaggc
    16261 ccgtgccggc cgtccggtcc gcctccaggc gcttgcgggc gcggtaggcg gccacgttgg
    16321 cgcgggtggc gcagcggtcg gagcagtagc gccgggagcg gttggtcgag gtgtcgaggt
    16381 aggcgttgcg gcaggggccg gcctcgcaca ggcccaggcg gtcgacgccg tactcggtga
    16441 gatggaaggc caggcccatg gccgcgatgg ccgcgtagcc cgccgtcgcg ttcgacgggt
    16501 ggtcggccag gtgcatgtgc cacagcgggc ggccgtcgtc gtcgcggaag tcgtggccgg
    16561 agatctgcgg gctcaccggg aactccagca ggagcgagtt cagcaggtcc accgcgaggg
    16621 tctcgtcgcc gccgtcggcc gcctcgaaga ccgcgcgcag ccgggcccgg accgcgcgga
    16681 agcgggtgac gtccgcctcg gtggcccgac gacccgccga ctggttgccg ccgaagaggg
    16741 cgcggaccgc ctcgaccgag gtcagcgcgt ccttgccccg ggccggttcc tcgctgttga
    16801 cgaggcgcac ggcgtagtcc gagtaatagg ccagttccac ttgtagtcct tacggtggcg
    16861 ctctatggtc ggggtgcggg cgggggtaac agccgttcgt gcttccaggg tattacgtga
    16921 cgaacacggc ggagggttgc gatgacggac gcgcagacga ccacgaccgg tgccatggac
    16981 ggtgtcacga ccggtgtcac gaccggttcc gcgaccggtg tcacgaccgg tgccgactgg
    17041 gccgcctggc agcggagctg ggaccgccag caggagtggt acatgcccga ccgcgaggaa
    17101 cgattccgga tcatgctcga catggtcgag gggctcgtcg ggcccgcccc gcgcgtcctc
    17161 gacctcgcct gcggcaccgg caccatcacc gcccggctgc tcgcccgcct ccccggcgcg
    17221 accagcaccg gcgtcgacct cgacccggcg ctgctcgcca tcgccgaggg caccttcgac
    17281 ggcgacgacc gcgtcaccct ggtgacggcg gacctcaagg acccggactg gccggcccgg
    17341 ctcccgtacg acacgtacga cgccgtcctg accgccacgg ccctgcactg gctgcacagc
    17401 gaacccctcg ccgccctcta cggtcaggtc gcggaactcg tccgcgacgg cggtgtcttc
    17461 atgaacgcgg accacatgat cgacgacacg acgccccgga tcaacgcggc ggagcgcgca
    17521 cagcgccaca cccgtatgga tcaggccagg gccgacgggg tgctcgactg ggccgagtgg
    17581 tggcagctcg ccgccgagga ccccgtcctc gccgggccga ccgcccgccg cttcgagatc
    17641 tacggcgaac acgccgacgg cgacatgccc tccgcctcct ggcacgctcg cgtcctgctc
    17701 gaacagggct tcagcgaggc tcggcccgtg tgggcgtcac cctccgacac cctgttgctc
    17761 gcgttgcggt gaccgcgccc gtgcaccgac cggaaccggc cagtcggcgc tgacaccctc
    17821 ccggacggcg gaaaggggcg gtacgggatt cccgtaccgc cccttctcgt tcaccgtgtc
    17881 gctacagcac ctcggacagg gtcgctacag caccttggac aggaacgact gggtccgctc
    17941 gtgctgcgga ttcgtcagca cgtcccgcgg gttgccggac tcgaccacca caccgccgtc
    18001 catgaagacc aggctgtcgc cgacctcgcg ggcgaagccc atctcgtggg tgacgacgac
    18061 catcgtcatg ccggactcgg ccaggtcgcg catgacgtcg aggacgtcac cgaccagctc
    18121 cgggtcgagc gccgaggtcg gctcgtcgaa cagcatcagc ttcgggtcca tcgccagcgc
    18181 ccgggcgatg gcgacacgct gctgctggcc gccggagagc tgcgaggggt agccgcccgc
    18241 cttgtccgcc aggcccaccc gctccaggag ctgcatcgcg cgctccttgg cctgggcccg
    18301 gctcgcgccc ttgacctgga ccggagcctc gacgacgttc tccagcgccg tcatgtgcgg
    18361 gaacaggttg aaccgctgga acaccatgcc gatgtcccgg cgcttcagcg cgacctcgct
    18421 gtccttgagc tcgtacagct tgtcgccctt ctggcggtag ccgaccagct cgccgtcgac
    18481 gtaaagccgc ccggcgttga tcttctccag gtggttgatg cacctgagga aggtcgactt
    18541 gccggagccg gaggggccga tgaggcagaa cacctcgccg gacctcacct ccagatcgat
    18601 ccccttgagg acctcgacca ggccgaacga cttgtggacg ccctcggcct tgaccatcgg
    18661 gaccgtggag tccttgacgg acgtggtcgt cttcgcgatc ttctcggtca tgccacgcct
    18721 cccttgctgc ggccgaacga cagcacgttg gccctgatct tctggagggg cgtcggcggc
    18781 aactgacgca gggaaccgcg ggcgtagtac ctctcgaggt agtactggcc gacgctgaag
    18841 atcgaggtca gcaccaggta ccaggccgcg gcgaggaaca gcatctcggc cggggcgccg
    18901 gaggtctggc cgatgtcctg ggcgacccgg agcagctccg agtactggac caccgacacc
    18961 agcgaggtcg tcttcagcat gttgatgacc tcgttgcccg tgggcggcac gatgacgcgc
    19021 atcgcctgcg ggacgacgat cctgcggagc gtcttcgcgt ggctcatgcc cagggcgtgc
    19081 gacgcctcgg tctggccctc gtccaccgac agcagaccgg cacggcagat ttccgccatg
    19141 taggcggcct cgttgaggcc caggccgagc agggcggtca ggaacggggt catgaagtcc
    19201 gaccactcgt tcttgtagat cggcccgagg ttgatgtact cgaagaccag gcccaggttg
    19261 aaccagacga tgagctggac caggaccggg gtgccgcgga agaaccagat gtagaaccac
    19321 gcgatggacg acgtgaccgg gttcttcgag aggcgcatca ccgccagcag aattccgccg
    19381 acgatgccga tcagcatgca cagcaccgtg agcagaagcg tcttgcccac gccgctgagg
    19441 atgcggtcgt tgaagaagta gtccgggatc gccccccagt tgatcctgcc ctgggcgaac
    19501 gcgtagacga tgccggccag cacggcgagg gcgaccacgg cggacacgta ccgcccgtag
    19561 tgccggaccg ggatggcctt gatggcctgc gggccggccg gcggagtgtc cgccgggccg
    19621 tccgccttgt cgatgtcaac agtcacgggt gttgcctttc agtgccgcag accgcgcggt
    19681 cacttgccgc cgttgatggt ggcttccttg acggcgccgt cggcgacgcc ccacttcgtg
    19741 atgatcttct cgtactcgcc gttcgcgatg atcgcgtcca gcgccgcctt cagggcgtcc
    19801 cgcagctcgg tctggtcctt ggcgaccgcg atgccgtagg gggcggcctc gacctgctcg
    19861 ccgaccagct ggaagtcgtt gccgccgcca gaggtcttca cggcgtaggc ggccacgggg
    19921 aagtcggagg agccggcgtc ggcgccgccg ccgcgcaggc gggtctgggc ctgctggtcg
    19981 ttgtcgaagg actcgatggc gatggtcttg ccgccggtgc acttcttggc ctcggacttg
    20041 gcgaggtcct cggagaccgt gccgcgctgc accacgatct tcttgccgca caggtcggac
    20101 caggtcttga tgccctggtc gtcgcccttc ttggtgtaga tcgagacacc ggcggtgaag
    20161 tagtccagga agtcgacgcc ctcgccgacc ttcttgccgg tgtcggagtc gacaccctcc
    20221 tggcggtcct tggtgtcggt catcgcggac atggcgatgt tgtagcggtt cgagcgcaga
    20281 ccggtgatga gggtgtcgaa cgtgccgttc tcgaacttga acgtcacacc gagctgcttg
    20341 cccatcgcgg ccgcgatgtc cgggtcgatg cccacggtct tgccggcgga gtccttgaac
    20401 tcgaccggcg cgtacgcgat gtcggagccg accttgatga cgcccgcgtc ccggatcgcc
    20461 ttcggcagct tgtcggccag cggagccgag ctcgtcgagg ccgagccgct gctctccgag
    20521 tcgctgtcct tggtctggtc cccgcaggcg gtgagcagca aggcgccagc gaccgcgagg
    20581 gatccgaccg ctgccaggcg ggtgcgcgcg gcggtcgtgc gtcgggtgga gcttgcggtc
    20641 atggtggatt cctccggcgg atggatggag atgccgatgg gtcgacaaat gccgatgggt
    20701 cgacgagaac acacaccttc gggtgtcgcg acctcgtgtg atgacggcat cttgccattc
    20761 ggactacgcc attcaggggg ccagccatgt caaaatcgga taacgggcga cccccgaacc
    20821 gcatcactcc ggtacatcac gaccggacgc agccggacca tctgcgggaa tcccccgttc
    20881 cggccgaaag atcttcggtt gatctcatgg tgtgatcgct cggcgtgcgc gctgttcgcc
    20941 gacttgagtc cgtgtcaaga cttcgcggca ccttggcgag acttcgcgca tgagtcatgt
    21001 cactcaaggt gaccgctgtc caaggtccac agagtgagcc atgtgacctt gcacggaat
//
