LOCUS       NZ_CP013023            24768 bp    DNA     circular CON 05-MAR-2024
DEFINITION  Paenibacillus bovis strain BD3526 chromosome, complete genome.
ACCESSION   NZ_CP013023
VERSION     NZ_CP013023.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus bovis
  ORGANISM  Paenibacillus bovis
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 5354277)
  AUTHORS   Gao,C., Han,J., Liu,Z., Xu,X., Hang,F. and Wu,Z.
  TITLE     Paenibacillus bovis sp. nov., isolated from raw yak (Bos grunniens)
            milk
  JOURNAL   Int J Syst Evol Microbiol 66 (3), 1413-1418 (2016)
   PUBMED   26769366
REFERENCE   2  (bases 1 to 5354277)
  AUTHORS   Wu,Z., Gao,C., Liu,Z. and Zheng,H.
  TITLE     Direct Submission
  JOURNAL   Submitted (21-OCT-2015) Starter Culture Research Department, State
            Key Laboratory of Dairy Biotechnology, Bldg 2, No. 1518, West
            Jiangchang Road, Shanghai 200436, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP3 v. Sep-2015
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 136.0x
            Sequencing Technology             :: PacBio; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 03/05/2024 03:10:14
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,833
            CDSs (total)                      :: 4,715
            Genes (coding)                    :: 4,671
            CDSs (with protein)               :: 4,671
            Genes (RNA)                       :: 118
            rRNAs                             :: 10, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 86
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 44
            CDSs (without protein)            :: 44
            Pseudo Genes (ambiguous residues) :: 0 of 44
            Pseudo Genes (frameshifted)       :: 21 of 44
            Pseudo Genes (incomplete)         :: 22 of 44
            Pseudo Genes (internal stop)      :: 3 of 44
            Pseudo Genes (multiple problems)  :: 2 of 44
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:49:46
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1739837
            Orig. end                         :: 1764605
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP013023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24768
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lassopeptide"
                     /region_number="3"
                     /rules="(PF13471 and Asn_synthase or micJ25 or mcjC)"
                     /tool="antismash"
     cand_cluster    1..24768
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /kind="single"
                     /product="lassopeptide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24768
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14768](+)"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14768
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PF13471 and Asn_synthase or micJ25 or
                     mcjC)"
                     /neighbourhood="10000"
                     /product="lassopeptide"
                     /protocluster_number="1"
     misc_feature    603..615
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 21.08"
                     /tool="antismash"
     misc_feature    complement(3166..3181)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.03"
                     /tool="antismash"
     misc_feature    complement(3455..3473)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 25.02"
                     /tool="antismash"
     gene            complement(3586..4062)
                     /gene="infC"
                     /locus_tag="AR543_RS07430"
                     /old_locus_tag="AR543_07390"
     CDS             complement(3586..4062)
                     /GO_function="GO:0003743 - translation initiation factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006413 - translational initiation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="infC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811562.1"
                     /locus_tag="AR543_RS07430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07390"
                     /product="translation initiation factor IF-3"
                     /protein_id="WP_060533167.1"
                     /transl_table=11
                     /translation="MIKNEKIKASEVHLTGLNGEDLGIMPTVEALQMARKLKVDLVCNS
                     LFSSPPPCQLISAGAARQNKQQAAKSDRPAKIKEIRLTAQIEDHDYDTKKNQALRILQS
                     GNAVTLVVKTQGSKESAKAKSIIEDLLRDLKEAGKPQTGIQVSGKQSMVQVDPV"
     gene            4272..5774
                     /locus_tag="AR543_RS07435"
                     /old_locus_tag="AR543_07395"
     CDS             4272..5774
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019450.4"
                     /locus_tag="AR543_RS07435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07395"
                     /product="copper amine oxidase N-terminal domain-containing
                     protein"
                     /protein_id="WP_060533169.1"
                     /transl_table=11
                     /translation="MKRKLWITLPLVLLLIVLSGCQAVGNLDIKNAMIRNLDVQSIESS
                     QTISVQLTPSASADAEDIQLATIVNALQLNIDSAKLQADGKMSIQGSVQYSGQKLPYHI
                     YLDEQGMTIDLEGAKQPLYISFASNDSIEGLSSLSGSFSTASLKGEEKEFAKQVISFLY
                     THLPNPSNISMNSVQQDVYGEALDLTQLHVELTGDELITLVKPFLVSVSQDKEGIRELI
                     GAVYDFMSTTLEQTEPGSAKTMLGGSRAEFVNKGYKEINEMLALVLKEYDSQLAELQES
                     KEFNTVFGPNTRVSTDVYFDKDMYIRKQSMDMTIALPDTEYTPISMIRISTASQSWNIN
                     GNVTADPVDTAGGVLQVSEKTTPGTFLRNFEKTSPVYMLLNNMNGITEKSIYFGAYGDY
                     AETITRNRVTLVPVKDLAEGLDAKMQWNAASKQLTLTDDITGAVTVLKLNSNQAVVDGQ
                     SRTLSSKVIQVKGKIYVPLRSVAGILGATVAPEGDGFTVTRK"
     misc_feature    complement(5871..5884)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 20.71"
                     /tool="antismash"
     misc_feature    complement(6064..6077)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.4"
                     /tool="antismash"
     gene            6507..7493
                     /locus_tag="AR543_RS07440"
                     /old_locus_tag="AR543_07400"
     CDS             6507..7493
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AR543_RS07440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AR543_07400"
                     /product="hypothetical protein"
                     /protein_id="WP_060533171.1"
                     /transl_table=11
                     /translation="MGLLNFKNGMVLAGALFLGTVFQSGTVHALQYGGDIVPTLSSSAG
                     SNGTAKASVEESGYEAWKAFDNNGNANSYWRAPADSTSKLSYELNQKQVVNKYTVQADT
                     YDAADAPKKWQFAGKIGNNWLVIDEQAGQSGWAPGEKRTFEVDNDVAYSGYALFITGNN
                     GSKWVGINDLELTSFEGNTNVIPAMGAPTLDAVNTPGAAASVNVESAWKAFDHSVSQDS
                     AWTSDSQRYVDASLSYTFSSPKVIKGYAIAVTAKSTAPVSWMLVGSNDGKEWDEVIHEV
                     KSSMRWEPGQKKIYAVDNTTAYKAYKLIINRNSGPTQVVVNEFELYQ"
     gene            7730..8710
                     /locus_tag="AR543_RS07445"
                     /old_locus_tag="AR543_07405"
     CDS             7730..8710
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811559.1"
                     /locus_tag="AR543_RS07445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07405"
                     /product="aldo/keto reductase"
                     /protein_id="WP_060533173.1"
                     /transl_table=11
                     /translation="MNKIMPLARRGISSSRLALGCMPFGGGWDQTPFTDEHVKEAEAAV
                     DAALSIGITMFDHADIYTKGKAEQVFGRVLNNRPELRDQIVIQSKCGIQLGDDELPGRF
                     NFSKEHILHSVDGSLERLGTDYLDILLLHRPDPLVEPDEVAEAFASLKASGKVRYFGVS
                     NMSAAQIAFLQQAIPDSFAVNQLEMSLGHLHFVDQGVHVNQAAGTAVNFAEGLMEYCRT
                     QNIQLQAWGPLAQGKFSGRDVKDQPEHIQEAAQLVQQLANEKETTPEAIVLGWLMRHPA
                     MIQPIIGTTNPQRIKACKDAERQSQLMTREEWYTLYVSARGESMP"
     misc_feature    complement(9078..9091)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.57"
                     /tool="antismash"
     misc_feature    complement(9135..9151)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 22.28"
                     /tool="antismash"
     misc_feature    9267..9280
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.61"
                     /tool="antismash"
     misc_feature    complement(9268..9281)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 20.98"
                     /tool="antismash"
     gene            9632..9922
                     /locus_tag="AR543_RS07450"
                     /old_locus_tag="AR543_07410"
     CDS             9632..9922
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AR543_RS07450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AR543_07410"
                     /product="hypothetical protein"
                     /protein_id="WP_060533175.1"
                     /transl_table=11
                     /translation="MVYTTDDKTKLVNKSLISAQSIYRSPIVTLDKPDPFSIHRTGLEP
                     YPWQKSTGICKTTSLVDHYRHRLDSYISQRDQLKQYSDQLRQETTINPHLH"
     gene            10001..11953
                     /locus_tag="AR543_RS07455"
                     /old_locus_tag="AR543_07415"
     CDS             10001..11953
                     /GO_function="GO:0004066 - asparagine synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_process="GO:0006529 - asparagine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Asn_synthase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase_7"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1177: asparagine synthase (glutamine-hydrolyzing)"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014280290.1"
                     /locus_tag="AR543_RS07455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07415"
                     /product="asparagine synthase-related protein"
                     /protein_id="WP_060533176.1"
                     /sec_met_domain="GATase_7 (E-value: 1.4e-23, bitscore:
                     81.2, seeds: 307, tool: rule-based-clusters)"
                     /sec_met_domain="Asn_synthase (E-value: 9.9e-20, bitscore:
                     69.5, seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATAGIWDMAKRHDHDELQQQGNRMMQSMERYPADASGIWQGEH
                     LFLGCHDQWVTPESVHQRMPHYDSVRRLAITGDVIIDNREELFSQLGLNASMHDIPDIM
                     LLLHAYDKWGEQMPRYLNGDFAFAIWDESRQQLFLARDWSGNRTLYYYQTAEKFIFAST
                     MEALFQTGDVSKKLSTPWMAEFLTTVAMEESTDIQATVYEQIKQLPPAHAMILSADKSS
                     IYQYGTLLPDEPLRLKSDGEYVEAFRDVYSRVIRAKLRTRHGVAATLSGGLDSGSVVSY
                     AAKILSGQNKPIYTYSFVPIPGFKDWTSSRLMANERPYIEETVKHVSRIHPVHDHYMNF
                     ADRSPLSEVEHWLSLMEMPYKYFENSFWIRGIFEQAQQQGAGVLLTGARGNFTISWGPA
                     IEYYGEMLKKFQWIKLYQEMKLYSQNAGIRRKKIIQQIQQSAFPRLSRTTRDLGRPDAL
                     KWINPELAERTGMAERVRRAELELVGSDTMSDQDIRLDKFSNLATANKDGAVTSKISMG
                     YGVWERDPTNDPRVIKFCLSVPYNQYVQNGMDRALIRRATAGDLPDKIRLNQKVRGLQP
                     ADWVQRMLPMWPAFTSEIREICQDPAAAAWMNTSNIMEALNEVGDSPSAEAAFNPATRL
                     LMRSLIMGRFIRSLA"
     gene            11983..12120
                     /locus_tag="AR543_RS24035"
     CDS             11983..12120
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811555.1"
                     /locus_tag="AR543_RS24035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_017811556.1"
                     /transl_table=11
                     /translation="MNMTKMEWQAPEMQVLDVNETAAGKGWKVIDWVTYDDADLYNPGS
                     "
     misc_feature    12121..12134
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 22.67"
                     /tool="antismash"
     gene            12187..12324
                     /locus_tag="AR543_RS24040"
     CDS             12187..12324
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811553.1"
                     /locus_tag="AR543_RS24040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_017811555.1"
                     /transl_table=11
                     /translation="MNQEKMQWQAPTLEVLDVNETAAGKGWKVIDWVTYDDADLYNPGS
                     "
     gene            12387..12521
                     /locus_tag="AR543_RS24045"
     CDS             12387..12521
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811554.1"
                     /locus_tag="AR543_RS24045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_145953903.1"
                     /transl_table=11
                     /translation="MNQEKMQWQAPSLEVLDVHQTAAGKGWRVIDWVTYDDADLYNPS"
     gene            12567..12704
                     /locus_tag="AR543_RS24050"
     CDS             12567..12704
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811553.1"
                     /locus_tag="AR543_RS24050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="paeninodin family lasso peptide"
                     /protein_id="WP_145953904.1"
                     /transl_table=11
                     /translation="MKNEKMQWQAPAMEVLEMNETAAGKGWKAIDWVTYDDADLYNPGS
                     "
     CDS_motif       12567..12635
                     /prepeptide="leader"
                     /note="peptide class: lassopeptide"
                     /note="predicted sequence: MKNEKMQWQAPAMEVLEMNETAA"
                     /locus_tag="AR543_RS24050_lassopeptide"
                     /aSTool="lassopeptides"
                     /tool="antismash"
     CDS_motif       12636..12704
                     /prepeptide="core"
                     /locus_tag="AR543_RS24050_lassopeptide"
                     /peptide="lassopeptide"
                     /predicted_class="Class II"
                     /score="-14.20"
                     /molecular_weight="2453.6"
                     /monoisotopic_mass="2452.1"
                     /core_sequence="GKGWKAIDWVTYDDADLYNPGS"
                     /aSTool="lassopeptides"
                     /tool="antismash"
                     /leader_sequence="MKNEKMQWQAPAMEVLEMNETAA"
                     /leader_location="[12566:12635](+)"
     misc_feature    complement(12737..12751)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            13036..13923
                     /locus_tag="AR543_RS07460"
                     /old_locus_tag="AR543_07420"
     CDS             13036..13923
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811552.1"
                     /locus_tag="AR543_RS07460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07420"
                     /product="hypothetical protein"
                     /protein_id="WP_060533178.1"
                     /transl_table=11
                     /translation="MPELQQVNNTNRSADVTVRFADLSQWAGAIATRETNFTMQPPGFM
                     FQMPDTGIFCIHEGNSITIDPAPQVSEAKLRLFVLGTCMGILLMQRDIFPLHGSALMIE
                     GQAYAFVGHSGAGKSTLAATFMQAGYPLISDDVIAVNYENGVPHVYPAYPQQKLWQESL
                     NHFGISSDQYSTLHDEYDKFAIPVGDQFYNQPVPLAGIFELVKTDEPEAKITELNRLER
                     LHIMLAHTFRGAIVPRLGLKQRHFSQVAALAGELDAYQIHRSTTAFTAPAIMEKVVQII
                     QSQNHAASRSGSNS"
     gene            14021..14323
                     /locus_tag="AR543_RS07465"
                     /old_locus_tag="AR543_07425"
     CDS             14021..14323
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811551.1"
                     /locus_tag="AR543_RS07465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07425"
                     /product="lasso peptide biosynthesis PqqD family chaperone"
                     /protein_id="WP_060533181.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.9e-27,
                     bitscore: 92.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 7.8e-16, bitscore: 56.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQMMNDTQKITQNSNYIASDMNGEKVMLDIESGKYYNLGAIGG
                     RIWDISEKPVTVDEIVAVLVQEYDVAQDVCKQQVSVFVEKMLQEGLVEVNGAAVR"
     aSDomain        14063..14302
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_AR543_RS07465_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="1.80E-29"
                     /identifier="RREFam002.1"
                     /label="AR543_RS07465"
                     /locus_tag="AR543_RS07465"
                     /protein_end="94"
                     /protein_start="14"
                     /score="92.6"
                     /tool="antismash"
                     /translation="NSNYIASDMNGEKVMLDIESGKYYNLGAIGGRIWDISEKPVTVDE
                     IVAVLVQEYDVAQDVCKQQVSVFVEKMLQEGLVEV"
     gene            14364..14768
                     /locus_tag="AR543_RS07470"
                     /old_locus_tag="AR543_07430"
     CDS             14364..14768
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lassopeptide: PF13471"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007132650.1"
                     /locus_tag="AR543_RS07470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07430"
                     /product="lasso peptide biosynthesis B2 protein"
                     /protein_id="WP_060536682.1"
                     /sec_met_domain="PF13471 (E-value: 7.6e-23, bitscore: 78.8,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRKLMLEALFYLAWGRIMKMRPFAKVSPSLGDYMQETTYESDRDA
                     HRQAVQISKALHLVSPHVFWETECLVMAFAAMKMLERRKLPSTLYLGMRRDEKGGNAAH
                     AWLRSGRFYLTGAKEIEQYTVVGRFAKQFN"
     gene            14803..15996
                     /locus_tag="AR543_RS07475"
                     /old_locus_tag="AR543_07435"
     CDS             14803..15996
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF026257.4"
                     /locus_tag="AR543_RS07475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07435"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_060533183.1"
                     /sec_met_domain="NTP_transf_5 (E-value: 4e-64, bitscore:
                     214.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKEWGLDLRNFPVELKLMLGSMKSKPADLLLAGGESALDWQEFS
                     SLSMHHRVYPTIHAHLSAYSDLLPAETMQWLNHRYHHNTFTMLQLSGQMQKVSQAFNKQ
                     DIPALQLKGPVLAQLLYGDLSRRTSKDLDVLVPMDRIEAAEQTLLELGYTKTQEVDRTL
                     DKWKWRYNHESYTHERTGVEIELHWRLNGDAGAEQSFDDLWTRKQTMQFGGTSVHMLGK
                     EDLLIYLAVHGARHAWFRLRWLADIDRLVRMDIDWELLTRLARQYKSSHIIGQAFLLSA
                     ALLETPVTPQMEVLMNQPRARDLARRVIVFIREKVSLCPEPETERLAQKYRSYQYALRT
                     NGQKALFWWRKMTPDAWDMQTLPLPKPLHFMYYPLHPFLLLYRRNQRRSALQREVGQ"
     gene            16068..17789
                     /locus_tag="AR543_RS07480"
                     /old_locus_tag="AR543_07440"
     CDS             16068..17789
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007132649.1"
                     /locus_tag="AR543_RS07480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07440"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_227871887.1"
                     /transl_table=11
                     /translation="MLVISLLDMVTLYMLVPLLSLIGVFGGAGSSTLPMASLFAPLKQM
                     PVATTLIIILSIYSLLTIVQGLMQRKQAIMGAEIQQGFIKSLRLRVYRSIMRSNWTFFL
                     RKRKSDLSHMLTTELARVSQGTNLVLMLSTSLLFTVIQIGFAMVLSFKMTLLVMIGGGL
                     LALYSRKFVRKSKTYGDKMTQLSQDYFSGIQENLNGIKDIKSNMLESSHFDWFRNMANK
                     LEYNLIQQIRLNSATQLIYKLISVVFIVGFIVLSAQVFKLQPERSVLIVLIFARLWPRF
                     SGIQSYLEYIGALLPAFRALSKLQTECEQAEESYRPVGYGQGPVQPLQQGIRCEQVSFR
                     YSEEHGNALQNINLFIPAGQMTAVAGRSGAGKSTLIDMLMGLMEPQEGKVTVDGDVLTG
                     ERLLSWRNSIGYVAQEPFLFHSSIRENLLLVKPDASEEELWEALSFAACDEFVRNLPDG
                     LDTVIGDRGVRLSGGERQRIVLARAILRKPEVLILDEATSSLDTENEAKVQLALEKLKG
                     KITLIVIAHRLSTIRNADQVIVMDHGQIVQQGGFNQLSSETKGTFHQLLAYQTAAQ"
     gene            complement(18123..19049)
                     /locus_tag="AR543_RS07485"
                     /old_locus_tag="AR543_07445"
     CDS             complement(18123..19049)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811548.1"
                     /locus_tag="AR543_RS07485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07445"
                     /product="aldo/keto reductase"
                     /protein_id="WP_060533187.1"
                     /transl_table=11
                     /translation="MEYIQIEGARKPVSRLIKGTDYFKHDTYEKAAANLDAFLAIGGTT
                     VDTAHIYCGGESEEVLGQYMQERGNREALVILTKGAHHDQHGPRVNAEAIRSDLMTSLE
                     RLQTDFIELYGLHRDDPSVPVGTILEALNEHVEAGRVGAIGASNWTWQRLQEANDYAAS
                     HGLTGFTFSSPNLSLAKANEPFWPGCVSADRETLDWHEQTRLPLLSWSSQARGFFTGRF
                     TPEVRDNEDLVRVFYSDDNWERLRRAGELAGQKQTTTIQIALAYVLNQPFPTCALIGAQ
                     NREELLSCDEGAKINLTREELNWLDLK"
     gene            19172..20014
                     /locus_tag="AR543_RS07490"
                     /old_locus_tag="AR543_07450"
     CDS             19172..20014
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017692154.1"
                     /locus_tag="AR543_RS07490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07450"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_227871858.1"
                     /transl_table=11
                     /translation="MKGIRQTVLLTLQEQPYFCLPESVGHYHQHPEHSVLREEGALNNF
                     NIHYVASGKGYVEVEGTVHELRSGQAVLYFPHQRQRYYSSQDDPWDVRWVHFYGERLHD
                     YMIERGFHRNLLWTLRQREGWEAAHLALLDEAERHRMLHPALLSTLTYAVLAEFVHQAV
                     PLKNRRAGQAENRILSLLPQMQQQACEPFLLQDWAERAGVSEHYFCRLFKSVVEMTPME
                     FITRSRLQMAKQWLLECPDRPIGQIAEDAGYPSVSYFNRQFLAREKKTPTEYRRLYWN"
     gene            complement(20097..20714)
                     /gene="cysC"
                     /locus_tag="AR543_RS07495"
                     /old_locus_tag="AR543_07455"
     CDS             complement(20097..20714)
                     /EC_number="2.7.1.25"
                     /GO_function="GO:0004020 - adenylylsulfate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006790 - sulfur compound metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cysC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811546.1"
                     /locus_tag="AR543_RS07495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07455"
                     /product="adenylyl-sulfate kinase"
                     /protein_id="WP_060533189.1"
                     /transl_table=11
                     /translation="MTESQQSAAGSPYITRNDRERILRQKGRVLWLTGLSGSGKSTLAF
                     ALEHELFLRGQSCYVLDGDRVRQGLNSDLGFAPEDRRENLRRIGEVARILLDSGQIVIA
                     ALISPHAPDRQMVREMFQPEDFCEIYVNCSLATCEQRDPKGLYIRARSGAIPQFTGISA
                     PYDIPEQPELVINTEFLSVEESVMLIMETLELSAVPSMDLSR"
     gene            complement(20964..21689)
                     /locus_tag="AR543_RS07500"
                     /old_locus_tag="AR543_07460"
     CDS             complement(20964..21689)
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1235: polysaccharide deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811545.1"
                     /locus_tag="AR543_RS07500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07460"
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="WP_060533191.1"
                     /transl_table=11
                     /translation="MLHKQKWLFALLIAVLLIPQTATAAKSQSSGSKAHSSKVIYLTFD
                     DGPTAHTMQLLDILDQYNAKATFFMLGPHMEHFPAATKRIVKEGNGLGLHGVSHVVSKF
                     YSSPYSAYKEMKGANESLYKVTGKYTSLVRTPYGSKPYLKKSYRDIMLSTGGFHLWDWN
                     VDSLDWKYKKDHQKVYNNIMAQVKSVERRGSTPVVLMHDQPATLKVLPKVLKELKAEGY
                     HFEVLDKKNHPLNFWNDER"
     misc_feature    complement(21776..21793)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 18.4"
                     /tool="antismash"
     gene            complement(22001..22810)
                     /locus_tag="AR543_RS07505"
                     /old_locus_tag="AR543_07465"
     CDS             complement(22001..22810)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811544.1"
                     /locus_tag="AR543_RS07505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07465"
                     /product="hypothetical protein"
                     /protein_id="WP_060533192.1"
                     /transl_table=11
                     /translation="MTSAYAQAPQKATWLWNTQLIVNSTDRILSFAASQNVTLIYLQVN
                     ADLDADVYQHFIAAASAQDITVQALDGAPSWALDSRRHELQATLDWITTYQQDASANEK
                     FSGIHIDIEPYLLPEWRTDQTTVIAGWQRSVKTVVQTAHALHIPASADIPFWLHTLLTA
                     DESATLSSWMMQQYDSITIMAYRDHASGILDVAEAQLAEGDAAGTPVYIGVETNPTDEG
                     DAITFYEEGAAYLNNQLASVIQQAGAHDSFAGIAVHDYAGWSTLVNK"
     misc_feature    22836..22853
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 22.23"
                     /tool="antismash"
     regulatory      complement(22925..23019)
                     /bound_moiety="cyclic di-GMP"
                     /db_xref="RFAM:RF01051"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01051"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-GMP riboswitch class I; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    22991..23005
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.64"
                     /tool="antismash"
     misc_feature    23148..23166
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 22.92"
                     /tool="antismash"
     gene            complement(23324..24103)
                     /locus_tag="AR543_RS07510"
                     /old_locus_tag="AR543_07470"
     CDS             complement(23324..24103)
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /GO_process="GO:0000413 - protein peptidyl-prolyl
                     isomerization [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811543.1"
                     /locus_tag="AR543_RS07510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AR543_07470"
                     /product="peptidylprolyl isomerase"
                     /protein_id="WP_060533194.1"
                     /transl_table=11
                     /translation="MLRQPRKNVVFVLVCAALFLIIAGCGNNNGTSSSTSGQTGTSTST
                     ETNGSSGSTGSTGSTGDQSGSTATDTTQAPSATDNSANFKQDNDPIVTVEMDDGQKIEI
                     ELYPKAAPNSVNNFISLVKKGFYDGLTFHRVIPGFMIQGGDPKGDGTGDPGYSIPGEFQ
                     ANGVQNDLKHTAGVLSMARSGDPNSAGSQFFLMVADAPHLDGGYAAFGKVISGMEEVNK
                     IVNLPRDSNDKPNTPPVMKKVTVDTKGVDYPEPEKTK"
     misc_feature    24166..24179
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.97"
                     /tool="antismash"
ORIGIN
        1 gcatgtcctt actcacacat atatataagc atactccgca gggagttgcg atcttctcgc
       61 ctcaaggtga atgtctgcag gtcaatcccg ctttttgccg tttactggat tatgaagagg
      121 aagaattaaa gcaattcctg aatatacagc agctggcgga tagctggctg tatcaacagc
      181 agacagaccc gatcgagcgg cgtctgatgc ggcatgacca gaatatgatc tggttgtcac
      241 tacaagcttc acgctacccg gatgttccgg aacagcagct ggaatatctg gtgttgtatg
      301 ccagtgaaat taccgaccgc gaagaagaag atctgtatac gatggtcgct cgtaatgctt
      361 cgagtgtcgt atcggtcagc ttgccggatg gtacgatcaa ctatgtatca ccttcaatca
      421 aaaaagtact tggttatgaa ccttatgaag tgatgaattc caagcggatg gagtattacc
      481 atgagcagga tgcccaggat atgctccttc cgggacttat gtataacgac agcaaaacgt
      541 ttattcgccg tgccaaacac aaggatgggc attatctgtg gatcgaggtc ttcactcaga
      601 ccatgcataa tgcaaacggc gaagtagagc gaatcctcag cattgcccag gatgtcacca
      661 agcgcaaagc ccaggaagat atcgtctccc gggcacacaa gcttgcccag atcggcgcct
      721 gggactggga tatggtcaat aaccggattc atttctccaa ggacatccgc cggattttcg
      781 gtaatgtaat gaaaccggta gagctgaata ccgattcgta tatgtccacg attcatcccg
      841 acgatgccga tcatgtcatg aaatgtatta tggatgcgct tcatgatggc acgaatggag
      901 aagcactgta ccggatcata ctgccaggca atatccaaaa agtcgtgcag gcttactggg
      961 aagtcattac tgataaagct accggtacgc cactacagat tattggtatc gtgcaggatg
     1021 taaccgccaa tcaccagatg agcgagcagc ttcgtcagag cgagcataat taccgtctga
     1081 ttaccgagaa ttcgctggat atgatttccc ggcattatga tgatcaggaa ttcactttcc
     1141 gttatgtctc tccggccagc atgattattc tgggctatga accggaagag ctgatcggca
     1201 gttcctgctt tgagctgctt catcccgagg atatcgacaa agcgcgtcgc ttcctggaag
     1261 cgatcaaagg caaaggcagt cagcacgata cgatcatctt ccgttatcgg cacaaaaagg
     1321 gccattatat ctggttcgag acgctgagcc ggtatgctta taatgaacag gaaggcagct
     1381 acggctatac gtcggtctcc cgtgatatta cagagcgcaa atatctggaa atggtgctgc
     1441 gtgacagcga atatcgctac cgttcactgt tcgagaacaa tccatccggc gtatgcgcga
     1501 tggatcttca aggacacttc ctgtcagtta acagcagtct ggaagagatt accggatttt
     1561 cccggcatga gctgatcgga cgccggattt tcaacttttt ctcggcagag gacctgggca
     1621 agatcaggca tcatgcgcgc atggcagcaa aaggtgttcc gcagacctac gagatttccg
     1681 taccacgcaa agatggttcc tttttcccgg cagatgtgat caatgtgccg attatggcag
     1741 ataccgaagt tataggactg tacgggatta ttaccgaaac gacccggctc aagcagtata
     1801 tcagccagat cgaaaagctg ggtaatgaac gcgcgctgat tctggactcg gtctccgaag
     1861 gcatattcag tgtggatgcg gaaggccacg gtatatttat caaccgggct ggtgcggaaa
     1921 tgctagggct ggttatacag cagccggata gtcagggact gtacaattcc catagctgga
     1981 atcaggcact atacgatgtg gatattctga acgagcagtc gccgattatt caggcgatcc
     2041 ggcagggtac accgcatcag gaggaagaga ccgtattttg gaaaaatgac ggctccagct
     2101 tcctcgccgc gtaccgggta acaccggtat acgagcaggg tgaatatcgc ggaaccgtta
     2161 tcgtgttccg ggatattacg gatgaaaagg aaattctgcg tgccaaagaa tctgcggaaa
     2221 aagcggatcg tgccaaatcg gagtttctgt cggtgatgag ccatgaactg cgtacgccga
     2281 tgaacggcat tatgggcatg accggtctgc tggcggatac cgagctggat gaacagcagc
     2341 gcagttatct ggagattgtt atgaatagta gtgagaccct gctgcagctg ctgaatgaaa
     2401 tactcgattt cagtaaagcg gaagccggta tgctcacgct ggaaccggaa ccattcgaaa
     2461 cgacaagggt aatggattct gtcgccgagc tgttccaggt gcgcgcgtcc gagaaaggaa
     2521 cactgcttgc tgtcgaaatc gctccggaag tgccggatat acttgtcgga gatgccggac
     2581 gaattcgtca gattctgatc aatctggtag gcaatgccgt gaaattcacc gaagaaggac
     2641 agatcactgt ctcggttcgc gcactggaac gttccgaagg acagaccgat cagcctggag
     2701 aaatctggct cgaatttgct gtacaggata ccggaatcgg aattgccctg catcagcagc
     2761 atctgctgtt ccagccattc tcccagcttc atccggtctg gaatcgcaaa tatggcggca
     2821 cgggtcttgg actatcgatc tgcaaaaagc tcgtagagct gatggaaggc agtattggcg
     2881 tgatcagtga ggaaaatcag ggagccgtgt ttcggtttgt attgaagctg ggcaccgtca
     2941 ctgctgctca gccagatgat actttgctgg cgccttccgt gatttctgcc gacaatcgtt
     3001 tattgcaagc gactgtagcc catccaacgg ctcatcatcc ggaactgcgc attctgattg
     3061 ccgaagatca tccatccaac cagcgagtgc tgctttcgat gctgcaccgg gaaggataca
     3121 cggcagatct ggtggtaaac ggggaagaag cggttcaggc ttgtctggat cagacatacg
     3181 atctgatttt tatggatgta cagatgccag gcatgaatgg actggaggcg tcccagatta
     3241 tacgggggca tttcagtaat gagcagacgc cgatcattat cggtgtaacg gcgttcgccc
     3301 gccaggaaga ccgggaacgc tgcctgtctg ccggtatgca tcattttgtc agcaagccgg
     3361 tgatgaatgc ggagctgcaa agagtactgc aggagagtac ggatatgctt cggctccgtc
     3421 gtccggtcag cgaccctcag ctataaagaa tacgtgcaga ccctatacaa tatagaggct
     3481 aatcttctat aacgatacaa aagtaggatg caaaagcgga tcaccggggc tgtccctggt
     3541 gatccgcttt tttggctatg atatggggtg tttttgataa gaaaattata ccgggtccac
     3601 ctgtaccatg gattgcttgc cacttacctg aataccggtt tgtggtttgc cggcttcttt
     3661 gagatcgcgc agcaggtctt caataatcga tttggctttg gcggattcct tgctgccctg
     3721 tgttttgacg acgagtgtca cggcattgcc ggattgcagg atgcgcagtg cctgattttt
     3781 cttggtatca taatcatgat cctcaatctg ggcagtcagg cggatttctt tgattttggc
     3841 ggggcggtcg cttttggcag cttgctgctt gttttggcgg gcagctccag cagagattag
     3901 ctggcagggt gggggactgc tgaacagtga attacacacc agatccactt ttagcttgcg
     3961 ggccatttgc agggcttcga cagtaggcat aatccccaaa tcttcaccgt tcagaccggt
     4021 aagatgcact tcggatgctt tgattttttc gtttttgatc atgatgattc ctccagcagg
     4081 tctgttgatc tttcctagat atacacttta tcagctattg tatcataatc gctcttcgat
     4141 caggcacagc atgccttacg gatagctaaa tcgcctatat cgatatttac ataaaattac
     4201 aggattgttt tacaaataga tggcaaactg ggataatgaa ggggaatttc aaatatgaaa
     4261 ggagattatt catgaagaga aaattgtgga ttacccttcc gctggtactg ctgttgatcg
     4321 tattgtcagg ctgtcaggcc gttggaaatc tggatatcaa aaatgctatg attcgcaatc
     4381 tggatgtaca gtccattgaa tccagtcaga ccatatccgt tcagctaaca ccatccgctt
     4441 ccgctgatgc agaagatatt caactggcta caattgtaaa tgcattgcag ctgaatattg
     4501 acagtgccaa actgcaggca gacggtaaaa tgtctataca ggggtctgtc cagtacagcg
     4561 gacaaaaact tccgtatcac atctatctgg atgagcaggg catgacgatt gatttggagg
     4621 gcgccaaaca gccactatac atatcttttg cctccaatga ttctatcgaa ggtctgtcca
     4681 gcctgagcgg cagcttcagc accgcttctc tcaaaggaga agaaaaggaa tttgccaagc
     4741 aggtaatctc gttcctgtat acgcatctgc cgaatccatc gaatatttcg atgaattccg
     4801 tacagcagga tgtatacggt gaagcgctcg atctgaccca gctgcatgtg gagctgacag
     4861 gcgatgagct gattacactg gtgaagcctt tcctggtcag cgtttctcag gacaaagaag
     4921 gtatccggga gctaatcgga gcagtgtatg actttatgtc tactacactc gaacaaacag
     4981 agccaggctc cgccaagact atgctaggcg gcagcagagc agagtttgtg aataaaggct
     5041 acaaagaaat caatgaaatg ctggcactgg ttctcaaaga atacgatagc cagctggctg
     5101 aactgcagga gtccaaagaa ttcaataccg tatttggacc caatacccgc gtcagcacag
     5161 atgtatattt tgacaaggat atgtatatcc gcaagcagtc tatggatatg actattgcac
     5221 tgccggatac agaatataca ccgatttcga tgatccgcat ctccacagcg agtcaatcgt
     5281 ggaatattaa tggcaatgta acggctgatc cagtagatac agctggcggt gtactccagg
     5341 tatccgagaa gactacacca ggtacattcc tgcgcaattt tgaaaaaaca tctccggtat
     5401 atatgctgct gaacaatatg aacggcatta ccgagaaatc tatctatttt ggagcctacg
     5461 gagattatgc ggagacgatt acccgcaatc gtgtgactct ggttccggtc aaagatctgg
     5521 cagaaggact ggatgcgaaa atgcagtgga atgcagcctc caaacagctc accctgacag
     5581 atgatattac cggtgcagta actgtgctga agctgaactc caatcaggct gtagtagatg
     5641 gccagtcacg tacattgtct tccaaagtga ttcaggtcaa aggtaaaatc tatgtacctt
     5701 tgcgttcggt agccggtatc cttggtgcta ccgtagctcc tgaaggagac ggattcacag
     5761 taacccgtaa ataaatgtac tgcttccatc caatctatgg atagactaag aatagataaa
     5821 aggacctttc ccctgagcgg agaggtcctt ttattcattt aattttgaaa taataatgct
     5881 tatagtttgt cgaaaatagt caattggaac gcagcaatta aaagaaaggg gaatttgccg
     5941 aaaaaaatag cctcatttcg gcaaaataca gcgatggaag aacgaaaaat aaaaaagaga
     6001 taaatgagca attcgaatca tcccaattat gaatgatgaa gttaaaattt atccataaat
     6061 actttttatt agaaaaatat aggagccgca gtaaactagt cctcttatga caaaagagac
     6121 ctttacataa gatctctata atgcacataa caactgtaat tcctgtatct ttcgttcatg
     6181 atggcattgc ggcgattata ctcctgattc gccaacccaa aaggaggcag gcaaagaaaa
     6241 aataaaaact ggaaaattat aaaataatat gtaatcaagt gagtcaacaa tccaaaatat
     6301 ggttattaaa ccgtcatgga aatatcattc attttttcgg ggagaaatgg atgtagacag
     6361 tctcatcaat cttcaagctc aaacggttct atgggagtgg aactgtgatg gtactcgatg
     6421 atgtattgca cttctacaga aagctatccc atccgattta ccaaacagac ataaagatga
     6481 tttaattcaa aaggagagat tttaaaatgg gattgcttaa tttcaaaaat ggtatggtac
     6541 tggctggcgc attgtttctg gggactgttt ttcagagtgg aacagtgcat gcactgcaat
     6601 acggaggaga tatcgttccg acacttagca gcagcgcagg cagcaatggt acagccaaag
     6661 caagcgtaga agaatcgggt tatgaagcat ggaaagcttt tgacaataac ggaaatgcaa
     6721 acagctactg gagagcaccg gcagacagca catccaaact gtcctatgag ctgaaccaga
     6781 agcaggttgt taataaatat acagtacaag ccgacacgta tgatgcagca gacgcaccga
     6841 aaaagtggca gtttgctggc aaaatcggca acaactggct cgtaattgac gagcaagccg
     6901 gtcaaagtgg ctgggcaccg ggagaaaagc gtacgtttga agtggataac gatgtagctt
     6961 actccggtta tgccctgttc atcacaggca ataacggcag caaatgggta ggcatcaatg
     7021 atctggaact gacttcgttc gaaggcaata ccaatgtgat tccggcaatg ggcgcaccta
     7081 cattggatgc tgttaatacg cctggcgctg ctgcttcggt aaatgtagag tctgcctgga
     7141 aagcatttga tcactccgtg agccaagaca gtgcatggac atccgactcg cagcggtatg
     7201 ttgatgcttc cctgtcctac acattctcga gtccgaaagt gatcaaaggc tacgcgatcg
     7261 cagtaactgc caaatcaaca gcaccggtat cctggatgct ggtaggctcc aacgacggca
     7321 aagagtggga tgaagtgatt catgaggtga agtcctcgat gcgctgggag ccaggccaaa
     7381 agaaaatcta cgctgtagac aatactacag cttacaaagc ctacaaactg atcattaacc
     7441 gcaattccgg tcctactcag gtagtagtga acgaatttga actgtatcaa taaaaagaaa
     7501 tcggcagtgc agcaagccgc ttttcttaat taattccata caaaagcgaa agaagcagcc
     7561 tatgcagagg ctgcttcttt tttttggcat gctgttcaat attgccaaag caagctgccc
     7621 atcatgatcg aatattgtgg gtaatgatac gatagcttgt gcttacagat ataactatga
     7681 gaacatagac tagaaaaaag agcgctatca tcagacagga ggaaataaaa tgaacaagat
     7741 tatgccactg gcccgtcgcg gtatttccag cagtcgactc gctctcggtt gtatgccttt
     7801 tggaggcggc tgggatcaga ccccgtttac ggatgagcat gtcaaagaag cggaagctgc
     7861 tgtcgatgca gcactgtcga tcgggattac catgtttgat catgcagata tctatacaaa
     7921 aggcaaagcc gagcaggtat ttggccgtgt actgaataat cgtccggagc tgcgcgacca
     7981 gatcgtgatc cagtccaaat gcggtattca gctgggagat gatgaactgc ccggtcgctt
     8041 taatttctcc aaagaacata ttctgcattc tgtcgatggc agtctggagc gtctgggtac
     8101 ggattatctg gatattctgc tgctgcatcg tcccgatcca ctcgtcgagc cggatgaagt
     8161 ggcagaagct tttgcatcac tcaaagcttc cggtaaagta cgctattttg gcgtatccaa
     8221 tatgagtgct gcacagatcg cctttttgca gcaggcgatt ccggactcct ttgcggtaaa
     8281 tcagctggaa atgagtctgg gtcatctgca ctttgtagac caaggtgttc atgtgaatca
     8341 ggcagcaggt acggctgtga attttgccga gggtctgatg gaatactgcc ggacgcagaa
     8401 tattcagctt caggcttggg gaccgctggc acagggtaaa ttctccggtc gcgatgtgaa
     8461 ggatcaacca gagcatattc aggaagctgc ccagctggta cagcagctcg ccaatgaaaa
     8521 agaaacaaca cctgaagcga ttgtcctggg ctggctgatg cgccatccgg cgatgattca
     8581 gccgattatc ggtactacca atccgcagcg gatcaaagcc tgtaaagatg cagaacgcca
     8641 atcccagctg atgacccgtg aagagtggta caccctgtat gtgagcgcac gcggcgaatc
     8701 catgccataa cctgtacaat tcagcagaga gagtatgccc gttatgtact gcatatggga
     8761 ttgttctcat tctaaaaggt agtagacaac gaggaagctg cttatttggc tgttatatag
     8821 aaaaatcatt gtacagagga ttgtacaaat caccaatata ttgatgcgca tcaccaatgt
     8881 atggaacaga atatgcgcac aaaaagagca gaccggctat atgggtctgc tctttttata
     8941 tatctgagta ggaaaattaa atttttacag aggaaaaagc aggtaaatat gacatgagaa
     9001 gtaagcaaaa aatggaagaa ttataatcac gagatttaga tagtcaaatt gcaaatattt
     9061 taattaggta tataaaggga acgtatgatc tatgagtgga ataaatatca tatttaatta
     9121 caataaaatg tcctatgtaa caaaattgta ataaataaga gcgttttctt tttggttgcc
     9181 taagaaaatt atttaaatca aaaagcagaa atagaccatg atgataagtt agcaaattcc
     9241 cttatgttat aagggattcc accaatattt ttacttaaaa taccataaat gtaagatgag
     9301 aatccgtata agactaggac ttttgacatt taacaaatat atgaaaaaaa taatttatct
     9361 tagtaattgg aaaatttatc atgtaaatta ttcgattaga gtatataata tgttacaaat
     9421 caataaagtt attcaaaacg aataacaatt gggtaaaggt aacaatgagt tcatatgttc
     9481 aggaaaagaa ggacataaga aaataatcaa actgatgacc gatcgtgagc atcatctttc
     9541 ttttatataa agagaaggat tgtttgaagg aacgaggtct tacagtagat gtgaatgttc
     9601 gtatcggggc atgaaccgga taggaggaca aatggtgtat acaacagacg acaaaactaa
     9661 gttagtgaat aaatcactaa tctctgcaca atccatctat cgctcaccta ttgttactct
     9721 ggataaacct gatcctttca gtatccatag gactggtctc gaaccgtatc catggcaaaa
     9781 aagcacaggg atctgcaaaa cgacttctct ggtagatcat taccgtcacc gattggatag
     9841 ctatatcagc cagcgtgatc agttaaagca gtatagtgac caattacggc aggaaacaac
     9901 tattaatcct catcttcatt aattgatgca ggcatgacct atatatgaat tataaataca
     9961 ccgatattca aataatcaat cacccgaagg aggtgcaggc atgagtgcaa cagctggaat
    10021 ctgggatatg gcaaaacggc atgaccatga tgaattgcag cagcagggca atcgtatgat
    10081 gcagagtatg gagcggtacc cggcggatgc ttcgggtata tggcagggag aacatctttt
    10141 cctcggctgc catgatcagt gggtcactcc agaatcggtt catcagcgta tgccccatta
    10201 tgattcggtt cgccgactgg cgattacagg agacgtaatt attgataatc gggaagagct
    10261 gttcagccaa ttgggattga acgcttctat gcatgatata ccggatatta tgctgctgct
    10321 tcatgcctac gataaatggg gcgagcaaat gccccgttat ctgaacggtg atttcgcttt
    10381 tgcaatctgg gacgaatcca gacaacagct gtttctcgca agagactggt cgggtaaccg
    10441 tacgctgtat tattaccaga ccgccgagaa atttattttc gccagtacga tggaagctct
    10501 gttccagacc ggcgatgtaa gcaaaaaatt atctacaccg tggatggcgg aattcctcac
    10561 aaccgttgcg atggaagagt cgaccgatat tcaggcaacg gtgtacgagc agatcaagca
    10621 gctgccgcca gcacatgcga tgatcctgtc ggcagacaaa tcatccattt accaatatgg
    10681 tacgctgctg ccagacgagc cactgcggct gaagtcggat ggagaatatg tagaagcttt
    10741 ccgcgatgtg tacagccggg tgatccgtgc caagctgcgt acccgtcacg gcgtagcagc
    10801 tacgctgagc ggcggactgg actcgggcag tgtagtaagt tacgcagcca aaatcctgtc
    10861 cggtcagaac aagccgatct atacatacag ctttgtgccg attcctggct tcaaagactg
    10921 gacctcctcg cggttgatgg ctaatgaacg gccatatatt gaagagacgg tgaaacatgt
    10981 cagccggatt catccggtac atgatcatta tatgaacttt gccgatcgca gtccgctcag
    11041 cgaagtggag cactggcttt cgctgatgga gatgccttac aagtattttg agaactcctt
    11101 ctggattcgc ggtatttttg aacaggcaca gcagcaggga gccggtgtac tgcttacggg
    11161 agcacggggg aactttacga tctcctgggg accggcgatc gagtattatg gcgagatgct
    11221 caaaaagttc cagtggatca aactgtatca ggaaatgaag ctgtacagcc agaatgccgg
    11281 tatccggcgc aaaaagatta tccagcagat tcagcagtcc gcctttcccc ggttaagccg
    11341 cactacacgc gatctgggac gcccggatgc gctgaaatgg attaatccgg aactggcaga
    11401 gcggaccggg atggcggagc gggtgcgccg ggccgagctg gagctggtag gcagtgacac
    11461 catgagcgat caggatatcc ggctggacaa gttctccaat ctggcgaccg ccaacaagga
    11521 tggcgctgta acctccaaaa tatccatggg atacggcgtc tgggaacgcg acccgacgaa
    11581 tgatcctaga gtgatcaagt tctgtctgtc ggtaccgtat aaccagtatg tacaaaatgg
    11641 aatggaccgc gcgctgatcc ggcgtgcgac ggcaggagac ctgccggaca agatcaggct
    11701 gaaccagaaa gtacgtggtc tgcagcctgc cgattgggta cagcgtatgc tgccgatgtg
    11761 gcctgccttt accagcgaga tccgtgagat ctgtcaggat ccggcagctg ccgcatggat
    11821 gaacaccagc aatatcatgg aagctctaaa tgaagtggga gattcccctt cggccgaagc
    11881 ggcatttaat ccggctacac gcctgctgat gcgcagtctt attatgggac gattcatccg
    11941 cagcctagca tagcattgta taccctataa aggaggtgaa taatgaacat gacaaaaatg
    12001 gaatggcaag ctccggaaat gcaggtcctg gatgttaatg aaacagcagc tggtaaaggc
    12061 tggaaagtca ttgactgggt tacttatgat gatgccgatc tgtacaaccc gggcagctaa
    12121 ttgttgcata tcaaaggggt aagttgcacg accaatctat ccaaaacatt tgaggaggaa
    12181 atactcatga accaagaaaa aatgcaatgg caagctccaa cgttggaagt tttggatgtc
    12241 aatgaaacag cagctggtaa aggctggaaa gtcattgact gggttactta tgatgatgct
    12301 gacctgtaca acccaggtag ctaatccatt tctattacag taacaggctc acccctgaac
    12361 ccaaaacatt tgaggaggaa ataataatga atcaggaaaa aatgcaatgg caagcaccat
    12421 ccttggaagt tttggacgtg catcaaacag ctgcaggtaa aggttggaga gtcatcgact
    12481 gggttactta cgacgatgcg gatctgtaca acccgagctg atttccatat ccaacagttt
    12541 gattaacgaa taaggaggaa cacaggatga aaaacgaaaa aatgcaatgg caagctccag
    12601 caatggaagt tttggaaatg aacgaaactg ccgcaggtaa aggctggaaa gcaattgact
    12661 gggtcactta tgatgacgca gacctgtaca acccgggcag ctaatagaat tagcgccagg
    12721 tctaggctga aaggtcatcg acaacgtcga ttataaatga tgcagatttg cgaaagtctt
    12781 gctgattgtt cttggtaagc gacctgtgtt gcttcgtaag accagcaaca atgtaattct
    12841 caaagtgacc cttatacccc aaaaatgtat aagggtccat tttcttcacc aggacacaaa
    12901 catgatggaa tcaccggtgt gcattaagtt ccggaagcga tcagccaggg aacctatcgg
    12961 gaggttatta ctattaacac gatccaacaa accgtatatc aagcctttgg tctgcggatt
    13021 aaaagcgaaa tttccttgcc tgagctacag caagttaaca atacaaatag atcagccgat
    13081 gttaccgtcc gttttgcgga tttatcccag tgggcgggag ccattgctac acgtgaaacc
    13141 aattttacga tgcagccacc aggctttatg ttccagatgc ccgatacggg tatattctgt
    13201 attcacgaag gaaacagtat cacgattgat cctgcgccac aggtcagcga agccaagctg
    13261 cgtctgttcg tgctggggac ctgtatgggt attctgctaa tgcagcgtga tattttcccg
    13321 ctgcacggca gtgcactgat gattgaaggg caggcgtatg cttttgtcgg tcattcggga
    13381 gcaggtaaat caacgcttgc agctacattt atgcaggcag gctatccgct gatcagcgat
    13441 gatgtgattg ccgtcaatta cgagaatggg gtaccgcatg tgtatccagc ctatccgcag
    13501 cagaagctgt ggcaggaaag cctgaatcac tttgggatat cttcggatca gtactctacg
    13561 ctgcatgatg aatacgataa attcgcgatt ccggtcggcg atcagttcta taatcagccg
    13621 gtaccactgg caggcatatt cgaactggtg aagacggatg aaccggaagc caaaatcacg
    13681 gaactgaacc ggctggagcg tcttcatatt atgctggccc atactttccg tggagcaatc
    13741 gtgccgcgtc ttggtctgaa gcagcgtcat ttctcccagg ttgccgcact cgcaggcgaa
    13801 ctggatgcgt atcagattca tcgttcgact actgccttta ctgcacctgc tattatggaa
    13861 aaggttgttc agatcatcca atcccaaaat catgctgcat cccgttccgg cagcaacagc
    13921 tagaccgtcc ggggatgaat gtgccgagga gatcaaatca cccattataa gcaataccgg
    13981 caataaatag atcagcctat cagcgaaagg ggaaaagtta atgtccaagc aaatgatgaa
    14041 cgatacacaa aaaatcaccc agaattccaa ctatatcgcc agcgatatga atggtgaaaa
    14101 ggttatgctc gatatcgagt ccggcaagta ctataatctg ggcgcaattg gcggccggat
    14161 ctgggatatt agtgaaaaac cggttactgt agacgagatc gtcgcagtac tggtacagga
    14221 gtatgatgtt gcgcaggacg tgtgcaaaca gcaggtaagt gtatttgtag aaaaaatgct
    14281 gcaggaaggg ctggttgagg tcaatggggc tgccgttcgc taaattgtcc aaagcagcca
    14341 aactgcgcaa ctacccggct gcgatgcgca agctaatgct ggaagctctg ttttaccttg
    14401 cctgggggcg catcatgaag atgcggcctt ttgccaaagt ctctccgtcc ctgggtgatt
    14461 atatgcagga gaccacgtat gagtcggatc gggatgctca ccgtcaggcg gtgcagatct
    14521 ccaaagcgct gcatctggtc agtccacatg tgttctggga aacggaatgt ctcgttatgg
    14581 cttttgctgc gatgaaaatg cttgaacgcc gcaagctgcc aagtacactt tatctcggta
    14641 tgcgccgtga cgaaaaaggc ggcaatgccg cacatgcctg gctgagaagc ggacgctttt
    14701 atctgacagg cgccaaggaa atcgaacaat atacagtcgt cgggcggttt gccaagcagt
    14761 tcaactgaca acgattgaat acagaatata aaggagtaag ccatgaataa ggaatggggc
    14821 cttgatctac ggaacttccc tgtcgaattg aaactgatgc tgggttcaat gaagtccaag
    14881 cctgctgacc tgttactggc tggcggagaa tctgcgctgg actggcagga gttcagttcg
    14941 ctgtctatgc atcaccgtgt ttatcctacg atccatgcgc atctgtcggc gtacagcgat
    15001 ctgctgccag cagagacgat gcagtggctg aatcaccgct atcaccataa taccttcacc
    15061 atgctgcagc tcagcggcca aatgcaaaag gtcagccagg cgtttaacaa gcaggatatt
    15121 ccggctctcc agctcaaggg tccggtcctc gctcagctgc tctatgggga tctgtcccgc
    15181 cgcacgtcca aggatctgga tgtactggta ccgatggatc gtatagaagc agccgaacag
    15241 acactgctgg aacttggata taccaagacc caggaagtgg accgcacgct ggataaatgg
    15301 aaatggcgct acaatcatga atcctacacg catgaacgta ccggtgtaga gattgagctg
    15361 cactggcggc tgaacggaga tgctggtgcg gaacaaagct ttgacgatct gtggacacgc
    15421 aaacaaacga tgcagtttgg cggtacctcc gtgcatatgc tgggcaaaga agatctgctg
    15481 atctatctcg ctgtccatgg ggcacgtcat gcctggttcc ggctgcgctg gttggcggat
    15541 attgacagac tggtacgtat ggatatcgac tgggaactgc tcacacgcct ggctcgccag
    15601 tataagagca gtcatattat cggtcaggct tttctgctgt cggctgctct gctggagacc
    15661 ccggtaacac cgcagatgga agtcctgatg aatcagccgc gtgccagaga tctggctcgc
    15721 cgggttattg tatttatccg ggaaaaggtc agcctctgtc cagaaccgga aaccgagcgg
    15781 ctggcgcaaa aataccgttc ctatcagtat gcactgcgta ccaacggtca aaaagcattg
    15841 ttctggtggc gcaaaatgac gccggatgcc tgggatatgc agactctgcc gctgccgaag
    15901 ccgctgcact ttatgtatta tccgcttcat ccgtttctgc tgctgtaccg gcgcaatcag
    15961 cgccgcagtg ccctgcagcg ggaggtgggc cagtgaatga gctgcgcagc tacgtaaatg
    16021 aactacgcca atatggtggc aagcgaatct atttctatat cggtctgatg ctggtcatca
    16081 gtctgctcga tatggtaacc ctgtatatgc tcgttccgct gctcagcctg attggtgtgt
    16141 ttggcggagc aggcagcagc acgctaccga tggcctcgct gttcgcgccg ctcaagcaga
    16201 tgccggtggc gactacattg attattattt tgtcgatcta cagtctgctg acaatcgtac
    16261 agggactgat gcagcgcaag caggctatta tgggtgccga gatccagcag ggatttatca
    16321 aaagtctgcg gctgcgagtc tatcgctcga ttatgcgctc caactggacc tttttcctgc
    16381 gcaagcgcaa atcggatctt agtcatatgc tgactaccga gttggccaga gtcagtcagg
    16441 gtacgaatct ggtattgatg ctgtccactt cgctgctgtt taccgtgatc caaatcggat
    16501 tcgctatggt actgtcgttc aagatgacgc tgcttgtaat gatcggcggc ggattgctgg
    16561 ccttgtattc acgcaagttt gtccgcaaat ccaaaacgta cggagataaa atgacccagc
    16621 tatcgcagga ttatttctcc ggtattcagg agaatctgaa cggaatcaag gatatcaaaa
    16681 gcaatatgct ggagtcttcg cactttgact ggttccgcaa tatggccaac aagctggaat
    16741 ataatctgat ccagcagatt cgcctgaatt cggctaccca gctgatctac aagctgatct
    16801 cggtcgtatt cattgtcggc tttatcgtat tatccgcaca ggtattcaag ctgcagccgg
    16861 agcgttcagt gctgatcgta ctgatctttg cccggttatg gccacgattc agtggtatcc
    16921 agtcgtatct ggaatatatc ggtgctttgc tgccggcttt ccgcgcactc tccaagctgc
    16981 agaccgaatg tgaacaggcc gaagaatcat atcgtccggt tggatatggt cagggaccgg
    17041 tacagccgct gcagcagggt atccgctgtg agcaggtatc gttccgttac agcgaggagc
    17101 atggtaatgc tctgcagaat attaatctgt ttattccggc aggccagatg acggcggtcg
    17161 ccggacgctc gggagcgggc aaaagtacgc tgatcgatat gctgatgggc ctcatggagc
    17221 cgcaggaagg caaagtcact gtagatggag atgtgctgac cggagagcgt ctgctgtcct
    17281 ggcgcaactc gatcggttat gtagcacagg agccgttcct gttccacagt agtattcgtg
    17341 agaatctgct gcttgtgaag ccggatgcga gtgaggaaga gctatgggaa gcattatcat
    17401 ttgctgcctg tgacgaattt gtacggaatc tgccggatgg actggacacg gttatcggtg
    17461 accgcggtgt ccgtctgtcc ggaggagaac gtcagcgtat tgtattggca cgtgcgattc
    17521 tgcgcaagcc ggaagtgctg attctggatg aagcgaccag ctcactggat accgagaatg
    17581 aagccaaggt acagctggct ctggagaagc tgaaaggcaa gatcacattg atcgttatcg
    17641 ctcaccgtct gtccacgatt cgcaatgccg accaggtgat tgtaatggat catggccaga
    17701 ttgtgcagca gggcggattc aaccagctgt ccagcgagac caagggaacc ttccaccagc
    17761 tgctggcgta tcagacagct gcccagtaat actggatggg ctcatgcttc tttttctgac
    17821 agataaaccg ttcgctgctg aagtgaataa aattatgtgt atgcaataag atgagcgata
    17881 tgcagatcaa ccaatggtat gcaggcgaat tacaccatat gatatgaaaa aggaacagat
    17941 cactgcaatg cagtgaaatc tgttcctttt ttgatagttt ggattaagga tagtctgaat
    18001 tgattgttga tactgcagag tggattttag cagaatagta ttggatttga tgccagatca
    18061 gggtatacag caatcgttac tcttttccaa tcattcggta aatgattgtg tagagccagg
    18121 atttacttca gatccagcca gttcagttct tcgcgtgtca aattgatctt cgcaccctca
    18181 tcacaggata acagctcctc acggttctgt gctccgatca gggcacaggt cgggaaaggc
    18241 tgattgagta cataggcaag tgcaatctgg atcgtggtgg tctgcttttg tccagccagt
    18301 tctccggcac ggcgcagccg ctcccagttg tcgtcgctgt agaatacgcg taccaggtct
    18361 tcattatccc gtacttctgg agtaaatcgg ccggtaaaga agcctctcgc ctgcgaagac
    18421 caggacagca gcggcagccg ggtctgttca tgccaatcca gtgtctcgcg atcagcggag
    18481 acacagcccg gccagaacgg ttcattggct ttggcaaggc tcagattggg actgctgaac
    18541 gtaaagccgg ttaatccgtg ggaagccgcg taatcattcg cttcctgcag ccgctgccat
    18601 gtccagttgg aggctccaat agcgcctacc cgcccggctt cgacatgctc gttaagcgct
    18661 tccaaaatag tgcctacagg aacagatgga tcatcccgat gcagaccata cagctcaata
    18721 aagtcggttt gcaaccgttc cagactggtc atcagatcac tgcgaatagc ctcagcatta
    18781 acacgtggtc catgctggtc atgatgcgct cccttggtca gaatgaccag cgcttcgcgg
    18841 ttgccgcgtt cttgcatgta ttgaccgagc acttcttcgc tttcaccacc gcagtaaata
    18901 tgagcagtat ccacagtcgt gccgccaatc gccagaaaag catccagatt cgcagctgcc
    18961 ttttcataag tatcatgttt aaagtagtcg gttcctttga tcagccggga gaccggtttg
    19021 cgtgcacctt caatctggat atattccata tcgtatatct tcctttcgtg tataggatga
    19081 attacttgta tattgtgatt ataatgaatt caaaaaggct tggaaatgat aatatattga
    19141 atagattaac acaatattgt cattagagag ggtgaaagga attagacaga ccgtactgct
    19201 tacgctgcag gaacagcctt atttttgttt gccggaatcg gtcggacatt atcatcagca
    19261 tccggaacat tccgtgttga gagaagaagg ggcactaaat aatttcaata tacattatgt
    19321 agcatccggt aaaggttatg tagaggtgga agggacagtg catgagctac gcagcggaca
    19381 agccgtattg tattttccgc atcagcgtca gcggtattat agtagccagg atgatccctg
    19441 ggatgtgcgc tgggtgcatt tttatggaga acgtctgcat gattatatga ttgagcgggg
    19501 atttcaccgt aatctgctat ggacactgcg tcagcgggaa gggtgggaag cggctcatct
    19561 ggcgctgctg gatgaagcag agcggcaccg catgctgcat ccggctctgt tatccacatt
    19621 gacctatgcg gttctggccg aatttgtaca tcaggcggtt ccgctgaaga atcggcgggc
    19681 cggtcaggcc gagaaccgga ttctgagctt gctgccgcag atgcagcagc aagcctgtga
    19741 accttttttg ctgcaggatt gggcggagcg agcgggagtg agcgagcact atttttgtcg
    19801 attgttcaaa agtgtggtcg agatgactcc aatggaattt attacccgtt cccggctgca
    19861 gatggccaag caatggctgc tggaatgtcc ggaccgtccg attgggcaga ttgcagaaga
    19921 tgccggttac ccgagtgtga gctattttaa ccgtcaattt ctggcccgtg aaaagaagac
    19981 tccgacagaa tatcgcagat tgtactggaa ctaaatttac tccatgtcgg caggtataat
    20041 cattattcct gcctgacaat acatgaacag actaaatata cgctccgtca gccggatcag
    20101 cgggaaagat ccatactggg tacagcagac agttcaagtg tctccatgat cagcatcacg
    20161 gattcttcaa cagacaggaa ctcggtgttg ataacgagtt ccggctgctc cgggatatca
    20221 tagggagcgc tgattccggt gaactgggga attgctccac tgcgcgcccg aatatacaac
    20281 ccctttggat cacgctgctc acaggttgcc agagagcaat taacataaat ttcgcaaaag
    20341 tcctccggct ggaacatttc ccgcaccatc tgccgatccg gcgcgtgggg agaaataagt
    20401 gcagcgatca cgatctgccc gctatccagc aaaatacggg cgacttcgcc tatgcgtcgc
    20461 agattctcgc gccgatcttc cggggcaaag ccaagatcgc tgttcagtcc ctgccgcacc
    20521 cggtccccgt ccagtacata acaggattgt ccacgcagga acagctcgtg ctccaaggca
    20581 aaagccagtg tggatttacc tgatccggat agtccggtca gccacagtac acgtcccttt
    20641 tgccgtaaaa tccgttcgcg gtcattacgt gtgatatagg gcgaacctgc tgcggactgc
    20701 tgtgattccg tcataaatac actcctttgt acaaacaaat tgggtttatt ttatcataac
    20761 agcaatacgc cggaattgcc cgtatggaac caatgaagct ggaaaaattc tggataaaga
    20821 ctgatacagc tcactaaaac ttgataagct tggaaggaat aaaaaagaac cctgtacgca
    20881 aaaaaaatct ttttgcaaac agggttcttt ttgtacagtt gtataaactg cataggctgt
    20941 atatccggct ttggatcgcc caattagcgt tcgtcgttcc agaagttcag cggatgattt
    21001 tttttgtcta atacttcaaa atgatagcct tctgccttga gctctttgag tacttttggc
    21061 agtactttga gcgtggcggg ctgatcatgc atcagtacaa ccggagtgga gccgcgacgt
    21121 tcgaccgatt tcacctgggc cataatgttg ttgtatactt tctggtgatc ttttttgtat
    21181 ttccagtcca gggaatccac gttccagtcc cacagatgga aaccaccggt gctcagcata
    21241 atatcccggt aggatttttt gagatacggc ttgctgccgt aaggagtacg caccaggctg
    21301 gtgtacttgc cggttacttt atacaggctc tcgttggcgc ctttcatttc cttgtaggcg
    21361 ctgtagggag agctgtagaa cttgcttacc acatggctaa caccatggag accgagtccg
    21421 ttaccttctt tgacaatacg tttggtcgct gctgggaagt gttccatatg cggcccaagc
    21481 ataaagaaag tcgctttggc attgtactga tcgaggatat cgagcagctg catcgtgtgg
    21541 gcagtcggtc cgtcatcaaa agtcagatag atcactttgg atgaatgtgc tttgctgccg
    21601 gatgattgtg atttggcagc ggtcgctgtc tggggaatta atagtacagc gatgagtagt
    21661 gcgaataacc atttttgctt atgtagcatg aataaaacgc tccttacctg caaatttctg
    21721 tatctatcat aacaaggcag ccagcagtga atcttccgta aatggatact attgcataac
    21781 atttttgtta cattaatcgg cattaaacta caaaatcgtc aaattgtgaa tattgcaaat
    21841 aaaagaattg gttccaaagg tagatagata agtatttggt cgcataacaa agcacagaaa
    21901 atgaactacc catagagata aaattatctc ggtatattct ccatatatac ataaagagac
    21961 agacggaaaa gaacgtctgt ctcgatagtg aagcatcatt ttatttattt accagtgtcg
    22021 accagccggc ataatcatgc acagcaatac cggcaaaaga atcatgtgca ccagcctgct
    22081 ggatcacgct ggccagctgg ttgttcagat aggcagcgcc ttcctcgtaa aaggtgatcg
    22141 catccccttc atctgtagga ttggtctcta cacctatata gacgggagta ccggcagcat
    22201 caccttcggc aagctgggct tcggcgacat ccagaattcc ggaggcatga tcacggtaag
    22261 ccatgatcgt aatggaatca tactgctgca tcatccagct gctgagcgtc gcagattcgt
    22321 ctgcggtcaa cagggtatgc agccagaacg ggatatcggc agaagcgggg atatgcagag
    22381 catgagcagt ctgtacaaca gtcttcacac tgcgctgcca gccggcgata acggtggtct
    22441 ggtcggtacg ccattcgggc agcagataag gctcgatatc gatatggata ccgctgaatt
    22501 tctcatttgc cgaggcgtcc tgttgatacg tggttatcca gtcaagcgtg gcctgaagtt
    22561 cgtgacgccg ggaatccagc gcccaggaag gggctccatc gagtgcctgc accgtaatgt
    22621 cctgtgcaga agcggcagca ataaagtgtt ggtatacatc agcatccaga tcggcgttga
    22681 cctgcaggta gatcagggta acgttctggc tggctgcaaa agataaaatg cggtctgtgg
    22741 aattcacaat caactgtgtg ttccacagcc aggtcgcttt ctgtggcgct tgagcataag
    22801 cagatgtcat cgtgaatcct cctagcccta gtaataatgc tatacagagg atacccaatt
    22861 gtaagcgata atatgctgtt ctcatgatgt tggactcctt cgagtcatac cgcatcaggt
    22921 attcatcggc aaccggctgc cttagcacga tcctgcttgt catgccttag acccatggct
    22981 ttgcgtcttc acttttcagt gaatttgccc tgattaaata tgatagacaa tcattcagca
    23041 tgggatgctg tagtgatgaa ggctttgcca agacttcata gggtatatat cgtcggtata
    23101 gctaagtttc taaatagata attactaatt ttgcgacaaa aaatgacatt ttttataatg
    23161 tatatacgat gtgaaaaaca agctgcatag ttatggaaat atctattcag ctaagaacga
    23221 atatacacaa atagaatgac tggagataaa aagaattaac taccagcaaa aacataacag
    23281 caaaaacccg gcgctgtaga aaacgccggg ttggaaaata ggcttatttt gttttctccg
    23341 gttctggata atcgacacct ttggtgtcca cggttacctt tttcatgaca ggaggagtgt
    23401 tcggtttgtc attgctatct cttggcaggt tgacgatttt gttgacttct tccatgccgc
    23461 tgatgacttt accaaatgca gcatatccgc catccaaatg cggagcgtcc gctaccatca
    23521 ggaagaattg ggagccggcg gaattcggat cgccggaacg tgccatcgac agtacgccag
    23581 ccgtgtgctt cagatcattc tgcacgccat tggcttggaa ttcgcctggg atgctgtagc
    23641 ctggatcacc agtgccatcg cctttgggat cgccgccctg gatcataaag cccggaataa
    23701 cgcggtggaa agtcagaccg tcatagaatc cttttttgac cagggaaatg aagttattga
    23761 cgctgttcgg tgctgctttg ggatacagct cgatttcgat cttttgacca tcatccattt
    23821 cgactgttac gatcggatcg ttatcctgct tgaaattggc cgagttatca gtggcggatg
    23881 gtgcctgtgt tgtatctgtt gctgtagatc cgctctggtc gccggtgctt ccggtcgaac
    23941 ccgtgctgcc actggagccg ttcgtctctg tgctggtaga cgtaccggtc tggccggaag
    24001 tagaactgct ggttccatta ttattgccgc agccggcgat aatcaggaac agggctgcac
    24061 atacgagtac aaatacaaca tttttacgcg gttggcgtag catagatagg ttcactcctt
    24121 agtggatggt aagttccctg gcacgttgtc tggcgctagc cgatttcgag acggatcaat
    24181 catccgcaaa gaaacgtcta acgcagaaat gtgctgcaga gcatatacta tgactttaaa
    24241 ccaagccagg gctgtgaagc aaatattgac gcgtaatatt tggcagccgc taaacagaag
    24301 caggctgccg aatcaacaaa gtgttcattc cggcagcctg caggtcatct tgcatctgta
    24361 ttttttattc acggtggata tcgcaaacga tccgattatt gcagatgccc ggataatgca
    24421 atgacagcag taatcgtaaa tacattcaca attgtcgaaa tcagtaccgt ctgagcggca
    24481 aaatcgggtt cattgcgata ttcttccgcc agaatcgatg tattgacccc tgtcggcata
    24541 gcagaggcaa tcagcagcgc ctgcgctgga atcccgtgca tatcgagcag cagaatcagc
    24601 atcagaccga tcagtggacc gccaaacagc cgcagtacca tgctgatata gatatcgctg
    24661 cgatacagcc gcagtggata tttgacgatc tgcgcaccga gcgtgatcag tgcgatcgcg
    24721 accatagact gctgggcata cgtgagcggc tgggcgagta cggtcggc
//
