GCF_001421115.1 - 4 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

NZ_JXCW01000008.1 (Apilactobacillus kunkeei)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 2.1	lanthipeptide-class-i	1	18,366	Low	cesin A	ribosomal:RiPP

NZ_JXCW01000001.1 (Apilactobacillus kunkeei)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 3.1	RiPP-like	54,172	66,322

NZ_JXCW01000004.1 (Apilactobacillus kunkeei)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 6.1	terpene-precursor	134,847	155,740
Region 6.2	T3PKS	256,294	297,460

No secondary metabolite regions were found in these records:: NZ_JXCW01000007.1 (Apilactobacillus kunkeei); NZ_JXCW01000002.1 (Apilactobacillus kunkeei); NZ_JXCW01000003.1 (Apilactobacillus kunkeei); NZ_JXCW01000005.1 (Apilactobacillus kunkeei); NZ_JXCW01000006.1 (Apilactobacillus kunkeei)

Compact view

NZ_JXCW01000008.1 - Region 1 - lanthipeptide-class-i

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Location: 1 - 18,366 nt. (total: 18,366 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-i: (((Lant_dehydr_N or Lant_dehydr_C) and cds(LANC_like and not Pkinase)) and not (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: protease

RZ55_RS07015: alkaline serine protease, subtilase family

smcogs: SMCOG1075: alkaline serine protease, subtilase family

Lyases: cyclase dehydratase

RZ55_RS06985: Lantibiotic dehydratase domain protein

smcogs: SMCOG1155: Lantibiotic dehydratase domain protein

RZ55_RS07010: Lanthionine synthetase C family protein

smcogs: SMCOG1140: Lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000538.3	0.55	ribosomal	nisin Z	Lactococcus lactis
BGC0000542.3	0.51	ribosomal	paenicidin B	Paenibacillus terrae
BGC0000556.5	0.50	ribosomal	streptin	Streptococcus pyogenes
BGC0002323.2	0.50	ribosomal	nisin J	Staphylococcus capitis
BGC0000506.4	0.48	ribosomal	entianin	Bacillus subtilis subsp. spizizenii
BGC0001618.3	0.48	ribosomal	hyicin 3682	Staphylococcus hyicus
BGC0002635.2	0.47	ribosomal	daspyromycin A, daspyromycin B	Actinokineospora diospyrosa
BGC0001210.5	0.47	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000541.5	0.47	ribosomal	paenicidin A	Paenibacillus polymyxa
BGC0000539.5	0.46	ribosomal	nukacin ISK-1	Staphylococcus warneri

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000538.3	0.55	ribosomal	nisin Z	Lactococcus lactis
BGC0000542.3	0.51	ribosomal	paenicidin B	Paenibacillus terrae
BGC0000556.5	0.50	ribosomal	streptin	Streptococcus pyogenes
BGC0002323.2	0.50	ribosomal	nisin J	Staphylococcus capitis
BGC0000506.4	0.48	ribosomal	entianin	Bacillus subtilis subsp. spizizenii
BGC0001618.3	0.48	ribosomal	hyicin 3682	Staphylococcus hyicus
BGC0002635.2	0.47	ribosomal	daspyromycin A, daspyromycin B	Actinokineospora diospyrosa
BGC0001210.5	0.47	ribosomal	pseudomycoicidin	Bacillus pseudomycoides DSM 12442
BGC0000541.5	0.47	ribosomal	paenicidin A	Paenibacillus polymyxa
BGC0000539.5	0.46	ribosomal	nukacin ISK-1	Staphylococcus warneri

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for RZ55_RS06985

RZ55_RS07215

Leader:

MSNFNDFNLGIKKVHSGSKKGLEPR

Core:

ITSYVLCTPGCITGRLMGCNNKTKTCHCHSSHNFSFHAR

Core with dehydrations:

IDhbDhaYVLCysDhbPGCysIDhbGRLMGCysNNKDhbKDhbCysHCysHDhaDhaHNFDhaFHAR

antiSMASH-DB 4.0 matches for RZ55_RS07215

100.0%

NZ_JXCW01000008.1:

Lanthipeptides: RZ55_RS07215_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHCHSSHNFSFHAR

94.9%

NZ_AP019008.1and 1 other:

NZ_BDDX01000012.1 Lanthipeptides: FF306_RS05510_lanthipeptide

Lanthipeptides: FF306_RS00060_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHCHSSHNFSFHAR

ITSYVLCTPGCITGRLMGCNNKTKTCHCHSS++FSFHAR

ITSYVLCTPGCITGRLMGCNNKTKTCHCHSSNHFSFHAR

56.4%

NZ_CP065984.1and 2 others:

NZ_CP095737.1 Lanthipeptides: MXM90_RS03205_lanthipeptideNZ_JAQDXJ010000021.1 Lanthipeptides: PGU19_RS11740_lanthipeptide

Lanthipeptides: I6I21_RS02785_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHC

ITS LCTPGC TG LMGCN KT TCHC

ITSISLCTPGCKTGALMGCNMKTATCHC

with 116 more sequence matches

Only the first 10 are displayed here.

56.4%

NZ_FNDP01000013.1:

Lanthipeptides: BLP54_RS11230_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHC

ITS LCTPGC+TG LMGCNNKT TC+C

ITSKSLCTPGCVTGVLMGCNNKTATCNC

53.8%

NC_013656.1and 20 others:

NC_020450.1 Lanthipeptides: LILO_RS03015_lanthipeptideNZ_CP009472.1 Lanthipeptides: LG36_RS03420_lanthipeptideNZ_CP010050.1 Lanthipeptides: QI18_RS03300_lanthipeptideNZ_CP015903.1 Lanthipeptides: LLUC08_RS03255_lanthipeptideNZ_CP024954.1 Lanthipeptides: CV702_RS02990_lanthipeptideNZ_CP066300.1 Lanthipeptides: LacL0098_RS03205_lanthipeptideNZ_CP098790.1 Lanthipeptides: M5C73_RS03405_lanthipeptideNZ_JAALEQ010000006.1 Lanthipeptides: HFD15_RS10120_lanthipeptideNZ_JAJONJ010000005.1 Lanthipeptides: LSG16_RS07195_lanthipeptideNZ_JAQDWM010000007.1 Lanthipeptides: PGU01_RS08180_lanthipeptideNZ_JAQDXV010000018.1 Lanthipeptides: PGT80_RS11850_lanthipeptideNZ_JAQDYA010000007.1 Lanthipeptides: PGT72_RS09560_lanthipeptideNZ_JAQDYA010000007.1 Lanthipeptides: PGT72_RS09560_lanthipeptideNZ_JAQEIZ010000019.1 Lanthipeptides: PGX18_RS12025_lanthipeptideNZ_JAQEOU010000022.1 Lanthipeptides: PGV42_RS12330_lanthipeptideNZ_JAQEOV010000015.1 Lanthipeptides: PGW09_RS10765_lanthipeptideNZ_MTJP01000006.1 Lanthipeptides: BW151_RS03795_lanthipeptideNZ_MTJR01000005.1 Lanthipeptides: BW153_RS02980_lanthipeptideNZ_MTJS01000002.1 Lanthipeptides: BW154_RS09850_lanthipeptideNZ_RAGL01000022.1 Lanthipeptides: D6108_RS11395_lanthipeptide

Lanthipeptides: LLKF_RS13210_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHC

ITS LCTPGC TG LMGCN KT TC+C

ITSISLCTPGCKTGALMGCNMKTATCNC

53.8%

NZ_CP090412.1and 3 others:

NZ_QSTB01000004.1 Lanthipeptides: DXC22_RS03785_lanthipeptideNZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptideNZ_VSTZ01000009.1 Lanthipeptides: FYK98_RS07445_lanthipeptide

Lanthipeptides: LZF92_RS09890_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHCH

ITSY LCTPGC TG LMGC KT +C CH

ITSYSLCTPGCKTGALMGCTMKTASCGCH

53.8%

NZ_FBTD01000003.1:

Lanthipeptides: PB1E_RS03075_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHCH

ITS LCTPGC TG LMGCN KT +C CH

ITSVSLCTPGCKTGALMGCNMKTASCGCH

51.3%

NZ_CP013655.1and 2 others:

NZ_CP013655.1 Lanthipeptides: ATZ35_RS03635_lanthipeptideNZ_CP013655.1 Lanthipeptides: ATZ35_RS03630_lanthipeptide

Lanthipeptides: ATZ35_RS03640_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHCH

ITS LCTPGC+TG LMGC KT TC+C

ITSKSLCTPGCVTGVLMGCALKTITCNCS

51.3%

NZ_CP059471.1and 3 others:

NZ_FNZW01000001.1 Lanthipeptides: BMZ61_RS02110_lanthipeptideNZ_FOYC01000001.1 Lanthipeptides: BMZ88_RS03370_lanthipeptideNZ_KE384124.1 Lanthipeptides: G597_RS0106700_lanthipeptide

Lanthipeptides: H1R75_RS06635_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHCH

ITS LCTPGC TG LM C KT TC CH

ITSKSLCTPGCKTGALMTCPIKTATCGCH

51.3%

NZ_JADNFO010000025.1:

Lanthipeptides: I2C89_RS09745_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHC

ITSY LCTPGC TG LM C+ KT TC+C

ITSYSLCTPGCKTGVLMACHLKTATCNC

51.3%

NZ_LR793265.1:

Lanthipeptides: HV392_RS09825_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHCH

ITSY LCTPGCITGRLMGC ++ C+ H

ITSYSLCTPGCITGRLMGCQFQSAGCNVH

48.7%

NC_015600.1and 14 others:

NZ_AP020310.1 Lanthipeptides: SAGCMC97051_RS07300_lanthipeptideNZ_ATVP01000001.1 Lanthipeptides: G574_RS11150_lanthipeptideNZ_BCFB01000042.1 Lanthipeptides: GOZ36_RS07980_lanthipeptideNZ_CP068708.1 Lanthipeptides: JM964_RS04040_lanthipeptideNZ_CP116958.1 Lanthipeptides: M0P28_RS07755_lanthipeptideNZ_CP116958.1 Lanthipeptides: M0P28_RS07755_lanthipeptideNZ_FIKS01000005.1 Lanthipeptides: A0525_RS10015_lanthipeptideNZ_GL636070.1 Lanthipeptides: HMPREF9171_RS106200_lanthipeptideNZ_JADPLU010000018.1 Lanthipeptides: I4V82_RS09545_lanthipeptideNZ_JAKVIE010000017.1 Lanthipeptides: MK857_RS08340_lanthipeptideNZ_JAQDQV010000001.1 Lanthipeptides: PGO74_RS00635_lanthipeptideNZ_JAQDQV010000001.1 Lanthipeptides: PGO74_RS00635_lanthipeptideNZ_LR594050.1 Lanthipeptides: FGL20_RS03485_lanthipeptideNZ_SSXN01000004.1 Lanthipeptides: FAJ36_RS04715_lanthipeptide

Lanthipeptides: SGPB_RS10680_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHCH

+TS LCTPGC TG LM C KT TC CH

VTSKSLCTPGCKTGILMTCAIKTATCGCH

48.7%

NC_022237.1and 1 other:

NZ_JUZI01000019.1 Lanthipeptides: ADI02_RS09325_lanthipeptide

Lanthipeptides: SII_RS05025_lanthipeptide

ITSYVLCTPGCITGRLMGCNNKTKTCHCH

+TS +CTPGC+TG LMGCN +T TC+CH

VTSVFMCTPGCVTGALMGCNLQTATCNCH

MIBiG 4.0 matches for RZ55_RS07215

56.4%

BGC0000535.4 (ADJ56352.1):

Lanthipeptide: nisin A

ITSYVLCTPGCITGRLMGCNNKTKTCHC

ITS LCTPGC TG LMGCN KT TCHC

ITSISLCTPGCKTGALMGCNMKTATCHC

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (1):

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 20.31 out of 25.88

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

RZ55_RS07215 - Class I

Cleavage pHMM score: 9.10

RODEO score: 17

Monoisotopic mass: 4162.0 Da

Molecular weight: 4164.8 Da

Number of bridges: 5

Alternative weights: (assuming N unmodified Ser/Thr residues); 4182.8 Da N = 1; 4200.8 Da N = 2; 4218.8 Da N = 3; 4236.9 Da N = 4

TFBS definitions

Regulator	Description

NZ_JXCW01000001.1 - Region 1 - RiPP-like

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Location: 54,172 - 66,322 nt. (total: 12,151 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: oxidoreductase

RZ55_RS00275: pyridine nucleotide-disulfide oxidoreductase

smcogs: SMCOG1175: pyridine nucleotide-disulfide oxidoreductase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000558.5	0.48	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0000623.3	0.48	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000617.5	0.44	ribosomal	coagulin	Bacillus coagulans
BGC0000504.5	0.43	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0001863.4	0.43	ribosomal, terpene	bacillicn CER074	Bacillus mycoides
BGC0001861.4	0.43	ribosomal	bacillicin BAG2O	Bacillus cereus BAG2O-1
BGC0000500.5	0.43	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0002579.2	0.42	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0000624.3	0.41	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0002698.2	0.40	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000558.5	0.48	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0000623.3	0.48	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000617.5	0.44	ribosomal	coagulin	Bacillus coagulans
BGC0000504.5	0.43	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0001863.4	0.43	ribosomal, terpene	bacillicn CER074	Bacillus mycoides
BGC0001861.4	0.43	ribosomal	bacillicin BAG2O	Bacillus cereus BAG2O-1
BGC0000500.5	0.43	ribosomal	carnolysin A1, carnolysin A2	Carnobacterium maltaromaticum
BGC0002579.2	0.42	ribosomal	carnobacteriocin XY	Carnobacterium maltaromaticum
BGC0000624.3	0.41	ribosomal	salivaricin CRL1328 α peptide, salivaricin CRL1328 β peptide	Lactobacillus salivarius
BGC0002698.2	0.40	ribosomal	phaeornamide	Pseudophaeobacter arcticus DSM 23566

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

No hits above weak threshold.

Weak hits (1):

RicR

Description: Copper-responsive regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 21.26 out of 32.93

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description

NZ_JXCW01000004.1 - Region 1 - terpene-precursor

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Location: 134,847 - 155,740 nt. (total: 20,894 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: formyltransferase

RZ55_RS03455: methionyl-tRNA formyltransferase

smcogs: SMCOG1228: methionyl-tRNA formyltransferase

Ligases: synthetase

RZ55_RS03490: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.38	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0001605.3	0.38	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0000639.3	0.38	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.37	terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0000678.5	0.36	terpene	pentalenolactone	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0000531.3	0.36	ribosomal	mutacin I	Streptococcus mutans
BGC0000665.5	0.35	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0000533.3	0.34	ribosomal	mutacin III	Streptococcus mutans

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.38	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0001605.3	0.38	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0000639.3	0.38	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.37	terpene	carotenoid	Enterobacteriaceae bacterium DC413
BGC0000678.5	0.36	terpene	pentalenolactone	Streptomyces avermitilis MA-4680 = NBRC 14893
BGC0000531.3	0.36	ribosomal	mutacin I	Streptococcus mutans
BGC0000665.5	0.35	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0000533.3	0.34	ribosomal	mutacin III	Streptococcus mutans

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor		FPP	C15	acyclic	PP

Genes with terpene domains:

RZ55_RS03490: PT_FPPS_like

Domain 1 (35 - 283): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:: DMAPP, IPP → FPP

Transcription Factor Binding Sites

Binding sites found:

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 21.95 out of 28.19

Confidence: medium

Additional weak hits (3):

RutR

Description: Regulator of the pyrimidine and purine metabolism
Species: Escherichia coli str. K-12 substr. MG1655
Score: 20.23 out of 26.85

Confidence: weak

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 23.96 out of 31.73

Confidence: weak

NrtR

Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 24.22 out of 35.63

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
ZuR variant 1	Zinc-responsive repressor

NZ_JXCW01000004.1 - Region 2 - T3PKS

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Location: 256,294 - 297,460 nt. (total: 41,167 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

RZ55_RS04095: dehydrogenase

smcogs: SMCOG1072: dehydrogenase

Transferases: acyltransferase

RZ55_RS04110: acyltransferase

smcogs: SMCOG1141: acyltransferase

Hydrolases: back translocase

RZ55_RS04195: GTP-binding protein LepA

smcogs: SMCOG1190: GTP-binding protein LepA

Ligases: synthase

RZ55_RS04135: hydroxymethylglutaryl-CoA synthase

smcogs: SMCOG1043: hydroxymethylglutaryl-CoA synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000255.5	0.38	PKS	pederin	Uncultured bacterium
BGC0002363.3	0.35	ribosomal	berninamycin K, berninamycin J, berninamycin A, berninamycin B	Streptomyces sp.
BGC0000913.3	0.33	other (other)	MK-8	Enterobacter cloacae
BGC0000615.4	0.33	ribosomal	TP-1161	Nocardiopsis sp. TFS65-07
BGC0001322.3	0.33	terpene	lycosantalonol, β-phellandrene	Solanum lycopersicum
BGC0002287.2	0.32	NRPS	mutanocyclin, leuvalin, tyrvalin	Streptococcus mutans
BGC0001380.3	0.31	saccharide	salecan	Agrobacterium sp. ZX09
BGC0001387.5	0.30	other (other)	nucleocidin	Streptomyces calvus
BGC0001321.3	0.30	terpene	monoterpenes-diterpenes	Solanum habrochaites
BGC0001765.3	0.30	saccharide	salecan	Agrobacterium tumefaciens

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000255.5	0.38	PKS	pederin	Uncultured bacterium
BGC0002363.3	0.35	ribosomal	berninamycin K, berninamycin J, berninamycin A, berninamycin B	Streptomyces sp.
BGC0000913.3	0.33	other (other)	MK-8	Enterobacter cloacae
BGC0000615.4	0.33	ribosomal	TP-1161	Nocardiopsis sp. TFS65-07
BGC0001322.3	0.33	terpene	lycosantalonol, β-phellandrene	Solanum lycopersicum
BGC0002287.2	0.32	NRPS	mutanocyclin, leuvalin, tyrvalin	Streptococcus mutans
BGC0001380.3	0.31	saccharide	salecan	Agrobacterium sp. ZX09
BGC0001387.5	0.30	other (other)	nucleocidin	Streptomyces calvus
BGC0001321.3	0.30	terpene	monoterpenes-diterpenes	Solanum habrochaites
BGC0001765.3	0.30	saccharide	salecan	Agrobacterium tumefaciens

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

RpoN

Description: Regulator of nitrogen assimilation and virulence
Species: Salmonella & Vibrio sp.
Score: 18.25 out of 18.46

Confidence: strong

LexA variant 2

Description: Repressor of DNA damage response
Species: Bacillus subtilis subsp. subtilis str. 168
Score: 21.88 out of 24.78

Confidence: medium

Additional weak hits (3):

MatP

Description: Cell cycle regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 18.92 out of 25.75

Confidence: weak

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.30 out of 30.25

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 23.09 out of 29.38

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
LexA variant 2	Repressor of DNA damage response
RpoN	Regulator of nitrogen assimilation and virulence