LOCUS       NZ_LMEQ01000004        24001 bp    DNA     linear   CON 07-JUN-2024
DEFINITION  Streptomyces sp. Root1310 contig_12, whole genome shotgun sequence.
ACCESSION   NZ_LMEQ01000004
VERSION     NZ_LMEQ01000004.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. Root1310
  ORGANISM  Streptomyces sp. Root1310
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 241947)
  AUTHORS   Bai,Y., Muller,D.B., Srinivas,G., Garrido-Oter,R., Potthoff,E.,
            Rott,M., Dombrowski,N., Munch,P.C., Spaepen,S., Remus-Emsermann,M.,
            Huttel,B., McHardy,A.C., Vorholt,J.A. and Schulze-Lefert,P.
  TITLE     Functional overlap of the Arabidopsis leaf and root microbiota
  JOURNAL   Nature 528 (7582), 364-369 (2015)
   PUBMED   26633631
REFERENCE   2  (bases 1 to 241947)
  AUTHORS   Garrido-Oter,R. and Bai,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2015) Plant-Microbe Interactions, MPIPZ,
            Carl-von-Linne-Weg 10, Cologne 50829, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: A5 v. 20140604
            Assembly Name                     :: Root1310
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001426425.1-RS_2024_06_07
            Annotation Date                   :: 06/07/2024 02:14:31
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,470
            CDSs (total)                      :: 8,385
            Genes (coding)                    :: 8,123
            CDSs (with protein)               :: 8,123
            Genes (RNA)                       :: 85
            rRNAs                             :: 4, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 262
            CDSs (without protein)            :: 262
            Pseudo Genes (ambiguous residues) :: 0 of 262
            Pseudo Genes (frameshifted)       :: 98 of 262
            Pseudo Genes (incomplete)         :: 219 of 262
            Pseudo Genes (internal stop)      :: 20 of 262
            Pseudo Genes (multiple problems)  :: 64 of 262
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 22:32:08
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7382
            Orig. end                         :: 31383
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LMEQ01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24001
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="True"
                     /product="indole"
                     /product="hydrogen-cyanide"
                     /region_number="1"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..24001
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="neighbouring"
                     /product="indole"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..21326
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21326
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[10000:11326](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11326
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    complement(922..940)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.56"
                     /tool="antismash"
     misc_feature    925..943
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 23.37"
                     /tool="antismash"
     misc_feature    complement(929..947)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.09"
                     /tool="antismash"
     misc_feature    complement(942..960)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 23.03"
                     /tool="antismash"
     misc_feature    951..966
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.2"
                     /tool="antismash"
     gene            1080..2210
                     /gene="sucC"
                     /locus_tag="ASD48_RS12615"
                     /old_locus_tag="ASD48_34575"
     CDS             1080..2210
                     /EC_number="6.2.1.5"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="sucC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125666.1"
                     /locus_tag="ASD48_RS12615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34575"
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="WP_057601656.1"
                     /transl_table=11
                     /translation="MDLYEHQARELFADHGILVPRAEVTDSPKEARAIASRLGGRAVVK
                     AQVKTGGRGKAGGVRIAADPAAAELTARQILGMDIKGHTVGSVMVAQPVDVEAEFYVAY
                     VLDRVAGRFLAIASAEGGTEIEEVAATRPAAVARIPVDPAEGVTSAQAGEIAAAAGLPA
                     QTADVLVRLWQVLIREDALLVEVNPLVRTRQGQILALDGKVTLDDNAFFRQSRWGAEAT
                     AHGDPLEAAAAAKGLNYVKLDGEVGIIGNGAGLVMSTLDVVAGCGARPADFLDIGGGAS
                     AEIMADGLSVVLSDPAVKSVFVNVFGGITACDAVAEGIVRALDTVRLTKPLVVRLDGNN
                     AARGRAILDAHRHPLVQQATTMDGAARRAAELATAV"
     gene            2223..3116
                     /gene="sucD"
                     /locus_tag="ASD48_RS12620"
                     /old_locus_tag="ASD48_34580"
     CDS             2223..3116
                     /EC_number="6.2.1.5"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="sucD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125667.1"
                     /locus_tag="ASD48_RS12620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34580"
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="WP_057601657.1"
                     /transl_table=11
                     /translation="MAIYLTKESRVLVQGMTGAEGMKHTRRMLAAGTNIVGGVNPRKAG
                     RAVDFDDRAVPVFGSVVDGVQSTGADVTVVFVPPAFTKAAVIEAADAGIGLTVVITEGV
                     PVHDSVAFTTHAAARGTRVIGPNCPGLITPGQCGAGIIPADITKPGRIGLVSKSGTLTY
                     QLMYELRDIGFSTCVGIGGDPVVGTSHIDCLTAFEEDPDTELVVLIGEIGGDAEERAAA
                     HIRAHVTKPVVGYIAGFTAPEGRTMGHAGAIVSGSSGTAQAKKAALEAAGVRVGATPSE
                     TARLALTVLDEGARRR"
     gene            3217..4758
                     /locus_tag="ASD48_RS12625"
                     /old_locus_tag="ASD48_34585"
     CDS             3217..4758
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006130648.1"
                     /locus_tag="ASD48_RS12625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34585"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_057601658.1"
                     /sec_met_domain="Aldedh (E-value: 1.3e-100, bitscore:
                     330.8, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTLTLRSGTSWPDAWRRCLAVAPEAFREDRVLNLWNASWQADG
                     RTLPATSPVDGTPIAGPPRLDGDTARQAVRAGLDQHRAWRHVPLEERRARIAATLDALA
                     EHRELLALLLVWEIGKPWRLARADVDRAVDGVRWYVDGIEPMLDGRAPLDGPVSNIASW
                     NYPMSVLVHAMLVQALAGNAVIAKTPTDGGVACLTLACALAAREGVPVTLVSGSGGELS
                     RALVRAPEIGCVSFVGGRDTGAAVATAVADLGKRHVLEQEGLNTWGIWNYSDWDALSAV
                     VPKLFDYGKQRCTAYPRFVVQRTLFDEFLAAYLPAVRTLTLGHPLAVEKRDDPYPRLDF
                     GPVINAAKAKELHDQIAEAIDRGAVPLHRGRPADARFLPGQDTSAYVQPVTLLGPPPSS
                     PLHHAEPFGPVDTIVLVDTEAELLAAMNASNGALVATLSTDDRSTYERLAPQIRAFKVG
                     HGTARSRGDRDELFGGFGASWRGAFVGGELLVRAVTQGPTGERLPGNFPDYQLMP"
     gene            4951..5253
                     /locus_tag="ASD48_RS41775"
     CDS             4951..5253
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024854.4"
                     /locus_tag="ASD48_RS41775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_242432580.1"
                     /transl_table=11
                     /translation="MLAEEGTLSLAGAAGRLGVDRTTVAALVDGLEDHGLVERRRSPRD
                     RRRNTVRLTAAGLVCPERGEGRAGPRSAGSPPRWSSRRRPRCCGRRGGSSSRSRR"
     misc_feature    complement(5255..5270)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.94"
                     /tool="antismash"
     tRNA            5402..5486
                     /anticodon=(pos:12817..12819,aa:Leu,seq:gag)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="ASD48_RS12630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="ASD48_34590"
                     /product="tRNA-Leu"
     gene            5402..5486
                     /locus_tag="ASD48_RS12630"
                     /old_locus_tag="ASD48_34590"
     gene            5920..7086
                     /locus_tag="ASD48_RS12635"
                     /old_locus_tag="ASD48_34595"
     CDS             5920..7086
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971679.1"
                     /locus_tag="ASD48_RS12635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34595"
                     /product="ATP-binding protein"
                     /protein_id="WP_057601659.1"
                     /transl_table=11
                     /translation="MTHYIQNPVLWALLVAVLAAVALIVRQRRAARVLRQEIAGLRSHY
                     SALENEYAQSVEAAQEQAEEATKTVLKSAMRTLQGLAAEQQLIVSRLQNKYGESVILQD
                     LLEIDHTNSQFGRRAQSIAVLCDGWLGRARDVASVYDVVRSAQGRVRHYRRVEILSQVD
                     FGITSRAVEPVALALAELLDNATSYSSPDTVVEINIRTVPKGICIVVDDAGVGMNDEER
                     ARADKLLSSERVSGVSALGNPPQFGFAVIGVLSERFGFEVSVDSTSPYGGVRAVLLLPH
                     DLLTNAPEQKEPAPVVPTVAATARSGPEGGLSTSTTADGLPKRRRKRPMAIVPGSASAS
                     TPARSGAETAAIMGAFQRGTQSGRATPASPAEKSSSTRGAGSEGHEVS"
     gene            7083..7484
                     /locus_tag="ASD48_RS12640"
                     /old_locus_tag="ASD48_34600"
     CDS             7083..7484
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971678.1"
                     /locus_tag="ASD48_RS12640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34600"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_057601660.1"
                     /transl_table=11
                     /translation="MNDDLSWMLDSALEIPGALHAVLISADGLLMARTQDFDKDDADRV
                     AAAMSGVQSLSRSLAFFCEDPQMGWRQTLVEFDGGWVFLISAGEGAYLGVSASPDVDMA
                     DITFRMQQLVGQLGKALTTPPRENLGVRS"
     gene            7481..7858
                     /locus_tag="ASD48_RS12645"
                     /old_locus_tag="ASD48_34605"
     CDS             7481..7858
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125672.1"
                     /locus_tag="ASD48_RS12645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34605"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_057601661.1"
                     /transl_table=11
                     /translation="MKGFDELEPQTPELVRPYVITKGRGLPDEGQLSLITLVTAAADHE
                     QRPTRLSPEEQNLLDLCSAGYLSVAEIAGHTQLPLGVVKILLAALTEGGYLITRPPVQR
                     APLADRDILEEVLNGLRAKFG"
     misc_feature    7520..7522
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7833..8426
                     /locus_tag="ASD48_RS12650"
                     /old_locus_tag="ASD48_34610"
     CDS             7833..8426
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358089.1"
                     /locus_tag="ASD48_RS12650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34610"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_057601662.1"
                     /transl_table=11
                     /translation="MVSGPSLDEQAYVRDGATQTAVKILVVGHFAVGKTTFIGAISEIQ
                     PLTTEETMTRAAESVDDLKGVQGKTTTTVAMDFGRLTISDRVVLYLFGTPGQQRFVQMW
                     EDMARGALGALVLVDPERLADSFAVIDLIEQYGLDYAIAVNHFDGAPLRDETALRDALD
                     LLDDTPVVTCDARDERSSADALITLVRHLQDRAH"
     gene            8435..9778
                     /locus_tag="ASD48_RS12655"
                     /old_locus_tag="ASD48_34615"
     CDS             8435..9778
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125674.1"
                     /locus_tag="ASD48_RS12655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34615"
                     /product="cytochrome P450"
                     /protein_id="WP_057601663.1"
                     /transl_table=11
                     /translation="MDQPTAPVPPPGCPAHQAGGRVPLHGLEFAADPQAYYSYLRHFGP
                     TAPVELAPGVEATLITDYAVALQLLQDSGAFRKDARRWRDLNEGRVPPDSPVAPLLSYR
                     PNAMFSDGAEHLRLRQAITDSMARVDTRKLSRTTEQVSNYLISQFGSRGSADLLGDYAK
                     QLPLFVFNELFGCTADIGDRVVFGITGMFDGVNAEQAVGVMFGAIGELVALKRAKPGDD
                     VPSWLMEHQARLTDEELVHQIALLLVAGNEPLRNLIGNTLHRLLTHDAYADQGGLIDEA
                     IDDTLWENPPMQNLAPHYPAADMEFAGQKLHAGDLLLVSFAAANTGPALTAARKAGSNR
                     AHLAWSAGPHACPSKEPARQITVTAIENLLNKLPDVELAVPSESLTWRPGPFNRGLTVL
                     PAKFTPVQIAHRPAPTRKEAPLRQEPAATGGRGERGGVWSQFLNWLTR"
     misc_feature    9904..9920
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.51"
                     /tool="antismash"
     misc_feature    complement(9907..9920)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.67"
                     /tool="antismash"
     gene            10001..11326
                     /locus_tag="ASD48_RS12660"
                     /old_locus_tag="ASD48_34620"
     CDS             10001..11326
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358092.1"
                     /locus_tag="ASD48_RS12660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34620"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_063887441.1"
                     /sec_met_domain="indole_PTase (E-value: 1e-129, bitscore:
                     426.2, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTALGPEAPGTTGTAGTPVAPVAPVAQEPETLGAHAARQLLRLGE
                     IAGLSGADSRIYARTLVEALGAVAQRPLDLPPPSRSFLSDDHTPVEFSLSCEQGAAPTL
                     RVLLEPGAGAGDLIENGRTGLRVLREMGRRWGFTTDPLDDLADLFFPSSPEGPLALWCA
                     LELRPGGVPKVKAYLNPAASGEKRAAKTVRKALRRLGHREAFDALPEGDRHLFFALDLG
                     DWAEPRVKVYLAHHDLSAARAYTLSRMDGGPGRTEIEEFFRIVAGPGTDADAVGFGGGG
                     GAGAGAGEGAGGGGEPRPVRRPVQTCHAFTDTGTGLPSGFTLYVPVRDHARHDGESLDR
                     ATALLGHYGIDPAPVLRGSAAVTSRRPEDGVGLVAYLGLAHQRGRPPRVMTYLSSEAYE
                     VRPPTAALPAVPLSVAPAPVSRPVSPPVPSTASLPAAGVTGR"
     cand_cluster    11064..24001
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    11064..24001
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[16063:19001](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(16064..19001)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="2"
     gene            complement(11663..12949)
                     /locus_tag="ASD48_RS12665"
                     /old_locus_tag="ASD48_34625"
     CDS             complement(11663..12949)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FMO-like"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358093.1"
                     /locus_tag="ASD48_RS12665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34625"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_057601826.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.4e-11, bitscore:
                     37.8, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FMO-like (E-value: 4.5e-79, bitscore:
                     259.9, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLCLIGAGLSGLAAAHALKSEGLDFVCLEQASDVGGLWRQPGAG
                     ERGPGYLSLHLNTNKQLTGYADHPMPAGYPVYPRHSQLAAYLRSFAEWAGLLDHIELET
                     TVESVRRAADGSWTVVSRDSQGVCTTRDFSHVIVASGHNTEPVLPAAPPGSETFKGTIL
                     HALDYRDGSDYTGQRVVVVGLGASAVDIAADLSRYAAQTVLSVRRGLHILPKQLFGMPL
                     DDVAEAPWWTDMSLAEQRRFIEQALLVARGKLSDYGLPEPDHPVFASAVTISDEILTRI
                     RHGGVVPKPAIDFVDDGRVVFTDGTSVPADAIVYCTGYRMAHPFLPPDCPVGPQGSVEL
                     YKRVVAPDHPGLHFIGLVRPHGSVTRLVEAQARWVARIVAGKAVLPERDVMRKEISTYL
                     GGVAGQYGQTQGASIQVNVAPYLEELRDE"
     gene            complement(13136..13783)
                     /locus_tag="ASD48_RS12670"
                     /old_locus_tag="ASD48_34630"
     CDS             complement(13136..13783)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007495632.1"
                     /locus_tag="ASD48_RS12670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34630"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_057601664.1"
                     /transl_table=11
                     /translation="MLGGRRSSYRERVADALRAALIAGELLPGEVYSAPALAARFGVSA
                     TPVREAMLDLAKEGLVDAVPNKGFRVTEVSDRQLDEYTHVRALIEIPTVVALATTADPV
                     SLEALRPAAREIVTAAVAGDLIAYVEADTRFHLGLLALAGNAHLVEVVRELRGRARLYG
                     LTALSASGRLLASAEEHLELLDALLSRDERAVRAVMTRHLGHVRGLWASARE"
     gene            13881..14012
                     /locus_tag="ASD48_RS45955"
     CDS             13881..14012
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASD48_RS45955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_282438184.1"
                     /transl_table=11
                     /translation="MTGVTGAPGSPGGADAVGVWLLVRRVAAMVGLLGADCAMSLST"
     gene            complement(14051..15052)
                     /locus_tag="ASD48_RS12675"
                     /old_locus_tag="ASD48_34635"
     CDS             complement(14051..15052)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358096.1"
                     /locus_tag="ASD48_RS12675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34635"
                     /product="proline racemase family protein"
                     /protein_id="WP_057601665.1"
                     /transl_table=11
                     /translation="MRSKLVLHAVDSHTEGMPTRVITGGIGTVPGATMNERRLYFREHR
                     DDVKQLLMNEPRGHSAMSGAILQPSTRPDCDWGVLYIEVSGYLPMCGHGTIGVATVLVE
                     TGMVEVVEPVTTIRLDTPAGPVVAEVTVEHGAATSVTLRNVPSFSVALDRGATLPDGRT
                     VTYDLAYGGNFYAILPLEEFGLPFERARKDDILRAGLSLMEVINSEQEPVHPEDPSIRG
                     CHHVHVYAPGATARHSRHAMAIHPGWFDRSPCGTGTSARMAQLHARGELPLHTEFVNES
                     FIGTRFTGRLLGTTEVAGRPAVLPSFTGRAWITGTAQYLLDPTDPFPAGFVL"
     gene            complement(15093..16025)
                     /locus_tag="ASD48_RS12680"
                     /old_locus_tag="ASD48_34640"
     CDS             complement(15093..16025)
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125678.1"
                     /locus_tag="ASD48_RS12680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34640"
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_057601666.1"
                     /transl_table=11
                     /translation="MPDSTAPASPPAPAASPHRPWRGVLVATALPLRDDLSVDYDRYAE
                     HCAWLVANGCDGVVPNGSLGEYQVLTPEERATVVETAVAAIGGERVMPGVAAYGSAEAR
                     RWTEQAAEAGCSAVMLLPPNAYRADERAVVAHYAEVAAAGLPVVAYNNPIDTKVDLVPE
                     LLARLHGEGHVQGVKEFSGDVRRAYRIAELAPDLDLLIGADDVLLELAVAGARGWVAGY
                     PNALPKSSVELYRAAVAGDLTTALPLYRRLHPLLRWDSRVEFVQAIKLSMDVVGRHGGG
                     CRPPRVPLPPEHEAAVRAATEKAVAAGLA"
     gene            complement(16064..17470)
                     /locus_tag="ASD48_RS12685"
                     /old_locus_tag="ASD48_34645"
     CDS             complement(16064..17470)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058969.1"
                     /locus_tag="ASD48_RS12685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34645"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_057601667.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3e-24, bitscore:
                     79.4, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 7.7e-13, bitscore:
                     42.4, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAHRPVLAVIGAGPAGLAAALAAAARGVRVILIDSAAEAGGQFY
                     RQPARGLGARRPQTLHHQWRTWERLRAGLDAQLAADRVTHLSDRHVWCVEGQSSGFTVH
                     ALIGPEQEESVAVRADGVLLATGGYEKVLPFPGWTLPGVVTAGGAQALLKGGLVLPGRT
                     AVVAGTGPLLLPVATGLAAAGAQVVALLESAGPRDFTRRARTWAGAPAKLAEGAGYAAR
                     LLRHRVVVMVRHAVLEAHGTERLESVTVAALDPEGRPAPGTERRVVCDTLAVGHGLLPH
                     TDLAEGLGCRLDGMGVSVDDEQRTDVPGVWAAGETTGIGGSTLSLAEGHIAGRSAAARL
                     TDTAPDPREWAPAARARTRLRSFFAALDAAYAARPDLWTDRVTDETVVCRCEEVTAGAV
                     REAVGTLGAGDLRTVKLLTRAGMGWCQGRVCEPGVAGVAGCALTPARRWLARPVPLGVL
                     ASPADPPTPQ"
     gene            complement(17467..17823)
                     /locus_tag="ASD48_RS12690"
                     /old_locus_tag="ASD48_34650"
     CDS             complement(17467..17823)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125680.1"
                     /locus_tag="ASD48_RS12690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34650"
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_057601668.1"
                     /sec_met_domain="Fer2_4 (E-value: 3.8e-28, bitscore: 91.2,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPLKLTRARPGAPFTLTFDGREIEALPGQTIAAALWASGVTAWR
                     TTRGEGRARGVFCGIGVCFDCLVTVDGHPGRRACLVAAVPGADIRTQAGTGHEEAGNDA
                     AGHEGPEHEGAGPR"
     gene            complement(17811..19001)
                     /locus_tag="ASD48_RS12695"
                     /old_locus_tag="ASD48_34655"
     CDS             complement(17811..19001)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125681.1"
                     /locus_tag="ASD48_RS12695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34655"
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_057601669.1"
                     /sec_met_domain="DAO (E-value: 1.3e-62, bitscore: 206.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKRPSGDVVVVGAGMVGAACALYAARAGLDVVLVDRGPVAGGTT
                     GAGEGNLLVSDKEPGPELQLALLSTRLWGELAQELGAAVEYEPKGGLVVASTPASLTAL
                     VELAAGQRAAGVSAVEVQPDQLHELEPYLARGLAGGVLYPQDAQVMPTLAAAHLVRASG
                     ARLETGRTVTRVLRDTAGAVRGVRTDRGDILAPAVVNAAGTWGAEIAALAGVRLPVLPR
                     RGFVLVTEPLPRRVRHKVYAADYVADVASDSAALQTSPVVEGTASGPVLIGASRERVGF
                     DRSFSLPVLRALAAGATRLFPFLEQVRAMRTYLGFRPYLPDHLPAVGPDPRVPGLFHAC
                     GHEGAGIGLATGTGHLIAQTLTGRRPELDLTPMRPDRFDRPDRLDRFAEEAAPWIP"
     gene            complement(19080..19874)
                     /locus_tag="ASD48_RS12700"
                     /old_locus_tag="ASD48_34660"
     CDS             complement(19080..19874)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125682.1"
                     /locus_tag="ASD48_RS12700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34660"
                     /product="hypothetical protein"
                     /protein_id="WP_057601670.1"
                     /transl_table=11
                     /translation="MLAVALAVGTLLATAACSDDGDDSASTDSSTATSSAGKQTATASP
                     TITPLTSAGAQTALITEGDLEDNWTQVKTAAGWRNRMLIGTVDAAQFLTGKTQAADCQR
                     LLDGLYDEDLLGAPPGPSALTGFTEGNSRLLYQVAAYRPASLDQSFDWLKTLPTACDQF
                     NAVASDGSTRTVQVVEASLPDSGDARQGLTVTVAGPSGGTPVTLTMDVAVVRVGDDAIT
                     VTNGGSDGADHDSTEDAVSHGTTRLKDVQEGRSPASEPSEFD"
     gene            20333..21037
                     /locus_tag="ASD48_RS12705"
                     /old_locus_tag="ASD48_34665"
     CDS             20333..21037
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125683.1"
                     /locus_tag="ASD48_RS12705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34665"
                     /product="nucleotidyltransferase domain-containing protein"
                     /protein_id="WP_057601671.1"
                     /transl_table=11
                     /translation="MTVTNLLLSGIVGSTAYGLAREGSDIDRLGMFAAPTEELHGLHQP
                     KESHVSTAPDRTLHEAAKWCRLALGGNPTVMELVWLPDELYEVRTPIGDELIDLRVTLL
                     GARRVRDAYLGYAAQQFRRLRNRSEGTLTAETRKRTAKHARHLKRLCTQGYELYATGRL
                     TVRVDDPESYHAFGEQVAADPEAALPLLRDYEEAFDETRSVLPEQPDETAADAWLRRVR
                     RQYYTATRDLPG"
     gene            21493..23691
                     /locus_tag="ASD48_RS12710"
                     /old_locus_tag="ASD48_34670"
     CDS             21493..23691
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020125685.1"
                     /locus_tag="ASD48_RS12710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ASD48_34670"
                     /product="elongation factor G"
                     /protein_id="WP_057601672.1"
                     /transl_table=11
                     /translation="MRNHLDRHLSAVRNLGILAHVDAGKTTVTERILYATGTTHKRGEV
                     HDGTTVTDFDPQERDRGITIFAAAVSCDWDGHRINLIDTPGHVDFADEVERSLRVLDGA
                     VAVFDAVAGVEPQSESVWRQADRHGVPRIAFVNKLDRVGADLDAAVASIRDRLHPVPLV
                     VQLPIGTEDGFTGVVDLLRMRALTWGDGGGTAVEDAVPEDLREEALRRRRLLEEAVAER
                     HPGALEEFCDRETLSAETLSGALRELTRTGDAVVVLCGSAYRNRGIEPLLDAVVAYLPS
                     PSDVPPVCGMPGGAAGMRNTKDGVRDAADGMHSTVHGMHEAADRRRERADRMQDAVGEQ
                     RPADPAAPFAALAFKVAATPTGRLTYLRVYSGTIEKGDAVWESGARRIERIGRILRVQA
                     DRHAQLERAVAGDIVAVIGLKSARAGSTLSAPGAPLVLEPPGVADPVVSVAVEARASTD
                     ADRLVSALARLAEEDPSLVVRTDPETGQTLLSGMGELHLEVAVEKIRRSLGLEVNVGRP
                     RVSYRETVARGVSGLVFRHVKQDGGAGQFAHIVLDVEPLDAETAGGVAETGFTFRSTVV
                     GGRVPQEYVRAVEAGCRDALAEGPVGGHPVTGLRVTLTDGATHVKDSSEMAFRTAGRLG
                     LREALRGCAMVVLEPVVEVTVTVPEDAVGGVLGDLAARRGRVGDSAVRGGSAVVTATVP
                     LAELFGYATRLRSRTQGRGTFSARPTGYAPAPAVATTR"
ORIGIN
        1 gtccggcgac agccgcttgc cgtaccccat ccggaagtcg aagggcgttc cgacgatcac
       61 gatgacgtcg gcgcccgaga aggcgtagcg gcgggagagc tggaagtggt gcgggtcgcc
      121 ggggggcagg gtgccgcggc cggcgccgtt catgtaggcg gggatgttca gggtgcgcac
      181 cagatcgatg gcggcttcgg tgccccgggt cgtccacacc tggctgccca gcaggatcgc
      241 gggcttctcg gcgtgcacga gcaggtcggc gagcttctcg accgcctcgg ggtcgccggc
      301 cgagcgggtc gaggcgcgat aggcgcccgg ccgcggcacg cgggccttcg ccaccggcac
      361 cttggcgtcg aggacatcgc gcgggatctc caggaaggcg ggtccgggcg cgccgtggta
      421 gcactcgcgg aacgccatcg acaccatgtc cgccgcgcgc gccgtgtccg gcaccgctgc
      481 cgcgaacttg gtgatcggcg tcatcatgtc gacgtgcggc aggtcctgga gggagcccat
      541 cttgtgctgg gtgagcgctc cctggccgcc gatcaggagc atcggggact ccgcgcggaa
      601 cgcgttggcg acaccggtga cggcgtcggt ggtaccgggg ccggccgtga cgaccgcgca
      661 gccgggcttg ccggtgatgc gcgcatagcc gtcggcggcg tgggccgcga cctgttcgtg
      721 gcgtacgtcg acgacttcta tgccctcgtc gacgcagccg tcgtagatgt cgatgatgtg
      781 gccgccgcac agggtgtaga tgcggtcgac cccctcggcc ttgagtgcct tggcaacgag
      841 atgaccaccg gagatcacgt cctgggtgtc gtcgggcatg gcgaagtccc gtcccttcgt
      901 aggggggtgg aaggctctcc cggtacattg catacagtcg acgaatactg tatgaagctt
      961 gttatcccgc atccggtggg tggtgtccag ggggcgtgcg gcactttcgg tcatcggagt
     1021 ccggcctcgc gaaggcgggg cggtggactt cggattcgac ttcacagacg ggatccgaga
     1081 tggacctgta cgaacaccag gcaagggaac tcttcgcgga ccacggcatc ctggtccccc
     1141 gggccgaggt caccgactcg cccaaggagg cgcgcgcgat cgctagtcgg ctcggtggac
     1201 gagcagtggt gaaagcccag gtcaagacag gtggccgagg caaggcgggc ggcgtcagga
     1261 tcgccgccga cccggccgcg gccgaactga cggcacgaca gatcctgggc atggacatca
     1321 agggacacac ggtcggttcg gtgatggtgg cccaacccgt cgacgtcgag gcggagttct
     1381 acgtggccta cgtgctggac cgcgtggccg gccgtttcct cgcgatcgcc tccgccgagg
     1441 ggggcacgga gatcgaggag gtcgccgcca cccggcccgc ggcggtcgcc cgcatccctg
     1501 tcgatccggc ggagggcgtc acgtcggcgc aggccggcga gatcgccgcc gcggccggac
     1561 tgcccgcgca gaccgcggac gtcctcgtgc ggctgtggca ggtgctgatc cgggaggatg
     1621 ccctcctcgt cgaggtcaac ccgctcgtcc gcacccggca ggggcagatc ctcgccctcg
     1681 acggcaaggt caccctggac gacaacgcgt tcttccggca gtcacgttgg ggcgcggagg
     1741 ccaccgcgca cggtgacccg ctggaggcgg cggccgctgc caagggcctc aactacgtga
     1801 aactggacgg cgaggtcggc atcatcggca acggcgccgg actcgtcatg tcgaccctcg
     1861 acgtcgtcgc cggctgcggg gcccgcccgg ccgacttcct cgacatcggc ggcggcgcgt
     1921 ccgccgagat catggcggac gggctgtcgg tcgtcctctc cgaccccgcc gtcaagtcgg
     1981 tcttcgtcaa cgtcttcggc ggtatcaccg cgtgcgacgc ggtcgccgaa ggcatcgtgc
     2041 gcgctctgga cacggtacgg ctgaccaagc cgctcgtcgt ccggctcgac gggaacaacg
     2101 cggcccgggg gcgggccatc ctcgacgccc accggcatcc gctcgtccag caggccacca
     2161 ccatggacgg cgccgcccgc cgggccgccg aactcgccac cgcagtctga ggagacgacg
     2221 ccatggccat ctacctcacc aaggagagca gggtcctcgt ccagggcatg accggtgccg
     2281 agggcatgaa gcacacccgg cgcatgctcg cggccggcac caacatcgtc ggcggtgtca
     2341 acccgcgcaa ggcgggccgg gccgtcgact tcgacgaccg tgcggtgccc gtcttcgggt
     2401 cggtcgtcga cggtgtgcag tcgaccggcg ccgatgtcac cgtcgtcttc gtgccgcccg
     2461 ccttcaccaa ggccgccgtc atcgaggcgg ccgacgcggg gatcggcctc accgtcgtca
     2521 tcaccgaggg cgtcccggtc cacgactccg tcgccttcac cacccatgcc gccgcccgcg
     2581 gaacgcgcgt catcggcccc aactgccccg gcctgatcac ccccggccag tgcggcgcgg
     2641 gcatcatccc ggccgacatc accaagccgg gccgcatcgg cctggtctcc aagtccggca
     2701 cgctcaccta ccagctcatg tacgaactgc gggacatcgg cttctcgacc tgcgtcggca
     2761 tcggcggcga cccggtggtc ggcaccagcc acatcgactg cctgaccgcc ttcgaggaag
     2821 accccgacac cgaactcgtc gtcctcatcg gcgagatcgg cggcgacgcg gaggagcgag
     2881 cggccgccca catccgcgcg cacgtcacga aacccgtcgt cggctacatc gccggcttca
     2941 ccgcgcccga gggcaggacc atgggacacg cgggcgcgat cgtctccggc tcctcgggga
     3001 ccgcgcaggc gaagaaggcg gcactggaag cggcgggggt acgggtgggc gccacaccga
     3061 gcgagaccgc ccgtctcgcc ctcaccgtcc tggacgaagg cgcccgacgc cgctgaagcg
     3121 tgccggccgt catcccccgg agccgtgcgc cctgtgtgcg tgctccgtgg ccacgcacaa
     3181 ccgcccccga ccgtgcaccg agagcggagc agccccatgc cgaccaccct caccctcaga
     3241 tccggcacgt cctggcccga cgcctggcgg cggtgcctgg ccgtcgcccc cgaggccttc
     3301 cgcgaggacc gtgtcctcaa cctctggaac gcgtcctggc aggccgacgg ccggacgctg
     3361 ccggccacca gcccggtcga cggcaccccc atcgcgggtc cgccgcgact ggacggggac
     3421 accgcccggc aagccgtccg cgccggtctg gatcagcacc gcgcctggcg gcacgtcccg
     3481 ctggaggagc ggcgcgcccg catcgcggcc accctcgacg ccctcgccga acaccgcgaa
     3541 ctcctcgccc tgctcctggt ctgggagata ggcaaaccgt ggcggctcgc gcgggccgat
     3601 gtcgaccggg ccgtcgacgg cgtgcggtgg tacgtcgacg gcatcgaacc catgctggac
     3661 gggcgggccc cgctggacgg cccggtgtcc aacatcgcga gctggaacta cccgatgagc
     3721 gtgctcgtcc acgccatgct ggtccaggcg ctggcgggca acgcggtcat cgccaagacg
     3781 ccgaccgacg gcggtgtcgc ctgtctgacg ctggcctgtg cgctcgccgc acgcgagggc
     3841 gtcccggtca ccctcgtcag cggcagcggc ggcgagctgt cccgggcgct ggtccgggcg
     3901 cccgagatcg gctgtgtctc cttcgtcggc ggccgcgaca ccggtgccgc ggtggccacg
     3961 gccgtcgccg acctcggcaa gcgacacgta ctcgaacagg aaggactcaa cacctggggc
     4021 atctggaact actcggactg ggacgccctc tccgcggtcg tgcccaagct cttcgactac
     4081 ggcaaacaac ggtgcacggc gtatccgcgc ttcgtcgtcc agcgaaccct gttcgacgag
     4141 ttcctggcgg cctacctccc ggcggtgcgc acgctgaccc tcgggcaccc gctggccgtg
     4201 gagaagcgcg acgatccgta tccccggctg gacttcggac cggtgatcaa cgcggccaag
     4261 gccaaggaac tgcacgacca gatcgccgag gccatcgacc ggggcgcggt cccgctgcac
     4321 cgcggccggc cggccgacgc ccgcttcctg cccggccagg acacctcggc ctacgtccag
     4381 cccgtcacgc tcctcgggcc accgccgtcc tctccgctgc accacgcgga gccgttcggc
     4441 ccggtcgaca ccatcgtcct ggtcgacacg gaggcggagc tgctggccgc catgaacgcg
     4501 tccaacggcg cactcgtcgc caccctgtcc acggacgacc ggagcaccta cgaacggctg
     4561 gctccgcaga tccgcgcgtt caaggtcggg cacggcacgg cccgctcccg gggcgaccgc
     4621 gacgagctct tcggcgggtt cggcgcgtcc tggcgaggcg ccttcgtcgg cggggagctg
     4681 ctggtgcgcg cggtgacaca ggggccgacg ggggagaggc tgcccgggaa cttcccggac
     4741 taccagctga tgccctgacc acacggcggc cggacgacca gacggccgga cgaccagacg
     4801 gccggacgac agacggccgg acggccggac ggccggacga ggctgcgacg gctcctcggc
     4861 cggcggtccg gccggcaggc ttcggccgcc aggcttcggc accgacggtg gcccggccca
     4921 acccggtcga actcagtcgc cgtcctggtc gtgctcgccg aagaaggaac gttgtcgctg
     4981 gccggggcgg ccgggcggct cggcgtcgat cgcaccaccg tggcggcgct cgtcgacggt
     5041 ctggaggacc acggtctggt ggaacggcgg cgcagccctc gagaccgccg ccggaacacc
     5101 gtccggctca cggccgccgg cctggtctgc ccggagcggg gcgaggggcg cgccgggccg
     5161 cggagcgccg gttccccgcc ccgctggtcg agcaggcggc ggccgcgctg ctgcgggcgc
     5221 cgcggaggct cgtcgtcgag gagccgacgg tgaggtgacc gcccggtcac ccggtgtgag
     5281 gtgcccgtac ggccgtcccg tcacccgtgc ggccagcgga tatgcaggtg agacccactc
     5341 cgaaaccttg gtattgttgt gcctgtcgcc gcggggagaa ctcacgcagc ggcaacacct
     5401 ggtccgggtg gcggaatggc agacgcgcta gcttgaggtg ctagtgccct ttatcgggcg
     5461 tgggggttca agtcccccct cggacactct cactctccgt atcgaacggc ttccgttcgg
     5521 tgaacggtca attacccgca ttcggcgtat cgccgggtgc gggttttgtt gtttccgtat
     5581 cccttgcctc cggaatgtcg cggaagcccg tttatcggtt gtcctgtcgg gctgtgtgtc
     5641 cgctcgctcg acggggacgc ttcccggtca ctccgccgtt gctcgcaggt cccgctgacg
     5701 atccgtcaat gttcacctcc gtacgcctat tgacggtctg tgactccatc ttgtggtgat
     5761 acgatcacgc tcgcttgtag agcgggcgga tgggtgcaag acgacatctc cgactacggg
     5821 gacagtccgg gcggtcaccc gtcattgcgg gcggtccgcc ggtccacccg cgttgacggg
     5881 aattcagcaa ctggccgtca gtcgcctgaa gagagtctta tgacgcatta catacagaac
     5941 ccggtactct gggctctcct cgtggccgta ctcgccgccg tcgccctcat cgttcgccag
     6001 cgcagggcgg cgcgtgtctt gaggcaggag atcgcggggc tcaggtctca ctactccgcg
     6061 ttggaaaacg agtacgcgca atccgtcgag gcagctcagg aacaagccga agaggctacg
     6121 aaaacggtcc tcaagtccgc gatgcggacc cttcagggcc ttgccgcgga acagcagttg
     6181 attgtttccc ggctgcagaa caaatacggc gagtcggtta tcctccagga ccttctggag
     6241 atcgaccaca cgaactcgca gttcggccgt cgagcccagt ccatcgcggt tctctgcgac
     6301 ggctggctgg ggcgcgcacg tgatgtcgcc tccgtgtacg acgtggtacg cagcgcgcag
     6361 ggcagggttc gccactaccg gcgggtggaa atcctctcgc aggtcgactt cggcatcacg
     6421 agccgtgcgg tcgaaccggt cgccctggcc ctcgccgaac tgctcgacaa cgcgacgagc
     6481 tattccagcc cggacaccgt cgtcgaaatc aacattcgta ccgtgcccaa gggtatttgt
     6541 atcgtcgtcg acgatgcggg tgtcggtatg aacgacgaag agcgcgcccg tgccgacaaa
     6601 ctcctgtcga gcgagcgggt ctccggtgtt tccgcactcg gcaacccgcc gcagttcggt
     6661 ttcgcggtga tcggtgtgct cagcgagcgc ttcggcttcg aggtgtcggt ggactccacc
     6721 tccccctacg gaggcgtccg ggcggtcctg ctcctgccgc acgacctgct caccaacgcg
     6781 cccgagcaga aggagccggc tccggtcgtt cccaccgtcg ccgccacggc ccgcagcggt
     6841 cccgaaggcg ggctctccac cagcaccacc gccgacggcc tgccgaagcg gcgtcgcaag
     6901 cggcccatgg ccatcgtgcc cggcagcgcg tccgcgtcca ctcccgcccg ttcgggcgcc
     6961 gagacggcgg cgatcatggg tgccttccag cggggaaccc agtcgggccg ggccacgcct
     7021 gcgagtcccg cggaaaagtc gagcagcacc cgtggtgctg gcagcgaagg gcatgaggtc
     7081 tcgtgaacga cgatctgtca tggatgcttg acagcgcctt ggagataccc ggggccctgc
     7141 acgcagtcct catctccgcg gacggcctgc tgatggcacg gacgcaggac ttcgacaagg
     7201 acgacgcgga ccgggtggcc gccgcgatga gcggggtgca gtcgctcagc cgctcgctgg
     7261 cgttcttctg cgaggacccg cagatggggt ggcggcagac gctggtcgag ttcgacgggg
     7321 gctgggtctt cctgatctcc gccggtgagg gggcctacct cggcgtctcc gcctcgccgg
     7381 acgtcgacat ggcggacatc accttccgga tgcagcaact cgtcggccag ctcggcaagg
     7441 cgctgacgac accgccgcgc gagaacctcg gcgtgcggtc atgaagggct tcgacgaact
     7501 ggagccgcag acgccggagt tagtgcgtcc gtacgtcatc accaagggac gtgggctgcc
     7561 cgacgagggg cagctctccc tcatcaccct ggtcacggcg gccgccgatc acgagcagcg
     7621 gccgacccgg ctgtcccccg aggaacagaa cctgttggac ctgtgctcgg ccggctacct
     7681 gtcggtcgcc gagatcgccg ggcacaccca actacccctg ggcgtggtga agatcctcct
     7741 cgccgccctc accgaaggcg gctacctcat cacgcgcccg ccggtacagc gggctccgct
     7801 cgccgaccgg gacatcctgg aggaggtgct gaatggtctc agggccaagt ttggatgagc
     7861 aggcctacgt ccgtgacggg gcgacgcaga cggcggtgaa gatcctcgtc gtgggtcact
     7921 tcgcggtcgg caagaccacg ttcatcggag cgatctccga gatccagccg ctgaccaccg
     7981 aggagacgat gacgcgggca gccgagtcgg tcgacgacct caagggagtc cagggcaaga
     8041 ccaccaccac ggtcgccatg gacttcggtc gtctgaccat cagcgaccgt gtcgtgctgt
     8101 atctgttcgg aacgccgggc cagcagcgtt tcgtgcagat gtgggaggac atggcacgcg
     8161 gcgccctcgg cgcgctggtg ctcgtggatc ccgagcggct cgcggactcg ttcgccgtga
     8221 tcgacctgat cgagcagtac ggactcgact acgccatcgc cgtcaaccac ttcgacggcg
     8281 ccccactgcg ggacgagacg gctctgcgcg acgcactgga cctcctcgac gacacccccg
     8341 tcgtcacctg cgacgcgcgg gacgagcggt cgtcggccga cgcgctgatc accctcgtcc
     8401 gccacctcca ggaccgcgca cactaggagc agacatggac caacccaccg cacccgtgcc
     8461 cccgcccggg tgcccggcgc atcaggccgg cggcagagtg cccctgcacg ggctggagtt
     8521 cgccgccgac ccgcaggcct actacagcta cctgcgccac ttcgggccga ccgcgccggt
     8581 cgaactcgct ccgggtgtcg aggcgaccct catcacggac tacgccgtcg cactccaact
     8641 gctgcaggac tcaggcgcgt tccgcaagga cgcgcgccgc tggcgtgacc tcaacgaagg
     8701 acgggtcccc ccggacagcc cggtcgcgcc cctgctgtcc taccggccca acgccatgtt
     8761 cagtgacggc gccgagcacc tgaggctccg ccaggcgatc acggacagca tggcgcgcgt
     8821 cgacacgcgc aagctcagcc ggaccacgga gcaggtctcc aactacctga tctcgcagtt
     8881 cggttcgcgc ggctcggccg acctgctcgg cgactacgcc aagcagttgc cgctcttcgt
     8941 gttcaacgag ctgttcggct gcaccgccga catcggtgac cgcgtcgtgt tcggcatcac
     9001 cggcatgttc gacggtgtga acgccgagca ggcggtcggg gtcatgttcg gcgccatcgg
     9061 cgaactggtg gcgctcaagc gtgccaagcc gggcgacgac gtgccctcct ggctgatgga
     9121 gcaccaggcc aggctcaccg acgaggagct ggtccaccag atcgcgctcc tgctggtggc
     9181 cggcaacgag cccctgcgca acctcatcgg caacaccctg caccggctgc tcacccacga
     9241 cgcgtacgcc gaccagggcg gtctgatcga cgaggcgatc gacgacacgc tgtgggagaa
     9301 cccgcccatg cagaacctcg cgccgcacta cccggcggcc gacatggagt tcgcgggcca
     9361 gaagctgcac gccggcgacc tgctcctggt cagcttcgcc gcggccaaca ccggcccggc
     9421 actgacggcg gcccgcaagg cgggcagcaa ccgcgcccac ctggcgtgga gcgcgggccc
     9481 gcacgcctgc ccgtccaagg agccggcccg gcagatcacc gtgacggcca tcgagaacct
     9541 gctcaacaag cttccggacg tcgaactcgc cgtaccgtcg gagagcctga cctggcggcc
     9601 gggtcccttc aaccggggtc tcaccgtgct gcccgccaag ttcaccccgg tgcagatcgc
     9661 gcacaggccc gccccgacgc gcaaggaagc gcctctgcgc caggagccgg ccgcgacggg
     9721 tggcaggggt gaacgcgggg gtgtgtggag ccagttcctc aactggctga cgaggtgatt
     9781 cacgcaacac ccgtcaactc ttcaccatcg catgacgatt caacctcagg ggtagtgagg
     9841 aacgcggcat tccatgttgc tcacacacca gaggaggtgt cgtggaccac atatccaccg
     9901 acgccgtttt catacaacat ccgccccttg tgcaccccct gatacccgcc ccgcaaggcg
     9961 ggtatcttct tgcgcccctc ctcccccgag gagaggcccg atgactgccc tcggtcccga
    10021 agctccgggc accacgggca ctgcgggcac tccggtcgct ccggtcgctc cggtcgctca
    10081 ggaaccggag acgctcggcg ctcacgcggc acgtcagctg ctgaggctgg gtgagatcgc
    10141 ggggttgtcc ggagccgact ccagaatcta cgcgcgaaca ctcgtcgagg ccctgggtgc
    10201 cgtcgcgcaa cggcccctgg acctgccgcc gcccagccgc agcttcctct ccgacgacca
    10261 caccccggtg gagttctccc tctcctgcga acagggcgcg gcgccgacgc tgcgcgtact
    10321 gctggagccg ggagccggtg ccggcgacct gatcgagaac ggccgcaccg gcctgcgggt
    10381 gctgcgcgag atggggcggc ggtggggatt caccaccgac ccgctcgacg atctcgccga
    10441 cctgttcttc ccgtcctcgc ccgaagggcc cctggcgctg tggtgcgcgc tggagctgcg
    10501 tcccggtgga gtccccaagg tcaaggccta tctgaacccc gcggcatccg gggagaagcg
    10561 cgccgccaag accgtaagga aggcgctgag acgactcggg caccgggagg cgttcgacgc
    10621 actgcccgaa ggcgaccgcc acctgttctt cgccctggac ctgggtgact gggcggagcc
    10681 acgggtcaag gtctacctcg cccaccacga cctgtcggcc gcgcgggcgt acacgctgtc
    10741 ccgcatggac ggcggacccg gccgtacgga gatcgaggag ttcttccgca tcgtggccgg
    10801 gcccggcacc gatgccgacg ccgtcggctt cggaggcgga ggcggagcgg gcgccggagc
    10861 cggggagggg gccgggggag gaggggaacc gcggcccgtt cgccggcccg tccagacctg
    10921 ccatgccttc accgacacgg ggaccggcct gccgagcgga ttcaccctct atgtcccggt
    10981 gcgggaccac gcgcggcacg acggtgagtc cctggaccgg gcgacggcgc tgctcggcca
    11041 ctacgggatc gacccggcac cggtgctgcg cggctcggcg gccgtcacct cgcggcggcc
    11101 ggaggacggt gtgggactgg tcgcctacct gggcctggca catcagcggg gacgtccgcc
    11161 ccgggtcatg acctatctct cctcggaggc gtacgaggtc cggccgccga cggccgcgct
    11221 cccggccgtg ccgctgtccg tcgccccggc ccctgtctct cgtcctgtct cgccccctgt
    11281 cccgtccacc gcctctctgc ccgccgcggg cgtgaccgga cggtaggtgc cgcggaaccc
    11341 gcggatcggt gccgtccacg gtgtgccgag gacccgtggt gcagctccct gcagtacacc
    11401 tcctgcagta cacctcctgt agaacagctc ctgtggaaca gttcccgtag ccaccggccc
    11461 gcgtggaaca gcggcaccag cacaacctgc ggtacaacag caccgcggaa cagcacctcg
    11521 gggggagccg tgcgccgacg ctgtcgaacc gctcccctcg tcccacgaga agtgcacacg
    11581 tgagccgccc agaccgcccg ggcggcctcc cgacgcgggg catcgaatcc gatgcccgcc
    11641 tcccgccttc accgacggtc cgtcactcgt cgcgcagttc ctccaggtag ggcgccacat
    11701 tgacctggat cgacgcgccc tgcgtctggc cgtactggcc ggcgacgccc cccagatatg
    11761 tgctgatctc cttgcgcatg acgtcccgct ccggcaggac cgccttgccg gcgacgatcc
    11821 gggcgaccca gcgtgcctgg gcctcgacga gccgggtgac ggagccgtgc gggcgtacca
    11881 gaccgatgaa gtgcaggccg ggatggtcgg gcgcgaccac ccgcttgtac agctcgaccg
    11941 aaccctgtgg accgaccggg cagtccggcg gcaggaaggg atgggccatc cggtacccgg
    12001 tgcagtagac gatcgcgtcg gcgggcacgg acgtgccgtc ggtgaagacc acccggccgt
    12061 cgtcgacgaa gtcgatcgcc ggcttgggaa cgaccccgcc gtgacgtatg cgggtgagga
    12121 tctcgtcgga gatggtcacg gcggaggcga acaccgggtg gtccggctcg ggcaggccgt
    12181 agtccgagag cttgccgcgg gcgacgagca gggcctgctc gatgaaccgg cgctgctccg
    12241 ccagggacat gtccgtccac cacggggcct cggcgacgtc gtccaagggc atgccgaaga
    12301 gctgcttggg caggatgtgc aggcctcggc gcacggagag cacggtctgc gcggcgtacc
    12361 gggagaggtc ggcggcgatg tccaccgccg aggccccgag tcccacgacg acgacccgct
    12421 gtcccgtgta gtcgctgccg tcgcggtagt ccaatgcgtg gagaatcgtt cctttgaagg
    12481 tctcggaccc cggcggggcg gcgggcagga ccggctcggt gttgtgcccc gacgcgacga
    12541 tcacgtggct gaagtcccgt gtggtgcaca cgccttggga gtcccggctg acgaccgtcc
    12601 aggaaccgtc ggccgcccgg cgcaccgact cgacggtcgt ctccagctcg atgtggtcca
    12661 gcaggccggc ccactcggcg aacgagcgca ggtaggcggc gagttggctg tgccgcgggt
    12721 agacgggata tccggccggc atgggatggt ccgcgtaacc ggtcagctgc ttgttggtgt
    12781 tgaggtgaag cgacagatag ccgggaccgc gttcaccggc cccgggctgc cgccagagcc
    12841 cgccgacgtc ggacgcctgc tcgaggcaga cgaagtcgag accctcggac ttgagggcgt
    12901 gtgccgcggc caacccggac agacccgcac cgatcagaca caggctcaca cgttccccca
    12961 cggaatcgac accatccttt cgcacgggca agtgaatgcc cgttcggcac tccctccacg
    13021 cgccgcacgc cagcgacaag gatcacaggc gggatcccgg ggccgaggtg gcgcgaggag
    13081 gggggacggg tagaggggac gtcgtggggc gagccgccca ctccggggcg agtcgctact
    13141 cgcgagcgga ggcccacagc ccccgcacat gccccagatg gcgcgtcatg accgcgcgca
    13201 cggcccgttc gtcgcgggac agcagggcgt ccagcaactc caggtgctct tcggcggagg
    13261 cgagcagacg gcccgaggcg gagagggcgg tcaggccgta caggcgcgcc cggccgcgca
    13321 gttcgcggac gacctcgacg agatgggcat tgccggccag ggcgagcagg cccaggtgga
    13381 accgggtgtc ggcctcgacg taggcgatga ggtcgcccgc caccgccgcg gtgacgatct
    13441 cccgggcggc cggccgcagc gcctcgaggg acaccgggtc ggcggtcgtc gccagcgcca
    13501 ccaccgtggg gatctcgatg agcgcgcgga cgtgggtgta ctcgtccaac tgccggtcgg
    13561 agacctcggt gacccggaac cccttgttcg ggacggcatc gaccaggcct tccttcgcca
    13621 ggtcgagcat cgcctcgcgc acgggtgtcg ccgagacgcc gaaccgggcg gccagggccg
    13681 gcgccgagta cacctcgccg ggcagcagtt cacccgcgat cagcgccgcc cgcagggcat
    13741 cggcgacccg ctcgcggtag ctgctccgcc gaccgccgag cacggggagg gtgggcgcgg
    13801 atgccgatgc ggatgcggat gtggatgtgg aggcggtcgc cgaagcgggg gccggtgccg
    13861 gtgcggatgg tggtgcttgg gtgacgggtg tgacgggtgc gccgggttcg cccggtgggg
    13921 cggacgcggt gggtgtctgg ctgctggtgc gccgggtggc ggccatggtg ggtctcctcg
    13981 gtgcggactg tgccatgtca ctctcgacct gagcactgtg ccatgtcatg tctcaccgct
    14041 gcctgcggtg tcagagcacg aagcccgccg ggaacgggtc cgtcgggtcc agaaggtact
    14101 gggccgtccc cgtgatccag gcacggccgg tgaaactggg cagcaccgcc gggcggccgg
    14161 ctacttccgt cgtgccgagg agccggcccg tgaaacgggt gccgatgaac gactcgttga
    14221 cgaattcggt gtgcaacggc agttcgcccc gggcgtgcag ctgtgccatg cgggcgctcg
    14281 tccccgtgcc gcagggcgag cggtcgaacc agccggggtg gatggccatc gcgtgccggg
    14341 aatgacgggc ggtcgcaccg ggcgcgtaca cgtggacgtg gtgacagccg cggatggagg
    14401 ggtcttcggg gtgcaccggc tcctgctcgg agttgatcac ctccatgagg gacaggccgg
    14461 cgcgcaggat gtcgtccttg cgcgcccgct cgaagggcag cccgaactcc tccagcggca
    14521 ggatcgcgta gaagttgccg ccgtacgcca ggtcgtacgt cacggtacgg ccgtcgggca
    14581 gcgtcgcgcc gcggtccagc gcgacgctga aggaggggac gttccgcaag gtcacggacg
    14641 tggccgcgcc gtgctcgacc gtcacctcgg cgacgacggg cccggccggg gtgtccaggc
    14701 ggatggtggt gaccggttcg acgacctcga ccatgcccgt ctcgacgagc accgtcgcca
    14761 ccccgatcgt gccgtgcccg cacatcggca gatagcccga gacctcgatg taaaggactc
    14821 cccagtcgca gtccggccgg gtggacggct ggaggatcgc accgctcatg gcggagtgcc
    14881 cacgcggctc gttcatcagc aactgtttca cgtcgtcgcg gtgttcgcgg aaatagagcc
    14941 gccgctcgtt catcgtcgcg ccggggacgg tgccgatccc cccggtgatc acccgggtgg
    15001 gcatgccctc ggtgtgcgag tcgacggcgt gcaggacgag cttgctgcgc acgaagtccc
    15061 cttgtctctt tcgaggttga acggctcggt catcacgcca gaccggccgc gacggccttc
    15121 tcggtcgccg cgcggacggc cgcttcgtgc tccggcggca gcgggacccg tggtgggcgg
    15181 cagcccccgc cgtggcgccc caccacgtcc atcgagagtt tgatcgcctg gacgaactcc
    15241 acccgcgagt cccagcgcag cagcgggtgg agccgacggt agagggggag cgcggtggtg
    15301 aggtcaccgg cgacggccgc ccggtacagc tccaccgagg acttcggcag tgcgttcggg
    15361 taaccggcca cccagcccct ggcgcccgcc acggccagtt ccagcagtac atcgtcggcg
    15421 ccgatcaaca ggtccaggtc cggagcgagt tcggcgatcc ggtaggcgcg gcggacgtcg
    15481 cccgagaact ccttgacgcc ttgcacgtga ccctcgccgt gcagccgcgc cagcaactcg
    15541 gggacgaggt cgaccttggt gtcgatcggg ttgttgtacg ccacgaccgg caggcccgcc
    15601 gcggcgacct ccgcgtagtg ggccacgacg gcacgctcgt cggcgcggta ggcgttgggc
    15661 gggagcagca tcaccgccga gcagcccgcc tcggccgcct gctcggtcca acggcgggcc
    15721 tccgccgagc cgtaggcggc gacgccgggc atcacccgct ccccgccgat cgcggccacc
    15781 gcggtttcca ccaccgtggc gcgttcctcg ggcgtgagca cctggtactc gcccagggag
    15841 ccgttgggca cgacgccgtc acagccgttc gccacgagcc aggcgcagtg ctcggcgtac
    15901 cggtcgtagt cgacggagag gtcgtcgcgg agcgggagcg cggtggcgac gaggacgcca
    15961 cgccaggggc ggtgagggga ggcggcggga gcggggggag aggcgggggc ggtcgagtcg
    16021 ggcatacggt gagtcatccc ttccgaatgt gccgtgtgac atatcactga ggtgtcgggg
    16081 gatcggccgg agaagccagc acgcccaggg gcacggggcg ggccagccat cgtcgtgccg
    16141 gagtgagcgc gcagccggcg acgccggcca ctccgggctc gcacacgcgg ccctggcacc
    16201 agcccatgcc ggcccgggtc agcagtttca cggtgcgcag gtcgcccgcg ccgagcgtgc
    16261 cgacggcctc gcggacggcg ccggcggtga cctcctcgca gcggcacacg accgtctcgt
    16321 ccgtgacccg gtccgtccac agatcgggcc gggcggcgta ggcggcgtcc agtgccgcga
    16381 agaacgaccg cagcctggtg cgggcccgcg cggcgggggc ccactcccgc gggtcggggg
    16441 ccgtgtccgt cagcctggcc gccgccgacc gtccggcgat gtgcccctcg gcgagcgaca
    16501 gcgtcgagcc gccgatcccc gtggtctcgc cggcggccca gacgccgggg acgtcggtgc
    16561 gctgttcgtc gtcgacgctc acacccattc cgtcgagccg acagccgagc ccttccgcga
    16621 ggtcggtgtg cggcagcaga ccgtggccca ccgcgagggt gtcgcagacg actcgtcgtt
    16681 ccgtgccggg cgccggccgg ccttccgggt ccagcgcggc gacggtgacg gactcgagcc
    16741 gttcggtccc gtgcgcctcc agcaccgcat gacggaccat caccaccacg cgatgacgca
    16801 ggagtcgggc cgcgtacccg gctccctccg ccagcttcgc gggagcaccg gcccaggtcc
    16861 gcgcccgacg tgtgaaatcc ctgggtccgg ccgactccag cagggcgacg acctgagcgc
    16921 ccgcagccgc gagaccggtg gcgacgggaa gcagcagggg ccccgtgccg gccacgaccg
    16981 cggtacggcc gggcagtacg agcccgccct tcagcagcgc ctgggcgccg cccgcggtga
    17041 ccacgccggg cagtgtccag ccggggaacg gaaggacctt ctcgtatccg ccggtcgcca
    17101 gcagcacccc gtcggcacgg accgctacgg actcctcctg ctccggaccg atcagcgcgt
    17161 gcacggtgaa cccactcgac tgtccctcca cgcaccacac atgacggtca ctcaggtgcg
    17221 tgacgcggtc ggcggcgagc tgggcgtcga gcccggcgcg cagtcgctcc caggtgcgcc
    17281 actggtgatg cagggtctgt gggcgtcgcg cgccgaggcc ccgggcgggc tgccggtaga
    17341 actgtccgcc cgcctcggcg gcggagtcga tcaggatcac gcgcacgccg cgggccgcgg
    17401 ctgccagggc ggcggcgaga ccggccgggc ccgcgccgat caccgccagt accgggcgat
    17461 gtgcggtcat cgtggccccg ccccctcgtg ctccggccct tcgtgacccg ctgcgtcgtt
    17521 tccggcttcc tcgtggcccg tccccgcctg cgtgcggatg tccgcgcccg gcaccgccgc
    17581 caccaggcag gcccgtcggc cggggtggcc gtcgacggtc accagacagt cgaagcacac
    17641 gccgatcccg cagaaaaccc cgcgcgcgcg tccctcgccc ctggtggtcc gccaggccgt
    17701 tacgccggac gcccacagag cggcggcgat cgtctgaccg ggcagcgcct cgatctcccg
    17761 gccgtcgaag gtcagagtga acggggcgcc gggacgggcg cgggtcagct tcaggggatc
    17821 catggcgcgg cctcctcggc gaagcggtca aggcggtcgg gacggtcgaa gcggtcgggg
    17881 cgcatcggtg tcaggtccag ctcaggccgt cgtccggtga gcgtctgcgc gatgaggtgg
    17941 ccggtgccgg tggcgagccc gatgcccgcc ccctcgtgcc cgcaggcgtg gaagagcccg
    18001 ggcacacggg ggtcgggccc gacggcgggc agatggtcgg gcaggtaggg gcggaagccg
    18061 aggtaggtgc gcatcgcccg tacctgttcc aggaacggga acaggcgtgt cgcgcccgcc
    18121 gccagggcgc ggaggaccgg cagcgagaag gaccggtcga aaccgacccg ttcacggctc
    18181 gcgccgatga gcacgggccc ggaggcggtc ccctcgacga ccggtgaggt ctgcagggcg
    18241 gcggagtcgc tcgccacgtc ggccacatag tcggcggcgt acaccttgtg ccgtacccgg
    18301 cgcggcagcg gctcggtgac caggacgaag ccgcggcggg ggagtacggg cagccggacc
    18361 ccggccagcg cggcgatctc ggccccccag gtcccggccg cgttcaccac ggccggcgcc
    18421 aggatgtcgc cccggtcggt ccgtacgccc cgtacggcac cggcggtgtc gcgcagtacc
    18481 cgtgtcaccg tgcgacccgt ctccagacgt gcgcccgagg cccgtacgag gtgggccgcg
    18541 gccagggtgg gcatcacctg ggcgtcctgc gggtagagca caccgcccgc gagaccccgc
    18601 gccaagtacg gctccagctc gtggagttgg tccggctgta cctcaaccgc cgacaccccg
    18661 gcagcacgct gaccggccgc cagctccacc agggccgtga gggacgcggg cgtggaggcc
    18721 acgacgagac cgcccttggg ctcgtactcg acggccgcgc ccagctcctg cgccagctcg
    18781 ccccacaacc gggtcgacaa cagggccagt tggagctcgg gtccgggctc cttgtcggac
    18841 acgaggagat tgccctcgcc cgcgccggtc gtgccgccgg ccaccggacc ccggtcgacc
    18901 aggaccacgt ccagtccggc acgggccgcg tacagcgcgc aggcggcacc caccatgccg
    18961 gcgccgacga ccacgacgtc accactcggt cgcttggtca ccgcagtaat atgtcacatg
    19021 gtgcagaggc ggggaagaag gccggagcgg cgaggacgcg ctcggccgaa ccgccgggtt
    19081 cagtcgaact cgctgggctc cgacgccggt gaacggcctt cctgaacgtc cttgagccgt
    19141 gtggtgccat gactgacggc gtcctcggtg ctgtcgtggt ccgctccgtc ggaaccgccg
    19201 ttggtgaccg tgatcgcgtc gtccccgacc cggacgacgg cgacatccat ggtgagggtg
    19261 accggagtgc cgccggaggg gcccgccacc gtcacggtca gaccctgccg ggcgtcgccg
    19321 gagtcgggca gggaggcctc gacgacctgc acggtgcggg tggagccgtc ggaggcgacc
    19381 gcgttgaact ggtcgcacgc ggtcggcagg gtcttgagcc agtcgaacga ctggtccagg
    19441 ctcgccggtc ggtaggcggc cacctggtag agcagccggg agtttccctc ggtgaatccc
    19501 gtgagcgccg acgggccggg cggggctccc aggaggtctt cgtcgtagag cccgtcgagc
    19561 aggcgctggc agtcggccgc ctgcgtcttg ccggtgagga actgcgcggc gtcgaccgtg
    19621 ccgatgagca tccggttccg ccagccggca gcggtcttca cctgcgtcca gttgtcctcg
    19681 aggtctccct cggtgatcag cgccgtctgc gcgccggccg aggtgagcgg tgtgatcgtg
    19741 ggggacgcgg tggcggtctg cttgccggcg gacgaggtcg cggtgctcga gtcggtcgac
    19801 gcgctgtcgt ccccgtcgtc ggagcaggcc gccgtggcca gcagcgttcc gacggccagg
    19861 gcgacggcca gcacacggac cggacgaccg ggacgcgtcg gcccggccgg accgggcggc
    19921 ccggcgggac ggggtggggt ggacgggcgg gacgacaggc gagggctggt cacgaatacc
    19981 tcctgcggat cggggacggg gcggggcggg gccggtcccc gcgtgggcgc gccccgggcg
    20041 ggttccccaa gggattcctc tcgtcgacct gggcgcttct cgggcaccct gtgggctctt
    20101 gtggtgctgc ctctgcccct acacggcacc accggccggg ccgctcgacc agcgcactga
    20161 tccgtacggg tgaagcgacc gacgggacgg gtcacccacc cggacacggg cggagcgggc
    20221 cgtccggccg gaaaatacga ggtgggcccg gccgcagccg gggcatcatg gcggttctgc
    20281 cgcccggcca cggggacagg cgatcatcac cagggaacga ccgggggctc ctgtgaccgt
    20341 caccaacctc ctgctgtccg gaatcgtcgg ctcgaccgcc tacgggctcg cccgcgaagg
    20401 ctccgacatc gaccgcctcg gcatgttcgc cgcccccacc gaggagctgc acggcctgca
    20461 ccagccgaag gagtcgcacg tcagcacggc gcccgaccgc accctgcacg aggccgcgaa
    20521 atggtgccga ctcgccctcg gcggcaaccc gaccgtgatg gaactcgtct ggctgcccga
    20581 cgagttgtac gaggtgcgca cccccatcgg tgacgaactc atcgacctgc gtgtgacgtt
    20641 gctcggcgcc cgccgggtcc gggacgccta tctcgggtac gccgcccagc agttccggag
    20701 actgcggaac cgcagcgaag gcaccctcac cgcggagacc cgcaaacgga ccgccaagca
    20761 cgcccgtcac ctcaagcgcc tgtgcaccca gggctacgag ctgtatgcca ccggccggtt
    20821 gacggtccga gtcgacgatc ccgagagcta ccacgcgttc ggtgagcagg tcgcggccga
    20881 tccggaagcc gcgctgccgc tgctgcgcga ctacgaggag gcgttcgacg agacccgcag
    20941 cgtgctgccc gaacagcccg acgagacggc cgccgacgcg tggctgcgac gggtgcggag
    21001 gcagtactac acggcgacgc gggacctgcc cgggtgaccg gctgacgcgc tcctcatgcc
    21061 cgcagacgga gacggagacg gaggcggagg tggaggtgga gccggggcgg cgcgacagcg
    21121 ggacgggggt gataaatcac gtgcggcgcg cacccgttca gccctacact ccccagaacc
    21181 gagcgcggcc cacgacacgg gcggcgcggt accgagacga acgaggggag cccggccatg
    21241 cgtgaccaca ccgctgtcgt cgctccccgc tcccgctacg aggtgatcct cgtgtcttcg
    21301 tccgtccggt gctcgctgcg cggccggcac cggatgtcct gacgaacgtc tgagttcgac
    21361 aacgcgctgc tgatgtgccg tatctgacgg cacatcagcg tacgcgcgca tcagcacgtc
    21421 ctcacgtgtc ccgacgtacg tccggaaaat cgcgctgccc gttctcggaa tcaccccgaa
    21481 aggccaaggg ccgtgcgcaa ccacctcgac cgtcacctct ccgctgtgcg caacctgggc
    21541 atcctcgccc acgtcgacgc cggcaagacc accgtcacgg agcggatcct gtatgccacc
    21601 gggaccacgc acaagcgcgg cgaggtccat gacggcacga ccgtcaccga cttcgatccc
    21661 caggagcgcg accgcggcat caccatcttc gccgcggccg tcagctgcga ctgggacggt
    21721 caccgcatca acctgatcga cacccccggg cacgtcgact tcgccgacga ggtggagcga
    21781 tccctgcggg tgctcgacgg ggcggtggcg gtgttcgacg ccgtcgcggg cgtggaaccg
    21841 cagagcgagt ccgtgtggcg gcaggccgac cggcacggcg taccgaggat cgcgttcgtc
    21901 aacaagctcg acagggtggg cgccgacctc gatgccgcgg tggcgtcgat ccgggaccgg
    21961 ctccatccgg tcccgctggt cgtgcaactg ccgataggca cggaggacgg cttcaccggc
    22021 gtcgtcgacc tcctgcgcat gcgagccctg acctggggcg acggtggcgg gacggcggtc
    22081 gaggacgccg tgccggagga cctccgggag gaggcgctgc gccggcgccg gctgctggag
    22141 gaagccgtgg cggagcggca cccgggcgcg ctggaggagt tctgcgaccg ggagaccctc
    22201 tccgccgaga ccctctccgg tgccctgcgc gagctgaccc ggacgggcga cgcggtggtc
    22261 gtgctgtgcg gctcggccta ccgcaaccgc gggatcgaac cgctgctcga cgccgtcgtc
    22321 gcctatctgc cgtcgccgtc ggacgtgccg ccggtatgcg gtatgcctgg tggcgccgcc
    22381 ggtatgcgaa ataccaagga cggtgtgcgt gacgccgccg acggtatgca cagcactgtc
    22441 cacggtatgc acgaagcagc cgaccgtcgg cgcgagcgtg ccgatcgtat gcaggatgcc
    22501 gtaggcgaac aacgacccgc cgaccccgcc gcacccttcg cggcgctcgc gttcaaggtc
    22561 gccgcgaccc ccacgggccg gctcacctat ctgcgggtgt actcgggcac gatcgagaaa
    22621 ggagacgcgg tgtgggagtc cggcgcgcgg cgcatcgagc ggatcggccg gatcctgcgg
    22681 gtgcaggccg accggcacgc acagctggaa cgcgcggtcg ccggggacat cgtggccgtg
    22741 atcgggctga agtcggcccg tgcgggttcg acgctgagcg cgccgggggc gccccttgtc
    22801 ctcgaaccgc cgggggtcgc cgacccggtc gtctccgtgg cggtcgaggc acgtgcgagc
    22861 accgacgccg accggctggt ctcggcgctc gcccggctgg ccgaggagga tccctcgctg
    22921 gtcgtgcgga ccgacccgga gaccggtcag acgctgctgt cgggcatggg ggaactgcac
    22981 ctggaggtgg cggtggagaa gatccggcgc agcctcggtc tggaggtcaa cgtgggccgt
    23041 ccgagggtgt cgtaccgcga gacggtcgcc cgtggggtgt ccggcctggt cttccggcac
    23101 gtcaaacagg acggtggggc agggcagttc gcacacatcg tgctcgacgt cgagcccctc
    23161 gacgcggaga cggcgggagg tgttgccgaa accggtttca cgttccggtc gaccgtcgtc
    23221 ggtgggcggg tgccgcagga gtacgtccgc gcggtcgagg ccggctgccg tgacgccctc
    23281 gccgaggggc ccgtgggcgg gcatccggtc accgggctgc gggtcaccct gaccgacggg
    23341 gcgacccatg tgaaggactc ctccgagatg gccttccgca cggccggccg gctcgggctg
    23401 cgggaagccc tgcgcggctg tgcgatggtc gtgctggaac cggtcgtcga ggtcacggtg
    23461 accgttcccg aggacgccgt cggcggggtc ctcggcgacc tggcggcacg gcgcggccgg
    23521 gtcggcgact cggcggtgcg cggcggttcg gcggtggtca ccgccaccgt gccgctggcc
    23581 gaactgttcg gctacgcgac gcggctgcgc agccggaccc agggccgggg caccttctcg
    23641 gcccggccga cgggatacgc cccggcgccg gcggtggcca cgacgcggta ggcccgggcc
    23701 ctcccgcgag gtcgtgggcc caggccgccc tgtcggtccg tgccacggac acctgacgtt
    23761 cgtggcacgg accgaaggcg cccgtcgtcc ccgaggtgcg tgcggcgcgg gccgtctccg
    23821 ctcaggaccg tctacgccgt acgggcaggt cagggatacg acaccacggt cgacggcacc
    23881 gtcgaggtac cggaggtcgg cgccccgagg tcgttgatga cgtgctcgta ctggccctgt
    23941 ccgcccaggg agaccaccag caggtcgtgg aacttcacgc ccggtacgtt cggggcggcg
    24001 a
//
