LOCUS       NZ_BBOK01000023        15522 bp    DNA     linear   CON 17-AUG-2024
DEFINITION  Streptomyces sp. NBRC 110030, whole genome shotgun sequence.
ACCESSION   NZ_BBOK01000023
VERSION     NZ_BBOK01000023.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. NBRC 110030
  ORGANISM  Streptomyces sp. NBRC 110030
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Katano-Makiyama,Y., Hosoyama,A., Hashimoto,M., Tsuchikane,K.,
            Uohara,A., Kitahashi,Y., Ohji,S., Ichikawa,N., Kimura,A.,
            Yamazoe,A., Komaki,H., Igarashi,Y. and Fujita,N.
  TITLE     Whole genome shotgun sequence of Streptomyces sp. NBRC 110030
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 15522)
  AUTHORS   Hosoyama,A., Kimura,A., Ohji,S., Ichikawa,N., Yamazoe,A. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2014) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 97x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina HiSeq 1000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001417675.1-RS_2024_08_17
            Annotation Date                   :: 08/17/2024 02:44:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,240
            CDSs (total)                      :: 7,152
            Genes (coding)                    :: 7,019
            CDSs (with protein)               :: 7,019
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 4, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 45 of 133
            Pseudo Genes (incomplete)         :: 107 of 133
            Pseudo Genes (internal stop)      :: 8 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:33:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 15522
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBOK01000023.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     protocluster    1..15522
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[<0:11395](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(<1..11395)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     gene            complement(<1..6443)
                     /locus_tag="APK71_RS35225"
     CDS             complement(<1..6443)
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (28-52). E-value:
                     1.8e-13. Score: 41.8. Matches aSDomain:
                     nrpspksdomains_APK71_RS35225_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (59-487). E-value:
                     2.1e-172. Score: 565.8. Matches aSDomain:
                     nrpspksdomains_APK71_RS35225_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (610-897). E-value: 3e-109.
                     Score: 356.9. Matches aSDomain:
                     nrpspksdomains_APK71_RS35225_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (985-1154). E-value: 1e-55.
                     Score: 180.6. Matches aSDomain:
                     nrpspksdomains_APK71_RS35225_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1450-1629). E-value: 3.2e-61.
                     Score: 198.4. Matches aSDomain:
                     nrpspksdomains_APK71_RS35225_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1727-1813). E-value: 7e-33.
                     Score: 104.8. Matches aSDomain:
                     nrpspksdomains_APK71_RS35225_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1834-2147). E-value:
                     3.8e-130. Score: 426.5. Matches aSDomain:
                     nrpspksdomains_APK71_RS35225_PKS_KS.2"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082177.1"
                     /locus_tag="APK71_RS35225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_159042941.1"
                     /sec_met_domain="mod_KS (E-value: 4.6e-222, bitscore:
                     725.0, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.5e-110, bitscore:
                     356.9, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 7.7e-63, bitscore:
                     199.3, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.1e-16, bitscore:
                     49.0, seeds: 164, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 5.1e-88, bitscore:
                     282.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVRDSRTEHGADGARDEGADRTGQADQDRLLGYLKRVTAELHQT
                     RQRLHEAGEDEREPVAIVAMSCRYPGGVRSPEDLWRLVADGTDAIGPAPTDRGWDLGAL
                     LDTDPDGTGTGFTGEGGFVHDAGAFDAGLFGMSPREALATDPQQRILLELAWETFERAG
                     LAPDALRGRDVGVFVGTGGQDYYDDLDADAVSDVVDGYLSTGTSAAVLSGRLSYTFGLE
                     GPALSVDTACSSSLVATHLAAQALRRKECSLALAGGAMVMSTPTPFVAFGKQRGLAPDG
                     RCKPFAEQADGTGWSEGAGLLLLERLSDARRNGHRVLAIIRGSAVNQDGASNGLSAPSG
                     PAQQRVIRQALAAAGLSASEVDAVEAHGTGTTLGDPIEAHALLATYGQDRPADRPLWLG
                     SIKSNIGHAQSAAGVSGIIKMVQALRHDTLPRTLHAAEPSSHIDWSAGRVRLLDEARPW
                     PRSATPRRAGVSSFGISGTNVHLILEEAPAPDPEPATGDGPDRGGAGAPDGVPVPLVVS
                     GRGAEALRAQAARLLEHAEHAEHAEHGTHDGDVDTALVDTAYSLATGRASLDHRAVVLA
                     TDRTTARRGLAALSAGESAPNTFSGTATNGLTAFLFTGQGSQRPGMGEELYAAFPAYAE
                     ALDTVCEAFDGLLGRPLREVLTARPGTPEAALLDETEYTQAALFAVEVALFRLLESWSL
                     LPDFVAGHSIGELAAAHVAGVFSLADACTLVAARGRLMQALPAGGAMVAVRATEEETAT
                     LLHGRTDVAVAAVNGPRSVVISGAEEAVLEVAALLEERGSSTRRLRVSHAFHSPLMDAM
                     TADFRKVADSVEYRAPHIPLVSTLTGRRATAAELCSADYWVRHARETVRHHDAVRSLAD
                     EEVTRFVELGPDGVLSAMAEETDTSGPAHDAPAAGPAVLRVPLLRAGRPGTATLLSALA
                     RMYVSGLAPDWEAVFAGLGARRTDLPTYAFRHRRYWLDERAAGRGPAAVGLDPADHPLL
                     GALTVLADEGGAVLTGRLSTTTRGWLAEHRVHGAAVLPGTAFVDLALWAGEQVGHPHLD
                     ELTLLAPLPVPAGDGIRIQVVVGAADDAGARSFGVYSRADDAPGQESGTPEWTHHAGGV
                     LTGRREDHARLDPAPWPPSGARPVALDDLYPRLAAAGLDYGPSFHGLRAVWQHGEDVLA
                     EVALPAEAGHDSARHALHPAVLDAATHALAASLGTDATSSGSAGTPTGASAPGRLPFTW
                     SGVSLYSRGASMLRVRFTPTTADAYTADIADSTGSPVARIDSVTFRAAGTDERLPVFRM
                     DWVPAAGQDRAGRDTAASADGLDHTVRILPAGGPPADGQDTFEAVRATLHKTLAALQEH
                     LNAPSEDQPRLVVVTTGATAGDAATEIDLAGAAVHGLVRSAQTEHPGRLVLLDLESGTD
                     AADAAAFLPALLDSGEPQAAVREGTLHVARLSRVSTGSEDAGAAFPPHGTVLVTGASGA
                     LGGAVAHHLVTTHGANSLLLLSRTGEADPRLAALATRLRELGAVVTTAACDVADRDQLA
                     AALATVPADRPLTGVVHAAGVLDDGVVSSLTPERVDTVLPPKVAGALHLDELTRDADLT
                     AFVLFSSVSGILGAPGQANYAAANTFLDALAARRRTQGRPALSLAWGPWLADTAPVGED
                     DGTTAVHGMTAGLGDTYRARMTRSGVRPLSAAEGLGLFDAALRATEPTVIPAGLGAAHL
                     RGPAARDARRPVKGGTASTGSTPGVPYADRLRGLPESEQHTMLLDLVRGHVAAVLGHDS
                     PLAVEPDRGFHELGFDSLTAVELRNGLATATGVRLPATLVFDHPTVTALVRHLQEELVG
                     TAEGPVSSVPSSPATHDEPIAIVGMGCRFPGGVDSPEGLWRLVSEGTDAIGEFPEDRGW
                     DIDGLYDPEGVRPGSTYVRHGGFLKDAADFDADFFGISPNEALTMDPQQRLLLESSWEA
                     LERAGIVPGSLRGSGTGVFAGVQYHDYVGSNSTGAVVSGRVAYALGLEGPAVSVDTACS
                     SSLVGLHLAVQSLRRGECSLALAGGVTVMATPETFVEFSRQRGLSVDGRCRSFGAGAGG
                     TGWSEGVGVLVVERLSDARRLGHEVLAVVAGSAVNQDGASNGLTAPNGPSQQRVIRAAL
                     ADAGVSAVDVDVVEAHGTGTVLGDPIEAQALIAAYGQG"
     source          1..15522
                     /culture_collection="NBRC:110030"
                     /db_xref="taxon:1550033"
                     /mol_type="genomic DNA"
                     /note="contig: scaffold00032"
                     /organism="Streptomyces sp. NBRC 110030"
                     /strain="NBRC 110030"
     region          1..15522
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     cand_cluster    1..15522
                     /SMILES="C=CC(C)C(O)C=CC(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     aSDomain        complement(3..941)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: False"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS35225_PKS_KS.2"
                     /domain_subtypes="Modular-KS"
                     /evalue="3.80E-130"
                     /label="APK71_RS35225_PKS_KS.2"
                     /locus_tag="APK71_RS35225"
                     /protein_end="2147"
                     /protein_start="1834"
                     /score="426.5"
                     /tool="antismash"
                     /translation="IAIVGMGCRFPGGVDSPEGLWRLVSEGTDAIGEFPEDRGWDIDGL
                     YDPEGVRPGSTYVRHGGFLKDAADFDADFFGISPNEALTMDPQQRLLLESSWEALERAG
                     IVPGSLRGSGTGVFAGVQYHDYVGSNSTGAVVSGRVAYALGLEGPAVSVDTACSSSLVG
                     LHLAVQSLRRGECSLALAGGVTVMATPETFVEFSRQRGLSVDGRCRSFGAGAGGTGWSE
                     GVGVLVVERLSDARRLGHEVLAVVAGSAVNQDGASNGLTAPNGPSQQRVIRAALADAGV
                     SAVDVDVVEAHGTGTVLGDPIEAQALIAAYGQ"
     CDS_motif       complement(33..77)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0014"
                     /evalue="8.00E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="APK71_RS35225"
                     /protein_end="2137"
                     /protein_start="2122"
                     /score="11.8"
                     /tool="antismash"
                     /translation="VEAHGTGTVLGDPIE"
     CDS_motif       complement(456..500)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0013"
                     /evalue="6.90E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="APK71_RS35225"
                     /protein_end="1996"
                     /protein_start="1981"
                     /score="18.1"
                     /tool="antismash"
                     /translation="GPAVSVDTACSSSLV"
     CDS_motif       complement(660..686)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0012"
                     /evalue="3.60E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="APK71_RS35225"
                     /protein_end="1928"
                     /protein_start="1919"
                     /score="7.3"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     aSDomain        complement(1005..1262)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS35225_PKS_PP.1"
                     /evalue="7.00E-33"
                     /label="APK71_RS35225_PKS_PP.1"
                     /locus_tag="APK71_RS35225"
                     /protein_end="1813"
                     /protein_start="1727"
                     /score="104.8"
                     /tool="antismash"
                     /translation="LRGLPESEQHTMLLDLVRGHVAAVLGHDSPLAVEPDRGFHELGFD
                     SLTAVELRNGLATATGVRLPATLVFDHPTVTALVRHLQEEL"
     aSModule        complement(1005..6266)
                     /complete
                     /domains="nrpspksdomains_APK71_RS35225_PKS_KS.1"
                     /domains="nrpspksdomains_APK71_RS35225_PKS_AT.1"
                     /domains="nrpspksdomains_APK71_RS35225_PKS_DH.1"
                     /domains="nrpspksdomains_APK71_RS35225_PKS_KR.1"
                     /domains="nrpspksdomains_APK71_RS35225_PKS_PP.1"
                     /locus_tags="APK71_RS35225"
                     /monomer_pairings="mal -> ccmal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(1557..2093)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N found: True"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS35225_PKS_KR.1"
                     /evalue="3.20E-61"
                     /label="APK71_RS35225_PKS_KR.1"
                     /locus_tag="APK71_RS35225"
                     /protein_end="1629"
                     /protein_start="1450"
                     /score="198.4"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: B1"
                     /tool="antismash"
                     /translation="GTVLVTGASGALGGAVAHHLVTTHGANSLLLLSRTGEADPRLAAL
                     ATRLRELGAVVTTAACDVADRDQLAAALATVPADRPLTGVVHAAGVLDDGVVSSLTPER
                     VDTVLPPKVAGALHLDELTRDADLTAFVLFSSVSGILGAPGQANYAAANTFLDALAARR
                     RTQGRPALSLAWGPWL"
     CDS_motif       complement(1602..1706)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0011"
                     /evalue="2.50E-21"
                     /label="PKSI-KR_m4"
                     /locus_tag="APK71_RS35225"
                     /protein_end="1614"
                     /protein_start="1579"
                     /score="68.3"
                     /tool="antismash"
                     /translation="AFVLFSSVSGILGAPGQANYAAANTFLDALAARRR"
     CDS_motif       complement(1989..2090)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0010"
                     /evalue="1.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="APK71_RS35225"
                     /protein_end="1485"
                     /protein_start="1451"
                     /score="17.9"
                     /tool="antismash"
                     /translation="TVLVTGASGALGGAVAHHLVTTHGANSLLLLSRT"
     aSDomain        complement(2982..3488)
                     /ASF="catalytic triad H,G,P inconclusive"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS35225_PKS_DH.1"
                     /evalue="1.00E-55"
                     /label="APK71_RS35225_PKS_DH.1"
                     /locus_tag="APK71_RS35225"
                     /protein_end="1154"
                     /protein_start="985"
                     /score="180.6"
                     /tool="antismash"
                     /translation="HPLLGALTVLADEGGAVLTGRLSTTTRGWLAEHRVHGAAVLPGTA
                     FVDLALWAGEQVGHPHLDELTLLAPLPVPAGDGIRIQVVVGAADDAGARSFGVYSRADD
                     APGQESGTPEWTHHAGGVLTGRREDHARLDPAPWPPSGARPVALDDLYPRLAAAGLDYG
                     PSFHGL"
     CDS_motif       complement(3330..3404)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0009"
                     /evalue="1.10E-09"
                     /label="PKSI-DH_m2"
                     /locus_tag="APK71_RS35225"
                     /protein_end="1038"
                     /protein_start="1013"
                     /score="30.7"
                     /tool="antismash"
                     /translation="WLAEHRVHGAAVLPGTAFVDLALWA"
     aSDomain        complement(3753..4613)
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS35225_PKS_AT.1"
                     /evalue="3.00E-109"
                     /label="APK71_RS35225_PKS_AT.1"
                     /locus_tag="APK71_RS35225"
                     /protein_end="897"
                     /protein_start="610"
                     /score="356.9"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="LFTGQGSQRPGMGEELYAAFPAYAEALDTVCEAFDGLLGRPLREV
                     LTARPGTPEAALLDETEYTQAALFAVEVALFRLLESWSLLPDFVAGHSIGELAAAHVAG
                     VFSLADACTLVAARGRLMQALPAGGAMVAVRATEEETATLLHGRTDVAVAAVNGPRSVV
                     ISGAEEAVLEVAALLEERGSSTRRLRVSHAFHSPLMDAMTADFRKVADSVEYRAPHIPL
                     VSTLTGRRATAAELCSADYWVRHARETVRHHDAVRSLADEEVTRFVELGPDGVLSAMAE
                     ETDTSG"
     CDS_motif       complement(3861..3893)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0008"
                     /evalue="2.70E-03"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="APK71_RS35225"
                     /protein_end="861"
                     /protein_start="850"
                     /score="11.3"
                     /tool="antismash"
                     /translation="YWVRHARETVR"
     CDS_motif       complement(4116..4154)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0007"
                     /evalue="1.80E-04"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="APK71_RS35225"
                     /protein_end="776"
                     /protein_start="763"
                     /score="14.7"
                     /tool="antismash"
                     /translation="AAVNGPRSVVISG"
     CDS_motif       complement(4245..4358)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0006"
                     /evalue="1.40E-21"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="APK71_RS35225"
                     /protein_end="733"
                     /protein_start="695"
                     /score="68.7"
                     /tool="antismash"
                     /translation="PDFVAGHSIGELAAAHVAGVFSLADACTLVAARGRLMQ"
     CDS_motif       complement(4563..4610)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0005"
                     /evalue="6.80E-06"
                     /label="PKSI-AT-M_m1"
                     /locus_tag="APK71_RS35225"
                     /protein_end="627"
                     /protein_start="611"
                     /score="18.5"
                     /tool="antismash"
                     /translation="FTGQGSQRPGMGEELY"
     aSDomain        complement(4983..6266)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS35225_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="2.10E-172"
                     /label="APK71_RS35225_PKS_KS.1"
                     /locus_tag="APK71_RS35225"
                     /protein_end="487"
                     /protein_start="59"
                     /score="565.8"
                     /tool="antismash"
                     /translation="VAIVAMSCRYPGGVRSPEDLWRLVADGTDAIGPAPTDRGWDLGAL
                     LDTDPDGTGTGFTGEGGFVHDAGAFDAGLFGMSPREALATDPQQRILLELAWETFERAG
                     LAPDALRGRDVGVFVGTGGQDYYDDLDADAVSDVVDGYLSTGTSAAVLSGRLSYTFGLE
                     GPALSVDTACSSSLVATHLAAQALRRKECSLALAGGAMVMSTPTPFVAFGKQRGLAPDG
                     RCKPFAEQADGTGWSEGAGLLLLERLSDARRNGHRVLAIIRGSAVNQDGASNGLSAPSG
                     PAQQRVIRQALAAAGLSASEVDAVEAHGTGTTLGDPIEAHALLATYGQDRPADRPLWLG
                     SIKSNIGHAQSAAGVSGIIKMVQALRHDTLPRTLHAAEPSSHIDWSAGRVRLLDEARPW
                     PRSATPRRAGVSSFGISGTNVHLILEEAP"
     CDS_motif       complement(5205..5249)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0004"
                     /evalue="3.30E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="APK71_RS35225"
                     /protein_end="413"
                     /protein_start="398"
                     /score="10.2"
                     /tool="antismash"
                     /translation="GSIKSNIGHAQSAAG"
     CDS_motif       complement(5310..5354)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0003"
                     /evalue="6.10E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="APK71_RS35225"
                     /protein_end="378"
                     /protein_start="363"
                     /score="12.1"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       complement(5730..5777)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0002"
                     /evalue="2.60E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="APK71_RS35225"
                     /protein_end="238"
                     /protein_start="222"
                     /score="19.4"
                     /tool="antismash"
                     /translation="GPALSVDTACSSSLVA"
     CDS_motif       complement(5985..6011)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35225_0001"
                     /evalue="5.30E-02"
                     /label="PKSI-KS_m2"
                     /locus_tag="APK71_RS35225"
                     /protein_end="153"
                     /protein_start="144"
                     /score="6.8"
                     /tool="antismash"
                     /translation="DPQQRILLE"
     aSDomain        complement(6288..6359)
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS35225_PKS_Docking_Nterm.
                     1"
                     /evalue="1.80E-13"
                     /label="APK71_RS35225_PKS_Docking_Nterm.1"
                     /locus_tag="APK71_RS35225"
                     /protein_end="52"
                     /protein_start="28"
                     /score="41.8"
                     /tool="antismash"
                     /translation="DRLLGYLKRVTAELHQTRQRLHEA"
     gene            complement(6443..11395)
                     /locus_tag="APK71_RS39325"
     CDS             complement(6443..11395)
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (3-31). E-value:
                     1e-13. Score: 42.6. Matches aSDomain:
                     nrpspksdomains_APK71_RS39325_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (35-447). E-value:
                     6.2e-169. Score: 554.3. Matches aSDomain:
                     nrpspksdomains_APK71_RS39325_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (558-864). E-value: 1e-104.
                     Score: 342.1. Matches aSDomain:
                     nrpspksdomains_APK71_RS39325_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_KR (1203-1382). E-value: 7.2e-58.
                     Score: 187.5. Matches aSDomain:
                     nrpspksdomains_APK71_RS39325_PKS_KR.1"
                     /NRPS_PKS="Domain: ACP (1491-1564). E-value: 6.4e-31.
                     Score: 98.5. Matches aSDomain:
                     nrpspksdomains_APK71_RS39325_ACP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (1575-1648). E-value:
                     1.4e-20. Score: 65.9. Matches aSDomain:
                     nrpspksdomains_APK71_RS39325_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1093: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082179.1"
                     /locus_tag="APK71_RS39325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_055470053.1"
                     /sec_met_domain="mod_KS (E-value: 5.3e-214, bitscore:
                     698.4, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 1.3e-84, bitscore:
                     271.4, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 5e-106, bitscore: 342.1,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 6.3e-59, bitscore:
                     186.6, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 2.3e-13, bitscore:
                     38.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGEERLRDYLKRATADLRHTKQRLRDVEARAHEPVAVVAMGCRY
                     PGDVQTPEDLWRLVADGTDAISGFPVDRGWDTEGIYDPTPGRPGKTYVRHGGFLHDAAE
                     FDAAFFGISPREALRADPQERLLLEVAWETIERAGIDPGSLKGTATGVFAGLMYHDYAG
                     GSPGGAFASGHIAYTLGLEGPAYTVDTACSSSLVALHLACQSLRKGESDLALAGGAAVM
                     GTPEMFVDFSRQRGLAPDGRAKSFAEAADGTNWSEGVGLLLLERLSDAVRNGHPVLAVV
                     RGSAVSQDGASNGISAPNGPAQQRVIRLALADAGLDTADVDAVEAHGTGTTLGDPIEAQ
                     ALIATYGQGRTEDRPLWLGSVKSNIGHPQAAAGAAAVIKMVMATRHGILPKTLHVDEPT
                     RHVDWSAGQVRLLTEPVHWPDTGRPRRSAVSSFGISGTNVHVVIEQAPQDAHPRTPDDR
                     VPDDGASAGTAVAWPLSAKTPDALTAQADRLATYLEENPGRSPAGVARTLATGRSPFAH
                     RAVVVGGDRDELVAGLRALAAGTPPASVPTGRADVRGRTVFVFPGQGSQWTGMATELLA
                     GAPAFAQRFADCEKALAPYLDWSPGEVLRGAPDSPAMDRVDVVQPLLWAVMVSLAALWQ
                     EYGVHPDAVVGHSQGEIAAACVSGALSLEDGARVVALRSRAIARGLAGPGGMASVALPA
                     AELRARLARRPDELSVAAVNGARSTAVSGDADALDALLDELRAEKVRARRIPVDYASHS
                     AQVARIEEQLLRDLAPLTPGRGTVPMLSTVTGEFVADGQLDAAYWYANLRHTVEFASAV
                     DRLAAQGHTTYIEVSPHPVLTMSVQETLDAVADRAQAATPADTVVVGTLRRDEGGLPRM
                     LTALGELHVRGVPQRWPDLHPQAEPADLPTYAFQRRRYWAQAPDTDRASAATPDTAPDA
                     AFWNEVESGDADSLARLIGADAAPLRDVVPALAAWRRARLDAATVDSWRYRMTWQPVTA
                     PADATPSGTWLAVVPAPPADDSGPHTGLPRTVLDGLRAHGPRLVTVEVPDDADRAGLAE
                     RIRAALPGEPPDRVVSLLSLDTRTHPAHPALARATTATVTLVQALADLGHTAPLWCLTS
                     GAVAVDSHDEPPVPERAAVWGLGTVLALDHPLTWGGIADLPAGADVRTVRLLCSRLDAP
                     GTRGEDQLAFRPSGVYARRLTRAPLGDREPVRAWRPRGTVLVTGGTGAIGGHVARWLAR
                     SGAAHVVLAGRRGRTADGIAGLEAELVALGTEVTVAACDAADRDDLARLLDGLPADQPL
                     TAVVHAAGVLGEGKPVTETTLEEFAAITRAKTAGAEHLDALLADRPLDAFVLFSSGAAV
                     WGTAGQTAYASANAHLDALAQRRRARGLTATSVAWGPWGGGGMVGDDAAGHLRSLGLPQ
                     LPPSLAIEALQKALDHDESGLVVADIDWGRFLPVYTLARRRPLLDALPELQTLPDPAAA
                     TPADDPDGTNGRDLAAELADLTPPERYRSLLALVRRQVAALLGFDGPAAVDARLAFKEL
                     GFESVTAVDLRNRLGAATGLRLPATLVFDHSTPQALAQHLCDELVGHAPATEPEEPVLA
                     QVARLEAAVAALPPDDTSRAGLTARLRALLNTLDHTVPGPRGTPDVEVAEQLHTATVDD
                     VFAFIDREFGGS"
     aSDomain        complement(6452..6670)
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS39325_PKS_Docking_Cterm.
                     1"
                     /evalue="1.40E-20"
                     /label="APK71_RS39325_PKS_Docking_Cterm.1"
                     /locus_tag="APK71_RS39325"
                     /protein_end="1648"
                     /protein_start="1575"
                     /score="65.9"
                     /tool="antismash"
                     /translation="PVLAQVARLEAAVAALPPDDTSRAGLTARLRALLNTLDHTVPGPR
                     GTPDVEVAEQLHTATVDDVFAFIDREFG"
     aSDomain        complement(6704..6922)
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS39325_ACP.1"
                     /evalue="6.40E-31"
                     /label="APK71_RS39325_ACP.1"
                     /locus_tag="APK71_RS39325"
                     /protein_end="1564"
                     /protein_start="1491"
                     /score="98.5"
                     /tool="antismash"
                     /translation="LALVRRQVAALLGFDGPAAVDARLAFKELGFESVTAVDLRNRLGA
                     ATGLRLPATLVFDHSTPQALAQHLCDEL"
     aSModule        complement(6704..11290)
                     /complete
                     /domains="nrpspksdomains_APK71_RS39325_PKS_KS.1"
                     /domains="nrpspksdomains_APK71_RS39325_PKS_AT.1"
                     /domains="nrpspksdomains_APK71_RS39325_PKS_KR.1"
                     /domains="nrpspksdomains_APK71_RS39325_ACP.1"
                     /locus_tags="APK71_RS39325"
                     /monomer_pairings="mmal -> Me-ohmal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(7250..7786)
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS39325_PKS_KR.1"
                     /evalue="7.20E-58"
                     /label="APK71_RS39325_PKS_KR.1"
                     /locus_tag="APK71_RS39325"
                     /protein_end="1382"
                     /protein_start="1203"
                     /score="187.5"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTVLVTGGTGAIGGHVARWLARSGAAHVVLAGRRGRTADGIAGLE
                     AELVALGTEVTVAACDAADRDDLARLLDGLPADQPLTAVVHAAGVLGEGKPVTETTLEE
                     FAAITRAKTAGAEHLDALLADRPLDAFVLFSSGAAVWGTAGQTAYASANAHLDALAQRR
                     RARGLTATSVAWGPWG"
     CDS_motif       complement(7295..7405)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS39325_0011"
                     /evalue="1.10E-17"
                     /label="PKSI-KR_m4"
                     /locus_tag="APK71_RS39325"
                     /protein_end="1367"
                     /protein_start="1330"
                     /score="56.6"
                     /tool="antismash"
                     /translation="LDAFVLFSSGAAVWGTAGQTAYASANAHLDALAQRRR"
     CDS_motif       complement(7685..7783)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS39325_0010"
                     /evalue="4.70E-13"
                     /label="PKSI-KR_m1"
                     /locus_tag="APK71_RS39325"
                     /protein_end="1237"
                     /protein_start="1204"
                     /score="41.7"
                     /tool="antismash"
                     /translation="TVLVTGGTGAIGGHVARWLARSGAAHVVLAGRR"
     aSDomain        complement(8804..9721)
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS39325_PKS_AT.1"
                     /evalue="1.00E-104"
                     /label="APK71_RS39325_PKS_AT.1"
                     /locus_tag="APK71_RS39325"
                     /protein_end="864"
                     /protein_start="558"
                     /score="342.1"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGSQWTGMATELLAGAPAFAQRFADCEKALAPYLDWSPGEV
                     LRGAPDSPAMDRVDVVQPLLWAVMVSLAALWQEYGVHPDAVVGHSQGEIAAACVSGALS
                     LEDGARVVALRSRAIARGLAGPGGMASVALPAAELRARLARRPDELSVAAVNGARSTAV
                     SGDADALDALLDELRAEKVRARRIPVDYASHSAQVARIEEQLLRDLAPLTPGRGTVPML
                     STVTGEFVADGQLDAAYWYANLRHTVEFASAVDRLAAQGHTTYIEVSPHPVLTMSVQET
                     LDAVADRAQAATPADTVVVGTLRRD"
     CDS_motif       complement(8900..8929)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS39325_0009"
                     /evalue="9.70E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="APK71_RS39325"
                     /protein_end="832"
                     /protein_start="822"
                     /score="8.8"
                     /tool="antismash"
                     /translation="YIEVSPHPVL"
     CDS_motif       complement(8972..9019)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS39325_0008"
                     /evalue="2.10E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="APK71_RS39325"
                     /protein_end="808"
                     /protein_start="792"
                     /score="16.5"
                     /tool="antismash"
                     /translation="LDAAYWYANLRHTVEF"
     CDS_motif       complement(9128..9157)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS39325_0007"
                     /evalue="2.50E-03"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="APK71_RS39325"
                     /protein_end="756"
                     /protein_start="746"
                     /score="10.7"
                     /tool="antismash"
                     /translation="VDYASHSAQV"
     CDS_motif       complement(9374..9484)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS39325_0006"
                     /evalue="3.60E-19"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="APK71_RS39325"
                     /protein_end="674"
                     /protein_start="637"
                     /score="60.5"
                     /tool="antismash"
                     /translation="GVHPDAVVGHSQGEIAAACVSGALSLEDGARVVALRS"
     CDS_motif       complement(9491..9556)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS39325_0005"
                     /evalue="1.90E-09"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="APK71_RS39325"
                     /protein_end="635"
                     /protein_start="613"
                     /score="29.7"
                     /tool="antismash"
                     /translation="DRVDVVQPLLWAVMVSLAALWQ"
     CDS_motif       complement(9671..9727)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS39325_0004"
                     /evalue="9.10E-10"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="APK71_RS39325"
                     /protein_end="575"
                     /protein_start="556"
                     /score="30.1"
                     /tool="antismash"
                     /translation="VFVFPGQGSQWTGMATELL"
     aSDomain        complement(10055..11290)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS39325_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="6.20E-169"
                     /label="APK71_RS39325_PKS_KS.1"
                     /locus_tag="APK71_RS39325"
                     /protein_end="447"
                     /protein_start="35"
                     /score="554.3"
                     /tool="antismash"
                     /translation="VAVVAMGCRYPGDVQTPEDLWRLVADGTDAISGFPVDRGWDTEGI
                     YDPTPGRPGKTYVRHGGFLHDAAEFDAAFFGISPREALRADPQERLLLEVAWETIERAG
                     IDPGSLKGTATGVFAGLMYHDYAGGSPGGAFASGHIAYTLGLEGPAYTVDTACSSSLVA
                     LHLACQSLRKGESDLALAGGAAVMGTPEMFVDFSRQRGLAPDGRAKSFAEAADGTNWSE
                     GVGLLLLERLSDAVRNGHPVLAVVRGSAVSQDGASNGISAPNGPAQQRVIRLALADAGL
                     DTADVDAVEAHGTGTTLGDPIEAQALIATYGQGRTEDRPLWLGSVKSNIGHPQAAAGAA
                     AVIKMVMATRHGILPKTLHVDEPTRHVDWSAGQVRLLTEPVHWPDTGRPRRSAVSSFGI
                     SGTNVHVVIEQAP"
     CDS_motif       complement(10277..10321)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS39325_0003"
                     /evalue="2.60E-03"
                     /label="PKSI-KS_m6"
                     /locus_tag="APK71_RS39325"
                     /protein_end="373"
                     /protein_start="358"
                     /score="10.5"
                     /tool="antismash"
                     /translation="GSVKSNIGHPQAAAG"
     CDS_motif       complement(10382..10426)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS39325_0002"
                     /evalue="4.40E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="APK71_RS39325"
                     /protein_end="338"
                     /protein_start="323"
                     /score="12.5"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       complement(10802..10849)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS39325_0001"
                     /evalue="5.90E-07"
                     /label="PKSI-KS_m3"
                     /locus_tag="APK71_RS39325"
                     /protein_end="198"
                     /protein_start="182"
                     /score="21.3"
                     /tool="antismash"
                     /translation="GPAYTVDTACSSSLVA"
     aSDomain        complement(11303..11386)
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS39325_PKS_Docking_Nterm.
                     1"
                     /evalue="1.00E-13"
                     /label="APK71_RS39325_PKS_Docking_Nterm.1"
                     /locus_tag="APK71_RS39325"
                     /protein_end="31"
                     /protein_start="3"
                     /score="42.6"
                     /tool="antismash"
                     /translation="EERLRDYLKRATADLRHTKQRLRDVEAR"
     gene            complement(11392..15507)
                     /locus_tag="APK71_RS35235"
     CDS             complement(11392..15507)
                     /NRPS_PKS="Domain: PKS_AT (0-300). E-value: 1.2e-82. Score:
                     269.5. Matches aSDomain:
                     nrpspksdomains_APK71_RS35235_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (367-534). E-value: 1.6e-60.
                     Score: 196.2. Matches aSDomain:
                     nrpspksdomains_APK71_RS35235_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (886-1067). E-value: 1.6e-56.
                     Score: 183.1. Matches aSDomain:
                     nrpspksdomains_APK71_RS35235_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1160-1246). E-value: 1.5e-31.
                     Score: 100.6. Matches aSDomain:
                     nrpspksdomains_APK71_RS35235_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (1256-1340). E-value:
                     1.4e-09. Score: 30.7. Matches aSDomain:
                     nrpspksdomains_APK71_RS35235_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012901.4"
                     /locus_tag="APK71_RS35235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type I polyketide synthase"
                     /protein_id="WP_079080752.1"
                     /sec_met_domain="PKS_AT (E-value: 6.2e-84, bitscore: 269.5,
                     seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short (E-value: 1.4e-62, bitscore:
                     198.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.3e-14, bitscore:
                     42.3, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFPGQGSGWVGMGRGLYGVFPVFAEAFDGVCGLLEGELGGVLPVG
                     VGLRDVVFGEVELGSGVGTGVAQAGLFAVGVGLVGLLGSWGVRPDWVVGHSVGEVCAAW
                     VAGVLSLEDACVLVGARGRLMEGVGAGGVMVAVEASEGEVVPLLGGGVWLGAVNGPRSV
                     VLSGVRGAVEEAVAGFVGLGRRVRWLEVADAFHSGLMDGVLEEFRGVVEGLELGDPVGV
                     GVVSSVSGGVVGAGVMSSPGYWVEQISSAVRFADAVGVVEAAGVVSFVEVGPGSVLSGM
                     VADSVAEGSPAVGVPLLRKGRDEVLSLVEGVGRLHERGVTVDWEAFFAGQGAERIDLPT
                     YAFQRRLYWLTPEAPSQVEAAGLVSPGHPLLGAAVVAPETGGITLTGRLALGTAPWLAD
                     HQVLGNVVLPGTAFVELAIQAGDRLGLPVLEELTLAAPLTLATDTAVALQVVVGERDES
                     GRRPVTVYSRTEGVPDDAPWDRHATGVLTSEDDGTGTESGELTVWPPEKAASVDIDGAY
                     ERLAALGYDYGPVFAGLRAVWHRGEELFAEVSLPEDGPAGTDAFALHPALLDAALHAQL
                     LGTGTDTADTGTGTGRTLLPFAWNGVTLHAVGATSLRVRIAPTGADNGAVSVTLADADG
                     EPVASVRSLAVRPVSPEQLGTGRGTAAGESLFRLDWSVAATTDEPADTAGWVTVGRADV
                     PVGALLGGGGETARHDDGLAALLADLAAGAPAPEVLIVAADDGTPTPHTSASCPPGMPT
                     GAPADVRARTLGVLARLRSWLADERLAATRLVVLTRNAVEAGDTTVDPAEAAVWGLVRA
                     AQAEHPGRIVIADIDHDIADIDHDEASRRSLTAAIASGEPELALRAGKTLVPRLVPAAA
                     PAPPAPPASGAWDPSGTVLITGGTGGLGALLARHLVGEHGVRHLVLAGRRGIEAAGARD
                     LVAELTALAPVDVRVAACDVADREALAALLDSIPAAHPLTAVVHAAGVVDNALVGSLTD
                     EQVETVLRPKADGAHHLHELTAGRDLSAFVLFSSAAGYLIGAGQGGYAAANTFLDGLAQ
                     HRRAQGLPALSLAWGLWAESDGMAARLDRAGRERLDRLGLPPLATADALALFDAALAAD
                     AATLVPVRLDVPVLRARGGQLPPVLRGFARGPAVRRSAGTAGRAQEGPDLAERLSGLSP
                     AEQDRTLTELVGRHVAEVLGYGSADAMEPGRSFTDLGFDSLAAVELRNALATATGLKLP
                     ATLVFDHPDAEALVRHLRAELVSAPLGPVEAVLAEADQLEAALLALSAQNGAPGGDGTS
                     GPAADPAALARITARLEALQRKWHTVQGPEPEHEAEQDLDIVTDDELFAALDRELGPHA
                     DGPSDVADRTRSAPETGPGTASERGDRR"
     aSDomain        complement(11488..11739)
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS35235_PKS_Docking_Cterm.
                     1"
                     /evalue="1.40E-09"
                     /label="APK71_RS35235_PKS_Docking_Cterm.1"
                     /locus_tag="APK71_RS35235"
                     /protein_end="1340"
                     /protein_start="1256"
                     /score="30.7"
                     /tool="antismash"
                     /translation="VLAEADQLEAALLALSAQNGAPGGDGTSGPAADPAALARITARLE
                     ALQRKWHTVQGPEPEHEAEQDLDIVTDDELFAALDRELG"
     aSDomain        complement(11770..12027)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS35235_PKS_PP.1"
                     /evalue="1.50E-31"
                     /label="APK71_RS35235_PKS_PP.1"
                     /locus_tag="APK71_RS35235"
                     /protein_end="1246"
                     /protein_start="1160"
                     /score="100.6"
                     /tool="antismash"
                     /translation="LSGLSPAEQDRTLTELVGRHVAEVLGYGSADAMEPGRSFTDLGFD
                     SLAAVELRNALATATGLKLPATLVFDHPDAEALVRHLRAEL"
     aSModule        complement(11770..15507)
                     /complete
                     /domains="nrpspksdomains_APK71_RS35235_PKS_AT.1"
                     /domains="nrpspksdomains_APK71_RS35235_PKS_DH.1"
                     /domains="nrpspksdomains_APK71_RS35235_PKS_KR.1"
                     /domains="nrpspksdomains_APK71_RS35235_PKS_PP.1"
                     /locus_tags="APK71_RS35235"
                     /monomer_pairings="mal -> ccmal"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(12307..12849)
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS35235_PKS_KR.1"
                     /evalue="1.60E-56"
                     /label="APK71_RS35235_PKS_KR.1"
                     /locus_tag="APK71_RS35235"
                     /protein_end="1067"
                     /protein_start="886"
                     /score="183.1"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTVLITGGTGGLGALLARHLVGEHGVRHLVLAGRRGIEAAGARDL
                     VAELTALAPVDVRVAACDVADREALAALLDSIPAAHPLTAVVHAAGVVDNALVGSLTDE
                     QVETVLRPKADGAHHLHELTAGRDLSAFVLFSSAAGYLIGAGQGGYAAANTFLDGLAQH
                     RRAQGLPALSLAWGLWAE"
     CDS_motif       complement(12355..12459)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35235_0006"
                     /evalue="2.30E-16"
                     /label="PKSI-KR_m4"
                     /locus_tag="APK71_RS35235"
                     /protein_end="1051"
                     /protein_start="1016"
                     /score="52.3"
                     /tool="antismash"
                     /translation="AFVLFSSAAGYLIGAGQGGYAAANTFLDGLAQHRR"
     CDS_motif       complement(12745..12846)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35235_0005"
                     /evalue="1.10E-10"
                     /label="PKSI-KR_m1"
                     /locus_tag="APK71_RS35235"
                     /protein_end="921"
                     /protein_start="887"
                     /score="34.1"
                     /tool="antismash"
                     /translation="TVLITGGTGGLGALLARHLVGEHGVRHLVLAGRR"
     aSDomain        complement(13906..14406)
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS35235_PKS_DH.1"
                     /evalue="1.60E-60"
                     /label="APK71_RS35235_PKS_DH.1"
                     /locus_tag="APK71_RS35235"
                     /protein_end="534"
                     /protein_start="367"
                     /score="196.2"
                     /tool="antismash"
                     /translation="HPLLGAAVVAPETGGITLTGRLALGTAPWLADHQVLGNVVLPGTA
                     FVELAIQAGDRLGLPVLEELTLAAPLTLATDTAVALQVVVGERDESGRRPVTVYSRTEG
                     VPDDAPWDRHATGVLTSEDDGTGTESGELTVWPPEKAASVDIDGAYERLAALGYDYGPV
                     FAGL"
     CDS_motif       complement(14245..14322)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35235_0004"
                     /evalue="9.60E-12"
                     /label="PKSI-DH_m2"
                     /locus_tag="APK71_RS35235"
                     /protein_end="421"
                     /protein_start="395"
                     /score="37.3"
                     /tool="antismash"
                     /translation="WLADHQVLGNVVLPGTAFVELAIQAG"
     aSDomain        complement(14608..15507)
                     /ASF="Neither malonyl-CoA or methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS35235_PKS_AT.1"
                     /evalue="1.20E-82"
                     /label="APK71_RS35235_PKS_AT.1"
                     /locus_tag="APK71_RS35235"
                     /protein_end="300"
                     /protein_start="0"
                     /score="269.5"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="MFPGQGSGWVGMGRGLYGVFPVFAEAFDGVCGLLEGELGGVLPVG
                     VGLRDVVFGEVELGSGVGTGVAQAGLFAVGVGLVGLLGSWGVRPDWVVGHSVGEVCAAW
                     VAGVLSLEDACVLVGARGRLMEGVGAGGVMVAVEASEGEVVPLLGGGVWLGAVNGPRSV
                     VLSGVRGAVEEAVAGFVGLGRRVRWLEVADAFHSGLMDGVLEEFRGVVEGLELGDPVGV
                     GVVSSVSGGVVGAGVMSSPGYWVEQISSAVRFADAVGVVEAAGVVSFVEVGPGSVLSGM
                     VADSVAEGSPAVGVPLLRK"
     CDS_motif       complement(15007..15042)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35235_0003"
                     /evalue="2.00E-03"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="APK71_RS35235"
                     /protein_end="167"
                     /protein_start="155"
                     /score="11.5"
                     /tool="antismash"
                     /translation="AVNGPRSVVLSG"
     CDS_motif       complement(15130..15252)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35235_0002"
                     /evalue="5.00E-21"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="APK71_RS35235"
                     /protein_end="126"
                     /protein_start="85"
                     /score="66.9"
                     /tool="antismash"
                     /translation="GVRPDWVVGHSVGEVCAAWVAGVLSLEDACVLVGARGRLME"
     CDS_motif       complement(15457..15507)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS35235_0001"
                     /evalue="1.40E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="APK71_RS35235"
                     /protein_end="17"
                     /protein_start="0"
                     /score="17.5"
                     /tool="antismash"
                     /translation="MFPGQGSGWVGMGRGLY"
ORIGIN
        1 ccctgcccat acgccgcaat cagcgcctga gcctcgatcg gatcccccag caccgtcccc
       61 gtcccgtgcg cctccaccac atccacatcc accgccgaca cacccgcatc cgccaacgcc
      121 gcacgaatca cccgctgctg cgacggacca ttcggcgccg tcaacccatt cgacgcacca
      181 tcctgattca ccgcagaacc agccaccacc gccaacacct catgacccaa ccgccgcgca
      241 tccgacaacc gctccaccac caacacaccc acaccctcgg accaccccgt cccccccgca
      301 cccgcaccaa acgaccgaca ccgcccatcc accgacaacc cccgctgccg cgaaaactcc
      361 acaaacgtct ccggcgtcgc catcaccgtc accccacccg ccaacgccag cgaacactca
      421 ccccgccgca acgactgcac cgccaaatgc aaccccacca acgacgacga acacgccgta
      481 tccacactca ccgccggccc ctccaacccc aacgcatacg ccacccgccc cgagacgacc
      541 gcgccggtgc tgttgctgcc cacgtagtcg tggtactgga cgccggcgaa gacgcccgtc
      601 ccgctccccc gcaacgaacc cggaacaatc cccgcccgct ccaacgcctc ccacgacgac
      661 tccagcaaca accgctgctg cggatccatc gtcagggcct cgttcggact gatgccgaag
      721 aagtcggcgt cgaagtcggc cgcgtccttc aggaatccgc cgtggcgtac gtaggtcgac
      781 ccgggacgca cgccctcggg gtcgtacaag ccgtcgatgt cccagccgcg gtcctcgggg
      841 aactccccga tggcgtccgt gccttcggag accagccgcc acaggccctc gggcgagtcg
      901 accccgccgg ggaagcggca gcccatgccg acgatcgcga tgggctcgtc atgggtggcc
      961 ggggacgagg gcaccgagga gaccggtccc tcggcggtcc cgacgagttc ctcctgcagg
     1021 tgacggacga gagccgtgac ggtcggatgg tcgaagacga gagtggcggg cagccggaca
     1081 ccggtggcgg tcgcgaggcc gttgcgcagt tccacggccg tcaaggagtc gaagcccagt
     1141 tcgtggaagc cgcggtcggg ctcgacggcc agcggggagt cgtgaccgag gaccgccgcc
     1201 acgtgaccgc ggaccaggtc gaggagcatg gtgtgctgtt cggactcggg caggccgcgc
     1261 agccgatccg cgtacggcac gcccggtgtc gaaccggtcg aggcggtccc gcccttcacc
     1321 gggcggcgcg cgtcgcgggc cgcggggccg cggagatgcg cggcgccgag gccggcgggt
     1381 atcaccgtgg gttccgtcgc gcggagcgcg gcgtcgaaga ggcccaggcc ctcggcagcg
     1441 gacagcgggc gcacgccgct gcgcgtcatc cgggcgcgat aggtgtcgcc gagccccgcg
     1501 gtcattccgt gcacggccgt cgtgccgtcg tcctccccga ccggtgccgt gtcggcgagc
     1561 caggggcccc aggcgagcga gagcgcgggc cggccctggg tgcggcggcg cgcggcgagg
     1621 gcgtccagga acgtgttcgc ggccgcgtag ttggcctgcc cgggagcgcc gaggatgccg
     1681 gagacggagg agaacagcac gaaggcggtg aggtccgcgt cgcgggtcag ctcgtccagg
     1741 tgcagggcgc cggccacctt cggcggcagt acggtgtcga cccgttccgg ggtcagggac
     1801 gacacgacgc cgtcgtccag cacgcccgcg gcgtggacga ctccggtcag gggccggtcg
     1861 gcgggcacgg tcgcgagggc ggcggcgagc tggtcgcggt cggcgacgtc gcaggcggcg
     1921 gtggtcacca cggcgccgag ttcgcgcagt cgcgtcgcca gcgcggccag ccgggggtcc
     1981 gcctcgccgg tgcggctgag caggagcagg ctgtttgcgc cgtgcgtggt caccaggtgg
     2041 tgggcgaccg cgccgccgag ggcgccggaa gcgccggtga ccaggacggt gccgtggggc
     2101 gggaacgcgg cgccggcgtc ctcggatccg gtgctcacgc ggctgagccg cgcgacgtgc
     2161 agtgtgccct cgcgaacggc ggcctgcggt tcgccggagt ccagcagcgc ggggaggaac
     2221 gcggcggcgt ccgcggcatc ggtgccgctt tccaggtcca gcaggaccag ccggccgggg
     2281 tgttcggtct gggcggagcg caccaggccg tgcacggccg caccggccag gtcgatctcc
     2341 gtcgccgcgt cgcccgccgt cgcgccggtg gtcaccacga cgagccgggg ctggtcctcg
     2401 gagggcgcgt tcaggtgttc ctgcagagcg gcgagggtct tgtgcagggt cgcgcggacg
     2461 gcctcgaagg tgtcctgtcc gtccgccggc gggccgcccg cgggcaggat ccgtaccgtg
     2521 tggtccagcc cgtcggcgga cgcggccgtg tcacgccccg cgcggtcctg tcccgcggcg
     2581 gggacccagt ccatgcggaa gaccggcagc cgctcgtcgg ttccggccgc ccggaaggtg
     2641 acggagtcga tccgggccac cggggatccg gtgctgtccg cgatgtcggc cgtgtaggcg
     2701 tcggcggtgg tcggcgtgaa ccgcacccgc agcatcgagg cgccccggga gtacagcgag
     2761 acgccggacc aggtgaaggg cagccgcccg ggtgcggagg cgcccgtcgg ggtgcccgcg
     2821 gaaccggaag aggtggcgtc ggtcccgagg gaggcggcga gcgcgtgggt cgcggcgtcg
     2881 agcaccgccg gatgcagggc gtgccgggca ctgtcgtggc cggcctccgc gggcagtgcc
     2941 acctcggcga ggacgtcctc cccgtgctgc cagaccgccc gcaggccgtg gaaggacgga
     3001 ccgtagtcca ggcccgcggc cgccagccgg ggatacaggt cgtcgagggc taccggccgc
     3061 gcgccggagg gcggccacgg tgccgggtcg agtcgggcgt ggtcctcgcg acggccggtg
     3121 agcacaccgc cggcgtggtg ggtccactcc ggggtgccgg actcctggcc cggggcgtcg
     3181 tccgcgcggg agtagacgcc gaacgaccgg gcgcccgcgt cgtcggcggc gcccacgacg
     3241 acctggatgc gtatgccgtc accggccggc accggcaggg gggcgagcag tgtcagctcg
     3301 tcgaggtggg ggtggcccac ctgctcgccg gcccacagcg ccaggtccac gaaggccgtc
     3361 cccgggagca ccgcggcgcc gtggacccgg tgctcggcca gccagccgcg tgtcgtggtg
     3421 gacaggcgtc cggtcagtac cgctccgccc tcgtccgcga gcacggtgag cgccccgagc
     3481 agcggatggt cggcggggtc gagcccgacc gctgccgggc cccggcccgc ggcccgctcg
     3541 tccagccagt agcggcggtg ccggaaggcg taggtgggca gatcggtccg gcgggcaccg
     3601 agaccggcga acaccgcctc ccagtcgggc gcgaggccgc tgacgtacat ccgcgcgagc
     3661 gcgctcagga gggtggcggt cccgggccgt ccggcgcgca gcagcgggac ccggagcacg
     3721 gcaggaccgg cggcgggggc gtcgtgcgcg ggcccgctcg tgtcggtctc ttccgccatg
     3781 gcgctgagga cgccgtcggg gcccagctcg acgaacctgg tgacctcctc gtcggcgagg
     3841 ctgcgcacgg cgtcgtggtg gcgcacggtc tcgcgggcgt ggcggaccca gtagtcggcg
     3901 gagcacagtt cggcggccgt ggcccggcgg ccggtcagtg tcgatacgag cggaatgtgc
     3961 ggcgcccggt actccaccga gtccgcgacc ttgcggaagt cggccgtcat cgcgtccatc
     4021 agcggcgagt ggaaggcgtg cgagacccgc agccgccggg tgctgctgcc gcgctcctcc
     4081 aggagtgcgg ccacctccag gaccgcttcc tcggcgccgg agatcaccac ggaccggggc
     4141 ccgttgacgg cggcgaccgc gacgtccgtc ctgccgtgca gcagtgtggc ggtctcctcc
     4201 tcggtggccc ggaccgccac catggctccg cccgcgggca gcgcctgcat gagccggcct
     4261 cgggcggcca ccagggtgca ggcgtcggcg agcgagaaca ctccggcgac gtgcgcggcc
     4321 gccagttcgc cgatcgagtg accggccacg aagtccggca gcagggacca cgattccagc
     4381 agccggaaga gcgcgacctc cacggcgaac agcgcggcct gggtgtactc ggtctcgtcg
     4441 aggagcgccg cctcgggggt cccggggcga gcggtcaata cctcgcgcag tggccgtccg
     4501 agcagtccgt cgaacgcctc gcacaccgtg tcgagggctt cggcgtacgc ggggaacgcg
     4561 gcgtacagct cctctcccat gccgggacgc tgggagccct ggccggtgaa gaggaaggcg
     4621 gtgagcccgt tcgtcgcggt gccgctgaag gtgttcgggg cgctctcgcc cgcggagagg
     4681 gccgcgaggc cgcgccgcgc cgtcgtgcgg tccgtggcga ggacgacggc acggtggtcg
     4741 agggatgcgc ggccggtcgc cagcgagtag gcggtgtcga cgagtgcggt gtcgacgtcc
     4801 ccgtcgtgcg tgccgtgctc ggcgtgttcg gcgtgttcgg cgtgttcgag cagccgtgcc
     4861 gcctgggcgc gcagtgcttc ggcgccgcgt ccggagacga ccagcggcac ggggacgccg
     4921 tccggtgcgc cggcccctcc ccggtccggg ccgtcgccgg tggcgggctc cgggtccggg
     4981 gcgggtgctt cttccaggat caggtggacg ttggtgccgc tgatcccgaa cgaggacacg
     5041 ccggcgcggc gcggtgtcgc ggaccggggc cacggccgcg cctcgtcgag gagccgcacc
     5101 cggcccgcgg accagtcgat gtgcgaggag ggctcggcgg cgtggagggt gcgcgggagg
     5161 gtgtcgtgcc gcagggcctg gaccatcttg atgatgccgc tgacaccggc ggccgactgg
     5221 gcgtgtccga tgttcgactt gatggagccg agccacagcg gacggtccgc gggccggtcc
     5281 tggccgtagg tggcgaggag ggcgtgcgcc tcgatggggt cgcccagcgt ggttccggtg
     5341 ccgtgtgcct ccacggcgtc cacttcggag gcggacagcc cggcggcggc cagggcctgg
     5401 cggatgaccc gctgctgggc ggggccgctg ggggccgaca gaccgttcga cgcgccgtcc
     5461 tggttgacgg cggagccgcg gatgatggcg agcacgcggt gtccgttgcg ccgggcgtcg
     5521 gagaggcgtt ccaggagcag gaggcccgcg ccctcggacc agccggtgcc gtcggcctgc
     5581 tcggcgaagg gcttgcagcg gccgtcgggg gccagaccgc gctgcttgcc gaacgcgacg
     5641 aacggcgtgg gcgtggacat caccatggcg ccgcccgcga gggcgagcga gcattccttg
     5701 cggcgcaggg cctgcgcggc gaggtgggtg gcgaccaggg aggaggagca ggcggtgtcg
     5761 acactgaggg cggggccctc gaggccgaac gtgtaggaca gccggcccga gagcacggcg
     5821 gccgaggtgc cggtgctgag gtatccgtcc acgacgtcgg agacggcgtc cgcgtcgagg
     5881 tcgtcgtagt agtcctggcc gccggtgccg acgaagacgc cgacgtcgcg tccgcgcagc
     5941 gcgtcggggg cgaggcccgc gcgttcgaag gtctcccagg ccagttcgag caggatccgc
     6001 tgttgcgggt cggtggccag ggcctcgcgc ggtgacatgc cgaacagtcc ggcgtcgaac
     6061 gcgccggcgt cgtggacgaa gccgccttcg ccggtgaagc cggtgccggt gccgtccggg
     6121 tcggtgtcga gcagggcacc gaggtcccag ccacggtccg tgggggcggg cccgatggcg
     6181 tcggtgccgt cggcgacgag gcgccacagg tcttcggggg agcgtacgcc gccggggtag
     6241 cggcagctca tggcgacgat ggcgacgggt tcccgctcgt cctcgcccgc ctcgtgcagc
     6301 cgctgccggg tctggtggag ttcggcggtg acccgcttga gatagccgag gagcctgtcc
     6361 tggtcggcct ggccggtccg gtccgcgccc tcgtcgcggg caccgtcggc cccgtgttcc
     6421 gtccggctgt cacggactcc catcaggatc ccccgaattc tctgtcgatg aaggcgaaga
     6481 cgtcgtccac ggttgccgtg tgaagctgtt cggcgacttc cacatccggt gtcccccgtg
     6541 gaccgggaac ggtgtggtcg agcgtgttca gcagggcgcg cagccgggcc gtgaggccgg
     6601 cgcgggaggt gtcgtccggc ggcagcgcgg ccaccgccgc ctccaggcgg gccacctgcg
     6661 ccaggaccgg ctcttcgggc tccgtcgccg gggcgtggcc gacgagttcg tcgcagaggt
     6721 gctgggcgag cgcctgcggt gtggagtggt cgaagacgag cgtggcgggc agtctcagac
     6781 cggtggccgc gccgagccgg ttgcgcaggt cgacggcggt gaccgactcg aagccgagtt
     6841 ccttgaaggc gagccgggcg tcgaccgcgg cgggcccgtc gaacccgagc agtgcggcca
     6901 cctgccggcg taccagtgcg agcagggagc ggtatcgctc cggcggggtc aggtccgcca
     6961 gctcggcggc gaggtcgcgg ccgttggtgc cgtccgggtc gtcggccggt gtcgcggcgg
     7021 ccgggtcggg gagcgtctgc agctcgggca gcgcgtccag gagcgggcgc cgcctggcga
     7081 gggtgtagac gggcaggaag cgcccccagt cgatgtcggc gacgacgagg ccgctctcgt
     7141 cgtggtcgag ggccttctgc agcgcctcga tcgcgaggga cggtggcagt tgcggcaggc
     7201 cgagcgagcg gaggtgtccg gccgcgtcgt caccgaccat gccgccgccg ccccagggtc
     7261 cccaggccac cgaggtcgcg gtcagcccgc gggcgcggcg gcgctgggcc agggcgtcga
     7321 ggtgggcgtt ggcactggcg tacgcggtct gcccggccgt gccccagacc gcggcacccg
     7381 aggagaacag gacgaacgcg tccagcgggc ggtcggcgag cagcgcgtcg aggtgttcgg
     7441 cgcccgcggt cttggcgcgg gtgatcgcgg cgaactcctc gagcgtggtc tcggtgacgg
     7501 gcttgccctc ccccagtaca ccggcggcgt gcacgacggc ggtgagcggc tggtcggcgg
     7561 gcagaccgtc gaggagccgg gcgaggtcgt cgcggtcggc ggcgtcacag gccgcgaccg
     7621 tgacctcggt gccgagtgcg acgagctcgg cctccaggcc ggcgatgccg tcggccgtgc
     7681 gtccgcgccg cccggcgagg acgacatggg cggcgccgga ccgggcgagc caccgtgcca
     7741 cgtgtccgcc gatcgcgccg gtgccgccgg tgacgagcac ggtgccgcgc ggccgccacg
     7801 cgcgtaccgg ctcccggtcg ccgagcggtg cgcgcgtcag gcgccgggcg tagacgccgg
     7861 aggggcggaa ggccagttgg tcctcgcccc gggttccggg ggcgtccagg cgggagcaga
     7921 gcagccgcac cgtgcgcacg tcggcgccgg ccggcaggtc ggcgatgccg ccccaggtca
     7981 gcgggtggtc gagagccagg acggtgccca ggccccagac ggcggcacgc tcgggcacgg
     8041 gcggctcgtc gtggctgtcg acggcgacgg caccgctggt caggcaccac aggggggcgg
     8101 tgtgcccgag gtccgcgagt gcctgtacga gggtgacggt ggcggtggtg gcccgcgcga
     8161 gcgcggggtg tgcggggtgc gtgcgggtgt ccagcgacag cagggacacg acgcggtcgg
     8221 gcggctcgcc cggcagcgcg gcgcgaatgc gctcggcgag gccggcccgg tccgcgtcgt
     8281 cgggcacctc gacggtgacg agccgggggc cgtgggcgcg cagtccgtcg aggacggtgc
     8341 gcggcaggcc cgtgtgggga ccggagtcgt ccgcgggtgg tgcgggcacg acggcgagcc
     8401 aggtgccgga cggggtggcg tcggcggggg ccgtgaccgg ctgccaggtc atgcggtagc
     8461 gccaggagtc gacggtggcg gcgtcgaggc gggcacggcg ccacgcggcg agcgcgggca
     8521 ccacgtcccg cagcggtgcg gcgtcggccc cgatcagccg ggccagcgag tccgcgtcgc
     8581 cggactccac ctcgttccag aacgccgcgt ccggtgcggt gtccggcgtg gccgccgagg
     8641 cgcggtcggt gtccggggcc tgcgcccagt agcgacggcg ctggaaggcg taggtgggca
     8701 ggtcggccgg ttcggcctgg gggtgcaggt cgggccagcg ctggggcacg ccccgcacat
     8761 ggagctcgcc gagcgcggtg agcatcctgg gcagcccgcc ttcgtcccgg cgcagggtgc
     8821 ccacgacgac ggtgtccgcc ggggtcgccg cttgcgcgcg gtccgcgacc gcgtccaggg
     8881 tctcctgcac gctcatggtc agtacgggat gggggctgac ctcgatgtac gtggtgtgcc
     8941 cctgcgcggc caaccggtcc accgcggagg cgaactcgac ggtgtggcgc aggttggcgt
     9001 accagtaggc ggcgtcgagc tgtccgtcgg ccacgaactc gccggtcacg gtggacagca
     9061 tggggaccgt gccccggccg ggtgtcagcg gggccaggtc gcgcagcagt tgctcctcga
     9121 tccgggcgac ctgcgcggag tgcgaggcgt agtccacggg tatccggcgg gcccgcacct
     9181 tctcggcgcg gagttcgtcg agcagcgcgt cgagcgcgtc cgcgtccccg gagacggccg
     9241 tggagcgggc tccgttgacg gcggcgacgg acagctcgtc cggccgccgg gcgagacgtg
     9301 cgcgcagttc ggcggcgggc agcgccaccg aggccatgcc gccgggtccg gcgagcccgc
     9361 gggcgatggc ccggctgcgc agggcgacca cgcgtgcgcc gtcctcgagt gacagcgcac
     9421 cgctgacaca ggcggcggcg atctcgccct gcgagtggcc gacaacagcg tcggggtgga
     9481 cgccgtactc ctgccacagc gccgcgaggg acaccatcac cgcccacagc aggggctgta
     9541 cgacgtcgac gcggtccatc gcggggctgt ccggtgcgcc gcgcagcacc tcgcccggcg
     9601 accagtccag gtagggggcg agcgccttct cgcagtccgc gaaccgctgg gcgaaggccg
     9661 gtgcgccggc cagcagttcc gtggccatcc ccgtccactg cgagccctgt ccggggaaga
     9721 cgaacacggt cctgccgcgc acgtcggcac ggccggtggg caccgacgcc gggggcgtcc
     9781 cggctgccag ggcacgcagg ccggcgacca gctcgtcccg gtcgccgccg acgacgacgg
     9841 cccggtgggc gaagggcgaa cggccggtgg ccagggtccg cgcgacgcct gcgggcgagc
     9901 gccccgggtt ctcctccaga tacgtcgcga ggcggtcggc ctgggcggtc agcgcgtccg
     9961 gggtcttcgc cgacaggggc caggcgacgg ccgtaccggc ggacgccccg tcgtccggca
    10021 cccggtcgtc cggtgtccgc gggtgggcgt cctggggcgc ctgctcgatg acgacgtgca
    10081 cgttggtgcc gctgatgccg aaggaggaca cggcggagcg ccgcggccgg ccggtgtcgg
    10141 gccagtggac cggctccgtg agcagccgca cctgcccggc ggaccagtcg acgtgccgcg
    10201 tcggttcgtc cacgtgcagg gtcttcggca ggattccgtg ccgggtggcc atcaccatct
    10261 tgatgacggc cgccgctccg gccgcggcct gcgggtggcc gatgttggac ttgacggaac
    10321 cgagccacag cggccggtcc tcggtgcgtc cctgcccgta cgtggcgatg agcgcctgcg
    10381 cctcgatggg gtcgccgagc gtggttcccg tgccgtgtgc ctccacggcg tccacgtccg
    10441 cggtgtcgag cccggcgtcc gcgagagcca gccggatcac ccgctgctgc gcgggcccgt
    10501 tgggcgccga gatgccgttg ctggcgccgt cctggctgac cgcggagccc cgcacgacgg
    10561 ccagcacggg gtggccgttg cgtacggcgt cggagagccg ttccagcagg agcaggccga
    10621 cgccttcgga ccagttggtg ccgtccgccg cttcggcgaa cgacttggcc cggccgtcgg
    10681 gtgccaggcc ccgctggcgg ctgaagtcca cgaacatctc gggcgtgccc atcacggcgg
    10741 ccccgccggc gagagcgagg tcgctctcgc ccttgcgcag cgactggcag gccaggtgca
    10801 gcgcgaccag ggacgacgag cacgccgtgt ccacggtgta ggcggggccc tcgagaccga
    10861 gcgtgtaggc gatgtgcccg gaggcgaagg cgccgccggg gctgccgccg gcgtagtcgt
    10921 ggtacatgag gccggcgaac acccccgtgg cggtgccttt gaggctgccc gggtcgatgc
    10981 cggcgcgctc gatcgtctcc cacgccactt cgaggaggag ccgttcctgc gggtccgccc
    11041 gcagtgcctc gcgcgggctg atcccgaaga aggcggcgtc gaactcggcg gcgtcgtgca
    11101 ggaatccgcc gtgccgcacg taggtcttgc cggggcggcc gggggtgggg tcgtagatcc
    11161 cctcggtgtc ccagccgcgg tcgacgggga acccgctgat ggcgtcggtg ccgtcggcga
    11221 ccagacgcca caggtcctcc ggggtctgca catcgcccgg gtaccggcag cccatggcga
    11281 cgacggcgac gggctcgtgg gccctcgcct ccacgtcccg caggcgctgc ttggtgtgcc
    11341 gcaggtcggc ggtggcgcgc ttgagatagt cccgcagccg ttcctcgccc gtcatcggcg
    11401 gtccccccgt tccgaggccg ttcccggccc tgtctctggt gctgatcgcg tgcggtcggc
    11461 gacgtcggac ggcccgtcgg cgtgcggtcc caactcccgg tccagcgccg cgaagagctc
    11521 gtcgtcggtg acgatgtcga ggtcctgctc cgcctcgtgt tccggctccg gtccctggac
    11581 cgtgtgccac ttgcgctgca gcgcctccag gcgggccgtg atccgcgcga gggcggccgg
    11641 gtccgccgcc gggccgctcg tgccgtcacc gccgggtgcg ccgttctggg cggacagcgc
    11701 gaggagcgcg gcctccagtt ggtcggcctc ggcgaggacc gcctcgaccg gtcccagtgg
    11761 tgcggatacc agctcggccc gcagatggcg gaccagggct tccgcgtcag ggtggtcgaa
    11821 gacgagggtg gccggcagct tgaggccggt cgccgtcgcg agcgcgttgc gcagttcgac
    11881 cgccgccagg gagtcgaagc ccaggtccgt gaaggacctg ccgggttcca tggcgtcggc
    11941 cgacccgtat ccgaggacct ccgcgacgtg ccgtccgacg agttccgtga gggtcctgtc
    12001 ctgctcggcg ggggacagtc cggacagccg ctcggcgagg tccgggccct cctgcgcccg
    12061 cccggccgtc cccgcggagc gccggacggc agggcctcgg gcgaagcccc gcagcaccgg
    12121 cggcagttga ccgccgcggg cccgcaggac cggcacatcg agccgtacgg gcaccagcgt
    12181 ggccgcgtcg gcggcgaggg ccgcgtcgaa cagagcgagg gcgtccgccg tggccagcgg
    12241 cggcaggccg agccggtcga ggcgttcgcg tcccgccctg tcgaggcggg ccgccatccc
    12301 gtcgctctcc gcccagagcc cccaggccag ggacaacgcg ggcagtccct gagcccggcg
    12361 gtgctgagcc agaccgtcga ggaacgtgtt cgccgcggcg tagccccctt gtccggcgcc
    12421 gatgaggtaa ccggcggcgg aggagaagag gacgaacgcc gacaggtccc tgcccgccgt
    12481 cagttcgtgc aggtggtggg cgccgtcggc cttgggccgg agcaccgtct cgacctgctc
    12541 gtcggtcagt gagccgacga gggcgttgtc gacgacgcct gccgcgtgca cgaccgcggt
    12601 gagcgggtgc gctgccggga tcgagtccag cagcgcggcc agtgcctcgc ggtcggcgac
    12661 gtcgcaggcg gccacgcgta cgtcgaccgg ggccagtgcc gtcagctccg ccaccaggtc
    12721 gcgggcgccc gccgcctcga tgcccctgcg gccggccagc accaggtggc gtacgccgtg
    12781 ttcaccgacg aggtgccggg cgagcagggc gccgagacca ccggtgccac cggtgatcag
    12841 cacggtgccg gaggggtccc aggcgccgga cgccgggggc gccgggggcg ccggggccgc
    12901 ggcggggacc agacgaggca cgagggtctt ccccgcccgc agggccagct cgggctctcc
    12961 cgaggcgatg gctgccgtga gcgaccgccg ggacgcctcg tcgtgatcga tgtccgcgat
    13021 gtcgtgatcg atgtccgcga tcacgatgcg tccggggtgc tcggcctgcg cggcgcgcac
    13081 caggccccac accgcggctt ccgccgggtc caccgtggtg tcgcccgctt cgacggcgtt
    13141 gcgggtcagc acgaccagcc gggtcgcggc gagccgctcg tcggccagcc aggaccggag
    13201 ccgtgccagc acccccaggg tgcgggcccg gacgtcggcc ggtgcgccgg tcggcatgcc
    13261 gggagggcag gacgccgacg tgtgtggcgt cggcgtgccg tcgtccgcgg cgacgatcag
    13321 cacctcggga gcgggggctc cggccgcgag gtccgccagg agcgcggcga ggccgtcgtc
    13381 gtgacgcgcc gtttccccgc cgccgccaag aagcgcgccg accgggacgt ccgcccgtcc
    13441 gaccgtgacc cagcccgccg tgtcggccgg ctcgtccgtc gtcgcggcga cgctccagtc
    13501 gagccggaag agcgactcgc cggcggccgt gccccggccg gtgccgagct gctccggcga
    13561 cacgggccgt acggcgaggg accgcacgga ggccacgggc tcgccgtcgg catcggccag
    13621 cgtcacggac acggctccgt tgtccgcacc ggtgggcgct atgcgcacgc gcagcgaggt
    13681 ggcgccgacg gcgtgcaggg tcacaccgtt ccaggcgaac ggcagcaggg tccgtccggt
    13741 gccggtgccg gtgtcggccg tgtcggtgcc cgtgccgagg agctgggcgt gcagcgccgc
    13801 gtcgagcagg gcggggtgca gggcgaacgc gtccgtgccg gccggtccgt cctccggaag
    13861 ggacacctcg gcgaacagtt cctcgccgcg gtgccagacc gcacgcaggc cggcgaacac
    13921 cggtccgtag tcgtacccga gggccgcgag ccgctcgtag gcaccgtcga tgtcgacgga
    13981 cgccgccttc tccggcggcc agacggtgag ttccccggac tccgtccccg tcccgtcgtc
    14041 ctccgaggtg aggactccgg tcgcgtgccg gtcccaaggt gcgtcgtccg gtacgccctc
    14101 ggtacgggag tagaccgtga cgggtcgtcg tccgctctcg tcccgctccc cgacgacgac
    14161 ctggagagcg acggccgtgt ccgtggcgag ggtgagcggg gccgccagcg tcagttcttc
    14221 cagcacggga aggcccaagc ggtctccggc ctggatggcc agttccacga acgcggtgcc
    14281 gggcagcacg acgttgccca gtacctgatg gtcggccagc cagggtgcgg tgcccagggc
    14341 caggcgcccc gtcagggtga ttccgcccgt ctccggggcg accacggccg ctccgagcag
    14401 agggtggccg ggggacacca gtcccgcggc ctccacctgg gacggggcct caggcgtcag
    14461 ccagtagagg cggcgctgga aggcgtaggt gggcaggtcg atccgctcgg cgccctggcc
    14521 ggcgaagaag gcttcccagt ccaccgtgac accgcgctcg tggagccggc ccacaccctc
    14581 gaccagcgac agcacctcgt cccggccttt acgcagcaac ggcacaccca ccgcaggcga
    14641 accctcagcg accgagtcgg ccaccatccc cgacaacacc gaccccggac ccacctccac
    14701 gaacgacacc acacccgccg cctccaccac ccccaccgca tccgcaaacc gcaccgccga
    14761 cgaaatctgc tccacccaat accccggcga cgacatcacc cccgccccca ccaccccacc
    14821 cgacaccgac gacaccacac ccacacccac cggatcaccc aactccaacc cctccaccac
    14881 accccggaac tcctccaaca ccccatccat caaccccgaa tgaaacgcat ccgccacctc
    14941 cagccaccgc acccgccgcc ccaaccccac aaaccccgca accgcctcct ccaccgcacc
    15001 ccgcaccccc gacaacacca ccgaccgagg accattcacc gcccccaacc acacaccccc
    15061 acccaacaac ggcaccacct caccctccga cgcctccacc gccaccatca ccccacccgc
    15121 acccacaccc tccatcaacc gaccccgcgc acccaccaac acacacgcat cctccaacga
    15181 caacaccccc gccacccacg cagcacacac ctcccccacc gaatgaccca ccacccaatc
    15241 cggccgcacc ccccacgaac ccaacaaccc caccaacccc acacccaccg caaacaaccc
    15301 cgcctgcgcc acacccgtcc ccacaccaga ccccagctcc acctcaccaa acaccacatc
    15361 cctcaacccc acccccaccg gcaacacccc acccaactca ccctccaaca acccacacac
    15421 cccatcaaac gcctcagcaa acaccggaaa caccccatac aacccacgcc ccatccccac
    15481 ccacccagac ccctgccccg gaaacacaaa ccccgtccca cc
//
