LOCUS       NZ_LMEQ01000007        41185 bp    DNA     linear   CON 07-JUN-2024
DEFINITION  Streptomyces sp. Root1310 contig_15, whole genome shotgun sequence.
ACCESSION   NZ_LMEQ01000007
VERSION     NZ_LMEQ01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root1310
  ORGANISM  Streptomyces sp. Root1310
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 225710)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 225710)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140604
            Assembly Name                     :: Root1310
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001426425.1-RS_2024_06_07
            Annotation Date                   :: 06/07/2024 02:14:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,470
            CDSs (total)                      :: 8,385
            Genes (coding)                    :: 8,123
            CDSs (with protein)               :: 8,123
            Genes (RNA)                       :: 85
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 262
            CDSs (without protein)            :: 262
            Pseudo Genes (ambiguous residues) :: 0 of 262
            Pseudo Genes (frameshifted)       :: 98 of 262
            Pseudo Genes (incomplete)         :: 219 of 262
            Pseudo Genes (internal stop)      :: 20 of 262
            Pseudo Genes (multiple problems)  :: 64 of 262
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:32:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 147123
            Orig. end                         :: 188308
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMEQ01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..41185
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41185
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41185
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21185](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21185)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            452..1051
                     /locus_tag="ASD48_RS15975"
                     /old_locus_tag="ASD48_37935"
     CDS             452..1051
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="ASD48_RS15975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_37935"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_057602297.1"
                     /transl_table=11
                     /translation="MGLPEEQAGQDGNLRRTLLDAALGVFTERGYADAGLTEIATRCGI
                     PVGSLFQHYGGKRGLYLALWEEFREEQERRTATTLTAERNRGVDDPVALFVAGARAYLE
                     GAWDHRRLGRLLVEDDGPAGFDALRRQWDRAWVRRNARLLEIDERRRAGRVRVSVLTTV
                     IGGAARELGDCGDETEAREIVDEVCGILIHLSAAPG"
     gene            complement(1296..2078)
                     /locus_tag="ASD48_RS15980"
                     /old_locus_tag="ASD48_37940"
     CDS             complement(1296..2078)
                     /NRPS_PKS="Domain: PKS_KR (9-109). E-value: 7.6e-08. Score:
                     24.4. Matches aSDomain:
                     nrpspksdomains_ASD48_RS15980_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982818.1"
                     /locus_tag="ASD48_RS15980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_37940"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_057602298.1"
                     /sec_met_domain="adh_short_C2 (E-value: 2.4e-34, bitscore:
                     112.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGLDLTGRTAVVTGASRGIGLAIAQAIAAAGANVVLTSRSQEAA
                     DAAAAQVGGTAIGVGAHAVDEEAARRCVDLTRERFGSLDILVNNAGTNPAFGPVIDQDH
                     ARFAKTFDVNLWAPLLWTGLATRAWMGEHGGAVVNTASVGGMTFEANIGLYNASKGALI
                     HLTKQLALELSPKVRVNAVAPGVVRTKLAEALWKDHEETLSAATALGRIGEPTDIASAV
                     AFLVSDAASWITGETMVIDGGQLLGDPLPFRQEAGAGA"
     aSDomain        complement(1752..2051)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS15980_PKS_KR.1"
                     /evalue="7.60E-08"
                     /label="ASD48_RS15980_PKS_KR.1"
                     /locus_tag="ASD48_RS15980"
                     /protein_end="109"
                     /protein_start="9"
                     /score="24.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TAVVTGASRGIGLAIAQAIAAAGANVVLTSRSQEAADAAAAQVGG
                     TAIGVGAHAVDEEAARRCVDLTRERFGSLDILVNNAGTNPAFGPVIDQDHARFAK"
     CDS_motif       complement(1956..2045)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS15980_0001"
                     /evalue="7.10E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="ASD48_RS15980"
                     /protein_end="41"
                     /protein_start="11"
                     /score="25.1"
                     /tool="antismash"
                     /translation="VVTGASRGIGLAIAQAIAAAGANVVLTSRS"
     gene            complement(2080..3348)
                     /locus_tag="ASD48_RS15985"
                     /old_locus_tag="ASD48_37945"
     CDS             complement(2080..3348)
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982819.1"
                     /locus_tag="ASD48_RS15985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_37945"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_057602299.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.1e-13, bitscore:
                     44.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 8e-19, bitscore:
                     61.2, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 7.1e-37, bitscore:
                     120.4, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLFEMRDRAKKYQADLLEFMDAHVYPAEAVYHEQMRASGDPHFH
                     PPIIEELKAEARKRGLWNLFHPHPEWGPGLTNLEYAPLAEIMGRSHIAPEACNCNAPDT
                     GNMEVLTLFGSDEHKEKYLKPLLDGTMASAFAMTEPRVASSDATNIELRMERDGDAYVL
                     NGRKWFASNALHRNCKVLIVMGKTDPSAAPHRQQSMMVVPIDAPGITVMRGLPVFGYQD
                     REGHAEIDFTDVRVPAKDVLKGEGEGFAISQARLGPGRIHHCMRAIGAAERALELMCRR
                     AQSRLTFGSPVAERSNIQDWIAEARIDIEMIRLLTLKAAYLMDTVGNKEARTEIAAIKV
                     AAPNIALKIIDRAIQVHGAAGVTEDFPLAMMYAQLRTLRLADGPDEVHKRAIARHELRR
                     YRDGAATAASGTNAPGGHEAGVN"
     gene            complement(3605..4297)
                     /locus_tag="ASD48_RS15990"
                     /old_locus_tag="ASD48_37950"
     CDS             complement(3605..4297)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994676.1"
                     /locus_tag="ASD48_RS15990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_37950"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_057602300.1"
                     /transl_table=11
                     /translation="MDSRAAGEIDGEKVPPMAPLAPLREPPATKRGARTRAALVTAARK
                     VFERDGYLDTRLTDITKEARCAAGSFYTYFANKEEVLAAVLLEAQEDMLHPGMGRVQDT
                     DDPFAVLEASNRAYLEAYKRNAKLMALLEQVAQVEPEFREFRSRRGDAFIRRNARGIAD
                     LQARGVADQEVDPMMASRALSGMVSVMAYNAFVLGERQEEGAPVDFEELVSTVTRLWAN
                     ALRFPGHC"
     gene            complement(4377..5003)
                     /locus_tag="ASD48_RS15995"
                     /old_locus_tag="ASD48_37955"
     CDS             complement(4377..5003)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982821.1"
                     /locus_tag="ASD48_RS15995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_37955"
                     /product="HAD family phosphatase"
                     /protein_id="WP_057602301.1"
                     /sec_met_domain="HAD_2 (E-value: 7.8e-10, bitscore: 32.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDRARTAVLVDFGGVITSSVLQAFTDFGASLGGDPRLPLDLLGRD
                     QPSRALLADHECGRIGAEDFERGFAERLRVHGADVQAEGLTARMQAGMSIDQDMLALLG
                     DLRAAGRPVALVSNAFGTGTYDGVDLAAVADAVVISAEVGIRKPSRRIYAIACERLGVD
                     PGEAVMIDDLQQNLDGAARIGIGGVLHTSAADTRRRLAERFGITA"
     misc_feature    complement(5009..5023)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.02"
                     /tool="antismash"
     misc_feature    5020..5035
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.25"
                     /tool="antismash"
     gene            complement(5095..6294)
                     /locus_tag="ASD48_RS16000"
                     /old_locus_tag="ASD48_37960"
     CDS             complement(5095..6294)
                     /EC_number="2.3.1.16"
                     /GO_function="GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982822.1"
                     /locus_tag="ASD48_RS16000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_37960"
                     /product="acetyl-CoA C-acyltransferase"
                     /protein_id="WP_057602302.1"
                     /transl_table=11
                     /translation="MREAVIVSTARTPIGKAYRGAFNDTQAQELAAHALSHAVQRAGLE
                     GGEVEDVVFGCAVQQGSSGFNVARQAALRAGLPDLVSGMTIDRQCSSGLMAIATAAKQI
                     VTDGMQVAVGGGVESISLVQNDHMNTHRMADPWLVEHQPGIYMPMLQTAEIVAERYGVS
                     RERQDEFALVSQQRTAAAQEAGRFDREIVALTSTKKVLDKESGELRDEEVTLARDEGNR
                     ASTTLDGLAGLAPVLPDGQVSARSSVTAGNSSQLSDGASASVLMEAREAERRGLEPLGV
                     YRGMAVAGCGPDEMGIGPVFAIPKLLKQHDLTIDDIGLWELNEAFASQALYCRDELHID
                     PERFNVDGGAISVGHPYGMTGARLVGHALVEGKRRGVRYVVISMCVGGGMGAAGLFEVV
                     "
     misc_feature    complement(6481..6494)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.75"
                     /tool="antismash"
     gene            6740..6940
                     /locus_tag="ASD48_RS41295"
     CDS             6740..6940
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012770.4"
                     /locus_tag="ASD48_RS41295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_157880627.1"
                     /sec_met_domain="PF00561 (E-value: 5.9e-07, bitscore: 22.8,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAPDQRDHSPGARPQRPEDYRISLLVDDAVAVTEERGLATFGLVG
                     HGWGGAVAWWTAHTYPGRVAP"
     gene            8241..8582
                     /locus_tag="ASD48_RS16010"
                     /old_locus_tag="ASD48_37970"
     CDS             8241..8582
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013625.4"
                     /locus_tag="ASD48_RS16010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_37970"
                     /product="peptidoglycan-binding domain-containing protein"
                     /protein_id="WP_057602364.1"
                     /transl_table=11
                     /translation="METPLPLTPAPEDPSPRAPGRPDPSQPGTPDPRLPEIPGTGVLRQ
                     GDSGHGVYELQVRLLQIPDIYSGGPIDGRYDTRLRAAVTLFQEQYGIRGDESGVYGDNT
                     RFALMLRTK"
     gene            complement(8677..10461)
                     /locus_tag="ASD48_RS16015"
                     /old_locus_tag="ASD48_37975"
     CDS             complement(8677..10461)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994937.1"
                     /locus_tag="ASD48_RS16015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_37975"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_057602303.1"
                     /transl_table=11
                     /translation="MPRQQPGRSLRAAKELYLEVTKDPSARPLVVASWHRSMEYEVMPG
                     SLDAPYLDNPNLDSHLARAALPILDRLHEQLADDPVSTMVTDRNGVVLSRKVSHEGLTT
                     NLNRVHLAPGHVFAERYVGTNGIGTALASGRPVMIAGTEHYVEALRDFRCAAVPILHPT
                     RRTLLGAFNLTTIRQGSDGMLMAFARSVAAQIEAEIAAITSRRERALFHDYMEACSSAR
                     PGPVLALNRDVVMMNEQLSAAVAGPDHHALLDHAREIADHPRLEGTRSIALPSGRVAEL
                     RVSRCRREDRDAGAVLRVRLIGRSQPTHAVSAAPARPDLGLVGSSPQWLRAVADSETAF
                     VAGTWLNLLGEAGVGKRTLVEALHRAHGAGRRLELTQAPLSDAPAVTERWLHDIGELLG
                     VPSNVLVLSDVHLLGDRLRQRLANLLVRLDGSAPGQLVVTGQPSLVGADDQLDQRCGAS
                     VEVPPLRHRYGDTEHLARFFLRKYRPSGESRLSPDALTVLQRCPWPENVRQLESVIRGL
                     ARRPSGRMIHVEDLPPECRVSSNKVLTTIEALERDAIMRGLVNRDSNVQRTAQDLGISR
                     ATMYRKMRRYGIVPSSLT"
     misc_feature    10447..10464
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.95"
                     /tool="antismash"
     misc_feature    complement(10506..10519)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.11"
                     /tool="antismash"
     misc_feature    complement(10540..10554)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.24"
                     /tool="antismash"
     gene            10644..11669
                     /locus_tag="ASD48_RS16020"
                     /old_locus_tag="ASD48_37980"
     CDS             10644..11669
                     /NRPS_PKS="Domain: PKS_ER (24-267). E-value: 9.4e-12.
                     Score: 36.6. Matches aSDomain:
                     nrpspksdomains_ASD48_RS16020_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978606.1"
                     /locus_tag="ASD48_RS16020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_37980"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_057602304.1"
                     /sec_met_domain="ADH_N (E-value: 1.1e-34, bitscore: 112.2,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.9e-23, bitscore:
                     74.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAVQVIEYDEPPVLVDVPDPQITGPLDVIVKIGGAGVCRTDLHI
                     LEGQWKEKSGVALPYTIGHENAGWVAEVGQAVTNVKVGDPVILHPLVTCGLCRACRDGD
                     DVHCMNSAFPGIDADGGYAEYLKTSARSVVPLAPSLEPASVAALADAGLTAYHAVAKAA
                     RVLRPGDKAVVIGAGGLGHIGIQVLRALSPVEMIVIDRSPEALALAEVLGADHTLVADG
                     SETDRVRDLTGGHGAEAVLDFVGEGGAVETGVACLRRNGNYYVIGYGGHLHVPTIDVIS
                     TEINFIGNLVGSYNDLSELMVLAARDKVTLHTQRYPLASFRQALDDLDTGAVRGRAILI
                     P"
     aSDomain        10716..11444
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS16020_PKS_ER.1"
                     /evalue="9.40E-12"
                     /label="ASD48_RS16020_PKS_ER.1"
                     /locus_tag="ASD48_RS16020"
                     /protein_end="267"
                     /protein_start="24"
                     /score="36.6"
                     /tool="antismash"
                     /translation="GPLDVIVKIGGAGVCRTDLHILEGQWKEKSGVALPYTIGHENAGW
                     VAEVGQAVTNVKVGDPVILHPLVTCGLCRACRDGDDVHCMNSAFPGIDADGGYAEYLKT
                     SARSVVPLAPSLEPASVAALADAGLTAYHAVAKAARVLRPGDKAVVIGAGGLGHIGIQV
                     LRALSPVEMIVIDRSPEALALAEVLGADHTLVADGSETDRVRDLTGGHGAEAVLDFVGE
                     GGAVETGVACLRRNGNYYVIG"
     gene            11688..13289
                     /locus_tag="ASD48_RS16025"
                     /old_locus_tag="ASD48_37985"
     CDS             11688..13289
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1143: sugar-binding lipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018891238.1"
                     /locus_tag="ASD48_RS16025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_37985"
                     /product="extracellular solute-binding protein"
                     /protein_id="WP_057602305.1"
                     /transl_table=11
                     /translation="MRSRPYKALVAVAAVAALTATACTAQDEAQQKPKEKTGLFKPGSE
                     ISYQKYGKDYPDTKVRDVPGPCSYDSISRKDYSGQTLKIISHAVPVIGEPTQLHAKQFE
                     DITGGKVQVVNVPFGELHQKILTPLQAGQPAYDVMFYPSLWIGDMAPYLAPVPKTYLDS
                     PGMKDVTTAYMDVATWNGKVVQYPVDGDRHYLKVRTDVLKDPERQAEYKKATGKELQVP
                     RTWAEYQEIAEFFSGKDLDGDDKANYGSAEVTKRDDLTFSAFISRAAPYVKNPDVKGGV
                     FFDLKTMKPLINTPGFVRALDDMVSARSTWAPGGANFGLGDEIFSFGGGQTLMSYSWDD
                     AFIQAQQSDSRIRNKVQAAPLPGSTEVYNRTTKSWDKKTNQAPYFTWGWTSAVAEASRH
                     QQMAFDYLCFFSNEANTALDLTIGRFGVNPYRYAHFDAEFWEKQGWDKDVAESYVRTLA
                     GMEKSTNRVFDLRVPGVNQYMSALANGVAAALAGQSSPQQALDDVAEEWSKITDQIGKD
                     KVQSAYRNVVALEDYS"
     gene            13371..14249
                     /locus_tag="ASD48_RS16030"
                     /old_locus_tag="ASD48_37990"
     CDS             13371..14249
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1067: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017949266.1"
                     /locus_tag="ASD48_RS16030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_37990"
                     /product="sugar ABC transporter permease"
                     /protein_id="WP_057602306.1"
                     /transl_table=11
                     /translation="MDGLRRHKSMFLLPGLLTLFLIIIFPLLFTIRVSFSGWNVSNPAM
                     DFIGGANYTAMLHDSRFWASVNRLILLAGGTVLIQYVIGFGMALLVWREARGRRFWRVL
                     FLVPMMTTPVVMAAIWQTIFHESLGPANDLLGMLNLPRIPWLTESGPALVALMTVEVWQ
                     WTPFMFLLLLAGLLSLPKEPFMAAAIDGAGTWRTFWKVTFPLMAPVSVAAVIIRLVEAS
                     KLSDSVYVLTSGGPGSSTETPGYYLYIQGLRDQQTGYGGAMSLTYLVLMIVTLTVVAAL
                     LTRAFKLKGDS"
     gene            14246..15091
                     /locus_tag="ASD48_RS16035"
                     /old_locus_tag="ASD48_37995"
     CDS             14246..15091
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1069: putative ABC
                     transporter permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994933.1"
                     /locus_tag="ASD48_RS16035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_37995"
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="WP_057602307.1"
                     /transl_table=11
                     /translation="MRSRLYPVFKYTVIALWACFVAGPFFWAMTTSFKNANAVQGGPTY
                     LPWVQYKPTLTGWRNIFGGAGGIDVIDPFINSAIITVAASAISLALGSLAAYALSRYRF
                     RLGFIKNSDIVFFFVSQRIMPPVVLVIPFFYLLQWGGLLDSIPGLVIVTVALLLPIAVW
                     VMVDFFNGIPREIDEMAMLDGCPPFQTFVRAILPNSLPGLTVAAMFCAVFGWNDFFFAF
                     RLTFTEVQTLPQAVVALNSSIPPWWTLSAAALFGVAPLILLALWVERLLSKGNLSGAVR
                     "
     gene            15088..16176
                     /locus_tag="ASD48_RS16040"
                     /old_locus_tag="ASD48_38000"
     CDS             15088..16176
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982835.1"
                     /locus_tag="ASD48_RS16040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38000"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_057602308.1"
                     /transl_table=11
                     /translation="MNFSATDLCLTVDGVDHLKNVTATFQPGRLHTVIGRTMAGKTTLL
                     RALAGLQKVDSGSLTRAGADFLRTPVWRRDTAMVYQQFINYPHLNVFDNVAFPLKRAGL
                     SRNEVQRRVRQSLASVGLADFEKRKPSQLSGGQQQRVAMARALARGTGILLLDEPLANL
                     DYKLREQLRDEFKALFSDQGDTIVIYTTTEPAEAMMLGDVVLVMHEGRILQTGTPQEVF
                     EHPATTAVASIINDPPMNIFAGRTEGGQVMVTGFQATHVSAHLADLPDGAYQFGLRATD
                     VSLASGGVEAEVTFVEISGSETFVHVVVGETPFVVRIEGIHDVALGDLVRLRLRPDRLF
                     AFDEQGTLVRTPSYDLASVEGR"
     gene            16178..17257
                     /locus_tag="ASD48_RS16045"
                     /old_locus_tag="ASD48_38005"
     CDS             16178..17257
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017949269.1"
                     /locus_tag="ASD48_RS16045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38005"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_057602309.1"
                     /transl_table=11
                     /translation="MAQLDIVDVGHAYTPGAEEEQWALKPLKLTFESGKTYALVGPSGC
                     GKTTLLNILSGLVRPSRGQVLFDGLDVTALPTKARNIAQVFQFPVIYKSMTVYENLAFP
                     LQCRRWDKARIAAKVQQVAEALDLHDRLRQPARGLTADDKQLISLGRGLVRDDVAAVLM
                     DEPLTVIDPQLKHSLRRKIREITEQFQPTVIYVTHDQYEAMSFAQELLVMKDGRAVQQG
                     TPEQLFEAPSSTYVGYFIGSPAMNFLALDRNDGPFELGGRTLSVAWDIPHSTTDVQVGV
                     RPEYVRVVTTPGLNTFPGRLRGVSDHGAQRVLEVEVAGQLVRAKTPREEGVPVGEEVLV
                     HLPRAKVLPYVDGRLALRS"
     misc_feature    complement(17387..17402)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.62"
                     /tool="antismash"
     misc_feature    complement(17387..17404)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.72"
                     /tool="antismash"
     gene            17780..19942
                     /locus_tag="ASD48_RS16050"
                     /old_locus_tag="ASD48_38010"
     CDS             17780..19942
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010038380.1"
                     /locus_tag="ASD48_RS16050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38010"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_057602310.1"
                     /transl_table=11
                     /translation="MDSTPSPSSSSPFDLVSSALGRYGSRGGAAAAAGPDNAAGEHTTG
                     RRAADSPAADRHDQILGVVNLDRDLRITRCNLDAAVFAGLDAAPGSLFADLLPPGDVPT
                     VTRRLRQVLEIGEAHVARIQRLRRSDGSELVVSLSILPAAAPQEGLTVSLIAMARRLHL
                     YAAETAIGTSLDIGETAQSLAESLLAWGDVAAVDLDFAVWTGEGVTDQAQGRIRLRRAA
                     LVPDRAWPEGYVTPGGDLPSDASRLLAQAVLRDDAPQAIVIPDRKAVERLLGSPRVIRA
                     LVPGDRSAGVACMPLVLDSVPPVVLGVAEVWRRADRPFRDGELFDLQELVARTAHHVDL
                     ARQHQREHTQVLALQRRLLPRTGGHTLEIASIYQPATPDSAGVGGDWVNSFPLPDGRTA
                     LVVGDVVGHGLGAAATMGQLSMEARALLSAGLAPDEVLEHLDDTVTLLDDAESGLTAGY
                     SALGSTCCIALYDPVGHHVTLASAGHLPPVLVLPDGRAAPLAVRPHPGLGVEFALREPF
                     DVHTFDAPPGSLLALYTDGLVEDPALSIDEGIARLADTVATVHPWDTLQQAARHVVSTL
                     APVRQRDDVTLLLARMIGYRKEDTATWRLPARADAPARARAHVSALLRRWDSRSDTRDD
                     VTLLVSELVTNAVRFAAGPVTVRLIRAGHVLLCEVGDTGNGRPRLGRGDLLDDAGRGLH
                     IVHRLTTRWGVRWTDTGKVVWAEVAG"
     gene            complement(20001..21185)
                     /locus_tag="ASD48_RS16055"
                     /old_locus_tag="ASD48_38015"
     CDS             complement(20001..21185)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024: chalcone and stilbene synthase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031521.1"
                     /locus_tag="ASD48_RS16055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38015"
                     /product="polyketide synthase"
                     /protein_id="WP_057602311.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 1.6e-19,
                     bitscore: 63.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAYLCPPAVIHGEHAVETSQIVAEVRDRHPHAAWAPRIDGIAAS
                     TGIETRGWMLPLETAVAPGKGSGLRDVGNGPAQEALAREGFSGQDVGRVIAALEAIPAP
                     QTVQERTAPAWEAVQSYGERAARGALQIAGLDASDVDCLITSHSTTPALPGLDIALADK
                     LALRDDVMLLPATQWACIAGTRSLALAADLVAADPDRVVLVVIAEALSTTYQPADDTIE
                     SLIVRLLFADTAVAAVVTGRPRSESVLRLDASWNHTLPGTQDLHRLETRADGTHFVMDR
                     RGPRAVQETVTAMWEWLRLRYQDDPDAWHPDVLLAHPGGTRVLEYMEQTMPDAWPSGLL
                     DYSRDSYTSGNRGGAAVFDILRRAHDAGQKPGSRAVLYAAAPGLTATALEGEWL"
     misc_feature    complement(21765..21779)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.14"
                     /tool="antismash"
     gene            21770..22729
                     /locus_tag="ASD48_RS16060"
                     /old_locus_tag="ASD48_38020"
     CDS             21770..22729
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126453.1"
                     /locus_tag="ASD48_RS16060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38020"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_057602312.1"
                     /transl_table=11
                     /translation="MTYAIRAEGLVKKYGDFTALDGVDLEVPAGKVVGVLGPNGAGKTT
                     TVRILATLMRPDGGHATVGGHDIVKDPVKVRQLIGLTGQYASVDESLSGAENLVLIGRL
                     LGLSRRDAKARAATLLEDFSLAEAARKPIATFSGGMRRRLDLAASLVGRPQVLYLDEPT
                     TGLDPHARQEVWEVVRQLVADGSTVLLTTQYLEEADQLADSITVFDKGRKVAEGRPGEL
                     KRRVGGQILQVRPTVAADVPQVAAMLTELTGHAPARDSGVLTVPADDPMIVAAVARRLD
                     GVGITADELGLRLPSLDEVFLALTGHAPAVTGDQPVAV"
     gene            22843..23658
                     /locus_tag="ASD48_RS16065"
                     /old_locus_tag="ASD48_38025"
     CDS             22843..23658
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126454.1"
                     /locus_tag="ASD48_RS16065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38025"
                     /product="ABC transporter permease"
                     /protein_id="WP_057602313.1"
                     /transl_table=11
                     /translation="MSAQPLIANAELPGRIGLAQTARHSLALAGRGVTKFMKSPIQLVD
                     VILTPIISLLMFIYLFGEAMSGGDTDGYLQLVTPGVMVMAVFQASVGIGASLCADASTG
                     IFDRFRSMPIARSSPLIGAVLADIVRYVVCLGTLVVLALIMGYRVEAGPVASLTALALL
                     VGFALSFSWISVYLGMLIKNPASVQGLMTILILPLTFASNVFVPRDDMAGWLRAWSDVN
                     PVSLVADTVRGLLNGGPVAGSLAGTFAWMAGVIAVFFPLAMHAYRKNAG"
     gene            complement(23742..26990)
                     /locus_tag="ASD48_RS16070"
                     /old_locus_tag="ASD48_38030"
     CDS             complement(23742..26990)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126455.1"
                     /locus_tag="ASD48_RS16070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38030"
                     /product="BTAD domain-containing putative transcriptional
                     regulator"
                     /protein_id="WP_242432598.1"
                     /transl_table=11
                     /translation="MVRVVLLGPIRVYADDVTPVGVGGARLRMLLARLALEAGRTVSVD
                     SLVDGLWGEQPPNDAANALQALVSRLRRALSGSAAVESAPGGYRLAVRAEDVDVHRFED
                     LTARGRRELAAGRAGQAASLLGTALGLWQGSALADVLDAPFAGPVATRLDGLRTAAAED
                     RCDAELRLGRYGEVLTDLEAAGAERPLSERVAGLRMRALSAAGRQSDALAVYEAIRERL
                     DDELGVVPSTELREVHLALLRGELETPAGRAEAAASRLPARLTSFVGRDDELSRLGRQM
                     AHSRLVTIVGPGGAGKTRLSFEAATRDRAHARGRVWFVPLAGVSAPDRLADAVLGALSS
                     TDGRLYDAGRGRPAGPVERMAGLFGSGDALLLLDNCEHLVDAAAELAAELLHQMPELRI
                     LATSREALAITGESLCHLGPLDVPTGSPEPAEAAQSPAVRLFVERAAGVRPDFTLDDMT
                     LDAVVEICRRLDGMPLALELAAAKLRSMSVEQIARRLDDRFRLLASGSRTALPRQRTLL
                     ALVEWSWDLLDEPERILARRLSVFPGGATVPALEAVCADPSLPAADIPYVLDALVEKSL
                     VDHADDGAGEPRYRMLETVRAYAARKLADAESGDALTKRYAAYFLALAEEHEPRLRTGE
                     QLRAIEVFDAEHDNLVLALRLVVDARDASLAARFAEAMFWYWGIRGMGTRLDTYLAEVA
                     GSDTAEAGEGVPAPEPVRVQDSVPVRHAVLERHSVRARSAVRAGGGERPAVEGESATAR
                     EFHPAVLLLRMSRVSFPAGAPGSGEAAERSALDSPDPWVRASAHLARDFALTEQGDLVT
                     GAESRIEALRGFEEVGDRWGLVMSLLPIGRDHSLRGEYPQAIATFERTVALSSELGTED
                     YLYLSKARLARERRRSGDLAGAFRDLHAAHRQAREQGQLRLEANILVGLANVYRRSGDL
                     AQADATLDRLEALSARRPSLRELARDLIVSTRVENRLAEGDAARARALLPEAAGALFGQ
                     GAGAALAWVAELLGGLRALEGAPEEGARSLGMSQVMRGAFDWGEPEWRELVDRIVATLG
                     EEGFRKAFEDGAAYSREDALRWLEAETLRTVPGL"
     gene            complement(27397..28350)
                     /locus_tag="ASD48_RS16075"
                     /old_locus_tag="ASD48_38035"
     CDS             complement(27397..28350)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126458.1"
                     /locus_tag="ASD48_RS16075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38035"
                     /product="hypothetical protein"
                     /protein_id="WP_057602314.1"
                     /transl_table=11
                     /translation="MRQASVLDVGCHSALLTVVRRRPGADLEPVFSRKVRLSLHETLDR
                     KGRLDKAGVRSVERAVAEAVDADPRLRGQDVFAFATSVIRDAPNCDEIIARVARTTGTR
                     LRVLAGEEEARLAYVAARRWAGPTAGRLLVLDIGGGTVEIASGSAEQPGVVHSLPLGAR
                     RITRDWLPGGIAPSPRRLAEIRQHLRRSLEGVPGLPQAEPGGRVLACSKTFEQLARLAA
                     AQSKSPRGARLLALPQLRTSVSLLADAGPSRRAKLPGISRHRAEQSLAGALIAQALMEA
                     CGVRNVEICPWSTREGLLLERLGEPPTPAGRPRAVA"
     gene            28672..29214
                     /locus_tag="ASD48_RS16080"
                     /old_locus_tag="ASD48_38040"
     CDS             28672..29214
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126459.1"
                     /locus_tag="ASD48_RS16080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38040"
                     /product="GNAT family protein"
                     /protein_id="WP_057602315.1"
                     /transl_table=11
                     /translation="MLKGDKVGLRARHEDDIPILRTELYDDVVNSSRAEGGPWRPITPG
                     SKDPRLVVDDKEQGSVKFSVVELEGGTLVGTATLWGIDNHNRAAHIGLGLLPSSRGKGY
                     GTDVVAVLCQYGFVVRGLQRLQIETLSDNAAMLRSAERNGFVREGVLRSSAWVMGEFLD
                     EVLLGLLVEDWKQDSKV"
     gene            complement(29511..30746)
                     /locus_tag="ASD48_RS16085"
                     /old_locus_tag="ASD48_38045"
     CDS             complement(29511..30746)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126460.1"
                     /locus_tag="ASD48_RS16085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38045"
                     /product="cytochrome P450"
                     /protein_id="WP_057602316.1"
                     /sec_met_domain="p450 (E-value: 1e-17, bitscore: 57.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSGTEELRIPLDPFVTDLDGESAKLRAAGPLAAVELPGGVPVWA
                     VTRHAEAKALLTDPRLVKDINVWGAWQRGEIPPDWPLIGLVNPGRSMLTVDGADHRRMR
                     GLVAQALTPRRVEAMRERITELTGRLLDRLPADAEVVDLKAEFAYPLPMYVVADLMGIE
                     ESRLPRLKVLFEKFFSTQTPPAEVVATLVELAGIMAETVAAKRAEPGDDLTSALVLASE
                     DGDRLTDEEIVSTLQLMVAAGHETTISLIVNAVVNLSAHPDQRALVLSGAVDWSAVIEE
                     TLRWSTPTSHVLIRFATEDVPVGDRVIPAGDALIVSYGAIGRDEEAHGPSAGDFDITRE
                     TRTRHISFGHGPHVCPGAALSRLEAGVALPALYARFPGLDLAVAPSALRNKPVVTQNDL
                     FELPVRLTSPTA"
     gene            complement(30749..31966)
                     /locus_tag="ASD48_RS16090"
                     /old_locus_tag="ASD48_38050"
     CDS             complement(30749..31966)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126461.1"
                     /locus_tag="ASD48_RS16090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38050"
                     /product="cytochrome P450"
                     /protein_id="WP_057602317.1"
                     /transl_table=11
                     /translation="MSTDAVPLSGPRFQTEPARLYREMRAQHGAVTPVLLDGGVPAWLV
                     LGYRELHQVTGDPVLFSRDSELWNQWDTIPGDWPLLPMIGRKQPSILYTVGERHRERAA
                     MISNALEASDPTRLRRHAERFADELIDALCAEGTADLIGQYAMLLPVRVLARLYGFSDE
                     DGPGLVTALNDMIDGRERALAGQSHLASSMGELLAARRAAPADDVVSRMLADPGGFTDE
                     EVAQDLMVMMAAGHQPTADWIGNSLRLMLTDGRFAASLFGGRNSVAEAMNEVLWEDTPS
                     QNVAGRWASRDTHLGGQHIRAGDLLILGLQAANSDPQVRPVGNELTGGNNAHFSFGHGE
                     HRCPFPAQEVAEVIARTGIEVVLDRLPDIDLDVPAESLTRRPSPWLRGLTELPVRFTPT
                     PALGGN"
     gene            complement(31963..32556)
                     /locus_tag="ASD48_RS16095"
                     /old_locus_tag="ASD48_38055"
     CDS             complement(31963..32556)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983611.1"
                     /locus_tag="ASD48_RS16095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38055"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_057602366.1"
                     /transl_table=11
                     /translation="MGATADNGLKIVVVGGFGVGKTTMVRSVSEIRPLNTEETMTRAGE
                     TVDDISEIRGKTATTVAFDFGRITLDERNVLYLFGAPGQERFWFLWDRLFSGTLGAVVL
                     VDTRRIDDSWYAIDRLERHGTPFIVACNDFGGARHAHSDVREALDLDPQVPLIDCDART
                     RESSKQVLITLVQHIQSRYAGQRAHTAASPREFV"
     gene            complement(32570..32917)
                     /locus_tag="ASD48_RS16100"
                     /old_locus_tag="ASD48_38060"
     CDS             complement(32570..32917)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018569909.1"
                     /locus_tag="ASD48_RS16100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38060"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_057602318.1"
                     /transl_table=11
                     /translation="MKRPGRDDAPDRLYTLTGGRSRSGPDSPFDLVTLVVAESDPTVGM
                     QSEHAAVLRLARAPTAVVEVAAELGLPVSITKILLSDLLAAGRVSARHPRNSALPDPDV
                     LEQVLVGLRNL"
     gene            complement(32914..33321)
                     /locus_tag="ASD48_RS16105"
                     /old_locus_tag="ASD48_38065"
     CDS             complement(32914..33321)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004986664.1"
                     /locus_tag="ASD48_RS16105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38065"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_020126464.1"
                     /transl_table=11
                     /translation="MTGTTTADEKLTWLIEGLLERTPGARHALVLSRDGLKLCRTPELT
                     VDQADQLAAIAAGIQSLSHGASVEFGDGSGGVRSSMTEFYGGTLFIVEAGEGAHLAVVT
                     TEEAEPGLVGHNMSELVEQLGEHLTAPPRTA"
     gene            complement(33318..34901)
                     /locus_tag="ASD48_RS16110"
                     /old_locus_tag="ASD48_38070"
     CDS             complement(33318..34901)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676782.1"
                     /locus_tag="ASD48_RS16110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38070"
                     /product="ATP-binding protein"
                     /protein_id="WP_057602319.1"
                     /transl_table=11
                     /translation="MTAPAPSGDRSTIRSLLPLPLLTAALSALAVVGAVTSVPESAQAL
                     VGCGGAIAAVLLCVAVTVAVHARRTTRSVRAALRTATAEAERAAQERDLQAERWRREHQ
                     RHTDATAHERARLAEEFTRERAVRAQEAEAERARLAAEVRRLSGQLDQALGDRDTAIAA
                     TANAAARMQALATGTLADLRAMEERHSDEDVLADLLHLDHRTAQAGRLADSVAVLTGAR
                     SGRRWARPISMESVLRGAMGRISGYQRIRLHSVSDTAVAGHAAEGVMHALAEVLDNAAN
                     FSPPNAEVHVYVEEVPAGAIVSVEDSGLVMSDVQLRRAEQAVSGDAGGLGGLTGTRLGL
                     AVVGRLSRKHGMKVSFRPSARGGTGVLMLIPQDILTAAPSPVRRPADPPARNAPARAPL
                     PDLGAPAPAEVATAPEEVPPQEAGADAAPQTGDGLPKRRRGRTLAAAESARAAAQSAER
                     RTDPPEDIRVRANRFGAFRQAVRAAGPAERTGGHPLPAAPDDSHTTPSPQTETAPGSST
                     PSHPEGDTTS"
     misc_feature    complement(35494..35512)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            35505..36299
                     /locus_tag="ASD48_RS16115"
                     /old_locus_tag="ASD48_38075"
     CDS             35505..36299
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-123). E-value: 2.2e-08. Score:
                     26.1. Matches aSDomain:
                     nrpspksdomains_ASD48_RS16115_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979307.1"
                     /locus_tag="ASD48_RS16115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38075"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_057602320.1"
                     /transl_table=11
                     /translation="MQIDLAGRTALVTGSTQGIGAAIAAGLARSGARVGVNGRDEQRVA
                     ESVARLATEVPGASFVPVAADVANEEGAQRVLEALPEVDILVNNLGIFGSADPLKISDD
                     EWRRYFEVNVLAAVRLTRLYLPGMTERGWGRIQYIASDSAVVIPAEMIHYGMSKTALLA
                     VGRGFAKQAAGTGVTVNSVIAGPTHTGGIEDFVYELVDRDLPWDEAQRAFMRKHRPQSL
                     LQRLIEPEEIAHMVVYLSSDQASATTGGALRVDGGYVDSILP"
     aSDomain        35529..35873
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASD48_RS16115_PKS_KR.1"
                     /evalue="2.20E-08"
                     /label="ASD48_RS16115_PKS_KR.1"
                     /locus_tag="ASD48_RS16115"
                     /protein_end="123"
                     /protein_start="8"
                     /score="26.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TALVTGSTQGIGAAIAAGLARSGARVGVNGRDEQRVAESVARLAT
                     EVPGASFVPVAADVANEEGAQRVLEALPEVDILVNNLGIFGSADPLKISDDEWRRYFEV
                     NVLAAVRLTRL"
     CDS_motif       35535..35603
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ASD48_RS16115_0001"
                     /evalue="2.80E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="ASD48_RS16115"
                     /protein_end="33"
                     /protein_start="10"
                     /score="13.6"
                     /tool="antismash"
                     /translation="LVTGSTQGIGAAIAAGLARSGAR"
     gene            complement(36380..36958)
                     /locus_tag="ASD48_RS16120"
                     /old_locus_tag="ASD48_38080"
     CDS             complement(36380..36958)
                     /GO_function="GO:0008703 -
                     5-amino-6-(5-phosphoribosylamino)uracil reductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019328167.1"
                     /locus_tag="ASD48_RS16120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38080"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_057602321.1"
                     /transl_table=11
                     /translation="MTATYTFDVFSSLDGFGAASGDWTGYWGKQGPELLDHRLGLYAEE
                     QRMVFGANTYRAFARMLASSAEESEVRDPWVTRMRSLPATVVSTTLEEPLDWPDAKLLS
                     GDAVDVVARLKEESAVPLRSHGSLSMNRALMAAGLVDRVQVTLFPVITGRTGLDPIFQG
                     SADFDLELIEHRTLDGHTQELVYRPTLHP"
     gene            complement(37059..37430)
                     /locus_tag="ASD48_RS16125"
                     /old_locus_tag="ASD48_38085"
     CDS             complement(37059..37430)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126467.1"
                     /locus_tag="ASD48_RS16125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38085"
                     /product="DUF1801 domain-containing protein"
                     /protein_id="WP_057602322.1"
                     /transl_table=11
                     /translation="MGKPQTVDEYIEGFAGQGREVLEQVRALALEAVPAASEAIKWGHP
                     AWVHPSGTILFMASGHAKHANVVFTPSTREAFDADLAGFATGKGSVKLPYGEPVPSALL
                     RRIIAFRVREHEDDGVLWM"
     gene            complement(37467..38045)
                     /locus_tag="ASD48_RS16130"
                     /old_locus_tag="ASD48_38090"
     CDS             complement(37467..38045)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126468.1"
                     /locus_tag="ASD48_RS16130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38090"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_057602323.1"
                     /transl_table=11
                     /translation="MDADLAELLDSIGPRLRALRRDRGLTLEALSEDTGISVSTLSRLE
                     SGRRRPTLDLLIPLARAHRVALDQLVTAPATGDPRVHLKPRSRERGSVLVPLTQYPGRV
                     QVFKQVLSHREPRLVTHSGYEWLYVLAGRLRLILGEREITLRPGEVAEFDTGEPHWFGP
                     ADAEAVEILHLFGPHGDQAVVRTGPAANG"
     gene            38207..39607
                     /locus_tag="ASD48_RS16135"
                     /old_locus_tag="ASD48_38095"
     CDS             38207..39607
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017237592.1"
                     /locus_tag="ASD48_RS16135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38095"
                     /product="MFS transporter"
                     /protein_id="WP_057602324.1"
                     /transl_table=11
                     /translation="MLTTSLAAPPSPLSARRRWTVLAVCALSMFLVGVDTTIVNVGLPE
                     IGHGLGVGTHGLEWVVNAYTVVLASLLIVSGALADRFGRRRVFQCGLLVFGLASLICAL
                     APSLGVLVAARAVQGIGASMLSPVALAIVVNAMPDPRERARAIGVWASVFGLSMAAGPV
                     TGGALIAAFGWRSVFWINAPVVVAALVLVAVFVPESRAERARRLDLPGQALLTVVLGLF
                     VGVLVEGPGIGWASPVALTGYALIAATTAGFVLVELRRAEPLMDLGLFRRPPFATAVLG
                     AMAVFAALNVSMLLNTLYLQHTRGWTPLASGAATLPMALGATLCAPWSGALVGRLGPRR
                     PLILAGTFTTAGGLCLTNLDQDTSVPLILLAHLLIGIGFGFANAPLTNTAVSGLPRSRA
                     GVAGAITSTARQVGAAVGIALAGGLVADAGPTGLAAASHPGWLLVAACGLLLFVVARAS
                     QPAAVQAR"
     gene            complement(39715..40365)
                     /gene="leuE"
                     /locus_tag="ASD48_RS16140"
                     /old_locus_tag="ASD48_38100"
     CDS             complement(39715..40365)
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="leuE"
                     /gene_functions="transport (smcogs) SMCOG1116:
                     Homoserine/threonine efflux protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009190286.1"
                     /locus_tag="ASD48_RS16140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_38100"
                     /product="leucine efflux protein LeuE"
                     /protein_id="WP_057602325.1"
                     /transl_table=11
                     /translation="MFGVVDLPTYLAGLVLIVLLPGPNSLYVLSVAARRGVRAGYTAAT
                     GVWCGDTVLMTLSAAGVASLLQANAVLFAIVRYAGAGYLTWLAVGMLRAAWRMWRTRRE
                     RVPAEDGPAEVSVERPFRRALVVSLFNPKAILFFVAFFVQFVDPGYAYPALSFVVLGVL
                     AQLASVLYLTALIFGGTRLAGAFRRRKRLTAGATSAAGVLFLGFAVKLSLAGA"
     misc_feature    complement(40378..40391)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.92"
                     /tool="antismash"
ORIGIN
        1 cctaccagga ggcgcgggcc gccctcgacc tggtgccgag cgggggcggg gtggcagcac
       61 tgccccggct gtccccgttc gactacctgg cgctgcgcgc cgacgacctc gcgcgccagc
      121 tggtcgatcc ccgggtgcgg tcgatgctgg aggaggaccg cagacgtggc gacacgctgg
      181 ccgccaccat acgggccttc gcggaggcgg acctcaacct gcggctggca gccgaccgct
      241 tgcaagtgca ccacaacacg gcgcactacc ggttgcgccg gatcgaggaa cgcaccggcc
      301 gcaatccacg ccggatcgcc gacctcctgg aactactggt cgccctcgcc atccgcgacg
      361 gggccgatga aggcggggaa tgcgagtgag cggcatggtg gagtctgccg gggccggggc
      421 aacacgtcag aggccgggcg ggcaggggag cgtgggcctg cctgaggaac aggccgggca
      481 ggacggaaac ctgcggcgca ctctgcttga cgccgcgctg ggggtgttca ccgagcgcgg
      541 ttacgccgac gccggtctca ccgagatcgc cacgcgctgc ggcatcccgg tgggcagcct
      601 ctttcagcac tacggcggaa agcgagggct gtacctcgcc ctgtgggagg agttccggga
      661 ggagcaggag cgtcggaccg cgaccacgct gaccgccgag cgcaaccgtg gtgtggacga
      721 ccccgtcgcc ctcttcgtgg cgggagccag ggcctacctg gagggtgcct gggaccaccg
      781 gaggctcggc agactcctcg tggaagacga tggccccgcg ggtttcgacg cgctgcggcg
      841 tcagtgggac cgcgcgtggg tgcggcgcaa tgcccggctc ctggagatcg acgagcggcg
      901 acgcgccggc cgggtccggg tgagcgtgct gaccaccgtc atcggagggg cggcgcgcga
      961 gctgggcgac tgcggggacg agacggaagc ccgggagatc gtggacgagg tgtgcggcat
     1021 cctgatccat ctgtcggcgg cgccgggctg acacgcccgg cacccctctg gtcccggcat
     1081 gcatccggtc ggccccgccc ggttgtcagc cccggctgtc gggggcgccc cgctgtcgcg
     1141 gcgcccggct gacacgcccg gcgtcgggct gggacgacat gatcggccac agcccgacga
     1201 cgcctcgctc cccggagacc ccgctccgcc tgctgcctca gggcgacagc gcccacctgg
     1261 tgtacacctc ggcatcgatt gcggcgtaat cccctctacg caccggcgcc ggcttcctgc
     1321 cggaacggca gcgggtcccc gaggagctgg ccgccgtcga tcaccatcgt ctcgccggtg
     1381 atccaactcg cggcgtccga gacgagaaag gcgaccgccg aggcgatgtc ggtcggctcc
     1441 ccgatacgcc cgagtgccgt cgcggcggac agggtctcct catggtcctt ccacagcgcc
     1501 tcggccagct tcgtgcgtac cacgcccggc gccaccgcgt tgacgcggac cttgggcgag
     1561 agttccaggg ccagttgctt cgtgaggtgg atcagtgcgc ccttcgacgc gttgtacaac
     1621 ccgatgttcg cctcgaaggt catgccgccg accgacgcgg tgttcacgac ggcgccgccg
     1681 tgctcgccca tccaggcccg ggtggccagc cctgtccaca ggaggggagc ccacaggttc
     1741 acgtcgaagg tcttggcgaa ccgggcgtgg tcctggtcga tgacgggccc gaaggccggg
     1801 ttggtccccg cgttgttgac gaggatgtcg aggctaccga agcgctcgcg cgtcagatcg
     1861 acacagcgcc gggccgcttc ttcgtcgacc gcatgcgcac cgacgccgat cgccgtgccg
     1921 ccgacctggg ccgcggcggc gtccgccgcc tcctgagacc gggaggtgag gacgacgttc
     1981 gcgccggcgg ctgcgatggc ctgggcgatc gccaacccga tgccgcggga ggcgcccgtg
     2041 acgacggcgg tgcgaccggt gagatccagc cccgccatgt cagttcaccc ccgcctcgtg
     2101 gccgccgggg gcattggtgc cgctcgccgc cgtggcggcc ccgtcgcggt accggcgcag
     2161 ttcgtgcctg gcgatggccc gcttgtgtac ctcgtcggga ccgtccgcca gccgcagcgt
     2221 ccgcagctgc gcgtacatca tcgccaacgg gaagtcctcg gtcactcccg ccgctccatg
     2281 cacctggatc gcacggtcga tgatcttcag cgcgatgttc ggggcggcca ccttgatggc
     2341 cgcgatctcg gtgcgcgctt ccttgttccc gaccgtgtcc atcagatacg cggccttgag
     2401 ggtgagcagc cggatcatct cgatgtcgat gcgcgcttcc gcgatccagt cctggatgtt
     2461 ggaccgttcg gcaaccgggc tgccgaaggt cagccgtgac tgcgcacgcc ggcacatcag
     2521 ctccagcgcc cgctcggccg cgccgatggc ccgcatgcag tggtggatgc gaccgggccc
     2581 gagccgggcc tggctgatcg cgaacccctc gccctcgccc ttgaggacgt ccttggccgg
     2641 cacccgtacg tcggtgaagt cgatttcggc gtgcccctca cggtcctggt agccgaacac
     2701 cggcaggccg cgcatcaccg tgatcccagg ggcgtcgatg gggacgacca tcatcgactg
     2761 ctgccgatgc ggagcagcgc tggggtccgt cttccccatg acgatgagca ccttgcagtt
     2821 gcggtgcagg gcgttggagg cgaaccactt gcggccgttg agcacgtacg cgtcgccgtc
     2881 gcgctccatc cgcaactcga tgttggtggc gtcggagctg gcgacacgcg gctcggtcat
     2941 cgcgaaggcc gaggccatcg tcccgtcgag caggggcttg aggtacttct ccttgtgctc
     3001 gtcactgccg aacagcgtga gcacctccat gttgccggtg tcgggagcgt tgcagttaca
     3061 cgcttcgggg gcgatgtgac tgcgccccat gatctccgcc agcggcgcgt actcgaggtt
     3121 cgtcagcccg gggccccact ccgggtgggg gtgaaacagg ttccacagtc cgcgcttgcg
     3181 cgcttccgcc ttgagttcct cgatgatcgg cgggtggaag tgcgggtcgc ccgacgcgcg
     3241 catctgctcg tggtacacgg cctctgcggg gtagacatgt gcatccatga attcgagcag
     3301 gtccgcctgg tacttcttgg cgcgatcccg catctcgaac agggacatcc gaactcctga
     3361 cggttaggaa gggaacgttg cgccgacggc gcttcccgga cggtcggcgt ggactctgct
     3421 tcagaccgtg ccctcgccga actgtataat tgaatctggc gtcaggttca agagtgagcc
     3481 acacggcacc gcacgaggaa cgcagcgcgg cccccacgcg gaggcgacgg cccaggagga
     3541 gacgagaaaa aagaaacacc cgacggtgcc gggtgtgatg aggcaggcgg tccgggctgc
     3601 cgggtcagca gtggccgggg aacctcaggg cgttcgccca gagccgggtg accgtggaca
     3661 cgagctcctc gaagtccacc ggggcgcctt cttcttgccg ttcgcccagc acgaaggcgt
     3721 tgtaggccat gacgctgacc atgcccgaca gggcgcggga ggccatcatc ggatcgacct
     3781 cctggtcggc gacgccccgc gcctgcaggt cggcgatccc gcgggcgttg cggcggatga
     3841 acgcgtcacc gcgccggctg cggaactcac ggaattccgg ctccacttgc gctacctgct
     3901 caagcagggc catcagcttc gcgttccgct tgtacgcctc gaggtacgcg cggttgctcg
     3961 cctcgaggac cgcgaaggga tcatcggtat cctgcacccg gcccatgccg gggtgcagca
     4021 tgtcctcctg cgcctccagg aggacggcgg cgagcacctc ctccttgttg gcgaagtagg
     4081 tgtagaagga tcccgccgcg catcgcgctt ctttggtgat gtccgtcagg cgagtgtcga
     4141 ggtagccgtc ccgctcgaac accttccgcg cggccgtcac cagggcggcc cgcgtccgcg
     4201 ctccgcgctt cgtcgcgggc ggctcgcgaa ggggggcgag gggcgccatg ggaggcacct
     4261 tctcgccgtc gatctccccg gccgctctgc tgtccatccg cgagacccta cttgaatccg
     4321 acgccacagt cacaacctgc gaggcggtgg gcgacgcctt ccggggaggc gggcggtcag
     4381 gcggtgatcc cgaaacgttc ggcgagtcgg cggcgggtgt cggcggcgct ggtgtgcagt
     4441 acgcccccga ttccgatccg tgccgccccg tcgaggttct gctgcagatc gtcgatcatg
     4501 accgcctccc cgggatcgac gcccaggcgt tcacatgcga tcgcgtagat ccgccgggag
     4561 ggcttgcgga tccctacctc ggcggagatg acgaccgcat cggcgacggc ggcgaggtcg
     4621 acgccgtcgt aggttccggt gccgaacgca ttggacacca gcgcaacggg tcggccggcg
     4681 gctcgaagat caccgagcag ggcgagcatg tcctgatcga tcgacatgcc cgcctgcatc
     4741 cgggccgtga gcccctcggc ctgtacgtcc gcgccgtgga cgcggagccg ttcggcgaat
     4801 cctcgctcga agtcctcggc gccgatacgg ccgcactcgt ggtcggccag aagggcgcgt
     4861 gatggctggt cccggccgag gaggtccagc ggcagacgcg ggtcgccgcc gagcgaggcg
     4921 ccgaagtcag tgaaagcctg cagcacactg gaggtgatga cccctccgaa gtccaccagg
     4981 accgcggttc gggccctgtc cacttccctc gacacgatat ccacgcctct ctcacggtcg
     5041 gcccgctgcc gcgcgatgcg acggcagcca cgttgtccag cagggagcgg gacctcagac
     5101 gacctcgaac agtccggccg cacccatgcc gccgccgacg cacatcgaga tcaccacgta
     5161 gcggacgcct cggcgcttcc cctcgacgag ggcatgtccc accagccggg cgccggtcat
     5221 tccgtacgga tgtccgaccg agatggcccc gccgtcgacg ttgaaccgct ccggatcgat
     5281 gtgcagttcg tcccggcagt acaacgcctg ggaggcgaag gcctcgttga gctcccacag
     5341 gccgatatcg tcgatggtga ggtcgtgctg cttcagcagt ttcggaatgg cgaacaccgg
     5401 accgatgccc atctcgtccg gcccgcatcc ggcaacggcc ataccccggt agacacccag
     5461 cggttccagt ccgcggcgct cggcctccct cgcctccatc agcaccgacg ccgaagcccc
     5521 gtccgacaac tgcgaggagt tgcccgccgt cacgctggaa cgcgcgctca cctgaccgtc
     5581 gggcagcacc ggcgccagcc cggccaggcc gtcgagagtc gtcgacgcac ggttgccctc
     5641 gtcccgggcc agggtgacct cctcgtcccg caactccccg gactccttgt cgagaacctt
     5701 cttggtgctg gtgagcgcga cgatctcccg gtcgaaccgg ccggcctcct gcgccgccgc
     5761 ggtgcgctgc tgtgacacca gcgcgaactc gtcctgccgt tcccggctca cgccgtagcg
     5821 ttcggcgacg atctctgccg tctgcaacat cggcatgtag atgcccggct ggtgctcgac
     5881 cagccaggga tccgccatgc gatgggtgtt catgtggtcg ttctgcacca gggagatcga
     5941 ctcgacaccg ccgccgacag cgacctgcat gccgtccgtg acgatctgct tcgcggccgt
     6001 cgcgatggcc atcaggcccg acgagcactg ccggtcgatc gtcatccccg acacgaggtc
     6061 cggcagcccg gcacgcagag cggcctgacg cgcgacgttg aaacccgagg acccctgctg
     6121 cacggcacag ccgaagacca cgtcctcgac ctcgcctccc tcgagcccgg cgcgctgcac
     6181 cgcgtgcgac agggcgtggg cggcaagctc ctgcgcctgg gtgtcgttga acgcgccgcg
     6241 gtaagccttg ccgatcggcg tccgcgccgt cgaaacgatg actgcttccc tcatgtcgcc
     6301 tcactgtttc ctgttgaccc ggttggtccg ggagtctcgg ggccgggatt ccgagcgccg
     6361 cgagccgggc tcgatggccg acagcgggcg ccgaacgcca actgtggcgt ggagagggct
     6421 cgtgaccgcc tcctcgatcg agcgatgacg tgcgtccgca gcggtgacag ggagtcgacc
     6481 ttccgatcgt tatagttgaa ttcggcgtca tgttcaaccg cgggcaggcc ttgacagtcg
     6541 aactaccacc tgaagggtac cgacccgtcg gtatgaaggg gggagcgtga cccagctgag
     6601 cctctccacg ggtgggcgtg tgcgacgcgg tcacggcggg tccgccccaa gaccgcccgg
     6661 tgctgctgca cggcttcccg cagacggggc tggtgcggca acgccaggtc gccgccatgg
     6721 ccgcgcacgg ccaccggtgg tggcgcctga ccagcgtgac cactcccccg gcgcccgccc
     6781 ccagcggccc gaggactatc gcatcagcct tctcgtcgac gacgcggtcg cggtcaccga
     6841 agaacggggc ttggccacgt tcggcctggt cggccatggc tggggaggcg cggtggcctg
     6901 gtggaccgct cacacctacc ccggccgcgt cgcaccctga cggctgtctc gcccccgcgc
     6961 cccggacgct ccggccacca ccccgcgcac caaccaggat cagcgcgaac gctcgcacga
     7021 catcgactgg cgcgaatcac ccgcggccga agagcgcatg ctcgcccacg aggcccaagt
     7081 gcttcgcgat ctggaggaag cgcgttccgc ccggccaccg cacaggagac cgggcggcgg
     7141 ggtcaacggg ccgtaccggc ttctggagac gcctggcgcg ctgggcggca cttgggactt
     7201 gttccgctac gcgggccgcc cgggcttcgc atgaggcgtg ggttacatac cggccgcgag
     7261 atgaagacaa agccgcgcgg cctacgtatt gcctcccgga gaagaagcgg gggaaccgcc
     7321 ggcgtggcgc cctgcgcaga ggccctcgca gtgatcagta cccggcgcct ggtccctgac
     7381 cgccgctgac gaaagaaacg gcccgtcaga acaagagaag ctgaggagga cacgtggatc
     7441 gcaacgacgc cagtcctgag cggactcccg cctcagaccc tgacatcgcg catgagctca
     7501 gggactcctt ccgagccgtg ctggacgctt tggacgccgc acgcgccgac ctcctgcgcg
     7561 aacagcagca ggaacgcgcc gagggcgcgt ctcgacccca gagccggccg cgtccgccga
     7621 ccggggatgc ccgctcgccc cagccggctc cgacgtcgcc ctcgtcctcg accccggctt
     7681 cctccgcgtc ccgccgggca ctgccggtca gacgtgtgcc gtcaggcgcg cggcctgagc
     7741 gtcccgggcc ccaccggccg actgccgccg aacggccgtc ggccgccggc ccgcgccagg
     7801 ccggcacccc ccaccctgtc gtggcggaga caccggggtt gcccagaggg ctggaggccg
     7861 tccctccgcc gccggtgggg aggccgccct cggccagtgg accgggcccg caggttgtcg
     7921 caccgccctt ggcttttccc actccggctc cctggcagga gagcgggcgg agcagaagcc
     7981 cccgttcggg caccgattgg tcggacgtcc ccgaccatcc ggctgtcccg ctcgccaccc
     8041 caccctccgg gggatatccg ccatctgtcg gcccgcgcgg acgcacgacc agtggcagac
     8101 ggcggcgagc caccagctcc aggaacctgc gcgtcatcgg aatctacggg ctgggcgcgg
     8161 ccagcggatt gctcctcgcc tctttgctgc tgatcgacca caacgccgag acttcgcgct
     8221 ccgcttcgtc tcccgggcac atggaaaccc cactgccgct gactcccgcg ccggaggacc
     8281 cctcgccccg ggctccaggg cggccggacc cctcgcagcc cggcacaccg gacccgcggc
     8341 tccccgaaat tccgggcacg ggcgtcctac gccagggcga cagcggccat ggggtctatg
     8401 agttgcaggt tcgtctcctg cagataccgg acatctatag cgggggcccg atcgacggcc
     8461 gctacgacac gaggctccga gcggcggtga ctctgtttca ggagcagtac gggatccgcg
     8521 gcgatgagag cggggtctac ggcgacaaca cgcgtttcgc cctcatgctg cggaccaaat
     8581 agccggcggc ggaaggtagg ggccccggga tcccgccacc cggctgcgaa gccgagcagg
     8641 cgccgcacgc cacgggctgc gtgccggagc ggcccgtcac gtcaggctcg acgggacgat
     8701 cccgtagcga cgcatcttgc ggtacatcgt ggcgcgggag atcccgaggt cctgcgcggt
     8761 gcgctggacg ttggagtcgc ggttcaccaa cccacgcatg atggcatcac gttccagcgc
     8821 ctcgatggtg gtgaggacct tgttcgacga cacccggcat tccggcggca agtcctccac
     8881 atggatcatc cggcccgaag gccgccgcgc caggccccgg atcaccgact ccagctgccg
     8941 gacgttctcc ggccaggggc atcgctgcag cacggtcagc gcatccgggg agagtctgct
     9001 ctcgccgctc ggccggtatt tgcgcaggaa gaaccgcgcc aggtgctcgg tgtccccata
     9061 gcgatgacgc aggggaggca cctccaccga ggcgccacag cgctgatcga gctggtcgtc
     9121 ggcgccgacc agcgacggct ggccggtcac gaccagttgc ccgggcgcgc tgccgtccag
     9181 ccgcaccagc aggttcgcca gccgctgccg cagccggtcg ccgagcaggt ggacgtcgct
     9241 caggacgagc acgttggacg gcacgccaag cagctctccg atgtcgtgca gccagcgctc
     9301 ggtgacggcc ggtgcatccg acagcggcgc ttgcgtcagc tccagccgac gtccggcgcc
     9361 gtgggcccgg tgcagggcct cgaccagcgt cctcttgccg acgccggctt cgcccaggag
     9421 attgagccat gtcccggcga cgaacgctgt ttcgctgtcg gcgaccgccc gcagccattg
     9481 cggggacgag cccaccagtc ccaggtcggg gcgggcgggc gcggcggaaa ccgcatgtgt
     9541 gggctgggac cgtccgatca gccggactcg caagacggcg cccgcgtcac ggtcttcgcg
     9601 ccggcagcga ctgaccctga gttcggcgac ccgtcccgac ggcagggcga tgctacgggt
     9661 cccctccagc cggggatggt cggcgatctc acgggcgtgg tcgagcagcg catggtgatc
     9721 cggcccggcc acggcggcac tgagctgctc gttcatcatg acgacatcac ggttgagggc
     9781 cagcacgggt cccggtcgcg ccgaggagca cgcctccatg tagtcgtgga aaagagcccg
     9841 ctcgcgccgc gaggtgatcg ccgcgatttc ggcctcgatc tgagccgcga ccgagcgtgc
     9901 gaaggccatc agcatgccgt cggagccctg acggatggtg gtgaggttga aggctcccag
     9961 cagggtgcgc cgggtgggat gcaggatcgg tacggccgca cagcggaagt cccgcagcgc
    10021 ctcgacgtag tgctccgttc cggcgatcat gaccgggcgg ccgctggcca gcgcggtccc
    10081 gatgccgttg gtgcccacgt aacgctcggc gaacacatgg cccggtgcca ggtgtacgcg
    10141 gttgaggttc gtcgtcagcc cctcgtggga gacctttcgg gagaggacca cgccgttgcg
    10201 gtctgtgacc atcgtggaga cggggtcgtc ggcgagttgc tcgtgcagcc tgtccaggat
    10261 cggcagcgcc gccctggcga ggtggctgtc cagattgggg ttgtccaggt acggagcgtc
    10321 gaggctgccc ggcatcacct cgtattccat cgagcgatgc catgaggcca ccacgagcgg
    10381 ccgggcgctt ggatccttgg tgacttccag gtagagctct ttggctgctc tcagtgagcg
    10441 tccgggttgt tggcggggca ttaacactcc cgtactgcgc gcgtcacaat ccctcggtgc
    10501 agtgattgga ccagttcgac ggtgtgacac ctacggcgtg tatcacattg agacattcgc
    10561 ggacggattc tgagacatcg acctgcgagc ggcggcctgt gtaatcggcg caccacccac
    10621 ccgccgactc gcagggagcc gccatgaaag ccgtgcaggt catcgagtac gacgagccgc
    10681 ccgtgctcgt ggacgtgccg gacccgcaga tcaccggtcc gctggatgtg atcgtgaaga
    10741 tcgggggcgc cggagtctgc cggaccgatc tgcacatcct cgaaggccag tggaaggaga
    10801 agagcggggt cgcccttccc tacacgatcg gtcacgagaa cgccggctgg gtcgctgagg
    10861 tcgggcaggc tgtcaccaat gtcaaggtcg gtgacccggt catcctgcac ccgctggtga
    10921 cctgcggtct gtgccgcgcc tgccgggacg gcgacgatgt gcactgcatg aactcggcct
    10981 tccccggcat cgacgccgac ggaggctacg ccgagtacct caagaccagc gcccgctctg
    11041 tcgtgcccct cgccccgtcc ctggagccgg cttcggtggc ggccctggcc gacgccgggc
    11101 tcacggcgta ccacgccgtc gccaaggcgg cccgggtgct gcggcccggg gacaaggccg
    11161 tggtcatcgg cgccggcgga ctcggacata tcggcattca ggtgctgcgg gccctgtcgc
    11221 cggtggagat gatcgtcatc gatcgcagcc cggaggccct ggccctggcc gaggtactgg
    11281 gtgcagacca caccctcgtc gcggacggaa gcgaaaccga ccgcgtacgg gacctcaccg
    11341 gcggtcacgg ggcggaggcc gtcctggact tcgtcggcga ggggggcgct gtcgagacgg
    11401 gcgtggcctg cctacgccgc aacggcaact actacgtcat cggctacggc ggccacctcc
    11461 acgtgccgac gatcgacgtc atctccacgg agatcaactt catcggcaac ctcgtggggt
    11521 cctacaacga cctctccgag ctgatggtcc tggcggcccg ggacaaggtc accctgcaca
    11581 cccagcgata ccccctcgcc tccttccggc aggccctcga cgacctggac accggggccg
    11641 tacgcggccg agcgatcttg atcccctgac accgcaggag aagccccatg cgcagcagac
    11701 cgtacaaggc cctggtcgcc gtcgccgccg tcgcggccct gaccgccacc gcgtgcaccg
    11761 cccaggacga ggcacagcaa aagcccaagg agaagaccgg gctcttcaag cccggttcgg
    11821 agatcagcta ccagaagtac ggcaaggact accccgatac gaaggtcagg gacgtccccg
    11881 gaccctgcag ctacgactcg atcagccgca aggactactc cggacagaca ctgaagatca
    11941 tcagccacgc cgttcccgtc atcggcgagc cgacccagct gcacgcgaag cagttcgagg
    12001 acatcaccgg cgggaaggtc caggtggtca acgtcccctt cggcgagctc catcagaaga
    12061 tcctcacacc cctccaggcg ggccagccgg cgtacgacgt catgttctac ccgtccctgt
    12121 ggatcggcga catggccccg tatctggccc cggtaccgaa gacgtacctg gacagccccg
    12181 gcatgaagga cgtcaccacg gcctacatgg acgtggcgac ctggaacggc aaggtcgtgc
    12241 agtacccggt ggacggtgac cgccactacc tcaaggtccg caccgatgta ctgaaggacc
    12301 ccgagcggca ggcggagtac aagaaggcca cgggtaagga actgcaggtc ccgaggacgt
    12361 gggccgagta ccaggagatc gccgagttct tcagcggcaa ggacctcgac ggcgacgaca
    12421 aggccaacta cggcagtgcc gaggtgacca agcgcgacga cctgaccttc tccgcgttca
    12481 tcagccgtgc ggcaccgtac gtgaagaacc ctgacgtcaa gggcggcgtc ttcttcgacc
    12541 tcaagaccat gaagccgctg atcaacacgc cgggcttcgt ccgcgcgctg gacgacatgg
    12601 tgagcgccag gtcgacctgg gcgcccggcg gcgccaactt cggcctggga gacgagatct
    12661 tctccttcgg aggcggccag acgctgatgt cctactcatg ggacgacgcc ttcatccagg
    12721 cccagcagtc ggacagcagg atccgcaaca aggtccaggc ggcgccgctg ccgggctcca
    12781 cggaggtcta caaccgcacg acgaagtcgt gggacaagaa gacgaaccag gctccgtact
    12841 tcacctgggg atggacctca gcggtggccg aggcctcgcg ccaccagcag atggccttcg
    12901 actacctctg cttcttcagc aacgaggcca acaccgccct cgacctgacc atcggccgat
    12961 tcggtgtcaa cccctaccgc tatgcccact tcgacgcgga gttctgggag aagcagggct
    13021 gggacaagga cgtcgccgag tcgtacgtgc gcacgctcgc cggcatggag aagagcacca
    13081 accgcgtctt cgacctgcgc gttcccggtg tcaaccagta catgtccgcg ctggccaacg
    13141 gtgtcgccgc ggctctggcg ggacagagct ccccgcagca ggcactggac gacgtggccg
    13201 aggaatggtc gaagatcacc gatcagatcg gcaaggacaa ggtccaaagc gcctatcgca
    13261 acgtggtcgc gctcgaggac tactcctgat ccgaccgcag gacgccccgg gtggccggac
    13321 cggaccggcc ggtcacccgg gggcgcccgc ccccttccgc aaggagaacc atggacggcc
    13381 tgcgccggca caagagcatg ttcctgctgc cgggactgct cacgctcttt ctgatcatca
    13441 ttttcccgct tctgttcacc atccgcgtca gcttctccgg ctggaacgtc agcaatcctg
    13501 cgatggactt catcggaggc gccaactaca cggcgatgct gcacgacagc cgcttctggg
    13561 cctccgtcaa ccggctgatc ctgctggcgg gcggcacggt cctgatccag tacgtcatcg
    13621 gtttcggtat ggcactgctg gtctggcgcg aggcacgcgg ccgcagattc tggcgggtgc
    13681 tctttctcgt ccccatgatg accacgcccg tggtcatggc cgccatctgg cagacgatct
    13741 tccatgagtc actgggaccg gcgaacgacc tgctggggat gctgaacctg ccgagaatcc
    13801 cctggctcac cgagtccggt ccggcgctgg tcgcgctgat gaccgtcgag gtctggcagt
    13861 ggaccccctt catgttcctg ttgctcctgg ccggcctgct cagccttccc aaggaaccgt
    13921 tcatggccgc cgcgatcgac ggcgccggca cctggcgcac cttctggaag gtgaccttcc
    13981 cgctgatggc gcccgtctcg gtcgcggcgg tcatcatccg gctggtcgag gcgtccaagc
    14041 tgtccgacag cgtctacgtg ctgacgtccg gcgggccggg gtcctccacg gagaccccgg
    14101 gttactacct ctacatccag gggctgcgcg atcagcagac cggctacggc ggggcgatgt
    14161 ccctgaccta cctcgtcctg atgatcgtca cgctcacggt cgtcgccgcc ctgctcacca
    14221 gggccttcaa gctgaagggg gactcatgag gtcacgcctc taccccgttt tcaagtacac
    14281 cgtgatcgcc ttgtgggcct gcttcgtcgc gggaccgttc ttctgggcga tgacgaccag
    14341 cttcaagaac gccaacgccg tccagggcgg tcccacctac cttccctggg tgcagtacaa
    14401 gcccactctc accggctggc gcaacatctt cggcggagcc ggcggcatcg atgtgatcga
    14461 tcccttcatc aacagcgcga tcatcaccgt cgccgcgtcc gccatcagcc tggccctggg
    14521 atccctggcc gcctacgcgc tttcccggta ccggttcagg ctgggcttca tcaagaacag
    14581 cgacatcgtc ttcttcttcg tctcccaacg gatcatgccg cccgtcgtcc tggtgatccc
    14641 cttcttctac ctcctgcagt ggggtggcct cctggacagc atcccgggcc tggtcatcgt
    14701 gacggtcgca ctgctgctgc cgatcgcggt ctgggtgatg gtggacttct tcaacggcat
    14761 cccccgggag atcgacgaga tggcgatgct ggacggctgt cccccgttcc agaccttcgt
    14821 acgggcgatc ctgccgaact ccctgcccgg gctgaccgtg gcggcgatgt tctgcgccgt
    14881 gttcggctgg aacgacttct tcttcgcctt ccggctgacc ttcaccgagg tccagaccct
    14941 gccccaggcg gtcgtcgccc tcaactcctc cattccaccg tggtggacgc tgtccgccgc
    15001 cgcgctcttc ggcgtggcac cgctgatcct gctcgccctc tgggtggagc gcctactgtc
    15061 caaggggaac ctgtcgggag cggtccgatg aatttcagcg ccactgatct gtgtctgacc
    15121 gtcgacggcg tcgaccacct caagaacgtg accgccacct tccagccggg acggctccac
    15181 accgtcatcg gccggacgat ggccgggaag acgacgcttc tgcgggccct ggccggcctg
    15241 cagaaggtgg actccggctc gctgacccgg gcgggagccg acttcctgag gacgccggtg
    15301 tggcggcgcg acaccgccat ggtctaccag cagttcatca actacccgca tctcaacgtg
    15361 ttcgacaacg tggccttccc gttgaagcgg gccgggctgt cacggaacga ggtccagcga
    15421 cgggtccggc agagcctggc gagcgtgggg cttgcggact tcgagaagcg caaaccctcc
    15481 caactctcgg gcgggcagca gcagcgcgtc gcgatggctc gcgccctggc ccgcggtacc
    15541 ggcatcctcc tgctcgacga accgttggcg aacctggact acaagttgcg cgaacagctg
    15601 cgcgacgagt tcaaggccct cttctcggac cagggcgaca cgatcgtcat ctacacgacc
    15661 accgaacccg ccgaggccat gatgctcggg gacgtggtcc tggtcatgca cgaggggcgg
    15721 atcctccaga ccggcacacc gcaggaggtc ttcgaacatc cggcgaccac cgcggtggcg
    15781 tccatcatca acgatccgcc catgaacatc ttcgcgggcc ggaccgaggg aggccaggtc
    15841 atggtgaccg gcttccaggc cacgcacgtc tccgcgcacc tggccgacct gcccgacggt
    15901 gcctaccagt tcggcctgcg cgccaccgac gtcagcctgg cttccggtgg ggtcgaggcc
    15961 gaggtcacct tcgtcgagat ctccggctcc gagaccttcg tccatgtggt cgtcggcgag
    16021 acccccttcg tcgtacggat cgagggcatc cacgacgtcg ccctcggtga cctggtcaga
    16081 cttcgactcc gtcccgaccg gctgttcgcc ttcgacgagc aggggacgct cgtgcgaaca
    16141 ccttcgtacg atctcgcttc agtggaaggg cgctgatatg gcgcagttgg acatcgtcga
    16201 cgtcgggcac gcgtacacgc cgggtgccga ggaggagcag tgggctctca agccgctgaa
    16261 actgaccttc gagtccggca agacctatgc gctggtcgga ccctcgggct gcggcaagac
    16321 gacgctgctg aacatcctgt ccggcctggt cagaccatcc cggggacagg tgctgttcga
    16381 cggcctcgac gtcaccgccc tgcccaccaa ggcgcgcaac atcgcccagg tcttccagtt
    16441 ccccgtcatc tacaagtcga tgacggtcta cgagaacctc gccttcccgc tgcagtgccg
    16501 gcgttgggac aaggcgagga tcgccgccaa ggtgcagcag gtcgccgagg ccctggacct
    16561 gcacgatcgg ctgcgccaac ccgcccgcgg cctcaccgcc gacgacaagc agctgatctc
    16621 gctcggccgc ggcctggtcc gtgacgacgt ggcggccgtc ctgatggacg agccgctgac
    16681 cgtcatcgac ccgcagctga agcactcgct gcggcgcaag atccgtgaga tcaccgaaca
    16741 gttccagccc acggtgatct acgtgaccca cgaccagtac gaggcgatga gcttcgcgca
    16801 ggaattgctg gtcatgaagg atggccgcgc cgtgcagcag ggcaccccgg agcagctctt
    16861 cgaggcgccc tcctccacct acgtcggcta cttcatcggc tcaccggcga tgaacttcct
    16921 tgccctcgac cgtaacgacg ggcccttcga gctgggcggc cggacgctgt ccgtcgcctg
    16981 ggacatcccc cacagcacga ccgacgtcca ggtcggcgtc cggcccgaat acgtcagggt
    17041 cgtcacgacc cccggcctca acaccttccc cggccgactg cggggggtca gcgaccacgg
    17101 cgcacagcgc gtgctcgagg tggaggtcgc cgggcaactc gtcagggcca agacgccgcg
    17161 ggaggaggga gttccggtcg gcgaggaggt tctcgtgcac ctgccgcgcg ccaaggtcct
    17221 tccgtacgtg gacggtcggt tggcactccg gtcgtgacga ccgtcgggca tgcccgcgcc
    17281 cctgcccgcc cgaccacagc gcgttggggg ccgcgggccg tgcgacggaa cgccgcgaca
    17341 ctcaggtgtc cgggggtccg taatccggcg acggcaagcc gcagcggtta cgcgaaggtg
    17401 acaagccgcc gaccgtcaca caccggcagt gaccgagcgt cggagcgcac tcacctacca
    17461 gcgatccgta gcccgagcag ctgggctgga cgggacccgt cttcgcccgc cccgacttcc
    17521 cgcccgcatg aaccacgggg caccacacaa cggtggtcga cgagtaccgg cgggcggcgc
    17581 ccgctcccct ctcggcgtca tgagcacggc cccgcccgtc gcggcatggc tcacggccgg
    17641 cggtgaccgt gcgatccgct ggtgggcgaa gcgacctccg gtgttattca atgaggtgtg
    17701 cggtcaggga tctcggggcc cggtcgcacg ggtccgagta cagccccggc gctgtgccgg
    17761 ggattgccga gagagccgca tggactccac gccgtcgccc tcgtcctcat cgccgttcga
    17821 cctggtcagc agtgccctgg ggcgctacgg ttcgcgcggc ggagcggcag cggccgccgg
    17881 tcctgacaac gcggcgggcg agcacaccac cggccgacgc gcagccgaca gcccggcggc
    17941 cgaccggcac gaccagattc tcggcgtggt gaacctggac cgggatctga ggatcacccg
    18001 ctgcaacctg gacgccgccg tgttcgcggg tctggacgcc gcgcccggga gcctcttcgc
    18061 cgatctcctg ccccccgggg acgtaccgac ggtcacacgg cgattgcggc aggtcctgga
    18121 gatcggtgag gcgcacgtcg cccggatcca gcgcctgcgg cgctccgacg ggtcggagct
    18181 ggtggtctcg ctgagcatcc tgcccgccgc tgcgcctcag gagggtctga ccgtctccct
    18241 gatcgccatg gccaggaggc tgcacctgta cgccgccgag accgcgatcg gcacctcact
    18301 ggacatcggc gagaccgccc agtcactggc ggagtcgctg ctggcctggg gagacgtggc
    18361 cgccgtcgac ctcgacttcg ccgtgtggac gggcgagggt gtcaccgatc aggcgcaggg
    18421 ccgcatccgg ctgcggcggg cagccctggt accggaccgg gcgtggcccg agggttacgt
    18481 gaccccgggc ggcgatcttc cgagtgacgc cagtcgcctg ctggcacagg cggtactgcg
    18541 ggacgacgcc ccgcaggcca tcgtcatacc cgaccgcaag gcggtcgagc ggctgctcgg
    18601 cagtccgcgc gtgatccgcg cgctggtacc cggtgaccgg tcggcgggtg tggcgtgcat
    18661 gccactggtc ctggacagcg tgccacccgt cgtactgggt gtcgcggagg tctggcgacg
    18721 ggcggaccgc cccttccgcg acggcgagct gttcgacctc caggaactgg tggccaggac
    18781 cgcccatcac gtcgacctgg cccgtcagca ccagcgcgag cacacgcagg tgctggcgtt
    18841 gcagcgccgg ctgctgcccc gcacgggcgg ccacaccctg gagatcgcca gcatctacca
    18901 gcccgccacc cccgacagcg cgggcgtcgg cggcgactgg gtgaacagtt ttcccctgcc
    18961 ggacggccgt accgcgctgg tggtcggcga cgtcgtcggg cacggcctgg gagccgcggc
    19021 gaccatgggc cagctgagca tggaggcccg cgcgctgctg tccgcggggc tggcaccgga
    19081 cgaggtgctc gaacatctgg acgataccgt gacgctgctg gacgacgcgg agtccgggct
    19141 gacggccggc tacagcgccc tcggctccac ctgctgcatc gccctctacg acccggtcgg
    19201 ccaccatgtg acgctcgcca gcgccggtca cctcccgccg gtcctcgtcc ttcccgacgg
    19261 tcgcgcggcc ccgctcgcgg tccgccccca tcccggcctg ggcgtcgagt tcgcgctgcg
    19321 ggagccgttc gacgtgcaca cgttcgacgc gcctccgggt tccctgctcg ccctctacac
    19381 cgacggcctg gtggaggacc cggccctgtc gatcgacgag ggcatcgcca ggctggcgga
    19441 caccgtggcc acggtgcatc cctgggacac cctccagcag gccgcccggc atgtggtgtc
    19501 cacgctggcg ccggtgcgtc agcgcgacga cgtgaccctg ctgctcgcgc gcatgatcgg
    19561 ctaccgcaag gaggacaccg cgacctggcg gctgcccgcc cgtgcggacg cgcccgcccg
    19621 tgcccgcgcg cacgtctccg cgctgctgcg gcggtgggac agcaggagcg acacccggga
    19681 cgacgtgacg ctgctggtca gcgaactggt cacgaacgcg gtgcgcttcg ccgccggccc
    19741 cgtcacggta cggctgatca gggcgggtca cgtcctgctg tgcgaggtgg gcgacaccgg
    19801 caacggcaga ccgcggctgg gccggggcga cctcctcgac gacgccgggc gcgggctgca
    19861 catcgtgcac aggctcacca cccggtgggg tgtgcggtgg acggacaccg gcaaggtggt
    19921 gtgggcggag gtcgccggat gacgcagccg cggatgggcg cggcccggat gcgctcgcgc
    19981 gagcgcggcg cgacctcgcg ctacagccat tccccctcca gggcggtggc ggtgaggccc
    20041 ggtgccgccg cgtacaggac ggcgcggctg cccggcttct gcccggcgtc gtgcgcccgc
    20101 ctcaggatgt cgaacacggc ggcgccgccg cggttgccgc tggtgtagct gtcccggctg
    20161 tagtccagca gccccgacgg ccacgcgtcg ggcatcgtct gctccatgta ctccagcacc
    20221 cgggtcccgc cggggtgcgc cagcagcaca tcggggtgcc aggcgtcggg gtcgtcctgg
    20281 taacgcaggc gcagccactc ccacatcgcg gtgaccgtct cctggacggc gcgcggcccg
    20341 cgccggtcca tcacgaagtg ggtgccgtcc gcccgcgtct ccagacggtg caggtcctgg
    20401 gtgccgggca gggtgtggtt ccaggaggcg tccagccgca gcaccgactc gctcctcggg
    20461 cggcccgtga ccaccgcggc gacggcggtg tccgcgaaca gcaaccggac gatgagcgac
    20521 tcgatggtgt cgtcggcggg ctggtaggtc gtgctcagcg cctccgcgat cacgaccagg
    20581 accacccggt cggggtccgc ggccacgaga tcggccgcca gggccaggga gcgggtcccc
    20641 gcgatacagg cccactgcgt ggccggcagc aacatcacgt cgtcgcggag cgcgagcttg
    20701 tcggccaggg cgatgtccag acccggcagc gccggggtgg tggagtgact ggtgatcagg
    20761 cagtcgacgt ccgaggcgtc cagcccggcg atctgcaggg caccgcgcgc cgcacgctcc
    20821 ccgtaggact gcacggcctc ccaggccggc gcggtgcgct cctggacggt ctgcggcgcg
    20881 ggtatcgctt cgagggcggc gatcacgcgg cccacgtcct gtccgctgaa cccttcgcgc
    20941 gccagcgcct cttgagcggg tccgttgccg acatcacgca ggccgctgcc cttcccgggc
    21001 gcgacggcgg tctccagcgg cagcatccac ccgcgggtct cgatgcccgt actggccgcg
    21061 atgccgtcga tccgcggtgc ccacgccgcg tgcggatgcc ggtcgcgcac ctccgccacg
    21121 atctggctgg tctccacggc gtgctcgccg tgtatcacgg cagggggaca gaggtatgcg
    21181 gccatgatgg gcacctttcc gaggaaacga ggaggaacgt cacgaaggct gcgccatggg
    21241 ccactttgga acctcgcgcc catgccggcg ggctcccgtc cgggagtcgc tgtcgccatc
    21301 gagcatggac gccaaatgga catttccgct gtgactcaga caacttggac ggcttcttgt
    21361 ggcgtgatac ggcacacacc cccatgccgg tcccccaccg tcccgcctac gtgacgctca
    21421 actgtcggac cgtcaacttc cctttcggcg ggctggcggc cctcacctcc ggccccggca
    21481 gaccattgga tgcgccctgt tcaccgtggt cttcctcgtt cgggccatcg gcaacggcac
    21541 cctccggcat cggcgcctcc gcgccatgca agcgtccctc gacggcgaga gcgtcccagc
    21601 tcgcgctccc cccaccgcac acccgaaggg ggacgacgcc tgacaccgcc tgacactccc
    21661 tgacaagcgt cggcgaccgc cgtcagcgcg ctgtccgcgg actgtcagcg actcccggca
    21721 tcgtcatggt catcgagaac gacgaggatc tgacgaggag ttgttgaaca tgacgtacgc
    21781 gatccgggcc gaggggctgg tcaagaagta cggcgatttc accgccctgg acggcgtcga
    21841 cctggaggtc ccggccggca aggtcgtcgg cgtcctgggc cccaacggcg ccggcaagac
    21901 caccaccgtg cgcatcctgg ccacgctgat gcgccccgac ggcggacacg ccaccgtcgg
    21961 cggccacgac atcgtcaagg acccggtcaa ggtccggcag ctgatcgggt tgaccggtca
    22021 gtacgcctcc gtggacgaga gcctgtccgg cgccgagaac ctggtgctca tcggccggct
    22081 gctcggcctg tcccggcgcg atgcgaaggc gagggccgcc acgctcctgg aggacttctc
    22141 cctcgccgag gcggcccgca agccgatcgc caccttctcc ggcgggatgc gacgccgtct
    22201 ggacctggcc gcctccctgg tgggccggcc ccaggtgctc tacctggacg agcccaccac
    22261 cggtctggac ccgcacgccc ggcaggaagt ctgggaggtc gtacggcagc tggtggccga
    22321 cggctccacc gtgctgctca ccacccagta cctggaggag gccgatcaac tcgccgactc
    22381 catcaccgtt ttcgacaagg ggcgcaaggt cgccgagggc cgccccggtg agctcaagcg
    22441 tcgcgtgggc ggccagatcc tccaggtccg gcccaccgtg gccgccgatg tgccgcaggt
    22501 cgccgcgatg ctcaccgagc tcaccggaca cgcccccgcc cgggactccg gcgtcctcac
    22561 cgtgccggcc gacgacccga tgatcgtcgc ggcggtcgcg cgccgcctgg acggcgtcgg
    22621 catcaccgcc gacgaactcg gcctgcgact gcccagcttg gacgaggtct tcctcgccct
    22681 gaccggacac gcgcccgctg tcaccggcga ccagcccgtc gccgtctgac ttcgcggccg
    22741 cccaagaccg cccccagctc cgtcgactcc cccagccgcc ccgattcccc tggttcccct
    22801 gactcccctg actccgtgca gactttcccg agaggacccg ccatgagcgc ccagcccctc
    22861 atcgcaaacg ccgagcttcc cggccgcatc ggcctcgcgc agaccgcgcg gcacagcctc
    22921 gccctggccg gccgcggcgt caccaagttc atgaagtcgc cgatccagct ggtcgacgtg
    22981 atcctcaccc cgatcatcag tctgctgatg ttcatctacc tcttcgggga ggccatgtcc
    23041 ggcggcgaca ccgacggcta tctgcagctc gtcacgcccg gcgtcatggt catggccgtc
    23101 ttccaggcca gcgtcggcat cggtgcctcg ctctgcgcgg acgccagtac cgggatcttc
    23161 gaccggttcc gcagcatgcc gatcgcccgc tcgagcccgc tgatcggcgc cgtcctcgcc
    23221 gacatcgtcc gctatgtcgt ctgtctgggc accctggtcg tcctcgccct gatcatgggc
    23281 taccgcgtcg aggccggccc ggtcgcctcg ctcaccgcgc tcgccctgct cgtgggcttc
    23341 gccctcagct tctcctggat ctcggtgtac ctcgggatgc tcatcaagaa ccccgcctcc
    23401 gtacagggcc tcatgaccat cctgatcctg ccgctcacct tcgccagcaa cgtcttcgtc
    23461 ccccgggacg acatggccgg ctggctccgg gcctggtccg acgtcaaccc cgtctccctg
    23521 gtggccgaca cggtccgcgg tctgctcaac ggtggcccgg tggccggttc cctggccggc
    23581 accttcgcct ggatggccgg cgtgatcgcc gtcttcttcc cgctggccat gcacgcctac
    23641 cgcaagaacg ccggatgatc ctccggtgac cgacccggcc gggcgaggtc cgcaccccgt
    23701 gtgcggacct cgcccggccg tccgcatggc cgcgcacctc gtcagagccc cggtaccgtc
    23761 cgcaaggtct ctgcctccag ccaccgcagc gcgtcctcac gggagtacgc ggccccgtcc
    23821 tcgaacgcct tcctgaagcc ctcctcgccc agcgtcgcca cgatgcggtc gacgagctcg
    23881 cgccactccg gctcgcccca gtcgaaggcc ccgcgcatca cctggctcat gccgagcgac
    23941 ctggcgcctt cttcgggggc gccctccaat gccctcagtc cgccgagcag ttcggccacc
    24001 caggcgagcg ccgcgcccgc tccctggccg aacagggcgc cggccgcctc gggcagcaga
    24061 gccctggccc gcgccgcgtc cccctcggcg agacgattct cgacgcgggt gctgacgatc
    24121 aggtcgcgag ccagttccct gagggagggg cgccgagcgc tcagcgcctc gagacggtcg
    24181 agggtcgcgt cggcctgcgc caggtcaccg gacctgcggt acacgttggc caggcccacg
    24241 aggatgttgg cctccaggcg cagctgtccc tgctcgcggg cctgccggtg ggcggcgtgc
    24301 agatcgcgga aggcgcctgc caggtcgccg ctgcgccgcc gctcgcgggc gagcctggcc
    24361 ttgctgaggt agaggtagtc ctcggtgccg agctcggagc tgagtgccac ggttcgttcg
    24421 aaggtggcga tggcctgcgg atactcgccg cgcagcgagt ggtcgcggcc gatcgggagc
    24481 aggctcatca cgagccccca gcggtcgccc acctcctcga agccgcgcag cgcctcgatc
    24541 cgggactcgg cgccggtgac cagatcaccc tgttcggtga gggcgaagtc ccgcgccagg
    24601 tgggcgctgg cgcgcaccca gggatcgggc gagtcgagcg cgctccgctc cgcggcttcg
    24661 cccgaccccg gcgcgcccgc ggggaaggag acccgggaca tccgcaggag cagtacggcc
    24721 gggtggaact cccgtgcggt cgcagattcg ccctcgacgg ccggacgttc gccgccccct
    24781 gcccgtacgg cgcttcgtgc ccgtacggaa tgccgttcca gtacggcatg gcgtaccggt
    24841 acggaatcct gtacccgtac gggttccggt gccggtacgc cttcccctgc ctctgcggtg
    24901 tccgacccgg cgacctccgc cagatacgtg tcgagccggg tacccatccc cctgatcccc
    24961 cagtaccaga acatcgcctc ggcgaatcga gcggccaggc tcgcgtcccg ggcgtcgacg
    25021 accaggcgca gcgcgaggac gaggttgtcg tgttcggcgt cgaagacctc gatcgcccgc
    25081 agctgttcgc cggtacgaag acggggttcg tgttcttccg cgagggccag gaagtaggcg
    25141 gcgtagcgct tggtgagggc gtccccggac tcggcgtcgg caagctttct cgccgcgtac
    25201 gcgcgtaccg tctcgagcat ccggtagcgc ggctcgcccg cgccgtcgtc ggcatggtcg
    25261 accagcgact tctctaccag ggcgtccagg acgtacggga tgtcggcggc cgggagcgac
    25321 gggtccgcgc acacggcttc gagcgcgggg acggtcgccc cgcccgggaa caccgacagc
    25381 ctgcgggcga ggatccgctc gggttcgtcg agcaggtccc agctccactc gacgagcgcg
    25441 agcagcgtgc gctggcgagg cagggcggtg cggctgcccg aggcgaggag ccggaagcgg
    25501 tcgtcgaggc gacgcgcgat ctgctcgacg ctcatcgagc ggagcttcgc cgcggccagc
    25561 tcgagggcca gcggcatgcc gtcgagccgt cggcagatct cgaccacggc gtcgagggtc
    25621 atgtcgtcga gcgtgaagtc cggccggact ccggcggccc gctcgacgaa gaggcggacg
    25681 gcgggcgatt gcgcggcctc ggcgggctcc ggcgatcccg tcggtacgtc gagggggccg
    25741 aggtggcaca gggactcacc ggtgatggcg agagcctcgc ggctggtggc gaggatccgc
    25801 aactccggca tctggtgcag gagttcggcg gcaagctccg cggccgcgtc gacgaggtgc
    25861 tcacagttgt cgagcagcag cagggcgtcg ccgctgccga agagcccggc catgcgctcg
    25921 accgggccgg ccggccgccc ccggccggca tcgtagaggc ggccgtcggt cgagctgagg
    25981 gcgccgagca ccgcgtcggc cagccggtcc ggtgcgctca ccccggcgag cggcacgaac
    26041 cagacccggc cgcgcgcgtg ggcccggtcc cgggtggccg cttcgaagga gaggcgggtc
    26101 ttgcccgccc caccggggcc gacgatggtg acgagccggc tgtgggccat ttgcctgccg
    26161 agccggctca gttcgtcgtc gcggccgacg aagctggtca gtctcgccgg gaggcggctc
    26221 gcggcggcct cggcccgccc ggcgggtgtc tccaactcgc ctcgcagcag ggccagatgg
    26281 acctcgcgca gctcggtcga ggggacgacg ccgagctcgt cgtcgagccg ctcacgtatc
    26341 gcctcgtaca ccgcgagggc atcggactgc cgtccggccg cggagagcgc ccgcatccgc
    26401 agcccggcga cccgctcgct caacggcctt tcggcaccgg ccgcttcgag gtccgtcagc
    26461 acttctccgt accgtccgag ccgtagctcg gcatcgcagc ggtcctcggc cgccgcggtc
    26521 cgcaggccgt cgagccgggt cgccacgggg ccggcgaaag gagcgtccag gacatcggcg
    26581 agcgcggatc cctgccagag gccgagggcc gttccgagca gcgaggcggc ctggccggcc
    26641 cgtccggccg cgagttcccg gcggccccga gcggtcagat cctcgaagcg gtgaacgtcc
    26701 acgtcctcgg cccgcaccgc gagccggtag ccgccgggcg cggactccac cgccgcggac
    26761 ccgctcaacg ccctgcgcag ccgggacacc agcgcctgga gcgcgttggc cgcgtcgttg
    26821 ggcggctgtt cgccccacag gccgtcgacg agggagtcga cggacaccgt ccggcccgct
    26881 tcgagggcga gcctggcgag gagcatccgc agccgggcgc cacccacccc gaccggcgtc
    26941 acatcgtcgg cgtacacccg aatcggtccc agcagcacta cgcgcaccac ggcggtctcc
    27001 ccctccggac cgacccgtcc ctggcgtgtc gatcatccct tcaacgccgg gtcagcatca
    27061 cccaactgac gtctccagta aagcgaaggc gcaccgtacg gcggcgcgga cgggccgcgt
    27121 ccgtcgtgcc gcgttcgtcg tgccgcgtcg gggcgacggt ctccgtgccc gcggccaccc
    27181 gctcccggga acgcggcgac agcagcgcga ccagccaccg gcgcggcgtc ggacacgtgg
    27241 tgcggtgtcg ccgaccgatc gcccgaggtc accggctcgc aggggcgcgc gcggcctggt
    27301 ggagcagcct ggcgctctcg gcgttcagcg tgtacgcacg cggtctggct gtcaccggag
    27361 ggttccggac gcccgcgctc tcgacggccg tcggtttcag gcgacggcgc ggggccgccc
    27421 ggcgggcgtg ggaggctcgc cgaggcgttc gagcagcagt ccctcacggg tggaccaggg
    27481 gcagatctcg acattcctga ctccgcaggc ctccatgagg gcctgtgcga tcagggctcc
    27541 ggccagggac tgttcggcgc ggtgccggga gatgcccggc agcttggcgc gacgggacgg
    27601 tcccgcgtcg gccagcaggg agaccgatgt gcgcagttgg ggcagcgcca gcagccgtgc
    27661 gcctcggggt gacttgctct gggcggcggc gagccgggcg agctgttcga aggtcttgga
    27721 gcaggccagc actcgcccgc ccggttcggc ctgcggcagg ccggggacac cctccaggga
    27781 ccggcgcagg tgctgccgga tctcggccag acggcgcggg gacggcgcga tgccgccggg
    27841 aagccagtcc cgggtgatcc tgcgggcgcc cagcggcagc gagtgcacga cgccgggctg
    27901 ctctgcgctg ccggaggcga tctccacggt gccgcccccg atgtccagga ccagcagccg
    27961 gccggccgtc gggcccgccc aacggcgggc ggccacgtag gccagccgcg cctcctcctc
    28021 gccggccagg acgcgcagcc gggtgcccgt ggtgcgtgcc accctcgcga tgatctcgtc
    28081 gcagttgggc gcgtcccgga tgacggaggt ggcgaacgcg aacacgtcct gcccgcgcag
    28141 ccgcgggtcg gcgtcgacgg cctcggccac ggcccgctcg acgctcctca ctcctgcctt
    28201 gtccagccgc cccttgcggt cgagggtctc gtgcaggctc aggcgtacct tgcgggagaa
    28261 caccggctcc aggtcggcgc ccgggcgccg ccgcaccacc gtcagcagag cactgtggca
    28321 cccgacatcg agcacactcg cctgccgcat cccatcgcct ccttctggcc ccgcgcccgg
    28381 ccggaccggc cttctccgat cctccgccgg cgcctcggac ggcgcgacgg gttttccggc
    28441 ccaccgcgtg agcataccgt caccacccgt gcaccctccg ccccaggccg cgcgcgacga
    28501 cggggtccgg tccgaccgac tgctcgtcgg gacctcggcc acctcccccg aggaccgcgg
    28561 gggcgagcgt gcgggagcga ggtccgggcg ccggggatcc gcgtcgccgc gcacggtccc
    28621 ggcatgctta ttggattgca gcggaccggt ccggccggat aggaaacctg catgctcaaa
    28681 ggcgacaagg tcgggctcag ggcccggcac gaggacgaca tcccgatcct gcggaccgag
    28741 ctctacgacg acgtggtcaa ctcctcgcgg gcggaaggcg ggccgtggcg gccgatcacg
    28801 cccggctcga aggatccacg gctcgtggtg gacgacaagg agcagggcag cgtcaagttc
    28861 tccgtggtgg agctggaggg cggcaccctg gtcggaaccg cgacgctgtg gggcatcgac
    28921 aaccacaacc gggccgcgca catcggcctc ggactgctgc cctcctcccg cggcaagggt
    28981 tacggcaccg atgtggtcgc ggtgctgtgc cagtacggtt tcgtcgtgcg cggcctgcag
    29041 cgactgcaga tcgagacgct gtcggacaac gccgcgatgc tgcgctcggc cgagcgcaac
    29101 ggcttcgtcc gcgagggcgt gctgcgctcc tcggcctggg tgatgggcga gttcctcgac
    29161 gaggtgctgc tcggactcct cgtagaggac tggaagcagg actcgaaggt ctagatcgcc
    29221 gtccggccgc cggctgcggg ccggggaccg tcggctgcgg gccggggacc gtcggctgcg
    29281 ggccgggggt cccgcagggt cggcccgagg cccgccccac accccgctcc gtcgctcggc
    29341 cgggtggggc gccgggccac ccgtgcgccg gacgtccgtc ccgtcgtcag gggccggtga
    29401 cggctcccgt cccggctcgg ggggtcacgg gacgggagcg cgtcacccgg ttcttcctcg
    29461 cgtcacggcc gtacggatgc acgggtgtgg gaggggcgct cgtgaactcc tcaggcggtc
    29521 ggggaggtga gccgtacggg gagttcgaag aggtcgttct gggtcaccac cggcttgttg
    29581 cgcagggccg acggggccac cgccaggtcc agcccgggga agcgggcgta cagcgcgggc
    29641 agcgcgacgc ccgcttccag gcgggacagt gcggcgcccg ggcagacgtg cgggccgtgg
    29701 ccgaaggata tgtggcgggt gcgggtctcg cgggtgatgt cgaagtcgcc ggccgagggg
    29761 ccgtgtgcct cctcgtcgcg gcctatcgcg ccgtaggaca cgatgagcgc gtcgcccgcc
    29821 gggatgaccc ggtcgccgac cgggacgtcc tcggtggcga accggatcag cacgtgcgac
    29881 gtcggcgtcg accagcggag ggtctcctcg atcaccgcgg accagtccac cgcccccgac
    29941 aggaccagtg cccgctggtc ggggtgggcg gagaggttga cgacggcgtt cacgatcagg
    30001 gagatggtgg tctcgtggcc ggcggcgacc atcagctgga gcgtggagac gatctcctcg
    30061 tcggtgagcc ggtcaccgtc ctccgaggcc aggacgagcg cgctggtcag gtcgtcaccg
    30121 ggctcggcac gcttggcggc gacggtctcg gccatgatcc cggccagttc gacgagggtc
    30181 gcgacgacct ccgcgggcgg ggtctgggtg gagaagaact tctcgaacag caccttcagc
    30241 cggggcagcc ggctctcctc gatgcccatg aggtcggcga cgacgtacat cggcagcggg
    30301 taggcgaact ccgccttgag gtcgacgact tcggcgtcgg cgggcagccg gtccagcagc
    30361 cgtccggtga gttcggtgat ccgctcccgc atcgcctcca cccggcgcgg ggtgagggcc
    30421 tgggcgacga ggccgcgcat cctgcggtgg tcggcaccgt ccacggtcag catggaacgg
    30481 ccggggttga ccaggccgat cagcggccag tcgggcggga tctcgccgcg ctgccaggcg
    30541 ccccacacgt tgatgtcctt gacgagccgg gggtccgtca gcagcgcctt ggcctcggcg
    30601 tgccgggtga ccgcccacac cggcaccccg ccgggcagct cgaccgcggc cagcggtccc
    30661 gccgcccgca gcttggcgct ctccccgtcc aggtcggtga cgaacggatc caggggaatc
    30721 cgcagctctt cggttccgga cgtcatgatc agttgcctcc cagggcaggg gtgggggtga
    30781 accgcacggg cagttccgtc aggccgcgca gccagggcga ggggcgacgg gtcagggact
    30841 cggccgggac gtcgagatcg atgtcgggca gccggtccag gacgacctcg atccccgtcc
    30901 gggcgatgac ctcggcgacc tcctgggccg ggaacgggca gcggtgctcg ccgtggccga
    30961 aggagaagtg ggcgttgttg ccgccggtga gttcgtttcc gacgggacgc acctgggggt
    31021 cggagttggc tgcctggaga ccgaggatga gcaggtctcc ggcccggatg tgctgcccgc
    31081 cgaggtgggt gtcccgcgac gcccagcgcc cggcgacgtt ctggctgggc gtgtcctccc
    31141 agagcacctc gttcatcgcc tccgcgacac tgttgcggcc accgaagagc gaagcggcga
    31201 aacggccgtc ggtgagcatc agccgcagcg agttgccgat ccagtcggcg gtgggctggt
    31261 gcccggccgc catcatcacc atgaggtcct gggcgacctc ctcgtcggtg aagccaccgg
    31321 ggtcggccag catgcgcgag acgacgtcgt cggcgggcgc ggcccggcgc gcggcgagca
    31381 actcgcccat ggaggaggcc agatgactct gtccggcgag agcgcgttcc cggccgtcga
    31441 tcatgtcgtt gagcgcggtg accaggcccg gtccgtcctc gtcggagaag ccgtacagcc
    31501 gcgccaggac gcgtacgggc agcagcatgg cgtactggcc gatgagatcg gccgttccct
    31561 cggcgcacag ggcgtcgatc agctcgtcgg cgaaccgctc ggcgtggcgg cgcagccggg
    31621 tcgggtcgct cgcctccagc gcgttgctga tcatggcggc ccgctcgcgg tgccgctcgc
    31681 cgaccgtgta gaggatcgac ggctgcttgc ggccgatcat cggcagcagg ggccagtcac
    31741 cggggatcgt gtcccactgg ttccacagct ccgagtcgcg gctgaacagc acgggatcgc
    31801 ccgtgacctg gtgcagttcg cggtagccga ggacgagcca ggccgggacc ccgccgtcca
    31861 gcaggacggg ggtgacggcg ccgtgctgcg cgcgcatctc ccggtacagc cgggcgggtt
    31921 cggtctggaa gcgcggaccg ctgagcggaa cggcgtcggt gctcacacga actcccgtgg
    31981 tgaagcggcg gtgtgggccc tctgcccggc gtaccggctc tggatgtgct ggacgagcgt
    32041 gatgaggacc tgcttgctgg actcccgggt acgggcgtcg cagtcgatca ggggcacctg
    32101 cggatcgagg tcgagcgcct cgcggacatc gctgtgcgcg tggcgggcgc cgccgaagtc
    32161 gttgcaggcc acgatgaacg gcgtaccgtg gcgctccaga cggtcgatgg cgtaccagga
    32221 gtcgtcgatg cgccgggtgt cgaccaggac gaccgcgccg agggtgccgg agaacagccg
    32281 gtcccacagg aaccagaagc gttcctggcc gggcgcgccg aagaggtaca gcacgttgcg
    32341 ctcgtcgagg gtgatccggc cgaagtcgaa ggccacggtg gtcgcggtct ttccgcggat
    32401 ctcgctgatg tcgtcgaccg tctcgccggc cctcgtcatc gtctcctcgg tgttgagggg
    32461 acggatctcg ctgaccgaac ggaccatggt cgtctttccg acgccgaagc cgcccacgac
    32521 gacgatcttc agaccgttgt cggcggtggc acccaggggg gtgcgcacgt cagaggttgc
    32581 ggagtccaac gagcacctgc tccaagacgt cgggatcggg aagggcggag ttgcgggggt
    32641 ggcgtgcgct gacccgtccg gcggcgagca ggtcggacag caggatcttg gtgatgctca
    32701 cgggaagccc cagttcggcg gcgacctcca ccacggcggt gggcgcccgc gccagtctga
    32761 ggaccgccgc gtgctcggac tgcatgccga cggtggggtc gctctcggcc accaccagcg
    32821 tcaccaggtc gaaggggctg tcgggccccg agcggctgcg ccccccggtg agggtgtaga
    32881 gccggtcggg ggcgtcgtcc ctgccggggc gcttcacgcc gtgcgaggcg gggccgtcag
    32941 gtgctctccg agctgttcca ccagctcgct catgttgtgc ccgacgagtc cgggttcggc
    33001 ctcctcggtg gtgaccacgg ccaggtgcgc gccttcaccc gcctccacga tgaacagtgt
    33061 tccgccgtag aactcggtca tcgaggagcg cacgcctccg ctgccgtcgc cgaactcgac
    33121 cgaggcgccg tgcgacagcg actggatgcc ggcggcgatg gcggcgagct ggtcggcctg
    33181 gtcgaccgtc agttccgggg tacggcacag cttcagcccg tcgcgcgaga gcacgagggc
    33241 gtgccgggcg cccggggtgc gctcaaggag tccttctatg agccaggtga gcttctcgtc
    33301 ggcggtggtc gtgccggtca tgaggtggtg tcgccttccg ggtgcgaggg ggtggaactg
    33361 ccgggcgccg tctcggtctg cggggacggc gtggtgtgcg agtcgtcggg ggcggccggc
    33421 agcgggtgcc cgcctgtgcg ttccgccgga ccggcggcgc gcaccgcctg gcggaaggca
    33481 ccgaagcggt tggcacggac gcggatgtcc tcgggcgggt ccgtgcggcg ctcggcgctc
    33541 tgggcggcgg cgcgcgcgct ctccgcggcg gccagggtgc ggccgcgccg gcgcttgggc
    33601 agcccgtcgc ccgtctgcgg ggcggcgtcg gcgccggcct cctgcggcgg gacctcctcg
    33661 ggagccgtgg cgacttcggc gggggcgggc gccccgaggt ccggcagcgg ggcgcgcgcc
    33721 ggggcgttgc gcgcgggcgg gtccgccggg cgccgcacgg gggacggcgc cgccgtgagg
    33781 atgtcctggg ggatgagcat gagcacaccg gtgccgcccc gcgcggaggg ccggaaggac
    33841 accttcattc cgtgcttgcg ggagaggcgt cccaccacgg cgaggccgag ccgggtgccg
    33901 gtgagtccgc cgagtccgcc cgcgtcgccg gagactgcct gttcggcgcg gcgcagctgg
    33961 acgtcgctca tgacgagccc gctgtcctcc accgacacga tggcgccggc cggcacctcc
    34021 tcgacgtaga cgtgcacctc ggcgttggga ggcgagaagt tggccgcgtt gtcgagcact
    34081 tcggcgagcg cgtgcatcac gccctcggcc gcgtgcccgg ccaccgcggt gtcgctgacg
    34141 gagtgcaggc ggatgcgctg gtagccgctg atccggccca tggcgccgcg cagcacggac
    34201 tccatggaga tggggcgcgc ccaacggcgt cccgatcgcg cgccggtgag gacggcgacg
    34261 gagtcggcga gacggccggc ctgggcggtg cggtggtcga ggtgcagcag gtcggcgagg
    34321 acgtcctcgt cgctgtgccg ttcctccatg gcgcgcaggt cggccagggt gccggtggcc
    34381 agtgcctgca tccgggccgc ggcgttggcg gtcgcggcga tcgcggtgtc gcggtcgccg
    34441 agggcttggt cgagctgccc ggagagcctg cggacctcgg ccgcgagccg ggcccgttcg
    34501 gcctcggcct cctgggcgcg tacggcgcgt tccctggtga actcctcggc gagccgggct
    34561 cgttcgtgtg cggtggcgtc ggtgtgccgt tggtgttcgc ggcgccatcg ttccgcctgg
    34621 aggtcgcgct cctgggcggc ccgctcggcc tcggcggtcg cggtccgcag cgcggcacgt
    34681 acggagcgcg tggtgcggcg cgcgtgtacg gcgacggtga cggccacaca cagcagaacc
    34741 gcggcgatgg cgccgccgca gcccacgagc gcctgcgccg actcgggtac ggacgtgacg
    34801 gcccctacga cggcgagggc ggacagggcg gcggtcaaca ggggtagggg cagcagcgaa
    34861 cggatggtgg atcggtcgcc ggaaggggcg ggcgcggtca tcgctcaggt cctcgggtgg
    34921 ccgctcggga acgcgaccct tgtgttgtcc taaggggcag atagtgcaca gaagtctgta
    34981 gtcggtgatc aaccgggcgt cactatacga gagtttcgat caccccgaac agtgttcgac
    35041 cagcacagtt cgcgaactcg ccgtcctggg gcacctgatg ccggcacctg acgacccgac
    35101 tcgacggctt cctccccccg gctgaccaga gattctttgt gcgggctgtg cgagttgagc
    35161 ggccgggcgg cccgaccgga agcctcgccg actcggcccg gatgtccgca tgtggagtcc
    35221 gcggccgggt ggctgcggct cggcgtcgac ggctgcgcgg tcctcgaact tctgccgctc
    35281 ggcgcggtac gtcggggaag ggacggcagt cagtcccgca cacgacagga gcccgacacg
    35341 cgtgtccccc gtcgccgacc gggcatacgc agccgaggcc gtcggcatcg gcatcggcat
    35401 cgtccggagt ggcgagccga tcgccctgcc gccaggctgg cggtgacggc agaggtaccg
    35461 gcacgcggga cggacggaca gacgcgcaaa gggactggtt gcacatgcag atcgatctgg
    35521 cgggacgcac cgccctggtc acgggctcca cgcagggcat cggcgcggcg atcgccgccg
    35581 ggctcgcacg ttccggcgcc cgcgtagggg tgaacggccg agacgagcag cgggtcgccg
    35641 agagcgtggc gcggctggcg acggaggtgc ccggagcctc cttcgtgccc gtggccgccg
    35701 acgtggcgaa cgaggagggc gcgcagcgag tcctggaggc gctgcccgag gtggacatcc
    35761 tcgtcaacaa cctcggcatc ttcggctccg ccgacccgct gaagatcagc gatgacgagt
    35821 ggcggcgcta cttcgaggtg aacgtgctgg ctgccgtacg gctgacccgg ctgtacctcc
    35881 cgggcatgac ggagcgtggc tggggccgga tccagtacat cgcgagcgac tcggcggtcg
    35941 tcatcccggc cgagatgatc cactacggga tgtccaagac cgcgctcctc gccgtcggcc
    36001 gcggcttcgc gaaacaggcg gcgggcacgg gggtgaccgt caactcggtc atcgccggcc
    36061 ccacccacac cggcgggatc gaggacttcg tctacgaact cgtcgaccgc gacctgccct
    36121 gggacgaggc ccagcgcgcg ttcatgcgga agcaccggcc gcagtcgctc ctgcaacggc
    36181 tgatcgagcc cgaggagatc gcccacatgg tcgtctacct cagctccgac caggcttcgg
    36241 ccacgacggg cggggcactg cgggtcgacg gcggatacgt cgactcgatc ctgccctgac
    36301 gacgcgggcc ctgcggtcgg cacccgtcgc cgggaagaga cacagcgacg gtccgccggc
    36361 cctggtcgtc ctgcgcgact cagggatgca gggtcggccg gtagacgagt tcctgggtgt
    36421 ggccgtcgag cgtccggtgc tcgatcagtt cgaggtcgaa gtcggccgaa ccctggaaga
    36481 tcgggtccag cccggtccga ccggtgatca cggggaagag cgtcacctgg acgcggtcga
    36541 ccagaccggc ggccatcagc gcccggttca tcgacaggct gccgtgcgag cgcaacggca
    36601 ccgcggactc ctccttgagc cgggcgacga cgtcgacggc atcgccgctc aggagcttcg
    36661 cgtccggcca gtcgagaggt tcctccagcg tggtcgacac caccgtcgcc ggcaggctcc
    36721 tcatccgcgt gacccatggg tcacgcacct cggactcctc ggcgctcgag gccagcatcc
    36781 gtgcgaacgc ccggtaggtg ttggccccga agaccatccg ctgctcctcg gcgtacaggc
    36841 cgagtcggtg gtcgagcagt tcggggccct gcttgcccca gtagccggtc cagtcgccac
    36901 tggcggctcc gaagccgtcg aggctcgaaa agacgtcgaa ggtgtaggtg gcggtcatga
    36961 tggtctcctg gatcgagtgc ggttgatcgc gtcctgggaa tgcagaccga cgaccgcggc
    37021 gagactcatc gtccttctcg cttcgccttt tgcggccgtc acatccacag cacgccgtcg
    37081 tcctcgtgct cgcgcacgcg gaacgcgatg atccggcgca gcagggcgct gggcacgggc
    37141 tcgccgtagg ggagcttgac cgagcccttg ccggtggcga agccggcgag gtcggcgtcg
    37201 aacgcctcgc gggtgctggg ggtgaacacg acgttcgcgt gcttcgcgtg gccgctggcc
    37261 atgaacagga tcgtgccgga cgggtggacc caggcgggat ggccccactt gatcgcctcg
    37321 ctcgccgcgg ggaccgcctc gagagccagc gcccgtacct gttcgagcac ctcgcggccc
    37381 tgccccgcga agccctcgat gtactcgtcg accgtctgcg gcttccccat ggcgccagtc
    37441 tggcaccgcg cccccttcga cacccttcag ccgttcgccg ccgggcccgt acggacgacg
    37501 gcctggtcgc cgtgcgggcc gaacaggtgc aggatttcca ccgcttcggc gtcggcgggg
    37561 ccgaaccagt ggggttcgcc ggtgtcgaac tcggccacct cgcccggccg gagggtgatc
    37621 tcgcgctccc ccaggatgag ccggagccgg ccggcgagca cgtagagcca ttcgtagccg
    37681 gagtgggtga ccagtcgcgg ttcgcggtgt gagagcacct gcttgaagac ctggacccgg
    37741 cccgggtact gcgtcagcgg gacgaggacg cttccacgct cccggctgcg gggcttgaga
    37801 tggactcgcg gatcaccggt ggccggagcc gtcaccagtt ggtccagcgc cacgcggtgg
    37861 gctcgggcca gcgggatgag gagatcgagc gtggggcgcc gtcggcccga ctccagacgc
    37921 gacagcgtgc tcacggagat tccggtgtcc tccgacaggg cttcgagggt gagaccgcgg
    37981 tcgcgccgca gggcacgcaa ccggggcccg atgctgtcga ggagttccgc gaggtcggcg
    38041 tccatacggc catttttgca gtcttcgcaa agttcctggg ccgggagcct cccccggtcc
    38101 gagcctgggc gcagccgatc ccgcccgacc gacccgaccg gcagacccgc agacccgcag
    38161 acccgcagac ccgcagaccc gtagacccgt agaaggggta actctcgtgc tcacgacatc
    38221 cctggccgct ccgccctccc cgctcagcgc gcgcagacgc tggacggtcc tggccgtctg
    38281 cgcgctcagt atgttcctgg tgggtgtgga caccaccatc gtcaacgtgg gcctgcccga
    38341 gatcgggcac ggcctcggcg tcggcaccca cggtctggag tgggtcgtca acgcgtacac
    38401 cgtggtcctg gccagcctcc tcatcgtctc cggcgcgctc gcggaccgct tcggacgccg
    38461 ccgggtcttc cagtgcggcc tgctcgtgtt cggcctggcc tccctcatct gcgccctcgc
    38521 cccgtccctc ggcgtgctgg ttgccgcccg ggccgttcag gggatcgggg cctccatgct
    38581 gagcccggtg gccctggcga tcgtggtgaa cgcgatgccc gacccaaggg aacgcgcccg
    38641 ggcgatcggc gtgtgggcgt cggtgttcgg gctcagcatg gcggcgggcc cggtcaccgg
    38701 cggggcgctc atcgccgcgt tcggctggcg ttcggtgttc tggatcaacg cgccggtcgt
    38761 cgtcgccgcc ctggtcctgg tcgccgtgtt cgtgccggag tcccgcgccg agcgcgcgcg
    38821 gcgcctcgac ctgcccggac aggcgctcct caccgtggtc ctgggcctgt tcgtcggcgt
    38881 cctcgtcgaa ggccccggta tcggctgggc ctcgcccgtg gcgctcaccg gctacgcgct
    38941 gatcgccgcg acgacggcgg ggttcgtcct ggtcgagctg cgccgcgctg aacccctgat
    39001 ggacctcggc ctcttccgcc ggccgccgtt cgccacggcg gtgctgggcg ccatggcggt
    39061 gttcgccgca ctgaacgtga gcatgctgct caacaccctc tacctccagc acacccgtgg
    39121 ctggacaccg ctcgcgagcg gcgccgcgac cctgcccatg gcactcgggg ccaccctgtg
    39181 cgcaccctgg tccggcgccc tcgtagggcg cctcggaccg cggcgtccac tgatcctcgc
    39241 gggcaccttc accacggcgg gcggtctgtg cctgacgaac ctggaccagg acacgagcgt
    39301 gccgctgatt ctcctcgccc acctgctgat cggcatcggg ttcggcttcg ccaacgcccc
    39361 cctcaccaac accgcggtca gcggtctgcc gcgctcccgg gccggcgtgg caggggcgat
    39421 cacctccacc gcgcgccagg tcggcgcggc ggtcggtatc gccctcgccg ggggcctggt
    39481 cgcggacgcc ggccccaccg gcctcgccgc cgcgtcacat ccgggatggc tgctcgtggc
    39541 ggcctgcggg ctgctcctct tcgtcgtggc ccgcgcctcg cagcccgcgg ccgtccaggc
    39601 tcgctgaccc cacgggcggg acccacggcg gcgcggccct ccggaggccc ttcaggtgtc
    39661 gtacggcgac gacgccttca agagtcgggc ggcggcgaac gacgccttca taggtcaggc
    39721 gccggcgagg gagagcttca ccgcgaaccc gaggaacagc acgccggccg ccgaggtggc
    39781 gcccgccgta aggcgcttgc ggcgtcggaa ggcgccggcc agccgggtcc cgccgaagat
    39841 cagtgcggtg aggtacagca cgctggcgag ctgggccaag acgccgagga cgacgaagga
    39901 gagcgccggg taggcgtacc ccgggtcgac gaactgcacg aagaaggcga caaagaacag
    39961 gatcgccttg gggttgaaca ggctgacgac cagcgcccgc cggaagggcc gctcgacgga
    40021 gacctcggcg gggccgtcct cggcgggcac ccgctcacgg cgcgtccgcc acatcctcca
    40081 ggcggcccgc agcatcccga ccgccagcca ggtcagatag ccggcgcccg cgtaccgcac
    40141 gatcgcgaac agtacggcgt tggcctggag cagcgaggcc accccggccg cggacagagt
    40201 catcaacacg gtgtccccgc accacacgcc ggtcgcggcc gtgtacccgg cccgtacccc
    40261 gcgccgcgcg gcgacggaca ggacgtaaag agagttgggc cctggaagga ggactatcag
    40321 gacgagtcct gccaggtagg tgggaaggtc gacgactccg aacatgtgca gcagtgtcgc
    40381 atgcgcatac gacacctggc aggggccgcc cacctcacgg aagccgccac ggcgatgatc
    40441 acgtcgaaca tgaagggtgc gccttcgccg ccgggggccg gcgaccggag aaccccgggg
    40501 acgtcgcccg cggtgaagtc gcgctcggcc gtgtcgttcg gcgacggctc ggcggtgaac
    40561 tgcgaagagt tcatgggtgt tgcctttcgg gagtgccttg tggtcaaggc actcccggcg
    40621 acgcctgtgt cagtcgccgg ccgtgacggg aagggggagc gcccacgtcg atacagcgtt
    40681 catgggtctc acctcctcgg gcggtgtcgc ggtccactgc aggcgtgagg ctgtcgcgtc
    40741 cgcgtcgtcc gcgcgcaccg gtacagccga cgtgcggccg acgtgcggca gacgtgcgtg
    40801 gagaagtcga gggagtgggg gcaaccctgc ccccgcctca tgagtcacac acgcgccatc
    40861 tgattctcat tggtccggaa agggccccac cctctgtgat gactcgtacc cggctgaccg
    40921 cgctcgccgc gacggccgcc ctcgccgcca ccggcgatct gatgatcgcc gccccggcct
    40981 ccgcggccgt cacctgcgcc tctcccgtct ggagagcgca gtacttcggc aacaccacct
    41041 tcagcggcac gccgaaactg accgcctgcg acgccgccgt caacgagaac tacgggtacg
    41101 gcgacccgac gggcgtcacg ctgcccaagg acaacttctc cgtccgctgg tccctcaccc
    41161 gggacttcgg ctccggcggc ccctt
//
