LOCUS       NZ_BBZG01000003        21065 bp    DNA     linear   CON 12-AUG-2024
DEFINITION  Nonomuraea pusilla strain NBRC 110462, whole genome shotgun
            sequence.
ACCESSION   NZ_BBZG01000003
VERSION     NZ_BBZG01000003.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Nonomuraea pusilla
  ORGANISM  Nonomuraea pusilla
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1
  AUTHORS   Komaki,H., Ichikawa,N., Hosoyama,A., Fujita,N. and Igarashi,Y.
  TITLE     Draft Genome Sequence of Nonomuraea sp. TP-A0861, a Producer of
            Myxochelin A
  JOURNAL   Genome Announc 3 (6), e01430-15 (2015)
   PUBMED   26659677
  REMARK    DOI:10.1128/genomeA.01430-15 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1040125)
  AUTHORS   Hosoyama,A., Kimura,A., Ichikawa,N. and Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2015) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, Biological
            Resource Center (NBRC); 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.8
            Genome Coverage                   :: 107x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001417755.1-RS_2024_08_12
            Annotation Date                   :: 08/12/2024 01:46:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,307
            CDSs (total)                      :: 8,242
            Genes (coding)                    :: 8,159
            CDSs (with protein)               :: 8,159
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1 (5S, 16S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 21 of 83
            Pseudo Genes (incomplete)         :: 72 of 83
            Pseudo Genes (internal stop)      :: 5 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:25:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 626592
            Orig. end                         :: 647657
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBZG01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21065
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="3"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21065
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21065
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11065](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11065
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     misc_feature    complement(636..649)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.46"
                     /tool="antismash"
     gene            687..1064
                     /locus_tag="ASC57_RS26640"
     CDS             687..1064
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC57_RS26640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_055505950.1"
                     /transl_table=11
                     /translation="MTERYLGVLGIGEALGVSRHAVHKWRSRHPGGSGHPFPEPDVEID
                     GTPGWRPDRLAEIIRWRDGLPGRGAGGGRPTAARQEYLKEAAARGMDREEALRALATLG
                     EEFPEMTEPEICAWLLGHWRG"
     gene            1117..2301
                     /locus_tag="ASC57_RS26645"
     CDS             1117..2301
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541432.1"
                     /locus_tag="ASC57_RS26645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_055505951.1"
                     /transl_table=11
                     /translation="MPATRGETAPGFEAVRETFEAHLAGEPEAGAAVAAYLHGRKVVDL
                     WGGVADPATGRPWERDTLQVVFSTTKGVTAACAHLLAERGELDLDAPVAAYWPEFAANG
                     KDRVPVRWLLTHQAGLPAIDRPISPAQALAWEPMVTALAVQRPLWEPGTDHGYHAHTYG
                     WLVGEVVRRVSGRSLGRYLAQEIAAPLGLDLWIGLPAAELPRVSRLVTDPGDPGALAGI
                     DPDALPEPARELLRAYTDPTSLTMRAMTVVTPLLDHDDPREQVAELPATNGVCTARALA
                     RFYAALIGEVDGRRVLAPGTLAAATAEQVSGVDRVLRTPVRIGTGFGLPTPDAFWYSPT
                     AFGFPGYGGSIGFADPASGLAFAYVTNHLKPNTPDPRAAALLDAVRSALAPSPR"
     gene            2591..3751
                     /locus_tag="ASC57_RS41795"
     CDS             2591..3751
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016143.4"
                     /locus_tag="ASC57_RS41795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="neutral zinc metallopeptidase"
                     /protein_id="WP_236714952.1"
                     /transl_table=11
                     /translation="MPIPLPPIPLPPASLPPDSLPPASLPPDSLPPASLPPDSLPPASL
                     PPVSPPAPFATRVPASPPGRLSPSARARPVRGGRGGGPAGALPGGAVACLVAACLVAAV
                     PSGAAAATPVATTATATGTAAVASTAAGTSTAAGTTTTAVGPPSRSAVGPASGSASGPG
                     GEFSGTGRLSRGSCHEPPLVTGGIPRAKEYLEAVVACMNRSWGGHFSRAREAFARPAVR
                     FYDEPVGTVCGVPWPSDAAAFYCTNRRTLVFPLSGAWIENRTDLYPFKVAAHEYGHHLQ
                     SLTGVRRRYEARLRSQPSRQDELGRRYELQADCLSGVFLGSVRGSLGRGERDWDALLDA
                     VRASGDEGGYRSHGKGATRVAWLKRGLGSRSPAACDTWSAPASQVG"
     gene            complement(3957..6725)
                     /gene="acnA"
                     /locus_tag="ASC57_RS26655"
     CDS             complement(3957..6725)
                     /EC_number="4.2.1.3"
                     /GO_function="GO:0003994 - aconitate hydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="acnA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019608289.1"
                     /locus_tag="ASC57_RS26655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aconitate hydratase AcnA"
                     /protein_id="WP_055505953.1"
                     /transl_table=11
                     /translation="MSANSFGSRDTLRVGDASYEIFRLDAVEGAARLPYSLKILLENLL
                     RTEDGANITADHIRALAGWDPNATPSVEIQFTPARVIMQDFTGVPCVVDLATMREAVRD
                     LGGDPSRINPLAPAEMVIDHSVIVDYFGHPDAFQRNVEREYERNRERYQFLRWGQTAFD
                     EFKVVPPGTGIVHQVNIEHLARVVMVRDGKAYPDTCVGTDSHTTMENGIGVLGWGVGGI
                     EAEAAMLGQPISMLIPRVVGFKLSGKLPAGATATDLVLTITEILRKHGVVGKFVEFYGE
                     GVSSVPLADRATIGNMSPEFGSTCAIFPIDGQTVDYLRLTGRSEEQIALVEAYAKAQGL
                     WLDPQGAEPRFSEYIELDLGTVVPSIAGPKRPQDRIALSDAKRAWRAAVKDYTPSVQGP
                     ADEASDESFPASDSPAIAHDGTGDKPHAAALAGRRPHKRVPVTLADGTSFEIDHGIVSI
                     AAITSCTNTSNPYVMLGAALLARNAVEKGLTRKPWVKTSLAPGSQVVTGYFERSGLQPY
                     LDKIGFNLVGYGCTTCIGNSGPLLPEISDAIQANDLAVTAVLSGNRNFEGRINPDVKMN
                     YLASPPLVVAYALAGTMDIDLDHEPLGTGSDGEPVYLRDIWPSPDEVSAVVHSSIGRDM
                     FERDYADVFKGDEHWRSLPVPTGDTFEWDPSSTYVRKAPYFDGMPEQPEAVHDITGARV
                     LVKVGDSVTTDHISPAGSIKVGTPAAQYLQANGVEVRDFNSYGSRRGNHEVMIRGTFAN
                     IRLRNQIAPGTEGGYTRDFTQPDGPVSFIYDASVNYAAAGTPLVVLAGKEYGSGSSRDW
                     AAKGTALLGVRAVIAESYERIHRSNLIGMGVLPLQFPEGATAESLGLTGEETFDITGVE
                     ELNKGVTPSTVRVKAGDVEFDAVVRIDTPGEADYYRHGGIMQYVLRSLLAK"
     gene            complement(6872..7600)
                     /locus_tag="ASC57_RS26660"
     CDS             complement(6872..7600)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893184.1"
                     /locus_tag="ASC57_RS26660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metal-dependent hydrolase"
                     /protein_id="WP_055505954.1"
                     /transl_table=11
                     /translation="MMGHTHAMTGAIAWLALAPPLATLPLLNESSRFIDTGIMATALTP
                     PELIAGALICAGAAMLPDLDHPSATIAQTFGPVTWVLSKAVSWLSGGHRAATHSLAFAV
                     ALGFGAHWLATTYPIGRDIMVVLLVGLALRAIGIGIPGNKAGSAMVNAGLTAGLYAVFL
                     SLGVGYAWLGLAVGVGCLVHVAGDCMTERGCPVLWPLKAKWVLPWKIGIKTGKTFEQKI
                     LAPVLSIAIVGLLFWRLAPV"
     misc_feature    complement(7643..7657)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.15"
                     /tool="antismash"
     misc_feature    complement(7817..7832)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     misc_feature    complement(7818..7831)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.67"
                     /tool="antismash"
     gene            7910..8650
                     /locus_tag="ASC57_RS26665"
     CDS             7910..8650
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020542885.1"
                     /locus_tag="ASC57_RS26665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_055505955.1"
                     /transl_table=11
                     /translation="MTTAHAAGSPWPGAHEYKQAAREALKAMAEAFEHMGEQVGEHMSR
                     HHHHHRGGPHEHRARGRRGPFPFDFGHGPWGGPGGPFGGHRGGWGGRGRKAKRGDVRAA
                     ILALLAEAPRNGYQIIQEIAERSEGGWKPSPGAVYPALQQLTDEGLVISEENEGRKTFR
                     LTDEGRAYVEAHADEVRAPWDEMRPDIDDSTAELWQIARQSAFAMMQVLQTGTDAQIRE
                     ARKTLVETRRKLYQILADGEPGEE"
     gene            8701..9246
                     /locus_tag="ASC57_RS44765"
     CDS             8701..9246
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017568604.1"
                     /locus_tag="ASC57_RS44765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF1707 domain-containing protein"
                     /protein_id="WP_055505956.1"
                     /transl_table=11
                     /translation="MDRNDLRIGDAEREQTMAALREHFAQGRLTHEELDERLDRTLAAK
                     TARDLAEVTADLPGSPRTGQGPAPYAPPYAPHAPFPEGGAWPAHDREAWREAMRAHRRQ
                     MRALHHRARGEAHRHGSWAGRPPWRHHRGPHPIVPVLFFLALAGLIFGGFGVFKVLLVV
                     WVGAMLFSLVRRSIHHRR"
     misc_feature    8729..8744
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 23.31"
                     /tool="antismash"
     gene            complement(9209..9811)
                     /locus_tag="ASC57_RS26675"
     CDS             complement(9209..9811)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045158.1"
                     /locus_tag="ASC57_RS26675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6879 family protein"
                     /protein_id="WP_055505957.1"
                     /transl_table=11
                     /translation="MTPREFGERFFDFAATAFRVEARDAYAVSAEAEAMRRFLAGEPYG
                     LEWLDGWLRAVAGAAAQGRAVRRVRVVSRPLGDYARFGLDVARHAVRAGEEIRYLPRER
                     AAALGVPERDCWLFDDARLALLDFDGDGVLRAVEPVTDPALVASQRAANELAWREAVPA
                     EAFARAVLPPAPSAPVEAGRARAGRVSGGGGSSGGPG"
     misc_feature    9778..9791
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.57"
                     /tool="antismash"
     aSDomain        10001..10282
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_ASC57_RS26680_Pantocin_Microcin_RRE.1
                     "
                     /evalue="7.50E-16"
                     /identifier="RREFam017.1"
                     /label="ASC57_RS26680"
                     /locus_tag="ASC57_RS26680"
                     /protein_end="94"
                     /protein_start="0"
                     /score="49.0"
                     /tool="antismash"
                     /translation="MRLPRVKPGHEPFRTGPRTVRVGGHVYGVAAEITDPDGLAWAALT
                     AMDGSRTAEDVVAAVLEAVPGATAARARAVVRALVASGHVEDAAAPPPP"
     gene            10001..11065
                     /locus_tag="ASC57_RS26680"
     CDS             10001..11065
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013094.4"
                     /locus_tag="ASC57_RS26680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_063792224.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 2.5e-14,
                     bitscore: 49.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 1.1e-39, bitscore: 132.1,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLPRVKPGHEPFRTGPRTVRVGGHVYGVAAEITDPDGLAWAALT
                     AMDGSRTAEDVVAAVLEAVPGATAARARAVVRALVASGHVEDAAAPPPPELSARELDRY
                     SRTQAYYRHVDRTPREHGWHAQLALRRSSVLVVGLGGTGGHAAWALTAAGVGRLHCVDA
                     DVVELSNLSRQVLYDERDVGRPKAEAALDRLRPVNSGVELTGERRRVTGPGDLAALAAD
                     HDVLALCADEPGGPDGIRAWADRTGKPWVGGGYHGPLVTVGVFAPGGPCHACLAAGEAE
                     RVGSAPSGPRGAGATPASAGLSGLLTAQAVLTLLTGTPPLEPGYVHGLNLLAPGAPVYA
                     RHPPRPGCGTCRAP"
     gene            11062..12297
                     /locus_tag="ASC57_RS46070"
     CDS             11062..12297
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC57_RS46070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_269085618.1"
                     /transl_table=11
                     /translation="MTRVELHDLRWRRDRDGWLVGRMDTGAVVAVPEVGMRAVLLLRDG
                     LSVEETRARLLEECSVRLDVAGFVAGLARAGLLTVAGAAPAGQRRPPPRPTFAWLRPRH
                     VRWASSPALPALALLAVLSAAVLVAARPGLLPHWRDLLWSPHGTLVLLGQAAAGWTLVL
                     AHELAHLVTARAAGVPGRITLGTRLQFLAAQTDVSGIWLAERRERLTVYLAGMATDLTA
                     AALCLLASSVTGRQAVLSLVVLTALTMVAAQFLVFMRTDVYFVLQDLTGCRDLYGEAVA
                     YLRHLVVRRGPDPSLRLPPRERVSVRAYTLVLVAGTAGCLAVAGATTVPALLAVLGGAV
                     RGVAGARGAPGVLDGLAVLAVVGGTQALWARAWWRRHGPRVRRQGRALTAHRLRPADRG
                     RRRRARLRPPRP"
     misc_feature    12408..12422
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.09"
                     /tool="antismash"
     misc_feature    complement(12418..12432)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.73"
                     /tool="antismash"
     misc_feature    12419..12432
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.69"
                     /tool="antismash"
     misc_feature    complement(12420..12433)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.58"
                     /tool="antismash"
     misc_feature    complement(12424..12439)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 16.92"
                     /tool="antismash"
     gene            12495..13253
                     /locus_tag="ASC57_RS45600"
     CDS             12495..13253
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012415.4"
                     /locus_tag="ASC57_RS45600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CAP domain-containing protein"
                     /protein_id="WP_236714953.1"
                     /transl_table=11
                     /translation="MRTSLGVVTGLVGLAALSLPAALPAAADTESQTCQVSVAVPGAVA
                     GGRIEASATRKGCDGPALLRVRLKHAQPGPDKVVKSGATRTGSVAVRLACAPGTYYAFA
                     TDYSGHTKTSRPVKLTCAPGTTEENEVVRLTNEERAKGGCKPLKHDPRLREAAYGHSAD
                     MAARGYFDHTSQDGRDVMDRIRAAGFTGGSAWAENIAMGQPTPAAVVKGWMTSTGHRAN
                     IMNCSYTLIGVGAAKDAKGQIYWTQDFAAN"
     gene            complement(13427..14314)
                     /locus_tag="ASC57_RS26695"
     CDS             complement(13427..14314)
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012318.4"
                     /locus_tag="ASC57_RS26695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="trypsin-like serine protease"
                     /protein_id="WP_063792226.1"
                     /transl_table=11
                     /translation="MFTTALAALVSAGLTLAGTAPVAAASTSAAPAEARAVVQAATGGR
                     PAIIGGRSASETYSFMASFQLKSMPQHHCGGALVAPDWVVTAAHCEGLMKPGKTQVRIG
                     SPDRSRGGELTSVKQVITHPRWTESGQESGDLALVQLDRPVQAQPIAVGAQPVRVGDQT
                     RVLGWGMTCDDRDDPACAGPDLLQELDTVRVADNRCSYLADGSELCTADREGRAASACN
                     GDSGGPQIRKVAGRWELVGATSRDGDDVGESTDGRAGCATGPDGGPGVGIWTDVTHYRS
                     WILTTIAAQAHAAS"
     misc_feature    complement(14409..14424)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            complement(14420..14917)
                     /gene="mug"
                     /locus_tag="ASC57_RS26700"
     CDS             complement(14420..14917)
                     /EC_number="3.2.2.28"
                     /GO_function="GO:0000700 - mismatch base pair DNA
                     N-glycosylase activity [Evidence IEA]"
                     /GO_process="GO:0006285 - base-excision repair, AP site
                     formation [Evidence IEA]"
                     /codon_start=1
                     /gene="mug"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631353.1"
                     /locus_tag="ASC57_RS26700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="WP_055505959.1"
                     /transl_table=11
                     /translation="MLDDVLGPSLDVLFCGINPGMTSAATGHHFARPGNRFWPALHLSG
                     FTPRRLAPSEQHLLPSYGLGITNIVARPSAKASELTRDELVAGGERLAVLAAEARPRIL
                     AVLGVSAYRVAFARPKATVGPQEHDLAGTPVWVLPNPSGLNARWSLDAIASELARLRSH
                     LG"
     gene            complement(14928..16328)
                     /locus_tag="ASC57_RS26705"
     CDS             complement(14928..16328)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017555828.1"
                     /locus_tag="ASC57_RS26705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar porter family MFS transporter"
                     /protein_id="WP_055505960.1"
                     /transl_table=11
                     /translation="MASHAARHEHLGHVVFITAAAAIGGFLFGYDSSVINGAVVGIQRY
                     FQVGAVETGFVVAIALLGSAVGAWVGGGLADRWGRTRSMQFAALLFAVSSIGQMLPFAI
                     WDLAAWRVIAGFAIGMASVLGPAYIAEVAPAAYRGRLGSFQQLAIVLGIAVSQLVNFVV
                     ASFAGGSVNSPLGALQAWQWMLGACAVPALLYLLFALNIPESPRYLVMRGRTERAREVL
                     AEVEGGEVDLDDRIAEIQHVLRTERVPGLGELRGPALGLLPIVWVGIILSVFQQFVGIN
                     VIFYYSTVLWQSVGITQSNSLLISFSSSVINIIGTFVAIALVDRIGRRPLLLIGSAGMA
                     VSLGTAAWAFSASRKVGGVVTLPPPEGPIALVAANLFVLFFALSWGVVVWVLLGEMFPN
                     RIRAAALGVAAAAQWIANWAITVSFPALAEWNLTLTYAGYACFALLSFLFVTRRVKETK
                     GRRLEEMG"
     gene            complement(16411..18894)
                     /locus_tag="ASC57_RS26710"
     CDS             complement(16411..18894)
                     /GO_function="GO:0004113 - 2',3'-cyclic-nucleotide
                     3'-phosphodiesterase activity [Evidence IEA]"
                     /GO_function="GO:0051731 - polynucleotide
                     5'-hydroxyl-kinase activity [Evidence IEA]"
                     /GO_process="GO:0042245 - RNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017571266.1"
                     /locus_tag="ASC57_RS26710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polynucleotide kinase-phosphatase"
                     /protein_id="WP_055505961.1"
                     /transl_table=11
                     /translation="MISVPELSLVVLVGVSGSGKSTFAARHFKPTQVVSSDFCRGLVSD
                     DENDQAATPAAFDLLHHIVGVRLSRGLLTVVDATNVQYQARKSLVELARSHDVLVDAVV
                     LDVPEEVAIARNADRPDRDFGPGVVIRQRKDLRRSLGRIAKEGFRRVHVLRGVEEIEAA
                     GVAYEKAWTDRRELTGPFDVIGDVHGCRSELEALLRKLGWRGLSHPEGRTAVFVGDLVD
                     RGPDTPGVLRLVMDMVEAGTALCVAGNHEVKLSRALDGRKVRVAHGLQESLDQLAAEPP
                     EFVARARAFMDGLISHYQLDGGRLVVAHAGLKEPYHGRASGRVRSFALYGDTTGETDEY
                     GLPVRLPWAEEYRGRATVVYGHTPTDTPVWVNNTICLDTGCVFGGHLTALRYPEREIVQ
                     VRAEKTWYEPVKPLGGPARDAAARGSTVLDIGDVAGTRHVETRYGGRFKIAEENAAAAL
                     EVMSRFAVDPRWLVYLPPTMAPPRTSTLDGYLEHPHEAFEEFAAAGVREVVCEEKHMGS
                     RAVAVLARTPEAAAARFGVTDGAAGAVYTRTGRPFFADTAPLVERLRAACEPLWEALGS
                     DWVVLDCELLPWSAKAEGLIRSQYASVGAAARAALPEAVAALEAAAGRGLDVAALLDRT
                     RRREANARLFRDAYARYCWPVGGLDGLDGVRVAPFQILACEGRATALEPHAWHLSTLAL
                     LDSPLITRTRHLFVDLESPDSRDGAVAWWEALTASGGEGMVVKPAAYTPGRVQPGVKVR
                     GREYLRIIYGPDYTESLDVLRRRFLGKKRSLALREYALGLEALARLAGGEPGWRVHEPV
                     FAVLALESEPVDPRL"
     gene            complement(18878..20368)
                     /locus_tag="ASC57_RS26715"
     CDS             complement(18878..20368)
                     /GO_function="GO:0008173 - RNA methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042245 - RNA repair [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631304.1"
                     /locus_tag="ASC57_RS26715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="3' terminal RNA ribose 2'-O-methyltransferase
                     Hen1"
                     /protein_id="WP_055505962.1"
                     /transl_table=11
                     /translation="MLLTITTTSRPATDLGFLLHKHPERVQEFGGSYGTATVFYPEAGE
                     DRCTAALLLEVDPVALVRSRGRNSPDFSLSQYVNDRPYAASSLLAVALADVFRTARAGR
                     CAARPELPGTALPLEIRLPALPCRGGPELAERLFAPLGWQVSAESVPLDEGFPAWGESR
                     YVRLALAGTLRLSDALNHLYVLLPVLDDGKHYWIAPDEVDKLVRAGEGWLGGHPERGLI
                     TRRYLGRRWSLARTALARLAELGDETEEELEPPVAEEASPEETAADEAAAAETAAEGAA
                     GAPAEGEPGQERKPRSLSVLRREAVLGVLEELGAVSVADLGCGQGELVAALLARPRFAR
                     VAGMDVSSMALTIAARRLRLDRMPDAVRARLTLFQGSLTYTDKRLRGYDAAVLMEVVEH
                     VDPPRLAALEHVVFGHARPAHVVVTTPNVEYNVRYPFLTGLRHPDHRFEWTRAEFAAWA
                     ARVAAEHGYEVAFRPVGDDDPEVGPPTQMGVFTRDQRS"
ORIGIN
        1 aagaacatcg ccagcgtggc ccggatctgc ggccccttcg cgctctggta caccagcgcg
       61 atcggcggcc ccccgatgcc cgtggccgtg ccggtgacgc ccgacaggaa gcccgcgccg
      121 gtgatggtgg cgccgttgcg cggcaccctc ggcgccctcg ccgtgagcac caccgcgagc
      181 agcaccatga cgcccacgaa cacgcccagc gtcgtcaccg agacgtacac gacgatgagc
      241 gcgccgacgg cgctgcccgg caggcgcccc agcaccgcga acccgacccc gcgccagtcc
      301 acgcgccgcc actccgcggc cagcgtgagc agcggcagcg tcatgttgac cacctggatc
      361 gcccccggca tgacgccgtg gtccagcatc gtcagcacgg gcgccgcgac cagccccagc
      421 ccgaacccca cgctcccctg caccaccgcg ccgcagaaca ccgccacgcc gcccaccacc
      481 agcactaacg ccacatcggt catgggcaga gtcaaccacc cgccgcccca cgggcctcat
      541 ggggcccagg aaacatcgtc tccatgactg acgaggtttc ctccgtgtgc taacgtcgtc
      601 tctaagagag acgaagtcgg gcttcgtctc gcgcgtggta gtaatgagat ccgcagagga
      661 ggccgtcccg acagagttgg tgcaccatga ccgagcgtta cctcggcgta ctcggcatcg
      721 gcgaggcgct gggcgtgagc cggcacgcgg tgcacaagtg gcgatcccgc caccccggcg
      781 gctccggcca cccgttcccc gagcccgacg tcgagatcga cggcaccccc ggctggcggc
      841 ccgaccggct cgccgagatc atccgctggc gcgacggcct gcccggccgc ggcgccggcg
      901 gcggccgtcc caccgccgcc cgccaggagt acctgaagga ggcggcggcg cgcggaatgg
      961 accgcgaaga ggcgctgcgc gcgctcgcca cgctcggcga ggagttcccc gagatgaccg
     1021 agccggagat ctgcgcctgg ctcctcggcc actggcgcgg ctagcggcac cctccccgcg
     1081 cctccccgca ccacccccga cggaaggcga tgacgcatgc ccgcgacccg cggcgagacc
     1141 gcacccggat tcgaagcagt acgcgagacg ttcgaggccc acctggccgg cgagccggag
     1201 gcgggcgccg ccgtggccgc ctacctgcac ggcaggaagg tcgtggacct gtggggcggc
     1261 gtcgccgacc ccgcgaccgg ccgcccctgg gagcgcgaca ccctccaggt cgtcttctcc
     1321 accaccaagg gcgtcaccgc cgcgtgcgcc cacctgctgg ccgagcgggg cgaactggac
     1381 ctcgacgcgc ccgtcgccgc gtactggccg gagttcgcgg cgaacggcaa ggaccgggtc
     1441 ccggtgcggt ggctgctcac ccaccaggcc gggctgcccg cgatcgaccg tccgatcagc
     1501 cccgcgcagg ccctcgcctg ggagccgatg gtgaccgcgc tggccgtcca gcggcccctg
     1561 tgggagccgg gcaccgacca cggctaccac gcgcacacct acggctggct cgtcggagag
     1621 gtcgtccgcc gggtcagcgg gcggagcctg gggaggtacc tcgcccaaga gatcgccgcg
     1681 ccgctcggcc tcgacctgtg gatcgggctg cccgcggccg aactgccccg ggtcagccgg
     1741 ctcgtcaccg acccgggcga ccccggcgcc ctggccggga tcgacccgga cgcccttccc
     1801 gaacccgcgc gcgagctgct gcgcgcctac accgacccca cgtcgctcac catgcgggcc
     1861 atgaccgtcg tcacgccgct gctcgaccac gacgacccgc gcgaacaggt cgccgagctg
     1921 cccgcgacca acggcgtctg caccgcccgc gcgctcgccc gcttctacgc cgcgctcatc
     1981 ggcgaggtgg acgggcggcg cgtcctcgcg cccggcacgc tcgctgcggc gaccgccgag
     2041 caggtcagcg gggtggaccg cgtcctgcgg acgcccgtgc gcatcggcac gggcttcggg
     2101 ctgccgacgc ctgacgcctt ctggtacagc ccgaccgcct tcgggttccc cggctacggc
     2161 ggctcgatcg gtttcgccga cccggcgagc ggcctcgcct tcgcctacgt gacgaaccac
     2221 ctcaagccaa acaccccgga ccccagggcc gccgccctcc tggacgcggt gcgcagcgca
     2281 ctcgccccga gcccccgctg aggggacgtc atggagcgac ggaagcgggc cccgccgccc
     2341 ccggcggcac cacgccggac cgcaggccgg cgctcacccc gcgtcccttc cgccgtggcg
     2401 agaacacccg gccgggcggc gcgatgcggg cgtggtgggg gcgagaacac ccagcccagc
     2461 cgcgggatac ggacgcggtg gggcgagagc acccagcccg gccgcgggat acggacgcgg
     2521 tggaggcgag agcgcccagc ccggcggcgg gatgcggccc gcccgcccgc gaggctctag
     2581 gcttccgggc gtgcccatcc ccctgccgcc gatccccttg ccgcccgcct ccctcccgcc
     2641 tgactccctg ccgcccgcct ccctcccgcc tgactccctg ccgcccgcct ccctcccgcc
     2701 tgactccctc ccgcccgcct ccctcccgcc tgtctccccg ccggcgccct tcgccacccg
     2761 cgttcccgct tctcctcccg ggcggctctc cccgtccgca cgcgcgcgtc ctgtcagggg
     2821 tgggcgcggc gggggcccag cgggcgcgct gcccggcggc gccgtcgcct gcctggtcgc
     2881 ggcgtgcctc gtcgcggccg ttccctcggg agcggccgcc gccacgccgg ttgcgacaac
     2941 ggcgacagcc acggggaccg cggcggtcgc gagcaccgcg gcgggcacga gcaccgcggc
     3001 gggcacgacg acgacggcgg tcggtccgcc gtccagatcg gcggtcggtc cggcgtccgg
     3061 gtcggcgtcg gggccggggg gcgagttctc cgggacgggc aggctctcgc gtggctcgtg
     3121 ccacgagccg ccgctcgtca ccggcggcat cccgcgcgcc aaggagtacc tggaagccgt
     3181 cgtggcctgc atgaacaggt cgtggggcgg ccacttctcg cgtgcccgcg aggcgttcgc
     3241 caggcccgcc gtccgtttct acgacgagcc cgtcggcacg gtgtgcggcg tcccgtggcc
     3301 ctccgacgcc gccgcgttct actgcaccaa ccgcaggacc ctggtcttcc cgctctcggg
     3361 cgcgtggatc gagaaccgca ccgacctgta ccccttcaag gtcgccgccc acgagtacgg
     3421 ccaccacctg cagagcctca ccggcgtcag gcgtcgctac gaggcccgcc tgcgctctca
     3481 gccgagccgt caggacgagc tgggccgccg ctacgagctc caggccgact gcctgtccgg
     3541 cgtgttcctc ggcagcgtac gcggctccct ggggcgcggc gagcgcgact gggacgccct
     3601 cctcgacgcc gtgcgcgcca gcggcgacga gggcggctac cgcagccacg gcaagggcgc
     3661 cacccgggtc gcctggctga agcgcggcct cggctcgcgc tcccccgccg cctgcgacac
     3721 ctggtcggcc cccgcgtcac aggtcggctg accgcgccgg ggcgtgcggc ggccgcccgc
     3781 ctcgggccgg ggcgggcatg gcaaagcgcc gccccggcgg agggtggtcc gctggggcgg
     3841 cgcttcgtgg ctcgggtggt tcccccgaat cgggcgcgtg aggatcacgc ccctgtcccg
     3901 gccggtgccg ggctccctgg cctccgcccg gctcatgacc gggcggaggg cggaagtcac
     3961 ttggcgagca gagaccgcag aacgtactgc atgatgccgc cgtgccggta gtagtcggcc
     4021 tcgcccggcg tgtcgatgcg gacgaccgcg tcgaactcca cgtcgcccgc cttgacgcgc
     4081 acggtgctcg gcgtgacgcc cttgttgagc tcctcgactc cggtgatgtc gaaggtctcc
     4141 tcaccggtca ggcccagcga ctcggccgtg gcgccctcgg ggaactgcag cgggagcacg
     4201 cccatgccga tgaggttgga gcggtggatg cgctcgtacg actcggcgat gacggcgcgg
     4261 acgccgagca gcgccgtgcc cttggccgcc cagtcgcgtg aggagccgga gccgtactcc
     4321 ttgccggcga ggacgaccag cggcgtgccg gcggcggcgt agttgacgga ggcgtcgtag
     4381 atgaacgaca ccgggccgtc gggctgggtg aagtcgcggg tgtagccgcc ctcggtgccc
     4441 ggcgcgatct ggttgcgcag gcggatgttg gcgaacgtgc cgcggatcat cacctcgtgg
     4501 ttgccccggc gggagccgta cgagttgaag tccctgacct cgacgccgtt ggcctggagg
     4561 tactgcgcgg ccggggtgcc gaccttgatg gagccggcgg gcgagatgtg gtcggtggtg
     4621 acggagtcgc cgaccttgac cagcacccgg gcgccggtga tgtcgtggac cgcctccggc
     4681 tgctcgggca tgccgtcgaa gtagggcgcc ttgcgcacgt acgtcgagga cgggtcccac
     4741 tcgaaggtgt cgcccgtggg caccggcagg gagcgccagt gctcgtcgcc cttgaacacg
     4801 tcggcgtagt cgcgctcgaa catgtcacgg ccgatcgagg agtggacgac ggcggagacc
     4861 tcgtccggcg acggccagat gtcgcgcagg tagacgggct cgccgtcgga gcccgtgccg
     4921 agcggctcgt ggtcgaggtc gatgtccatg gtgccggcca gcgcgtacgc gacgaccagc
     4981 ggcggcgacg ccaggtagtt catcttgacg tcggggttga tgcggccctc gaagttgcgg
     5041 ttgccggaca ggacggcggt gaccgcgagg tcgttggcct ggatggcgtc ggagatctcg
     5101 ggcagcagcg ggccggagtt gccgatgcag gtggtgcagc cgtagccgac caggttgaag
     5161 ccgatcttgt cgaggtacgg ctggaggccg gagcgctcga agtagccggt gacgacctgc
     5221 gagccgggcg ccagggacgt cttgacccac ggcttgcggg tcaggccctt ctcgacggcg
     5281 ttgcgggcga gcagcgcggc gccgagcatg acgtacgggt tggaggtgtt ggtgcacgag
     5341 gtgatcgcgg cgatcgagac gatgccgtgg tcgatctcga acgacgtgcc gtcggccagc
     5401 gtgaccggca cccgcttgtg cggccggcgg ccggcgagcg cggcggcgtg cggcttgtcg
     5461 ccggtgccgt cgtgggcgat ggccggggag tcggaggcgg ggaacgactc gtcggacgcc
     5521 tcgtcggccg ggccctggac gctcggcgtg tagtccttga cggcggcgcg ccaggcccgc
     5581 ttggcgtcgg acagcgcgat gcggtcctgc gggcgcttgg ggccggcgat cgacgggacg
     5641 acggtgccga ggtcgagctc gatgtactcg gagaaccgcg gctcggcgcc ctgcgggtcg
     5701 agccagaggc cctgggcctt ggcgtacgcc tcgacgaggg cgatctgctc ctcggagcgg
     5761 ccggtcaggc gcaggtagtc gacggtctgg ccgtcgatcg ggaagatcgc gcaggtggag
     5821 ccgaactcgg ggctcatgtt gccgatggtg gcccggtcgg cgagcggcac ggaggagacg
     5881 ccctcgccgt agaactcgac gaacttgccg accacgccgt gcttgcgcag gatctcggtg
     5941 atggtgagca ccaggtcggt ggcggtggcg cccgcgggca gcttgccgct gagcttgaag
     6001 ccgaccacgc gcgggatcag catggagatc ggctggccga gcatggcggc ctcggcctcg
     6061 atgccgccga cgccccagcc gagcacgccg atgccgttct ccatggtggt gtgggagtcg
     6121 gtgccgacgc aggtgtcggg gtaggccttg ccgtcgcgca ccatgacgac gcgggccagg
     6181 tgctcgatgt tgacctggtg gacgatgccg gtgccgggcg gcacgacctt gaactcgtcg
     6241 aaggcggtct ggccccagcg caggaactgg tagcgctcgc ggttgcgctc gtactcgcgt
     6301 tcgacgttgc gctggaaggc gtcggggtgg ccgaagtagt cgacgatgac ggagtggtcg
     6361 atgaccatct cggccggcgc gagcgggttg atgcgcgacg ggtcgccgcc caggtcgcgc
     6421 acggcctcgc gcatggtggc caggtcgacc acgcagggca cgccggtgaa gtcctgcatg
     6481 atcacgcggg cgggggtgaa ctggatctcc acgctgggcg tggcgttcgg gtcccagccg
     6541 gcgagcgccc tgatgtggtc ggcggtgatg ttcgcgccgt cctcggtgcg aagcaggttc
     6601 tccagcagga tcttgaggct gtacgggagg cgtgcggcgc cctcgacggc atccagccgg
     6661 aaaatctcgt atgacgcgtc gccgacgcgt agcgtgtcac ggctgccgaa gctgttcgcg
     6721 gacacggtga ttcgcctcct ccatagacct gtgctcagtc aaatcctgcc gcaccccggg
     6781 agcgacgcga acgtcgggtg gccccgaccc ccggcacggt tgcagcggat ctctcgacgt
     6841 caagatatat gcagggtatc tcgacatcaa gttaaacggg ggcgagccgc cagaacagca
     6901 ggccgacgat ggcgatcgac agcaccgggg ccaggatctt ctgctcgaac gtcttgccgg
     6961 tcttgatgcc gatcttccag ggcagcaccc atttcgcctt cagcggccac agcaccgggc
     7021 acccccgctc ggtcatgcag tcgcccgcga catgcaccag gcagcccacc cccacggcca
     7081 gccccagcca ggcgtacccg acgccgaggg agaggaagac ggcgtacagg ccggcggtca
     7141 ggccggcgtt gaccatcgcc gagcccgcct tgttcccggg gatgccgatg ccgatggcgc
     7201 gcagcgccag gccgacgagc agcacgacca tgatgtcgcg cccgatcggg taggtggtgg
     7261 cgagccagtg cgcgccgaac ccgagcgcca ccgcgaacgc cagcgagtgc gtggcggccc
     7321 ggtgcccgcc gctgagccag gagaccgcct tgctcagcac ccaggtgacg ggcccgaacg
     7381 tctgcgcgat cgtcgcgctg gggtggtcga ggtcgggcag catggccgcc cccgcgcaga
     7441 tgagggcccc ggcgatgagc tcgggcggcg tgagcgcggt ggccatgatc ccggtgtcga
     7501 tgaaccgcga gctctcgttc agcagtggca gcgtggccag cggcggcgcg agcgccagcc
     7561 aggcgatggc cccggtcatc gcgtgcgtgt gccccatcat gatccggact gtacggcaaa
     7621 gcggaggcaa agcggcgtac gcgcccacac ctcgtgttgg acgggaaccg gcaaagccgc
     7681 tccgacctgc ccggaaacgc agacgaggcc gtctccgcgg cgacagcacc ccccagccct
     7741 gccgacacgg aacgacctcg tctgctctgt ccaacgcctc ctccgtcgat cctgttccca
     7801 gattccgcaa ctttttcgtg atctggctca ctcttcgacg tcccttgcga acgacatgtt
     7861 ctcgatatat ctttgacgca tctagaacag atcgccacaa ggaggaaaaa tgacgacagc
     7921 acatgcggca ggctcgccct ggcccggcgc gcacgagtac aagcaggccg cccgcgaggc
     7981 gctcaaggcc atggccgagg cgttcgagca catgggcgag caggtgggcg agcacatgag
     8041 ccgccaccat caccaccacc ggggcggtcc gcacgagcac cgcgcgcgcg gcaggcgcgg
     8101 ccccttcccg ttcgacttcg gccacgggcc gtggggcggg ccgggcgggc ccttcggcgg
     8161 ccaccgcggc ggctggggcg gcaggggccg caaggccaag cgcggcgacg tccgcgcggc
     8221 gatcctcgcc ctgctcgccg aggccccgcg caacggctac cagatcatcc aggagatcgc
     8281 cgagcgcagc gagggcggct ggaagcccag ccccggagcc gtctacccgg cgctccagca
     8341 gctcaccgac gagggcctcg tcatctccga ggagaacgag ggccgcaaga ccttccgcct
     8401 caccgacgag ggccgcgcct acgtcgaggc gcacgccgac gaggtccgcg ccccgtggga
     8461 cgagatgcgt cccgacatcg acgacagcac cgccgagctg tggcagatcg ccaggcagtc
     8521 ggcgttcgcg atgatgcagg tgctccagac gggcaccgac gcgcagatcc gcgaggcgcg
     8581 caagactctg gtggagaccc ggcgcaagct ctaccagatc ctggccgacg gcgaaccggg
     8641 cgaggagtga cgtcgcgacc ggcgccggac gcccggtccc gtgagagcga ggaagcaggg
     8701 atggaccgca acgacctgcg catcggcgac gccgagcgcg agcagacgat ggccgcgctg
     8761 cgtgagcact tcgcgcaggg ccgcctgacc cacgaggagc tcgacgagcg gctcgaccgc
     8821 accctggccg ccaagaccgc ccgcgacctc gccgaggtca cggccgacct gcccggctct
     8881 ccgcgtacgg ggcaggggcc cgccccgtac gcgccgccct acgcgcccca cgcgcccttc
     8941 cccgaggggg gcgcgtggcc ggcgcacgac agggaggcct ggcgggaggc gatgcgcgcg
     9001 caccgccggc agatgcgcgc gctgcaccac cgggcgcggg gggaggcgca ccgccacggg
     9061 tcgtgggccg gccgtccccc gtggcgccac caccgcggcc ctcacccgat cgtccccgtc
     9121 ctgttcttcc tggcgctggc cgggctgatc ttcggcgggt tcggcgtctt caaggtgctg
     9181 ctcgtggtct gggtgggcgc gatgctcttc agcctggtcc gccgctcgat ccaccaccgc
     9241 cgctgacccg cccggcccgc gcccgccccg cctcgacggg ggcggacggg gcaggcggga
     9301 ggacggcgcg ggcgaacgcc tcagcgggga cggcctcgcg ccaggccagc tcgttcgcgg
     9361 cgcgctggct cgccaccagc gccgggtccg tgaccggctc cacggcgcgc agcacgccgt
     9421 cgccgtcgaa gtccagcagg gcgagccggg cgtcgtcgaa cagccagcag tcgcgctcgg
     9481 gcacgccgag cgcggccgcc cgctccctgg gcaggtagcg gatctcctcg ccggcccgca
     9541 cggcgtgccg tgccacgtcc agcccgaacc gcgcgtagtc gcccagcggc cgcgacacca
     9601 cccgcacgcg ccgcacggcc ctgccctgcg cggcggcgcc cgccaccgcg cgcagccagc
     9661 cgtccagcca ctccagcccg tacggctccc cggcgaggaa gcgccgcatg gcctccgcct
     9721 ccgccgacac cgcgtacgcg tcgcgcgcct cgacccggaa ggccgtcgcg gcgaagtcga
     9781 agaaccgttc cccgaactcc cgaggcgtca tcgcaccctc cggcggccgt caccccttga
     9841 cctccccgat atcaccacat ttcatgatct ggacggtcat ttcaagcgaa gggagtaagg
     9901 gtggacgagc aggagacccc cgagctggag atcgagatcc gtctcctcga ccggatcgag
     9961 accacgacgc tctgcatgtc cgaggcctga cggcaaggcc gtgcgcctgc ccagggtcaa
    10021 acccgggcac gagccgttca ggaccggccc gcggaccgtg cgcgtcggcg gccacgtgta
    10081 cggggtcgcc gccgagatca ccgaccccga cggcctggcc tgggcggcgc tgaccgccat
    10141 ggacggctcc aggacggccg aggacgtcgt cgcggccgtc ctggaggcgg tgcccggcgc
    10201 cacggccgcc cgcgcccgag ccgtcgtccg cgcgctcgtc gcctccgggc acgtggagga
    10261 cgccgccgcc cctcccccgc ccgagctgtc ggcgcgcgag ctcgaccgct actcccgcac
    10321 gcaggcctac tacaggcacg tggacaggac gccgcgggag cacggatggc acgcgcagct
    10381 cgcgctcagg cgctcctccg tcctggtcgt cgggctcggc ggcaccggcg gccacgccgc
    10441 ctgggcgctg accgccgccg gggtgggccg cctgcactgc gtggacgccg acgtggtcga
    10501 gctgtccaac ctcagccggc aggtcctcta cgacgagcgg gacgtcggcc gccccaaggc
    10561 ggaggccgcg ctcgaccggc tccgcccggt caactccggc gtcgagctga ccggcgagcg
    10621 tcgccgcgtc accggccccg gcgacctggc cgccctggcg gcggaccacg acgtgctggc
    10681 gctgtgcgcc gacgagccgg gcggccccga cggcatcagg gcctgggccg acaggaccgg
    10741 gaagccgtgg gtgggcggcg ggtaccacgg gccgctggtc accgtcggcg tcttcgcccc
    10801 cggcggtccc tgtcacgcgt gcctggcggc gggcgaggcg gagcgggtcg ggtccgcccc
    10861 ctcgggcccg cgcggcgccg gcgccacccc cgcgtccgcg gggctgtccg ggctgctcac
    10921 cgcccaggcc gtgctcacgc tgctgaccgg gacgccgccc ctcgaacccg gctacgtcca
    10981 cgggctgaac ctgctggccc ccggcgcccc cgtctacgcg cgccacccgc ccaggcccgg
    11041 ctgcgggacg tgccgggcgc catgacccgc gtcgagctgc acgacctgcg ctggcgccgc
    11101 gaccgtgacg gctggctcgt cggccggatg gacacgggcg ccgtggtggc cgtccccgag
    11161 gtggggatgc gggccgtcct gctcctccgg gacggcctgt cggtggagga gacgcgggcg
    11221 cggctgctgg aggagtgctc cgtgcgcctg gacgtggccg gcttcgtcgc ggggctggcc
    11281 cgcgccggcc tgctcaccgt cgccggcgcc gccccggccg ggcagcggcg gcccccgccg
    11341 cgccccacct tcgcgtggct gcggccccgg cacgtgcgat gggcgtcgag cccggcactg
    11401 cccgcgctgg cgctcctggc cgtcctctcc gccgcggtgc tcgtcgcggc ccgccccggc
    11461 ctgctgcccc actggcgcga cctgctgtgg agcccgcacg gcacgctcgt gctgctcggc
    11521 caggcggcgg cgggctggac gctcgtcctg gcgcacgagc tggcgcacct ggtgaccgcg
    11581 cgggcggcgg gcgtgccggg gaggatcacg ctcgggacgc ggctgcagtt cctggccgcg
    11641 cagaccgacg tgtccggcat ctggctcgcg gagcgccggg agcggctgac cgtgtacctc
    11701 gcgggcatgg cgacggacct gaccgccgcc gcgctgtgcc tgctcgcctc gtccgtcacc
    11761 ggccgccagg cggtgctctc gctcgtcgtc ctgacggccc tgaccatggt ggcggcccag
    11821 ttcctcgtgt tcatgcggac ggacgtctac ttcgtgctgc aggacctgac cggctgccgc
    11881 gacctgtacg gcgaggccgt cgcctacctg cgtcacctgg tcgtccggcg cgggcccgac
    11941 ccgtcgctcc ggctgccccc gagggagcgg gtgagcgtgc gggcgtacac gctggtgctg
    12001 gtggcgggca cggcgggctg cctggcggtg gcgggcgcca ccaccgtgcc cgccctgctg
    12061 gccgtgctgg gcggcgcggt gcgcggcgtg gcgggcgcgc gcggagcgcc cggcgtgctc
    12121 gacggactcg cggtgctcgc cgtggtcggc gggacgcagg cgctgtgggc ccgcgcctgg
    12181 tggcgccgcc acggcccccg ggtgcggcgg caggggcgcg cgctcaccgc gcaccggctg
    12241 cgccccgccg accgggggcg ccgccgacgc gcgcgcctgc ggccccctcg cccctagccg
    12301 gtcaggcggg aagggcggcg ccctccccac ctcggcccgg ccgtgacggt ggcccagaag
    12361 gcgcttggac gcttcaccag ccccatcggt tgacaggaat atcagggatt tatgcgaaat
    12421 ttggtgacaa aagggacaga agccgacaga atgcgttggc gatccagcgt ccagccaact
    12481 ggaggaatcc ccctgtgcgt acatccctag gggtggtcac cggcctcgtg ggcctcgccg
    12541 ctctctccct gcccgccgcg ctgcccgccg ccgccgacac ggagtcgcag acctgccagg
    12601 tgtccgtggc cgttcccggc gccgtcgcgg gaggccggat cgaggcgtcc gccacgcgga
    12661 aggggtgcga cgggcccgcg ctgctccgcg tacgcctcaa gcacgcccag ccagggcccg
    12721 acaaggtcgt caagagcggc gccacccgca ccggcagcgt ggcggtccgc ctggcgtgcg
    12781 cccccggcac gtactacgcc ttcgccaccg actacagcgg ccacaccaag acgtcgcgcc
    12841 cggtcaagct gacctgcgcc cccggcacga ccgaggagaa cgaggtcgtc aggctcacca
    12901 acgaggagcg cgccaagggc ggctgcaaac ccctcaagca cgacccgcgg ctgcgcgagg
    12961 cggcgtacgg ccactcggcc gacatggcgg cgcgcggcta cttcgaccac acctcgcagg
    13021 acggccgcga cgtcatggac cgcatcaggg cggccgggtt caccggcggc tccgcctggg
    13081 ccgagaacat cgcgatgggc cagcccaccc cggccgccgt ggtcaagggc tggatgacca
    13141 gtacgggcca ccgggccaac atcatgaact gctcgtacac gctgatcggg gtcggcgcgg
    13201 ccaaggacgc caagggccag atctactgga cccaggactt cgccgccaac tgaccaccgc
    13261 ccacctgccg cacggccacc ggccgcgcga gcacgggccg cgcgtgcggc gccctcagga
    13321 ggggcgccgc acgccatgcc gtgcaggcgg cgcacatgag acccgcgccg cagcaggcgg
    13381 gcgcggcttc aggaagcggc atgcgccgcg gcgagcggac gcagtctcag gaggcggcgt
    13441 gcgcctgcgc ggcgatcgtc gtgaggatcc aggaccggta gtgggtgacg tcggtccaga
    13501 tgccgacgcc cggcccgccg tcgggcccgg tggcgcaccc ggcgcgtccg tcggtggact
    13561 cgccgacgtc gtcgccgtcg cgggaggtgg cgccgacgag ctcccaccgg cccgcgacct
    13621 tgcggatctg cgggccgccc gagtcgccgt tgcaggcgct ggccgcgcgt ccttcgcggt
    13681 cggcggtgca cagctcgctg ccgtcggcga ggtaggagca ccggttgtcg gcgacgcgca
    13741 cggtgtcgag ctcctgcagc aggtcggggc ccgcgcaggc ggggtcgtca cggtcgtcgc
    13801 aggtcatgcc ccacccgagg acgcgggtct ggtcgcccac ccgcaccggc tgcgcgccga
    13861 cggcgatggg ctgggcctgc accggccggt cgagctgcac gagcgcgagg tcgcccgact
    13921 cctggccgga ctcggtccag cggggatggg tgatgacctg cttgacgctg gtgagctccc
    13981 cgccccggct gcggtcgggg gagccgatgc gcacctgcgt cttgccgggc ttcatcagcc
    14041 cttcgcagtg ggcggccgtg accacccagt cgggggcgac gagcgcgccg ccgcagtggt
    14101 gctggggcat cgacttgagc tggaacgacg ccatgaacga gtaggtctcg gaggccgagc
    14161 gcccgccgat gatggcgggg cgtcccccgg tggcggcctg cacgacggca cgcgcctcgg
    14221 cgggggcggc ggaggtggag gcggcggcca cgggggcggt gcctgccagg gtcagaccgg
    14281 cggacacgag ggcggcgagg gcggtggtga acacccgtct ccttccagta aaaggggagc
    14341 tcctggaacg gtccagaggc ggctgcgtac ccgacaggct acccgctcgt ttccgtgtca
    14401 tgacccgtcg tgaccggtgt caccccaggt gggagcggag gcgggcgagt tcggaggcga
    14461 tggcgtcgag gctccagcgg gcgttcaggc cgctgggatt cggcaggacc cagacggggg
    14521 ttccggccag gtcgtgctcc tgggggccca ccgtggcctt cggccgggcg aaggccacgc
    14581 ggtaggccga gaccccgagc acggcgagga tcctcggccg cgcctcggcg gccaagacgg
    14641 ccagccgctc accgcccgcg accagttcgt ccctggtcag ctcggacgcc ttggcgctcg
    14701 ggcgggccac gatgttggtg atgcccagcc cgtacgaggg gagcaggtgc tgctcggacg
    14761 gcgcgagccg gcgcggcgtg aagccggaca ggtggagcgc gggccagaag cggttgcccg
    14821 gcctggcgaa gtggtggccg gtggccgcgg acgtcatccc ggggttgatg ccgcagaaca
    14881 ggacgtcgag cgagggtccg agcacgtcgt cgagcacgtg ccggagacta gcccatctct
    14941 tccagtctgc ggcccttggt ctccttcacc ctgcgcgtga cgaagaggaa cgacagcagg
    15001 gcgaagcagg cgtacccggc gtaggtgagc gtcaggttcc actcggcgag cgcggggaac
    15061 gacacggtga tcgcccagtt ggcgatccac tgggcggcgg cggcgacgcc cagcgcggcg
    15121 gcgcggatcc ggttggggaa catctcgccc agcaggaccc agacgaccac gccccacgac
    15181 agggcgaaga acagcacgaa caggttggcc gcgaccagcg cgatcggccc ctccggcggc
    15241 ggcagggtga ccacgccgcc caccttcctt gacgcgctga acgcccacgc cgccgtgccg
    15301 agcgacacgg ccatgccggc ggagccgatg agcagcaggg gcctgcgccc gatccggtcc
    15361 accagggcga tggcgacgaa cgtgccgatg atgttgatca ccgagctgga gaagctgatg
    15421 agcagcgagt tgctctgcgt gatgccgacc gactgccaca gcacggtcga gtagtagaag
    15481 atcacgttga tgccgacgaa ctgctggaac accgacagga tgatcccgac ccagacgatc
    15541 ggcagcagcc ccagcgcggg cccgcgcagc tctcccagcc ccggcacccg ctccgtcctg
    15601 agcacgtgct ggatctccgc gatgcggtcg tcgaggtcga cctcgccgcc ctcgacctcg
    15661 gccagcacct cgcgggcccg ctcggtgcgg ccgcgcatga cgaggtagcg gggcgactcg
    15721 gggatgttca gcgcgaacag caggtagagc agcgccggca cggcgcacgc gcccagcatc
    15781 cactgccacg cctgcagcgc gcccagcggg ctgttcacgc tgccgcccgc gaagctcgcc
    15841 accacgaagt tgacgagctg cgacaccgcg atgccgagca cgatggcgag ctgctggaac
    15901 gacccgagcc tgccccggta ggccgccggg gccacctccg cgatgtacgc ggggcccagc
    15961 accgacgcca tgccgatggc gaagcccgcg atcacgcgcc aggccgccag gtcccagatc
    16021 gcgaacggca gcatctgccc gatcgagctc accgcgaaca gcagcgccgc gaactgcatc
    16081 gaccgcgtac gcccccaccg gtcggcaagc ccgcctccca cccacgcgcc cacggccgag
    16141 ccgagcagcg cgatggccac cacgaacccg gtctccaccg cccccacctg gaagtagcgc
    16201 tggatgccca cgacggcgcc gttgatgacg gagctgtcgt acccgaacag gaacccgccg
    16261 atggcggccg cggcggtgat gaagacgacg tgacccaggt gctcgtggcg tgctgcgtga
    16321 ctagccatgt cggtcccttc cccgggagga gggacctatc cgtggcccgg cgcggcgcct
    16381 accgcgtccc cgggccgggc ggggaaccgg tcacagccgc ggatctaccg gctcggactc
    16441 cagggcgagc acggcgaaca ccggctcgtg cacccgccag cccggctcgc cgccggccag
    16501 ccgcgccagc gcctccagcc cgagcgcgta ctcgcgcagc gcgagcgagc gcttcttgcc
    16561 caggaagcgc ctgcgcagca cgtccagaga ctcggtgtag tcggggccgt agatgatgcg
    16621 caggtactcc ctgccgcgta ccttcacccc cggctgcacc cggcccggcg tgtacgccgc
    16681 cggcttgacg accatgccct cgcctccgga ggcggtcagc gcctcccacc aggcgaccgc
    16741 cccgtcgcgg gagtccggcg actcgaggtc gacgaacagg tgccgggtcc gggtgatcag
    16801 gggcgagtcg agcagcgcca gcgtggacag gtgccaggcg tgcggctcca gcgccgtggc
    16861 ccggccctcg caggccagga tctggaacgg cgcgacccgg acgccgtcga ggccgtcgag
    16921 gccgccgacg ggccagcagt agcgggcgta ggcgtcgcgg aacagccgcg cgttcgcctc
    16981 gcgccggcgc gtcctgtcca ggagggcggc cacgtccagg ccgcgtcccg ccgccgcctc
    17041 cagggccgcg acggcttcgg gcagcgccgc gcgggccgcc gcgccgacgg aggcgtactg
    17101 gctcctgatc agcccctccg ccttggccga ccagggcagc agctcgcagt cgagcaccac
    17161 ccagtcggag ccgagcgcct cccacagcgg ttcgcacgcg gcgcgcagcc gctccaccag
    17221 cggcgccgtg tcggcgaaga acggccgccc ggtgcgggtg tagacggctc ctgcggcgcc
    17281 gtcggtcacg ccgaagcggg ccgcggcggc ctcgggcgtc ctggcgagca cggcgacggc
    17341 gcgcgagccc atgtgcttct cctcgcacac gacctcgcgc accccggccg cggcgaactc
    17401 ctcgaacgcc tcgtgcgggt gctccaggta gccgtccagg gtggacgtcc gcggcggcgc
    17461 catggtcggc ggcaggtaga ccagccagcg cggatcgacc gcgaaccgac tcatcacctc
    17521 cagcgcggcg gcggcgttct cctcggcgat cttgaatcgg ccgccgtacc tggtctcgac
    17581 gtgccgggtc ccggcgacgt cgccgatgtc gagcacggtc gagccgcgcg ccgccgcgtc
    17641 gcgggccggc ccgccgagcg gcttgaccgg ctcgtaccag gtcttctccg ctcgcacctg
    17701 gacgatctcc cgctcggggt agcgcagcgc cgtcaggtgg ccgccgaaca cgcagccggt
    17761 gtcgaggcag atcgtgttgt tgacccagac gggggtgtcc gtgggcgtgt ggccgtagac
    17821 gaccgtcgcc cggccgcggt actcctcggc ccacggcagg cgcaccggca ggccgtactc
    17881 gtcggtctcg cccgtggtgt cgccgtacag ggcgaacgag cgcacccggc cggaggcccg
    17941 cccgtggtac ggctccttca gcccggcgtg cgcgacgacc agcctgccgc cgtcgagctg
    18001 gtagtggctg atcaggccgt ccatgaaggc cctggcccgc gccacgaact ccggcggttc
    18061 ggccgcgagc tggtcgagcg actcctgcag gccgtgcgcg accctgacct tgcgcccgtc
    18121 gagggcgcgg gacagcttca cctcgtggtt gccggccacg cacagcgcgg tgcccgcctc
    18181 gaccatgtcc atgaccagcc ggagcacgcc cggcgtgtcg ggcccgcggt ccaccaggtc
    18241 gcccacgaac acggcggtgc ggccctcggg gtggctcagg ccgcgccagc ccagcttgcg
    18301 cagcagcgcc tccagctccg acctgcagcc gtgcacgtcg ccgatgacgt cgaacgggcc
    18361 cgtcagctcc cgcctgtcgg tccacgcctt ctcgtacgcg accccggcgg cctcgatctc
    18421 ctcgacgccg cgcaggacgt gcacccgcct gaacccctcc ttggcgatgc ggcccaggga
    18481 gcggcgcagg tccttgcgct gcctgatgac gacgccaggg ccgaagtcgc ggtcggggcg
    18541 gtcggcgttg cgggcgatcg ccacctcctc gggaacgtcg agcacgacgg cgtcgaccag
    18601 gacgtcgtgg ctcctcgcca gctcgaccaa gctcttcctg gcctggtact gcacgttcgt
    18661 ggcgtcgacc acggtgagca ggcccctgga caggcgcacg ccgacgatgt ggtgcagcag
    18721 gtcgaacgcg gcgggcgtgg ccgcctggtc gttctcgtcg tcggagacga ggcccctgca
    18781 gaagtcggac gagacgacct gcgtcggctt gaagtgcctg gcggcgaacg tggacttgcc
    18841 gctgcccgac acgccgacga gcacgacgag ggagagctca ggaacgctga tcacgggtga
    18901 acactcccat ctgggtgggc gggccgacct cggggtcgtc gtcgcccaca gggcggaacg
    18961 cgacctcgta gccgtgctcg gcggccacgc gggcggccca ggcggcgaac tcggcgcggg
    19021 tccactcgaa gcggtggtcg gggtggcgca gcccggtgag gaacgggtag cggacgttgt
    19081 actcgacgtt cggggtggtc acgacgacgt gcgcgggccg ggcatggccg aacacgacgt
    19141 gctcgagcgc ggccaggcgc ggcgggtcga cgtgctcgac cacctccatg agcaccgccg
    19201 cgtcgtagcc gcgcaggcgc ttgtcggtgt aggtgagcga cccctggaac agggtgagcc
    19261 tggccctgac ggcgtcgggc atccggtcga ggcgcagcct tcgcgcggcg atggtgagcg
    19321 ccatggacga cacgtccatc ccggccacgc gggcgaaacg gggcctcgcc agcagcgcgg
    19381 cgacgagctc gccctgcccg cagccgaggt cggcgacgga gacggcgccg agttcctcca
    19441 gcacgccgag cacggcctcg cgccgcagca cgctgagcga ccgcggcttc ctctcctggc
    19501 cgggctcgcc ctcggcgggt gccccggccg cgccctcggc ggcggtctcg gcggcggctg
    19561 cctcgtcggc ggccgtctcc tccggggacg cctcctccgc gaccggcggc tccagctcct
    19621 cctcggtctc gtcgcccagc tcggccagcc tggccagcgc cgtacgggcc agcgaccagc
    19681 gccgccccag gtacctgcgg gtgatcaggc cgcgctcggg gtggccgccc agccagccct
    19741 cccccgctct gaccagcttg tccacctcgt cgggcgcgat ccagtagtgc ttgccgtcgt
    19801 ccagcacggg cagcagcacg tacaggtggt tgagggcgtc ggacaggcgg agcgtgccgg
    19861 cgagcgcgag ccggacgtaa cgcgactcgc cccaggcggg gaagccctcg tcgagcggca
    19921 cggactccgc cgacacctgc cagccgagcg gcgcgaacag ccgctcggcc agctcggggc
    19981 cgcccctgca gggcagcgcg ggcaggcgga tctccagcgg cagcgccgtg cccggcagct
    20041 ccggcctggc cgcgcaccgg ccggcgcggg ccgtgcggaa cacgtccgcg agcgccaccg
    20101 cgagcagcga cgacgccgcg tagggacggt cgttgacgta ctgcgagagg ctgaagtcgg
    20161 gcgagttcct gcctcgcgac ctgaccagcg cgaccgggtc gacctccagc aggagcgccg
    20221 ccgtgcagcg gtcctcaccg gcctccgggt agaacaccgt ggccgtgccg tacgacccgc
    20281 cgaactcctg cacgcgctcg gggtgcttgt gcaggaggaa cccgaggtcg gtcgccggcc
    20341 tggaggtcgt ggtgatcgtc agcagcacgt cacaagtctg cccgagaccg gacgaacgcc
    20401 gccaaggaat tacctaggcg gccgatcaac ctctgcggaa tggcccggcg gccggtcaga
    20461 cgtgcggcag cacctcggcg gcgatgagct ccaggtgctc ggtgtcggcc aggtcgagga
    20521 tctggaggta gatccgctcg gcacccagct cgccgaacgc tccgatcttc tccaccacct
    20581 cggccggggt gccgcacagg ccgccctcgc gcagcctggc cgggtcctcg ccgatggcct
    20641 cggcccgccg ccgcacctcg gcctcgtcgc ggcccaccac cgtcgtctgc gccgccgaca
    20701 ggaccacgga gcgccctgcc tcctcggtcg ccgcccgcac ccggtcgtag gcggcgcccg
    20761 tctcctcgac ggtcctgaac ggcacgttgt actcgtccgc gtacgccgcg accaggcggg
    20821 gcgtgcgcct ggcgccgatg ccgccgatga tcagcggcgg gcggggccgc tgcgccggct
    20881 tgggcagcgc gggcgagtcg acgagccggt agtagctgcc ctcgaagttg taggtcttct
    20941 ccgcggtcca caggccggtg acgatctcaa gctgctcctc gaaccggtgg aaccgctccc
    21001 cgacgggcgg gaacgggatg ccgtaggcgg cgtgctcggt gtcgaaccag cccgtgccga
    21061 agccc
//
