LOCUS       NZ_LMEQ01000012        21098 bp    DNA     linear   CON 07-JUN-2024
DEFINITION  Streptomyces sp. Root1310 contig_2, whole genome shotgun sequence.
ACCESSION   NZ_LMEQ01000012
VERSION     NZ_LMEQ01000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root1310
  ORGANISM  Streptomyces sp. Root1310
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1120187)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 1120187)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140604
            Assembly Name                     :: Root1310
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001426425.1-RS_2024_06_07
            Annotation Date                   :: 06/07/2024 02:14:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,470
            CDSs (total)                      :: 8,385
            Genes (coding)                    :: 8,123
            CDSs (with protein)               :: 8,123
            Genes (RNA)                       :: 85
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 262
            CDSs (without protein)            :: 262
            Pseudo Genes (ambiguous residues) :: 0 of 262
            Pseudo Genes (frameshifted)       :: 98 of 262
            Pseudo Genes (incomplete)         :: 219 of 262
            Pseudo Genes (internal stop)      :: 20 of 262
            Pseudo Genes (multiple problems)  :: 64 of 262
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:32:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 845391
            Orig. end                         :: 866489
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMEQ01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21098
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="2"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21098
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21098
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11098](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11098
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    38..52
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.79"
                     /tool="antismash"
     gene            complement(221..1561)
                     /gene="aroA"
                     /locus_tag="ASD48_RS21935"
                     /old_locus_tag="ASD48_13475"
     CDS             complement(221..1561)
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130783.1"
                     /locus_tag="ASD48_RS21935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13475"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_057603332.1"
                     /transl_table=11
                     /translation="MAPNPAHTALWPAPHASEAVAATVHVPGSKSVTNRALVLASLASE
                     PGWLRRPLRSRDTLLMAAALREMGVGIEETVSSSSSGAGSPDSTGEAWRILPAGLRGPA
                     TVDVGNAGTVMRFLPPVAALADGPVRFDGDPRSYERPLNGVVDALRVLGARIDDDGRGA
                     LPLTVHGGGALDGGTVEIDASSSSQFVSALLLSAPRFNQGVEVRHTGATLPSVPHIRMT
                     VDMLRAVGAQVDTPESGGEPNVWRVTPGALLGRDLTIEPDLSNAQPFLAAALVTGGRVL
                     IPDWPARTTQPGDRLREIFTEMGGSCELADYGLVFTGSGSIHGIDVDLGEVGELTPGIA
                     AVAALADSPSTLRGVSHLRLHETDRLAALTKEINELGGDVTETADGLHIRPRRLHGGIF
                     HTYDDHRMATAGAIIGLAVEGVQIENVATTAKTLPDFPELWTGMLGV"
     gene            complement(1682..2404)
                     /locus_tag="ASD48_RS21940"
                     /old_locus_tag="ASD48_13480"
     CDS             complement(1682..2404)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="ASD48_RS21940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13480"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_057603333.1"
                     /transl_table=11
                     /translation="MESTAALALPDLWDRLVGTQSDPDLWVVVATAVAALAVVVPHTLW
                     RISRNAITIAHEGGHGLVALLTGRQLTGIRLHSDTSGLTLSRGKPHGLGMILTAAAGYT
                     APPLLGLGGAALLGAGRITLLLWVATALLVVMLVMIRNAYGALTVVLTGGTFLLVSWLA
                     GPQVQAAFAYAVVWFLLLGGVRPAFELQAKRSRGGAGDSDADQLSRLTHVPAGLWLFLF
                     HAVSLCALLGGGRWLLGL"
     gene            2455..3270
                     /locus_tag="ASD48_RS21945"
                     /old_locus_tag="ASD48_13485"
     CDS             2455..3270
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="ASD48_RS21945"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13485"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_057603334.1"
                     /transl_table=11
                     /translation="MCGRYAASRRPEDLAGIFEVEKWEPEEALEPDYNVAPTKEVYAVL
                     DRPLKDAGDKRPVRQLRKLRWGLVPSWAKTPEGGARMINARAETVHEKPSFRRAFAARR
                     CVLPADGYYEWVTGVQERDLEVEGRKKRPRKQPYFVLPADGTVFAMAGLYEFWRDRTLP
                     DDHPRAWWVTCSVITTEAETSPLAVAPADGPHALADIHPRMPLMLTPDRWDAWLDPART
                     DVDDLRSLLEPPPAGLMRAYPVSTAVSNVRNGGPELLKELEGPEEGTLF"
     misc_feature    complement(3279..3294)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 23.28"
                     /tool="antismash"
     gene            3290..3919
                     /locus_tag="ASD48_RS21950"
                     /old_locus_tag="ASD48_13490"
     CDS             3290..3919
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130780.1"
                     /locus_tag="ASD48_RS21950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13490"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_057603335.1"
                     /transl_table=11
                     /translation="MSTETVETEAGTARITWHRAGKPRLVLAVGHGAGGGVEARDLRAL
                     AAVLPGRGVSVALVEQPWRVAGKKVAPAPKTLDVGWRGIWPAVVAPGLPVISGGRSAGA
                     RVACRTATELGAHAVLALGFPLHPPGRPEKSRAGELLGAGVPTLVVQGGNDPFGRPDEF
                     PAGGYDLVEVPYGDHGFAVPKRAGVTQEETLEVVTAAVAGWVASLG"
     gene            4184..4879
                     /gene="sigR"
                     /locus_tag="ASD48_RS21955"
                     /old_locus_tag="ASD48_13495"
     CDS             4184..4879
                     /codon_start=1
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="ASD48_RS21955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13495"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_057603336.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTDNGQAELPEGQGVSRETGAESTAERSARFERDAL
                     EFLDQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINS
                     YRKKQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKAALQAIPEEF
                     RIAVYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARERGLVPAGAGE
                     SNEAKGSGS"
     gene            4876..5178
                     /gene="rsrA"
                     /locus_tag="ASD48_RS21960"
                     /old_locus_tag="ASD48_13500"
     CDS             4876..5178
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020136687.1"
                     /locus_tag="ASD48_RS21960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13500"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_057603337.1"
                     /transl_table=11
                     /translation="MSCGDPHETDCGEVLDHLYEYLDSEMPPVDRDKFQHHFEECSPCL
                     EKYGLEEAVKKLVKRCCGSDDVPTDLRAKVMGRIDLIRSGQAVPEHDVTATPQET"
     gene            5315..6622
                     /locus_tag="ASD48_RS21965"
                     /old_locus_tag="ASD48_13505"
     CDS             5315..6622
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130777.1"
                     /locus_tag="ASD48_RS21965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13505"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_057603338.1"
                     /transl_table=11
                     /translation="MEGSPARARGYAACVALGALLCTLPSLSGARTPWWAVALLAALYA
                     VGERIARRRFAGTLHPVLLAGAFLLSPAAAALVPLPGALFSHVERRPFLLRRVWRAAHA
                     SLAVWAAARVHAAFGGREAVAGSELPYALVPAGAAVLVFCAALALLDGGMLALAEGLPL
                     RRACRGLFLRSLAPLAVHGLGGLMMAVLWLSPYGPVAALLVLFPMAVSWWVFAQYHRER
                     AAHQATIRALVQAVDIKDGYTRGHSERVGQASVLIGRELGMDESRIDMLRFAGILHDVG
                     KLGVPTRLLRKDGPLTPQERRVIELHPEYGHEITRGISFLGEARSAILHHHERLDGKGY
                     PYGLVGSQIPEPARVVAVADAFDAMTSTRSYSRARPVHVALEELRRCAGAQFDPRMVAA
                     LTHAIARDGWHPVVTAEEDRPAVPAQTSDDRSGVRR"
     gene            6619..7857
                     /locus_tag="ASD48_RS21970"
                     /old_locus_tag="ASD48_13510"
     CDS             6619..7857
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130776.1"
                     /locus_tag="ASD48_RS21970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13510"
                     /product="hypothetical protein"
                     /protein_id="WP_057603339.1"
                     /transl_table=11
                     /translation="MTVRRSQVALHAAAALLVGVSLVGTFLTGVENRPVALAFGILVAV
                     GELTRPQSGPRPREAAPLGAAGSLSYALVGGHAGHPTQHGVTQVVAVVVAASLLGSVPQ
                     LARGQAVLDHLVRRVLAVGFAAVCFQPLHNRGVFDGWSGPAYALLLLALLVLTVLCDAV
                     VAAALAHSRTGWPFTPLLRDELRAVPGIGSAVCATGAVMALAVAVVGLWALPVFSVPLL
                     LTQLSLRRYAAVRATYRQTIASLARATEIAGYTPAGHARRVAALSQAVGLDLGLPEPEL
                     AVLEYAALMHDIGQLSLVDPVPAGATAGLPAAQQRRIALLGGAVVRQTGAGAQVAAVVE
                     RQADPYLEQPVAARIVRVVNAYEEKVRGSGPGGPLTALEELRLGTGGEYAPEVVEALAR
                     VLSRRCLTSPVGG"
     gene            7963..8943
                     /locus_tag="ASD48_RS21975"
                     /old_locus_tag="ASD48_13515"
     CDS             7963..8943
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="ASD48_RS21975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13515"
                     /product="hypothetical protein"
                     /protein_id="WP_057603340.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARTAGLRAVALLDREAGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRVPGDAIGAGEPVGMELGSAAVRLSPEGEAEVVWGRRLDPARMEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTSTGHSYPVFDEIELWAPSPVPTWVVLLEAATESDRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGVAAPASLVRGLLDGWVADSPDSRDWRDLEEVC"
     misc_feature    complement(9013..9031)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 18.61"
                     /tool="antismash"
     gene            9068..9718
                     /gene="def"
                     /locus_tag="ASD48_RS21980"
                     /old_locus_tag="ASD48_13520"
     CDS             9068..9718
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="ASD48_RS21980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13520"
                     /product="peptide deformylase"
                     /protein_id="WP_057603341.1"
                     /transl_table=11
                     /translation="MAQQDTDQQHAGVLPVDDEGFVIDTEEAEARELAWREAGTSRPIT
                     VVGNPVLHKECKDVTEFGEELRQLVADMFASQHTAEGVGLAANQIGVDLKVFVYDCPDD
                     EGARHTGVVCNPKLVELPADRRRLDDSNEGCLSVPTAYAPLARPDYAEVTGQDERGNPI
                     KVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYPVVAND"
     misc_feature    complement(9779..9794)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.73"
                     /tool="antismash"
     gene            10001..11098
                     /gene="cyc1"
                     /locus_tag="ASD48_RS21985"
                     /old_locus_tag="ASD48_13525"
     CDS             10001..11098
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007384601.1"
                     /locus_tag="ASD48_RS21985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13525"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_199875917.1"
                     /sec_met_domain="T1TS (E-value: 3.9e-61, bitscore: 203.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAFPYSTTYSTTATVTAPAVPPSLSLPVIEAAFPRQLHPYWPQL
                     QEKTRSWLLEMRLMPADKVAEYADGLCYTDLMAGFYLGAPDEVMQAIADYSAWFFVWDD
                     RHDRDVVHGRTSSWRRLRFRLHAALDCPAEHLRHPDPLVAGLADSVSRLHSFLPGTWNA
                     RFTRHFHAVIDAYDREFHNRIEGRIPGVEEYLALRRLTFAHWIWTDLLEPSAGRELPDP
                     VRKHPAFRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHEGLTLEEAVEEVR
                     RRVEGCISEFLVVEKDVLRLADRLADGTIRGNQLGAAVRCCLGNMRNWFSSVYWFHHES
                     GRYMVDSWDDRSTPPYVNNEAAGEK"
     misc_feature    10895..10897
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11095..12465
                     /locus_tag="ASD48_RS21990"
                     /old_locus_tag="ASD48_13530"
     CDS             11095..12465
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130772.1"
                     /locus_tag="ASD48_RS21990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13530"
                     /product="cytochrome P450"
                     /protein_id="WP_057603342.1"
                     /sec_met_domain="p450 (E-value: 6.6e-67, bitscore: 222.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESMKPATPAAPELREPPLAGGRVPLLGHGWKLARDPLAFLAR
                     LRDHGDIVRLRLGPKTVYAVTAPELTGALALSPDYIISGPLWESLESLLGKEGVATANG
                     PLHRRQRRTIQPAFRLDAIPGYGPIMEEEAYALVERWRGGEVLDVTAEAFRVSVRISAR
                     CLMRGSYMDARSERITSALATLFAGMYQRMVVPLGPLYRVPIPANREFNRALADLHRLV
                     DEIIADRRASGQKPDDLLTALLEAKDENGDPIGEQEIHDQVVAILTPGSETAGSVVMSL
                     LHVLTEHPDQVDKIREEVKSVAGDRPVAFGDVRKLQHTANVVVETMRLYPAVWILTRRA
                     VTETELGGYRIPAGADIVYSPYAVQRDPRSYDRHTEFDPDRWLPGGSPEVPKYAMTPFG
                     VGNRKCPSDHFSMAELTLIAAVVASAFRFEPAPGSDNRTHIGITLRPRRLLLRAVPG"
     gene            complement(12476..13444)
                     /locus_tag="ASD48_RS21995"
                     /old_locus_tag="ASD48_13535"
     CDS             complement(12476..13444)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030121.1"
                     /locus_tag="ASD48_RS21995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13535"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_057603343.1"
                     /transl_table=11
                     /translation="MLKNVAAVLVDGVHPFELGVVCEVFGLDRSDEGLPVYDFAVVSAE
                     GPVLGTHVGGLTVSTPYGLDRLEEADLIAVPAADANIDRAYPPELLAALRRAVDRGARV
                     LSVCSGVFVLGAAGLLDGRRCAAHWRHADVLARRYPRTAVEPDVLYVDEDPVITSAGTA
                     AGIDACLHLVRKEQGPEVANRIARRMVVPPHRAGGQAQYIERPLPRSRCDTVGEVLAWM
                     EQHLDEEVTVEQLAERAHMSPRTFARRFQQETGTTPYRWLLRQRVLLAQHLLEATDETV
                     DAIAWRAGFGTAGALRHQFVQALGTSPNAYRRTFRGPQAVA"
     misc_feature    complement(13427..13443)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.34"
                     /tool="antismash"
     gene            13538..13780
                     /locus_tag="ASD48_RS44810"
                     /old_locus_tag="ASD48_13540"
     CDS             13538..13780
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047586.1"
                     /locus_tag="ASD48_RS44810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13540"
                     /product="hypothetical protein"
                     /protein_id="WP_057603344.1"
                     /transl_table=11
                     /translation="MNTNQIEGLIGMLMVLGILVLLVLPSVLGVVRDRRADRQIREAQE
                     ARGEREGQKSSSRSTVPSTATWYADGRRSKKLVSS"
     gene            complement(13693..14721)
                     /locus_tag="ASD48_RS22005"
                     /old_locus_tag="ASD48_13545"
     CDS             complement(13693..14721)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020130770.1"
                     /locus_tag="ASD48_RS22005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13545"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_057603345.1"
                     /transl_table=11
                     /translation="MTSEANTASAKNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVE
                     EVDLHSDVADLAKLSEGEQHMIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSR
                     QLFEEAVHVQFYLTLLDTYLPDPQDRTAAFDAVENIPSIREKAEFCFKWINEVEKLDRL
                     ETKADRRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHM
                     SFAFEVVDTVRKEEPELFDDQLQEQVTAMLREAVEAELQFGRDLCGEGLPGMNTDSMRQ
                     YLECVADQRLSRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDE
                     DF"
     gene            complement(14721..17099)
                     /locus_tag="ASD48_RS22010"
                     /old_locus_tag="ASD48_13550"
     CDS             complement(14721..17099)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378224.1"
                     /locus_tag="ASD48_RS22010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13550"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_057603346.1"
                     /transl_table=11
                     /translation="MTIAPAEPVSATELETDGPGTALLRTLTELTADLPDADPGRVAAA
                     ALRGRSARAASEVTAELRELATEGAAGLISEDPAYSKLAARLLTISIAAEAASQGVTSF
                     TGSVAVGHREGLIADRTAEFVRVHAVRLDALIDEQADDRFGYFGLRTLHSRYLLRHPIT
                     RKVVETPQHFLLRVAAGLAEDDTSRSLDEVAALYRLMSRLDYLPSSPTLFNSGTRHPQM
                     SSCYLLDSPLDELDSIYDRYHQVARLSKHAGGIGLSYSRIRSRGSLIRGTNGHSNGIVP
                     FLKTLDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLELRDNTGEDARRTHNLNLAHWI
                     PDEFMRRVSADAPWSLFSPADVPELVDLWGEEFDAAYRKAEEAGLAKKTIPARDLYGRM
                     MRTLAQTGNGWMTFKDAANRTANQTAEPGHVVHSSNLCTEILEVTDDGETAVCNLGSVN
                     LGAFVDTAAGTIDWERLDETVRTAVTFLDRVVDINFYPTEQAGRSNARWRPVGLGAMGL
                     QDVFFKLRLPFDSPEAKALSTRIAERVMLAAYEASAELAERNGPLPAWEKTRTARGVLH
                     PDHYGVEFSWPERWAALRERIAQTGMRNSLLLAIAPTATIASIAGVYECIEPQVSNLFK
                     RETLSGEFLQVNSYLVQDLKDLGVWDARTREALRDSSGSVQDLAWIPADVRALYRTAWE
                     IPQRGLIDMAAARTPYLDQAQSLNLFLETPTIGKLSSMYAYAWKSGLKTTYYLRSRPAT
                     RIARAAQAQTPAAIPVQQVTSEEAVACSLENPESCEACQ"
     regulatory      complement(17244..17333)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(17348..17361)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.46"
                     /tool="antismash"
     misc_feature    complement(17355..17369)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(17386..17400)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: strong, score: 25.12"
                     /tool="antismash"
     gene            complement(17411..17917)
                     /locus_tag="ASD48_RS22015"
                     /old_locus_tag="ASD48_13555"
     CDS             complement(17411..17917)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="ASD48_RS22015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_13555"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_057603574.1"
                     /transl_table=11
                     /translation="MDIVIRQVAPGEYEALGDMTARAYLDDGLLDFGESDGYLRELRDV
                     AERAAAAEVLVAVEDGRVLGGVTFVPGPGPMSDIAGRGEAEIRMLAVDGAARGRGAGEA
                     LVRACLDRARAAEGCTAVVLSTQRVMYAAHRIYERLGFVRTPERDWNPMPDRNDLTLIT
                     YQLTL"
     misc_feature    18026..18037
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.48"
                     /tool="antismash"
     misc_feature    complement(18917..18929)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
ORIGIN
        1 gcggccttgc ggcccagttc gcgggccttc atcgcgagga cgatccggtc ctcgacgagg
       61 caggtcaggc ggccccggtc gacggtgagg accatgccct cgacggagtc ctcgtgcttg
      121 gggcggatgt gcgtgcgagg ccggttgccc ttgcggttcg ggcggctgcg gatgtcgtcc
      181 tggtcggtgt gcttgtcata gcggcgcatg gcgaaagtcc ctataccccg agcatcccgg
      241 tccacagttc cgggaagtcg ggcagcgtct tcgccgtcgt cgccacgttc tcgatctgca
      301 cgccctccac ggccaggccg atgatcgcgc cggccgtcgc catgcggtgg tcgtcgtagg
      361 tgtggaagat cccgccgtgc agccggcgcg ggcggatgtg cagaccgtcg gcggtctccg
      421 tcacatcgcc gccgagctcg ttgatctcct tcgtcagcgc ggccagccgg tccgtctcgt
      481 gcaggcgcag atgggacacg ccccgcaggg tggacgggga gtccgcgagg gcggcgaccg
      541 ccgcgatgcc cggggtcagc tcgccgacct cgcccaggtc gacgtcgatg ccgtggatcg
      601 accccgagcc ggtgaagacc aggccgtagt cggccagttc acaggagcca cccatctcgg
      661 tgaagatctc gcgcagccgg tcacccggct gagtggtgcg ggccggccag tccgggatca
      721 gcacccggcc gcccgtcacc agcgccgccg ccaggaacgg ctgggcgttg gacaggtccg
      781 gctcgatcgt caggtcccgg cccagcaggg cgcccggggt gacccgccag acgttcggct
      841 cgccgcccga ctccggggtg tccacctgcg cgcccaccgc gcgcagcatg tcgaccgtca
      901 tccggatgtg cggtacggag ggcagcgtgg cgccggtgtg gcggacctcc acgccctggt
      961 tgaagcgcgg ggccgagagg agcagggccg atacgaactg ggacgaggac gaggcgtcga
     1021 tctcaaccgt cccgccgtcc agcgcgcccc cgccgtgcac ggtcagcggc agcgcgccgc
     1081 ggccgtcgtc gtcgatccgg gcaccgagga cccgcagcgc gtcgacgacg ccgttcaggg
     1141 gtcgctcgta cgagcgaggg tcgccgtcga agcggacggg accgtcggcg agggcggcga
     1201 ccggcggcag gaagcgcatc accgtgcccg cgttgccgac gtcgaccgtg gcgggtccgc
     1261 gcagcccggc ggggaggatc cgccaggcct cgccggtgct gtcggggctg cccgcgccgg
     1321 aggagctgga cgacacggtc tcctcgatgc cgacgcccat ctcgcgcagg gcggccgcca
     1381 tcagcagggt gtcgcgggag cggagggggc ggcgcagcca tccgggctcg gaggcgaggg
     1441 aggcgaggac cagggcgcgg ttggtgacgg acttggaccc cggcacgtgg accgtcgcgg
     1501 cgacggcctc gctcgcgtgc ggggcgggcc agagggcggt gtgtgcgggg ttcggggcca
     1561 tgggccccac tttagtggtc ggccgtcctt cgggtgcggc gccgtcgggg ccggcagcgc
     1621 ccgcggcgga gccgtggacg tcacatcccg caccccggtg acgcgccgct ccggggctgc
     1681 ctcacagccc cagcagccac cggcccccgc ccagcagggc gcacaggctc accgcgtgga
     1741 agaggaacag ccacaggccc gccggtacgt gggtcagccg ggacagctgg tccgcgtccg
     1801 agtcgcccgc gccgccgcgg gagcgcttcg cctggagctc gaaggccggg cggactccgc
     1861 ccagcagcag gaaccacacc accgcgtacg cgaaggccgc ctgcacctgc ggtcccgcca
     1921 gccaggacac cagcaggaag gtgccgccgg tgaggaccac cgtgagggcg ccgtacgcgt
     1981 tgcggatcat caccagcatc acgaccagca gggccgtggc cacccacagc agcagggtga
     2041 tgcggccggc cccgaggagg gcggcgccgc ccaggccgag cagcggggga gcggtgtagc
     2101 cggccgccgc ggtgaggatc atgccgaggc cgtgcggctt gccccggctg agggtcaggc
     2161 cactggtgtc ggagtgcaac cggatcccgg tcagctggcg gccggtcagc agcgcgacca
     2221 ggccgtgacc accctcgtgg gcgatcgtga tggcgttgcg cgatatccgc cacagggtgt
     2281 gcggtacgac gaccgcgaga gcggcgaccg cggtggccac caccacccac aggtcggggt
     2341 cggactgggt gccgacgagg cggtcccaca ggtcgggcag cgcgagggcg gcggtgctct
     2401 ccatgttttc tggtggctcc ctttcggctc acggagtctg gcagtgtggc acgtatgtgc
     2461 ggacggtatg cagcgagtcg caggcccgag gatctcgcag gaatctttga ggtcgagaag
     2521 tgggagcccg aggaggccct ggagccggac tacaacgtgg cgccgaccaa ggaggtctac
     2581 gccgtcctcg accgtccgtt gaaggacgcc ggcgacaagc ggccggttcg gcagctgcgg
     2641 aagctgaggt ggggactggt cccctcctgg gcgaagaccc ccgagggcgg cgcgcggatg
     2701 atcaacgcgc gtgccgagac cgtccacgag aagccctcct tccgccgcgc cttcgccgcc
     2761 cggcgctgcg tcctgcccgc cgacggctac tacgagtggg tcaccggcgt ccaggaacgg
     2821 gacctggagg tcgagggcag gaagaagcgg ccccgcaagc agccctactt cgtgctcccg
     2881 gccgacggca cggtcttcgc gatggccggg ctgtacgagt tctggcggga ccggaccctg
     2941 cccgacgacc atccgcgggc ctggtgggtg acgtgctcgg tgatcacgac cgaggcggag
     3001 acctccccgc tcgccgtggc ccccgccgac ggaccgcacg ccctcgccga catccacccc
     3061 cggatgccgc tgatgctgac cccggaccgc tgggacgcct ggctcgaccc ggcgcggacg
     3121 gacgtcgacg acctccgttc cctcctcgaa cccccgccgg ccgggctgat gcgcgcctac
     3181 ccggtgtcca cggccgtcag caacgtccgc aacggcggcc cggagctgct gaaggagctg
     3241 gaggggcccg aggagggcac actcttctga cgtgagcagt gaaacagtcg tgagcaccga
     3301 aacggtggag accgaggcgg gtaccgcccg catcacctgg caccgggccg ggaagccgcg
     3361 gctcgtcctc gccgtcggcc atggcgccgg gggcggtgtc gaggcccggg acctccgggc
     3421 gctcgccgcc gtgctgcccg gacgcggggt gagcgtcgcc ctcgtcgagc aaccctggcg
     3481 ggtggccggc aagaaggtcg cgcccgcgcc caagaccctc gacgtcggct ggcgcgggat
     3541 ctggccggcc gtcgtcgcgc ccgggctgcc ggtgatctcg ggcggccggt cggccggggc
     3601 gcgggtggcc tgccgtacgg ccaccgagct cggcgcgcac gccgtgctcg cgctcggctt
     3661 tccgctccac ccgccgggca ggccggagaa gtcccgcgcc ggtgaactgc tcggggcggg
     3721 ggtgccgacc ctcgtggtcc agggcggcaa cgaccccttc ggcaggccgg acgagttccc
     3781 cgcggggggc tacgacctgg tggaggtgcc gtacggcgat cacgggttcg cggtgcccaa
     3841 gcgggccggg gtcacgcagg aggagacgct ggaggtcgtc accgcggcag tcgccgggtg
     3901 ggtcgcctca ctcgggtgag gtgaagggtg gggaatgcgg agggggcggg cgctgttgtg
     3961 gcggacaaga agtgctgaac aaccggcacc gacgtcagtg ggagaggaag tccgccgcat
     4021 gggttcgacc atctgcccga gccgcagcag ccgcgccgat ctggactgga cggtgctgca
     4081 cgctgccagg accgctccta ttggagcggc gccgggcgcg ggtagtcgtc tatcctccga
     4141 ttcgagtggg atcggtttcg gtcctacccg cgatcttgag gaggtgggtc cggtcaccgg
     4201 taccgacgca gggaccgaca acggccaggc ggagctgccc gagggccagg gcgtgagccg
     4261 ggagacgggc gcggagtcca ccgccgagcg cagtgcgcgc ttcgagcggg acgcgctcga
     4321 gttcctcgac cagatgtact cggccgcgct gcgcatgacg cgcaacccgg ccgacgccga
     4381 ggacctggtg caggagacgt acgcgaaggc gtacgcgtcc ttccaccagt tccgtgaggg
     4441 caccaacctc aaggcctggc tgtaccggat cctcaccaac accttcatca actcgtaccg
     4501 caagaagcag cgtgaacccc agcgcagcgc ggccgaggag atcgaggact ggcagctggc
     4561 gcgtgccgag tcgcacatgt ccacgggtct gcgctccgcg gagtcgcagg cgctggacca
     4621 cctgcccgac tcggacgtga aggcggcgct tcaggccatc cccgaggagt tccggatcgc
     4681 cgtgtatctc gcggacgtag agggctttgc gtacaaggag atcgcggaca tcatggggac
     4741 acccatcggt acggtgatgt cccggctgca ccggggccgc cgtcaactgc gcggcatgct
     4801 cgaggactac gcccgtgagc gcgggctggt cccggccggt gccggagagt cgaacgaagc
     4861 gaaaggttcg ggctcatgag ctgcggagat ccgcacgaga cggactgcgg tgaggtcctc
     4921 gaccacctgt acgagtacct cgacagcgaa atgcccccgg tggaccggga caagttccag
     4981 caccacttcg aggaatgctc cccctgcctg gagaagtacg ggctggagga ggccgtgaag
     5041 aagctggtca agcggtgctg cgggagtgac gacgtgccga ccgacctgcg ggccaaggtc
     5101 atgggccgga tcgacctgat ccgctccggc caggccgtcc ccgagcatga cgtgacggcg
     5161 acgccccagg agacctgagc cgctttcggg aagcccgctt ccagaaggcg ctgctgtcac
     5221 tcgaatgtgc taatccgagg gtgatacgcc cgcggaccca cccccggccg tcctaggctc
     5281 ctgagcccgg acaggtacgg ctgggggagg cgtcatggaa gggagtccgg cgcgggcgcg
     5341 cggttacgcc gcctgtgtcg ccctcggcgc cctgctctgc acgctcccct cgctgtccgg
     5401 cgcgcgcacc ccctggtggg ccgtcgccct gctcgccgcc ctgtacgccg tcggcgagcg
     5461 gatcgcccgg cgcaggttcg ccggcaccct gcaccccgtg ctgctggccg gggcgttcct
     5521 gctctcgccg gccgcggccg ctctcgtccc gctgcccggg gcgctgttct cgcacgtcga
     5581 gcggcgcccc tttctgctgc gccgggtctg gcgggccgcc cacgcgtcgc tcgccgtgtg
     5641 ggcggcggcc cgggtgcacg ccgcgttcgg cggccgggaa gccgtggccg gctccgagct
     5701 gccttacgcg ctggtgccgg ccggcgcggc cgtgctggtg ttctgcgccg cgctcgccct
     5761 gctggacggc gggatgctcg cgctcgccga ggggctgccg ctgcggcggg cctgccgggg
     5821 gctgttcctg cgctccctgg caccgctggc ggtgcacggg ctcggcggac tgatgatggc
     5881 cgtgctgtgg ctcagcccgt acgggccggt ggccgccctg ctcgtgctgt tcccgatggc
     5941 cgtgtcctgg tgggtgttcg cgcagtacca ccgggagcgc gccgcgcacc aggcgaccat
     6001 ccgcgccctg gtccaggccg tcgacatcaa ggacggctac acgcgcggcc acagcgagcg
     6061 cgtcggccag gcctcggtgc tgatcggccg cgaactgggc atggacgaga gccggatcga
     6121 catgctccgc ttcgccggga tcctgcacga cgtcggcaaa ctcggcgtcc ccacccggct
     6181 gttgcgcaag gacggaccgc tgaccccgca ggagcggcgg gtcatcgagc tgcaccccga
     6241 gtacgggcac gagatcaccc gcgggatctc cttcctcggc gaggcccgct cggcgatcct
     6301 gcaccaccac gaacgcctcg acggcaaggg ctacccgtac gggctggtcg gcagccagat
     6361 cccggagccg gcccgggtgg tcgccgtcgc ggacgccttc gacgccatga cgtccaccag
     6421 gtcctacagc agggccaggc cggtgcacgt cgccctggag gagctgcggc ggtgcgcggg
     6481 cgcccagttc gacccccgga tggtcgcggc gctgacgcac gccatcgccc gggacggctg
     6541 gcatcccgtc gtgaccgccg aggaggaccg gccggccgtg cccgcgcaga cctccgacga
     6601 ccggtccggg gtacgccgat gaccgtccgc cgctcgcagg tcgccctcca tgccgcggcc
     6661 gcgctgctcg tcggcgtctc cctggtcggc accttcctga cgggggtcga gaaccgcccc
     6721 gtcgcgctcg ccttcgggat cctcgtcgcc gtcggggagc tgacccgccc ccagagcggg
     6781 ccccggccgc gggaggccgc gcccctcggt gccgccgggt cactctcgta cgcgctggtc
     6841 ggaggacatg ccgggcatcc cacgcagcac ggggtgaccc aggtcgtggc ggtggtggtc
     6901 gccgcctcgc tgctcggcag cgtgccgcag ctggcccgtg gacaggccgt cctcgaccac
     6961 ctggtccggc gggtgctggc cgtcgggttc gccgccgtct gcttccagcc cctccacaac
     7021 cgcggggtgt tcgacggctg gagcgggccc gcctacgcgc tgctgctgct cgcgctgctc
     7081 gtcctgaccg tgctgtgcga cgccgtggtc gccgccgcgc tcgcccactc ccgtaccggc
     7141 tggccgttca ccccgctgct gcgggacgag ctgcgggcgg tgcccgggat cggctcggcg
     7201 gtctgcgcga cgggggcggt gatggcgctc gcggtggccg tagtcgggct gtgggcgctg
     7261 ccggtgttct cggtgccgct gctgctcacc cagctgtccc tgcgccggta cgcggcggtg
     7321 cgggccacct accggcagac catcgcctcg ctggcccgtg ccacggagat cgccgggtac
     7381 accccggccg ggcatgcccg ccgggtcgcc gccctcagcc aggccgtggg tctggacctg
     7441 gggctgccgg agcccgagct ggccgtgctg gagtacgcgg ccctcatgca cgacatcggc
     7501 cagctcagcc tcgtcgaccc ggtcccggcg ggtgccaccg ccgggctgcc ggccgcccag
     7561 cagcggcgga tcgcgctgct cggcggggcc gtcgtccgcc agaccggtgc gggcgcacag
     7621 gtcgccgcgg tcgtcgagcg gcaggccgat ccctacctgg agcagccggt ggccgcgcgc
     7681 atagtccggg tggtgaacgc atacgaggag aaggtccggg gcagcggacc cggtgggccc
     7741 ctcaccgccc tggaggagct gcgcctcggc accggcgggg agtacgcgcc cgaggtggtg
     7801 gaggccctgg ccagggtgct ttcgcggcgt tgtctgacct cgcccgtggg tgggtaaccc
     7861 atgggtaatg agcggccctc cggccacacg tggttggatg cgagggagag agtgtccggg
     7921 ggcactggcc agcccacaga acggaactgg caggcgggaa tcgtgaggat cttcggcaag
     7981 ggacggcacc ggccctccgc ctcctggcgg caggccaccg accgcgcgtt cacgctgatc
     8041 ggcgacgggc ggtacgagga cgcgggcgcg ctgctgacac gtgccgccga cctggagccc
     8101 tggctgtccg agtcctggtt caacctcgcc ctgctgcaca agttccggca cgactgggag
     8161 caggcccgca cggcggggct ccgggccgtc gccctgctcg accgcgaggc cggcgccccc
     8221 gactggtgga acgtgggcat cgcggccacc gccctccagg actggccgct ggcccgccgc
     8281 gcctggcagg cgtacgggct gcgggtgccc ggcgacgcca taggcgcggg cgagccggtc
     8341 ggcatggagc tgggcagcgc ggccgtacgg ctgtcgcccg agggcgaggc cgaggtggtg
     8401 tgggggcggc ggctggaccc cgcccggatg gaggtgctgt ccatcccgct gccctcgtcc
     8461 gggcggcgct ggggcgaggt cgtgctgcac gacggggtgc cgcacggcga gcggaccacg
     8521 tccacgggcc actcctaccc ggtcttcgac gagatcgagc tgtgggcgcc ctctcccgtg
     8581 ccgacctggg tcgtcctgct ggaggcggcc accgagtcgg accgggacgc gctggagcag
     8641 ctggcggccg acgcgggctt cgcggcggag gactggtcgt cgtcggtgcg gctgctctgc
     8701 cggatgtgct cggagtcgcg gatgccgtcc gacgagggtg acggcgagca tctcgacccg
     8761 cacgaccaca gtgagccggg acacccgggc ccgctcgggc accggacgga cggccagctg
     8821 tgggtgccgg agcgggagtg cggggtggcc gcgccggcct ctctcgtacg cggcctgctg
     8881 gacgggtggg tcgccgacag ccccgattcc agggactggc gggacctgga agaggtctgc
     8941 tgaccgcttt ccgccgcgcg tttcgtcgtg gctggtcgcg ccgttccccg cgccccgcag
     9001 gggcgcgctg cccgtaccct gtatcgagca ttcaccccct gtctgtttga ggaaggcatc
     9061 gtcggtcatg gcccagcagg acaccgatca gcagcacgcg ggcgtgctcc ccgtggacga
     9121 cgagggcttc gtcatcgaca ccgaggaggc ggaggcgcgc gagctggcat ggcgtgaggc
     9181 cggcacctcg cggccgatca ccgtcgtcgg gaacccggtg ctgcacaagg agtgcaagga
     9241 cgtcaccgag ttcggcgagg aactgcggca gctggtcgcg gacatgttcg cctcgcagca
     9301 caccgccgag ggagtgggcc tggccgccaa ccagatcggc gtcgacctca aggtcttcgt
     9361 ctacgactgc ccggacgacg agggcgcccg gcacaccggc gtcgtctgca acccgaagct
     9421 ggtcgaactg cccgccgacc ggcgcaggct ggacgacagc aacgagggct gtctgtcggt
     9481 gcccaccgcc tacgcgccgc tggcgcgtcc cgactacgcc gaagtgaccg ggcaggacga
     9541 gcggggcaat ccgatcaagg tgcgcggcac cggttacttc gctcggtgtt tgcagcacga
     9601 gaccgaccac ctgtacggct acctctacat cgaccgtctg tccaagcgtg aacgcaagga
     9661 cgccctgcgg cagatggccg agaacgagcc ccgttatccc gtggtcgcca acgactgagc
     9721 ccacccgcac caccacgacg cccggccggg atccttccgg ccgggcgtcg ttcgtgtgtc
     9781 cgacggacgt tcgatcgctt acgcacatct actgcacatc tgctgatccg taaccagtca
     9841 cgcaggggcg gattctcggc atgtggggtg gtgaatgaag caaatccgtt cccagaacgg
     9901 tcagttgtag tgctgaatgg gaagtgcggg gatacgcaac ggcgcacgcc cggcacgggg
     9961 cgaggggtgt gtgcccactg gcggctgaga ggggttgtcc gtgccagctt tcccatacag
    10021 caccacatac agcaccacag cgacggtgac cgcgcccgcg gtccctccct cgctctctct
    10081 tccggtcatc gaggcggcgt ttccccggca actgcatccg tattggcctc agttgcagga
    10141 gaagacgcgc tcctggctgc tggaaatgcg gttgatgccg gcggacaagg tcgcagaata
    10201 tgccgacgga ctttgctaca ccgacctgat ggcgggcttc tacctcggcg caccggacga
    10261 ggtcatgcag gccatcgccg actacagcgc gtggttcttc gtctgggacg accggcacga
    10321 ccgtgacgtc gtgcacggcc ggacgtcctc ctggcggcgg ctcaggttcc gcttgcacgc
    10381 ggccctggac tgcccggcgg agcatctgcg ccacccggat ccgctggtcg ccgggctcgc
    10441 ggacagtgtg agccggctcc actccttcct tcccggtacc tggaacgccc ggttcacccg
    10501 gcacttccac gccgtgatcg acgcatacga ccgggaattc cacaaccgaa tcgaagggcg
    10561 cattccagga gtcgaggaat acctggcgct gcgtcggctc accttcgcgc actggatctg
    10621 gaccgacctg ctggagccga gcgcgggacg tgaactcccg gacccggtgc gaaagcaccc
    10681 cgcatttcgc cgggcggcgc tgctgagtca ggaattcgcc gcctggtaca acgacctctg
    10741 ctcacttcca aaggaaatag cgggcgatga ggtgcacaat ctcggaatca gtctcatcac
    10801 tcatgaggga ctgaccctgg aagaggcggt ggaggaagtc aggcgacgcg tcgagggatg
    10861 catttccgag ttcctcgtcg tcgagaagga cgtcttacgg ctcgccgacc ggctggccga
    10921 cgggacgatc cgcggaaatc aactcggcgc cgccgtgcgg tgctgcctcg gcaatatgcg
    10981 gaactggttc agttccgtct actggttcca ccacgagtcc ggccggtaca tggtcgacag
    11041 ctgggacgac cggtccacgc ccccgtacgt caacaacgaa gcggcaggtg agaaatgacc
    11101 gtcgagtcga tgaaacccgc gacccccgcg gcgcccgaac tgcgtgagcc accgttggcc
    11161 ggtggcaggg ttccgctcct cggacacggc tggaagctgg cccgtgaccc gctggccttc
    11221 ctggcccgac tgcgcgacca cggcgacatc gtccgcctcc ggctcggccc caagacggtg
    11281 tacgccgtca ccgcgccgga gctcaccggc gccctggcgc tcagcccgga ctacatcatc
    11341 tcggggcccc tgtgggagtc cctggagagc ctgctcggca aggagggcgt ggccacggcc
    11401 aacggcccgc tgcaccgccg ccagcggcgc acgatccagc ccgcgttccg gctcgacgcg
    11461 atccccggct acgggccgat catggaggag gaggcgtacg cgctcgtcga acgctggcga
    11521 gggggcgagg tcctcgacgt caccgcggag gccttccggg tgtccgtgcg catctccgcg
    11581 cgctgtctca tgcgcggcag ctatatggac gcccggtccg agcgcatcac gtcggcgctc
    11641 gccaccctgt tcgccggtat gtaccagcgc atggtggtgc ccctcggccc gctttatcgg
    11701 gtaccgattc cggccaaccg cgaattcaac cgggcgctgg ccgatctgca tcggctggtc
    11761 gacgagatca ttgccgaccg tcgtgcatcc ggtcaaaaac cggacgattt gctgacggct
    11821 ttgctggagg cgaaggacga gaatggtgac ccgatcgggg aacaggagat ccacgaccag
    11881 gtcgtggcga tactcacacc gggcagcgaa acagccggct ctgtggtcat gtcgctgctc
    11941 catgtcctca ccgagcaccc cgaccaggtg gacaagatcc gcgaagaggt gaaaagcgtc
    12001 gccggtgacc ggccggtcgc attcggcgac gtccgaaagc tccagcacac cgccaatgtc
    12061 gtcgtcgaga ccatgcggct gtatcccgcc gtatggatat tgacccggcg cgcggtgacc
    12121 gagaccgagc tcggcggcta ccgcattccc gcgggcgccg acatcgtcta cagcccgtac
    12181 gccgtacagc gcgatccgcg gtcgtacgat cggcacacgg agttcgatcc cgaccgctgg
    12241 ctgcccggcg gctccccgga ggtgccgaag tacgccatga cgccgttcgg cgtcggcaac
    12301 cggaagtgcc cgagcgacca cttctcgatg gccgagctga cgctgatcgc cgcggtggtg
    12361 gcgtcggcgt tccgcttcga gccggcgccg ggctccgaca accggacgca catcggcatc
    12421 acgctccgac cgcgcaggct gctgctgcgg gcggtgcccg ggtgagagcc gcggctcagg
    12481 cgacggcctg cgggccgcgg aacgtgcgcc gataggcgtt gggggacgtc cccagcgcct
    12541 gcacgaactg gtggcgcagg gcaccggccg taccgaagcc ggcgcgccag gcgatcgcgt
    12601 ccaccgtctc gtccgtcgcc tccagcaggt gctgggccag cagcacccgc tgacgcagca
    12661 gccaccggta gggggtggtg cccgtctcct gctggaaccg gcgggcgaag gtgcgcggtg
    12721 acatgtgggc gcgttccgcg agctgctcca ccgtgacctc ctcgtcgagg tgctgctcca
    12781 tccacgcgag cacctcgccg acggtgtcgc accgcgaccg gggcagcggc cgctcgatgt
    12841 actgggcctg gccgccggcc cggtgcggcg gcaccaccat ccgccgggcg atccggttgg
    12901 cgacctcggg cccctgctcc ttgcggacca ggtgcagaca ggcgtcgatg ccggcggccg
    12961 tgcccgccga ggtgatcacc gggtcctcgt cgacgtacag cacgtccggc tcgacggccg
    13021 tccgggggta gcgccgggcc agcacgtccg cgtgccgcca gtgcgcggcg cagcgccggc
    13081 cgtcgagcag ccccgcggcg cccagcacga acaccccgga gcagacgctg agcacccggg
    13141 caccccggtc cacggcccgg cgcagcgcgg cgagcagctc gggcggatac gcgcggtcga
    13201 tgttcgcgtc cgcggccggt acggcgatca ggtcggcctc ctccagccgg tcgaggccgt
    13261 acggcgtgga cacggtgagt ccgccgacgt gggtgcccag gaccgggccc tccgccgaca
    13321 ccacggcgaa gtcgtacacc ggtagacctt cgtcgctccg gtcgaggccg aacacctcgc
    13381 agacgacgcc gagttcaaag ggatgcacac cgtcgaccag gacggcggcc acgtttttca
    13441 gcatgctgcc agtgtgcacc cgcggtggca ggaatttgaa ggtgtgcggc agtcctgcca
    13501 ctcacggtca ggggcgtccg gcacaacact ggtgtccatg aacacgaacc agatcgaagg
    13561 cctcatcgga atgctcatgg tcctcgggat cctcgtcctc ctggtcctcc cgtccgtgct
    13621 cggcgtcgtg cgcgaccggc gcgccgaccg gcagatcagg gaggcccagg aggcccgggg
    13681 cgagcgggag ggtcagaagt cctcgtccag gtcgacggtg ccctccaccg cgacctggta
    13741 cgccgacgga cggcgctcga agaagttggt cagctcctga acaccctgga gctccatgaa
    13801 ggagaagggg ttctccgagc cgtacaccgg ggcgaacccg agccgcgaca gacgctggtc
    13861 ggcgacacac tcgaggtact gccgcatcga gtcggtgttc atgcccggca gcccctcgcc
    13921 gcacaggtcg cgcccgaact ggagctcggc ctcgacagcc tcccgcagca tggcggtcac
    13981 ctgctcctgg agctggtcgt cgaagagttc cggttcctcc ttgcggacgg tgtcgaccac
    14041 ctcgaaggcg aagctcatgt gcatcgtctc gtcacggaac acccagttgg tgcccgtggc
    14101 gagaccgtgc agcagacccc ggctgcggaa ccagtagacg tacgcgaagg cgccgtagaa
    14161 gaacaggccc tcgatgcacg cggcgaagca gatcaggttg agcaggaagc ggcggcggtc
    14221 ggccttggtc tccagccggt ccagcttctc gacctcgttg atccacttga agcagaactc
    14281 ggccttctcg cggatggacg ggatgttctc gaccgcgtcg aaggccgccg tcctgtcctg
    14341 cggatccggg aggtaggtgt ccaggagcgt cagatagaac tggacgtgga cggcctcctc
    14401 gaagagctgc ctcgacaggt agaggcgtgc ctcgggggag ttgatgtgct tgtacagcgt
    14461 cagcacgagg ttgttcgcca cgatcgagtc gcccgtcgcg aagaacgcga ccagccggcc
    14521 gatcatgtgc tgttcgccct cggacagctt cgccaggtcg gcgacgtccg agtggaggtc
    14581 gacctcctcg acggtccagg tgttcttgat ggcgtcccgg taacgctcgt agaagtccgg
    14641 gtagcgcatc ggccggaggg tcagctcgaa gcccgggtcg agcaggttct tggcggacgc
    14701 ggtgttggct tcgctggtca ttactggcag gcctcgcagg actcggggtt ctcaagggag
    14761 caggcgacgg cctcttccga ggtcacctgc tgcacgggga tggcggcggg cgtctgcgcc
    14821 tgggccgcgc gggcgatccg ggtcgccggg cgggagcgca ggtagtacgt cgtcttcagg
    14881 cccgacttcc aggcgtacgc gtacatcgag gagagcttgc cgatggtcgg cgtctccagg
    14941 aacaggttca gggactgcgc ctggtccagg tacggggtgc gggcggcggc catgtcgatc
    15001 aggccgcgct gcgggatctc ccacgccgtg cggtacaggg cgcgcacgtc cgccgggatc
    15061 caggcgaggt cctgcaccga gccgctggag tcgcgcagcg cctcacgggt gcgggcgtcc
    15121 cagacaccga ggtccttgag gtcctgcacc aggtaggagt tgacctggag gaactcgccg
    15181 gacagcgtct cgcgcttgaa caggttggac acctgcggct cgatgcactc gtacacgccc
    15241 gcgatggacg cgatggtggc ggtgggggcg atggcgagga gcagggagtt gcgcatgccg
    15301 gtctgcgcga tccgctcgcg cagggccgcc cagcgctccg gccagctgaa ctcgacgccg
    15361 tagtggtccg ggtgcagcac gccccgggcc gtacgggtct tctcccaggc cggcagcggg
    15421 ccgttgcgct cggccagctc ggcggaggcc tcgtaggcgg cgagcatgac gcgctcggcg
    15481 atccgggtgg acagcgcctt cgcctcgggc gagtcgaagg gcagccgcag cttgaagaag
    15541 acgtcctgga ggcccatcgc gcccaggccg accggacgcc agcgggcgtt ggagcggccc
    15601 gcctgctcgg tcgggtagaa gttgatgtcg acgacccggt cgaggaaggt gaccgccgtg
    15661 cggacggtct cgtccagccg ctcccagtcg atcgtgccgg ccgccgtgtc gacgaacgcg
    15721 ccgaggttca ccgaacccag gttgcagacc gccgtctcgc cgtcgtccgt gacctccagg
    15781 atctccgtgc agaggttgga ggagtgcacg acgtgacccg gctcggccgt ctggttggcg
    15841 gtgcggttgg ccgcgtcctt gaaggtcatc cagccgttgc cggtctgcgc gagggtgcgc
    15901 atcatgcggc cgtagagatc acgggccggg atggtcttct tcgcgaggcc cgcctcctcg
    15961 gccttgcggt aggccgcgtc gaactcctcg ccccacaggt cgacgagctc cggcacgtcg
    16021 gcgggggaga acagcgacca gggggcgtcg gcgctgaccc ggcgcatgaa ctcgtccggg
    16081 atccagtgcg cgaggttcag gttgtgcgtc cggcgggcgt cctcaccggt gttgtcacgc
    16141 agctccagga actcctcgat gtcggagtgc caggtctcca ggtagaccgc cgccgcgccc
    16201 ttgcgccggc cgccctggtt caccgcggcg accgaggcgt cgagcgtctt caggaacggc
    16261 acgatgccgt tggagtgccc gttggtgcca cggatcagcg aaccgcggct gcggatacgg
    16321 gagtacgaca gtccgatgcc gcccgcgtgc ttggacagcc gggccacctg gtggtagcgg
    16381 tcgtagatgg agtccagctc gtccagcggc gagtcgagga ggtagcagga cgacatctgg
    16441 gggtgccggg taccggagtt gaagagcgtg ggggaggacg gcaggtagtc caggcggctc
    16501 atcagccggt agagcgcggc gacctcgtcc agggaacggg aggtgtcgtc ctcggcgagg
    16561 ccggcggcga cgcgcagcag gaagtgctgc ggtgtctcga cgaccttgcg ggtgatcggg
    16621 tgccgcagga gatagcggct gtgcagggta cgcagcccga agtagccgaa gcggtcgtcg
    16681 gcctgctcgt cgatcagggc gtcgaggcgg accgcgtgga cacgcacgaa ctcggctgtg
    16741 cggtcggcga tcaggccctc gcggtggccg acggcgaccg atccggtgaa cgacgtgacg
    16801 ccctgggagg cggcctccgc ggcgatgctg atcgtcagca gccgggcggc cagcttcgag
    16861 taggcggggt cctcggagat caggcccgcg gccccctccg tggccagctc gcgcagctcc
    16921 gcggtgacct cggaggcagc ccgcgcggac cggccgcgca gggcggcggc ggcgacccgg
    16981 ccggggtcgg cgtcgggcag gtcggcggtc agctcggtca gggtccgcag caacgcggta
    17041 ccgggaccgt cggtctccag ctcggtggcg gaaaccggct cggctggcgc gatggtcacg
    17101 tggggctctc cctcgctcgg cgatgggcct tgcgcagggc agggggcagc acacgagcgc
    17161 gcggggcgtc gcgtccaccg gcccactcca cgagacccgg acgtcagggc acccggaccg
    17221 gacggccggg cgcgctgtcg gcaggacctc ggactgaaca ggcgtgcgca tacgggtatg
    17281 gatgcacgcg agtacaccgt tgcgggacag ttccggattc gcaccggatt cccctgcggc
    17341 gacagcgagc atgagcatac atcttgtgct cacctgtcac gccaccccca gatgttgtgt
    17401 cggggtggtt tcagagcgtc agctgatagg tgatcagggt gagatcgttc cggtccggca
    17461 tggggttcca gtcccgctcg ggtgtgcgga cgaaacccag acgttcgtag atgcggtggg
    17521 ccgcgtacat cacgcgttgg gtcgacagga cgacggcggt gcagccctcc gcggcccggg
    17581 cgcggtcgag gcaggcgcgg acgagggcct cccccgcacc ccggccgcgg gcggccccgt
    17641 cgaccgcgag catgcggatc tccgcctcgc cgcggcccgc gatgtcggac atggggccgg
    17701 ggccggggac gaaggtgacg ccgccgagga cacggccgtc ctccacggcc accagcacct
    17761 cggcggccgc cgcgcgctcg gccacgtcgc gcagttcgcg cagatacccg tcgctctcgc
    17821 cgaagtcgag gaggccgtcg tcgaggtagg cgcgggcggt catgtcgccg agggcctcgt
    17881 actcgcccgg cgcgacctgc cgtatcacga tgtccatggc cccgagtgtg ccggacgccc
    17941 gggttgcgga gcgtgccggg agtgattcca tggaagaagg cgtcggcgcc gtgcgaatcc
    18001 tctgctccgc gagtcctccg tcccggaaac cgctttctcg ggacgtgcaa ggagaacgcc
    18061 atgacgaggg tcgtccgcca tccccccggc aaggagcggc cgcgcgacgc gccgatggcc
    18121 acactggtct tccgacgggc ggggcaccgg gtcggacacg gcctcgtcgg ccgctggcac
    18181 gccctgacga tccgtctgga ggcccgccgc ggcgccaccc gacccaagaa gtggcgccgg
    18241 tgtgtctcct acgccaacgt caccaggatg atctggctgg ttgccgtgct ggcgctgctt
    18301 gcctgggtcg gcgagggcct gttcatcctc gtcacgcacg acacgaccgg gttcgagcag
    18361 tggcggcagg gcaacgacgg gttcgagacc gtcttcaagt tcgtcggccc ggtcctcgcc
    18421 gcctcgatcg ccgccgcgct cttcctgttc tggtggtatc gctggaccaa acagcgctat
    18481 ctcaccaagg ccttgcggga cccgcgccgg ctggtgccca ccgccgggta cgacaccgcc
    18541 gagatcgtgg gccgcgagga catcgcccag gtcatcgccg agcggctgcg cgaacgcgac
    18601 acgcggcggc cgtatctgct cgtcggcggc gtcggagcgg ggaagaccgc cgtcctcgta
    18661 cggctcaccg aactgctggc ccgtcagcac gccgtaccgg tgccggtcag actgcgggac
    18721 gccgccgacg gctccgacct gaacttcgaa cgcctggcga ggcagcgctt cgctcaggag
    18781 gcgcccaagg gcatcctggc gcgcagcaag accgaccggg tgtggcaaca actcctcgcc
    18841 gacgacaagc cggtcgtcct ggccgacggc ctggaggagg cccttctcga cgacggcgac
    18901 ggccggcagc acaaccggga caacgtcatc cgccgggcca tcgagcgcgc ccgcgaggag
    18961 aagctgcccc tggtcatcgc ctcccggccg cacagcccgc tggagaccac ctccgccgcg
    19021 atcgtggtgc tggaaccgct cagcgaggag gaggcgctgc gcttcatcga ggcggacgta
    19081 ccggagaccg acgagcgccg ggtggactgg atcgtggaga cggcggaggt gaccgagtcg
    19141 ccgatctacc tccagatcgc ccgtgaactc caccggcggg gagtcctgga gcacgaccgc
    19201 ccggacggcg atccacggca catgaacacc cgcagccgcg accgcgccac cctgcggctc
    19261 tggctcctgg agacctgggc cgaggcgctg tgcgagggaa agctgcgcga ggatgtcgcg
    19321 ctgaacccgc aggagcgccg tgacacgctc gaagcggtct cggccctggc ctgtgtcgga
    19381 ctgctccagg acaagctgga ggtcggattc gccgagctgc tcgacccgga ggtcctgcac
    19441 cccggtccgg cacggcgcgc gcgggcccgg gccgagcacg tgtgggccgg ccgcggcttc
    19501 gaccggtacg gcaagcgcgg gatcaccctc tccgactggc accggcgccg gatctgggac
    19561 gcgctgtgcg aacggctcgg cgagacggag cgacggcggc tgcgcgaggg gaacatggac
    19621 cagtgccatg ccgtcctcgc ccgcttcgcc gcccgcgcgg gcaagctcag actggtggag
    19681 ggcttcgagc acagggtccg cttcccgcac agcatcatcc aggcctactt cggttgtcgg
    19741 ctgctgaacc acctcgggga gcggggcgcc ggagacctgg ccgagcaggc gcttcagccg
    19801 cccggcccca gtcgcgaact gctcatcgcc ctcgtcctgc tgtcccgtgg cagggtggcg
    19861 cacgctccgg cccggggaca cggcgtgcgg gccgagatac ggaaggagat ggcggaactg
    19921 ctgcggcaga cgcccgtgcg gggccgcccg ctcgcccacc ggctgtgcgc cgccgcgggc
    19981 cgccgcaccg acgaccccaa ggccctggat ctctacgcgg ccgccctgga gatcgagagc
    20041 gccgaggacg acccgggaga gctgagcgcg atcgtcaccg cggtgcgtga acactgggcc
    20101 ggtatcaagg gtgaccggcg caccctgagg gacgccaagc gcagagtgct caaacaactg
    20161 ggttccgcgc tgcggaaggt gtccgaccgg atcgacacca cgcccttgta ctgggagctg
    20221 ttccgactgg gcatccagga accctcctac tccatccgcc tggtggtcgc ccaggaggtc
    20281 ggcaccggtg gcaacgcggc gttcgccgtg atccgcgagc gggtcggcct gaacagcgac
    20341 cccgtgaacg agtacaacga ccggctggaa gagctgaagg cctggaagag acgggagtac
    20401 gaggcgtggt ccgtgcgcat ggggcaggcg cacgcggacc gtatgtcccc ggggggcgct
    20461 tcggccgagg acctcgggcg gttgcaggag gaccgcaagg aactgaaccg gcgctaccgc
    20521 gagcgacggg tcgatctctt ccgggagttc gtgatgcggg cctggatgct cccgatgctc
    20581 ctgggctccg tcgacgaggc ccatcgcgac gaggcccggg aacgcctcac caagtggctg
    20641 cgccacctcg acccggagtt caccggcggc gcccccgatc tgccgctcgc cctggaggcc
    20701 gcgctggccc agggcttcaa gtacgcggcc aaccggcgcc atcgacaccc gcgcacccac
    20761 ccgggcggcc gcaacgacct gatccgccag gcggagaccg tgctccggca gtcacgctgc
    20821 tggtacgcgc agctcagcct gctccaggcg ctgtgtctgt gggagctccc ggacgctgtc
    20881 ggcggccggg ccgacgggca ccagccgatc cagcggttcg gcggggccac cgccgtacag
    20941 acggtgcagc gctggctggc gatggcgggc acggtgaacg gggcgccggg gcacccggac
    21001 cggcccggtg aaccggcccg gcggtgcctg catccgttcg tcgccgaggc cggcgacctg
    21061 gtcgccctcg ccctggagac cggacagccc gagcggtt
//
