LOCUS       NZ_BBZG01000001        22577 bp    DNA     linear   CON 12-AUG-2024
DEFINITION  Nonomuraea pusilla strain NBRC 110462, whole genome shotgun
            sequence.
ACCESSION   NZ_BBZG01000001
VERSION     NZ_BBZG01000001.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Nonomuraea pusilla
  ORGANISM  Nonomuraea pusilla
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Streptosporangiaceae; Nonomuraea.
REFERENCE   1
  AUTHORS   Komaki,H., Ichikawa,N., Hosoyama,A., Fujita,N. and Igarashi,Y.
  TITLE     Draft Genome Sequence of Nonomuraea sp. TP-A0861, a Producer of
            Myxochelin A
  JOURNAL   Genome Announc 3 (6), e01430-15 (2015)
   PUBMED   26659677
  REMARK    DOI:10.1128/genomeA.01430-15 Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3746196)
  AUTHORS   Hosoyama,A., Kimura,A., Ichikawa,N. and Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-AUG-2015) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, Biological
            Resource Center (NBRC); 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.nite.go.jp/nbrc/index.html
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Noncontiguous Finished
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.8
            Genome Coverage                   :: 107x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001417755.1-RS_2024_08_12
            Annotation Date                   :: 08/12/2024 01:46:03
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,307
            CDSs (total)                      :: 8,242
            Genes (coding)                    :: 8,159
            CDSs (with protein)               :: 8,159
            Genes (RNA)                       :: 65
            rRNAs                             :: 1, 1 (5S, 16S)
            complete rRNAs                    :: 1, 1 (5S, 16S)
            tRNAs                             :: 60
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 21 of 83
            Pseudo Genes (incomplete)         :: 72 of 83
            Pseudo Genes (internal stop)      :: 5 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            CRISPR Arrays                     :: 3
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:25:31
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1123487
            Orig. end                         :: 1146064
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBZG01000001.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22577
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="7"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22577
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22577
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12577](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12577
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            complement(981..1928)
                     /locus_tag="ASC57_RS04970"
     CDS             complement(981..1928)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018656279.1"
                     /locus_tag="ASC57_RS04970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="YafY family protein"
                     /protein_id="WP_055501736.1"
                     /transl_table=11
                     /translation="MSYPATRMLTMLELLQAHHGLSGRDLAQRLGVDERTIRRYAARLA
                     ELGIPVTAERGRYGGYQLMPGYKLPPLMLTDDEATAVVLGLLAGRRLGLAADATEAALA
                     KIRRVLPTTLREQVGALEETLDFTLADRAAPTPAGRAVLTLAAAIRDRRRVTLRYRSWK
                     GAQTERELDGHGLVLHSGRWYVTGHDHLSGEIRTFRLDRISSVVPGTASYEIPGNSDPV
                     RQVTASLAQVPYAHIVEVILHVPLAEASRRIPPSVATLTETTDGVLLQTRAESLDGMAA
                     MLAGLGFRFTILSPQELRPAVRRLAERLLEQTTE"
     misc_feature    complement(1957..1972)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.74"
                     /tool="antismash"
     gene            2011..2718
                     /locus_tag="ASC57_RS04975"
     CDS             2011..2718
                     /NRPS_PKS="Domain: Abhydrolase_1 (4-104). E-value: 1e-08.
                     Score: 27.0. Matches aSDomain:
                     nrpspksdomains_ASC57_RS04975_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018656278.1"
                     /locus_tag="ASC57_RS04975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_055501737.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.2e-10, bitscore:
                     40.0, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANYVLVPGFWLGGWAWDEVAQQLRAAGHQVRAVTLTGLAERAGE
                     LSAEVGVETHVGDIVAAMDGWEEVVLVGHSGASVPVTAVADRYPERLSRVVYVDTAPLP
                     SGVAVIDFNDEETQKAWRAQVGDGCALDVPSFKEGDGQFAGLTEERWAQIRERATPHPW
                     GAVTQSVQRPQRIPATPKTMVASTMPVALIRELIASGNPAFAPLGTPEWTFVELPTGHW
                     PMFSRPADLAALL"
     aSDomain        2023..2322
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ASC57_RS04975_Abhydrolase_1.1"
                     /evalue="1.00E-08"
                     /label="ASC57_RS04975_Abhydrolase_1.1"
                     /locus_tag="ASC57_RS04975"
                     /protein_end="104"
                     /protein_start="4"
                     /score="27.0"
                     /tool="antismash"
                     /translation="VLVPGFWLGGWAWDEVAQQLRAAGHQVRAVTLTGLAERAGELSAE
                     VGVETHVGDIVAAMDGWEEVVLVGHSGASVPVTAVADRYPERLSRVVYVDTAPLP"
     gene            complement(4380..4739)
                     /locus_tag="ASC57_RS04985"
     CDS             complement(4380..4739)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC57_RS04985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_055501739.1"
                     /transl_table=11
                     /translation="MSTLAERLRAGVRHGSRAEIAAVELLIADTESGWFYHDEGDFVYY
                     CVSDDRDNDTASIDWDEARRFFENADPDYEIANKIAILDFAIALIEDRFRLGFLSDQQR
                     RLFATAAANATGNGG"
     misc_feature    4854..4869
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.22"
                     /tool="antismash"
     gene            5285..5437
                     /locus_tag="ASC57_RS43620"
     CDS             5285..5437
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC57_RS43620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_176573282.1"
                     /transl_table=11
                     /translation="MRVNVSSEMDVRRGGRFVSDLAASACLGCGRVFLYVVHLDRVREV
                     FGSGP"
     gene            5469..5666
                     /locus_tag="ASC57_RS04990"
     CDS             5469..5666
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC57_RS04990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_201784431.1"
                     /transl_table=11
                     /translation="MTLRGARFFGADLRGVRLQADDLGWSFGSGTVLAGAAQDLLLVAY
                     GRRLPRGRLRGEAVARFTAG"
     gene            complement(5782..6369)
                     /locus_tag="ASC57_RS04995"
     CDS             complement(5782..6369)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016407 - acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Mac"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156: Chloramphenicol acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017592059.1"
                     /locus_tag="ASC57_RS04995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sugar O-acetyltransferase"
                     /protein_id="WP_055501740.1"
                     /sec_met_domain="Mac (E-value: 1.3e-05, bitscore: 22.9,
                     seeds: 568, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTDLFAGDPRTNRERMLAGDLYIADDPESARIAQQATALLETY
                     RLQTVAGEHEQARQTLTRALGTLGPDAYVKPPLFVDYGENIHIGARTFINHNLTALDVA
                     TITIGEDCQIGPGVQLLTPTHPVEPGPRRDKLEAAEPITIGDNVWLGGGVIVCPGVSIG
                     DNSVIGAGAVVTRDIPPNVVAAGNPARVLRTI"
     gene            complement(6400..7275)
                     /locus_tag="ASC57_RS05000"
     CDS             complement(6400..7275)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0030416 - methylamine metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018942.4"
                     /locus_tag="ASC57_RS05000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MauE/DoxX family redox-associated membrane
                     protein"
                     /protein_id="WP_055501741.1"
                     /transl_table=11
                     /translation="MNALVTGVLGSAHLALIAVLLPAAATKARDLRRFASDIAGYRLLP
                     TRLTTPAALLLIAAELAASALLTLPATRRTGALLAGLLFAAFLTAMATVSYRGLRTACG
                     CFGGSDAVGPRTLLRTGLLLALAAAATAGGAAPFTAAQLLYAPLLLAAALLPPLLVRPA
                     PPPPPGPRPGDRFTVADPAQPRPRPTLYALVSPGCGLCSAMLPAFAAASARLDVVLVSA
                     AHPDDVRAYLDDHDIHLPHLTDPHVFDANAIPWPPYAVLAGPGATVLAAGGTSSPEQLA
                     LLLDQAPTPH"
     gene            complement(7453..9441)
                     /locus_tag="ASC57_RS05005"
     CDS             complement(7453..9441)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017592961.1"
                     /locus_tag="ASC57_RS05005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_082534665.1"
                     /transl_table=11
                     /translation="MKLWGTWRHTATSTEPHQKPDDEPDDRRDTAPDDRSGLETAYWET
                     HDEELLNAGLAAIARRLPFLVASALRLAWQAGRRDTVVALAGNVLAGAFTVYGFVATSD
                     VLTSLFAGGPTPGRVRDALPSLALLAAAATLRGALLTAATWAQARLKPQVERLAETRLL
                     DLTTRVDLAAFDDDDFHNAMRRARDSGVPDTATVVETTIAALTATVGVASATAALGLLH
                     PLLMPLLLLTALPAGWAAVRAGKLGYQAFYRLSAARRRKFMLSDLMAERQPAAEVRAFD
                     LRDFLLAEYAKVAALEQRVQLDVARRRTTVKAGGDLLTGAATLGVYAALATLLAAGVIP
                     LAVAGTAVLAIRTGQTSLAGLVQTLNRLYEAGLYFGDYLTFHALATTRTTPPAQAPTGT
                     DVTPAAPARLARLTADHVTFTYPGADRPALREAAVTVARGEVIALVGENGSGKTTLAKL
                     LAGLYHPQSGAIRWNGADITRLDLRGLISVIAQDHTRWPLTVRENILMGRPLDQARLAE
                     AATAAGADEVVATLTHGYDSLLDRRFRGGHDLSGGQWQRIAVARGFYRDAELVIFDEPT
                     SALDARAEHALFERIRKHADGRAIVLITHRLASVRYADRIYVLDHGRVTEQGTHTELMA
                     LGGLYAELYGLQAAAYRLDDHADHPHG"
     misc_feature    complement(9460..9475)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.65"
                     /tool="antismash"
     misc_feature    complement(9635..9655)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.74"
                     /tool="antismash"
     gene            9712..9882
                     /locus_tag="ASC57_RS43625"
     CDS             9712..9882
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC57_RS43625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_176573283.1"
                     /transl_table=11
                     /translation="MSVLALEPRDAGVLEFEDFDVDFDGELAKLLHGPQACANTCKRTV
                     CSSFPCCPSIV"
     CDS_motif       9712..9798
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MSVLALEPRDAGVLEFEDFDVDFDGELAK"
                     /locus_tag="ASC57_RS43625_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9799..9882
                     /prepeptide="core"
                     /locus_tag="ASC57_RS43625_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="-2.60"
                     /molecular_weight="2746.3"
                     /monoisotopic_mass="2744.3"
                     /core_sequence="LLHGPQACANTCKRTVCSSFPCCPSIV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MSVLALEPRDAGVLEFEDFDVDFDGELAK"
                     /leader_location="[9711:9798](+)"
     misc_feature    9959..9974
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.44"
                     /tool="antismash"
     gene            10001..12577
                     /gene="lanL"
                     /locus_tag="ASC57_RS05010"
     CDS             10001..12577
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="ASC57_RS05010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_055501742.1"
                     /sec_met_domain="Pkinase (E-value: 8.6e-16, bitscore: 55.7,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.9e-16, bitscore:
                     56.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAASVAVDVLEILTGFAAEHGRDVYEDDTWVSVHSPSGGIPAQGW
                     KLHVSARPGTLGETIERALPVLLEHGCDFKVARSAETLRELNSGDVDAGAVGKAITAYP
                     AQDRVVALGHALADALAGMAGPRIVSDRRVRQDAPVYYRYAPFAPQYRVDDNGDFELVV
                     VGPDGERLPGAAGPEFSCPPWASDPFRPPAAGAARQAREPASETAPARLIGNRYRVTSG
                     VVRGPRGNVYRAADPSGRPVVVKEARAYVGENPQGWDLRMYLRNELRVLKALRGVEGVP
                     RPLDHFRHGDDEFLVMTDAGSLDLNRFVGERGLFTDGGGERDLAALAGRLLAVLDAVHG
                     RGVVVRDLSPKNVVIGEDGRCTLIDFGNSRYEGLQLPGWTRGYSVPDQRSGRDSEPSDD
                     YFSLGATLFFACAGMNPVMIDADPVRNLERTLMCLERLFPGVRTGVRGLLPRLMSLEAA
                     ERGRAADDLRAGRLDGRDRTVIAVPRWSGELLSRVMEHTTRACVAFAEGLMEAPEGARR
                     SSPPVTNVYGGSAGLGMELLHHRRARAVGVDLARWTARVMPPVVLPPGLYFGRTGTALF
                     LAAARSSGAPELERALPVELGGDQRADQAHGVAGIGAGHLALAALERDPRHVEVAAECG
                     RLLMAGEVSQSRDAVAPAQPGTGVAVESAFAHGAAGCADFLLSLWEATGDERVGRAAAG
                     RFAELAEVAGVLLEELAGPAARPMGASWCQGMSGVAGALAHAGRALGEDRYVELAERGA
                     RACLALAPQAWVVSQCCGLAGIGECLIDLALLTGDEFYWRGAEEVAVLMLVRGGGEPDA
                     PVFPGNDLDKAGFTWATGASGVLSFLRRLDQRSGERLWTASWRLPG"
     misc_feature    complement(10022..10036)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.88"
                     /tool="antismash"
     misc_feature    complement(10027..10045)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            complement(12694..12834)
                     /locus_tag="ASC57_RS41135"
     CDS             complement(12694..12834)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="ASC57_RS41135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_201784433.1"
                     /transl_table=11
                     /translation="MSPCRLLRRLQGPLQYRNVHPDYVERLWDLVDRADVAARHTAATS
                     T"
     gene            complement(12910..13620)
                     /locus_tag="ASC57_RS05015"
     CDS             complement(12910..13620)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132405.1"
                     /locus_tag="ASC57_RS05015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_055501743.1"
                     /transl_table=11
                     /translation="MQAVDGTSTLTDQVFESVRKAIHSGELRPGQLYSVYQLAAELKVS
                     RTPVREAMLRLAEAGLVRFERSRGFRVLRSDPKEIAEVFHLRLLLEVPAARLAAHRRDP
                     ALLQAMRAELEEMREAAAAHDEPRFMRHDAAFHRLLLQGGHNGKLVGIVDNLRDATITL
                     GASTVDRSRSLPDIAREHEPILAALEAGDAEAVAAAMRTHIGHTGELLLAQAAAANGVP
                     VDPDDLALIRATSA"
     misc_feature    complement(13684..13702)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.76"
                     /tool="antismash"
     gene            13738..14538
                     /locus_tag="ASC57_RS05020"
     CDS             13738..14538
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132406.1"
                     /locus_tag="ASC57_RS05020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="N-acyl homoserine lactonase family protein"
                     /protein_id="WP_201784434.1"
                     /transl_table=11
                     /translation="MKLHVLDCGAMSCDLTWLLLKPGRTIRPRAERDRPVEWYPCTTHA
                     VLVETDEGSLLWDTSCPRDWETRWIPTGLQEFFPYDQVSDEQYLDAQLGRLGVSPDRLD
                     YVVLSHLHFDHAGNVRMFAGTGARLVCNDKEKEFAFGYEGAFDGAHLKADYEGLDFQTV
                     SGDTEILPGVTLIEAPGHTVGTMAMKVDLPETGTMIFTSDAVYMGDSYGPPATPAAIVN
                     DLTAWYASVEKIRSIAERSDATVIFGHDAEQLRSLRTAPDGFYQ"
     gene            14553..15839
                     /locus_tag="ASC57_RS05025"
     CDS             14553..15839
                     /EC_number="1.1.99.24"
                     /GO_function="GO:0004022 - alcohol dehydrogenase (NAD+)
                     activity [Evidence IEA]"
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0047988 - hydroxyacid-oxoacid
                     transhydrogenase activity [Evidence IEA]"
                     /GO_process="GO:0006629 - lipid metabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012851106.1"
                     /locus_tag="ASC57_RS05025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxyacid-oxoacid transhydrogenase"
                     /protein_id="WP_055501745.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.4e-107, bitscore:
                     357.3, seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFTAPSNPESVFTYGAPALKFGTGASAEIGFDLGQYGVRRVLVVT
                     DARVAATGSPARIAEQIAGYGIEAHVYDGVHVEPTDASLQAAIEHARASGPWDAFVAVG
                     GGSAIDTAKAVNLLTTNPGTLMDYINVPVGGGRAPSEPLKPLVAVPTTTGTGSESTTIC
                     VLDVLELKVKTGISHARLRPVLAVVDPELTMTQPAGVTAAAGMDILCHALESYTARPYT
                     SYERKKPQERVPYCGANPVADMWAEQALRLLAQSLRAAVRDGGDAEARGRMAMAATFAG
                     LGFGNAGVHIPHANAYPIAGRVRDFHPDGYPKDEPMVPHGMAVALSAPEAFRFTFEADP
                     GRHLRAAELLAPDAERPSDLAGHLPSVLRALMRDIGIPNGIGGVGYGEQDVPALVEGAM
                     KQQRLLATAPRPVGEEDVAAILTRSIALW"
     gene            15850..16362
                     /locus_tag="ASC57_RS05030"
     CDS             15850..16362
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132408.1"
                     /locus_tag="ASC57_RS05030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FmdB family zinc ribbon protein"
                     /protein_id="WP_055503815.1"
                     /transl_table=11
                     /translation="MAIYELRCVRGHRFEVIQSFTAPLPACRECGAETGKVPSTFGFGG
                     RASGALPPPPELMPQTWRGTYGADREYVTGLRRAAESRRALEERNPELAGDRRPVLAHE
                     GRFEAAPLRAGDPLPLGGGHTYGHTHGHTHGHGHGHTHGHGHGHTHGQGHGGVAGAPAA
                     GREGDSS"
     gene            16467..19241
                     /locus_tag="ASC57_RS05035"
     CDS             16467..19241
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018655590.1"
                     /locus_tag="ASC57_RS05035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding and (Fe-S)-binding domain-containing
                     protein"
                     /protein_id="WP_236714582.1"
                     /transl_table=11
                     /translation="MPPLAVAFPRHADEVAAALAWCAAEGVPLTARGGGTSIAGNAVGP
                     GLVLDFSRHMGRITAFDPQEGTATVEPGVVLDDLQRRAAPYGLRFGPDPSTHSRCTLGG
                     MIGNNACGSRALAYGRTADNLLALDVLTGGGERLSTDAAGSSPALRALREVVGRNLAVI
                     RTEMGRFSRQISGYSLEHLLPENGFDVARAFAGSEGTWGVLLGAKVRLVRAPAHTVLAV
                     LGYPDMAAAADAVPALLPHRPVALEGIDARIVEAVRRRRGDHAVPPLPGGRGWLLAELG
                     GSSPAEAGAAARALVAGSGALDSLLVADAAQAAAAWRIREDGAGLSARTPAGAPAHAGW
                     EDAAVPPEGLGAYLRVFEELMAGYGLTGLPYGHFGDGCVHVRIDFPFGRADGAAVFRSF
                     LTDAARLVAEHGGSMSGEHGDGRARGELLPLMYSPAALEAFAQVKAVFDPGEVLNPGVI
                     VRPAPLDEALRLQPPPPRASGLALRYPHDGGDLSAAVHRCTGVGKCRSHAAGPGAVMCP
                     SYQATRDEKDSTRGRARVLQEAVAGRLPGGLRAPEVREVLDLCLSCKGCLSDCPTGVDM
                     ATYKAEVLHQSYRGRLRPAVHYSLGWLPRWARLASLAPAAVNAVLRVGPVAALAKRAGG
                     IDARRPLPAFAGRRFRRLRPARAGRPGGTAGAGGRRVLLWVDTFTDHFAPQVAEAAVRV
                     LTRAGCEVAVQRDSQCCGLTLISTGQLDAAGRLLRRTVAALAGHARAGTPIVALEPSCT
                     AVLRSDAADLLGSDSAGEGAGEGAGAGGDDVAVVAGAVRTLAEFLGELPGWRPPDLSGV
                     RVLAQPHCHHHAVMGWEADRALLARAGAQVSAVGGCCGLAGNFGMERGHYEVSVAVAET
                     QLLPAVRRAAPGTVLLADGFSCRTQLDQLAHVRAFHLAELLAGRAQAVPGSGG"
     gene            complement(19214..20089)
                     /locus_tag="ASC57_RS46290"
     CDS             complement(19214..20089)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024698.4"
                     /locus_tag="ASC57_RS46290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_082534666.1"
                     /transl_table=11
                     /translation="MLEPRYPISTERLTLRPFTPDDLDAVHAYESLPEVARYLYWEPRD
                     RDTARGFLDKKIARTALREEGDAIDLAITLTATGEVIGNTLLAWTSRRHRQGEIGYVLH
                     PAHHRRGYAAEATREMLRLGFEQLGLHRIVGRLDARNTASASVLRKLGMRQEAHLVENE
                     VVKGEWTSEIVYAVLAREWPAAPAPASVLHLALRSDWEAARPAGEYRVSTLGRTLEQEG
                     FIHCSRDAAQLRTVHDTFYTAVTEPLVVLHIDTTGLDVRVEGGFPHLYGPLPAGAVTAV
                     HPYPPEPGTA"
     gene            complement(20112..20696)
                     /locus_tag="ASC57_RS05045"
     CDS             complement(20112..20696)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF037009.4"
                     /locus_tag="ASC57_RS05045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_055501747.1"
                     /transl_table=11
                     /translation="MNPQQEPAPAPSAGPPPVQERGRRRRAHLLAAAVGLLAEGGFAAV
                     THRNVARRARLPLAATTYYFASRDQLLAEAFAQLVEAELATTRDWVARHGLRALPEQVA
                     AADRARQLGLWELYVHAGRDPALQRIARRWTDGCVRLVADALTLPETDPRARLVYTTLS
                     ALWLEHVVEQRPLADARALLDAAVENALRPA"
     gene            complement(20693..21016)
                     /locus_tag="ASC57_RS05050"
     CDS             complement(20693..21016)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891087.1"
                     /locus_tag="ASC57_RS05050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_055501748.1"
                     /transl_table=11
                     /translation="MAWILLAFAIASEVLATSALKLSNGLTHLGWSVVVAAGYLVSFVL
                     LARALKLQLEMGTAYAVWSGAGTAAIALIGAAFMGESLNPAKIGGILLIIGGVVVLNLA
                     GGH"
     misc_feature    21100..21115
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.77"
                     /tool="antismash"
     misc_feature    complement(21101..21115)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.19"
                     /tool="antismash"
     misc_feature    21102..21113
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 17.72"
                     /tool="antismash"
     gene            21125..22078
                     /locus_tag="ASC57_RS05055"
     CDS             21125..22078
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546918.1"
                     /locus_tag="ASC57_RS05055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="radical SAM protein"
                     /protein_id="WP_082534667.1"
                     /transl_table=11
                     /translation="MGWDALPLVDAVDERPPIERRAVVRDGFYETQARAVIERVPETAG
                     IAQSWALSPYRGCAHACRGCGARAGHRRLGLDAGRDFDTRVVVKANAVSRLRAELARWG
                     GEPLAVGVSGDCYQPAERVYTLMPGLIAALGEAAVPFTVYTRSPLVLRDAELLAEAGAQ
                     VAVSIAFVDERIRRAVEPGAGGAQSRLELVSALVEAGVDCRVLMAPVLPLLSDAADQLA
                     ATVRRIAGAGARGVEPVVLRLPPGTREWYLGWLAEAHPHLVARYEELYDRAGLPSPGYE
                     QRITGQIAQLCQVYGLPCGAPPPPVRRPRFPQLSLV"
     misc_feature    22141..22155
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
ORIGIN
        1 ccgccaggcg gtaggcaaga agagcgctgg gcggtgggca agagcgctgg gcggctcgtc
       61 gaagcggggc cggagccaca tctgaggccc cgctagccga ggtcctccgg cagcgtcttg
      121 ggctgctcgt ccaagagtag gccccgccgc gtggcgcgtg ccgctggaaa ggccgtcctc
      181 cccctccagg aagcaggaag gccgctctcc cctcccccgc ttcgcctctt cccgcccacg
      241 cccgcccttc cccttcccgc ccttcccctt cccgcctcct cccctgcctg gccggcctcg
      301 ctctgcctgg ccggcctcgc tctgcctggc cggcctcgct ctgcctggcc tggcccggcg
      361 ccgggctcca gcgccccgcg cggcgctgga gcccggccct cgccctgcgt ggccctgcgt
      421 ggccctgcct gggtctgcct gggtctgcct gggtctgtct agcgatgcct ggccatgcct
      481 gcgtctgcct ggtccctgcc tgggtgtgac acggcctggc ccggcccgcc tgcggcccag
      541 ccgggccgta gctcggccgc tctggttcgt cgtgcggcgg tccgctctgc ggcggctcgt
      601 cccggcgtcg gctgttgtgt gtggtggcga gggctgcagt gctcgtgagg cggtgaccgg
      661 tggagaggct gaggtgggtc tcccccggtc cggctggccg gtctgcccgg ggccgaagtg
      721 gggtcggtgg ggtggtggag gaccatcagc cggtgctcgg tggggtcgta cggcgtcctc
      781 ctcgtcgacc ttctgctgat cttctgcggg tgctgtcgga atggggcagg agccggccac
      841 gacctgaggt ggtcgctggt cagcaacggc tgcggcgatg tccgcggcgg tcgcggagtt
      901 acgtgtggtg cgtttctgcg ctgaggctga tcatcaccgt cagctgcgcg gtggtctccg
      961 gcggccgggc gttgggagtg tcattccgtc gtctgttcca gcaggcgttc ggccaggcgc
     1021 cggacggcgg ggcgcagttc ctgtggcgac aagatcgtga atcggaagcc gagcccggcg
     1081 agcatggcgg ccatgccgtc cagggactcg gcacgggtct gcaggaggac tccgtccgtt
     1141 gtctcggtga gggtggccac cgatggcggg atgcggcggg acgcctcggc gaggggaacg
     1201 tgcaggatga cttcgacgat gtgcgcgtac ggtacttggg ccagcgacgc ggtgacctgc
     1261 cgcaccgggt cggagttgcc ggggatctcg taggaggccg tccctgggac gacggaggag
     1321 atccggtcga ggcggaaggt gcggatctcg ccggacaggt ggtcgtggcc ggtcacgtac
     1381 cagcggccgg agtggaggac caggccgtgg ccgtccagtt cgcgttcggt ctgggcgcct
     1441 ttccaggagc ggtagcgcag ggtgactcgg cggcggtcgc ggatcgcggc ggccagggtc
     1501 agcacggcgc ggccggcggg ggtcggcgcc gcgcggtcgg cgagggtgaa gtccagggtc
     1561 tcctccagtg cgccgacctg ttctcgtagc gtggtgggca gcactcggcg gatcttggcg
     1621 agggcggctt cggtggcgtc ggcggcgagg cccaggcggc gtccggcgag cagtccgagg
     1681 accacggcgg tggcctcgtc gtcggtgagc atcagcggtg gcagtttgta gccgggcatc
     1741 agttggtagc cgccgtagcg gccgcgttcg gcggtgaccg ggatgccgag ttcggcgagt
     1801 cgggcggcgt agcgccggat ggtccgttcg tccacgccga ggcgctgtgc caggtcgcgg
     1861 ccgctcagcc cgtggtgggc ttggagcagt tcgagcatcg tcagcatccg ggttgccgga
     1921 tatgacacag gtcacccact taatccgggc gggttctgtc cgctatcggc tctagcgtag
     1981 cgacatcgga atcactggaa ggacgatgag atggcgaact acgtgctggt tcccggcttc
     2041 tggctcggcg gctgggcttg ggacgaggtg gcgcagcagc tgcgtgccgc gggacatcag
     2101 gtgcgggcgg tcacgttgac ggggctggcg gagagggctg gggagttgtc ggcggaggtc
     2161 ggcgtggaga cgcatgtcgg tgacatcgtc gcggcgatgg acggatggga ggaggttgtc
     2221 ctggtcgggc acagtggggc gagtgtgccg gtgaccgcgg tcgccgaccg gtatcccgag
     2281 cggctcagcc gggtcgtcta cgtcgacacc gcgccgctgc cgtctggtgt ggcggtgatc
     2341 gacttcaatg acgaggagac gcagaaggcc tggcgcgctc aggtcgggga cggttgcgcg
     2401 ctcgacgtgc cctctttcaa ggagggggac gggcagttcg cggggttgac cgaggagcgt
     2461 tgggcgcaga tccgggagag ggcgacgccg cacccgtggg gtgcggtcac ccagtcggtt
     2521 cagcggccgc agcggatccc ggcgacgccg aagacgatgg tggcctcgac gatgccggtg
     2581 gcgttgatcc gtgagctgat cgcttcgggg aacccggcgt tcgccccgct cggcacgccg
     2641 gagtggacct tcgtcgagct gccgaccggt cactggccga tgttctcgcg gccggcggat
     2701 ctcgccgcgt tgctctgacg acctccgctt ggtgtccggg cctgattcgt gcttgttccc
     2761 agggggcctg tgatcgccgc cggtcctcct gacgcggtgc tggaagacgc ctccgacatg
     2821 gggcggtgtg acgatccgtc gggatgctgg ggtgccggcg gtgtgcgagc tggggctcag
     2881 gtccgggctg agcactcctc gtcctggccg agatcggggt ggcgcctgct ggagcgggcc
     2941 ggggttcgcc gaatgtccgg gggtgtcacg acggtcatcg gtgcggccct gcggtggatg
     3001 cccggccccg ctcggttcgt ggacgggctt gagttcgccg ccgccggggc ggttctccta
     3061 ggggtaccag taagaaacgt gtcatgagcc ccaaacggcg ttgatcttgt tccggggcag
     3121 tccggaaccc tgctcagtag tccgtgatga gggcgtccag ggcggcggcc tttcggcctc
     3181 ggtgggcaag gcgtaggccg ctttgaggcg tcctcggcgt tgagcgtccg gtccttccat
     3241 ggcccgatgg catcggccgg gtcgggtccc ggcttggcga gtgacagcgt ggccatggcg
     3301 ctcgctttcg ctttggagct gcgccctcgt catgctcgcg cgccacgtcc ccgacgtcgc
     3361 aaccacctca tccagcaagc cgaacccctg ctacgtcaac gcgccctcga cgtctccgac
     3421 gctcaccgcc gatcagcgct gcgccacagc gcgctgctcg gcctcgccca catcgcagca
     3481 ggcgacctcg atcaggccgt gcacgccggg cgcctcgcgg tgcgacggct tccgatggtg
     3541 acttcaatcc gctgccagcc cctgctggga gagctccgct ccgagccggc cgcccatgcc
     3601 cagaggtccc aggatgtgcg aagcctcatc gcagagatcg acacccacgt gctgggtctg
     3661 tctcggcgct gacggcggat gggagagaac agccccggtg cgttcgtcct cctgagactt
     3721 ggaccaagcc gtggcggcgg ctactcatgc catccgctgc ctggtgggag tggactccgc
     3781 caggtcgacg gcgacccgag gaactgaggg gcaagctggc ggagtaccgg catgtgcctg
     3841 tgatcggaca ttgtggcgcc gcaacgccat cgcgggcatc accgcgcccc ggcgactcgg
     3901 ggctcggcac cggccacagg tcgcggacca cgtccttggc gaaggggccg agcagcggat
     3961 cctggtcggc gagcactggg cctggccgac gacgtgcctg gccaacaggg cctgccggta
     4021 agaatcgcac cacacggccc aaacgagcgg cgtcgccgca ggtcacggcg cgcgacggtg
     4081 tcacccgcag agggccggtt tcggtccggg cgttcgggga tgagtcaggc gccctgcggc
     4141 gcgataaagc tggatcgagc gttttcagta gttacggggg tcgaggccgg caacatcgct
     4201 ccctgaccgg acagagcgca cggtcggtcc ggtcacctgg atcccattgc cgcagtttga
     4261 tgccgtgaca aggatgcggc cgctaatccg gtccgaccag cacgtggctg ctccgtcgcc
     4321 gcaaccccgt cactccgccc gggatcgagt cgcaggtcaa cgccctgtca cgtgttcctc
     4381 taccctccgt tcccggtggc attggctgct gcggtcgcga ataggcggcg ctgttggtcg
     4441 ctcagaaagc cgaggcggaa gcggtcttcg atgagcgcga tggcgaagtc gaggatggcg
     4501 atcttgttcg cgatctcgta gtcagggtcc gcgttttcga aaaatctgcg ggcttcgtcc
     4561 cagtcgatac ttgctgtgtc gttgtcacgg tcgtccgaca cgcagtaata gacgaaatcg
     4621 ccctcgtcgt gatagaacca cccgctctcg gtgtcggcga taaggagttc gacggcggcg
     4681 atctcggctc ggctgccgtg gcgtaccccg gcgcggagtc gttcagcgag agtgctcatg
     4741 cgaagattgt ttcaccccgc tcgggggccg gggttgacgt tcccgccgaa tcgccgcaat
     4801 tgccctgtat gaccttgagc gaaccaagat ccatatcagc gccaacggcg gccctcaggt
     4861 cttctcgacc ccggttatac gcaccgtcgc tttgggccgt gtggtgcgat tcttaccggc
     4921 aggcctccta cgggtgttcg gatgcgacag aaccgcgtca tagcgggcat ggggccgtca
     4981 tgacaacaag gggcggtgtg gggcggtggt caggcggggc cgaggacggc gggggtggcc
     5041 agggcgcggg cggtgtcggc ggcgtactgt tcgtcggcgg tgtcggtgag gccgaggacg
     5101 acggcttggc tgagtccggt gagcaggccg cgtagggcga tggcgagggg gcgccgtggt
     5161 ggcggcgtcc ggtgaacagg tcggtgaggc gttcctcgtg ggagcggacg gcggcggcga
     5221 agcgaatcgg cgcaggtcgg ggtcgcggag ggcggcgtcc tgtccggact gtgaggggcg
     5281 gcgggtgcgg gtgaacgtgt cgagcgagat ggatgtgcgc cggggtggtc gcttcgtcag
     5341 cgatctggcg gcgtcggcgt gcctggggtg tgggcgggtc ttcctgtatg tggtgcatct
     5401 ggacagggtg cgggaggtgt tcggttcggg gccgtgaccc tgatcggcgg ttctcgcaac
     5461 tggaggcggt gacgctgcgg ggggcgcggt tcttcggcgc cgatctgcgt ggggtgcggc
     5521 tgcaggctga cgatctcggc tggtccttcg gctcggggac ggtgctggcg ggggcggcgc
     5581 aggatctgct gctggtggcg tacgggcgca ggttgccgcg ggggcggctg cgtggggagg
     5641 cggtggcacg cttcacggcg gggtgaggag gcgggccgcc gtgtcgttcg cggtgttccc
     5701 ccggggcgcc cgctcccccg ccgcgaccgt ggaggggggc gtctcccccg gtgtcatcgc
     5761 cccggcggcg gggacggggt gtcagatggt gcgcaggacg cgggcggggt tgccggcggc
     5821 gaccacgttc ggcgggatgt cgcgggtgac gacggcgccg gcgccgatga cgctgttgtc
     5881 gccgatgctg acgccggggc agacgatgac gccgccgccg agccagacgt tgtcgccgat
     5941 ggtgatgggt tcggccgctt ccagcttgtc gcggcgcggt ccgggctcga cggggtgggt
     6001 gggggtcagc agctggacgc cggggccgat ctggcagtcc tcgccgatgg tgatcgtcgc
     6061 gacgtcgagg gcggtgaggt tgtggttgat gaaggtgcgg gcgccgatgt ggatgttctc
     6121 gccgtagtcc acgaacagcg ggggtttgac gtaggcgtcg gggccgaggg tgccgagcgc
     6181 gcgggtgagg gtctggcggg cctgttcgtg ctcgccggcg acggtctgca gccggtacgt
     6241 ctccaggagc gccgtcgcct gctgcgcgat gcgggcgctt tcggggtcgt cggcgatgta
     6301 gaggtcgccg gcgagcatgc gttcgcggtt ggtgcgtggg tcgccggcga agaggtcggt
     6361 ggagctcatg tgttcgaccg tacgaggtgt ggccgggtgt cagtgcgggg tgggggcctg
     6421 gtcgaggagg agcgccagtt gctcggggct ggaggttccg cctgctgcca ggacggtggc
     6481 gccggggccg gccaggacgg cgtagggcgg ccaggggatg gcgttggcgt cgaacacgtg
     6541 ggggtcggtg aggtgcggca ggtggatgtc gtggtcgtcg aggtaggcgc gtacgtcgtc
     6601 cgggtgggcg gcgctgacca ggacgacgtc caggcgggcg gaggcggcgg cgaaggcggg
     6661 cagcatggcc gagcacaggc cgcagcccgg ggagacgagg gcgtacaggg tggggcgcgg
     6721 acggggctgg gcggggtcgg cgacggtgaa gcggtcgccg gggcggggcc ctggaggcgg
     6781 gggcggcgcg gggcggacga gcaggggcgg caggagggcg gcggccagca ggagcggcgc
     6841 gtacaggagt tgggcggcgg tgaacggggc cgctcccccg gcggtggcgg cggccgcgag
     6901 ggcgagcagc aggccggtgc gcaggagtgt gcgggggccg acggcgtctg agccgccgaa
     6961 gcagccgcag gcggtgcgca ggccgcggta cgagacggtg gccatggcgg tgaggaacgc
     7021 ggcgaacagc aggccggcca gcagcgcgcc ggtcctgcgg gtggcgggga gggtcaggag
     7081 cgcggacgcg gcgagttcgg cggcgatcag cagcagggcg gcgggagtgg tcaggcgggt
     7141 gggcagcagg cggtagccgg cgatgtcgga ggcgaatcgg cgcaggtcgc gggccttggt
     7201 ggcggcggcg ggcagcagca cggcgatgag agcgaggtgg gcggagccga ggacgccggt
     7261 gacgagggcg ttcacgcgac cgccgcctgg gcgcggccgg ggagacgggg ggcgtcggtg
     7321 gcgggccggg tcacgcggtc gcgttctggc gggcggcatc gcccgggaag ctgtgcggtg
     7381 gcgggccggg ggcagggtgg gacgtcggcg gcggtggccc ggcgctgtcg cggtgggtgg
     7441 gtggtcacga ggtcatccgt gggggtggtc ggcgtggtcg tcgaggcggt aggcggcggc
     7501 ttggaggccg tacagctcgg cgtacaggcc gccgagggcc atgagttcgg tgtgggtgcc
     7561 ctgttcggtg acgcggccgt ggtcgaggac gtagatgcgg tcggcgtagc ggacgctggc
     7621 caggcggtgg gtgatcagga cgatggcgcg gccgtcggcg tgcttgcgga tgcgttcgaa
     7681 cagggcgtgt tcggcgcggg cgtcgagggc ggaggtgggt tcgtcgaaga tgacgagttc
     7741 ggcgtcgcgg tagaagccgc gggccacggc gatgcgctgc cactgcccgc ccgacaggtc
     7801 gtggccgccg cggaagcggc ggtcgagcag ggagtcgtac ccgtgggtga gggtggcgac
     7861 gacctcgtcg gcgcctgcgg cggttgccgc ttcggcgagg cgtgcctggt cgagggggcg
     7921 tcccatgagg atgttctcgc ggacggtcag gggccagcgg gtgtggtcct gggcgatgac
     7981 ggagatcagg ccgcgcaggt cgaggcgggt gatgtcggcg ccgttccagc ggatggcgcc
     8041 ggactgcggg tggtacaggc cggcgaggag tttggccagg gtggtcttgc cggagccgtt
     8101 ctcgccgacc agggcgatga cctctcctcg ggcgacggtg acggcggcct cgcgcagggc
     8161 ggggcggtcg gcgccggggt aggtgaaggt gacgtggtcg gcggtgaggc gggcgagccg
     8221 ggccggggcc gcaggtgtga cgtccgtccc ggtgggtgct tgcgcggggg gtgtggtgcg
     8281 ggtggtggcc agggcgtgga aggtgaggta gtcgccgaag tacagtccgg cctcgtacag
     8341 gcggttgagg gtctggacga ggccggccag ggaggtctgg ccggtgcgga tggccaggac
     8401 ggcggtgccg gcgacggcga gcgggatgac gccggcggcc agcagcgtgg cgagcgccgc
     8461 gtagacgccg agggtggcgg cgccggtgag caggtcgccg ccggccttga cggtggtgcg
     8521 gcggcgggcg acgtcgagtt ggacgcgctg ttcgagggcg gcgaccttgg cgtattcggc
     8581 gagcaggaag tcgcgcaggt cgaaggctcg gacctcggcg gcgggctgcc gttcggccat
     8641 gaggtcggac agcatgaact tgcggcgccg cgcggctgac aggcggtaga aggcctggta
     8701 gccgagtttg ccggcgcgga cggcggccca tccggcgggc agcgcggtga ggagcagcag
     8761 cggcatcagc agggggtgga gcaggccgag tgcggcggtg gcggaggcga cgccgacggt
     8821 ggcggtgagg gcggcgatgg tggtctcgac gacggtggcg gtgtcgggga ctccgctgtc
     8881 gcgggcgcgg cgcatggcgt tgtggaagtc gtcgtcgtcg aaggcggcca ggtcgacgcg
     8941 ggtggtcagg tcgagcaggc gggtttcggc gaggcgttcg acctggggtt tgaggcgggc
     9001 ctgggcccag gtggcggcgg tcaggagggc gccgcgcagg gtggcggcgg ccgcgaggag
     9061 ggccagggag ggcagggcgt cgcggacgcg tccgggggtc gggccgccgg cgaacaggga
     9121 ggtcaggacg tcggaggtgg cgacgaagcc gtagacggtg aacgctccgg ccaggacgtt
     9181 gccggcgagg gcgacgacgg tgtcgcggcg gccggcctgc caggccaggc gcagggcgga
     9241 ggcgacgagg aagggcaggc ggcgggcgat ggcggccagg ccggcgttga ggagttcctc
     9301 gtcgtgggtc tcccagtagg ccgtctccag gccggacctg tcgtccgggg cggtgtcgcg
     9361 tctgtcgtcg ggttcgtcgt cgggtttctg gtgcggttcg gtgctcgtgg ccgtgtgtcg
     9421 ccacgtcccc caaagtttca tccgagctgc gttctccggc ggaccacccg gccaatgtag
     9481 gtgaagtcat ctggcgtgta aaggtgcctg gaaaggggct ccggcgggtg cggggcgggt
     9541 ggcgggttgc ctgtggacag gcctgccggg gtgtgcccat aatgccagag tttggccgtg
     9601 acccggcatt gtgggtcgcg gtcatggccc gggtaattgc gtctatccga tgtttttccc
     9661 gggtgtggga cccatcccgg ccgttcaccg cggccaaaga aaggagccct catgtcggta
     9721 ctggcgctgg agccccgcga cgcgggcgtc ctcgagttcg aggacttcga cgtcgacttc
     9781 gacggcgagc tcgccaagct gctgcacggc ccgcaggcct gcgcgaacac ctgcaagcgg
     9841 acggtgtgca gcagcttccc ctgctgccct tccatcgtct gacccggaaa tgacggcgtg
     9901 cggttccgcg atttcgcggg gccgccgctt ccgcgtggcc ggataatccg gcgggttttt
     9961 ctcgacgttt tcagtggagt ctgtcaccgg agtggagagt atggccgcgt ctgtcgccgt
    10021 cgatgtgctg gaaattctta ccggattcgc tgccgagcat gggcgtgatg tttatgagga
    10081 cgacacgtgg gtgagcgtgc actccccttc cggcggcatt ccggcgcagg ggtggaagct
    10141 gcacgtctcg gcgcgtcccg gcacgctggg cgagacgatc gagcgggcgc tgccggtgct
    10201 gctggagcac ggttgcgact tcaaggtggc gcgttcggcc gagacgctca gggagctgaa
    10261 ctccggcgac gtggacgcgg gcgcggtggg caaggcgatc accgcctatc cggcgcagga
    10321 ccgggtggtg gcgctggggc acgcgctggc ggacgcgctg gccgggatgg cggggccgcg
    10381 gatcgtgagc gaccggcggg tgcgccagga cgcgccggtg tactaccggt acgcgccgtt
    10441 cgcgccgcag taccgggtgg acgacaacgg cgatttcgag ctggtcgtgg tggggccgga
    10501 cggtgagcgg ctgccgggcg cggcggggcc ggagttctcg tgcccgccgt gggcgtccga
    10561 cccgttccgc ccgcccgccg ccggcgcggc ccggcaggcg agggaacctg cgagcgagac
    10621 ggcgccggcg cggctgatcg gcaaccggta ccgggtcacc tccggggtgg tgcgcggccc
    10681 gcgcggcaac gtctaccgcg ccgccgaccc ctcgggccgg ccggtcgtcg tcaaggaggc
    10741 gcgcgcctac gtcggggaga acccgcaggg ctgggatctg cgcatgtacc tgcgtaacga
    10801 gctgcgggtg ctgaaggcgc tgcgcggcgt ggagggggtg ccgcgcccgc tggaccactt
    10861 ccggcacggc gacgacgagt tcctcgtgat gacggacgcc ggcagcctgg acctgaacag
    10921 gttcgtgggc gagcggggcc tgttcaccga cggcggcggc gagcgggacc tggccgcgct
    10981 ggccgggcgg ctgctggcgg tgctggacgc ggtgcacggg cggggcgtgg tggtcaggga
    11041 tctgtcgccg aagaacgtgg tgatcggtga ggacggccgg tgcacgctga tcgacttcgg
    11101 caacagccgg tacgaggggc tgcagctgcc ggggtggacg cgcggctaca gcgtgccgga
    11161 ccagcgttcg gggcgtgact ccgagccgtc cgacgactac ttctcgctgg gggcgacgct
    11221 gttcttcgcc tgcgccggga tgaacccggt catgatcgac gcggatccgg tgcggaacct
    11281 ggagcggacg ctcatgtgcc tggagcggct gttccccggt gtcaggacgg gggtgcgggg
    11341 gctgctgccg cgcctgatga gcctggaggc ggccgagcgc ggccgggcgg ccgacgacct
    11401 gcgggcgggg cggctggacg gccgggaccg tacggtgatc gcggtgccgc gctggagcgg
    11461 ggagcttttg tcgcgggtga tggagcacac gacgcgggcc tgcgtcgctt tcgccgaggg
    11521 gttgatggag gctccggagg gggcgcgcag gtcgagcccg ccggtgacga acgtgtacgg
    11581 cggctcggcg gggctgggca tggagctgct gcaccatcgg cgggccaggg cggtgggggt
    11641 ggatctggcg cggtggacgg cgcgggtgat gccgcctgtc gtgttgccgc cggggctgta
    11701 cttcggccgt acggggacgg cgttgttcct ggcggcggcc cggtcgtcgg gggcgccgga
    11761 gctggagcgg gcgctgccgg tcgagctggg cggcgatcag cgtgccgacc aggcgcacgg
    11821 ggtggcgggc atcggcgcgg gccatctggc gctggcggcg ctggagcggg acccgcgcca
    11881 cgtggaggtc gcggccgagt gcggccggct gctgatggcg ggcgaggtga gccagtcgcg
    11941 ggacgcggtg gcgccggcgc agccgggcac gggtgtggcg gtggagtcgg cgttcgcgca
    12001 cggcgcggcg ggttgcgcgg acttcctgct gtcgctgtgg gaggcgacgg gtgacgagcg
    12061 ggtggggcgg gcggcggccg ggcggttcgc ggagctggcg gaggtggccg gggtgctgct
    12121 ggaggagctg gcggggcccg cggccaggcc gatgggggcg tcgtggtgcc aggggatgtc
    12181 gggtgtcgca ggggcgctgg cgcacgccgg gcgggcgctg ggtgaggacc gctacgtgga
    12241 gctggccgag cggggggcgc gggcgtgcct ggcgctggcg ccgcaggcgt gggtggtgtc
    12301 gcagtgctgc ggtctggcgg ggatcggcga gtgcctgatc gatctggcgt tgctgacggg
    12361 cgacgagttc tactggcggg gggccgagga ggtcgcggtg ctgatgctgg tgcggggcgg
    12421 cggggagccg gacgcgccgg tcttcccggg caacgacctg gacaaggcgg ggttcacgtg
    12481 ggcgacgggg gcgtcggggg tgctgtcgtt cctgcggcgg ctggatcagc ggtcgggcga
    12541 gcggctgtgg acggcgtcct ggcggctgcc cgggtgaggc cggggtgagg ccggggtgag
    12601 gccgggggcg gtgcccgcct gccgggtgga ccgtcttgtc gaggaaggcc ggcgggcggg
    12661 cgccgggtcg ggcggctcgt cccccgtgct gggtcaggtg gaggtggcgg cggtgtggcg
    12721 ggcggcgacg tcggccctgt cgaccaggtc ccacagccgc tcgacgtagt cggggtggac
    12781 gttgcggtac tgcagggggc cttgaaggcg tcgaaggagc cgacagggcg acaagggtgc
    12841 gcgggcaggc ggaaggggcc cggcaggcgt gtccgccggg cgccggcgga gggcgtcagg
    12901 cggagggcgt caggcggagg tggcgcggat gagggccagg tcgtcggggt cgacgggtac
    12961 gccgttggcg gcggcggcct gggcgagcag cagctcgccg gtgtggccga tgtgggtgcg
    13021 catggcggcg gccacggcct cggcgtcgcc ggcctccagg gccgcgagga tgggctcgtg
    13081 ctcgcgggcg atgtcgggca gggagcgtga gcggtcgacg gtggaggcgc cgagggtgat
    13141 ggtggcgtcg cgcaggttgt cgacgatgcc gacgagcttg ccgttgtgcc cgccctgcag
    13201 cagcaggcgg tggaaggcgg cgtcgtggcg catgaagcgc ggctcgtcgt gggcggccgc
    13261 ggcctcgcgc atctcctcca gttcggcgcg catggcctgc agcagggcgg ggtcgcggcg
    13321 gtgggcggcc agccgggcgg cgggcacctc cagcagcagc cgcaggtgga agacctcggc
    13381 gatctccttg gggtcgctgc gcaggacgcg gaagccgcgg ctgcgctcga agcggacgag
    13441 cccggcttcg gccaggcgca gcatggcctc gcgtacgggg gtgcgtgaga ccttgagctc
    13501 ggcggcgagc tggtagacgg agtagagctg tcctgggcgc agctcgccgg agtggatggc
    13561 cttgcggacg gactcgaaga cctgatccgt cagggtggac gtgccgtcga ccgcttgcac
    13621 cgtggccctt tcgcctcgcg attcttccgc ctgaagccta ctcaaaccga catatcgatg
    13681 gttagcatgc agcatgctac attccggtaa tccgccgttc tggatggggg aacgcccgtg
    13741 aaactccacg tactcgactg cggggcgatg agctgcgacc tgacctggct gctgctcaag
    13801 cccggacgca ccatcaggcc gagggccgag cgcgaccgcc cggtcgagtg gtacccgtgc
    13861 accacccacg ccgtcctcgt cgagaccgac gagggatcgc tgctgtggga caccagctgc
    13921 ccgcgcgact gggagacccg ctggatcccc accgggctgc aggagttctt cccctacgac
    13981 caggtctccg acgagcagta cctcgacgcc cagctcggac ggctcggcgt cagccccgac
    14041 cgcctcgact acgtggtgct gtcgcacctg cacttcgacc acgccggcaa cgtgcgcatg
    14101 ttcgccggca ccggggcccg actggtgtgc aacgacaagg agaaggagtt cgccttcggc
    14161 tacgagggcg ccttcgacgg cgcgcacctg aaggccgact acgagggcct ggacttccag
    14221 acggtctccg gcgacaccga gatcctgccc ggcgtgaccc tcatcgaggc gcccggccac
    14281 accgtgggca ccatggccat gaaggtggac ctgcccgaga ccggaaccat gatcttcacc
    14341 tcggacgccg tctacatggg cgactcctac ggcccgccgg ccaccccggc ggccatcgtc
    14401 aacgacctga ccgcctggta cgcctccgtg gagaagatcc gctccatcgc cgagcgctcc
    14461 gacgcgacgg tgatcttcgg gcacgacgcc gagcagctgc gctccctgcg caccgccccc
    14521 gacggcttct accagtagca aaggacgatc gagtgttcac cgcgcccagc aaccccgagt
    14581 ccgtcttcac ctacggcgcc ccggcgctga agttcggcac cggcgcctcc gccgagatcg
    14641 gcttcgacct cggccagtac ggcgtccgcc gcgtcctggt cgtcaccgac gcccgcgtgg
    14701 ccgccaccgg ctccccggcc aggatcgccg aacagatcgc cggctacggg atcgaggcgc
    14761 acgtctacga cggcgtgcac gtcgagccga ccgacgcgag ccttcaggcg gcgatcgagc
    14821 acgcccgggc gagcggcccg tgggacgcct tcgtcgccgt cggcggcggc tcggccatcg
    14881 acaccgccaa ggccgtcaac ctgctgacca ccaacccggg cacgctgatg gactacatca
    14941 atgtgccggt cggcggcgga cgcgccccgt ccgagccgct caagccgctg gtcgcggtgc
    15001 cgaccaccac aggcaccggc tcggagtcga ccacgatctg cgtgctggac gtgctggagc
    15061 tgaaggtcaa gaccggcatc agccatgcca ggctgcggcc ggtgctcgcc gtggtcgacc
    15121 cggagctgac gatgacccag ccggccgggg tgaccgccgc cgccggcatg gacatcctgt
    15181 gccacgccct ggagagctac accgcccgcc cctacacctc ctacgagcgc aagaagccgc
    15241 aggagcgggt gccgtactgc ggggccaacc cggtggccga catgtgggcc gagcaggcgc
    15301 tgcggctgct ggcgcagtcg ctgcgcgccg cggtgcgcga cggcggcgac gccgaggcca
    15361 ggggccggat ggcgatggcg gcgacgttcg ccgggctggg cttcggcaac gccggcgtac
    15421 acatcccgca cgccaacgcc taccccatcg ccggacgggt gcgcgacttc cacccggacg
    15481 gctacccgaa ggacgagccg atggtgccgc acggcatggc ggtggcgctg tcggcgccgg
    15541 aggcgttcag gttcaccttc gaggccgacc ccggccggca cctgcgcgcg gccgagctgc
    15601 tcgccccgga cgccgagcgg ccctccgacc tggccggcca cctgccgtcg gtgctgcggg
    15661 cgctgatgcg cgacatcggc atcccgaacg gcatcggcgg cgtcggctac ggcgagcagg
    15721 acgtgcccgc gctggtcgag ggcgcgatga agcagcagcg gctgctggcc accgctcctc
    15781 gcccggtcgg cgaggaggac gtggcggcca ttctgacccg ttcgatcgcg ttgtggtgag
    15841 gtgctgagga tggcgatcta cgagttgcgt tgcgtgcgcg ggcaccgctt cgaggtgatc
    15901 cagtcgttca ccgcgccgct tcccgcctgc cgggagtgcg gggcggagac gggcaaggtg
    15961 ccttcgacgt tcggcttcgg ggggcgggcg tcgggggcgc tgccgccgcc gccggagctg
    16021 atgccgcaga cgtggcgggg gacgtacggg gccgaccgcg agtacgtgac ggggctgcgg
    16081 cgcgcggccg agtcgcggcg ggcgctggag gagcgcaacc cggagctggc gggtgaccgc
    16141 aggccggtgc tggcgcacga gggccggttc gaggcggcgc cgctgcgggc gggcgacccg
    16201 ctgcccctgg gcggcggcca cacctacggg cacactcacg gtcacaccca tgggcacggt
    16261 cacgggcaca ctcacgggca cggtcacggg cacactcacg ggcaggggca cggcggggtg
    16321 gccggggctc ccgccgcggg ccgggaaggg gactcctcct gaaccccgcc gacctcgccg
    16381 aggcgctgcg ccgggccggc gtcgccgacg tcgacgcctc ctcccggcgc cgcgccgagt
    16441 actcctccga cgcctcgctg taccgggtgc cgccgctggc ggtggccttc ccccgccacg
    16501 ccgacgaggt ggccgccgcg ctggcctggt gcgcggccga gggcgtgccg ctgaccgcgc
    16561 gcggcggcgg cacctccatc gcgggcaacg cggtcggccc cggcctcgtc ctggacttct
    16621 cccgccacat gggccgcatc accgcgttcg acccgcagga gggtacggcc accgtcgagc
    16681 ccggcgtggt gctggacgac ctgcagcgcc gcgccgcccc gtacgggctg cgcttcggcc
    16741 cggacccgtc cacccacagc aggtgcaccc tcggcgggat gatcggcaac aacgcgtgcg
    16801 gctcgcgcgc cctggcctac ggccgcaccg ccgacaacct gctggccctg gacgtgctga
    16861 ccggcggcgg cgagcgcctg tccaccgacg cggcgggctc gtcgccggcg ctgcgcgccc
    16921 tgcgggaggt cgtggggcgc aacctggccg tcatccgcac cgagatgggc cgcttctccc
    16981 ggcagatctc cggctactcg ctggagcacc tgctgcccga gaacggcttc gacgtggcca
    17041 gggcgttcgc cggcagcgag ggcacgtggg gggtgctgct gggcgcgaag gtgcggctgg
    17101 tgcgcgcccc cgcccacacg gtgctcgccg tgctcggcta ccccgacatg gccgccgccg
    17161 ccgacgcggt gccggcgctg ctgccgcacc ggccggtcgc gctggagggg atcgacgcgc
    17221 gcatcgtcga ggcggtgcgc cgccgccgcg gcgaccacgc cgtgccgccg ctgccgggcg
    17281 gccgggggtg gctgctcgcg gagctgggcg gctcctcccc cgccgaggcc ggggccgccg
    17341 cccgcgcgct ggtcgccggg tccggcgcgc tggacagcct gctggtcgcc gacgccgcgc
    17401 aggccgccgc cgcgtggcgc atccgtgagg acggcgccgg cctgtccgcc cgcacccctg
    17461 ccggagcgcc cgcgcacgcc gggtgggagg acgccgcggt gccgcccgag gggctcggtg
    17521 cctacctgcg ggtcttcgag gagctgatgg ccgggtacgg gctgaccggc ctgccgtacg
    17581 ggcacttcgg cgacggctgc gtccacgtgc gcatcgactt cccgttcggc agggccgacg
    17641 gcgcggcggt gttccggtcg ttcctgaccg acgccgcgcg cctggtggcc gagcacggcg
    17701 ggtcgatgtc gggcgagcac ggcgacggcc gggccagggg cgagctgctg ccgctgatgt
    17761 actcccccgc cgcgctggag gcgttcgcac aggtcaaggc ggtcttcgat cccggtgagg
    17821 tgctgaaccc gggcgtgatc gtgcgtcccg ccccgctgga tgaggcgctg cggctgcagc
    17881 cgccgccccc gcgcgcgagc gggctggccc tgcgctaccc gcacgacggc ggcgacctgt
    17941 ccgcggcggt gcaccgctgc accggggtgg gcaagtgccg ttcccacgcg gccggtcccg
    18001 gggcggtgat gtgcccgtcg taccaggcga cgcgggacga gaaggactcg acgcggggcc
    18061 gggccagggt gctgcaggag gcggtggcgg gcaggctgcc gggcgggttg cgcgcgccgg
    18121 aggtgcggga ggtgctggat ctgtgcctgt cgtgcaaggg gtgcctgtcg gactgcccga
    18181 ccggggtgga catggcgacg tacaaggcgg aggtgctgca ccagagctac cggggccggc
    18241 tgcggccggc ggtgcactac agcctgggct ggctgccgcg ctgggcgcgg ctggcgtcgc
    18301 tggcgcctgc cgcggtcaac gcggtgctgc gggtggggcc ggtggcggcg ctggccaagc
    18361 gggccggcgg gatcgacgcg cggcggccgc tgccggcctt cgccgggcgg cgcttccgcc
    18421 gcctgcgtcc cgcgcgggcg ggccggccgg gtgggacggc gggagccggc gggcggcggg
    18481 tgctgctgtg ggtggacacc ttcaccgacc acttcgcccc gcaggtggcc gaggccgcgg
    18541 tgcgggtgct gacgcgggcc gggtgcgagg tggcggtgca gcgtgacagc cagtgctgcg
    18601 ggctgacgct gatctccacc ggccagctgg acgccgccgg gcggctgctg cggcgcacgg
    18661 tggcggcgct ggcggggcac gcgcgcgccg ggacaccgat cgtggcgctg gagccgtcgt
    18721 gcacggcggt gctgcgctcc gacgccgccg acctgctcgg cagcgacagt gccggtgaag
    18781 gtgccggtga aggtgccggt gccggtggag atgacgtggc ggtggtggcg ggggcggtgc
    18841 ggacgctggc ggagttcctc ggcgagctgc ccggctggcg gccgccggac ctgtcgggcg
    18901 tgcgggtgct ggcccagccg cactgccacc accacgccgt gatgggctgg gaggccgacc
    18961 gcgcgctgct ggcgcgggcg ggcgcgcagg tgagcgccgt gggcggctgc tgcgggctgg
    19021 ccgggaactt cggcatggaa cgcggccact acgaggtgtc ggtggcggtg gccgagacgc
    19081 agctgctgcc cgcggtgcgc cgggccgcgc cgggcacggt gctgctggcc gacgggttct
    19141 cctgcaggac gcagctcgac cagctcgcgc acgtacgcgc cttccacctg gccgagctgc
    19201 tggcggggcg ggctcaggcg gtgccgggct ccggcgggta ggggtggacg gcggtgaccg
    19261 cgccggcggg cagcggcccg tacaggtggg ggaagccgcc ttccacgcgc acgtccaggc
    19321 cggtggtgtc gatgtgcagg acgaccagcg gttcggtcac ggccgtgtag aaggtgtcgt
    19381 ggacggtgcg cagctgggcg gcgtcgcggc tgcagtggat gaagccctcc tgctccaggg
    19441 tgcggccgag ggtggagacg cggtactcgc cggccgggcg ggcggcctcc cagtcggagc
    19501 gcagcgccag gtgcagcacg ctcgccgggg cgggcgcggc gggccattcg cgggcgagca
    19561 cggcgtagac gatctcgctg gtccactcgc ccttgacgac ctcgttctcg acgaggtggg
    19621 cctcctggcg catgccgagc ttgcgcagca cgctggcgga ggcggtgttg cgggcgtcga
    19681 gcctgccgac gatgcggtgc aggccgagct gctcgaagcc caggcgcagc atctcgcggg
    19741 tggcttcggc ggcgtagccg cggcggtggt gcgccgggtg caggacgtag ccgatctcgc
    19801 cctggcggtg ccggcggctg gtccaggcga gcagggtgtt gccgatcacc tcgccggtgg
    19861 cggtgagcgt gatggccagg tcgatggcgt cgccctcctc gcgcagcgcg gtgcgggcga
    19921 tcttcttgtc gaggaagccg cgggcggtgt cgcggtcgcg gggctcccag tagaggtagc
    19981 gggcgacctc gggcagggat tcgtaggcgt ggacggcgtc gaggtcgtcg ggggtgaagg
    20041 ggcgcagcgt gagccgctcg gtgctgatcg ggtagcgggg ttcgagcacg gggcgcaagt
    20101 gtaggcaggg gtcaggcggg ccgcaaagcg ttttcgacgg cggcgtcgag cagggcgcgg
    20161 gcgtcggcga gggggcgctg ctcgacgacg tgctccagcc acagggccga cagggtggtg
    20221 tagacgaggc gggcgcgcgg gtcggtctcg ggcagggtga gggcgtcggc gacgaggcgg
    20281 acgcagccgt cggtccagcg gcgggcgatg cgctgcagcg cggggtcgcg tccggcgtgg
    20341 acgtacagct cccacaggcc gagctggcgg gcgcggtcgg cggcggcgac ctgttcgggc
    20401 agggcgcgca ggccgtggcg ggcgacccag tcgcgggtgg tggccagttc ggcctcgacg
    20461 agctgggcga acgcctcggc caggagctgg tcgcgtgagg cgaagtagta ggtggtggcg
    20521 gccagcggca ggcgggcgcg gcgggcgacg ttgcggtggg tgacggcggc gaagccgcct
    20581 tcggcgagca ggccgacggc ggcggccagc aggtgggcgc ggcggcggcg gccgcgctcc
    20641 tggaccgggg gcgggccggc ggagggggcc ggcgcgggct cctgctgggg gttcaatggc
    20701 cacctgcgag gttgaggacg acgacgccac cgatgatcag gaggataccg ccgatcttgg
    20761 ccgggttcag tgactctccc atgaaggcgg cgccgatgag cgcgatcgcg gcggtgccgg
    20821 cgccggacca gacggcgtag gcggtgccca tctccagctg gagcttcagc gcgcgggcca
    20881 gcagcacgaa cgagacgagg tagccggcgg cgacgacgac gctccagccg aggtgggtca
    20941 ggccgttgct gagtttgagc gcggaggtgg ccaggacctc cgaggcgatg gcgaacgcga
    21001 gcaggatcca ggccatggca tacccccgga cgggtaaata gtggtacagg tgtcctagtt
    21061 tagcgccgcc gggtgtggct gatccgcttg aaaagcgagt cgaaaacgtg ttccactgga
    21121 gggcgtgggt tgggacgcgc ttccgctggt cgacgccgtc gacgagcgtc cgccgatcga
    21181 gcggcgggcc gtcgtgcgcg acgggttcta cgagacccag gcccgcgccg tgatcgagcg
    21241 ggtgcccgag acggccggca tcgcacagtc ctgggccctg tccccctacc gcggctgcgc
    21301 ccacgcctgc cgcggctgcg gcgcccgcgc cggtcaccgc aggctcggcc tcgacgccgg
    21361 gcgcgacttc gacacccggg tggtggtcaa ggccaacgcg gtgtcccggc tgcgcgccga
    21421 gctggcccgc tggggcggcg agccgctggc ggtcggcgtc agcggcgact gctaccagcc
    21481 ggccgaacgc gtctacacgc tgatgcccgg cctgatcgcg gcgctgggcg aggccgcggt
    21541 gcccttcacc gtctacacca ggagcccgct ggtgctgcgc gacgccgagc tgctggccga
    21601 ggcgggcgcg caggtggcgg tgtccatcgc gttcgtcgac gagcgcatca ggcgcgccgt
    21661 cgagcccggc gcgggcggcg cgcagtcccg cctcgagctg gtctcggccc tggtggaggc
    21721 gggggtcgac tgccgggtgc tgatggcgcc cgtgctgccg ctgctcagcg acgccgccga
    21781 ccagctcgcc gcgaccgtgc ggcgcatcgc cggcgcgggg gcgcgggggg tggagccggt
    21841 ggtgctgcgg ctgccgccgg gcacgcgcga gtggtacctc ggctggctgg ccgaggccca
    21901 tccgcacctg gtggcccgct acgaggagct gtacgaccgg gcgggcctgc cctcccccgg
    21961 ctacgagcag cgcatcaccg ggcagatcgc gcagctgtgc caggtgtacg gcctgccctg
    22021 cggcgctccg ccgcctccgg tgcgccgccc gcgcttcccg cagctgtccc tggtctgacc
    22081 tcggcgcggg gccgggccgg aaaatcggtg gacggcgctg ttagcgtgcc gggtatgccg
    22141 atcatcgatg tcgaccgttt cgccgccgaa ggcttcgcca aggtcgaggc cgtggtgccg
    22201 cgggaggtgg gcgacgcggc ccgcgccctg ttgtgggagc gcatcggcct gtcgcccgac
    22261 gacccgtccg ggtggaggca gccggtcgtg tggacgtccg acctgacggg cgagggcccg
    22321 ttcgggcaga tcgcgtggtc ggagcggctg ggcgaggcgc tggacctggt ggccgggccg
    22381 ggcggctggc tgccccgggg cagcctgggc aacatgccgg tccgcttccc ccgggtggcg
    22441 cccgccgacg accgcggctg gcacatcgac gccaacaccc ctcgcgccga cggctcgtgg
    22501 ggcgtcagcg gccgcccgca cacgctcctg ctgctggtgc tgctgtcgga cgtgggcgag
    22561 cacgacgcgc ccacccg
//
