LOCUS       NZ_BBZG01000001        22562 bp    DNA     linear   CON 12-AUG-2024
DEFINITION  Nonomuraea pusilla strain NBRC 110462, whole genome shotgun
            sequence.
ACCESSION   NZ_BBZG01000001
VERSION     NZ_BBZG01000001.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Nonomuraea pusilla
  ORGANISM  Nonomuraea pusilla
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1
  AUTHORS   Komaki,H., Ichikawa,N., Hosoyama,A., Fujita,N. and Igarashi,Y.
  TITLE     Draft Genome Sequence of Nonomuraea sp. TP-A0861, a Producer of
            Myxochelin A
  JOURNAL   Genome Announc 3 (6), e01430-15 (2015)
   PUBMED   26659677
  REMARK    DOI:10.1128/genomeA.01430-15 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3746196)
  AUTHORS   Hosoyama,A., Kimura,A., Ichikawa,N. and Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2015) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, Biological
            Resource Center (NBRC); 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.8
            Genome Coverage                   :: 107x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001417755.1-RS_2024_08_12
            Annotation Date                   :: 08/12/2024 01:46:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,307
            CDSs (total)                      :: 8,242
            Genes (coding)                    :: 8,159
            CDSs (with protein)               :: 8,159
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1 (5S, 16S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 21 of 83
            Pseudo Genes (incomplete)         :: 72 of 83
            Pseudo Genes (internal stop)      :: 5 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:25:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2709138
            Orig. end                         :: 2731700
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBZG01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22562
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="11"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22562
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22562
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12562](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12562)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(475..1023)
                     /locus_tag="ASC57_RS11970"
     CDS             complement(475..1023)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540300.1"
                     /locus_tag="ASC57_RS11970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DinB family protein"
                     /protein_id="WP_055502899.1"
                     /transl_table=11
                     /translation="MDGNNEPVLREPPVAGDEADTLLGSLERQRRTLAWKCGGVDADGL
                     RATVGASAVTLGGLLRHLALVEDEMFSQRLLGNDPAPPLTAPAGAGPGWEWRLTADDTP
                     ERLMALWEEAVARSRANVRQALEAGGLGGASAYTSSCGETPSLRRLLIDMVEEYARHVG
                     HADLIRESVDGLVGEDPPW"
     gene            1312..1476
                     /locus_tag="ASC57_RS43775"
     CDS             1312..1476
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC57_RS43775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_176573331.1"
                     /transl_table=11
                     /translation="MALACYGVGGLVGGLVTMAWRPRAVGVLAMVAMSLYAVAPLSLAR
                     RRWWGRWPG"
     gene            complement(1587..3833)
                     /gene="katG"
                     /locus_tag="ASC57_RS11975"
     CDS             complement(1587..3833)
                     /EC_number="1.11.1.21"
                     /GO_function="GO:0004096 - catalase activity [Evidence
                     IEA]"
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="katG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654028.1"
                     /locus_tag="ASC57_RS11975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="catalase/peroxidase HPI"
                     /protein_id="WP_055502900.1"
                     /transl_table=11
                     /translation="MSENHDAIVTDAKTETAASTESGGCPVAHGRAAHPTQGGGNRQWW
                     PERLNLKILAKNPAVANPLGEDFDYAEAFRTLDLPAVKRDIAEVLTTSQDWWPADFGHY
                     GPFIIRMAWHSAGTYRISDGRGGAGAGQQRFAPLNSWPDNANLDKARRLLWPVKKKYGK
                     KLSWADLLVLAGNVALESMGFRTFGFGGGRADVWEPDEDVYWGPETTWLGDQRYTGDRD
                     LENPLAAVQMGLIYVNPEGPNGTPDPLAAARDIRETFRRMAMNDEETVALIAGGHTFGK
                     THGAGPADHVGPDPEASPIEQQGLGWKSTYGTGKGGDTITSGLEGIWTPTPVTWDNSFF
                     ETLFGYEWELFKSPAGAWQWKPKDDAGAGTVPDAHDPSKRHAPTMLTTDLSLRVDPVYE
                     QISRRFLENPDEFADAFARAWFKLTHRDMGPVARYLGPEVPSEVLLWQDPLPERTYELI
                     DAEDVAALKSQVLASGLTVSQLVSTAWASAASFRGSDKRGGANGARIRLEPQSGWEVND
                     PDQLAIVLGALEGIQKSFNGAQTGGKQVSLADVIVLAGCAAVEQAARQAGFEVEVPFTP
                     GRVDASQEQTDVESFAVLEPAADGFRNYLGKGSRLPAEYLLIDKANLLTLSAPELTVLV
                     GGLRVLGANHRQSQLGVLTTTPGALTNDFFVNLLDLGTTWQPVSGDEDTFEGRDAATGE
                     LRWTGSRVDLVFGANSELRAVAEVYASDDAKEKFVKDFVAAWDKVMNLDRFDLA"
     gene            complement(3866..4303)
                     /locus_tag="ASC57_RS11980"
     CDS             complement(3866..4303)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1266: hydrogen
                     peroxide sensitive repressor"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852290.1"
                     /locus_tag="ASC57_RS11980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Fur family transcriptional regulator"
                     /protein_id="WP_055502901.1"
                     /transl_table=11
                     /translation="MTPPGTPTIAEELRGAGLRVTAARVALLETIREGDHLDAEAIASG
                     VRDRVGHISLQAVYEALHALTAAGLVRRIEPSGSPARFEGRVGDNHHHLVCRSCGVVAD
                     VDCAVGEAPCLSASDDHGFAIDEAEVIYWGVCPACSTDRSS"
     misc_feature    4467..4482
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.78"
                     /tool="antismash"
     gene            4482..6524
                     /locus_tag="ASC57_RS11985"
     CDS             4482..6524
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544047.1"
                     /locus_tag="ASC57_RS11985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="CehA/McbA family metallohydrolase"
                     /protein_id="WP_055502902.1"
                     /transl_table=11
                     /translation="MCHDESSHDSLLPEPVARALDEYRALRDRHGPCWGEPPIGYVVQA
                     WATVFLDRRHSFYQAGLRQLAERHPGASHGELEDRLGEVDAHRGVRDALGGDVPDNLPV
                     LRLTPGGAALEAHTRVVLGDEPFRTALLLDSSRDEPVTVLVDGAAHEVPPGGAQVVEVT
                     REVVADGRPVDLSPLARRATGAAIRLKAGFPCRWSVTGANGQGWYPDGAPPKVDALRRP
                     YFHGDDVVLVVPAEEITVTVTRGMEYAEATRTLVPAPGEETVVELTPERLYDGAARGWY
                     GGDLHVHLNWMGEEPAAPALAAITQHGEDLHVLNLVAGNVSGERVYDREALEHWVGRDL
                     PWSDERHLARIGVEYRNDVVGHLTAFGLNGLPGRFHSGFAGSPDWPPNAVACEELRALG
                     GTTGYGHPFHTAFGEDDPPDVALDRGRNCSAREIVADAALGLIDTLDVLNHSSIAATAA
                     VYHRLIGAGNRLSVTAGTDVVLSFCRRLSAAAPPGWARVYARVDGPLTTAAYAEAVRLG
                     RTFATTGPWLELTVNGHGPGDSLDLAPGEEVEITVASAGPEVETLEIRTADGVLAQGPP
                     HRLTARLTLDRPTYVVAVATGGPHPRSQHRMGAYAQTSPVYLDVAGEHVVREADVRWCL
                     AWLDRLETILAESGRFETKEQYADHLALYDRARQVYRARLAALGR"
     gene            complement(6628..7692)
                     /locus_tag="ASC57_RS11990"
     CDS             complement(6628..7692)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893852.1"
                     /locus_tag="ASC57_RS11990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_055502903.1"
                     /sec_met_domain="PF04055 (E-value: 1.1e-17, bitscore: 62.5,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 5.2e-06, bitscore: 24.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 8.1e-06, bitscore: 23.1,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIPDRPLEIIWDVTYACPLRCSHCYSESGRRPTRQLDREQLLRV
                     TDAILAMEPYGVSIAGGEPLVVPGIVEVAERMTAAGTRVSLFTSGWPLRAEMIDDVARA
                     FSSVSVSLDGATAEVHDRIRGRRGSFERALRALELLDEAARERRLGGRERLSFGIDCVV
                     VRSNVHQVEDVCAAVAPRFPDLGSISFGAVVPEGLASRAGFVEHELLSDDQAALLGSAG
                     YVARLRALAPPSVQVSATDNLALQMHPDRIRKGSLFPVLQIEPDGAVRAMAAYEGTVGN
                     VLTDSPAELWRRAVERWHDPFVVGTLAPVRTMREWAEATRKIDYHFGSDADRARIDRRP
                     EFGPAGLDSGSARR"
     gene            complement(7796..9658)
                     /locus_tag="ASC57_RS11995"
     CDS             complement(7796..9658)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893853.1"
                     /locus_tag="ASC57_RS11995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_201784509.1"
                     /transl_table=11
                     /translation="MDTQRDQSDAPAAGVTAEPRVPGPDRPAAAQADTQEAGMDGPPGP
                     APTWRVLLRHMRPSWRWLVLGGLLNLTAGAVGLALPLAAKRLLDDLGADRPLAGALALM
                     GVLVVVTAGVGPLGEYVLRRTGETIVLTARRRLVSHLLRLRMSAVDHAEPGDLMSRVTS
                     DTALLRQVTTDSLVGVVTGSVTVLATVTMMGVLDPVLLAVTLGVLVLAGTVVRVAMPRL
                     SRASKEVQKAVGRMSAVLERTLGALRTVKASGAEHREEAALHGAAEGAWRAGVRAAKWL
                     AVAGHTAELALQVAFFTVLAVGGARVTSGTIGVGTLVAFLMYVYYLVPPLQQLVGAAGQ
                     YQIGAAAVARMREAERLPAEPAAPPAALPQPGAAPARLEFRDVRFRYTPGLPFVHRGVT
                     FTVPPRGMTAFVGPSGAGKTTVFSLIERFYDPTSGSILLDGRDLARWDIPSLRSAIGYV
                     EQDAPVLSGSLRDNLVLGAPDTTERDLTRVLRVARLDGLVARLPEGLDTPVGHRGTKLS
                     GGERQRVAIARALLRRPRLLLLDEATSQLDAVNEAALRDTVVEVARTTTVLVVAHRLST
                     VTLADRIVVLDAGTVQAVGTHAELVASDPLYAELAATQFLTAAP"
     gene            complement(10001..12562)
                     /gene="lanKC"
                     /locus_tag="ASC57_RS12000"
     CDS             complement(10001..12562)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038151.1"
                     /locus_tag="ASC57_RS12000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_055502905.1"
                     /sec_met_domain="micKC (E-value: 1.4e-229, bitscore: 762.0,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.5e-13, bitscore:
                     46.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKETLPQLVAYCQADPLFFEPVWRIPDDDNRFPTARRPLPSGWRV
                     GESELWVVMLPPDVALPEQGWKIHVSATDADAGAVCDLVVDFCVERNIAVKFLRSRMAV
                     RLLNNKYADRGSSGKLLTLYPVDEGQLSEVLPLLADLLRGFTGPYVLSDLRYEDSPVYV
                     RYGAFQPITYTRSDGGLGYALRAPDGRLVPDQRTPAFTVPEWVTVPEVLRASVDKRGSG
                     EEGEFPYQIEKALHFSNGGGVYLARDAASGGYVVLLEARPHAGLDTGGTDAVARLAHER
                     DMLERLSGLDCVPRLLDHRVIWEHHFLVEEYVEGRTLLDEVFERYPLTSPDPGPEVLAA
                     YTDWATGVLAEVDHALMSVHARGVRLADLHPENIIVRPDGRVVLIDFEISSDLADTRPP
                     GLAAAGFAAPRDVSGRDADHYVLNCLRQWMFLPISPLQERDPVKLASLTDVITEHFPLP
                     PGFGKRVVRQFEKVRGPLGEDGPARMFTAEEFDWPAVRDSIVAGINASATPDRKDRLFP
                     GDPQQFATGGFTVANGAAGVLWALRQAGADVPSAYVDWLVEAARRAVDPRPGLLNGLHG
                     VAATLESLGRRDDALDLLDRARKLHDGLDVPGVHGGLAGVGLNLLHFSGLTGDEDLRTE
                     ALNVGERLAAELGDGGSAMFPAEGRVGLQHGLTGVAAYFLALHRVTGDERHLDLARLAL
                     QREIARGQVLPDGGFCLLESNRYLAYLGGGSGGLALVLSQYLGLRDEPGFADVVEGVRR
                     ACRAVFTRHPALLMGRAGTIATLHLLGLEEDRPVILDHVRRLSWHALSYQGHLAFPGNQ
                     LMRLSMDVETGSAGVLAALGVVFGQNASILPVLDLRTPQAS"
     gene            complement(12625..14277)
                     /locus_tag="ASC57_RS12005"
     CDS             complement(12625..14277)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="ASC57_RS12005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_055502906.1"
                     /sec_met_domain="p450 (E-value: 1.3e-17, bitscore: 61.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEVSTRDAADRAVVVLGAEAAAPGLAGEFAGRGWRVWTVRISAD
                     AGADAHDGVDQIIDFLAAPESPHRAVLLGGRAAGAAAVEVADRHPERVIAVVVAGDAHG
                     EGPVPGAGVPDPPCPVLVLHTADPGEVVSATTTLLAGSGRRDDVPAPSPARLQALTPTR
                     LNDPEALRRLRELGPVHPVNAAGVTASWIVTGHQATTALLADPRLIGEVEITAGFRLQS
                     DDPALAHRGELDLITISGQEHARLRRLAERHLTPERVEGLRPRVQREVDALLDAVPSRE
                     VVDLLQAFAYPVPVIVLCELLGVPAKDRDYLHEWIVERLASPPPKAHGDIDDYLRGLIA
                     ARRERPSADLLGWVVEAEGDRLREEDLVSLARFLMVNGHRAPTTMLASSVAALLRRRER
                     WERLVADPALVPTAVEELLRVITPFPVTIARHVAVPIEAGGRRLPEGDLLVASLVAANR
                     DPSFFTDPDVLDIGREDNPHLAFGHGHHHCLGAELARAQLQIALGTLVRRFPGMELARD
                     SGSLHYRQSSVRYLLGLPVVLEPDRPRPVSAGA"
     gene            complement(14645..15406)
                     /locus_tag="ASC57_RS12010"
     CDS             complement(14645..15406)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1260: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017543604.1"
                     /locus_tag="ASC57_RS12010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_055502907.1"
                     /transl_table=11
                     /translation="MRNVQLDDVDRVARAVLPIGTDYASGQVLDWHRHRRAQFLYGATG
                     VMIVETDDETWMVPTDRAVLIPAGTRHRVTMLDVSTRSLYIEPDAVPWWPRRCAVVDVT
                     PLLRELLLVAVDFAAEYDLAGREGAVAALLLHEITRLSPVPLHVGLPSSPDLAGLCRAY
                     LADPDVQVTNETWARRLAMSERAFTRRFRREAGISPAAWRTRARLVASVPLLRTSTVTQ
                     VASRLGYSSPASFTAAFSRAFGFAPSTLPRS"
     gene            15493..16317
                     /locus_tag="ASC57_RS12015"
     CDS             15493..16317
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017608767.1"
                     /locus_tag="ASC57_RS12015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_055504006.1"
                     /transl_table=11
                     /translation="MTVLVLAGIGLLTGLTTVLFGFGGGFVTVPVIVWADARLGADAAH
                     VAVATSAVVMIVNAFTATVATDRAVLRLLRRSGTLPAFLAVGGAAGALATRWTPASVTQ
                     WAFVAYLVVTIADVLLRPGFLHRPAGRTAAASAPGAAAGRIRAPLGVPIGVAASFLGVG
                     GSVMTVPLLRRLGHDMRTATALANPLTLAIAAPALVLFFGENARTPASAGVLLWGPVDL
                     GAAAALLAGALPVIVVMRRRPPRIPDKLHAWSYLALLVLVTTAMIGLSLGRT"
     gene            16363..16884
                     /locus_tag="ASC57_RS12020"
     CDS             16363..16884
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019829.4"
                     /locus_tag="ASC57_RS12020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PaaX family transcriptional regulator C-terminal
                     domain-containing protein"
                     /protein_id="WP_055502908.1"
                     /transl_table=11
                     /translation="MGLGVGFVTHAFRQDAALAPWDGAWHLIAFAVPESARAGRDALRA
                     ALTFLGGAAVHGGLYLSPDPWEPYVIAGRYDRLAAVAEPRLRALKDHPEQLEPRRLTIA
                     VEPAAEFTRAMEADPLLPPELLPRPWSGARARTLTARCWSLLEERTGEDDGDIRLFSLY
                     GGLSRLAAGA"
     gene            complement(16978..17823)
                     /locus_tag="ASC57_RS12025"
     CDS             complement(16978..17823)
                     /NRPS_PKS="Domain: Abhydrolase_1 (28-267). E-value:
                     1.3e-23. Score: 75.9. Matches aSDomain:
                     nrpspksdomains_ASC57_RS12025_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="ASC57_RS12025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_055502909.1"
                     /sec_met_domain="PF00561 (E-value: 4.6e-19, bitscore: 66.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 7.9e-25, bitscore:
                     86.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLHAKDIARTVQTEDWKLRYYEAGSGHPVVLLHGSGPGATGWSN
                     FAGNIEALAEHFHVHAVDMPGWGESDPATVDRLDHVEAAIQFLDALGIDRAAFVGNSMG
                     GQTSLRLATEHPGRISHLVTMGPPVGRTPTLFGAGDGPSEGLKVLIEAYRDASPENMRR
                     LVEIMVYDKARFATPELCRARSDAALARPDHLRNYVDGLPKGAPLPKWVKPELLPAIQV
                     PTLLIHGRDDRVVSFETSLYLLANIPNSRLVLLNRCGHWAMIEHADEFNRLVADFIANN
                     "
     aSDomain        complement(17023..17739)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASC57_RS12025_Abhydrolase_1.1"
                     /evalue="1.30E-23"
                     /label="ASC57_RS12025_Abhydrolase_1.1"
                     /locus_tag="ASC57_RS12025"
                     /protein_end="267"
                     /protein_start="28"
                     /score="75.9"
                     /tool="antismash"
                     /translation="PVVLLHGSGPGATGWSNFAGNIEALAEHFHVHAVDMPGWGESDPA
                     TVDRLDHVEAAIQFLDALGIDRAAFVGNSMGGQTSLRLATEHPGRISHLVTMGPPVGRT
                     PTLFGAGDGPSEGLKVLIEAYRDASPENMRRLVEIMVYDKARFATPELCRARSDAALAR
                     PDHLRNYVDGLPKGAPLPKWVKPELLPAIQVPTLLIHGRDDRVVSFETSLYLLANIPNS
                     RLVLLNRCGHWAMIEHA"
     gene            complement(17820..18755)
                     /locus_tag="ASC57_RS12030"
     CDS             complement(17820..18755)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009078334.1"
                     /locus_tag="ASC57_RS12030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VOC family protein"
                     /protein_id="WP_055502910.1"
                     /transl_table=11
                     /translation="MSGVKELGYVVYEVGDLADWEHFAVELLGMQFGEKTDGGFTLRTD
                     EKAHRWIVTAGPADDLVATGYEVSDAAALDALVEKLRAAGVEVTEGDDALAAARKVERI
                     FVTADPMGNRVELVTGLADAATPFESAKLLGRFVTGAGGAGHQVLLAHGVPRETYLRFY
                     IDLLGFKVSDVIVEELAPGVVADLIFLHCNGRHHTVAFGDLPSPKRTHHFMAEVTDIRD
                     VGLAFDRCMDAGRPFEMTLGMHPNDHMFSFYVFTPSGFSVEYGWGGLVIDDETWEVRTL
                     DRLHSWGHRPPGVVAELLAAAPATSGEGDR"
     gene            complement(18784..20328)
                     /locus_tag="ASC57_RS12035"
     CDS             complement(18784..20328)
                     /EC_number="1.14.13.127"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009078333.1"
                     /locus_tag="ASC57_RS12035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="bifunctional
                     3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid
                     hydroxylase"
                     /protein_id="WP_055502911.1"
                     /transl_table=11
                     /translation="MTESYDADVAIVGYGPTGVIAALTLARYGVSAVALERDKDIYPRA
                     RAVTVNDWTMRIFQDLGVDERIEKKIDPQRALRWVTYGGTEIMRVEHPPSTLGRRPRFY
                     NIYQPTMEAELRAAAREHGDRVAVRYGAEVTGIDQDADGVTVTSTDTATGETRTTRTRY
                     AIGADGGSSTIRGEVGCRLLGDTNDVTWVVIDCRVKRWWPDRDFLTFWSDKERPVVDIA
                     LSAGNHRWEIPLKPDESPESYPTSAEVWPLLKAIGVTEEDVEIHQHAFYKHHTRMADTW
                     REGRVFLAGDAAHLMPPWAGAGMQTGMRDAHNLCWKLARVIKGELPESWLDTYEAERRP
                     NAAFYTGLAVELGRVIKQELSEEEQAAMNVVPQDTVTPFEPPLIAPPVLEGGWIRGPLG
                     DASIVGRMVPQPTAGDAVGRMARLDDLLGDGFVLLGDDVDPATLLTAEEKAGWDALGAR
                     YVPVRPKTAYTRGPDELVDLDEVLLPWLRRYGARAVALRPDRFVAAADVSGLAVPA"
     misc_feature    20368..20381
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.04"
                     /tool="antismash"
     misc_feature    20374..20387
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.73"
                     /tool="antismash"
     misc_feature    complement(20395..20410)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.7"
                     /tool="antismash"
     misc_feature    complement(20424..20439)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.28"
                     /tool="antismash"
     gene            20516..21166
                     /locus_tag="ASC57_RS12040"
     CDS             20516..21166
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.4"
                     /locus_tag="ASC57_RS12040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_201784511.1"
                     /transl_table=11
                     /translation="MDKPAPEAHTGNRRGRRSRQEILDAAARVMSVRGYAGTSISTLVK
                     ETGLPKSAFYHHFESKAGLLSAVMAQGAQGFFQAMREAHRDPPAGGTPRERLGWYLRRT
                     GEVFMHHEEFLRLLLVLVMSNEAAEAPEAMRTVIAVRGEGRDHMRHMIRSSFASEGEDA
                     ANAVADALAHFGMAGFDGAFVSLQSGDAKPISEFMEQLADAMVAMGEALIAAR"
     gene            complement(21191..22216)
                     /gene="dmpG"
                     /locus_tag="ASC57_RS12045"
     CDS             complement(21191..22216)
                     /EC_number="4.1.3.39"
                     /GO_function="GO:0008701 - 4-hydroxy-2-oxovalerate aldolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009056 - catabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dmpG"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012850917.1"
                     /locus_tag="ASC57_RS12045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="WP_055502913.1"
                     /sec_met_domain="HMGL-like (E-value: 4.6e-60, bitscore:
                     201.1, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTPIFVQDVTLRDGMHAVRHRISTEDVKRIVAALDRAGVDAIEV
                     AHGDGLAGGSLTYGPGSHTDWEWIEAAASVLVNARLTTLLLPGVGTVHELKRAHDLGVR
                     SVRVATHCTEADISAQHIAAARELGMDVSGFLMLSHMAPPEELARQAKLMESYGAHCVY
                     VTDSGGRLTMNDVAARVRAYRDVLDAGTEIGIHAHENLSLSVANSVVAVENGVHRVDAS
                     LAGHGAGAGNCPLEAFVAVADLSGFEHRCDLFQLQDAADDIVRPLQDRPVRVDRETLTL
                     GYAGVYSSFLRHAEAAAARYGVDVRDILMECGRRRLVGGQEDMIVDIALTMAAEREKRP
                     A"
     misc_feature    22175..22188
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.53"
                     /tool="antismash"
     misc_feature    complement(22176..22189)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 21.65"
                     /tool="antismash"
ORIGIN
        1 agacgctgct gtacggcgag cgctactccg ccacgagcct gcaggcggcg cgccgcatcc
       61 ccgacttcgt gaagctcgcg gacgcctacg gctgcgtcgg gctgcggtgc gagcaccccg
      121 aggacgtcga cgcgaccatc aggagggcca tggagatcga cgacgtgccc gtggtggtcg
      181 acttcgtcgt ccacgagaac gccatggtgt ggcccatggt gcccgcgggc accagcaacg
      241 acgacatcag gtacgcccgc gacatggccc ccacctggga caccaccgag tgacaccgga
      301 gccgccccgg cgaacgccct gcggctgccg acgcgcagct cgccccaggt gaaggccagg
      361 acgccccgac gaggccgctg gtggagcggg cctccccgga gatcgcccgc aggtcgtccc
      421 aggacgcctg gtcggccggg acgatcacga gccggtcctc ggagactccg ggcgtcacca
      481 tggcgggtcc tcgccgacca gcccgtcgac cgactcgcgg atgaggtccg cgtggccgac
      541 gtgacgggcg tactcctcga ccatgtcgat cagcaggcga cggaggctgg gcgtctcgcc
      601 gcacgaggag gtgtacgcgg acgcgccacc gaggccgccc gcctccagcg cctgccgcac
      661 gttggctcgg gagcgggcca cggcctcctc ccagagcgcc atgagccgtt cgggcgtgtc
      721 gtcggccgtg aggcgccact cccagccggg accggcgccg gcgggcgccg tgagcggcgg
      781 cgccgggtcg ttcccgagca ggcgctgcga gaacatctcg tcctcgacca gggccaggtg
      841 cctgagcagc ccgcccagcg tgaccgccga cgcgccgacc gtcgccctca gcccgtccgc
      901 gtccacgccg ccgcacttcc acgcgagggt cctgcgctgg cgctccagcg acccgagcag
      961 ggtgtccgcc tcatcgcccg cgaccggcgg ctcgcgcagc accggctcgt tgtttccgtc
     1021 catgacgaga aaggctacgg tccgttccgg acgatccgct gcttcctgaa ccccctggcc
     1081 tgccgtcgaa acgccgtccg ccgcgatccg ctccggggtg cgcgcgtcgc ctcggaacac
     1141 cgcaccggct cccgggagca ccgaccgccg tcaccccgtc ccccggaggc cccgtgagac
     1201 tcctcgacct caagacgctc ggcaacagca ggttccggct gatgctgctc agccaggcgg
     1261 cgtccgtcgt gggcgagcag atgctcggcg aggcggctcc cccgtggagt ggtggcactc
     1321 gcctgttacg gggtcggtgg cctcgtcggg gggctggtga cgatggcgtg gcgtccgagg
     1381 gccgtcgggg tgctggcgat ggtcgcgatg tcgctctacg ccgtcgcgcc gctctcgctg
     1441 gcgcgcaggc gctggtgggg ccgctggccc gggtgacgag cgcggagacc gtgctggtga
     1501 cgggcgggtc catggccggt ttcaaaaagc tccagccggg ttcgcggggg cccggccggc
     1561 cggggtgggc cggccgggga gcggggtcag gcgaggtcga accggtcgag gttcatcacc
     1621 ttgtcccacg ccgcgacgaa gtccttcacg aacttctcct tcgcgtcgtc gctcgcgtac
     1681 acctcggcga ccgcgcgcag ctcggagttc gccccgaaga cgaggtccac ccggctgccg
     1741 gtccacctga gctcgcccgt ggcggcgtcg cggccctcga aggtgtcctc gtcgccggac
     1801 accggctgcc acgtcgtgcc caggtcgagc aggttgacga agaagtcgtt cgtcagcgcg
     1861 ccgggggtcg tggtgaggac gccgagctgc gactgcctgt ggttggcgcc gaggacgcgc
     1921 aggccgccga cgaggaccgt cagctcgggc gcgctcaggg tgagcaggtt ggccttgtcg
     1981 atcagcaggt actcggccgg gagccggctg cccttgccca ggtagttgcg gaacccgtcg
     2041 gccgccggct ccagcacggc gaacgactcg acgtccgtct gctcctgcga cgcgtccacg
     2101 cggcccgggg tgaaggggac ctcgacctcg aatcccgcct gcctggcggc ctgctcgacg
     2161 gcggcgcagc cggcgagcac gatcacgtcg gcgagcgaga cctgcttgcc gccggtctgt
     2221 gccccgttga aggacttctg gatgccctcc agggcgccca gcacgatcgc gagctggtcg
     2281 gggtcgttga cctcccagcc gctctgcggt tcgaggcgga tgcgcgcgcc gttggcgccg
     2341 ccgcgcttgt cgctgccgcg gaaggacgcg gccgacgccc acgccgtgga gaccagctgc
     2401 gacaccgtca ggccggaggc gaggacctgg ctcttgagcg cggcgacgtc ctcggcgtcg
     2461 atcagctcgt acgtccgctc ggggaggggg tcctgccaca gcaggacctc ggacggcacc
     2521 tcggggccga ggtagcgggc gaccgggccc atgtcgcggt gggtcagctt gaaccacgcg
     2581 cgcgcgaagg cgtcggcgaa ctcgtcgggg ttctcgagga accgccgcga gatctgctcg
     2641 tagaccgggt cgacgcgcag cgacaggtcg gtggtcagca tcgtcggggc gtgccgcttg
     2701 gacgggtcgt gggcgtcggg cacggtgccg gcccccgcgt cgtccttcgg cttccactgc
     2761 caggcgcccg cggggctctt gaacagctcc cactcgtacc cgaagagggt ctcgaagaag
     2821 gagttgtccc aggtcacggg ggtgggggtc cagatgccct caaggccgct ggtgatcgtg
     2881 tcgccgccct tgccggttcc gtacgtgctc ttccagccga ggccctgctg ctcgatcggg
     2941 gacgcctcgg ggtcggggcc gacgtggtcg gcggggccgg cgccgtgggt cttgccgaag
     3001 gtgtgaccgc ccgcgatgag ggcgacggtc tcctcgtcgt tcatcgccat ccggcggaac
     3061 gtctcacgga tgtcgcgggc ggcggcgagc gggtcggggg tgccgttcgg gccctcgggg
     3121 ttgacgtaga tgaggcccat ctgcacggcg gcgagcgggt tctccaggtc cctgtcgccg
     3181 gtgtagcgct ggtcgccgag ccaggtcgtc tcggggcccc agtagacgtc ctcgtcgggc
     3241 tcccagacgt cggcgcggcc gccgccgaag ccgaacgtcc tgaagcccat ggactccagg
     3301 gcgacgttgc cggcgaggac cagcaggtcg gcccaggaca gcttcttgcc gtacttcttc
     3361 ttgacgggcc acagcaggcg gcgggccttg tcgaggttgg cgttgtcggg ccagctgttg
     3421 agcggggcga agcgctgctg cccggccccg gcgccgccgc ggccgtcgct gatccggtac
     3481 gtgcccgcgc tgtgccaggc catccggatg atgaacgggc cgtagtggcc gaagtcggcc
     3541 ggccaccagt cctgggaggt ggtcagcacc tcggcgatgt cccgcttcac ggccggcagg
     3601 tcgagggtcc tgaacgcctc ggcgtagtcg aagtcctcac cgagggggtt ggccacggcg
     3661 gggttcttgg cgaggatctt caggttgagc cgctcgggcc accactggcg gttgccgccg
     3721 ccctgggtgg ggtgggcggc gcgcccgtgc gcgaccgggc agccgccgct ctctgtgctc
     3781 gcggctgtct ccgtcttcgc gtctgtgacg atggcgtcgt ggttctccga catgggaatc
     3841 cttccggact ggccgatcac gttgctcagg aactgcggtc tgtggaacag gcggggcaga
     3901 cgccccagta gatgacctcg gcctcgtcga tggcgaagcc gtggtcgtcg gacgcgctca
     3961 ggcagggtgc ctcgccgacg gcgcagtcga cgtcggccac gacgccgcac gaccggcaca
     4021 cgaggtggtg gtggttgtcg ccgacgcgcc cctcgaacct ggccgggctg ccggacggtt
     4081 cgatgcgccg cacgaggccc gcggcggtga gcgcgtggag ggcctcgtac acggcttgga
     4141 gcgagatgtg acccacgcgg tcccgcaccc ctgacgcgat cgcctcggcg tcgaggtggt
     4201 caccttccct gatggtctcc agcagcgcga cccgcgccgc cgtcaccctc aggccggcac
     4261 cgcgcagctc ctcggcgatg gtcggggtcc cgggtggggt catggcgcca aacctacctt
     4321 cacaaacacg aacaattcaa gacaacgaat agtacaagtt tacaatctcg acagccgtgg
     4381 agccttccat gccgaccagg agctttcgga taaggccgaa agaccctgac aggacaggac
     4441 gagcgtgcca ccatgagggc accctctcca aggagtgttc gatgtgtcac gatgagtcat
     4501 ctcatgacag cctccttccc gagccggtgg cccgcgccct cgacgagtac cgcgccctgc
     4561 gcgaccgcca cggcccctgc tggggcgagc cgccgatcgg gtacgtcgtc caggcgtggg
     4621 ccacggtgtt cctcgaccgg cgtcacagct tctaccaggc cggtctgagg cagctcgccg
     4681 agcgccaccc gggcgcctcc cacggcgagc tggaggaccg cctgggcgag gtggacgccc
     4741 accgcggggt gcgtgacgcg ctcggcggcg acgttcccga caacctgccc gtgctgcggc
     4801 tgacccccgg gggcgccgcg ctggaggcgc acacccgggt cgtcctcggc gacgagccgt
     4861 tccgcaccgc gctgctgctc gactccagca gggacgaacc ggtcacggtg ctcgtcgacg
     4921 gcgcggcgca cgaggtgccg ccgggcggcg cgcaggtggt ggaggtgacg cgcgaggtcg
     4981 tggcggacgg gcggccggtc gatctgtcgc cgctcgccag gcgcgccacc ggcgccgcga
     5041 tccggctgaa ggccgggttc ccgtgccggt ggagcgtgac gggcgcgaac gggcagggct
     5101 ggtaccccga cggcgcgccg cccaaggtcg acgcgctgcg caggccgtac ttccacggcg
     5161 acgacgtcgt cctcgtggtg cccgccgagg agatcacggt gacggtcacc cgcggcatgg
     5221 agtacgcgga ggcgacccgc acgctcgtcc ccgcgccggg cgaggagacg gtggtcgagc
     5281 tcacccccga gcggctgtac gacggggcgg cgcgcggctg gtacggcggc gacctgcacg
     5341 tccacctcaa ctggatgggc gaggagccgg ccgcgccggc gctcgccgcg atcacccagc
     5401 acggcgagga cctgcacgtt ctcaacctgg tcgcgggcaa cgtgtccggc gagcgcgtct
     5461 acgacaggga ggcgctggag cactgggtcg gccgcgacct gccctggtcc gacgagcggc
     5521 acctggccag gatcggagtc gagtaccgca acgacgtggt cgggcacctc accgcgttcg
     5581 gcctgaacgg gctgccgggc cgcttccaca gcggcttcgc cggctccccc gactggccgc
     5641 cgaacgcggt cgcctgcgag gaactgcgcg ccctcggcgg gacgaccggc tacgggcacc
     5701 cgttccacac cgcgttcggc gaggacgacc cgccggacgt cgcgctcgac cgcgggcgca
     5761 actgctcggc gcgggagatc gtcgccgacg ccgcgctcgg gctgatcgac acgctcgacg
     5821 tgctcaacca ctcctcgatc gccgccacgg cggccgtcta ccaccgcctg atcggcgcgg
     5881 gcaaccggct gtcggtcacc gcgggcacgg acgtggtgct gtccttctgc cgccggttga
     5941 gcgccgccgc cccgcccggc tgggccaggg tgtacgcccg cgtggacggc ccgctcacca
     6001 ccgcggcgta cgcggaggcg gtacggctcg gccgcacgtt cgccaccacc gggccctggc
     6061 tggagctcac cgtgaacggg cacggccccg gcgactccct cgacctcgct cccggcgagg
     6121 aggtggagat cacggtggcc tcggccggcc cggaggtcga gacgctggag atccgcaccg
     6181 cggacggcgt cctcgcgcag gggccgccgc accgcctgac cgcgcggctc accctcgacc
     6241 ggcccacgta cgtggtggcc gtcgccaccg gcgggccgca cccgcgcagc cagcaccgga
     6301 tgggcgcgta cgcgcagacc agccccgtct acctggacgt ggccggcgag cacgtggtca
     6361 gggaggcgga cgtccgctgg tgcctggcct ggctggaccg gctggagacg atcctcgcgg
     6421 agtcgggccg tttcgagacc aaggagcagt acgccgacca tctggccctg tacgaccggg
     6481 ccaggcaggt ctaccgcgcc cggctcgccg ccctcggccg ctgaccggcc ggtcccgccg
     6541 ggcgatccgc cgcccggcgg gctccgccgc tggtgctgac ccgcccgcgg cgctaccgga
     6601 gagagcccgc cgacggagcc ggcggcgtca ccgccgggcg gagccggagt ccaggccggc
     6661 ggggccgaac tccggccggc ggtcgatgcg cgcgcggtcg gcgtccgagc cgaagtggta
     6721 gtcgatcttc cgggtggcct ccgcccactc ccgcatcgtc cgcacgggcg ccagcgtgcc
     6781 gaccacgaac gggtcgtgcc agcgttcgac ggcgcgccgc cagagctccg ccggggagtc
     6841 cgtcagcacg ttgccgaccg tcccctcgta cgccgccatc gcccgtacgg ctccgtccgg
     6901 ctcgatctgc agcacgggga agaggctgcc cttccggatg cgatcggggt gcatctgcag
     6961 cgccaggttg tccgtcgcgc tcacctgcac ggacggcggg gccagggcgc gcaggcgagc
     7021 cacgtacccg gcgctcccca gcagcgcggc ctgatcgtcc gacagcagtt cgtgctccac
     7081 gaacccggca cggctggcga gcccctccgg caccaccgcc ccgaacgaga tcgaccccag
     7141 gtcggggaac ctgggcgcga cggcggcgca gacgtcctcg acctggtgga cgttgctgcg
     7201 gaccaccacg cagtcgatcc cgaaggagag gcgttccctc ccgccgaggc gccgctcccg
     7261 cgcggcctcg tccagcagtt ccaacgcccg cagcgcccgc tcgaacgacc cgcgccgccc
     7321 gcggatccgg tcgtgcacct ccgccgtggc gccgtcgagg ctcacgctca cgctggagaa
     7381 ggcccgcgcg acgtcgtcga tcatctcggc gcgcagcggc cagccgctgg tgaagagcga
     7441 gacccgggtc ccggcggcgg tcatccgctc ggcgacctcg acgatgccgg gcaccacgag
     7501 gggctcgccc cctgcgatgg agacgccgta cggctccatg gcgaggatgg cgtcggtcac
     7561 gcggagcagc tgctcgcggt ccagctggcg ggtcgggcgg cgccccgact ccgaatagca
     7621 gtgggagcac cggagcgggc aggcgtaggt gacatcccag atgatctcga gcggacggtc
     7681 gggtatttcc atggctgcgc tcctggctgc ggaagggggc cggaccggcc ctgaggacgg
     7741 gagaaccggc gacggtctcc ccggacgtgt ccctggccac ccggatcccg gggcgtcagg
     7801 gggcggcggt gaggaactgg gtggcggcga gctcggcgta gagcgggtcg gaggcgacca
     7861 gctccgcatg ggtgccgacg gcctgaacgg tgcccgcgtc caggacgacg atccggtcgg
     7921 ccagcgtgac cgtcgacagc cggtgcgcca cgaccagcac ggtcgtcgtc cgcgcgacct
     7981 cgacgacggt gtcgcgcagg gccgcctcgt tgacggcgtc gagctgcgag gtggcctcgt
     8041 ccaggagcag cagcctgggg cggcgcagca gcgcgcgggc gatggccacg cgctggcgct
     8101 cgccgccgga gagcttggtg ccgcggtggc cgaccggggt gtccaggccc tcgggcagcc
     8161 gggccaccag gccgtcgaga cgggcgaccc gcaggacccg cgtcaggtcg cgctcggtgg
     8221 tgtccggggc gccgagcacg aggttgtcgc ggagggagcc cgacaggacg ggcgcgtcct
     8281 gctcgacgta cccgatggcg gagcgcaggc tcgggatgtc ccagcgggcg aggtcgcggc
     8341 cgtcgaggag gatgctgccc gaggtcgggt cgtagaacct ctcgatgagc gagaagacgg
     8401 tggtcttgcc cgcgccggac ggtccgacga aggcggtcat gcctcgcggc ggaacggtga
     8461 aggtcacccc gcggtgcacg aacggcaggc cgggcgtgta gcggaagcgc acgtcgcgga
     8521 actccagccg cgccggtgcc gcgcccggct gggggagcgc ggccggcggc gccgccggct
     8581 cggccgggag ccgctcggcc tcccgcatcc gggcgaccgc cgccgccccg atctggtact
     8641 ggccggccgc gccgacgagc tgctggagag gcggcaccag gtagtacacg tacatcagga
     8701 acgcgaccag cgtgcccacg ccgatcgtcc ccgaggtcac cctggcgccg cccaccgcga
     8761 gaacggtgaa gaaggccacc tggagggcga gttccgcggt gtgcccggcg accgccagcc
     8821 acttggcggc gcgcacgccg gcccgccacg ccccctcggc ggccccgtgg agtgccgcct
     8881 cctcgcgatg ctcggcgccg gacgccttca cggtgcgcag cgccccgagg gtccgctcca
     8941 ggaccgcgct catgcgcccc accgccttct ggacctcctt gctggcccgg ctcagacgcg
     9001 gcatggccac ccggacgacc gtcccggcca ggaccagcac cccgagcgtg acggcgagca
     9061 gcaccgggtc gagcacgccc atcatcgtca cggtcgccag gaccgtgacg ctcccggtga
     9121 cgacgccgac cagcgagtcg gtcgtgacct ggcggagcag cgcggtgtcg gaggtgaccc
     9181 tggacatcag gtcgccgggt tccgcgtggt cgacggcgga catccgcagc cgcagcaggt
     9241 gggagaccag gcgacggcgg gcggtgagca cgatcgtctc gccggtgcgg cgcagcacgt
     9301 actcgcccag cggaccgacc ccggcggtga ccacgacgag gacgcccatc agcgccagcg
     9361 caccggccag gggccggtcg gcgccgaggt cgtcgagcag ccgcttggcc gcgagcggga
     9421 gcgccagccc gaccgctccg gccgtgaggt tcagcagccc gccgaggacg agccagcgcc
     9481 aggacgggcg catgtgccgc agcagcacgc gccacgtggg cgccgggccg ggcggcccgt
     9541 ccatgcccgc ctcctgcgta tccgcctggg ccgcagcggg ccggtccggg ccggggacgc
     9601 ggggctctgc cgtcaccccc gccgccgggg cgtcggactg gtcgcgctgc gtgtccacgg
     9661 gattcctcgc aagcatgtcg gggccggggt cgggagaggg cgggtgcggt cctccctcgc
     9721 gaccggcccc ggcctgacgc gccgcggcgc gcccggccgg ggccgggtgc cggggacctt
     9781 cgcgggtccc cggcggtgcg tcgtcagacg cagatgtagc aggcggtgcc gttgtaggac
     9841 gtcaccaggc tggagcaggg gtgcgccttg ctctcagcgg tgctcagcgt ctgcagctga
     9901 aggatctgcg ccatttccgg gtttcctttc tgttggctcg cccgcgggga tccgcggccg
     9961 aggtctctgg ctcgcccgcg ggtcggcggg tcgaggtctt tcagctcgcc tgcggggtac
    10021 gcaggtcgag aaccgggagg atcgacgcgt tctggccgaa gacgacgccg agggcggcga
    10081 ggactccggc cgaacccgtc tccacgtcca tggacaaccg catgagctgg ttgccgggga
    10141 aggcgaggtg gccctggtag gagagggcgt gccaggagag ccggcgcacg tggtcgagga
    10201 tcacgggccg gtcctcctcg aggcccagga ggtgcagcgt cgcgatggtg cccgcccggc
    10261 ccatgagcag ggccgggtgc cgggtgaaca ccgcccggca ggcgcgccgg acgccctcga
    10321 cgacgtccgc gaagcccggc tcgtcccgca ggcccaggta ctgggagagc accagggcca
    10381 ggccgccgct gccgccgccg aggtaggcga ggtagcggtt gctctccagc aggcagaagc
    10441 cgccgtccgg cagcacctgg cctcgggcga tctcccgctg cagcgccagc cgggccaggt
    10501 cgaggtgacg ctcgtccccg gtgacgcgat gcagcgcgag gaagtaggcg gcgaccccgg
    10561 tcagtccgtg ctggaggccg acccttccct ccgccgggaa catcgccgac ccgccgtcgc
    10621 cgagctccgc ggccagcctc tcaccgacgt tcagtgcttc ggtgcgcagg tcctcgtccc
    10681 cggtgaggcc ggagaagtgc aggaggttga ggcccacccc ggccaggccg ccgtgcacgc
    10741 cgggcacgtc gaggccgtcg tgcagcttcc gggcgcggtc gagcaggtcg agggcgtcgt
    10801 ccctgcgccc gagcgactcc agggtcgccg ccacgccgtg cagcccgttc agcaggcccg
    10861 gacgcgggtc gacggcccgg cgggcggcct cgacgagcca gtccacgtac gcggacggca
    10921 cgtcggcgcc tgcctgccgc agcgcccaga gcactcccgc ggcgccgttg gccaccgtga
    10981 accctccggt cgcgaactgc tgcgggtcgc cggggaagag ccggtccttg cggtcgggtg
    11041 tcgcgctcgc gttgatcccc gccacgatgg agtcgcgcac ggccggccag tcgaactcct
    11101 cggccgtgaa catccgcgcg ggcccgtcct cgcccagcgg cccccgcacc ttctcgaact
    11161 gccggacgac gcgcttcccg aaccccggcg gcagcgggaa gtgctcggtg atgacgtcgg
    11221 tgaggctggc gagcttcacc gggtcccgct cctgcagcgg gctgatcggg aggaacatcc
    11281 actgccgcag gcagttgagc acgtagtggt cggcgtcacg gccggacacg tcgcgcggcg
    11341 cggcgaaccc cgccgcggcc agacccggag gccgcgtgtc cgccaggtcc gacgagatct
    11401 cgaagtcgat cagcacgacg cgcccgtccg ggcggacgat gatgttctca gggtgcaggt
    11461 ccgccaggcg cacccctctc gcgtggacgg acatgagcgc gtggtcgacc tcggccagga
    11521 cgccggtcgc ccagtcggtg tacgcggcca gcacctcggg gcccggatcg gggctggtca
    11581 gcgggtagcg ctcgaacacc tcgtccagca gggtcctgcc ctcgacgtac tcctccacca
    11641 ggaagtggtg ctcccagatc acccggtggt ccagcaggcg gggtacgcag tcgaggccgc
    11701 tcagccgctc cagcatgtcg cgttcgtgcg ccagccgggc gaccgcgtcg gtgccgcccg
    11761 tgtcgagccc cgcgtgcggc ctggcctcca gcagcaccac gtagccgccg gacgccgcgt
    11821 ccctggcgag gtagaccccg ccgccgttgg agaagtgcag cgccttctcg atctggtacg
    11881 ggaactcccc ctcctcgccc gacccgcgct tgtcgaccga ggcccgcagc acctccggga
    11941 cggtgaccca ttccggcacg gtgaaggcgg gggtccgctg gtccggcacc agccgcccgt
    12001 cgggcgcccg gagcgcgtag cccagtccgc cgtccgacct ggtgtaggtg atcggctgaa
    12061 acgcgccgta ccggacgtag accggcgagt cctcgtaccg gaggtcgctg aggacgtagg
    12121 ggccggtgaa gccgcgcagg aggtcggcca gcagcggcag cacctcgctc agctgcccct
    12181 cgtccaccgg gtacagcgtg agcagcttgc cgctgctccc ccggtcggcg tacttgttgt
    12241 tgagcagccg caccgccatc ctgctcctga ggaacttcac ggcgatgttc cgctcgacgc
    12301 agaagtccac gacgagatcg cagacggcgc ccgcgtcggc gtccgtcgcc gagacgtgga
    12361 tcttccatcc ctgttccggg agcgcgacgt cgggcgggag catcacgacc cacagctcgc
    12421 tctcgccgac gcgccacccg ctcgggagag gacggcgagc ggtggggaac cggttgtcgt
    12481 cgtccggtat gcgccagacc ggctcgaaga acagcggatc ggcctggcag tacgccacca
    12541 gctggggaag cgtctctttc atctggtcgg actcctgagt gccgagagcg ttgagaggga
    12601 tcctgtgggt gccggtctcc ggcgtcaggc gccggctgag accggccggg gacggtccgg
    12661 ttcgaggacg accggcagcc cgaggaggta gcgcacgctg ctctgccggt agtgcaggct
    12721 cccggagtcg cgggcgagct ccatgccggg gaagcgccgt acgagcgtgc cgagcgcgat
    12781 ctgcaactgg gccctcgcca gctccgcccc caggcagtgg tggtgtccgt ggccgaaggc
    12841 caggtgaggg ttgtcctcgc gcccgatgtc cagcacgtcc gggtcggtga agaacgacgg
    12901 gtcgcggttg gcggcgacga gcgacgcgac caggaggtcc ccctcgggga gccgcctgcc
    12961 ccccgcctcg atcgggaccg ccacgtgacg ggcgatggtg accgggaagg gagtgatgac
    13021 gcgcagaagt tcctcgaccg ccgtggggac cagggcggga tcggcgacga ggcgctccca
    13081 ccgctcgcgc cggcgcagca gggccgccac gctgctggcc agcatcgtgg tcggcgcccg
    13141 gtgcccgttc accatcagga acctcgcgag ggagacgagg tcctcctcac gcagccggtc
    13201 cccctccgct tcgacgaccc agccgagcag gtccgccgag ggacgttccc tcctggccgc
    13261 gatcaggccg cgcaggtagt cgtcgatgtc gccgtgcgcc ttgggcggcg gggacgccag
    13321 ccgttccacg atccactcgt gcaggtagtc acggtccttc gccggcacgc ccagcagctc
    13381 gcacagcacg atgaccggga cggggtaggc gaacgcctgc aggaggtcga cgacctcgcg
    13441 tgaggggacc gcgtccagca gcgcgtcgac ctcgcgctgg acgcgcgggc gcagcccttc
    13501 cacccgctcg ggcgtgaggt gccgctcggc cagccggcgc agccgcgcgt gctcctgccc
    13561 gctgatcgtg atcaggtcca gttcgcccct gtgggcgaga gccgggtcgt ccgactggag
    13621 ccggaagccc gcggtgatct ccacctcccc gatcagccgc gggtcggcca gcagcgccgt
    13681 ggtcgcctgg tgcccggtca cgatccacga cgccgtcacg cccgccgcgt tgaccgggtg
    13741 gaccggtccg agctccctca gccgccggag cgcctcgggg tcgttgagcc gcgtgggggt
    13801 gagcgcctgg agccgtgccg gggacggcgc ggggacgtcg tcccgccggc cggatcccgc
    13861 cagcagggtg gtggtcgcgg acaccacctc cccggggtcc gcggtgtgga gcaccagaac
    13921 ggggcagggc ggatccggga cgccggctcc gggaaccggg ccctcgccgt gcgcgtcacc
    13981 ggcgaccacc accgcgatca cgcgctccgg gtggcggtcc gcgacctcca ccgccgccgc
    14041 gccggccgca cggccgccga gcagcacggc gcggtgcggg ctctccggcg ccgccaggaa
    14101 gtcgatgatc tggtcgacgc cgtcgtgggc gtcggcgccg gcgtcggcgg agatcctgac
    14161 ggtccagacc cgccagcccc tgccggcgaa ctcgcccgca agccccgggg ccgccgcctc
    14221 cgcgccgagg acgaccacgg cccggtcggc ggcgtcccgg gtcgaaacct ctgccatccc
    14281 ggcccctccg catgtccaga cagccggaac gcaccgttcg gccttggtga tcaccgtttc
    14341 ccagcaacct tgtgaaggac ttgccggcga ttgcgggcac cttgtggatc accgcccagg
    14401 cgccccgatc cgcgcctcga cctggccctt gacgcgcttc tccgggcgac acggagacga
    14461 cgatcgcgac ggtgagcgac cgcggcgctc gacgctgacg gccgcgtccc gcacttgtga
    14521 acccttgcca cggcccaagg cgatcccgcc cccaaacctg accgggaaag caggatgtga
    14581 cgacaatccg cccacccgtc gccctgggct cctgcgcgcc gccggactga cgccggggtc
    14641 ggatctagct ccggggcagg gtggacgggg cgaagccgaa cgcgcgtgag aaggccgcgg
    14701 tgaacgacgc cggggaggag tagcccaggc ggctcgcgac ctgggtgacg gtggacgtgc
    14761 gcagcagcgg gaccgaggcg acgagccggg cgcgggtccg ccaggcggcc gggctgatgc
    14821 cggcctcgcg gcggaagcga cgggtgaagg cgcgctcgct catggccagg cggcgcgccc
    14881 aggtctcgtt ggtgacctgg acgtccgggt cggcgaggta ggcgcggcag aggccggcca
    14941 ggtccggcga cgagggcagc ccgacgtgga gcggcaccgg gctcaggcgg gtgatctcgt
    15001 gcagcagcag tgccgcgacc gccccctcgc ggccggcgag gtcgtactcg gccgcgaagt
    15061 cgacggcgac gagcagcagc tcgcgcagca gcggggtgac gtccacgacg gcgcacctgc
    15121 gcggccacca gggcacggcg tccggctcga tgtagaggct gcgggtgctg acgtcgagca
    15181 tggtgacgcg gtggcgggtg ccggccggga tgaggacggc gcggtcggtc ggcaccatcc
    15241 acgtctcgtc gtcggtctcg acgatcatca cgcccgtggc gccgtacagg aactgcgcgc
    15301 gccgatgccg gtgccagtcg agcacctgtc ctgaggcgta gtcggtgccg atgggcagca
    15361 cggctctcgc gacccggtcg acgtcgtcga gctgaacgtt ccgcacaggc ggaagcgtag
    15421 tggccgactc tcgaaacatc acgaccggcc ttcgattgtc cgccgcgagg cggcgccggt
    15481 tgactcgtgg tcgtgactgt tctcgtgctg gccgggatcg gcctcctcac cggcctgacc
    15541 accgtgctgt tcggattcgg cggcgggttc gtcaccgttc ccgtcatcgt gtgggccgac
    15601 gcgcggctcg gcgccgacgc ggcccacgtc gcggtcgcca cctccgccgt ggtcatgatc
    15661 gtcaacgcct tcacggcgac cgtcgcgacc gaccgtgccg tcctccgcct gctgcgccgg
    15721 agcgggaccc tgccggcctt cctcgccgtc ggcggtgcgg ccggcgcgct cgcgacccgc
    15781 tggaccccgg cgtccgtgac gcagtgggcc ttcgtcgcct acctggtcgt cacgatcgcc
    15841 gacgtgctcc tgcggcccgg cttcctccac cgcccggctg gacgtacggc cgccgcctcc
    15901 gctccaggag cggcggccgg tcgcatccgg gccccgctgg gcgtgcccat cggcgtggcg
    15961 gcgtcgttcc tcggggtcgg cggcagtgtc atgaccgtcc ccctgcttcg caggctgggc
    16021 cacgacatgc gcaccgccac cgcgctcgcc aacccgctga cgctcgccat cgcggcgccg
    16081 gcgctcgtcc tcttcttcgg tgagaacgcg aggacccccg cgtccgcggg cgtcctcctg
    16141 tggggtccgg tggacctcgg ggccgcggcg gcgctcctgg cgggcgccct gccggtgatc
    16201 gtcgtcatgc gccgccgccc gccccgcatc cccgacaagc tgcacgcgtg gagctacctg
    16261 gcgctcctcg tcctcgtcac caccgcgatg atcggcctct ccctcggccg cacctgacgg
    16321 gggcactgcg tcagtggcga cgatccggct ccagccgggg cgatggggct cggcgtcggg
    16381 ttcgtcaccc acgcgttccg ccaggacgcc gcgctcgccc cctgggacgg cgcctggcac
    16441 ctcatcgcct tcgccgtccc ggagagcgcc cgggccggcc gcgacgcgct gcgcgccgcg
    16501 ctcaccttcc tgggcggcgc cgccgtccac ggggggctct atctcagccc cgatccgtgg
    16561 gagccctacg tcatcgccgg acggtacgac aggctcgccg cggtggcgga gcctcggctc
    16621 cgggccctca aggatcatcc ggagcagttg gagccgcggc ggctgaccat cgcggtggaa
    16681 ccggccgcgg agttcacccg ggcgatggag gccgacccgc tgcttccccc cgaactgctc
    16741 ccccggccct ggtccggcgc gcgggcccgc acgctgaccg cgcgttgctg gtcgctgctg
    16801 gaggagcgga ccggcgagga cgacggcgac atccgcctgt tcagtctcta cggcggcctg
    16861 agccgcctgg cggcgggcgc ctgacccgcc gtcgcaccgc tccatgctga gcacggcgag
    16921 tcggggatcg ccctcgccgc cgtgctccct ggcccggacg gacctgaacc cgccgggtca
    16981 gttgttcgcg atgaagtcgg cgaccagccg gttgaactcg tcggcgtgct cgatcatggc
    17041 ccagtgcccg cagcggttga gcagcaccag ccggctgttc gggatgttcg ccagcaggta
    17101 cagcgaggtc tcgaacgaga cgacgcggtc gtcgcggccg tggatgagca gggtcggcac
    17161 ctggatcgcg ggcagcagct ccggcttgac ccacttcggc aggggggcgc ccttcggcag
    17221 gccgtccacg tagttgcgca ggtggtcggg acgggccagc gcggcatcgg aacgcgcccg
    17281 gcacagctcg ggggtggcga accgggcctt gtcgtagacc atgatctcga cgagccggcg
    17341 catgttctcc gggctcgcgt cgcggtaggc ctcgatcagc accttcaggc cctcggaggg
    17401 gccgtcaccg gcgccgaaga gcgtgggcgt ccggccgacc ggcggcccca tggtgaccag
    17461 gtgggagatc cggccggggt gctccgtcgc gagccgcagc gaggtctggc cgcccatcga
    17521 gttgccgacg aacgccgccc tgtcgatgcc gagggcgtcc aggaactgga tcgccgcctc
    17581 cacgtggtcg agccggtcga cggtcgcggg gtccgactcg ccccagccgg gcatgtcgac
    17641 ggcgtggacg tggaagtgct cggccagcgc ctcgatgttg ccggcgaagt tgctccagcc
    17701 cgtcgcgccc ggtccgctgc cgtgcagcag cacgaccggg tgaccggagc ccgcctcgta
    17761 gtagcggagc ttccagtcct cggtctggac ggtgcgcgcg atgtccttgg cgtggagggt
    17821 catcggtcgc cctccccgct cgtggcgggc gcggcggcca gcagttcggc gacgacgccc
    17881 ggcggacggt ggccccagct gtgcagcctg tcgagcgtcc tcacctccca cgtctcgtcg
    17941 tcgatgacca gcccgcccca gccgtactcg acgctgaagc ccgacggggt gaagacgtag
    18001 aagctgaaca tgtggtcgtt cgggtgcatc ccgagcgtca tctcgaacgg ccgcccggcg
    18061 tccatgcacc ggtcgaaggc caggccgacg tctcggatgt cggtcacctc ggccatgaag
    18121 tgatgggtcc tcttcggcga cggcaggtcg ccgaaggcca cggtgtggtg acggccgttg
    18181 cagtgcagga agatcaggtc ggcgaccacg cccggggcca gttcctcgac gatgacgtcg
    18241 ctgaccttga agccgagcag gtcgatgtag aagcgcaggt aggtctcccg cgggacgccg
    18301 tgcgcgagga ggacctggtg gcccgcgccg ccggcgcccg tcacgaaccg gccgagcagc
    18361 ttcgcggact cgaacggcgt ggcggcgtcg gccaggccgg tgaccagctc gacccggttg
    18421 cccatggggt cggcggtgac gaagatccgc tcgaccttgc gggccgcggc gagggcgtcg
    18481 tcgccctccg tgacctcgac cccggccgcg cggagcttct cgaccagcgc gtcgagcgcg
    18541 gcggcgtccg agacctcgta gccggtggcc accaggtcgt cggcgggccc cgcggtgacg
    18601 atccagcggt gggccttctc gtcggtgcgc agggtgaacc cgccgtcggt cttctcgccg
    18661 aactgcatgc ccagcagctc gacggcgaag tgctcccagt cggcgaggtc gccgacctcg
    18721 tagacgacgt aaccgagttc cttgactccg gacatctctc ttctccttct cgggtaaccg
    18781 gtctcaggcg ggcacggcga ggccgctgac gtcggcggcg gcgacgaacc tgtcggggcg
    18841 gagcgccacg gcgcgggcgc cgtacctgcg cagccacggc aggaggacct cgtcgaggtc
    18901 gaccagctcg tccgggcccc gcgtgtacgc cgtcttcggc cgcaccggga cgtagcgggc
    18961 cccgagcgcg tcccagcccg ccttctcctc cgccgtcagc agggtcgcgg ggtcgacgtc
    19021 gtcgccgagc aggacgaagc cgtcgccgag gaggtcgtcc aggcgcgcca tgcggccgac
    19081 ggcgtcgccg gcggtcggct gcgggaccat ccggccgacg atgctggcgt cgcccagcgg
    19141 ccccctgatc catccgccct cgagcaccgg cggggcgatg agcggcggct cgaacggggt
    19201 gaccgtgtcc tgagggacca cgttcatcgc ggcctgctcc tcctcggaca gttcctgctt
    19261 gatgacccgc ccgagctcga ccgcgagccc cgtgtagaag gcggcgttcg ggcgccgctc
    19321 cgcctcgtag gtgtccagcc agctctcggg cagctcgccc ttgatcacgc gggcgagctt
    19381 ccagcacagg ttgtgggcgt cgcgcatccc ggtctgcatc ccggcgccgg cccacggcgg
    19441 catcaggtgg gccgcgtcac cggccaggaa cacccggccc tcgcgccagg tgtcggccat
    19501 ccgggtgtgg tgcttgtaga aggcgtgctg gtggatctcg acgtcctcct cggtgacgcc
    19561 gatcgccttg agcagcggcc acacctcggc gctggtcggg tagctctcag gggactcgtc
    19621 gggcttgagc gggatctccc atcggtggtt gccggcggag agcgcgatgt cgacgacggg
    19681 ccgctccttg tcggaccaga aggtcaggaa gtcccggtcg ggccaccacc gcttgacgcg
    19741 gcagtcgatg accacccagg tgacgtcgtt ggtgtcgccc agcaggcggc agcccacctc
    19801 gccccggatc gtgctgctgc cgccgtcggc gccgatcgcg tagcgggtgc gggtggtgcg
    19861 ggtctcgccg gtcgcggtgt ccgtcgaggt gacggtgacg ccgtcggcgt cctggtcgat
    19921 gccggtgacc tcggcgccgt agcggacggc gacgcggtcg ccgtgctccc gcgccgccgc
    19981 gcgcagctcg gcctccatcg tcggctggta gatgttgtag aagcgcggcc tgcggcccag
    20041 cgtggagggc gggtgctcga cccgcatgat ctccgttccg ccgtaggtca cccagcggag
    20101 cgcccgctgg gggtcgatct tcttctcgat ccgctcgtcc acgccgaggt cctggaagat
    20161 ccgcatcgtc cagtcgttga cggtcacggc ccgggcccgg ggatagatgt ccttgtcccg
    20221 ctcgagggcg acggcggaga cgccgtacct ggcgagggtg agtgcggcga tcacgccggt
    20281 cgggccgtac ccgacgatcg cgacgtccgc gtcgtagctc tcggtcatgc gctgactccg
    20341 ttctcggccg caggtgctcg atgcggcact tttggaccaa acgttcggtc caatagtgag
    20401 gagggtaaca acgagcagcg gcgacgtgtc aagacctgtc ccggacggag caccccgcca
    20461 ccgcggccgc gccgcgcgga tgagccggcg tctccgggtc cctagacttc ggcaggtgga
    20521 caagcccgcg ccggaggcgc acaccggaaa ccgccgcggc cgccggtcgc gccaggagat
    20581 cctcgacgcg gccgcccggg tgatgtccgt gcgcggctac gccggcacgt cgatctcgac
    20641 gctggtgaag gagacgggcc tgccgaagag cgccttctac caccacttcg agtccaaggc
    20701 ggggctgctc tccgccgtca tggcgcaggg ggcgcagggc ttcttccaag ccatgcgcga
    20761 ggcccaccgc gacccgccgg ccggcggcac cccgcgcgag cgcctggggt ggtacctgcg
    20821 gaggaccggc gaggtcttca tgcaccacga ggagttcctc cggctgctgc tggtcctcgt
    20881 gatgagcaac gaggccgccg aggcgccgga ggcgatgcgg accgtgatcg cggtccgcgg
    20941 cgagggccgc gaccacatgc ggcacatgat ccgctcgtcg ttcgcgagcg agggcgagga
    21001 cgccgcgaac gcggtcgcgg acgccctcgc ccacttcggc atggccgggt tcgacggcgc
    21061 gttcgtctcg ctccagtcgg gggacgccaa gccgatctcc gagttcatgg agcagctcgc
    21121 cgacgccatg gtggcgatgg gcgaggcgct gatcgccgcc cgctgaggcg tcgtcccccg
    21181 gccccgccgg tcaggccggg cgcttctcgc gctcggccgc catcgtgagc gcgatgtcga
    21241 cgatcatgtc ctcctggccg cccaccagcc ggcggcgtcc gcactccatg aggatgtcgc
    21301 ggacgtccac gccgtaccgc gccgcggcgg cctccgcgtg gcgcaggaac gacgagtaga
    21361 cgccggcgta ccccagggtg agggtctccc ggtcgacgcg caccggacgg tcctgcagcg
    21421 ggcggacgat gtcgtccgcg gcgtcctgga gctggaacag gtcgcaccgg tgctcgaagc
    21481 ccgagaggtc cgcgaccgcg acgaacgcct ccagcgggca gttgcccgcg cccgcgccgt
    21541 gaccggccag cgacgcgtcc acccggtgga cgccgttctc gaccgcgacg acggagttgg
    21601 cgaccgacag cgagaggttc tcgtgggcgt ggatgccgat ctcggtcccg gcgtcgagga
    21661 cgtcccggta cgcccgcacc cgcgcggcca cgtcgttcat ggtgagccgg ccgccggagt
    21721 cggtgacgta gacgcagtgc gcgccgtagg actccatcag cttcgcctgg cgggccagct
    21781 cctccggcgg ggccatgtgg gagagcatca ggaagccgga cacgtccatg ccgagctcgc
    21841 gcgccgcggc gatgtgctgc gcggagatgt cggcctcggt gcagtgcgtg gcgacccgga
    21901 cggagcgtac gccgaggtcg tgggcgcgct tcagctcgtg gacggtgccg actcccggca
    21961 gcagcagcgt ggtgaggcgg gcgttcacca gcaccgacgc cgccgcttcg atccactccc
    22021 agtccgtgtg cgacccgggg ccgtaggtga gcgaccctcc ggcgaggccg tcgccgtgcg
    22081 cgacctcgat cgcgtcgaca ccggcccggt cgagcgcggc gacgatgcgc ttgacgtcct
    22141 ccgtggagat ccggtggcgc acggcgtgca tcccgtcgcg cagcgtgacg tcctggacga
    22201 agatcggggt gcccatcaca ggcccgcctt ccgtgccgcg atgcgctccg cgacccgcag
    22261 gccggcggag gtcatgatgt cgaggttgcc ggcgtaggcc gggaggtagt gcgcggcgcc
    22321 ctcgacctcg aggaagaccg acacctggtg ggtgggccgg gaggcgccgc cggcgaggag
    22381 cgtcccgacc ggctggccgg cgggcacctc ggtgatctgc acctgctgtt tgagccggta
    22441 gccggggacg taggccgcga cgtcggcgac catcttctcg accgaccgcc ggatctcctc
    22501 gcgtgcggcc gggtccggcg cggtgacgag gcacaagacg gtgtcccgca tgatcatcgg
    22561 cg
//
