LOCUS       NZ_BBZG01000003        22403 bp    DNA     linear   CON 12-AUG-2024
DEFINITION  Nonomuraea pusilla strain NBRC 110462, whole genome shotgun
            sequence.
ACCESSION   NZ_BBZG01000003
VERSION     NZ_BBZG01000003.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Nonomuraea pusilla
  ORGANISM  Nonomuraea pusilla
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1
  AUTHORS   Komaki,H., Ichikawa,N., Hosoyama,A., Fujita,N. and Igarashi,Y.
  TITLE     Draft Genome Sequence of Nonomuraea sp. TP-A0861, a Producer of
            Myxochelin A
  JOURNAL   Genome Announc 3 (6), e01430-15 (2015)
   PUBMED   26659677
  REMARK    DOI:10.1128/genomeA.01430-15 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1040125)
  AUTHORS   Hosoyama,A., Kimura,A., Ichikawa,N. and Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2015) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, Biological
            Resource Center (NBRC); 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.8
            Genome Coverage                   :: 107x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001417755.1-RS_2024_08_12
            Annotation Date                   :: 08/12/2024 01:46:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,307
            CDSs (total)                      :: 8,242
            Genes (coding)                    :: 8,159
            CDSs (with protein)               :: 8,159
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1 (5S, 16S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 21 of 83
            Pseudo Genes (incomplete)         :: 72 of 83
            Pseudo Genes (internal stop)      :: 5 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:25:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 932723
            Orig. end                         :: 955126
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBZG01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22403
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..22403
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22403
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12403](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12403)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            958..1332
                     /locus_tag="ASC57_RS27955"
     CDS             958..1332
                     /EC_number="5.2.1.8"
                     /GO_function="GO:0003755 - peptidyl-prolyl cis-trans
                     isomerase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544556.1"
                     /locus_tag="ASC57_RS27955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="WP_055506180.1"
                     /transl_table=11
                     /translation="MALEKPEIDFPEGNPPADLEVVDIVEGDGPEAKPGQNVSVHYVGV
                     AFSTGEEFDASWNRGQAFEFPLGAGRVIAGWDRGVAGMKVGGRRKLVIPPHLGYGNRGA
                     GARIKPGETLIFVVDLLGVR"
     gene            1420..2973
                     /locus_tag="ASC57_RS27960"
     CDS             1420..2973
                     /EC_number="6.5.1.1"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003910 - DNA ligase (ATP) activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /GO_process="GO:0071897 - DNA biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544555.1"
                     /locus_tag="ASC57_RS27960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-dependent DNA ligase"
                     /protein_id="WP_152992573.1"
                     /transl_table=11
                     /translation="MSATCGNIGSVLLIEVVRVSEAVTRTPARLGKIGHLAELLGRVGP
                     DEAEIAISYLSGELPQRQVGVGWRTLEDLPQPKLAATATLTTVDALLSKIKAVSGQGSQ
                     AARKALVSELFAGLTSQEQQFMRRLLHGELRQGALDGVMIEAVAKASGAPSPDVRRALT
                     LRGWLPAVGAAALAGGASALREFKLEVGRAVAPMLASSAPNVAAALQKAGTPAALEWKI
                     DGIRVQGHRSGSDVRVFTRTLDDITPQVPELAEALLRLPSDDLVLDGEVIALRPDGRPH
                     PFQVTAGRASSRTNVAALREDTPLTVFFFDALRVDGTDLLDLPYTDRQEVLARTVPAEL
                     LTPRLVTDDVRAAEHFFAEAVRAGHEGLVVKSMAAPYAAGRRGAGWVKVKPRHTLDLVV
                     LAAEWGHGRREGKLSNLHLGARDPGGGYVMLGKTFKGLTDELLAWQTTRFLELAEGPTD
                     GWTVQLRPELVVEIAFDGVQRSPRYPGGMALRFARVLRYRPDKRPDQADTVDTVRSLML
                     "
     gene            complement(3064..3561)
                     /locus_tag="ASC57_RS27965"
     CDS             complement(3064..3561)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019913.4"
                     /locus_tag="ASC57_RS27965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LGFP repeat-containing protein"
                     /protein_id="WP_055506182.1"
                     /transl_table=11
                     /translation="MTTATSARPRRDRIAASLSALTLTVGALIAAAATPAHADDPHTYC
                     GLKVVGAIEERYVQMGGPTGQLGCPLTEELANPDGVGRRTQFKNGTIYWHPRTGAWPVW
                     GDIGARWCQEGCERGWLGYPTSAELRVGNEAHQNFRCGTIYWQAWPERGTMMTRLSENR
                     CS"
     gene            3747..3902
                     /locus_tag="ASC57_RS44150"
     CDS             3747..3902
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC57_RS44150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_176573480.1"
                     /transl_table=11
                     /translation="MISRVPVLPGRAPATTRIPELKELLAEEGAKIERIQNAMKDETGV
                     DHVVTA"
     gene            4438..5193
                     /locus_tag="ASC57_RS46250"
     CDS             4438..5193
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654047.1"
                     /locus_tag="ASC57_RS46250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="septal ring lytic transglycosylase RlpA family
                     protein"
                     /protein_id="WP_305728674.1"
                     /transl_table=11
                     /translation="MGQHSRHPSPQPFPDDREGGQNPHDAKPAPSRRRWTAAVAAGAAV
                     VAAVSTTAWAVTADDAPTSAAAVNLPPNPAAPASSSPKPGVSSPAPSPAAPSSVAEAAQ
                     QGNPDPSPSAAPKPPAGAEPKSSASPRPSHRRIETVARPKKKTVAAKTQARVVSSGSCG
                     ASYYDEPQMTASGERFDPSAMTAAHKTLPLGSRVRVINPNSGASVIVRINDRGPYVGGR
                     CLDLSRAAFSAIGSVGAGVMTVKYQVLAR"
     gene            complement(5384..5974)
                     /locus_tag="ASC57_RS27975"
     CDS             complement(5384..5974)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132675.1"
                     /locus_tag="ASC57_RS27975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1707 and DUF4870 domain-containing protein"
                     /protein_id="WP_055506183.1"
                     /transl_table=11
                     /translation="MAGVPVPEPWGQGHVPPAHLRVTHQDREHVVEHVKAAYAEGRFDK
                     LEFDDRLERAMTARTHGDLMPIMTELYGSNAVPHFASPSPAFRAEPAPESNERLGGALA
                     HGLAVVGFPLLGPLLLMLTGGKTSPYIRRHAVEALNFQLTLLGASILLPFTVVGIVLLP
                     VIWVAGIVLSIVGGVSALSEGAFRYPLTVRLVK"
     gene            6114..6458
                     /locus_tag="ASC57_RS27980"
     CDS             6114..6458
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017576619.1"
                     /locus_tag="ASC57_RS27980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_055506184.1"
                     /transl_table=11
                     /translation="MRWRDRYGIRRLRGAKVAKFDREATDADIEALIAFARSRRGVEFY
                     VEPETFATDTTAVAVADDGEWTRRRVGSPGVIHKVARDLALPVYDVQLTGYPPRMRAYN
                     ERRRREQDLP"
     misc_feature    6369..6371
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6987..7622)
                     /locus_tag="ASC57_RS27985"
     CDS             complement(6987..7622)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC57_RS27985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_055506185.1"
                     /transl_table=11
                     /translation="MIRQSRLSRTRALALAAATAGLAAPLLAFAGSAQAAQAAGASSQA
                     ASGKAASAAAVREEAALTCTMRTAPKNPIAFTPALRDAAAQQVKGQGVVLLEGCTSPNG
                     KVADIASGRLEVSGTATANCRGVADLSATGTVTWRDAQGQVVGTSQLTAEHKGAASLHD
                     SLLQGDVVSGRLKGRHFSGSATMTSDLRDCTAPSGFTQLTGSGKMSFA"
     gene            7707..9986
                     /locus_tag="ASC57_RS27990"
     CDS             7707..9986
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015155.4"
                     /locus_tag="ASC57_RS27990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MMPL family transporter"
                     /protein_id="WP_055506186.1"
                     /transl_table=11
                     /translation="MSVSSRPSAEGRPVAPGPPAGPGRRPLWWRLGHLAARRHRAVLTV
                     WAMLLAGSAVLIPGLLERAIAPAVRVEGSASLTGARLLEQGFPQLGGEQMMMIFASATL
                     SDADEPYQRALHDALRAVSAQPQVGGTQLLPVVPGQDHRHAYAIVGVNGDQRARQAALP
                     PLLGAAKEAASRASGGRVDVHLVGESALLAEAKHTDLADLRRAELLAVPLSLLVLLAGL
                     ASGGAALAVLAVAGTVTVTALGLLAAASLLGVPVNTFMLAVAATVGLALGLDYALLILV
                     RYRQSRAAGHDRHQAAAVAVSTAGRTAAWCAVGVALTAAALLVVRTSMIRTMGAAVSVS
                     ALVAALAAVTLLPAVLVTADRRLLRRHRLRLPAFLSRRVRALLDRPARPSASTGRPPDG
                     RRREDEHGWGRWARHLMRHPVAYTLACAGLLLAAAAPLAGVRLAFDLDRASIAGTDFGR
                     GLTAMEGDGISSSVAVALPHPAGAPPVDTAALVTTLKQDPRVSFCTSLDNGRDLTVVIV
                     IIRTHIDDPASTAMAREITGRLVPASMPPDQRAFVTGPNVIFSDLMDETTSQLGTVIPL
                     VLGCSLVFLLVTFRSVLLPLKAVLMNLLAVTAAFGLLTLATRHLPHLVGTHVNTLVPLL
                     AFTLVFGLSIDYEIFLIHRIAEHYHAGGDNTAAVVHGLRHTARPITVAAAVMVATFAAL
                     LTAHRHHLVQLGLAVATAITLDATVIRLALVPALMRILGARNWWLPAPLARLLPTPRTT
                     PPPPPH"
     gene            complement(10001..12403)
                     /locus_tag="ASC57_RS27995"
     CDS             complement(10001..12403)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="ASC57_RS27995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_055506187.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 8.3e-47, bitscore:
                     155.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALEATPETREIMLPGVRPASGDPAPAPSTGGPASSGLPASGRRG
                     TQDVPRPGLGHESWRSTVNGHESWRFTVNLRDARGEEHALMVAFLARRTPRSDGDVLLS
                     HGCGWTHSMPRSRTYQACAWRDAGGVELTSLDVSRGWDRSIAESVREACAGGRPIAPDR
                     LLPGPVTLASDRLRLDFGGVADLSVADDGGYHLVLRDDHETWDLRLRPLKPAITESGGE
                     PARELAVPPVGDAVDGDDEAREAFLVSRLAADAVWTRPGQPPVRMTGVGSYQRVHGAGE
                     LPQDAASPPADRAHTRIVLHLEDGWDVVACQSAVHDPAGGAAAGRPPSVTLVAPDGAHH
                     DVPARLDAGAPWTSIRTLNSYPTTWRVDAPRAGLALRVSACFQEQERPVLLGLGASLEA
                     AVTAEGELHGRPVRGEGWLEVEPAPRIRDLEHRIERLREVTHAEVVRLYPDSPEPGAVA
                     VLAGLAPRPAWPVDVVAEPLHRALVAPVRHLADAMGRGWRSYAAIAGMEMQGVDSQQYR
                     ALAALAELMHTASLIVDDVEDNAPMRRGRPAVHRVFGQATAINTGTHAYLVFDLVARHL
                     LPDDPERRLRLYQVYLDGMRRSHAGQALDILGHHDAMEEAVASGDAAAVLERVRTTHRL
                     KTGGVVRGVGEFGAVLAGADGEVLTAISSYFETIGLAYQISDDVADLLAVLARAGDPGA
                     RVARVPGEDIREGKVTYPLACAVTLLPQARLREIWEIVRCGGAGQAAAAEVAETLVGCG
                     ATAAALADARHAVDEAWLPLQRLLPVNHHTVMIRALGLYAAERHQDE"
     gene            12656..13687
                     /locus_tag="ASC57_RS28000"
     CDS             12656..13687
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC57_RS28000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_055506188.1"
                     /transl_table=11
                     /translation="MRTAAAILSFVLAVTFLPAGPAAAVVSAASLPGGKTTFVVSQGHL
                     KAASQQNWVRLGDYRFAANGTVSAAMYLWWQRRPQARQRTGTVPDQSCTTKAGGKQSRP
                     RTCEVLTAGGFTGAPDESRTGTYTMSGNVLTIRWKIAQAWTEQWYVRTSPDGKLARLDL
                     KQSTLATHGYGYGSNAAISTRRAMSSVKAFPRALRQDLTSWAGGKLVTAGNQPFGLSAF
                     RACSATTSCLTYLQPSSNTACQKEGGCPKYGGGTRPNVTSIQYYLTMISKSDRRDTLWH
                     WCTCLAMERGEFCYTGNSHVKPLMQIIDDTGAFRGWVGAEASFSTGSRATDMLAVLRIS
                     DFR"
     gene            complement(13695..14168)
                     /locus_tag="ASC57_RS28005"
     CDS             complement(13695..14168)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039463.3"
                     /locus_tag="ASC57_RS28005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6463 family protein"
                     /protein_id="WP_055506189.1"
                     /transl_table=11
                     /translation="MKSGKLMLRWASGIMIVLGAGHLSLLAVMAREDVARWVDRGMWAA
                     VPLELSDRGAVQTPASLQNEVTFWAGPGSFAVALILLGCLTWHLAGRGVAVPAAIGWGL
                     AAWCALGGVLLVPSPFFAGTIAGALIVLAARKGRRSEADRRAGRPAAGAREST"
     gene            complement(14165..14782)
                     /locus_tag="ASC57_RS28010"
     CDS             complement(14165..14782)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017624892.1"
                     /locus_tag="ASC57_RS28010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2867 domain-containing protein"
                     /protein_id="WP_055506190.1"
                     /transl_table=11
                     /translation="MRLPKTAFTSRPWRVHEFTRDFSVEDVWAFRTPGAGPGDFPTMLA
                     AMRAFGGLAKQPWPARFLFAVRWRLGALLGWDEPSAGVGSRVASLRDRLPGDIRDAPRG
                     PDDEGMPLKAVYELDMEAARELANRTVHTVMHLGWVQGTNGDHELRMAVLVKHNGLFGR
                     LYMTAIAPFRYLVVYPALTGRWERAWLERGRLEAEHRGGTPR"
     gene            complement(14779..16710)
                     /locus_tag="ASC57_RS28015"
     CDS             complement(14779..16710)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) SubclassB1"
                     /gene_kind="resistance"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895424.1"
                     /locus_tag="ASC57_RS28015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="WP_055506191.1"
                     /transl_table=11
                     /translation="MRWVTYATDTGDRVGVIGEDRIHPVAPDVSLIELIGRGAEELRAV
                     GEAALASAAPTVPLAEATLRAPIPRPPSIRDSLCFLDHMRACQQAAGQPRTLKDAWYEI
                     PAFYFACPSTVVGPYDDVTISPGSAWFDFELEIAAVIGRGGRDLTPEQAEERIVGYTVY
                     NDWSARDLQLREAPLAIGQAKGKDAATTLGPYLVTPDELEPYRRGDRLALRVEAAVNGR
                     VIGSGCTDAMDWSFGEVISYASRGVDLVPGDVFGSGTVPGCCLVEHLSLADPAAFPGWL
                     RDGDVVELTVEGLGRTRQTVRASAAPHPLTPRKNPDRRPPRPRVNRAPSSLPYTRGLHE
                     VGAGVWAWLLPDGGYGLSNAGLVAGEDASLLVDTLFDLPLTAEMLDAMREITDRRPLTH
                     AAVTHSNGDHTHGNQLLGEHVTIVAAEATRTEMRHEMPPEMLTATQVLDLGPATSYFRE
                     RFGAFDFSGIRLRLPDLTYEKELTLDIGGREVRLMNLGPAHTAADTVVHVPDAGVLFAG
                     DLLFVGCTPIVWSGPIANWIAACDRMIATGAHTIVPGHGPVTDPDGIRAVRGYLAHVVE
                     QADAAYARGLSYAEAAQAVDLAEYATWLDSERILVNLHRRYRELDPESTPHLDQLTLMA
                     MMAEKGLS"
     gene            16802..17374
                     /locus_tag="ASC57_RS28020"
     CDS             16802..17374
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012895423.1"
                     /locus_tag="ASC57_RS28020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_055506192.1"
                     /transl_table=11
                     /translation="MATRRIQSSEESRRLLVTAAAELFADRGYRQTSFIEIADRAGISR
                     GSIPWHFGNKLGLLKAVIDDQLDAVLAAAAPSANDRSGDPFDQVMAFIRLPVTRLFITL
                     LAEAVEVDSPIREHYARLHTALRDAARARISAEALPPGTTQEAFAVVLVGTLIGVHAQW
                     RVAPDAVDLRAVQAALRALLPAGLIEM"
     gene            17454..17918
                     /locus_tag="ASC57_RS28025"
     CDS             17454..17918
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011133468.1"
                     /locus_tag="ASC57_RS28025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_055506193.1"
                     /transl_table=11
                     /translation="MAIDNEAGRCVSADIAAGISPAAALFHSLADENRLRIVARLARGE
                     ARVVDLVGELGLAQSTVSKHLACLRDCDLVDYRAEGRQSFYSLTRPELMDLLASAEHLL
                     AATGHTVALCPVHGTRHGGAGAHDALQAELDHDLEHLDQQADEIEGKAVS"
     gene            17915..18625
                     /locus_tag="ASC57_RS28030"
     CDS             17915..18625
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891521.1"
                     /locus_tag="ASC57_RS28030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cation transporter"
                     /protein_id="WP_055506194.1"
                     /transl_table=11
                     /translation="MTALDLPAPDRRTVLRRRIRLLVAATITYNVIEAVVALTAGAAAS
                     SAALIGFGLDSVVEVASAAAVAWQFSATDHERREKTALRVIAVSFFALAAYVTFDAVRA
                     LLGVGEAGPSTPGLVLATLSLVIMPFLSYAQRRAGRELGSASAVADSKQTLLCTYLSGV
                     LLVGLALNSLFGWSWADPIAALVIAAVAVKEGREAWRGDACRAVPTSTSGSITSEPEGR
                     ADGCCVHDTQKDKR"
     gene            18622..18972
                     /locus_tag="ASC57_RS28035"
     CDS             18622..18972
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891522.1"
                     /locus_tag="ASC57_RS28035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3703 domain-containing protein"
                     /protein_id="WP_152992561.1"
                     /transl_table=11
                     /translation="MIGRPMPARVRASYRAEMRAARTAVTPEARWRHLERAHIISQPWP
                     WPHTRNHLAMFALAVAQRDRREAFGQVIRIIVAAPGSALGRYPEGNTGRATVGLTQPMP
                     VPDDLAALLRAT"
     gene            complement(19033..19242)
                     /locus_tag="ASC57_RS28040"
     CDS             complement(19033..19242)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC57_RS28040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_055506195.1"
                     /transl_table=11
                     /translation="MSADTVVVPALPGDYVEGDARLDPDLPDALRAAHGRDARMVSLRT
                     GAFALAAGWARRATSGTTSPARSA"
     gene            19399..20178
                     /locus_tag="ASC57_RS28045"
     CDS             19399..20178
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="ASC57_RS28045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_055506196.1"
                     /transl_table=11
                     /translation="MPSSTASATTAGLFTPAYCLGVLAALLLFGRISDSWGRRPAILAG
                     LAGLLVSLGMFLTASGVGRLFVARGLQGVATGVAISAAGAALLDLRPAAAGLLNTPASG
                     LGMGVGGLLGAVLVEYAPAPLLTPFVVLAAVNLLLLAGVWRRPETVGARAGFRMAAPGV
                     PREILGSFALSGLGVTSSWSIVGLYLALVPALAPALMGSAGNLPGGLAIFVMGTAAALS
                     SRRRADAQDGGHQHDRGQPLGGWHESSSRWEELIAGT"
     gene            <20499..20713
                     /locus_tag="ASC57_RS41855"
                     /pseudo=""
     CDS             <20499..20713
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014358297.1"
                     /locus_tag="ASC57_RS41855"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="IS256 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="VECTFATLRHRTKVTKGPGPEPPAWP"
     gene            20752..21456
                     /locus_tag="ASC57_RS28050"
     CDS             20752..21456
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024587.4"
                     /locus_tag="ASC57_RS28050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytidylate kinase family protein"
                     /protein_id="WP_055506197.1"
                     /transl_table=11
                     /translation="MVQGTRGELISRLAEAIRSVTAAHPLRVAIDGPPAAGKTTLADEL
                     AVVLHAQGRDIIRATIDDFLFPRAQRYRRGRYSAEGCYFDAHDHAALCRVLLDPLGAGG
                     DRRFQHAVYDRDTDTPCSPPATTAPADAVLLFDGVFLLRPELIDRWDLRIFVSVPFEQT
                     VDRARDRSTALAGSTADTAEIERSWHNRYIPSQQLYFATARPTEHADIIVYNDQLQRPT
                     WEVRPHSSIHKI"
     misc_feature    complement(20789..20803)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.19"
                     /tool="antismash"
     gene            21539..>21655
                     /locus_tag="ASC57_RS46495"
                     /pseudo=""
     CDS             21539..>21655
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025001.4"
                     /locus_tag="ASC57_RS46495"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="ParA family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDTSTAGFGKTYAVANQKGGVGKVATTIDLGGVLAEQDD"
     gene            <21691..21873
                     /locus_tag="ASC57_RS45620"
                     /pseudo=""
     CDS             <21691..21873
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558177.1"
                     /locus_tag="ASC57_RS45620"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="VVKRKVSWPAGRRRWHRRYERRADRFEPSLAIASTFSPDDRVRPF
                     VAIATALMRCRRLTR"
ORIGIN
        1 cgtcggcatc ctcacccgca ccggggcgct gcgcgccacc ctctaccagc ccgcgctcga
       61 cgccgccggc aggctgcgcg tcggcgcggc cgtcggcgtg aacggcgacg tcgccgccaa
      121 ggccaagggc ctgctcgacg ccggcgccga ctgcctcgtc gtcgacaccg cccacggcca
      181 ccaggagaag atgatcgcgg cgctgcgcgc cgtcaaggcg ctcgacccgg ccgtgcccgt
      241 cgccgccggc aacgtcgtga ccgccgccgg cgtgcgcgac ctcgtcgacg cgggcgccga
      301 catcctcaag gtcggcgtcg gccccggcgc catgtgcacc acccggatga tgaccggcgt
      361 gggccgtccc cagttctccg ccgtgctcga atgcgccacc gaggcccgca ggctcggccg
      421 ccacgtctgg gccgacggcg gcgtccgcca cccgcgcgac gtggcgctcg ccctggccgc
      481 cggcgcgtcc aacgtcatga tcggctcctg gttcgccggc acgtacgagt cgcccggcga
      541 cgcccacacc gacgccaacg ggcgcacgta caaggagaac tacggcatgg cctccgcccg
      601 cgccgtgcgg ctcaggacct ccgacgacac gccgttcgag cgggccagga aggcgctgtt
      661 cgaggagggg atctccacct cgcgcatgta cctcgacccg gtgcggccga gcgtcgagga
      721 ccagatcgac gccatcgtgg cggggctgcg ctcggcctgc acgtacgcgg gcgccgccac
      781 cctggaggag ttccacgagc gcgccgtcgt cggcgtgcag agctcgtccg gctacgccga
      841 gggcatgccg ctgcaccaga gctggtagaa gggggcggtg cgggcctccg ctgcccacgg
      901 gcgggtcccg aacgcataga gtcttcgggt ccgttctcat cgtcaactgg agcacttgtg
      961 gcactggaga agccggagat cgacttcccg gagggcaacc cgcccgccga cctggaggtc
     1021 gtcgacatag tcgagggtga cggccccgag gccaagcccg gccagaacgt cagcgtccac
     1081 tacgtgggcg tggcgttctc caccggggag gagttcgacg cctcctggaa ccgcggtcag
     1141 gcgttcgagt tcccgctcgg cgccggccgc gtcatcgcgg gctgggaccg gggcgtcgcc
     1201 gggatgaagg tcggcggccg gcgcaagctg gtcatcccgc cgcacctcgg ctacggcaac
     1261 cgcggcgcgg gcgcccgcat caagccgggc gagacgctca tcttcgtcgt ggatctcctc
     1321 ggcgtgcgct gagcgcgatc gggtcgaagc ggccgccgtg cccgggcacg gcggccgctt
     1381 cgcgtcccgg cccctgttct ggcgcgcatg ggtggggaaa tgtcggcgac gtgcggcaac
     1441 atagggagtg tgctgctcat cgaggttgtc cgggtttctg aggcggtgac gcgaaccccc
     1501 gccaggctgg gcaagatcgg ccacctggcc gagctgctcg gccgggtcgg ccccgacgag
     1561 gccgagatcg ccatctccta cctctcaggc gagctccccc agcggcaggt cggcgtcggc
     1621 tggcgcaccc tcgaggacct cccccagccg aaactcgccg ccaccgccac cctcaccacc
     1681 gtcgacgcgc tgctcagcaa gatcaaggcg gtgtccgggc aggggtcgca ggccgcgcgc
     1741 aaggcgctgg tgtccgaact gttcgccggg ctgaccagcc aggagcagca gttcatgcgc
     1801 cggctgctgc acggcgagct gcgccagggc gccctcgacg gcgtcatgat cgaagcggtg
     1861 gcgaaggcgt cgggagcgcc gtcccccgac gtccgccggg cgctgacgct gcgcggctgg
     1921 ctgccggccg tcggcgccgc cgccctcgcc ggcggcgcgt ccgcgctgcg ggagttcaag
     1981 ctggaagtgg ggcgggccgt cgcgcccatg ctcgcctcca gcgcccccaa cgtcgccgcc
     2041 gcgctgcaga aggccggcac gcccgccgcg ctcgaatgga agatcgacgg catccgggtg
     2101 cagggccacc gctccggctc cgacgtacgc gtcttcaccc gcaccctcga cgacatcacc
     2161 cctcaggtgc ccgagctggc cgaggcgctg ctgcgcctgc cgtccgacga cctcgtcctc
     2221 gacggcgagg tcatcgccct gcgccccgac ggccgccccc acccgttcca ggtcaccgca
     2281 ggccgggcga gcagcaggac caacgtcgcc gccctgcgcg aggacacccc gctcaccgtg
     2341 ttcttcttcg acgcgctccg cgtcgacggc accgacctgc tcgacctgcc ctacaccgac
     2401 cggcaggagg tcctcgcccg cacggtgccc gccgagctgc tcaccccccg gctcgtcacc
     2461 gacgacgtcc gcgcggccga gcacttcttc gccgaggccg tcagggcagg ccacgaaggg
     2521 ctggtcgtca agtcgatggc cgcgccgtac gcggcggggc ggcgcggcgc cgggtgggtc
     2581 aaggtcaagc cccggcacac gctcgacctc gtggtgctcg ccgccgaatg gggccacggg
     2641 cggcgcgagg gcaagctgtc gaacctgcac ctcggcgccc gcgaccccgg cggcggctac
     2701 gtcatgctgg gcaagacctt caagggcctc acggacgagc tgctggcctg gcagaccacc
     2761 cggttcctcg aactggccga gggccccacc gacggctgga ccgtacagct gcggcccgaa
     2821 ctggtcgtcg agatcgcctt cgacggggtg cagcgctcgc cccgctaccc gggcggcatg
     2881 gccctgcgct tcgcccgcgt ccttcgctac cgcccggaca agcgccccga ccaggccgac
     2941 acggtcgaca ccgtgcgctc cctgatgctc tgacctcgca ccggccgttc cccggcatcc
     3001 ggctcagcgg caagcgggga accccgtgga ctgctcggcg cacccggtgg ggtgtgccgg
     3061 ccgtcagctg cagcggttct cggacaaccg ggtcatcatt gttccccgct ccggccacgc
     3121 ctgccagtag atcgtcccgc acctgaagtt ctgatgagct tcgttgccca cccggagctc
     3181 agccgacgtc gggtatccca gccatccccg ctcgcaccct tcctggcacc atctcgcgcc
     3241 gatgtccccc cacaccggcc acgcgcccgt ccgcgggtgc cagtagatcg tgccgttctt
     3301 gaactgagtg cggcgaccca ccccgtccgg gttggcgagc tcttcggtga gggggcagcc
     3361 gagctgcccg gtggggccgc ccatctgcac gtagcgctcc tcgatggcgc ccaccacttt
     3421 gagaccgcag taggtatgcg ggtcgtcggc gtgtgcgggc gtggccgccg ccgcgatcag
     3481 cgcgccgacg gtgagggtga gcgcgctcaa gctcgcggcg atcctgtcgc gtcgcggcct
     3541 ggcgctcgtg gcggtggtca tgcgtgcacc gtcctttcct gccccctgcg ggggcggcgg
     3601 gcagcgggtg cgtggtgccc tctgcggttc ctggtgatgc gtactttggc ggccccggac
     3661 gatcgtcaca agcgggggtc cggaacgtcc acataagcca gtcggccgaa tgcgacgtaa
     3721 gcgcgggttc gccctacctt gccatcttga tctcgcgggt cccggtgctg cccggccgcg
     3781 caccggcgac aacacgcatt ccggagctca aggagctcct ggccgaagag ggcgcgaaga
     3841 tcgagcgcat ccagaacgcg atgaaggacg agacgggcgt cgaccacgtc gtcacggcct
     3901 gacccatcgc cgcttcgccc accacgggcc ggcgctcatc acggcagcac ccaggacggc
     3961 aggcgcatcg gcgagctctc cctggctcgc gcccggcgca ggtgtcgcgg tgccgcgctc
     4021 ccacggcccg cgtacggcgc aggtgtcgcg gtgccccccc atcgccccgt gcccggcaca
     4081 tgcgcggtgc cacgccccca tcgcccgcgc ccagcacatg cgtggtgccg ccccccatcg
     4141 cccgcgcccg gcgcacgcgc gggggttcgc gctcctatgg cccgcgccgg gcgcgcgcgg
     4201 ggctccgtcc tgcggcgtcc acccgcccga actggtgatt tgttggatct tgtcctgata
     4261 gtgacatatg tcacttaatg tccgattaga ttgcctttgc ctggtgttgg tggcgtaagt
     4321 tcttccacac cccgcgacgt tccccctggt cgcgggcggg atcggccgcc gtgtgcctcc
     4381 cccctccccg gtccggcctt tcccttcctc atcccctagc taggaccgtg gtttaccttg
     4441 ggccagcatt cgcgccaccc gtccccccag ccgttccccg acgaccgcga aggcggtcag
     4501 aacccccacg acgccaagcc cgcccccagc aggcgtcggt ggaccgccgc cgtggcggcc
     4561 ggcgccgccg tcgtcgccgc cgtctccacg accgcctggg cggtcacggc cgacgacgcc
     4621 cccacctccg cggcggccgt gaacctcccc ccgaaccccg ccgccccggc gtcctcctcg
     4681 ccgaagcccg gcgtctcctc ccccgcgccg tcccccgccg cgccgtcctc cgtcgccgag
     4741 gccgctcagc agggcaaccc cgacccgtcc ccctcggcgg cccccaagcc tcccgccgga
     4801 gcggagccga agtcctcggc ctcccccagg ccgtcgcacc gcaggatcga gaccgtcgcc
     4861 cgtcccaaga agaagacggt cgcggcgaag acccaggccc gcgtggtctc ctccgggagc
     4921 tgcggcgcct cctactacga cgagccgcag atgacggcga gcggcgagcg tttcgacccg
     4981 tccgcgatga ccgcggcgca caagaccctc cccctgggca gcagggtccg cgtcatcaac
     5041 ccgaacagcg gcgcttcggt gatcgtccgc atcaacgacc gcggcccgta cgtcggcgga
     5101 cgctgcctgg acctgtccag ggccgccttc tccgcgatcg ggagcgtcgg cgcgggagtc
     5161 atgacggtca agtaccaggt gctggcccgc tgaggcacgg caggcccgcc gccggaccgg
     5221 gcgggctctg tcgggcttcg gaagagcagc cgccgccgga acgccagaca tacccgattc
     5281 gagcggacac cccccgattt atcccgataa atgaattccc ggcgaaagcc ccgaatcgga
     5341 tgaccctgaa tacacccccc atattcaggg tcgtcccgag ggactacttc accaggcgaa
     5401 ccgtcaacgg gtagcggaag gcgccctcgc tcagggccga cacgccgccc acgatggaca
     5461 gcacgatccc cgcgacccag atcaccggca gcagcacgat gcccacgacg gtgaacggca
     5521 gcaggatcga cgccccgagc agggtcagct ggaagttcag cgcctcgacc gcgtggcgcc
     5581 ggatgtacgg cgacgtcttg ccgcccgtga gcatgagcag cagcggaccc agcaagggga
     5641 acccgaccac cgcgaggccg tgcgcgagcg cgccgcccag gcgctcgttg ctctccgggg
     5701 cgggctccgc acggaacgcg ggcgaaggcg acgcgaagtg cggcacggcg ttggagccgt
     5761 acagctcggt catgatgggc atcaggtcgc cgtgggtgcg cgccgtcatg gcccgctcca
     5821 ggcggtcgtc gaactccagc ttgtcgaacc ggccctcggc gtacgccgcc ttgacgtgct
     5881 cgacgacgtg ctcgcggtcc tggtgagtga cgcgcaggtg agccggcggc acatgtccct
     5941 gcccccaggg ttcgggtacg ggtaccccag ccatcgcagc catgcctctc cttcggttcc
     6001 ggcgttcagt cacatactgc gtcttccagg ccgctcctgc catccggaga atcccggagg
     6061 cgtcccctag atcgcccccg acgcgaagct tccagacggt ataaaaagga atcatgagat
     6121 ggcgagaccg ctacggcatt cgccggctac gcggtgcgaa ggtcgcgaag ttcgaccgtg
     6181 aggcgacgga tgcggatatc gaagcgctca tcgccttcgc ccgttcccgc cggggagtgg
     6241 agttctacgt cgagccggag accttcgcca cggacaccac cgccgtggcc gtcgccgacg
     6301 acggcgagtg gaccagacgc agggtcggct cgccgggcgt gatccacaag gtcgcccgcg
     6361 acctcgcatt acccgtgtac gacgtccagc tcaccggcta cccgccccgc atgcgcgcct
     6421 acaacgaacg ccgccgccgc gaacaggacc tcccctgacg cgctcccccg cctggaaagc
     6481 cggggatcga gcccgtgccg cgtgcgcggc gcctctgtgg cttcctgttt ctccgggtcc
     6541 tgccctcccc cgctagacgg cgcgtccctc cgcaggcgtt caggctgtcc gcccgtccgg
     6601 cggccggaag ggcccgaagc ctgagccggc gccccggcca tccggccgga ctctgacgcc
     6661 gggtcgccga gcaggggcga cgcccgcctc cgcggaaccg ggcggccgat cgccctgttg
     6721 accaccgccg gctcgttgat cgagcccgtt ccgcccagcc ggcctccgcg cctctccgcc
     6781 gcaccgcacc gcgcgcgccc gcttcttcgc gcccgcttct tcgcgtccgc ttccttcatg
     6841 gcgaatcgcc gccggagtcc gtcacacgcg tacgaggggc ggagccacac ccggccccgc
     6901 ccctagtccg gtcaccctcg gggagtgacc gtgcgcgcct tgccggagcc ggcgtcacca
     6961 ccggccgagc cgcgacggat gtcctgtcag gcgaaggaca tcttccccga ccccgtcagc
     7021 tgggtgaagc ccgacggagc cgtgcagtca cgcaggtcgg acgtcatggt ggcgctcccg
     7081 ctgaagtgcc gacccttcag ccgtcccgag acgacgtcgc cctgcagcag gctgtcgtgc
     7141 agggaggcgg cgcctttgtg ctcggcggtg agctgcgagg tgcccacgac ctggccctgc
     7201 gcgtcacgcc aggtgacggt gccggtggcg ctcaggtcgg cgacgccgcg gcagttggcg
     7261 gtggccgtgc cgctgacctc cagcctcccg gaggcgatgt cggcgacctt gccgttgggc
     7321 gaggtgcagc cttcgaggag gacgaccccc tgccccttga cctgctgcgc cgccgcgtcg
     7381 cgcagcgccg gggtgaaggc gatggggttc ttgggggcgg tgcgcatggt gcaggtcagc
     7441 gcggcctcct cgcggacggc agcggccgac gccgccttgc ccgaagccgc ctggctcgac
     7501 gcccccgcgg cctgcgccgc ctgggcggag cccgcgaacg ccagcagcgg cgccgcgaga
     7561 ccggcggtcg cggcggcgag ggcgagagcc cgggtgcggc tgagacgtga ctgacggatc
     7621 atccgtcctc cgatcatgac tacgatgggt catctcttgg cgactctttg taacacactt
     7681 tcgctgatct tcaacgggag gcggccatgt ccgtgtcatc gcgtccgtcc gccgaggggc
     7741 gcccggtcgc gccgggcccg ccggccggcc cgggccgccg tcccctctgg tggcggctcg
     7801 gccacctggc ggcgcgccgc caccgcgccg tcctcacggt gtgggcgatg ctgctggcag
     7861 ggtcggccgt cctgatcccg ggcctgctgg aacgcgccat cgcccccgcc gtgcgggtcg
     7921 aggggagcgc ctcgctcacc ggcgcccggc tgctggagca gggctttccg cagctgggcg
     7981 gcgaacagat gatgatgatc ttcgcgtccg ccaccctgtc cgacgccgac gagccgtacc
     8041 agcgtgctct ccacgacgcc ctccgcgcgg tgtcggccca gccgcaggtg ggcggcacgc
     8101 agctgctgcc cgtcgtgccg gggcaggacc accggcacgc gtacgcgatc gtcggggtca
     8161 acggcgacca gcgcgcccgg caggccgcgc tgccgccgct gctcggcgcc gccaaggagg
     8221 ccgcgagccg ggcgtcgggc gggcgcgtgg acgtccacct cgtgggcgag agcgccctgc
     8281 tggccgaggc caagcacacc gacctcgccg acctgcgccg cgccgaactg ctggccgtcc
     8341 ccctgtccct gctggtgctg ctggcggggc tcgcgtccgg cggagccgca ctggcggtcc
     8401 tcgccgtcgc cgggacggtc acggtgaccg cgctcggcct gctggcggcc gcgagcctgc
     8461 tcggcgtgcc ggtcaacacg ttcatgctgg ccgtggcggc cacggtaggg ctcgcgctcg
     8521 ggctggacta cgcgctgctc atcctcgtcc ggtaccggca gtcccgggcc gccgggcacg
     8581 accggcacca ggccgcggcc gtcgccgtca gcaccgccgg acgcaccgcc gcctggtgcg
     8641 ccgtgggggt cgcgctgacg gcggccgcgc tgctggtcgt gcgcacctcc atgatccgga
     8701 ccatgggcgc ggcggtgagc gtgtcggccc tggtcgccgc gctggccgcc gtgacgctgc
     8761 ttcccgccgt cctcgtgacc gccgaccgcc ggctcctccg ccggcaccgg ctccgcctcc
     8821 cggccttcct cagccgtcgc gtacgcgctc tcctcgaccg ccccgcacgc ccctcggcct
     8881 cgaccggccg tcctcctgac gggcgacgtc gtgaggacga gcacgggtgg ggccggtggg
     8941 cgcggcacct catgcgtcac cccgtcgcgt acaccctggc ctgcgcgggc ctcctcctcg
     9001 cggcggccgc gccgctcgcg ggggtgcgcc tggcgttcga cctggaccgc gcctccatcg
     9061 ccggcaccga cttcgggcgt ggcctgacgg cgatggaagg cgacgggatc tcctcgtcgg
     9121 tggccgtggc cctgccgcat cccgcgggcg cgccgcccgt cgacacagcg gcactggtca
     9181 ccaccctcaa gcaggatccc cgggtgtcct tctgcacctc gctcgacaac ggccgggacc
     9241 tgaccgtcgt catcgtcatc atccgcacgc acatcgacga ccccgccagc accgccatgg
     9301 cgcgggagat caccggccgg ctggtcccgg cgtcgatgcc accggatcag cgcgccttcg
     9361 tgaccggacc caacgtgatc ttctccgacc tcatggacga gaccacctcc cagctcggga
     9421 cggtgatccc gctggtgctg ggctgctcgc tggtcttcct cctggtgacc ttccgcagcg
     9481 tcctcctgcc gctcaaggcc gtcctgatga acctgctggc cgtcaccgcc gcgttcgggc
     9541 tgctgaccct ggccacccgc cacctgccgc acctggtcgg cacccacgtc aacacgctgg
     9601 tgccgctgct ggccttcacg ctggtgttcg gcctgtcgat cgactacgag atcttcctca
     9661 tccaccgcat cgccgagcac taccacgccg gaggcgacaa caccgccgcc gtcgttcacg
     9721 gcctgcgcca caccgcccgt cccatcacgg tggccgccgc cgtgatggtc gccaccttcg
     9781 ccgccctgct caccgcccac cgccaccacc tcgtccagct gggcctcgcc gtcgccacgg
     9841 cgatcaccct ggacgcgacg gtcatcaggc tggccctggt cccggccctg atgcgcatcc
     9901 tgggcgcccg caactggtgg ctcccggccc ctctggcccg cctcctcccc actccccgga
     9961 ccactccgcc gccgcccccg cactgagccg gggaggaggg tcattcgtcc tggtggcgtt
    10021 cggcggcgta gaggccgagg gcgcggatca tgaccgtgtg gtgattgacg gggaggaggc
    10081 gctgcagggg tagccatgcc tcgtcgacgg cgtggcgggc gtcggccagg gcggcggccg
    10141 tggcgccgca gcccaccagc gtctcggcca cctccgccgc ggccgcctgg ccggctcctc
    10201 cgcagcggac gatctcccag atctcgcgca gccgcgcctg gggcagcagc gtgacggcgc
    10261 aggccagggg gtaggtgacc ttgccttcgc ggatgtcctc gcccgggacc ctcgcgaccc
    10321 gggcgcccgg gtcgcctgct cgggccagca cggcgagaag gtccgcgacg tcgtcactga
    10381 tctggtaggc cagcccgatg gtctcgaagt acgagctgat cgccgtcagc acctcgccgt
    10441 cggcccccgc gaggacggcg ccgaactcgc cgacgccgcg taccacgccg ccggtcttga
    10501 gccggtgcgt ggtgcgcacc cgttccagca cggcggcggc gtctcccgag gccaccgcct
    10561 cctccatggc gtcgtggtgg ccgaggatgt cgagcgcctg accggcgtga ctgcggcgca
    10621 tgccgtcgag gtacacctgg tacagccgca gccgccgctc ggggtcgtcg ggcagcaggt
    10681 gccgtgcgac caggtcgaag acgaggtagg cgtgcgtgcc ggtgttgatg gcggtggcct
    10741 gcccgaacac ccggtggacg gcgggccggc cgcggcgcat cggggcgttg tcctcgacgt
    10801 cgtcgacgat gaggctggcg gtgtgcatca gctcggcgag cgcggccagc gcgcggtact
    10861 gctggctgtc gacgccctgc atctccatgc cggcgatcgc ggcgtagctg cgccagcctc
    10921 tgcccatcgc gtcggccagg tgccgtaccg gcgcgacgag cgcgcggtgc agcggctccg
    10981 cgacgacgtc caccggccag gccgggcgag gggcgagtcc ggccaggacc gcgacggcac
    11041 caggttcggg gctgtcgggg tacaggcgta cgacctcggc gtgagtgacc tcgcgcaggc
    11101 gctcgatgcg gtgttcgagg tcgcggatgc ggggggccgg ctcgacctcc agccagcctt
    11161 cgccgcgcac cggccggccg tgcagctctc cctcggcggt gacggcggcc tccagcgagg
    11221 cgcccaggcc gaggaggacc ggccgttcct gctcctggaa gcaggcggac acccgcagcg
    11281 ccaggcccgc ccgcggggcg tcgacacgcc aggtcgtggg gtaggagttc agcgtcctga
    11341 tcgacgtcca tggcgcgccg gcgtcgagac gggccggcac gtcgtggtgt gcgccgtcgg
    11401 gggccaccag cgtcacggac ggcgggcggc ccgctgctgc tccgccggcg gggtcgtgga
    11461 cggcggactg gcaggccacg acgtcccagc cgtcctccag atgcaggacg atccgggtgt
    11521 gcgcccggtc ggccggcggg gacgcggcgt cctgcgggag ttcgccggcg ccgtggaccc
    11581 gctggtacga gcccacgccc gtcatgcgga ccggcggctg ccccggcctg gtccatacgg
    11641 cgtcggccgc caggcgggac acgaggaagg cttcgcgcgc ctcgtcgtca ccgtcgaccg
    11701 cgtccccgac gggcggcacc gcgagctccc gggcgggttc tccgccggac tcggtgatgg
    11761 cgggcttgag cgggcgcagg cgcaggtccc acgtctcgtg gtcgtcgcgc aggaccaggt
    11821 ggtagccgcc gtcgtccgcc accgacaggt cggcgacgcc gccgaagtcg aggcgcagcc
    11881 ggtcggacgc cagggtgacg gggccgggca gcagccggtc cggggcgatc ggccggccgc
    11941 ccgcgcacgc ctcccgcacc gactcggcga tggagcggtc ccatccccgg gagacgtcga
    12001 gggaggtcag ctccaccccg ccggcgtccc gccaggcgca cgcctggtac gtcctgctcc
    12061 tcggcatgct gtgggtccag ccgcagccgt gggagagcag cacgtcgccg tcggacctgg
    12121 gggtgcggcg ggcgaggaag gccaccatga gcgcgtgctc ctccccgcgc gcgtcacgca
    12181 ggttcaccgt gaaccgccac gactcgtgac cgttgacagt ggaccgccac gactcgtgac
    12241 cgaggccggg acgcggcacg tcctgcgtgc ctcgccgccc ggacgccggc aggccggagg
    12301 aggcggggcc gccggtggac ggcgccgggg cgggatcgcc ggacgcgggc cgtacgcccg
    12361 gcagcatgat ctccctggtc tcgggggtcg cctcaagcgc cactcgtcca ctccccttcc
    12421 tcggcgacgt tctgcgatcg gttgatcgcg aactgtcatg atggtggatg gggtgccacg
    12481 acggccaccg aatcggaggg ttcatgcgat cccgtacccg atgccggcgt gccgtcaggg
    12541 caggcgacca cgtaccgtca ctctttgttc ggtttcgcag acatatccgg cccggccgaa
    12601 tacggtggtc ccttgacgat cggccaagcc cgtcagcctt ccccggagct tccacatgcg
    12661 taccgcagcg gcaattctgt ccttcgtcct cgccgtcacc ttcctgcccg ccgggccggc
    12721 cgcggcagtg gtgtccgccg cgtcgctgcc gggcggcaag accaccttcg tcgtctcaca
    12781 gggccacctg aaggcggcct cgcagcagaa ctgggtacgc ctgggcgact accgcttcgc
    12841 ggcgaacggc acggtgagcg cggccatgta cctgtggtgg cagcgccggc cccaggccag
    12901 gcagcgcact ggcaccgtcc ccgaccagag ctgcaccacc aaggcgggcg gcaagcagtc
    12961 gcggcctcgc acctgtgagg tgctgaccgc cgggggcttc accggcgccc ccgacgagag
    13021 ccgcaccggc acgtacacca tgtcaggaaa cgtgctcacc atccggtgga agatcgccca
    13081 ggcgtggacg gagcagtggt acgtgcggac ctcgcctgac ggcaagctcg cccgcctcga
    13141 cctcaagcag agcacgctcg ccacgcacgg ctacggctac ggcagcaacg ccgcgatcag
    13201 cacccgccgc gcgatgagct cggtgaaggc gttcccccgc gcgctcaggc aggacctgac
    13261 gagctgggcg ggcggcaagc tcgtcaccgc cggcaaccag ccgttcggcc tgtccgcctt
    13321 ccgcgcctgc tccgccacca cctcgtgcct gacctacctg cagccgtcct cgaacaccgc
    13381 gtgccagaag gagggcggct gccccaagta cggcggcgga acgcgtccca acgtcacctc
    13441 catccagtac tacctcacga tgatctccaa gtccgaccgc cgtgacacgc tgtggcactg
    13501 gtgcacctgc ctggcgatgg aacgcggcga gttctgctac accggcaact cccacgtcaa
    13561 accgctgatg cagatcatcg acgacacggg ggcgttccgg ggctgggtcg gcgcggaggc
    13621 gtccttctcg accggctccc gggcgacgga catgctggcg gtgctccgca tctccgactt
    13681 ccgctgaccg gctcctacgt gctctcccgg gcgcccgcgg cgggacggcc cgccctccgg
    13741 tctgcctcgg agcggcgtcc cttccgcgcc gccaggacga tgagcgcccc ggcgatcgtc
    13801 ccggcgaaga acggggacgg cacgagaagg acgccgccca gggcgcacca tgccgcgagg
    13861 ccccagccga tcgcggcggg cacggccacg ccgcgtccgg cgaggtgcca ggtcaggcag
    13921 cccaacagga tcagggctac ggcgaagctt cccgggcccg cccagaaggt gacctcgttc
    13981 tgaagggaag ccggcgtctg aacggccccc cggtccgaga gttcgagcgg gacggccgcc
    14041 cacatccccc ggtcaaccca gcgggcgacg tcctcccggg ccatgaccgc cagcagggac
    14101 aggtgccccg cccccagcac gatcatgatg ccgctcgccc agcggagcat cagcttgccg
    14161 gacttcatcg tggcgtccct ccccggtgct cggcctccag gcggccgcgt tcgagccagg
    14221 cccgttccca ccgcccggtc agcgccgggt agacgacgag gtaccggaag ggcgcgatgg
    14281 cggtcatgta gagccggccg aacagtccgt tgtgcttgac gaggacggcc atccgcagct
    14341 cgtggtcgcc gttcgttcct tggacccagc cgagatgcat gacggtgtgc acggtcctgt
    14401 tcgccagctc gcgagcggcc tccatgtcga gttcgtagac cgctttgagg ggcatgccct
    14461 cgtcgtcagg gccgcgggga gcgtcccgga tgtcaccggg caggcggtcg cggagcgagg
    14521 cgacccgcga gccgacgccc gccgagggtt cgtcccagcc gagcaacgcg ccgagtcgcc
    14581 agcggacggc gaacaggaac ctcgccggcc agggttgctt cgccaatccg ccgaaggctc
    14641 gcatcgccgc cagcatcgtg gggaagtcgc cgggcccggc tccgggggtg cggaacgccc
    14701 acacgtcctc gaccgagaag tccctcgtga actcgtgaac gcgccacggg cgggaggtga
    14761 acgccgtctt cggcagcctc acgagaggcc cttctcggcc atcatcgcca tcagcgtcag
    14821 ctggtccagg tggggcgtgc tctcggggtc gagctcccgg tagcggcggt gcaggttgac
    14881 caggatccgc tcggagtcca gccaggtggc gtactcggcc aggtccaccg cctgggccgc
    14941 ctcggcgtac gacaggccgc gggcgtaggc ggcgtcggcc tgctcgacca cgtgggcgag
    15001 gtagccgcgc accgcgcgga tcccgtcggg gtcggtgacg gggccgtggc cggggacgat
    15061 cgtgtgggcg ccggtggcga tcatccggtc gcaggcggcg atccagttgg cgatcgggcc
    15121 gctccacacg atcggcgtgc agccgacgaa cagcaggtcg cccgcgaaga gcacgcccgc
    15181 gtccggcacg tggacgaccg tgtcggccgc ggtgtgggcg gggccgaggt tcatcaggcg
    15241 cacctcgcgg ccgccgatgt cgagggtgag ttccttttcg taggtcaggt cgggcagccg
    15301 caggcggatg ccgctgaagt cgaaggcgcc gaagcgttcg cggaagtagg aggtggcggg
    15361 gccgaggtcc aacacctggg tggcggtcag catctcgggc ggcatctcgt gccgcatctc
    15421 ggtgcgggtg gcctcggcgg cgacgatcgt gacgtgctcg cccagcagct ggttgccgtg
    15481 ggtgtggtcg ccgttggagt gggtgacagc ggcgtgcgtg agcgggcgcc gatcggtgat
    15541 ctcgcgcatg gcgtcgagca tctcggccgt cagcggcagg tcgaacaggg tgtccacgag
    15601 cagggaggcg tcctcgcccg cgacgagtcc cgcgttgctc aagccgtacc cgccgtcggg
    15661 caggagccag gcccacacgc ccgcgccgac ctcgtgcagg ccgcgcgtgt agggcaggct
    15721 cgacggggcg cggttcacgc gggggcgcgg cggacggcgg tccgggttct tccggggcgt
    15781 cagcgggtgc ggcgcggccg acgcgcggac ggtctggcgg gtacgcccca gcccttcgac
    15841 ggtcagctcg acgacgtcgc cgtcccgcaa ccagccgggg aacgcggccg gatcggcgag
    15901 ggacaggtgc tcgacgaggc agcagccggg caccgtgccc gagccgaaca cgtcacccgg
    15961 caccaggtcc acgccgcggg aggcgtagga gatgacctcg ccgaagctcc agtccatggc
    16021 gtcggtacac cccgagccga tgacccggcc gttgacggcg gcctcgacgc gcagggcgag
    16081 cctgtcgccg cggcggtagg gctccagctc gtccggggtg acgaggtacg ggccgagcgt
    16141 ggtggcggcg tccttgccct tggcctggcc gatcgccagc ggcgcctcgc gtagctgcag
    16201 gtctcgggcg gaccagtcgt tgtagacggt gtagccgacg atgcgttcct cggcctgttc
    16261 gggggtgagg tcccggccgc cccggccgat gaccgcggcg atctccagtt cgaagtcgaa
    16321 ccaggcgctc ccgggcgaga tcgtcacgtc gtcgtacggg ccgacgaccg tcgagggaca
    16381 ggcgaagtag aaggccggga tctcgtacca ggcgtccttg agggtgcgcg gctgcccggc
    16441 ggcctgctgg caggcgcgca tgtggtccag gaagcacagg gagtcgcgga tggagggcgg
    16501 acgcgggatc ggcgcgcgca gcgtggcctc ggccagcgga accgtcggcg ccgccgacgc
    16561 cagcgccgcc tccccgacgg cacgcagctc ttccgcgccg cggccgatga gctcgatcag
    16621 gctgacgtcc ggggcgacgg gatggatgcg gtcctcaccg atcacgccga cgcggtcgcc
    16681 ggtgtccgtc gcgtaggtca cccaacgcat gagagcctcc cttggcttct gtgctgacca
    16741 acacaggcta tatcgctcag catttgctct gccatccggc atacctggtt tgatggtggg
    16801 catggccacg cgacgtatcc agagcagcga ggagagccgg cggctgctgg tgacggcggc
    16861 cgccgagctc ttcgccgaca ggggataccg gcagacgagc ttcatcgaga tcgccgacag
    16921 ggccggcatc agccgcggct ccatcccctg gcacttcggc aacaaactgg gcctgctgaa
    16981 agcggtgatc gacgaccagc tcgacgccgt gctcgccgcc gccgccccat ccgcgaacga
    17041 ccgctccggc gacccgttcg accaggtcat ggccttcatc cggctgcccg tcacccgcct
    17101 gttcatcacg ctgctcgccg aggccgtgga ggtcgactcc cccatccgcg agcactacgc
    17161 gcggctccac acggcgctgc gggacgcggc ccgggcccgg atctcagcgg aggcgctgcc
    17221 cccaggaacc acgcaggagg cgttcgcggt ggtgctggtc gggaccctga tcggcgtcca
    17281 cgcccagtgg cgcgtcgctc ccgacgcggt ggacctgcgg gccgtgcagg ccgcgctgcg
    17341 cgccctgctg ccagcgggcc tcatcgagat gtgacagccg gtggcacgta cccgaaggcc
    17401 ggatatcacc tcagccttgc catgacatgt caatatcggg ctatcatcgc tatatggcga
    17461 ttgataatga ggccggccgc tgcgtcagcg ccgacatcgc cgccggcatc tcccccgcgg
    17521 cggccttgtt ccactccctg gccgacgaga accggctgcg catcgtggcc aggctcgcgc
    17581 gcggcgaggc ccgggtcgtc gacctggtcg gcgagctcgg gctggcgcag tccacggtct
    17641 ccaagcacct ggcctgcctg cgcgactgcg acctggtcga ctaccgcgcc gaaggccgcc
    17701 agtccttcta ctccctgacc cgccccgagt tgatggatct gctcgcctcg gccgagcatc
    17761 tcctggccgc caccgggcac accgtggcgc tctgccccgt ccacggcacc cggcacggcg
    17821 gagccggcgc gcacgacgcg ctccaggccg aactcgacca cgacctcgaa cacctcgacc
    17881 agcaggcgga cgagatcgag gggaaggcgg tgtcatgacc gcgctcgacc tgcccgcccc
    17941 ggaccggcgc accgtactgc ggcgccgcat ccggctgctg gtcgcggcca ccatcaccta
    18001 caacgtcatc gaggcggtcg tggccctcac cgccggcgcc gccgcctcct ccgccgccct
    18061 gatcggcttc ggcctggact ccgtcgtgga ggtcgcctcc gcggcggccg tggcctggca
    18121 gttctccgcg accgatcacg agaggcggga gaagaccgcg ctgcgggtca tcgcggtctc
    18181 gttcttcgcg ctggccgcct acgtcacctt cgacgccgtc cgcgccctgc tgggcgtcgg
    18241 cgaggccggg ccttcaaccc ccggcctggt cctggccacc ctctcgctgg tgatcatgcc
    18301 gttcctgtcg tacgcccaac gccgtgccgg ccgcgaactc ggctccgcct ccgcggtcgc
    18361 cgactccaag cagaccctgc tgtgcaccta cctgtccggc gtgctgctgg tcgggctggc
    18421 gctcaacagc ctgttcggct ggtcctgggc cgacccgatc gccgccctgg tgatcgccgc
    18481 ggtcgcggtc aaggaaggcc gcgaagcctg gcgcggggac gcctgccgcg ccgtccccac
    18541 ctccacctcc ggcagcatca cgtccgagcc tgagggccgc gcggacggct gctgcgtcca
    18601 cgacacgcag aaggacaagc gatgatcggc cgtccgatgc ccgcgcgagt gcgggcctcc
    18661 taccgcgccg agatgcgcgc cgcgcgcacc gccgtcaccc ctgaggctcg ctggcggcat
    18721 ctggagcgcg cgcacatcat ctcccagccc tggccctggc cacacacccg caaccacctc
    18781 gcgatgttcg ccctggccgt ggcccagcgc gaccggcgtg aggcgttcgg ccaggtcatc
    18841 cggatcatcg tggccgcgcc cggcagcgcc ttgggccgct accccgaagg caacaccggc
    18901 cgcgccaccg tcggcctcac ccagccgatg cccgtgccgg acgacctggc cgcgctgctg
    18961 cgggccacct gaaacgggaa ggccgggctc acgcgcgcgt gtcctggaag gccccgcggc
    19021 actcggtcgg cgtcacgccg accgcgcggg tgaagtggtg ccggaggtcg cccgccgagc
    19081 ccagcccgcg gccagcgcga acgcgcccgt gcggagcgag accatgcggg cgtcgcgccc
    19141 gtgcgcggcc ctgagcgcgt ccggcaggtc cgggtccagg cgggcgtcac cctccacgta
    19201 gtcgcccggg agcgcgggga cgacgaccgt gtcggcgctc accagcgcgt cgagcccgta
    19261 cggcggcgtc agagcgaacc cgtggcgggg tgcggaccgg gccggcggcg gccgggcaca
    19321 gctcgtacca ggggtcggcg aggtcgggcc gctccaggcc gaacgtctcg cagatgatgg
    19381 acacctcgaa catcgggcat gccgtcgagc acggccagcg cgaccactgc agggctcttc
    19441 acgcccgcgt actgcctcgg agtgctcgcg gcgctgctgc tgttcgggcg gatctccgac
    19501 tcgtggggac ggcgtccggc catcctggcg gggctggccg ggctgctcgt ctcgctgggg
    19561 atgttcctga cggcgtccgg ggtgggccgg ctgttcgtcg cgcgcggcct gcagggcgtc
    19621 gccaccggcg tcgcgatcag cgccgcgggc gcggccctgc tcgacctgcg tcccgccgcc
    19681 gccgggctgc tcaacacgcc ggccagcggg ctcgggatgg gggtcggcgg gctgctcggc
    19741 gcggttctgg tcgagtacgc gcccgccccg ctcctgactc ccttcgtggt gctcgcggcg
    19801 gtgaacctcc tcctgctcgc cggggtctgg cggcggcccg agaccgtggg cgcccgggcc
    19861 gggttcagga tggcggcgcc gggggtgccg agggagatcc tgggatcgtt cgcgctgtcc
    19921 gggctcgggg tgacgtcgtc ctggtcgatc gtcgggctgt acctggccct ggtgcccgcg
    19981 ctggcgcccg ccctcatggg ctcggcgggg aaccttcccg gcgggctggc catcttcgtc
    20041 atgggcacgg ccgccgccct gagcagccgc cggcgcgccg atgcccagga cggcggccat
    20101 cagcacgacc gcggacaacc tcttggcgga tggcatgaga gctcctctcg gtgggaggag
    20161 ttgatagcgg gaacataggc ggccgcatgc cgaagatccg ttgaggaagt gctgagcatg
    20221 tgtcggcgcg cctgctgggg actgcccctc ggccatcccc ggcggaaggt ccacgggcag
    20281 acgcgcgaca tcgccaccgc gaccaccagc gccgagcccg cgcgcgagct cgtcaccgac
    20341 gaccgtcaca cacccgcccc ccggtacaga tccgagtcga cgggcggccg ccgcccactg
    20401 ccagggcgtg gctggaccga cgtcgtgctg tcggccagtt cctcggcagc tcggccaggc
    20461 tgtcgagctc ggtcatcacc aagctgactg accgagcggt ggagtgcacc ttcgccacgc
    20521 tccggcaccg caccaaggtc accaaagggc cgggtcccga gccgccggcc tggccatgac
    20581 cttcaacctc atcgagtcct cccagccccg ctggcgcgcg gtcaacgcac cccaccttgt
    20641 cgcgctcgtc cgcgccggag cccgcttcga aggaggcgcc ctcgtcgaac gcgagccggc
    20701 gaccgcagcc tgacgcgcgg tgctaaacag ggacacgtga gggaggcagc aatggtccaa
    20761 ggcacccgcg gcgagctcat cagtcggctg gccgaggcga tcaggtccgt cacggccgcg
    20821 cacccgctac gggtcgccat cgacgggccg cccgccgccg gaaagaccac gctggccgac
    20881 gaactcgccg tcgtcctgca cgcgcagggt cgcgacatca tccgcgcgac catcgatgac
    20941 ttcctcttcc cccgcgcaca acgctaccga cgcggccgat actcggccga aggctgctac
    21001 ttcgacgccc acgaccacgc cgcgctgtgc cgggtcctgc tcgatccgct gggcgcgggg
    21061 ggagaccgaa ggttccagca cgcggtctac gacagagaca cggacacccc atgctccccg
    21121 ccggccacga ccgccccagc agatgccgtc ctgctcttcg acggcgtctt cctcctgcgc
    21181 ccagaactca tcgaccggtg ggacctgcgc atcttcgtgt ccgtcccatt cgagcagacg
    21241 gtagatcgcg ctcgggaccg aagcacagca ctggccggat ccaccgccga caccgccgaa
    21301 atcgaacggt cctggcacaa ccgatatatc ccctcccaac agctctactt cgccacagcc
    21361 cgcccaacag aacacgccga catcatcgtg tacaacgatc agctccaacg gccgacctgg
    21421 gaagtccgac cacactcatc gatacacaag atctgacgat tgctcggttc tcggggcagg
    21481 ccgcgtcagc ctgccatcgg gctgtcgccc tggccgaagg ccagtcttgg tgtgacgcat
    21541 ggacacctct acggccggtt tcgggaagac ctatgcggta gcgaaccaaa agggcggcgt
    21601 gggaaaggtc gccaccacga tcgaccttgg aggtgtgctc gcggagcaag acgatcccgt
    21661 tctgatccag gtccagtcag cggctcgtga gtggtcaagc gaaaggtctc ctggccggcc
    21721 ggccgtcgcc gatggcaccg ccgctacgag cgccgggccg accgctttga gccctccctc
    21781 gccatcgcca gcacttttag cccggacgac cgcgtcaggc cattcgtcgc catcgccacc
    21841 gccctcatgc gctgccgccg gctgaccaga tgagacgatg tccaaggaga tgggcatgaa
    21901 cgcgcacacc agctcaatcc tccgcggccg gggccaaacg gctctacacc gagggcgtcg
    21961 gttggaaggc caggaacgac tgcggcgtct cgctcccacg accgcgtctc gcgccacagc
    22021 cacgtctcgt catcctgacc gcgagccagc tcgacggtgg gatgccttgg tcccttggcg
    22081 ttgacgggct cacccggatg gctctggcga cccggtgaag aaggattagg agcgcagcct
    22141 cagggggtcg tcgcggcccg ctctgagtcg ctgcggagga cgcagaactc gttgccctcc
    22201 gggtcggcga gaacggccca gccggtgccg tcggggttgc ggcggtcggc gacgaagatc
    22261 gcgcccagcc cgagcagccg ctccacctcc gcttcgcgcg aggtctccgg acgcaggcag
    22321 aggtggaatc ggttcttgac cgttttgggc tccggcacct ggttgaagta cagcatcggc
    22381 ccctgcggca gcggaacctg cgt
//
