LOCUS       NZ_LMEQ01000012        38857 bp    DNA     linear   CON 07-JUN-2024
DEFINITION  Streptomyces sp. Root1310 contig_2, whole genome shotgun sequence.
ACCESSION   NZ_LMEQ01000012
VERSION     NZ_LMEQ01000012.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root1310
  ORGANISM  Streptomyces sp. Root1310
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 1120187)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 1120187)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140604
            Assembly Name                     :: Root1310
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001426425.1-RS_2024_06_07
            Annotation Date                   :: 06/07/2024 02:14:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,470
            CDSs (total)                      :: 8,385
            Genes (coding)                    :: 8,123
            CDSs (with protein)               :: 8,123
            Genes (RNA)                       :: 85
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 262
            CDSs (without protein)            :: 262
            Pseudo Genes (ambiguous residues) :: 0 of 262
            Pseudo Genes (frameshifted)       :: 98 of 262
            Pseudo Genes (incomplete)         :: 219 of 262
            Pseudo Genes (internal stop)      :: 20 of 262
            Pseudo Genes (multiple problems)  :: 64 of 262
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:32:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 648723
            Orig. end                         :: 687580
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMEQ01000012.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..38857
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NAPAA"
                     /region_number="1"
                     /rules="(AMP-binding and TIGR02353)"
                     /tool="antismash"
     cand_cluster    1..38857
                     /SMILES="NC([*])C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(AMP-binding and TIGR02353)"
                     /kind="single"
                     /product="NAPAA"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..38857
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="False"
                     /core_location="[15000:23857](+)"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      15001..23857
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(AMP-binding and TIGR02353)"
                     /neighbourhood="15000"
                     /product="NAPAA"
                     /protocluster_number="1"
     gene            complement(211..591)
                     /locus_tag="ASD48_RS21140"
                     /old_locus_tag="ASD48_12685"
     CDS             complement(211..591)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASD48_RS21140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ASD48_12685"
                     /product="hypothetical protein"
                     /protein_id="WP_157880660.1"
                     /transl_table=11
                     /translation="MTDSTPSEPIPEDGEPTAFAKAKGWVSKHKPKILAVAGTVGSAAL
                     AVAVLAARHAEEQNVAEESQDTGSAADSAEEKEQRNPPTKHNVAPHKRRLADGREIDVS
                     GYERGGSSEDEDEDEDPGEAAA"
     gene            961..3393
                     /locus_tag="ASD48_RS21145"
                     /old_locus_tag="ASD48_12690"
     CDS             961..3393
                     /EC_number="2.1.1.72"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0009007 - site-specific
                     DNA-methyltransferase (adenine-specific) activity [Evidence
                     IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015573302.1"
                     /locus_tag="ASD48_RS21145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12690"
                     /product="type I restriction-modification system subunit M"
                     /protein_id="WP_079073882.1"
                     /transl_table=11
                     /translation="MALKKTDLYSSLWKSCDELRGGMDAGQYKDYILTLLFVKYVSDKA
                     KADPDSLIDVPPGGSFDDMVAAKGDKEIGDRFNKIVSRLAEANDLRNVIDLADFNDEEK
                     LGKGKEIQDRLSKLVTIFSDLDFRGSRAEGDDLLGDAYEYLMRHFATESGKSKGQFYTP
                     AEVSRVLAKVVGITKDTRQDQTVYDPTCGSGSLLLKVAAEAPRGITIYGQEKDNATWAL
                     SKMNMILHGNEDAEILKGDTITSPQFTNGNALQTFDFAVANPPFSIKSWSNGLEQEYGR
                     FEYGRPPEKNGDYAFLLHILKSLKSTGKAAVILPHGVLFRGNAEADIRQRLLKQGFIKG
                     IIGLPANLFYGTGIPACIIVLDKENAVGRTGVFMIDASKGFIKDGNKNRLRSQDIHKIV
                     DVFTRQTTIDRYSRMVPLSEIADPKNDYNLNIPRYIDSSEPEDIQDLHAHLHGGIPNRD
                     LDALSGYWDAFPQLRDQLFRLNRPGYSDLTIDVSQVQQAILDSPEFQKFTQEARELTTE
                     WFAAHRKRLEGIDETTRPNDLIAVLGDDLLARFKPVPLLDEYDVYEQLMTYWHDVMHDD
                     VFMVMNDGWLEAAKPRQIVVDKDRKLSETPDLVVGTGRSAEKYKMDLLPPNLIVERYFA
                     KERAEVDELISLSEEASRLVEEYVEEHAVEGGLLAEAMDDEKINKALASARLKKARHEG
                     TDADEVASLSHLINLYNAEAVAKKAAKEAEAALSLVTLKKYGELAESEIKQLTLNDKWQ
                     ATVTDRVAQVVESLTLTLVGRIKELGKRYAETVDAIKADLENIEAKVARHLSAMGVM"
     gene            3507..4649
                     /locus_tag="ASD48_RS21150"
                     /old_locus_tag="ASD48_12695"
     CDS             3507..4649
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013579.4"
                     /locus_tag="ASD48_RS21150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12695"
                     /product="restriction endonuclease subunit S"
                     /protein_id="WP_157880661.1"
                     /transl_table=11
                     /translation="MGNIARVNIDLSRIEYIPDSEAVSPLHRLRYGDVLFNTRNTLDLV
                     GKVSIWRDELPVAYYNSNILKLEFKSEYCGDSRYFGYALNSAESIEAIRNLATGTTSVA
                     AVYTRDLLKLEIPVPSKSEQCAIADTLEDVERLISSLVLLIAKKQAIKQGIMQRLLTRR
                     VRRSDLSEPREETRLRDLGMVYGGLTGKRKGDFGQGVAAFVTFLDVVNNVRLMTPELGR
                     VRVHESEPQHRVMRGDVLFNGSSETPEEVALAAVVDFDAGSNTYLNSFCFGYRIRRPDL
                     VDPTFLAYFFRSGVGRASVASLAQGATRYNIAKSKFLDLALALPCLEEQQGTVAVLNDS
                     EEEIEFLRARLAKAREIKRGMMQELLTGRTRLPVQGESSE"
     gene            4646..7738
                     /locus_tag="ASD48_RS21155"
                     /old_locus_tag="ASD48_12700"
     CDS             4646..7738
                     /EC_number="3.1.21.3"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0009035 - type I site-specific
                     deoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000701.1"
                     /locus_tag="ASD48_RS21155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12700"
                     /product="HsdR family type I site-specific
                     deoxyribonuclease"
                     /protein_id="WP_057603197.1"
                     /transl_table=11
                     /translation="MSDVGQVEREAQKRVVRLFKEQLSYRYLGNWEYRTGNSNIEFELL
                     EANLRARGYDSTLISKAIDHLKKAAALGGGRDLYEANRAVYELLRYGVKVKPGAGEQYE
                     TIWLIDWSDAQANDFVVVEEVTIVGKQTKRPDIVLYVNGLALVTLELKRSRVAVSEGIR
                     QSIGNQKPQFIRSFFSTVQLVLAGNDVEGLRYGVIDTPEKYWLQWKEPSDVEEPLDRAL
                     LQMCGKERLLELIHDFTVFDSGVRKACRHNQYFGVKAAQERIGRREGGIIWHTQGSGKS
                     LTMVWLAKWIREHQNDARVLLITDRTELDEQIEKVFNGVNEQIYRTSSGMDLLDTLNKS
                     TEWLICSLVHKFGSSADGKDGSEASNEFIKELKARIPKGFKAKGNLFVFVDEAHRTQSG
                     KMHDAMKDLLPGAMFIGFTGTPLLKTDKATSMEKFGSFIHTYKFDEAVEDGVVLDLCYE
                     ARSIDQHLTSPAQVDKWFEAKTRGMTDLSKAELKKRWGTIQKVVSSEPRAKQIVQDILL
                     DMESKPRLMDGRGNAMLVGESIYQACKFYELFCNAGFRGKCAIVTSYAPSPGDISKEDS
                     GAGQTEKLRQYDIYRKMLADHFGESEDAAMTKVDQFEQEVKRQFVEEPSRMRLLIVVDK
                     LLTGFDAPSATYLYIDKKMSDHGLFQAICRVNRLDGDDKEFGCVVDYRDLFNSLQDAIT
                     DYTSGALDGYEPQDIEGLLTDRIEKGREALDEALERIRALCEVVAQPRNTLQYQQYFCA
                     ADPGNAEQLKANEPKRVELYKAVAGVTRAFANLANDMEAAGYTSQEAQDIRAEIRHYTD
                     VRDEVKLGAGEDVDFKQYEAGMRFLLDTYIQADASETVSDFEDTGLVQLIVELGAGALD
                     KLPKGIKSSPEAVAETVANNMRKLIIEEHATNPKYFDKMSELLDAIIEKRRQGAIEYQD
                     YLAKLLETAAQLGRGESDDTYKYPAWANNGAKRALVDFFLPDERLAVEVDTAVLHSKPH
                     AWVGNPLRERKVRNALKRALPDDFDRLDELLELVKARHEYH"
     misc_feature    7631..7633
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7773..8453
                     /locus_tag="ASD48_RS21160"
                     /old_locus_tag="ASD48_12705"
     CDS             7773..8453
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000702.1"
                     /locus_tag="ASD48_RS21160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12705"
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="WP_242432668.1"
                     /transl_table=11
                     /translation="MVYKDIKNLHIGVYPPIGRVRVAAPQQLDDDQVRLAVIQRLPWIK
                     RQQDQLRSAERQSVREMVSGESHYVWGVRRRLKVIERPGRPHVEIDGDRMLLYVPSGTG
                     EERRRDLLDRWCREQLRQAIPALIERWETKLGVSVPWWGIRRMKTKWGSCNRETRRLWF
                     NSELAKKHPECLEYVVVHEMVHYLERGHGQRFAQLMDGFLPDWRSRRDGLNAAPLSDEL
                     WMGR"
     gene            8663..9085
                     /locus_tag="ASD48_RS45345"
     CDS             8663..9085
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024977.4"
                     /locus_tag="ASD48_RS45345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_242432669.1"
                     /transl_table=11
                     /translation="MAKLRLTVGRGHVEELARLRHPVGAIEELIWNSLDADAENVTVVL
                     ERNDFDGVDRVAVIDDGTGIAAEKCSDYFEQIGTSWKKRTQVSEVKKRVLHGKNGRGRV
                     RAFALGSEVRWTSVSGMQGDLPSCGHRVRPRLHGRV"
     gene            9072..10658
                     /locus_tag="ASD48_RS21165"
                     /old_locus_tag="ASD48_12710"
     CDS             9072..10658
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASD48_RS21165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ASD48_12710"
                     /product="histidine kinase"
                     /protein_id="WP_242432670.1"
                     /transl_table=11
                     /translation="MDEFDVSDPEPTTDATGTAFEAFGGEDLQKLTEDAARTALTAAFA
                     LHLEAYPDICITYDGTRLDPASEQVHVDTYEVAAPPGSSHPPAQLKIIEWSRPYSRALI
                     LCDGRGMSLAQLKPEIQAPGFHFTAYLSWSGFEDDSVGDLAFADWTPEGPAAEVLAEAR
                     ERMREHFRSRADERRRELVDQWRAEGFYPYMGEPANDQERAERETFDAVATAVVRHLPA
                     SKRAQKVSFALLRSVLTHEPGEVLRIAEELFALSKQEQTELSRLLDRTPLSALIKASTA
                     TTGRLDFLSALEHLVFEPVAKGRVKERTELHRILENECWIFGEEYGLHASDRSLNEVLR
                     QHCRLLGRDAPAPDPVLREDGRKSIVDLMLSRAARQRKGERHHLVVELKRSSVTLGMAE
                     FSQINSYAQAVMNDDRFRDPKVTWDFWLVGNAMEDGLRQLAHQPDRMPGCAVNQPTYRI
                     WVRTWGEIIEDAQERLRFYSEQLEYQSTTEHAMDYLIREHADAVVDLVSDGTVPVARTG
                     DSGSIGAATTP"
     gene            complement(11142..12101)
                     /locus_tag="ASD48_RS21170"
                     /old_locus_tag="ASD48_12715"
     CDS             complement(11142..12101)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010470222.1"
                     /locus_tag="ASD48_RS21170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12715"
                     /product="AAA family ATPase"
                     /protein_id="WP_057603200.1"
                     /transl_table=11
                     /translation="MGAIKDKGLQLHQIERVPYEEAFLIGDLLTTRITILSGEPKAGKT
                     LLAVGMSTALLNGDPTFLGLPVHKKLDHIVLGLTDDGAPAELKERMDGAVPYDSVTVFP
                     FSDTGDPWYWAGIYEDLARIKPGLFVLDNVIGALAPGEDIASSVTAQRLVNSLRPISDL
                     GIPTLLVTHTPKGTGEGMSVASSPIGGRAMGAAARGLIALRNSGKQGRRLQTANNRAIE
                     ELDIPVAVRRASPENEIPIWERIEPGLRAISRPKAGPWDEALIARVLEEQPQETTIKAL
                     ANKYAQDADRKPETLRPKLSAALTHVGGRWVRRTTEAA"
     gene            complement(12211..12375)
                     /locus_tag="ASD48_RS41340"
     CDS             complement(12211..12375)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009996368.1"
                     /locus_tag="ASD48_RS41340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_078883422.1"
                     /transl_table=11
                     /translation="MTVDELAEYLGKKPAWIYNNHRTLGIPSRKVGGSLRFRLSEVDRW
                     IDRECPVSA"
     misc_feature    12562..12577
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.91"
                     /tool="antismash"
     gene            12563..13081
                     /locus_tag="ASD48_RS21175"
                     /old_locus_tag="ASD48_12720"
     CDS             12563..13081
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASD48_RS21175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ASD48_12720"
                     /product="hypothetical protein"
                     /protein_id="WP_057603201.1"
                     /transl_table=11
                     /translation="MTVIKRTGAWVVTMYWPEGASGSVGPREVHVVPADDADPQEVARG
                     ISSTVLRRINTTPSRDFAAMRSLEKAADMDIRQLGKRLTSLPSGLTDERLAVLSALYVH
                     FVDAGERAPAQRLAVGFDLNPATVKGHLRAARQRGFLTKVEGKAGGQLTDKAVQTLRGM
                     KSGAGTEEV"
     gene            13056..14255
                     /locus_tag="ASD48_RS42165"
     CDS             13056..14255
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018851583.1"
                     /locus_tag="ASD48_RS42165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="site-specific integrase"
                     /protein_id="WP_079073884.1"
                     /transl_table=11
                     /translation="MAQVLKKCDCRNKTRCGHRWTVRYREPGGRSARQRERSFPTKKEA
                     ESFGVKAENDKRQGVYIDPQLGQISLRKWAEEWLEQHQVNESTRRNYQGFLSNHLIPEL
                     GSRTLAGLTVADVKKLQASMVGRGLTAATVNDRLNILRSMMTAAVKERRIPDSPCDEVP
                     PLKAAGAAVDPDEIPTLAEVYAIAAAMSEQYRLTVWLQAGAGLRISETLGFSVDCQRDG
                     FLRLRRQISAKANQGDCVTRFVPLKHRTAEEFRDVPTPTFLDQEIGLHLKRWGTVVLDG
                     LEVLFAPRERGKGKMPTASTYGYHWRKALKVAGVTTPDGKPKYTPHSLRHFFASTALAN
                     GVPIHEVSRWLGHRNIKTTVDTYGHLVPEAWDRCRDVMQEALRPSVPRQAAEPSTALAA
                     "
     gene            15001..18843
                     /locus_tag="ASD48_RS21185"
                     /old_locus_tag="ASD48_12730"
     CDS             15001..18843
                     /GO_function="GO:1904091 - non-ribosomal peptide synthetase
                     activity [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (10-384). E-value: 4e-74.
                     Score: 241.6. Matches aSDomain:
                     nrpspksdomains_ASD48_RS21185_AMP-binding.1"
                     /NRPS_PKS="Domain: PP-binding (502-564). E-value: 7.2e-14.
                     Score: 43.9. Matches aSDomain:
                     nrpspksdomains_ASD48_RS21185_PP-binding.1"
                     /NRPS_PKS="Domain: TIGR02353 (586-1272). E-value: 1.3e-203.
                     Score: 669.9. Matches aSDomain:
                     nrpspksdomains_ASD48_RS21185_TIGR02353.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     TIGR02353"
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565944.1"
                     /locus_tag="ASD48_RS21185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12730"
                     /product="Pls/PosA family non-ribosomal peptide synthetase"
                     /protein_id="WP_057603562.1"
                     /sec_met_domain="AMP-binding (E-value: 9.5e-76, bitscore:
                     250.9, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 7.6e-11, bitscore:
                     38.3, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR02353 (E-value: 2.2e-202, bitscore:
                     669.9, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPRTLLDILEASVRVYPDAPALDADGVVLSYRELWDRAGLLARD
                     LAVLGVGVGDRVGVRVPSGTVDLYTAVLTVLRAGAAYVPVDAEDPDRRAAVVWADAEVC
                     AVIGESGTVRPVPGRVPCGRAGQPRPADDAWIIFTSGTSGPPKGVAVTHRSAAAFVDAE
                     AQLFLRHRPPGPGDRVLAGLSVAFDASCEEMWLAWRHGACLVPAPRSLVRAGAELGPWL
                     LERGVTVVSTVPTLAALWPAECLTGVRLLVLGGEACPAELVDRLAAPQRELWNTYGPTE
                     TTVVACAARLVPGRPVRVGAPLAGCEVAVVGPDNEPVAWGEIGELVIGGVGTARYLDPA
                     KDAEKFQPHPVLRSVRAYRSGDLVRADPLGLVYVGRADEQVKLSGRRVELGEIDAALRS
                     LPGVSAAAAAVRATRAGGQVLVGYLVLHGDGRPCFDTAAARVLLLTRLPRPLVPLLAVV
                     DGLPTRASGKVDRDALPWPLLDQHATPGAGTAPGAAPGPTGTAGWLTDLWESLLGLRPE
                     EDSDFFALGGTSLSAAQLVSTLRERVPGVSVTDVYRCPRLTDLAARLDDLEVGGEPART
                     IRPTPRWTGAVQLVVVTVLCAVVGIRLLVLLAALDNLLGPRSWAPRSSWWLIAAGWLAL
                     SSAPGRVVIGAAVGRLLTAGFRPGTHPRGGSVHLRLWAAERMGTVLGTATLLGTHWAAR
                     YAKALGCAVGQSVDLHAMPPVTGMARFGSGCVLEPGADVAGWWLDGDVLHLGRVEIGDG
                     ARVGARSMLMPGAKVGSGADVAPGSCVEGEVPADERWHGSPARRMSGAPRAGHDWPQPV
                     RRRSRRWELAYSAALSALGLLPLVASLPALLVLNRLVGDEHGLGAVVLDLLLLTPLLVL
                     LAMGCYAALTVVLVRLAGRVLTPGHHPTCGRVTWCAWWVARLMSMARTSLFPFYAGLLT
                     PLWLRLLGARVGRQAEVSTVLGLPALMRVGDQAFLADDTLVAPFELRGGWLRLDFSRVG
                     RRAFVGNSGIVGPGRELPPGALVGVLSDAPAHAEPGSSWLGRPGLSLPRVREKGDPGRT
                     WAPPRRLVLARAAVEACRLVPIMGTAFIGSLAAVALQVLAARHGLLVAAALSGVVLLGA
                     GVLACLATTAAKWLVVGRFRTGRHPLWSSFVWRNELYDTFVEELAIPWLGRLLTGTPFL
                     NLWLRSLGARIGRGVWCETHWLPETDLVRIGDGASVNRGCVVQTHVFHDRVLQLDQIRL
                     DAGATLGPHSIALPGASLAAGTVVGPASLVMRGERVPARTRWLGNPIAPSTPASS"
     aSDomain        15031..16152
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS21185_AMP-binding.1"
                     /evalue="4.00E-74"
                     /label="ASD48_RS21185_AMP-binding.1"
                     /locus_tag="ASD48_RS21185"
                     /protein_end="384"
                     /protein_start="10"
                     /score="241.6"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="EASVRVYPDAPALDADGVVLSYRELWDRAGLLARDLAVLGVGVGD
                     RVGVRVPSGTVDLYTAVLTVLRAGAAYVPVDAEDPDRRAAVVWADAEVCAVIGESGTVR
                     PVPGRVPCGRAGQPRPADDAWIIFTSGTSGPPKGVAVTHRSAAAFVDAEAQLFLRHRPP
                     GPGDRVLAGLSVAFDASCEEMWLAWRHGACLVPAPRSLVRAGAELGPWLLERGVTVVST
                     VPTLAALWPAECLTGVRLLVLGGEACPAELVDRLAAPQRELWNTYGPTETTVVACAARL
                     VPGRPVRVGAPLAGCEVAVVGPDNEPVAWGEIGELVIGGVGTARYLDPAKDAEKFQPHP
                     VLRSVRAYRSGDLVRADPLGLVYVGRADEQVKLS"
     aSModule        15031..18816
                     /complete
                     /domains="nrpspksdomains_ASD48_RS21185_AMP-binding.1"
                     /domains="nrpspksdomains_ASD48_RS21185_PP-binding.1"
                     /domains="nrpspksdomains_ASD48_RS21185_TIGR02353.1"
                     /locus_tags="ASD48_RS21185"
                     /monomer_pairings="X -> X"
                     /starter_module
                     /tool="antismash"
                     /type="nrps"
     CDS_motif       15223..15258
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21185_0001"
                     /evalue="3.90E-04"
                     /label="NRPS-A_a2"
                     /locus_tag="ASD48_RS21185"
                     /protein_end="86"
                     /protein_start="74"
                     /score="13.9"
                     /tool="antismash"
                     /translation="VLRAGAAYVPVD"
     CDS_motif       15400..15459
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21185_0002"
                     /evalue="1.20E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="ASD48_RS21185"
                     /protein_end="153"
                     /protein_start="133"
                     /score="24.0"
                     /tool="antismash"
                     /translation="AWIIFTSGTSGPPKGVAVTH"
     CDS_motif       15592..15618
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21185_0003"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a2"
                     /locus_tag="ASD48_RS21185"
                     /protein_end="206"
                     /protein_start="197"
                     /score="-3.1"
                     /tool="antismash"
                     /translation="WRHGACLVP"
     CDS_motif       15961..16038
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21185_0004"
                     /evalue="9.50E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="ASD48_RS21185"
                     /protein_end="346"
                     /protein_start="320"
                     /score="14.8"
                     /tool="antismash"
                     /translation="GEIGELVIGGVGTARYLDPAKDAEKF"
     CDS_motif       16117..16179
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21185_0005"
                     /evalue="1.30E-09"
                     /label="NRPS-A_a8"
                     /locus_tag="ASD48_RS21185"
                     /protein_end="393"
                     /protein_start="372"
                     /score="30.2"
                     /tool="antismash"
                     /translation="YVGRADEQVKLSGRRVELGEI"
     aSDomain        16507..16692
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS21185_PP-binding.1"
                     /evalue="7.20E-14"
                     /label="ASD48_RS21185_PP-binding.1"
                     /locus_tag="ASD48_RS21185"
                     /protein_end="564"
                     /protein_start="502"
                     /score="43.9"
                     /tool="antismash"
                     /translation="WLTDLWESLLGLRPEEDSDFFALGGTSLSAAQLVSTLRERVPGVS
                     VTDVYRCPRLTDLAARL"
     aSDomain        16759..18816
                     /aSDomain="TIGR02353"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS21185_TIGR02353.1"
                     /evalue="1.30E-203"
                     /label="ASD48_RS21185_TIGR02353.1"
                     /locus_tag="ASD48_RS21185"
                     /protein_end="1272"
                     /protein_start="586"
                     /score="669.9"
                     /tool="antismash"
                     /translation="VQLVVVTVLCAVVGIRLLVLLAALDNLLGPRSWAPRSSWWLIAAG
                     WLALSSAPGRVVIGAAVGRLLTAGFRPGTHPRGGSVHLRLWAAERMGTVLGTATLLGTH
                     WAARYAKALGCAVGQSVDLHAMPPVTGMARFGSGCVLEPGADVAGWWLDGDVLHLGRVE
                     IGDGARVGARSMLMPGAKVGSGADVAPGSCVEGEVPADERWHGSPARRMSGAPRAGHDW
                     PQPVRRRSRRWELAYSAALSALGLLPLVASLPALLVLNRLVGDEHGLGAVVLDLLLLTP
                     LLVLLAMGCYAALTVVLVRLAGRVLTPGHHPTCGRVTWCAWWVARLMSMARTSLFPFYA
                     GLLTPLWLRLLGARVGRQAEVSTVLGLPALMRVGDQAFLADDTLVAPFELRGGWLRLDF
                     SRVGRRAFVGNSGIVGPGRELPPGALVGVLSDAPAHAEPGSSWLGRPGLSLPRVREKGD
                     PGRTWAPPRRLVLARAAVEACRLVPIMGTAFIGSLAAVALQVLAARHGLLVAAALSGVV
                     LLGAGVLACLATTAAKWLVVGRFRTGRHPLWSSFVWRNELYDTFVEELAIPWLGRLLTG
                     TPFLNLWLRSLGARIGRGVWCETHWLPETDLVRIGDGASVNRGCVVQTHVFHDRVLQLD
                     QIRLDAGATLGPHSIALPGASLAAGTVVGPASLVMRGERVPARTRWLGNPI"
     gene            19016..>19204
                     /locus_tag="ASD48_RS21190"
                     /pseudo=""
     CDS             19016..>19204
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030030.1"
                     /locus_tag="ASD48_RS21190"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MRGGGRGAGSVGRGERDMVARGARLSEAARAVVGDHARAVEAVRA
                     ALKPLHDAAVQRELEAIP"
     misc_feature    19222..19233
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            19462..20421
                     /locus_tag="ASD48_RS21195"
                     /old_locus_tag="ASD48_12735"
     CDS             19462..20421
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127998.1"
                     /locus_tag="ASD48_RS21195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12735"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_057603205.1"
                     /transl_table=11
                     /translation="MTETQLRPASGEVTSPDAAVLSAVVKRFANAKGEEFTAVDGLDLR
                     IRRGEVVAFLGPNGAGKTTTIDMLLGLTRPDAGQVELFGEAAQQAVRAGRVAAVLQSGG
                     LLPDLTVEATVRMLGSLHPGADPETVMSRAGVTRLRDRRVSECSGGEQQRLRFAIALLS
                     NPEFLVLDEPTAGMDVAARREFWATVREDARHGMTVLFATHYMEEADRFADRVVMVDRG
                     RVVADGSASSIRTRISGRTVSALISPQDAAAVADSASVRSVAVRGDRHYFDSTDSDALL
                     RLLVTRTSATEIEVAPRSLEEAFMAITQHGRTGQEVPR"
     gene            20418..21212
                     /locus_tag="ASD48_RS21200"
                     /old_locus_tag="ASD48_12740"
     CDS             20418..21212
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127997.1"
                     /locus_tag="ASD48_RS21200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12740"
                     /product="ABC transporter permease"
                     /protein_id="WP_057603207.1"
                     /transl_table=11
                     /translation="MTTLTAPPARPRASSFSGVNPTFVRYELARRFNRQTTIFTLLLPA
                     VLYLALFRTAPAHGTLPHGNFAAWMMIGLAVYGAAMAATSSAATISVEKSAGWMRTIAL
                     SPLAPPGYLLVKVLCSVVMAAVPVAIVGVLGFVTGAHADAEVWVTSLVVAWLGAAVFAA
                     LGISLGLALKPDVVMHMPGLTMTALAFLGNLFIPLSGTMLEISRYTPMYGVSTLARYAL
                     TDGYSFSGEHSSLAGAVFNIVAWFAGFGFMAVRRFAKSTGRQ"
     misc_feature    21395..21410
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.96"
                     /tool="antismash"
     misc_feature    complement(21396..21409)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.83"
                     /tool="antismash"
     gene            21403..22341
                     /locus_tag="ASD48_RS21205"
                     /old_locus_tag="ASD48_12745"
     CDS             21403..22341
                     /EC_number="2.3.1.39"
                     /GO_function="GO:0004314 - [acyl-carrier-protein]
                     S-malonyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_AT (6-279). E-value: 1.6e-42. Score:
                     137.8. Matches aSDomain:
                     nrpspksdomains_ASD48_RS21205_PKS_AT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1021: malonyl CoA-acyl carrier protein transacylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127996.1"
                     /locus_tag="ASD48_RS21205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12745"
                     /product="ACP S-malonyltransferase"
                     /protein_id="WP_057603209.1"
                     /sec_met_domain="PKS_AT (E-value: 2.7e-41, bitscore: 137.8,
                     seeds: 1682, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFAIMAPGQGSQTPGMMAGWLRDPVHAERVRAWSEAADCDLVHLG
                     TRASAAEIARTENTQPLLVAQGLLAHEALAAAGAAVAAGHSVGELTAAAYAGVLTPVDA
                     VRLAAVRGRAMAAACAEAPTSMAAVVGGDEARVLERIAELGLYAATFNGPGQIVAAGLT
                     ERLQQLAAAPPHGSTVKPLPVAGAFHTPYMESARQAFAAAAATTDFTAPRGALLSNADG
                     EVVADPETVRRRLVDQVVRPVRWDLCLHTLARLAPGLTVSLPPARTLANILKRRHPELD
                     VLPVSTARDIGKALVRIGESARKEEPAHAGV"
     CDS_motif       21421..21456
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21205_0001"
                     /evalue="1.80E-03"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="ASD48_RS21205"
                     /protein_end="18"
                     /protein_start="6"
                     /score="11.4"
                     /tool="antismash"
                     /translation="PGQGSQTPGMMA"
     aSDomain        21421..22239
                     /ASF="(Methyl)Malonyl-CoA specificity inconclusive"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS21205_PKS_AT.1"
                     /evalue="1.60E-42"
                     /label="ASD48_RS21205_PKS_AT.1"
                     /locus_tag="ASD48_RS21205"
                     /protein_end="279"
                     /protein_start="6"
                     /score="137.8"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="PGQGSQTPGMMAGWLRDPVHAERVRAWSEAADCDLVHLGTRASAA
                     EIARTENTQPLLVAQGLLAHEALAAAGAAVAAGHSVGELTAAAYAGVLTPVDAVRLAAV
                     RGRAMAAACAEAPTSMAAVVGGDEARVLERIAELGLYAATFNGPGQIVAAGLTERLQQL
                     AAAPPHGSTVKPLPVAGAFHTPYMESARQAFAAAAATTDFTAPRGALLSNADGEVVADP
                     ETVRRRLVDQVVRPVRWDLCLHTLARLAPGLTVSLPPARTLANILKRRHPE"
     CDS_motif       21643..21750
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21205_0002"
                     /evalue="1.30E-13"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="ASD48_RS21205"
                     /protein_end="116"
                     /protein_start="80"
                     /score="42.9"
                     /tool="antismash"
                     /translation="VAAGHSVGELTAAAYAGVLTPVDAVRLAAVRGRAMA"
     gene            22328..23857
                     /locus_tag="ASD48_RS21210"
                     /old_locus_tag="ASD48_12750"
     CDS             22328..23857
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (6-395). E-value: 4.3e-92.
                     Score: 300.8. Matches aSDomain:
                     nrpspksdomains_ASD48_RS21210_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) NAPAA:
                     AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127995.1"
                     /locus_tag="ASD48_RS21210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12750"
                     /product="class I adenylate-forming enzyme family protein"
                     /protein_id="WP_057603211.1"
                     /sec_met_domain="AMP-binding (E-value: 2.1e-90, bitscore:
                     299.2, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVSDLFERARAERPDHPAVVDGDGTLTYAELGADVDRAAGWLRA
                     QGVAPGQRVVHAGGNDRTFLALFHATLRIGAVFVPVHPDLTDLQIGGIVEDCSAALAIC
                     PPGAGERAGRTVPVGQARQEIRDAPADGFAARIPDDGVAMLIYTSGTTGRPKGVVCPHR
                     QMIAAVEAVGACLGYTADDVVLCRLPLSFDYGLYQALLCARTGGTLVLAERGGDRGLLQ
                     TIEQHGVTVVPLVPSLAQMLALLQSRLRRPTGVRLFTNTGARPGRAVMAELLDVFPGSA
                     FASMYGMTECKRISILDPAEYAAHPDSVGRPIPGDRVRIVDGRKRELGPREVGEIVVAG
                     TTVMAGYWGVPLEAQHRYVRDADGALELHTGDQGYLDEDGRLYFVGRDDDMIKRRGIRL
                     GLTEIEDAAERIPGVIAAVALRPETEDAPLLLAVQTSLTPEEIRDRLRQRLDRARLPDL
                     IVPLDAVPLTANGKPDRKAAGLLVRAAAHRPAGQTTRQPAQTRTSHEPVAV"
     aSDomain        22346..23512
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS21210_AMP-binding.1"
                     /evalue="4.30E-92"
                     /label="ASD48_RS21210_AMP-binding.1"
                     /locus_tag="ASD48_RS21210"
                     /protein_end="395"
                     /protein_start="6"
                     /score="300.8"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FERARAERPDHPAVVDGDGTLTYAELGADVDRAAGWLRAQGVAPG
                     QRVVHAGGNDRTFLALFHATLRIGAVFVPVHPDLTDLQIGGIVEDCSAALAICPPGAGE
                     RAGRTVPVGQARQEIRDAPADGFAARIPDDGVAMLIYTSGTTGRPKGVVCPHRQMIAAV
                     EAVGACLGYTADDVVLCRLPLSFDYGLYQALLCARTGGTLVLAERGGDRGLLQTIEQHG
                     VTVVPLVPSLAQMLALLQSRLRRPTGVRLFTNTGARPGRAVMAELLDVFPGSAFASMYG
                     MTECKRISILDPAEYAAHPDSVGRPIPGDRVRIVDGRKRELGPREVGEIVVAGTTVMAG
                     YWGVPLEAQHRYVRDADGALELHTGDQGYLDEDGRLYFVGRDDDMIKRR"
     CDS_motif       22754..22813
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21210_0001"
                     /evalue="4.80E-09"
                     /label="NRPS-A_a3"
                     /locus_tag="ASD48_RS21210"
                     /protein_end="162"
                     /protein_start="142"
                     /score="28.3"
                     /tool="antismash"
                     /translation="AMLIYTSGTTGRPKGVVCPH"
     CDS_motif       23276..23323
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21210_0002"
                     /evalue="3.80E+01"
                     /label="NRPS-A_a8"
                     /locus_tag="ASD48_RS21210"
                     /protein_end="332"
                     /protein_start="316"
                     /score="-2.3"
                     /tool="antismash"
                     /translation="RVRIVDGRKRELGPRE"
     CDS_motif       23321..23374
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21210_0003"
                     /evalue="8.00E-05"
                     /label="NRPS-A_a6"
                     /locus_tag="ASD48_RS21210"
                     /protein_end="349"
                     /protein_start="331"
                     /score="15.1"
                     /tool="antismash"
                     /translation="EVGEIVVAGTTVMAGYWG"
     CDS_motif       23477..23542
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21210_0004"
                     /evalue="1.10E-05"
                     /label="NRPS-A_a8"
                     /locus_tag="ASD48_RS21210"
                     /protein_end="405"
                     /protein_start="383"
                     /score="18.1"
                     /tool="antismash"
                     /translation="FVGRDDDMIKRRGIRLGLTEIE"
     gene            23838..24092
                     /locus_tag="ASD48_RS21215"
                     /old_locus_tag="ASD48_12755"
     CDS             23838..24092
                     /NRPS_PKS="Domain: PP-binding (7-56). E-value: 1.7e-14.
                     Score: 45.8. Matches aSDomain:
                     nrpspksdomains_ASD48_RS21215_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127994.1"
                     /locus_tag="ASD48_RS21215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12755"
                     /product="acyl carrier protein"
                     /protein_id="WP_057603213.1"
                     /sec_met_domain="PP-binding (E-value: 1.5e-11, bitscore:
                     40.6, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNQSQFDQLVEEICAVTVTDPQTPLVDLGVDSLQTIALVMAVEEQ
                     YGIEIDPEVLADPALTSSAGLLASVQDQLAAALPARAGS"
     aSDomain        23859..24005
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS21215_PP-binding.1"
                     /evalue="1.70E-14"
                     /label="ASD48_RS21215_PP-binding.1"
                     /locus_tag="ASD48_RS21215"
                     /protein_end="56"
                     /protein_start="7"
                     /score="45.8"
                     /tool="antismash"
                     /translation="QLVEEICAVTVTDPQTPLVDLGVDSLQTIALVMAVEEQYGIEIDP
                     EVLA"
     gene            24098..25288
                     /locus_tag="ASD48_RS21220"
                     /old_locus_tag="ASD48_12760"
     CDS             24098..25288
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (36-382). E-value:
                     8.7e-39. Score: 125.6. Matches aSDomain:
                     nrpspksdomains_ASD48_RS21220_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127993.1"
                     /locus_tag="ASD48_RS21220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12760"
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_057603215.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.7e-37, bitscore:
                     125.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWTDTRPAVEMPRLFERGGDLISFAGGLPDLDVLPLDVLSAQLSR
                     LLRLGGKLALQYTTPHVAGALVPAITDLMAREGGRTTAENLVPTGGSQMGLMAVALGLA
                     APGETVLCQTPAYPGAAAAFRTAGLHPHAVPEDAEGLDPEGLRETVRRLRADGRTARLL
                     YCNPTFQNPTGATLSVARRRELLTVARELDLLIVEDNPYGLLGFDGRTTDTLQGLDPDR
                     VIYLGTFSKVFAPGLRCGWIAAPAELASTLRRTTEIMALSPSALAQAALAAFHTRSGWT
                     DLIDAYRASYRERSTLMADALDAELGADGPWSWQRPDGGFYIWLRHRNGVDTNTFADAA
                     AEHGVSFVPGSHFGIGGENADALRLCFSHVPKKRIPEGISRLAAALGRRAAEGAAA"
     aSDomain        24206..25243
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS21220_Aminotran_1_2.1"
                     /evalue="8.70E-39"
                     /label="ASD48_RS21220_Aminotran_1_2.1"
                     /locus_tag="ASD48_RS21220"
                     /protein_end="382"
                     /protein_start="36"
                     /score="125.6"
                     /tool="antismash"
                     /translation="DVLSAQLSRLLRLGGKLALQYTTPHVAGALVPAITDLMAREGGRT
                     TAENLVPTGGSQMGLMAVALGLAAPGETVLCQTPAYPGAAAAFRTAGLHPHAVPEDAEG
                     LDPEGLRETVRRLRADGRTARLLYCNPTFQNPTGATLSVARRRELLTVARELDLLIVED
                     NPYGLLGFDGRTTDTLQGLDPDRVIYLGTFSKVFAPGLRCGWIAAPAELASTLRRTTEI
                     MALSPSALAQAALAAFHTRSGWTDLIDAYRASYRERSTLMADALDAELGADGPWSWQRP
                     DGGFYIWLRHRNGVDTNTFADAAAEHGVSFVPGSHFGIGGENADALRLCFSHVPKKRIP
                     EGISRL"
     gene            25285..27615
                     /locus_tag="ASD48_RS21225"
                     /old_locus_tag="ASD48_12765"
     CDS             25285..27615
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lant_dehydr_N"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127992.1"
                     /locus_tag="ASD48_RS21225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12765"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_057603218.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.1e-24, bitscore:
                     81.0, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTLEATRALDWTAFGPSYRLGDSAWRVWGVGLLRSAGFPVSGL
                     GLIGGPHAARAAAQLLETGGGTDGREAFSAAYRADTDAEAGRLALLATDDKVRTAIAWQ
                     NRTVYQILDSLAARKGKESKRRQRERTLAMYWLRYCAKADTIGFFGPGAWISVGRGQRA
                     VDLDLGPSLTSRSRTFLERWTVAALADWMAGQPGARWWFPPMLRPDVHLDGDRLVMQGG
                     RTVRLREDDVRVLRLVDGDRGGEAIAEATGWEPATARERVEKVLTRLLRQRVLTWDANI
                     PVDVRAEEVLRRRVAGIGDPELFVRFDAVLSGLDRLRDGIDRASSAEELVAALDRLDEF
                     FVRTTGQSASRDEGKAYAGRTLCYQDSLRDCRMDLGRDFLDGIARPLALVADAADWFGN
                     RLAELVEAEVAGFVRKAAARRRGDVTLADVWTQVLGLFWGDHATPVETATRELAEKWRE
                     VLHLAEEQRAPVRLSVSDIEKRAREVFATGPVRSPHLAVHSPDLQVVARSVDAFNAGDY
                     TTVLGELHACLATLDLPFLDWTTDAGSLRDKVNAAIGARRLVPLLPVEWKRNSGRMVPA
                     PIGAGDRLIGFTRAPYDDRTRVDPAVSVGLAEKDGTVTATTPDGGVWSIAELLAVPVAI
                     IAADAFKIGLDRPHAPRVSLDDLVLFRETWRLPAAGTELPDKAERERDYLAVRRWVAEH
                     ALPDLLFVKFPEETKPSLVDFTSPTLVLSFANLVRAARRLDPDAVITLSEPLPAPEDSW
                     LPDADGERFVSELRLQISRKVPE"
     gene            27612..28700
                     /gene="sbnA"
                     /locus_tag="ASD48_RS21230"
                     /old_locus_tag="ASD48_12770"
     CDS             27612..28700
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1081: cysteine synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127991.1"
                     /locus_tag="ASD48_RS21230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12770"
                     /product="2,3-diaminopropionate biosynthesis protein SbnA"
                     /protein_id="WP_057603220.1"
                     /sec_met_domain="PALP (E-value: 1.1e-58, bitscore: 194.9,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVLASDGAALAVRATRTRDPDIVATIGGTPLVALDRLFPPARFQ
                     VYAKCERFNPGGSIKDRAAKSMIEHAIRAGKLVPGVSTVVESSSGNLGIALAQLCNFYR
                     LNLICVIDPRTTPQNAAIMRAYGARVEVVDRDPATGEYLPARIERVRSLLESVPDAYWP
                     NQYANEHNSRAHHHTMREIHEALPGGPDHLFLAAGTTGTLRGCAEYIRDHGLATNVVAV
                     DAVGSVIFGPPEPWELTHRRTIPGHGAAVVPPLLRPGLADRIVKVTDLDCVRGCRQLLA
                     QESILAGGSSGAVVAALQHAASWIEPGATCVAVLPDGGDRYLDTVYSDSWVEDRFKDFP
                     LPDHTRLDHPGPDTTDHERSES"
     gene            28697..29725
                     /gene="sbnB"
                     /locus_tag="ASD48_RS21235"
                     /old_locus_tag="ASD48_12775"
     CDS             28697..29725
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sbnB"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1158: ornithine cyclodeaminase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127990.1"
                     /locus_tag="ASD48_RS21235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12775"
                     /product="2,3-diaminopropionate biosynthesis protein SbnB"
                     /protein_id="WP_057603221.1"
                     /transl_table=11
                     /translation="MRILGRDDVAVALKGLGPAVLDAVRSAYVLHGQGHSQVPFSSFLR
                     PPRPAGSRIISLPAYLGGPEPVMGLKWISSFPANVEQGLQRASSVQVLNDLDTGYPQAL
                     LEGSQISSSRTAASAALASGALHGSRPVRTAGFIGCGTINQRVLAFLTLTHPELETVVL
                     QDVVPGRAEVFAAELECEYPGITFRTGDIAEALGAETVSIATTDSTYWLDLAAHPDRPS
                     RQVILHLSLRDLSTDSVLGAYNVVDDIEHAVRERTSLHRAEQETGHREFVHAEIAGVLG
                     CSEPPATDRTIVFSPFGLGILDLAVAQAVLKAATAAGLGTEAAGFDPGSHRVTAAMAGR
                     AA"
     gene            29722..30474
                     /gene="fabG"
                     /locus_tag="ASD48_RS21240"
                     /old_locus_tag="ASD48_12780"
     CDS             29722..30474
                     /EC_number="1.1.1.100"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (11-170). E-value: 1.1e-18.
                     Score: 59.8. Matches aSDomain:
                     nrpspksdomains_ASD48_RS21240_PKS_KR.1"
                     /codon_start=1
                     /gene="fabG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018554086.1"
                     /locus_tag="ASD48_RS21240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12780"
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="WP_057603222.1"
                     /sec_met_domain="adh_short (E-value: 1.9e-39, bitscore:
                     131.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 2.5e-31, bitscore:
                     105.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTFFAEGTKALVTGASRGIGAAIALTLAEHGCDVALNYRSNEAK
                     AEEVAERIRALGREALPVRADVSDEAQVAAMYKQLKAAWGRLDVAVLNSGVTADGHLAA
                     MSSAKWQEVIGTNLTGTFYTAREATKQMYASGGAIVFIASTSGIAGRAGQANYAASKGG
                     VIAMAKTLSYEVAPRGIRVNVVAPGFIDTDMVKKVPPAHMKEALQVIPMGRMGTAAEVA
                     QAAAFLAAPAASYITGKVLTVDGGMIPN"
     CDS_motif       29755..29820
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21240_0001"
                     /evalue="2.20E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ASD48_RS21240"
                     /protein_end="33"
                     /protein_start="11"
                     /score="17.1"
                     /tool="antismash"
                     /translation="LVTGASRGIGAAIALTLAEHGC"
     aSDomain        29755..30231
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS21240_PKS_KR.1"
                     /evalue="1.10E-18"
                     /label="ASD48_RS21240_PKS_KR.1"
                     /locus_tag="ASD48_RS21240"
                     /protein_end="170"
                     /protein_start="11"
                     /score="59.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="LVTGASRGIGAAIALTLAEHGCDVALNYRSNEAKAEEVAERIRAL
                     GREALPVRADVSDEAQVAAMYKQLKAAWGRLDVAVLNSGVTADGHLAAMSSAKWQEVIG
                     TNLTGTFYTAREATKQMYASGGAIVFIASTSGIAGRAGQANYAASKGGVIAMAKT"
     CDS_motif       30139..30198
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS21240_0002"
                     /evalue="4.80E-06"
                     /label="PKSI-KR_m4"
                     /locus_tag="ASD48_RS21240"
                     /protein_end="159"
                     /protein_start="139"
                     /score="19.1"
                     /tool="antismash"
                     /translation="VFIASTSGIAGRAGQANYAA"
     gene            30547..30837
                     /locus_tag="ASD48_RS21245"
                     /old_locus_tag="ASD48_12785"
     CDS             30547..30837
                     /NRPS_PKS="Domain: PP-binding (21-91). E-value: 1.3e-12.
                     Score: 39.8. Matches aSDomain:
                     nrpspksdomains_ASD48_RS21245_PP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014137325.1"
                     /locus_tag="ASD48_RS21245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12785"
                     /product="phosphopantetheine-binding protein"
                     /protein_id="WP_020127988.1"
                     /sec_met_domain="PP-binding (E-value: 2.8e-10, bitscore:
                     36.5, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding_2 (E-value: 3.3e-05, bitscore:
                     20.0, seeds: 2, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVATFEDIRTQAETRLAKNMKVKSMIIDRLGLDVEPAVVSDNQP
                     LFGRGLEMDSLDTLEIVVMVNNEYDVLISDDDFEAFGSINALVDFIEAREV"
     aSDomain        30610..30819
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS21245_PP-binding.1"
                     /evalue="1.30E-12"
                     /label="ASD48_RS21245_PP-binding.1"
                     /locus_tag="ASD48_RS21245"
                     /protein_end="91"
                     /protein_start="21"
                     /score="39.8"
                     /tool="antismash"
                     /translation="KVKSMIIDRLGLDVEPAVVSDNQPLFGRGLEMDSLDTLEIVVMVN
                     NEYDVLISDDDFEAFGSINALVDFI"
     gene            30840..31364
                     /gene="fabZ"
                     /locus_tag="ASD48_RS21250"
                     /old_locus_tag="ASD48_12790"
     CDS             30840..31364
                     /EC_number="4.2.1.59"
                     /codon_start=1
                     /gene="fabZ"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1270: UDP-3-O-[3-hydroxymyristoyl]
                     N-acetylglucosamine"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127987.1"
                     /locus_tag="ASD48_RS21250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12790"
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="WP_057603223.1"
                     /transl_table=11
                     /translation="MTIASEAPARPQQKHSYSSDDIKRMLPHRWPMLMIDRAYDVVPGV
                     SGRGVKSVSVNEPFFAGHYPDHSIMPGVMIVEAMAQLVAVVYVAELVEAAAAAAAAGAP
                     EGGDPSESVGYLGSISSMKFSRLVVPGDQLTLDAKLGQRLGGLRQVSVRASVGSELAAA
                     GSLIVTTGRKA"
     gene            31416..33569
                     /locus_tag="ASD48_RS21255"
                     /old_locus_tag="ASD48_12795"
     CDS             31416..33569
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127986.1"
                     /locus_tag="ASD48_RS21255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12795"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_057603224.1"
                     /transl_table=11
                     /translation="MSITIRPYQEGDAHDIAALYNRHRDNPNPVAGGITGDELERELAE
                     RDTGTFLVAVDGGRVVGTFGLFHNTGRRSARAGELIADMFFVAPAYRNGVITGRLFTEA
                     VEWMVQSGCLVLRLTVNPANSVAFKLYRRVGCVSVGQTVPGEDGNVELHNYIPLVLRSV
                     FADLGPEVRSALGGLNSFGTVTEARDDELRSDVRLVDGVRTVDYQLALGGFRITASVDV
                     DRGVVREAEVTGPDGTARALRLTEPPYHVRAPRRPEPHRFGSGGLVCEVDGDDGTLSVL
                     AEGHHGPLFVSTWPSCRADRPAGWREGEPRDLDIVAVENGVRVTERCGEDEVVGTVTLT
                     EGTLRQDFTFTSRPGRIFQTVGLRQGTFVHPDGERHPIGLGLGVRDASEAVAASQVVPA
                     GTELAWRSTSWGIGLPVREPVRLIHSALLERGLAAGPDGVARLRTDFHPATARTDAGTD
                     TTADAGTDTTTDAATEAATEAAADAATEPVTEAGTEAKTEAERPARTVPKPGAVRRLEL
                     TASAAGVTSWKEGTTKVLRSPYPRTRVFGYNPRWSAGMWVTAESSRFGRASGLGWGVRS
                     AAWEEKHPLGLFAPRERIGWELTAPENTAEPVRADIQAPDSEEEIVLWLTPNTPRETTV
                     LLDSAGTRWELGSAGFRQVWATAATVRLADGSWLDCRPADGACPQAELVLRTTPSGLLI
                     GCVSPARRPSAWQLAVHDGPTRS"
     gene            33621..34664
                     /locus_tag="ASD48_RS21260"
                     /old_locus_tag="ASD48_12800"
     CDS             33621..34664
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127985.1"
                     /locus_tag="ASD48_RS21260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12800"
                     /product="aminomethyltransferase family protein"
                     /protein_id="WP_057603225.1"
                     /transl_table=11
                     /translation="MTTTTVSAARTASDDYATVRTTIGAYRIDAPLVRVSGDERLALLD
                     QFLAKSGDFVEPDSVREVLALNADGTPFAILLHFEIGEDAWLLPRTRVTADELRGYLDG
                     LDVPEGVEVDIEPEGWAATAFEGPTAWSVAARFVDFDISGLTLHAVTESALPDDPAALA
                     HLARVGTTGEYGYLLLSNAPEAAHRAVLAAVQEEGGAPVGAEGLARVQAEAGMAVYAAG
                     FAGLSVDEADLSWMIDWNRIGEFRGSDDLVRPTAETARLTALAAPADSRFTAGTQVTAA
                     GREIGTVLWQAPSANPEEELVFALLDAPFWVSGLELAAPDEQAAERPLRTVTLPRVIAR
                     SLTTRIA"
     gene            34664..36982
                     /locus_tag="ASD48_RS21265"
                     /old_locus_tag="ASD48_12805"
     CDS             34664..36982
                     /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (71-390). E-value:
                     6.8e-48. Score: 155.5. Matches aSDomain:
                     nrpspksdomains_ASD48_RS21265_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (461-740). E-value:
                     1.6e-12. Score: 39.0. Matches aSDomain:
                     nrpspksdomains_ASD48_RS21265_PKS_KS.2"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) t2fas"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127984.1"
                     /locus_tag="ASD48_RS21265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12805"
                     /product="beta-ketoacyl-[acyl-carrier-protein] synthase
                     family protein"
                     /protein_id="WP_057603226.1"
                     /sec_met_domain="t2fas (E-value: 4e-92, bitscore: 305.0,
                     seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.2e-29, bitscore:
                     99.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPRIALTGLGLITGAGDDVEKGWSSIASGTSGIRTNTLMDTSE
                     LLTEWAGMVTGEQPADVDRCYALAATAIREALESSGLDLDTVDRDRVAVVVGSSLGAMP
                     TLESVHADLVHEGKLDAERAAAVQLPCVGDYIAAEFDLRGPRVVLSNACAASAVALGYA
                     AELLWKGDVDHVICGGVDPLASLSAYGFSALGALDPEPCSPMSASTGLTLGEGAGFMVL
                     ESADRAASRGARVLAELGGYGLSCDGYHQTAPDPSGKGACAAMAQALDTAGLTPQDVDY
                     LNLHGTGTPANDASEPKAVKLLFGSSVPPASSTKSILGHTLGAAGAVEAVVSTLAIDRG
                     TLPPTVNTRGVAQPFGLDVIPDTGRAGTRPEVVISNSFAFGGNNASVVLNRPGRPSSAP
                     RRTEQVHEVVVTGVAGLAGGAGNTADLVAALDGERACFTATEHVRGVGEVPVGRVDVKS
                     ASRGINPSRARRMDPLSLLAAAAVADLYGRHGKPSRAEAEGTGIVFATGYGPVTSVLQF
                     HKGVLQQGISGANPALFANTVVNAAAGHVAMLHRYRGYTATIANGGTSSVLALQLAARV
                     IARGMADRIMVVIADEFPEQALATQAGLPGYARSGPVVPGGRSGMVLSEGAAAVLLESE
                     RSASSRGADVLAKVRGYGASGEPAGIGRIGRDGEAWARALRGAMAEARVTPDEIDTVVS
                     AASGYSLVDTAQSRALRLAGLLDRPTITPKALLGETYGSAGALGLVAALTAPTRQGRLL
                     LSSFAYGGSYAAAVFDTEA"
     aSDomain        34877..35833
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS21265_PKS_KS.1"
                     /domain_subtypes="Iterative-KS"
                     /evalue="6.80E-48"
                     /label="ASD48_RS21265_PKS_KS.1"
                     /locus_tag="ASD48_RS21265"
                     /protein_end="390"
                     /protein_start="71"
                     /score="155.5"
                     /tool="antismash"
                     /translation="AIREALESSGLDLDTVDRDRVAVVVGSSLGAMPTLESVHADLVHE
                     GKLDAERAAAVQLPCVGDYIAAEFDLRGPRVVLSNACAASAVALGYAAELLWKGDVDHV
                     ICGGVDPLASLSAYGFSALGALDPEPCSPMSASTGLTLGEGAGFMVLESADRAASRGAR
                     VLAELGGYGLSCDGYHQTAPDPSGKGACAAMAQALDTAGLTPQDVDYLNLHGTGTPAND
                     ASEPKAVKLLFGSSVPPASSTKSILGHTLGAAGAVEAVVSTLAIDRGTLPPTVNTRGVA
                     QPFGLDVIPDTGRAGTRPEVVISNSFAFGGNNASVVLN"
     aSDomain        36047..36883
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS21265_PKS_KS.2"
                     /domain_subtypes="Modular-KS"
                     /evalue="1.60E-12"
                     /label="ASD48_RS21265_PKS_KS.2"
                     /locus_tag="ASD48_RS21265"
                     /protein_end="740"
                     /protein_start="461"
                     /score="39.0"
                     /tool="antismash"
                     /translation="GINPSRARRMDPLSLLAAAAVADLYGRHGKPSRAEAEGTGIVFAT
                     GYGPVTSVLQFHKGVLQQGISGANPALFANTVVNAAAGHVAMLHRYRGYTATIANGGTS
                     SVLALQLAARVIARGMADRIMVVIADEFPEQALATQAGLPGYARSGPVVPGGRSGMVLS
                     EGAAAVLLESERSASSRGADVLAKVRGYGASGEPAGIGRIGRDGEAWARALRGAMAEAR
                     VTPDEIDTVVSAASGYSLVDTAQSRALRLAGLLDRPTITPKALLGETYGSAGALGLV"
     gene            36982..37599
                     /locus_tag="ASD48_RS21270"
                     /old_locus_tag="ASD48_12810"
     CDS             36982..37599
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127983.1"
                     /locus_tag="ASD48_RS21270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12810"
                     /product="hypothetical protein"
                     /protein_id="WP_057603227.1"
                     /transl_table=11
                     /translation="MGALLGLVMDPVLRGAARPAPIDCLVTHHAHLPRDRMGRRLDASG
                     RSLIIEAVARVHGLDIGARDLTRDVHKRWHVPAHGLTASVAHCDGWSAVALSAGPVHIG
                     VDLQDERDRPAAMRWLGTLLGRRRPAEIRDFAECEALIKASHVTKETFAGVRLPAWRPG
                     WRPTNVGAYRVRSTTVAPAMHLALAADAPAPVRLHTSPQEPA"
     gene            37596..38753
                     /locus_tag="ASD48_RS21275"
                     /old_locus_tag="ASD48_12815"
     CDS             37596..38753
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127982.1"
                     /locus_tag="ASD48_RS21275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_12815"
                     /product="hypothetical protein"
                     /protein_id="WP_057603228.1"
                     /transl_table=11
                     /translation="MTATAAAVRPYTRRISQIERGYLNAAATGTPQLIQMIVEGEGRID
                     PDALRDAVRSATLASPGLAVRRRGAGWRADGPLPPVVELPGGDAFDAPFFHRDLDVVSG
                     PVCEVGLVAGPSTRLVVRASHIVTDGRGLRQWIADVFRVLRGEEPVGAASVVDDTHFRT
                     AAGKVPPAEPPARLDGLPAILGDGPADGTPLWIRRRVRAAPSAVTARVAAALSRRLGGE
                     TGRLIVPVDLRRHDRTVRSTANLTSRLVLDLHRDDSWKRLHGRIVRALLGKHEVAALDG
                     DFLRSNPFANSLREAQELDGTRFPCTAIVSDHGRIDTAELRTDGFHPTGFSTLPMLVPY
                     AEMFLSTCQVGDETELTLSCRSRPGAREAAEVVLDDIEHALTAPN"
ORIGIN
        1 aagagccaga ggtgagagcg ggggtggggg tacgaccccc gaaggggccc gtcgtcggcc
       61 gccgcgtctt agcagctcgg gttctgccac ggttccaggg gcgacggggc agctgtggcg
      121 ctccctccag cggcgataga agccgcaggt cagcggcgat ccaaccgttc tgcagggcat
      181 ccgccggcac tgcacaggaa tgagaagcgc tcaggccgcg gcttcgccgg ggtcctcgtc
      241 ctcgtcctcg tcttccgagg agccgccccg ctcgtaaccc gacacgtcga tctcgcggcc
      301 gtctgcgagc cgtctcttgt gcggggcgac gttgtgcttg gtgggcgggt tccgctgctc
      361 cttctcctct gcagagtcag cggccgaccc ggtgtcctgg gactcctcgg cgacgttctg
      421 ttcctcggca tgcctagcgg ccaggacggc gacggccaga gccgcgctgc cgaccgtgcc
      481 ggccacggcg aggatcttcg gcttgtgctt gctgacccag cccttcgcct tggcgaaagc
      541 ggtgggctcg ccgtcctcgg ggatgggttc gctgggcgtg gagtcagtca cgcgcacaga
      601 tctaccggac ccgtccctca cctgtcaggc aatcacccga catcgcccga tcaggttccg
      661 tggcgctcgt acgtcttcga gtcttcgcga aggtacatcc tctggccgtc gcagcggatt
      721 gccatcctcg ctctgtggcc cgcccgccgg gcggctctgc ttggcgtcgg ccgcgaggtg
      781 cctctcttcc catagagggc agctcggccg ctttctctac tacgcttccc gcgtggactc
      841 ggctgccgct tgcgtggaac tcgcatcgac ggctggaaac ggccgcgcga cgtgcgtcac
      901 gccgcaggca tcagggttgg cggcccgcgc gaccgccatg acataccggg aagaagagcc
      961 ttggccctca agaagacaga cctctacagc tcgctctgga agagctgcga cgagctgcgc
     1021 ggcgggatgg acgccggtca gtacaaggac tacatcctca cgctgctctt cgtgaagtac
     1081 gtctccgaca aggccaaggc cgaccccgac agtctcatcg acgtcccgcc cggcggctcc
     1141 ttcgacgaca tggtcgccgc caagggggac aaggagatcg gcgaccgctt caacaagatc
     1201 gtcagtcgtc tcgccgaggc gaacgacctg cgcaacgtca tcgacctcgc cgacttcaac
     1261 gatgaggaga agctcggcaa gggcaaggag atccaggacc ggctctccaa gctggtcacg
     1321 atcttcagtg acctggactt ccgcggctcg cgcgcggagg gtgacgacct tcttggtgac
     1381 gcctacgagt acctgatgcg ccacttcgcc acggagtccg gcaagagcaa ggggcagttc
     1441 tacacgcccg cggaggtttc gcgggttctg gccaaggtgg tcggcatcac caaggacact
     1501 cgccaggacc agacggtcta cgacccgacc tgtggctcag gctcgctgct tctgaaggtc
     1561 gcggccgagg ctccgcgagg catcacgatc tacggccagg agaaggacaa cgccacgtgg
     1621 gcgttgtcca agatgaacat gatcctgcac gggaacgaag acgcagagat cctcaagggc
     1681 gacacgatca cgagccctca gttcaccaac gggaacgcac tccagacgtt cgacttcgcc
     1741 gtggccaacc cgccgttctc gatcaagtcc tggagcaacg ggctggagca ggagtacggc
     1801 cgcttcgagt acggccggcc accggagaag aacggcgact acgccttcct gctgcacatc
     1861 ctcaagtcac tcaagagcac gggcaaggcg gcggtcatcc tcccgcacgg agtgctcttc
     1921 cgaggcaacg ccgaagccga catccgtcag cgcctgctga agcaagggtt catcaagggc
     1981 atcatcggtc tccccgcgaa cctgttctac gggaccggca tccctgcctg catcatcgtg
     2041 ctcgacaagg agaatgccgt cggccgcacc ggcgtgttca tgatcgacgc gtccaagggt
     2101 ttcatcaagg acggcaacaa gaaccgtctc cgcagccagg acatccacaa gatcgtcgac
     2161 gtcttcaccc ggcagaccac gattgaccgc tactcgcgca tggtcccgct atcagagatc
     2221 gccgacccga agaacgacta caacctcaac atcccccgat acatcgactc ctccgagccc
     2281 gaggacatcc aggacctcca cgcacacctg cacggcggca tcccgaaccg cgatctcgac
     2341 gcgctcagtg gctactggga tgccttcccg cagttgcgag accaactgtt ccggctgaac
     2401 cgtcctggct acagtgacct gaccatcgac gtcagtcagg ttcaacaggc gatccttgat
     2461 tcgcccgagt tccagaagtt cacccaagag gcccgggagc ttaccactga gtggttcgcc
     2521 gcccatcgca agaggctcga agggatcgac gagactactc ggccaaatga cctgattgcc
     2581 gttctcggcg acgacctgct ggcccgattc aaaccagttc ccttgctgga cgagtacgac
     2641 gtctacgaac agctcatgac gtactggcac gacgtcatgc acgatgacgt cttcatggtc
     2701 atgaacgacg gctggctcga agcggctaag ccgcgccaga tcgtggtgga caaggaccga
     2761 aagctgtccg agacccctga cctcgtggtg ggtacgggcc gcagtgccga gaagtacaag
     2821 atggatctcc tcccaccgaa tctgatcgtt gagcgctact tcgccaagga acgcgctgag
     2881 gtcgatgagc tcatttcgct atcggaggaa gcgagtcgcc tggtcgagga gtacgtcgag
     2941 gagcatgccg ttgagggcgg gctactggcg gaagcgatgg acgatgaaaa gatcaacaag
     3001 gcactcgctt cggcccgcct gaaaaaggcg cgacacgaag gtacggatgc agacgaggtg
     3061 gcctccctgt cacacctcat caacctgtac aacgcggagg cggtagcgaa gaaggcggcc
     3121 aaggaggcgg aagctgcgct gagtcttgtc acgctgaaga agtacggcga gctcgccgag
     3181 tctgagatca aacaacttac gcttaacgac aagtggcagg ctacggtcac ggaccgtgtt
     3241 gctcaggtgg ttgaatcgct gacgcttacg ctggtggggc ggattaagga actcggcaag
     3301 cgctacgcag aaacagttga cgctatcaaa gccgatttgg aaaatatcga ggctaaggtg
     3361 gcacgtcatc tttccgccat gggggttatg taatgacctc tgaaaattcg ccttggcccc
     3421 ggttggcgac tggggttatt gcccaaccgc gcttgggtgg caactatagg aacgccgggt
     3481 ctgtgtctag gcgaccgctc atcaagatgg gaaacattgc gcgggttaac atcgacttgt
     3541 cgcgcattga gtacatcccg gactcggaag cggttagccc attgcaccgt ttgcgatacg
     3601 gtgacgtgct ttttaatacc aggaatacac tcgaccttgt cgggaaagtc tctatttggc
     3661 gtgacgaact tccggttgcg tactacaact ccaacattct gaagctcgaa ttcaagtctg
     3721 agtactgcgg tgattcgcgg tactttgggt acgcgctgaa ttccgcagaa agcattgaag
     3781 cgatccgcaa cttggcgacc ggtacaacga gtgttgccgc cgtgtacacg cgcgacttgc
     3841 ttaaactgga aattccggtt ccgtcaaagt ctgagcagtg tgcaatcgct gatacgcttg
     3901 aagatgtcga gcggttgatc tcgtctttgg tgcttctgat cgccaagaag caggcgatca
     3961 agcaggggat catgcagcgg ctcctcaccc gaagggtgcg ccgctctgat ctctccgagc
     4021 cgcgggagga aactcgactg cgtgacctcg gtatggtgta cggagggctt acgggtaaga
     4081 ggaaaggcga cttcggtcaa ggcgtggctg ccttcgtgac gtttctcgat gtcgtaaata
     4141 acgttcgcct gatgacgcct gagcttggac gcgtccgcgt ccacgagtct gagccgcagc
     4201 atagagtgat gcgtggggac gttctgttca atgggtcttc cgagacgccc gaagaggtgg
     4261 ccctggccgc tgttgtcgat ttcgatgctg ggtcgaacac atatctcaac agcttttgtt
     4321 tcggctatcg gattcggcgg ccagatcttg ttgatccgac gttcttggcc tacttcttta
     4381 ggtctggtgt cggtcgggcg tcggtcgcgt ctctggctca gggtgcgact cgttataaca
     4441 tcgctaagag taaattcctc gacctcgccc tggctctgcc gtgtctggag gagcagcagg
     4501 ggaccgtcgc cgttctgaac gatagcgagg aagagatcga atttctcagg gcccggctcg
     4561 ctaaagctcg ggaaatcaag cgtggcatga tgcaggagct cctaaccgga cggacgcgcc
     4621 tgcctgttca gggggagagc agcgaatgag cgatgttggg caggtcgagc gcgaggccca
     4681 gaagcgggtc gtccggctgt tcaaggagca gctgagctac cgctaccttg gcaactggga
     4741 gtaccgcacc ggtaactcga acatcgagtt cgagttgttg gaggcgaacc tccgtgctcg
     4801 cggctacgac agcactctca tcagcaaagc gatcgaccac ctgaagaagg ccgccgcact
     4861 tggcggcggt cgtgacttgt acgaggcgaa tcgtgccgtc tatgagttgc tgcgctacgg
     4921 ggtcaaggtc aagccaggtg ctggcgagca gtacgagacg atctggctca ttgactggag
     4981 cgacgcgcag gccaatgact tcgtcgttgt cgaggaggtg acgattgttg ggaagcagac
     5041 gaagcgaccc gacatcgtgc tatatgtcaa cggcctggct ctggtgaccc tggaactgaa
     5101 gcgttcccgg gtggccgtga gcgagggtat ccggcagagc atcggcaacc agaagcctca
     5161 gttcatccgg tcgttcttct ctaccgtcca gctcgtgctc gctggcaacg acgtggaggg
     5221 cctgcgctac ggcgtcatcg atacgcctga gaagtactgg ttgcagtgga aggagccctc
     5281 cgacgttgag gagccgctgg accgggctct gcttcagatg tgcggtaagg agcggctgct
     5341 tgaactgatc catgacttca ccgtcttcga ctccggtgtc cgtaaggcgt gccgtcacaa
     5401 ccagtacttc ggcgtcaagg ctgcccagga acgcattggc cgtcgcgagg gcggcatcat
     5461 ctggcacacc caggggtcgg ggaagtcgct cacgatggtg tggctggcga agtggatccg
     5521 ggagcaccaa aacgacgccc gagtcctgct gatcaccgat cgcaccgagc tggacgagca
     5581 gatcgagaag gtcttcaacg gcgtcaacga gcagatctac cgcaccagta gtggtatgga
     5641 cctgctggac actctgaaca agtctaccga gtggctcatc tgctccctcg tgcacaagtt
     5701 cggtagctcg gcggatggta aggatggatc cgaggccagc aacgagttca tcaaagagct
     5761 caaagccagg atccccaagg gcttcaaagc caagggcaac ctcttcgtct tcgtcgacga
     5821 ggcccaccgc actcagtccg gcaagatgca cgacgcgatg aaggacctgc tgccgggcgc
     5881 catgttcatc gggttcacgg ggacaccgtt gctcaagacg gacaaggcca ccagcatgga
     5941 gaagtttggg tcgttcatcc acacctacaa gttcgacgag gccgtcgagg acggcgtcgt
     6001 gctcgacctc tgttacgaag cccgctccat cgaccagcac ctgacatcgc cggcgcaggt
     6061 ggacaagtgg ttcgaggcca agacccgcgg catgaccgac ctgtccaagg cagagctgaa
     6121 gaagcgctgg ggcacgatac agaaggtcgt ctcctccgag cctcgggcga agcagatcgt
     6181 gcaggacatc ctgctcgaca tggagagcaa gccccgcctg atggacgggc gtggtaacgc
     6241 catgctcgtg ggcgagagca tctaccaggc atgcaagttc tacgagctgt tctgcaacgc
     6301 gggcttccga gggaagtgcg ccatcgtcac cagctacgcc ccgagtcccg gagatatctc
     6361 caaggaggac tccggcgcag gccagacgga gaagctgcgt cagtacgaca tctatcgaaa
     6421 gatgctcgct gaccacttcg gcgagtccga agacgccgcc atgacgaagg tcgaccagtt
     6481 tgagcaagag gtcaagcggc agtttgtcga ggagcccagc cgcatgcgcc tgctcatcgt
     6541 cgtcgacaag cttctgaccg ggttcgatgc gccgagtgcc acgtaccttt acatcgacaa
     6601 gaagatgagc gatcacggcc tgttccaggc gatctgccgg gtcaaccgac tcgacggaga
     6661 cgacaaggag ttcggctgcg tcgtcgacta ccgcgacctg ttcaattccc ttcaggacgc
     6721 catcaccgac tacacgtctg gtgcactcga cgggtacgaa ccacaggaca tcgagggcct
     6781 gctgactgac cggatcgaga aggggcgaga ggctctcgac gaagcgctgg aacgaatccg
     6841 cgcgctctgc gaggtggttg cgcagccccg gaacacgctc cagtaccagc agtacttctg
     6901 tgcggccgat cccggcaatg ccgagcagct caaggccaac gagcccaagc gtgtcgagct
     6961 ctataaggcc gttgccgggg ttacgcgggc cttcgccaac ctggccaacg acatggaagc
     7021 cgccggatac accagccagg aggcccagga catccgcgct gagatccggc attacacgga
     7081 tgtccgcgac gaggtgaagc tcggagccgg cgaggacgtt gacttcaagc agtacgaggc
     7141 cggtatgcgg ttccttctgg acacctacat ccaggcggac gcgtccgaga ccgtgtccga
     7201 cttcgaggac accggcctcg ttcaactcat cgtcgaactg ggtgccgggg ccctcgacaa
     7261 gctgccaaag ggaatcaaga gcagccctga ggccgtcgcc gagacggtcg ccaacaacat
     7321 gcgcaagctg atcattgaag agcatgcgac gaacccgaag tacttcgaca agatgtcgga
     7381 gctgctcgac gccataatcg agaagcggcg ccagggcgcg atcgagtacc aggactacct
     7441 cgccaaactg ctggagactg ccgcgcagct cggcagagga gagtccgacg acacgtacaa
     7501 gtaccccgcc tgggccaata acggggcgaa gcgggccttg gtcgacttct tcctccctga
     7561 tgagcgactg gctgtcgagg tcgacaccgc ggtgctccac tccaagccgc atgcatgggt
     7621 gggtaacccg ttaagggagc ggaaggttcg gaacgcgctg aagcgagcgc tgcccgacga
     7681 tttcgaccgg cttgatgagc tccttgaact ggtgaaggca aggcatgagt accactagcg
     7741 cccgtctcgc agtccggggc attgacgtcc acgtggtcta caaggacatc aagaacctgc
     7801 acatcggcgt gtaccccccc atagggcgcg tccgggtggc cgcgcctcag cagctggatg
     7861 acgatcaggt ccgcctggcc gtcatccagc ggttgccgtg gatcaagcgt cagcaggatc
     7921 aactgcgctc ggctgagcgt cagtcagtgc gcgagatggt cagcggagag tcccactacg
     7981 tgtggggtgt gcgacgacgc ctgaaggtca tcgagcgacc gggacgcccg catgtagaaa
     8041 tcgacggcga ccgaatgctg ctctacgtgc cgagcgggac aggtgaggag cgccgtcgcg
     8101 acctgctcga ccggtggtgt cgtgagcaac tccgtcaggc gatccctgcg ctcatcgagc
     8161 gctgggagac gaagctcggg gtttcagtgc cgtggtgggg tatccgccgg atgaagacca
     8221 agtggggctc ctgcaaccgg gagacccgcc gcctgtggtt caactccgaa ctggccaaga
     8281 agcatccaga gtgccttgag tacgtcgtcg ttcacgagat ggtccactat ctcgaacggg
     8341 gacacggcca gcgcttcgcc cagctgatgg acggcttcct gccggactgg cgtagtcgcc
     8401 gtgatggcct gaacgctgca ccgctctctg atgagctgtg gatggggcgt tgagtacacc
     8461 aaggactttc cgtggccgga cagggccttc tccacggcaa cagtctcgta tctgccctga
     8521 agagcagggc ggtcgtgaac gcatttccgt tgctcgaaaa tgtcgagtga cgtttatcag
     8581 gtatccgagt taatgactgg ggaggcgtcc agcttccctc tcggttccat caaaagacga
     8641 tgacgcggaa ggtgctgacc ccatggcgaa gcttcggttg accgtagggc gggggcacgt
     8701 cgaggagctg gcacgcctgc gccatcctgt cggagccatc gaggagctga tctggaactc
     8761 actcgatgcg gacgccgaga acgtcaccgt tgtgcttgag cgcaacgact tcgacggagt
     8821 cgaccgagta gccgtgatcg acgacggcac tggtattgcg gcggagaagt gcagcgacta
     8881 cttcgagcag atcggtacgt cctggaagaa gcgcacgcag gtcagcgagg tcaagaagcg
     8941 cgtgctacac gggaagaacg gtcggggccg agtccgggcc ttcgcgctcg gcagcgaggt
     9001 gcgctggacc agcgtgagcg ggatgcaggg ggatctgccg tcgtgtggtc atcgagtccg
     9061 accgcggctc catggacgag tttgacgtca gcgatcccga gccgacgacc gacgcgacgg
     9121 ggacggcctt cgaggcgttc ggcggggagg acctccagaa gctgaccgag gacgccgccc
     9181 gtaccgcact caccgctgcc ttcgcgcttc acttggaggc gtacccggac atctgcatca
     9241 cctacgacgg gacgcggctt gacccggcgt cggagcaggt tcacgtcgat acgtacgagg
     9301 tggcggcccc gccgggcagc tctcacccgc cggctcagct gaagatcatc gaatggtcgc
     9361 gtccgtattc ccgggctctg atcctgtgtg acggccgagg catgtccttg gcgcagctga
     9421 agccggagat tcaggctccc ggcttccact tcaccgcgta cctgtcctgg tcggggttcg
     9481 aggacgattc ggtcggcgac ctcgcctttg ccgactggac accggagggg cctgctgccg
     9541 aggtgctggc cgaagcccgg gagcgtatgc gtgagcactt ccgctcccgt gccgacgaac
     9601 gtcgtcgtga gctcgtcgac cagtggcgtg cggaaggttt ctacccgtac atgggcgagc
     9661 ccgccaacga ccaggagcgt gcggagcgtg agaccttcga cgccgtggcg acggcggtcg
     9721 tccggcacct gccggcgagt aagagggcac agaaggtgtc cttcgcgctc ctgcgctccg
     9781 tcctgaccca cgagccgggt gaagtgctgc gcatcgccga ggagctcttc gcgctctcca
     9841 agcaggagca gacagaactc agtcgactgc tggaccgcac gccgctgtct gccctgatca
     9901 aggcgtcgac agcgacgacc ggacgtctcg acttcctgtc ggctctggag cacctcgtct
     9961 tcgagcccgt ggccaagggg cgggtcaagg aacgtaccga gctgcaccgg atcctggaga
    10021 acgagtgctg gatcttcggc gaggagtacg gactgcacgc cagtgaccgc agcctgaacg
    10081 aggtgctgag gcagcactgc cgtctgctcg gccgggacgc gccagctccg gaccccgttc
    10141 tgagagagga cgggaggaag agcatcgtcg acctgatgct gtcccgtgcc gctcggcaga
    10201 ggaaagggga gcgccaccat ctcgtggtgg aactcaagag gtcgagcgtc acccttggta
    10261 tggccgagtt ctcgcagatc aacagctacg cgcaagcggt catgaacgac gacaggttcc
    10321 gggaccccaa ggtgacctgg gacttctggc ttgtcggcaa tgctatggaa gacggcctac
    10381 gccaactcgc ccaccagcct gaccgaatgc ccggatgtgc cgtcaatcag cccacgtacc
    10441 ggatctgggt gcgcacctgg ggcgagatca tcgaggacgc tcaggaacgg ctccgcttct
    10501 acagcgagca gcttgagtac cagtcgacga ccgagcacgc catggactat ctgatcaggg
    10561 agcacgccga tgcggtcgtg gacctggtca gcgacggcac ggtgccggtg gcgaggactg
    10621 gggacagcgg atcgattgga gctgccacca ccccgtgagg cccggactgg gccgacggtc
    10681 gtacgcggcg acggggaagg tcaacggcgt cagggcagga tgtgagtctg gacagctcct
    10741 gacgagaggg tcgccccgcg gccccgagga aggcagcggc gaagaggttg gtacgtaagg
    10801 ggaagtcagg ccgggcaagc cgtcttcctg aagagcggcc ttggccgcat cctggctgac
    10861 ctccttcgcc gctgcacagg cttccggctt cgccgctgtt cgtcagcgcg taagccgtct
    10921 tgcccctgta gatggccccc ttttgagggg accatcactt tcaggatccc ggctttccag
    10981 ttctccagtg gactgtgttc tggtcggccg caggccgcca gcgtccatag agctggcgta
    11041 cttacgtaag taggggggag gagcgaggct tgccgagcgg agcgaggtag ctggtggtgg
    11101 tgagcatttc tataagggag cggcatcacc accaccacgg cttacgccgc ttcggtagtt
    11161 cggcggaccc acctgccgcc gacgtgagtg agggcggcgc tgagcttggg gcgcagggtc
    11221 tccggcttcc tgtctgcatc ctgtgcgtac ttgttcgcaa gggccttgat ggttgtctct
    11281 tgcggctgct cttcgaggac gcgggcgatg agggcttcat cccatgggcc cgccttgggc
    11341 cggctgatgg ccctcaggcc gggctcgata cgttcccaga tggggatctc gttctccggg
    11401 gaggcgcggc gcacagcgac ggggatgtcg agttcttcga tagctcggtt gttggccgtc
    11461 tggagcctcc gtccctgctt gccggagttg cgcagggcga tgaggccacg ggcggcggcg
    11521 cccatggcgc ggcctccgat cggggaggac gcaacgctca ttccttctcc agtccccttg
    11581 ggggtgtggg tgaccagaag cgttgggatg ccgagatcgc tgatcggtcg gaggctgttg
    11641 acgaggcgct gcgcggtgac ggatgacgcg atgtcttcgc cgggggcgag tgccccgatg
    11701 acgttgtcca ggacgaagag cccgggcttg attcgggcga ggtcctcgta gatgcctgcc
    11761 cagtaccacg ggtctccggt gtcggagaaa gggaagacgg tcacggagtc gtagggaacg
    11821 gcgccgtcca tgcgctcctt cagttcggcc ggcgcaccgt cgtcggtgag gcccaagacg
    11881 atgtggtcga gcttcttgtg tacggggagc ccgaggaacg tcggatcgcc gttgagtagg
    11941 gcggtgctca tgcctacggc gagcagggtc ttaccggctt tgggttctcc ggacaggatg
    12001 gtgatccggg tggtgaggag atcaccgatg aggaacgctt cctcgtacgg gacgcgctcg
    12061 atctggtgga gctggagtcc cttgtccttg atggctccca tgatgggtgg ccgtccttcc
    12121 gtgtgcggcg ctcaggtgcg ccgacgtcct cccgccgagc gacgggatca tgtgacctcc
    12181 tttcggtcag tggggaatgg ggaggccccg tcaggccgag accgggcact cccgatcgat
    12241 ccagcggtct acctctgaca gtcggaagcg caggctgccg ccgaccttcc gggacgggat
    12301 gccgagcgtc cggtggttgt tgtagatcca cgcgggcttc ttgcccaggt actcggccag
    12361 ctcgtcaacg gtcatgaggc ggtggtggcg caaaggcggg ctcctgtcga tgcatgggcg
    12421 gacctgaaca tcttgagcgc gcaagatcgg cgtggtcaag tccggatctg tcacatccgg
    12481 acttgacgat gctgtggcgc ctgcctacgg ttcggatatg aactcgacac ctcagccacc
    12541 agcacccgaa ccgtggaatg gtgtgaccgt catcaagcgc acgggtgcat gggtggtgac
    12601 tatgtactgg cccgagggcg ccagcggatc ggtagggccg cgtgaggtcc atgtggttcc
    12661 tgcggacgac gctgatccgc aggaggtcgc gcggggtatc tccagcaccg ttctccggcg
    12721 gatcaatacg acgccgagtc gggacttcgc cgcgatgcgg tcccttgaga aggctgctga
    12781 catggatatc cgccagcttg gcaagcggct gacttctctc ccgagcggtc tcacggacga
    12841 gcgcctggcg gtgctgtctg ccctctacgt gcacttcgtg gatgcggggg agcgtgcccc
    12901 ggctcaacgc ctggcggtgg gcttcgactt gaacccagcc accgtgaagg ggcacctgcg
    12961 cgccgcccgg cagagggggt tcctgacgaa ggtcgaaggg aaagcgggcg gacagctcac
    13021 ggacaaggcc gtacagacac tcagggggat gaagagtggc gcaggtactg aagaagtgtg
    13081 actgccggaa caagacccgg tgcgggcacc ggtggacggt ccgctaccgg gagccgggag
    13141 ggaggagcgc gcggcagcgg gagaggtcgt tccccacgaa gaaggaagcc gagagcttcg
    13201 gcgtcaaggc ggagaacgac aagcggcagg gtgtttacat cgacccccag ctcggccaga
    13261 tctcgctgcg caagtgggcc gaggagtggc tggagcagca ccaggtgaac gagtccacgc
    13321 ggcgcaacta ccagggcttc ctctccaacc acctgatacc ggagctgggc tcccgcaccc
    13381 tcgccggcct gaccgtcgcg gacgtgaaga agctccaggc ttcgatggtc ggccgtgggt
    13441 tgacggccgc gacggtcaac gaccgcctga acatcctgcg cagcatgatg acggcggccg
    13501 tgaaggagcg ccggataccc gacagtccgt gcgacgaggt gccgccgctc aaggcggcgg
    13561 gcgctgcggt cgatcccgac gagatcccga cactggccga ggtgtacgcc atcgcagcgg
    13621 ccatgtccga gcagtaccgg ctcaccgtat ggctccaggc gggtgcgggg ctgcgcatca
    13681 gcgagaccct cggcttctcg gtcgactgcc agcgcgacgg cttcctccgg ctgcgccgcc
    13741 agattagcgc caaggcgaat cagggcgact gcgtcacccg cttcgtgccg ctgaagcacc
    13801 gcacggcgga ggagttccga gacgtaccca cgccgacctt cctcgaccag gagatcggac
    13861 tgcacctaaa gcgctgggga acggtcgtac tcgatggcct ggaggttctg ttcgccccgc
    13921 gtgagcgcgg aaagggcaag atgcccacgg cgtcgacgta cggctaccac tggcgcaagg
    13981 cactgaaggt cgccggagtg acgacgccag acgggaagcc gaagtacacg ccgcactcgc
    14041 tgcggcactt cttcgcctcg acggcgttgg cgaacggcgt cccgatccac gaggtgagcc
    14101 gctggctcgg gcaccgcaac atcaagacga ccgtcgacac gtacgggcac ctcgtcccgg
    14161 aggcgtggga ccgctgccgc gacgtcatgc aggaggcgct gcgcccgtcg gttccccgcc
    14221 aggcggcgga gccatcgacg gcgctggcgg cgtgacgtgc tgactgctcg acaccgtgct
    14281 gacttggtgc tgaccctagg cctcttccag gggtggaatc ccttgggaat actgggcaga
    14341 agggggttcc atgaacgttc cgcttcaacg tctgagcgga tgccatggca tcacgttact
    14401 gatctatcaa acatgcaggt cagaaggggt ccacctcatt gcgggtgggc ctctggcgtt
    14461 ttcctgtgcc ggatggttgc cggatttccc tgcccttcgt catctgctct cacctcttct
    14521 ccccgtcccg tgccggatga gccgagtcgg cgacacgagc atctgggctg cctcgatggg
    14581 ggcatccccg gttgcaccac ctgacgggac atgcccccgc cgtctccgcg cgcacaggat
    14641 gcgggcccgc aaggcgcgtg ttcccatggg gccgtcggac ctgagaggga ccgtggcgcg
    14701 ggagtctccc gcgcggccgg ggggccgtcc cgctcggtgg agcgccgcca ccggcgccgt
    14761 ccgcccgtga gtcccgcatc cttcccgcgc ccgccgcgtg tgttcatgga gcgcatcgag
    14821 cccccgccgt aaggaatccg gatgaccgag tcgcctcagg agccgggtcc gactcaccgg
    14881 gaacatccgc ggcccggccc gggcggacgg gcgtctccac ctgccgacag gtacggcgag
    14941 gagggtcccc cggagcgccg gcggaaccgg ctgggcgcgg tctgggccgc cgcgccggcc
    15001 atgcccccgc gtaccctgct cgacatactg gaggcgtccg tacgggtgta ccccgacgca
    15061 cccgcgctcg acgccgacgg cgtggtcctc agctatcgcg agctgtggga ccgggccggc
    15121 ctgctggcac gtgacctcgc tgtgctcggt gtcggcgtgg gggaccgggt cggagtccgg
    15181 gtgccgtccg gaaccgtgga cctctacacc gccgtgctca cggtgctccg cgcgggcgcg
    15241 gcctatgtcc ctgtggacgc cgaggacccg gaccggcgtg ccgcggtcgt ctgggccgac
    15301 gcggaggtct gcgccgtcat cggcgaaagc gggaccgtcc gtccggtccc cggccgcgtg
    15361 ccgtgcggcc gggcgggtca gccgcggccg gccgacgacg cctggatcat tttcacctcc
    15421 ggcacctcag gaccccccaa gggcgtggcc gtgacccacc gctcggccgc cgccttcgtg
    15481 gacgcggagg cacagctgtt cctccggcac cgaccgccgg gaccggggga ccgggtgctg
    15541 gccgggctgt ccgtcgcctt cgacgcctcc tgcgaggaga tgtggctcgc atggcgccac
    15601 ggcgcctgtc tggttccggc gccccgctcg ctggtcagag ccggtgccga gctggggccg
    15661 tggctactgg agcgcggtgt caccgtggtc tccactgttc cgaccctggc cgccctgtgg
    15721 ccggccgagt gcctcacggg agtgcggctg ctcgtcctgg gcggagaggc gtgcccggcc
    15781 gaactggtcg accggctggc cgctccgcag cgcgagctgt ggaacaccta cggtcccacg
    15841 gagaccaccg tggtggcctg tgccgcccgg ctggtccccg gtcggcccgt gcgcgtcggc
    15901 gcaccgttgg cgggctgcga agtggccgtc gtgggcccgg acaacgagcc cgtggcctgg
    15961 ggcgagatcg gagagctggt gatcggcggc gtcgggacgg cccgttacct ggaccctgcc
    16021 aaggacgccg agaagttcca gccgcaccct gttctgcgca gtgtgcgcgc ctatcgcagc
    16081 ggcgacctgg tgcgcgccga ccctctggga ctggtgtacg tggggagggc ggacgagcag
    16141 gtgaagctgt ccggccgccg tgtggaactc ggcgagatcg atgccgcgct ccggtcgctg
    16201 cccggggtaa gcgccgccgc tgccgccgta cgcgccaccc gggcgggcgg ccaggtcctg
    16261 gtcgggtacc tggtcctgca cggggacggc cgcccgtgct tcgacaccgc tgccgccagg
    16321 gtcctgctgc tcacccggct gccccggccg ctggtgcccc tgctggccgt cgtcgacggt
    16381 cttcccaccc gcgcgtccgg caaggtcgac cgtgacgccc tgccctggcc gctgctcgat
    16441 cagcacgcca caccgggagc cggtaccgca ccgggggcgg ccccagggcc gaccggcacc
    16501 gcgggatggc tgaccgacct ctgggagagc ctgctcggac tccgccccga ggaggacagc
    16561 gatttcttcg ccctcggcgg taccagcctg tccgccgcgc agctggtgtc gactttgcgc
    16621 gaacgcgtcc ccggggtttc cgtcaccgat gtctaccggt gtccccggct gacggacctc
    16681 gccgcacggc tggatgacct ggaggtcggc ggcgagcccg cgcgcacgat ccgacccacc
    16741 ccccgctgga ccggtgcggt acagctcgtg gtggtgaccg tcctgtgcgc cgtggtcggg
    16801 atacgactgc tggtcctgct cgccgcgctg gacaacctcc tcggtccgcg gtcatgggcc
    16861 ccacggagtt cgtggtggct gatcgctgcg ggctggctgg ctctgtccag cgcccccggc
    16921 cgcgtcgtga tcggggcggc cgtcggccgg ttgctcaccg ccgggttccg acccggtacg
    16981 cacccccgtg gcggctcggt gcacctgcgg ttgtgggcgg ctgaacgcat ggggaccgta
    17041 ctcggtacgg ccacactgct cggcactcac tgggctgccc gctacgccaa ggcgttgggc
    17101 tgcgcggtgg ggcagagcgt ggacctgcac gccatgccgc cggtgaccgg gatggcccgt
    17161 ttcggctccg gatgtgttct ggagccgggg gcggacgtgg ccggctggtg gctggacggc
    17221 gatgtgctcc atctgggccg ggtcgagatc ggggacggcg cccgagtggg cgcccgcagc
    17281 atgctgatgc ccggcgccaa ggtgggaagc ggtgcggatg tcgcacccgg cagctgtgtg
    17341 gagggcgaag tgcccgcgga cgagcggtgg cacggctcac cggcacggcg gatgtccggt
    17401 gccccgcgcg cgggccacga ctggccgcag ccggtccggc gacgctcgcg gcgctgggaa
    17461 ctggcctaca gcgcggcctt gtcggccctg gggctgctgc cgctggtggc ctccctgccc
    17521 gcgctgctgg tcctgaaccg tctggtgggc gacgaacatg gcctcggcgc cgtggtgctc
    17581 gacctgctgc tgctgacccc gctgctcgtc ctgctggcga tgggctgtta cgcggcgctg
    17641 accgtggtgc tggtgcggct cgcgggccgg gttctgactc ccgggcacca tccgacgtgt
    17701 ggcagggtca cctggtgcgc ctggtgggtc gcacggctca tgagtatggc ccggacctcg
    17761 ctcttccctt tctacgcggg cctgctgacg ccgttgtggc tgcgactgct cggggccagg
    17821 gtcgggcggc aggcggaagt ttccaccgtg ctggggctgc cggcactgat gcgggtcggt
    17881 gaccaggcat tcctcgccga tgacaccctg gtggcgccgt tcgagctgcg tggcggctgg
    17941 ctccggctgg acttctcccg cgtcgggcgg cgtgctttcg tcggcaactc cgggatcgtg
    18001 ggaccgggcc gggagcttcc cccgggcgcc ctggtcgggg tgctctcgga tgcccccgcg
    18061 cacgccgaac ccggatcgtc ctggctgggc agaccaggtc tctcattgcc ccgggtgcgg
    18121 gagaaggggg atcctggacg gacctgggcg ccgccgcgga gactggtgct cgcccgggca
    18181 gccgtggagg cgtgccgact ggtaccgatc atgggtacgg ccttcatcgg cagcctggcc
    18241 gcggtggcac tccaagtgct cgccgctcgc cacgggctgc tggtggccgc cgccctttcg
    18301 ggagtggtgc tgctgggcgc gggcgtactc gcctgtctgg ccaccactgc ggcgaaatgg
    18361 cttgtggtgg ggcggttcag gacaggccgc cacccgctgt ggagttcctt cgtctggcgg
    18421 aacgagctct acgacacctt tgtcgaggaa ctggccatac cctggctcgg ccggctgctg
    18481 accggtacgc cgttcctcaa tctgtggctg cgctcgctcg gagcccggat cggccgcggc
    18541 gtgtggtgcg agacccactg gctgcccgag accgacctgg tccgtatcgg ggacggagcc
    18601 tcggtcaacc gcggttgcgt ggtgcagacg cacgtcttcc acgaccgggt gttgcagctg
    18661 gaccagatcc gactggacgc gggagccacg ctggggccgc actccatcgc gttgcccggt
    18721 gcctcgctgg cggccggcac ggtggtgggg cccgcgtccc tggtgatgcg cggggagcga
    18781 gtaccggcca ggacccgctg gttggggaac ccgatcgctc cgagcacgcc ggcgagttcc
    18841 tgaccgggat ccgtgggatg tgcgcgacgt tccacgacgg ggccgggggc cggggggcga
    18901 ggggcgagtg ggagggccgg ggggctgtgg cctgctcggc ggaccgtggt gccgaggcgt
    18961 cggggtccgt cgggcgcgag gaacggccgt cgggggccgg ggtcgcggtg ggaggatgcg
    19021 gggaggcggg agaggggcgg gaagcgtggg gcgtggcgag cgggacatgg tcgcgagagg
    19081 agcgcgactg tccgaggcgg cgcgggcggt ggtcggcgac cacgcgaggg cggtggaggc
    19141 ggtccgggcg gcgctgaagc cgctccacga cgcggcggtg cagcgggagc ttgaggccat
    19201 cccgggaatc gctcacggca ggtgagtgaa cgccccctcc ccgtggcggt cgccggccgg
    19261 tcaccgccac ggggaggggt gagttcgtcg aggtccgggt cggacgcgca ggggccgcga
    19321 ggccggcgac gggggagggc tcttttcggc cgtcccgggg cccgataggg cagggatagc
    19381 cgcttcggtt cgggcggata gcggtgggcg caagagtgtt tctcgtcaag ccacccccca
    19441 ccggatcgtg aggacctgaa gatgaccgaa acccaactcc gcccggcgtc gggggaggtg
    19501 acgtcaccgg atgccgccgt gctcagcgcg gtcgtgaagc ggttcgccaa cgccaagggc
    19561 gaggagttca ccgctgtgga cgggctggac ctgcggatcc ggcgcggcga ggtcgtggcg
    19621 tttctcggac cgaacggcgc gggcaagacg accacgatcg acatgctcct gggcctcacc
    19681 cggcccgacg cgggacaggt ggagctgttc ggcgaggcgg cgcagcaggc ggtgcgcgcc
    19741 ggtcgcgtgg ccgccgtcct gcagagcggc ggactgctgc ccgacctgac cgtcgaggcc
    19801 accgtgcgga tgctcggctc gctgcacccc ggcgccgacc cggagaccgt gatgagcagg
    19861 gcaggcgtca ccaggctgcg ggaccgccgg gtctccgagt gctccggggg tgagcagcag
    19921 cggctgaggt tcgcgatcgc gctgctgtcg aacccggagt tcctggtgct ggacgagccg
    19981 accgccggga tggacgtggc ggcccgccgc gagttctggg ccaccgtccg cgaggacgcc
    20041 cggcacggca tgacggtcct gttcgccacg cactacatgg aggaggccga ccggttcgcc
    20101 gaccgggtgg tgatggtcga ccgggggcgg gtcgtcgccg acgggtccgc ctcctcgatc
    20161 cgtacccgta tcagcggtcg caccgtctcc gcgctgatca gcccgcagga cgccgccgcg
    20221 gtcgccgact ccgcgtccgt ccgctcggtc gcggtccgcg gcgatcgcca ctacttcgac
    20281 tccaccgatt ccgacgccct gctgcggctg ctcgtcacgc ggacctccgc caccgagatc
    20341 gaagtggccc cccgaagcct cgaagaggcc ttcatggcca tcacgcagca cggccgtacc
    20401 ggccaggagg tcccgcgatg accaccttga ccgcgccgcc cgcccgcccg cgtgcctcgt
    20461 ccttcagcgg agtcaacccc accttcgtcc gctacgagct ggcccgccgc ttcaaccgtc
    20521 agaccacgat cttcacgctc ctcctcccgg ccgtcctcta cctcgccctg ttccgtaccg
    20581 cgccggccca cggcacgctg ccgcacggca acttcgccgc ctggatgatg atcggcctcg
    20641 ccgtgtacgg ggcggcgatg gccgccacca gttccgcggc caccatctcc gtcgagaagt
    20701 cggccggctg gatgcgcacg atcgcgctga gcccgctcgc cccgcccggg tacctgctcg
    20761 tcaaggtctt gtgctcggtg gtgatggccg ccgtgccggt ggccatcgtc ggagtgctgg
    20821 gcttcgtcac cggcgcgcac gccgacgccg aggtgtgggt gacgtccctg gtcgtcgcct
    20881 ggctcggggc cgcggtcttc gcggcgctcg gcatctcgct gggcctggcc ctcaagcccg
    20941 acgtcgtgat gcacatgccg gggctgacga tgaccgcgct ggccttcctc ggcaacctgt
    21001 tcatcccgct gagcggcacc atgctcgaga tctcgcggta cacgccgatg tacggcgttt
    21061 ccaccctcgc ccgctacgcc ctcaccgacg gctacagctt cagcggcgag cactccagcc
    21121 tggcaggcgc cgtcttcaac atcgtcgcct ggttcgccgg gttcggcttc atggccgtcc
    21181 gccggttcgc gaagagcacc ggccgccagt agcccacccc acccggggcc gtcccacccg
    21241 gctccggccc accaggcctc accttgcccg acctctcttc acctcacctc gccccacccc
    21301 tcttcacctc gcctcgctca tctcaccgaa tccatccgca tcccaccgcc cgccggcccg
    21361 agcgccgtgc gacgggctca acacgaaagg gggatagaac acatgttcgc aatcatggcg
    21421 ccgggtcagg gctcccagac ccctggcatg atggccggct ggctgcgcga cccggtccac
    21481 gccgagcgcg tacgggcctg gtccgaggcc gcggactgcg atctcgtcca cttgggcacc
    21541 cgggcctcgg ccgcggagat cgcccgcacg gagaacaccc agccgctgct ggttgcccag
    21601 ggcctgctgg cccacgaggc gctggcggcg gcgggcgccg cggtcgcggc cgggcactcg
    21661 gtcggcgagc tcaccgcagc cgcctacgcc ggagtcctca cacccgtgga cgcggtacgg
    21721 ctggccgcgg tccgcggccg ggccatggcc gcggcctgcg cagaggcacc cacctcgatg
    21781 gcggccgtgg tcggcggcga cgaggcccgg gtgctggagc ggatcgccga actcggcctg
    21841 tacgcggcca cgttcaacgg tcccggccag atcgtggccg ccgggctcac cgagcgcctc
    21901 cagcagctgg cggccgcgcc cccgcacggg tcgaccgtca aacccctgcc ggtcgcgggc
    21961 gccttccaca ccccttacat ggagtccgcg cggcaggcct tcgccgccgc ggccgccacg
    22021 accgacttca cggccccccg cggggccctg ctctccaacg ccgacggcga ggtggtcgcc
    22081 gaccccgaga cggtccgccg gcggctcgtc gaccaggtgg tccggccggt gcgctgggac
    22141 ctgtgcctgc acaccctcgc ccgcctggca cccgggctga cggtgtcgct gccgcccgcc
    22201 cgcaccctcg ccaacatcct caagcgccgc caccccgaac tcgacgtcct cccggtcagc
    22261 acggcccgcg acatcggcaa ggccctcgtg cgcatcggcg agagcgcccg taaggaggaa
    22321 cccgcccatg ccggtgtctg acctcttcga gcgcgcccgc gccgagcgcc ccgaccaccc
    22381 cgcggtcgtc gacggcgacg gcaccctcac ctacgccgag ctcggcgcgg acgtcgaccg
    22441 cgcggcaggc tggctgcggg cccagggcgt cgcccccggg cagcgggtcg tccacgccgg
    22501 tggcaacgac cgcaccttcc tcgccctctt ccacgccacc ctccgtatcg gcgccgtctt
    22561 cgtccccgtc caccccgacc tgaccgacct ccagatcggc ggcatcgtcg aggactgctc
    22621 ggccgccctg gcgatctgcc cgcccggcgc gggggagcgg gccggccgga ccgtcccggt
    22681 cgggcaggcc cggcaggaga tccgggacgc ccccgccgac ggtttcgccg cccggatccc
    22741 ggacgacggc gtcgcgatgc tgatctacac ctcgggcacc accggccgcc cgaagggcgt
    22801 cgtctgcccc caccggcaga tgatcgcggc cgtcgaggcc gtgggcgcct gcctcggcta
    22861 caccgcggac gacgtggtgc tgtgccggct gccgctctcc ttcgactacg gcctctacca
    22921 ggcactgctc tgcgcccgca ccggcggcac cctcgtcctc gccgaacgcg gcggcgaccg
    22981 gggcctgttg cagaccatcg agcagcacgg cgtgaccgtc gtcccgctcg taccctcgct
    23041 ggcccagatg ctggcgctgc tccagagcag gctgcggcgg cccaccgggg tgcggctgtt
    23101 caccaacacg ggtgcccgac cgggccgggc cgtcatggcc gaactcctcg acgtcttccc
    23161 cgggtcggcg ttcgcgtcga tgtacggcat gaccgagtgc aagcgcatct cgatcctcga
    23221 ccccgccgag tacgccgccc accccgactc ggtcgggcgg cccatccccg gcgaccgggt
    23281 ccggatcgtc gacggccgga agcgggagct cggcccccgc gaggtcggcg agatcgtcgt
    23341 ggccggcacc accgtgatgg ccggctactg gggcgtcccg ctggaggcac agcaccgcta
    23401 cgtccgcgac gccgacggcg cgctggaact ccacaccggc gaccagggct acctcgacga
    23461 ggacggccgg ctctacttcg tcggccgcga cgacgacatg atcaagcgac gcgggatccg
    23521 cctcgggctg accgagatcg aggacgccgc cgagcggatc cccggcgtga tcgcggcggt
    23581 ggcgctccgg ccggagaccg aggacgcccc cctgctcctg gccgtgcaga cctccctcac
    23641 gcccgaggag atccgcgacc ggctgcggca gcgcctcgac cgggcccggc tgcccgacct
    23701 gatcgtcccc ctcgacgccg taccgctgac cgcgaacggc aaaccggacc gcaaggccgc
    23761 cgggctgctg gtccgcgccg ccgcccaccg ccccgccgga cagaccaccc gacagcccgc
    23821 acagacgagg accagccatg aaccagtcgc agtttgacca gctcgtcgag gagatctgcg
    23881 ccgtcacggt caccgacccg cagaccccgc tcgtggacct cggcgtggac tcgctccaga
    23941 ccatcgccct ggtgatggcc gtcgaggagc agtacggcat cgagatcgac cccgaggtgc
    24001 tcgccgaccc cgcgctcacc tcctcggccg gcctgctggc ctccgtgcag gaccagttgg
    24061 ccgccgcact gccggccaga gccgggagct gaccgccatg tggaccgaca cacgacccgc
    24121 ggtggagatg ccgcggctgt tcgaacgggg cggggacctg atatccttcg ccgggggcct
    24181 gcccgacctg gacgtcctgc cgctggacgt cctctccgcc cagctctccc ggctcctgcg
    24241 gctcggcggg aagctcgccc tccagtacac gaccccgcat gtcgcggggg ccctggtgcc
    24301 ggcgatcacc gacctgatgg cccgcgaggg cggacgtacg accgccgaga acctggtccc
    24361 gaccggcggc tcccagatgg ggctgatggc ggtggccctg ggcctcgccg ccccgggcga
    24421 gacggtcctg tgccagacgc ccgcctaccc cggcgccgcg gccgccttcc gcacggccgg
    24481 actgcacccg cacgcggtgc ccgaggacgc cgaggggctc gaccccgagg gactgcgcga
    24541 gacggtgcgg cgactgcgcg ccgacggccg caccgcccgc ctcctgtact gcaacccgac
    24601 cttccagaac ccgaccggcg ccaccctctc cgtcgcccgc cgcagggaac tgctcaccgt
    24661 ggcccgggag ctggacctgc tgatcgtcga ggacaacccc tacggcctgc tcggcttcga
    24721 cgggcggacc accgacaccc tccagggcct cgaccccgac cgggtgatct atctcggcac
    24781 cttctccaag gtgttcgcgc ccgggctgcg ctgcggctgg atcgcggcgc cggcggaact
    24841 cgcgagcacc ctgcgccgta cgaccgagat catggcgctg tccccgtcgg cgctcgccca
    24901 ggcggcgctc gccgccttcc acacccgctc cggctggacg gacctgatcg acgcctaccg
    24961 ggcgagctac cgggagcggt cgacgctgat ggccgacgcg ctggacgccg aactcggcgc
    25021 cgacgggccc tggtcgtggc agcggccgga cggcggcttc tacatctggc tgcggcaccg
    25081 caacggcgtc gacacgaaca ccttcgccga cgcggcggcc gagcacgggg tctccttcgt
    25141 gcccggctcg cacttcggca tcggcgggga gaacgccgac gcgctccggc tgtgcttcag
    25201 ccacgtcccg aagaagcgga tccccgaggg gatctcccgg ctggcggccg cgctcggtcg
    25261 acgggcggcg gaaggggcgg cggcatgacc ggcacgctcg aagcgacccg cgcgctcgac
    25321 tggacggcct tcggaccgtc gtaccggctg ggtgacagcg cctggcgggt atggggcgtc
    25381 ggactgctcc gcagcgcggg cttccccgtc tccggcctcg gcctgatcgg cggcccgcac
    25441 gccgcccgcg ccgccgcgca actgctggag accggcggcg ggacggacgg ccgggaggcc
    25501 ttcagcgccg cctaccgcgc cgacaccgac gccgaggccg ggcggctggc cctgctcgcc
    25561 accgacgaca aggtgcgcac cgccatcgcc tggcagaacc gcaccgtcta ccagatcctc
    25621 gactcgctcg ccgcgcgcaa gggcaaggag tccaagcgcc ggcagcgtga acgcaccctg
    25681 gccatgtact ggctgcggta ctgcgccaag gccgacacca tcggcttctt cggcccgggg
    25741 gcgtggatct ccgtcggccg ggggcagcga gccgtcgatc tcgatctcgg cccgtcgctc
    25801 acctcgcgga gccgtacctt cctcgaacgc tggacggtgg ccgcgctggc cgactggatg
    25861 gccgggcagc cgggcgcccg ctggtggttc ccgccgatgc tgcggcccga cgtgcacctc
    25921 gacggcgacc ggctcgtcat gcagggcggc cgtaccgtga ggctgcgcga ggacgacgtc
    25981 cgggtgctgc gcctggtgga cggcgaccgc ggcggcgagg ccatcgccga ggcgaccggc
    26041 tgggagccgg cgacggcgcg ggagcgggtg gagaaggtcc tgacccggct gctgcggcag
    26101 cgggtgctga cctgggacgc caacatcccc gtcgacgtcc gtgccgagga ggtgctgcgc
    26161 cgccgggtgg ccggcatcgg cgacccggag ctgttcgtcc gcttcgacgc ggtcctcagc
    26221 ggactcgacc ggctgcgcga cggcatcgac cgggcgtcga gcgccgagga gctcgtggcg
    26281 gcgctcgacc ggctcgacga gttcttcgtc cggacgacgg gacagtcggc ctcccgcgac
    26341 gagggcaagg cgtacgccgg ccgcacgctc tgctaccagg actccctccg ggactgccgg
    26401 atggacctgg ggcgggactt cctggacggc atcgcccgtc cgctggccct ggtcgcggac
    26461 gcggcggact ggttcggcaa ccggctcgcc gaactggtgg aggcggaggt cgccgggttc
    26521 gtgcgcaagg ccgcggcccg ccgccgcggg gacgtcaccc tcgccgacgt gtggacgcag
    26581 gtactcgggc tgttctgggg cgaccacgcc accccggtgg agaccgcgac ccgtgaactc
    26641 gccgagaagt ggcgcgaggt gctgcacctc gccgaggaac agcgggcccc ggtacgcctg
    26701 tcggtgtccg acatcgagaa gcgggcccgc gaggtcttcg cgaccggccc ggtgcgctca
    26761 ccccatctcg ccgtgcacag ccccgacctg caggtggtgg cccggtccgt cgacgccttc
    26821 aacgccggtg actacaccac cgtcctcggc gaactgcacg cctgcctggc caccctggac
    26881 ctgccgttcc tcgactggac caccgacgcc ggctcgctgc gggacaaggt gaacgcggcg
    26941 atcggtgccc ggcggctggt gccgctgctg ccggtcgagt ggaagcgcaa cagcggccgc
    27001 atggtgcccg ccccgatcgg cgccggcgac cggctgatcg gcttcacccg ggctccttac
    27061 gacgaccgca cgcgcgtcga ccccgccgtg tccgtcgggc tggccgagaa ggacggcacc
    27121 gtcaccgcga ccacccccga cgggggagtc tggagcatcg ccgagctgct cgccgtgccc
    27181 gtcgcgatca tcgccgcgga cgccttcaag atcggcctgg accggccgca cgccccgcgc
    27241 gtgagcctcg acgacctggt gctgttccgg gagacctggc ggctgccggc cgccggaacg
    27301 gaactgcccg acaaggccga gcgggagcgc gactatctcg ccgtccgccg gtgggtggcc
    27361 gaacacgccc tgcccgacct gctcttcgtc aagttccccg aggagaccaa gccgtccctc
    27421 gtcgacttca ccagcccgac gctggtgctg tccttcgcca acctcgtccg ggccgcgcgc
    27481 cggctcgacc ccgacgccgt catcaccctc agcgagccgc tgccggctcc ggaggactcc
    27541 tggcttccgg acgccgacgg cgagcgcttc gtcagcgaac tgcggctcca gatcagcaga
    27601 aaggtgccgg aatgaccgtc ctcgcctccg acggcgcggc cctcgcggtc cgtgccaccc
    27661 gcacccggga ccccgacatc gtcgcgacga tcggcggcac cccgctggtc gccctcgacc
    27721 gcctgttccc gcccgcgcgg ttccaggtgt acgccaagtg cgagcgcttc aacccgggcg
    27781 gctccatcaa ggaccgcgcc gccaagtcga tgatcgagca cgccatcagg gcggggaagc
    27841 tcgtccccgg cgtctccacg gtcgtggagt cctcctccgg caacctgggc atcgccctcg
    27901 cccagctgtg caacttctac cggctgaacc tgatctgcgt gatcgacccg cgcaccaccc
    27961 cgcagaacgc cgccatcatg cgggcgtacg gcgccagggt cgaggtggtc gaccgcgacc
    28021 cggccaccgg cgagtacctg ccggcccgga tcgagcgggt gcgctcgctc ctcgagagcg
    28081 tcccggacgc ctactggccc aaccagtacg ccaacgagca caactcccgg gcccaccacc
    28141 acacgatgcg ggagatccac gaggccctgc cgggcggccc cgaccacctg ttcctcgcgg
    28201 ccggcacgac cgggacgctg cgcggctgcg ccgagtacat ccgcgaccac ggcctggcca
    28261 cgaacgtggt ggcggtggac gcggtcggca gcgtgatctt cggaccgccg gagccgtggg
    28321 agctcaccca ccggcgcacg atccccggtc acggggcggc ggtcgtgccg ccgctgctgc
    28381 ggccgggcct cgcggaccgg atcgtcaagg tgaccgatct ggactgcgta cgcggctgcc
    28441 ggcagctgct cgcccaggag tccatcctgg ccggcggctc ctcgggcgcc gtcgtggccg
    28501 ccctccagca cgcggcgtcc tggatcgaac cgggcgcgac ctgcgtagcc gtccttcccg
    28561 acggcggcga ccgctacctc gacaccgtct actcggactc ctgggtcgag gaccgcttca
    28621 aggacttccc gctacccgac cacacccgtc tcgaccaccc cggtcccgac accaccgatc
    28681 acgaaaggag tgagtcatga ggatcctcgg tcgcgacgac gtcgcagtgg ccctgaaggg
    28741 cctcggaccc gccgtcctcg acgcggtccg cagcgcctac gtgctgcacg gccagggcca
    28801 ctcgcaggtg ccgttctcca gcttcctgcg cccgccgcgg cccgccggct cgcgcatcat
    28861 ctccctgccc gcctacctgg gcggccccga gccggtgatg ggcctgaagt ggatctcgtc
    28921 cttcccggcc aacgtcgagc agggcctcca gcgggcctcc tccgtccagg tgctcaacga
    28981 cctcgacacc ggctatccgc aggccctgct ggaaggcagc cagatctcgt cctcccggac
    29041 ggcggcgagc gccgccctcg ccagcggcgc gctgcacggt tcccgtccgg tgcgcacggc
    29101 cgggttcatc ggctgcggca cgatcaacca gcgggtcctc gccttcctca ccctgaccca
    29161 ccccgagctc gagaccgtgg tgctccagga cgtcgtcccg ggccgtgccg aggtgttcgc
    29221 cgccgaactg gagtgcgagt acccggggat caccttccgc accggcgaca tcgccgaggc
    29281 gctcggagcc gagacggtga gcatcgcgac caccgactcg acgtactggc tcgacctggc
    29341 cgcccacccc gaccgcccgt cccgccaggt gatcctgcac ctgtcgctgc gcgacctgag
    29401 caccgactcg gtgctcggcg cgtacaacgt ggtcgacgac atcgagcacg ccgtccgtga
    29461 gcggacctcc ctgcacaggg ccgaacagga gaccgggcac cgggagttcg tgcacgccga
    29521 gatcgccggc gtgctgggct gctccgagcc gccggccacg gaccgcacga tcgtcttctc
    29581 gcccttcggg ctcggcatcc tcgacctcgc ggtcgcccag gcggtcctca aggccgccac
    29641 cgcggccggc ctcggcaccg aggccgcggg gttcgacccg ggcagccacc gggtcaccgc
    29701 ggcgatggcg gggagggccg catgagcacc ttcttcgccg agggcaccaa ggccctcgtc
    29761 accggcgcct cgcgcggcat cggcgcggcg atcgcgctca ccctggccga gcacggctgc
    29821 gacgtggccc tcaactaccg ctccaacgag gcgaaggccg aggaggtcgc cgagcggatc
    29881 cgcgcactcg gccgggaggc cctgccggtc cgcgcggacg tctccgacga ggcccaggtc
    29941 gccgcgatgt acaagcagct gaaggcggcc tgggggcgtc tcgacgtagc cgtcctcaac
    30001 tccggtgtca ccgccgacgg tcacctggcc gccatgagct ccgccaagtg gcaggaggtc
    30061 atcggcacca acctgaccgg caccttctac accgcccgcg aggccaccaa gcagatgtac
    30121 gcgagcggcg gcgcgatcgt cttcatcgcc tccaccagcg gcatcgccgg ccgggccggt
    30181 caggccaact acgccgccag taagggcggg gtgatcgcca tggccaagac gctgtcgtac
    30241 gaggtcgccc cgcgcggtat ccgggtcaac gtcgtcgcgc ccggcttcat cgacaccgac
    30301 atggtcaaga aggtgccgcc ggcccacatg aaggaggcgc tccaggtcat cccgatgggg
    30361 cgcatgggca ccgcggccga ggtggcccag gcggccgcct tcctggccgc ccccgccgcc
    30421 tcctacatca ccggcaaggt gctcaccgtc gacggcggaa tgatccccaa ctagccacca
    30481 gagcatggca atcgccatcg cacggcaatc gcacagcact catcccctct gtgaaaggaa
    30541 cgcaccgtgt ccgtcgccac cttcgaggac atccgtaccc aggccgagac ccgcctggcg
    30601 aagaacatga aggtcaagtc gatgatcatc gaccgcctgg gcctggacgt cgagcccgcc
    30661 gtcgtctccg acaaccagcc gctgttcggc cgcggtctgg agatggactc gctggacacc
    30721 ctggagatcg tcgtcatggt caacaacgag tacgacgtgc tgatcagcga cgacgacttc
    30781 gaggccttcg gctccatcaa cgccctggtc gacttcatcg aagcccgcga ggtctgagca
    30841 tgaccatcgc ctccgaggcc cccgccaggc cccagcagaa gcacagttac tcctccgacg
    30901 acatcaagcg gatgctgccg caccgctggc cgatgctgat gatcgaccgt gcctacgacg
    30961 tcgtccccgg cgtctcgggc cgcggcgtga agagcgtctc ggtgaacgag cccttcttcg
    31021 ccgggcacta ccccgaccac tcgatcatgc cgggcgtgat gatcgtcgag gcgatggccc
    31081 agctggtggc cgtcgtgtac gtcgccgagc tcgtcgaggc ggccgcggca gccgcggccg
    31141 ccggtgcgcc cgagggcggc gacccctccg agagcgtcgg ctacctcggg tccatcagct
    31201 cgatgaagtt ctcccggctc gtcgtccccg gcgaccagct gaccctggac gccaagctcg
    31261 gccagcggct gggcggcctg cggcaggtgt cggtgcgggc gagcgtcggc tcggaactgg
    31321 ccgccgccgg ctccctgatc gtcaccaccg gccgcaaggc ctgaccccgc tgcacgggtc
    31381 ccaccgaaga accctcgaag aaaaggaggt gaggcatgtc catcacgatc cgcccgtacc
    31441 aggagggcga cgcgcacgac atcgcggcgc tctacaaccg ccaccgcgac aaccccaacc
    31501 cggtggcggg cggcatcacc ggtgacgagc tggagcgcga gctggccgaa cgggacacgg
    31561 gaacgttcct cgtggccgtg gacggcgggc gtgtggtggg caccttcggc ctgttccaca
    31621 acaccggccg gcgctccgcc cgcgccggtg agctgatcgc cgacatgttc ttcgtcgccc
    31681 ccgcctaccg caacggcgtc atcaccggcc ggctgttcac ggaggccgtc gagtggatgg
    31741 tgcagtccgg ctgcctggtg ctccggctca ccgtcaaccc ggccaacagc gtcgcgttca
    31801 agctctaccg gcgcgtcggc tgcgtctccg tggggcagac cgtgcccggc gaggacggca
    31861 acgtcgaact gcacaactac atcccgctgg tcctgcgcag cgtgttcgcg gacctggggc
    31921 cggaggtcag gtcggccctc gggggactga acagcttcgg cacggtcacc gaggcccggg
    31981 acgacgaact gcgctccgac gtccggctgg tggacggcgt ccgcacggtc gactaccagc
    32041 tggcgctggg cgggttccgg atcaccgcga gcgtcgacgt cgaccgcggc gtcgtccgcg
    32101 aggcggaggt caccggaccc gacggcaccg cccgcgcgct gcggctcacc gaaccgccgt
    32161 accacgtgcg cgcaccgagg cggccggagc cgcaccggtt cggctccggg ggactggtct
    32221 gcgaggtgga cggcgacgac ggcacgctgt cggtgctggc cgagggccac cacggcccgc
    32281 tgttcgtctc cacctggccc agctgccggg ccgaccgccc ggcgggctgg cgcgagggcg
    32341 agccccgcga cctggacatc gtcgccgtcg agaacggggt ccgggtcacc gagcggtgcg
    32401 gcgaggacga ggtcgtcggc accgtcaccc tcaccgaggg caccctgcgg caggacttca
    32461 ccttcaccag ccgccccggc cggatcttcc agacggtcgg actgcggcag ggcaccttcg
    32521 tccacccgga cggcgagcgc cacccgatcg gtctgggcct cggcgtccgc gacgcctcgg
    32581 aggcggtcgc cgcctcccag gtggtcccgg ccggcaccga gctcgcctgg cggtcgacct
    32641 cgtggggcat cgggctgccg gtccgcgagc cggtccggct gatccacagc gccctgctgg
    32701 agcgcggcct ggcggccggc ccggacggag tggcccggct gcggaccgac ttccacccgg
    32761 cgaccgcgag gacggacgcg ggaaccgaca caacggccga cgcggggacc gacacaacga
    32821 ccgacgctgc gacggaagct gcgaccgagg ccgcggccga tgctgcgacc gaaccggtga
    32881 ccgaagcggg gacggaagcg aagaccgaag ccgaacgacc cgcccgtacc gtcccgaagc
    32941 cgggtgccgt ccgccggctg gaactcaccg cctccgccgc cggagtcacc tcctggaagg
    33001 agggcaccac caaggtcctg cgcagcccgt acccgcgcac ccgggtcttc ggctacaacc
    33061 cccgctggtc ggccggcatg tgggtcaccg cggagagcag ccggttcggc cgcgcgagcg
    33121 gtctcggctg gggcgtgcgg tcggccgcct gggaggagaa gcacccgctc ggcctgttcg
    33181 ccccgcgcga gcggatcggc tgggaactga ccgcccccga aaacaccgcc gagccggtcc
    33241 gggccgacat ccaggccccg gacagcgagg aggagatcgt cctctggctc accccgaaca
    33301 ccccgcgcga gaccaccgtg ctgctcgact cggccggcac ccggtgggag ctcggctcgg
    33361 ccggcttccg tcaggtctgg gccaccgcgg ccaccgtacg actcgccgac ggcagctggc
    33421 tcgactgccg gcccgccgac ggcgcgtgcc cgcaggccga actcgtcctg cgtacgaccc
    33481 cttccggcct gctgatcggc tgcgtgtccc cggcccgccg gccgagtgcc tggcagctgg
    33541 ccgtgcacga cggacccacc cggtcctgaa ccaccgtcat ccagctccga ccaccgtcct
    33601 tcgagaggaa accccacacc atgaccacca ccaccgtctc cgccgcccgt accgcctcgg
    33661 acgactacgc caccgtgcgc accaccatcg gcgcctaccg gatcgacgcc ccgctggtcc
    33721 gcgtctcggg cgacgagcgg ctggcactgc tcgaccagtt cctggccaag tcgggcgact
    33781 tcgtcgagcc ggactccgtc cgcgaggtgc tggccctgaa cgccgacggc accccgttcg
    33841 cgatcctgct gcacttcgag atcggcgagg acgcctggct gctgccccgc acccgggtga
    33901 ccgccgacga gctgcgcggc tacctcgacg gcctggacgt ccccgagggc gtggaggtcg
    33961 acatcgagcc ggagggctgg gccgccacgg cgttcgaggg cccgacggcc tggtcggtcg
    34021 cggcccgctt cgtcgacttc gacatctcgg gcctgaccct gcacgccgtc accgagtccg
    34081 cgctgcccga cgacccggcc gcactcgccc acctggcccg cgtcggcacc acgggcgagt
    34141 acggctacct gctcctcagc aacgcccccg aggccgccca ccgggccgtg ctggccgcgg
    34201 tccaggagga aggcggcgcg ccggtcggcg ccgaggggct cgcccgggtc caggccgagg
    34261 ccggcatggc cgtctacgcc gccggtttcg ccggtctttc ggtcgacgag gccgacctgt
    34321 cctggatgat cgactggaac cggatcggcg agttccgcgg ctccgacgac ctggtcaggc
    34381 ccaccgccga gacggcccgg ctgactgccc tggccgcccc cgccgacagc cggttcacgg
    34441 ccggcacgca ggtgacggcg gccggccggg agatcggcac ggtcctgtgg caggcgccct
    34501 ccgccaaccc ggaggaggag ctcgtcttcg ccctcctgga cgccccgttc tgggtctccg
    34561 gtctcgaact ggccgccccg gacgagcagg ccgccgagcg cccgctgcgc accgtgaccc
    34621 tgccccgtgt catcgcccgc tccctcacca cccggatcgc ctgatgtcca cgccgagaat
    34681 cgccctgacg ggcctgggac tcatcaccgg tgccggtgac gacgtcgaga agggctggtc
    34741 gtccatcgcg tccggcacct ccggcatccg caccaacacc ctcatggaca cctccgagct
    34801 gctgaccgag tgggccggga tggtcaccgg cgagcagccg gccgacgtcg accgctgcta
    34861 cgccctcgcc gccaccgcca tccgggaggc cctggagagc agcgggctcg acctggacac
    34921 cgtcgaccgg gaccgggtcg cggtcgtggt cggctccagc ctgggcgcca tgccgacgct
    34981 ggagagcgtc cacgcggacc tcgtccacga gggcaagctg gacgcggagc gggcggccgc
    35041 cgtccaactg ccctgtgtcg gtgactacat cgccgccgag ttcgacctgc gcggcccgcg
    35101 cgtggtcctg tccaacgcct gcgcggccag cgccgtggcc ctcggctacg cggccgagct
    35161 gctgtggaag ggggacgtcg accacgtcat ctgcggcggt gtcgaccccc tcgcctcgct
    35221 ctccgcgtac gggttcagcg ccctgggcgc gctcgacccg gagccgtgct cgccgatgtc
    35281 ggcgtccacg ggcctgaccc tcggggaggg ggccgggttc atggtcctgg agtcggcgga
    35341 ccgcgccgcc tcccggggcg cccgcgtcct cgccgagctg ggcggctacg gcctctcctg
    35401 cgacggctac caccagaccg ctcccgaccc gagcggcaag ggcgcctgcg ccgccatggc
    35461 ccaggccctg gacacggcgg ggctgacccc gcaggacgtc gactacctca acctgcacgg
    35521 cacgggtacc ccggcgaacg acgcctccga accgaaggcg gtgaagctgc tgttcggctc
    35581 ctcggtgccg ccggccagct ccaccaagtc gatcctcggc cacaccctcg gcgcggccgg
    35641 ggcggtcgag gcggtcgtca gcaccctggc catcgaccgc ggcacgctgc cgccgaccgt
    35701 caacacccgg ggcgtggccc agccgttcgg cctggacgtc atcccggaca ccggccgcgc
    35761 cgggacccgg cccgaggtgg tcatctccaa ctccttcgcc ttcggcggca acaacgcctc
    35821 cgtcgtcctc aaccggccgg gccgcccgag ctcggccccg cgccgcaccg agcaggtcca
    35881 cgaggtcgtc gtcaccggag tcgctgggct ggcgggcggc gcgggcaaca ccgccgacct
    35941 ggtggccgcc ctcgacggcg agcgcgcctg cttcaccgcc accgaacacg tccggggcgt
    36001 gggcgaggtg ccggtcggcc gggtggacgt caagtcggcg tcccggggca tcaacccgag
    36061 ccgggcccgc cggatggacc cgctcagcct gctggccgcc gccgccgtcg ccgacctcta
    36121 cggccggcac ggcaagccct cgcgggccga ggccgagggc acgggcatcg tcttcgccac
    36181 cggctacggg ccggtcacct cggtcctgca gttccacaag ggcgtcctcc agcagggcat
    36241 cagcggcgcc aacccggcgc tgttcgccaa caccgtggtc aacgcggccg ccggccacgt
    36301 ggcgatgctg caccgctacc gcggctacac cgcgacgatc gccaacggcg gcacgagctc
    36361 cgtcctggcg ctccagctcg ccgcccgggt catcgcgcgc ggcatggcgg accggatcat
    36421 ggtggtgatc gccgacgagt tccccgagca ggcgctcgcc acccaggccg gcctccccgg
    36481 ctacgcgcgc tccggaccgg tggtccccgg cggccgcagc ggcatggtgc tcagcgaggg
    36541 cgcggcggcc gtccttctgg agagcgagcg gtcggcctcg tcccggggcg cggacgtcct
    36601 ggcgaaggtg cgcggttatg gggcctccgg cgaaccggcc gggatcggcc gcatcggccg
    36661 cgacggcgag gcctgggcgc gggcgctgcg cggtgcgatg gccgaggccc gggtcacgcc
    36721 cgacgagatc gacaccgtcg tctcggcggc ctccggctac agcctggtgg acaccgccca
    36781 gtcccgggcc ctgcgcctcg cgggcctcct cgaccgcccg acgatcaccc ccaaggccct
    36841 gctgggggag acctacggca gcgcgggcgc cctgggactg gtggcggcgc tgaccgcccc
    36901 gacccggcag ggcaggctgc tgctctccag cttcgcctac ggcggcagct acgcggcggc
    36961 cgtgttcgac acggaggcgt gatgggggcg ctgctggggc tggtgatgga tccggtgctg
    37021 cgcggcgcgg cgcgacctgc cccgatcgac tgcctggtca cccaccacgc ccaccttccg
    37081 cgcgaccgca tgggccgccg cctcgacgcg tccggccgtt cgctgatcat cgaggccgtc
    37141 gcccgggtgc acggcctcga catcggggcg cgggacctca cgagggacgt ccacaagcgc
    37201 tggcacgtcc cggcccacgg gctcaccgcc tcggtcgcgc actgcgacgg ctggagcgcc
    37261 gtggccctgt cggccggccc ggtgcacatc ggggtggacc tccaggacga acgggaccgg
    37321 ccggccgcca tgcggtggct cggcaccctg ctcggccgcc gccgccccgc cgagatccgg
    37381 gacttcgccg agtgcgaggc gctcatcaag gcctcgcacg tcaccaagga gaccttcgcc
    37441 ggggtccggc tgcccgcgtg gcggccgggc tggcggccca ccaacgtggg cgcgtaccgg
    37501 gtgcgttcga cgacggtggc cccggcgatg cacctggccc tcgcggccga cgcccccgcc
    37561 cccgtccgtc tgcacacctc gccccaggag ccggcatgac agccacagcg gccgctgtac
    37621 ggccctacac ccgccgtatc tcgcagatcg agcgcggcta cctgaacgcc gcggccaccg
    37681 gcaccccgca gctgatccag atgatcgtgg agggcgaggg ccgcatcgac cccgacgcgc
    37741 tgcgggacgc ggtgcggtcc gccaccctcg cgagtcccgg cctcgcggtg cggcgccggg
    37801 gtgcgggctg gcgcgccgac ggcccgctgc cgccggtcgt cgaactcccc ggcggcgacg
    37861 ccttcgacgc ccccttcttc caccgcgacc tggacgtcgt ctccggaccg gtctgcgagg
    37921 tcggactcgt cgcggggccg tcgacccggc tggtcgtccg ggccagccac atcgtcaccg
    37981 acggccgcgg gctccggcag tggatcgccg acgtgttccg ggtgctgcgc ggcgaggagc
    38041 cggtcggcgc cgcgtccgtc gtcgacgaca cccacttccg gacggccgcc gggaaggtgc
    38101 cgcccgccga gccgcctgcc cggctggacg gcctgcccgc gatcctcggc gacggaccgg
    38161 ccgacggcac cccgctctgg atacggcgcc gggtgcgggc ggccccgtcg gcggtcaccg
    38221 cccgggtggc cgccgccctc tcccgccgtc tcggcggcga gacgggccgg ctgatcgtgc
    38281 cggtggacct gcgccgccac gaccgcacgg tccgctccac cgccaacctc acctcccggc
    38341 tggtgctgga cctgcaccgg gacgacagct ggaagcggct gcacggccgg atcgtccggg
    38401 ctctgctcgg caagcacgag gtggccgcgc tggatgggga cttcctgcgc agcaacccct
    38461 tcgccaactc gctgcgcgag gcgcaggaac tggacggcac ccggttcccg tgcacggcga
    38521 tcgtctccga ccacggccgg atcgacaccg ccgaactgcg caccgacggg tttcacccga
    38581 ccggcttctc cacgctgccg atgctcgtgc cctacgccga gatgttcctg agcacctgcc
    38641 aggtcggcga cgagaccgaa ctgaccctgt cctgccgcag ccgccccggc gcacgcgagg
    38701 cggccgaggt ggtcctcgac gacatcgagc acgcgctgac cgccccgaac tgacccggcc
    38761 cacggccctg ccgactccac ggccctgccg actccacggc ctgctgactc cacggcctgc
    38821 tgactccgcc gccctggcga gtccatgccc tggcgag
//