LOCUS       NZ_BBOK01000019        31962 bp    DNA     linear   CON 17-AUG-2024
DEFINITION  Streptomyces sp. NBRC 110030, whole genome shotgun sequence.
ACCESSION   NZ_BBOK01000019
VERSION     NZ_BBOK01000019.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. NBRC 110030
  ORGANISM  Streptomyces sp. NBRC 110030
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Katano-Makiyama,Y., Hosoyama,A., Hashimoto,M., Tsuchikane,K.,
            Uohara,A., Kitahashi,Y., Ohji,S., Ichikawa,N., Kimura,A.,
            Yamazoe,A., Komaki,H., Igarashi,Y. and Fujita,N.
  TITLE     Whole genome shotgun sequence of Streptomyces sp. NBRC 110030
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 96168)
  AUTHORS   Hosoyama,A., Kimura,A., Ohji,S., Ichikawa,N., Yamazoe,A. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2014) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 97x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina HiSeq 1000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001417675.1-RS_2024_08_17
            Annotation Date                   :: 08/17/2024 02:44:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,240
            CDSs (total)                      :: 7,152
            Genes (coding)                    :: 7,019
            CDSs (with protein)               :: 7,019
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 4, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 45 of 133
            Pseudo Genes (incomplete)         :: 107 of 133
            Pseudo Genes (internal stop)      :: 8 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:33:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6679
            Orig. end                         :: 38641
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBOK01000019.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..31962
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..31962
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31962
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[10000:21962]"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..21962
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            1419..2135
                     /locus_tag="APK71_RS34230"
     CDS             1419..2135
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="APK71_RS34230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159042909.1"
                     /transl_table=11
                     /translation="MPTTAMSSSCPVDVVLSLRREKTARLLRTMRPYHMLPALSHSWGS
                     APAYMSLLRRPDGLAVLDVSEDGGTDRLEQRVRVLSTISSVVVLAPRDVDVVATLRAGA
                     VNVLPRDTPPRELAGRIVAERRWIDLSSRRQRLRAPSQSRPQVVPHQASQQVLLELLSL
                     PSREWCCHDLGLLLGTAGEPVSKRALQARVMRLNGRLAPYGVSVDAVHRWGRTRYSGVR
                     EAVPYEVPPAQSPLRL"
     gene            complement(2197..2880)
                     /locus_tag="APK71_RS34235"
     CDS             complement(2197..2880)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016433911.1"
                     /locus_tag="APK71_RS34235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_055469926.1"
                     /transl_table=11
                     /translation="MESVRVLLVDDQQMIRTGFRLILECEPDIAVLGEASDGDSAVEQV
                     LALRPDVVLMDVRMPGTDGVEATRRIVESGAEAQVVMLTTFDLDRHVLDALRAGAVGFL
                     LKDGPAQSLVEAVRMVAAGDAVLSPRVTRRLLDRFARLPQPAVGAASRRLEHLTAREVD
                     VLRALSRGLSNEEIAQELDVSKNTVRTHIAHILEKYHLRDRVQAVILAYDAGLVTPVGH
                     ASTVR"
     misc_feature    complement(3046..3059)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.04"
                     /tool="antismash"
     misc_feature    complement(3200..3218)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 19.34"
                     /tool="antismash"
     gene            3409..3834
                     /locus_tag="APK71_RS34240"
     CDS             3409..3834
                     /EC_number="1.11.1.15"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004601 - peroxidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /GO_process="GO:0006972 - hyperosmotic response [Evidence
                     IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /GO_process="GO:0033194 - response to hydroperoxide
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983301.1"
                     /locus_tag="APK71_RS34240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="OsmC family protein"
                     /protein_id="WP_055469927.1"
                     /transl_table=11
                     /translation="MATTRSAHTVWEGNLLEGNGVVTFDSSGIGEQPVSWPSRAEQANG
                     RTSPEELIAAAHSSCFSMALSHGLTGAGTPPTKLTTSADVTFQPGEGIKGIHLTVEGTV
                     PGLDNDTFVAAAEDAKKNCPVSQALTGTTITLTAKLA"
     gene            complement(3920..4516)
                     /locus_tag="APK71_RS34245"
     CDS             complement(3920..4516)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012862.4"
                     /locus_tag="APK71_RS34245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="caspase domain-containing protein"
                     /protein_id="WP_370592583.1"
                     /transl_table=11
                     /translation="MGSFISSQTETDLTADDMRLAIGEFLTACDEDELALLYISGHGAR
                     RVREGGEFYVVARDTDFDRAAETGVSAGFFDELLEQCVAPQKVVMIDCCRSGGFAVGLR
                     TSDQQPDGAVAKSGEPALLTSRGMMTAGGPLDDLGTRIRPEAGTPPCAEQTRDDKKGAG
                     PPPVRVAGRRGRAGLRWQRRGLPTSNRNYVSSAGA"
     gene            5846..6772
                     /locus_tag="APK71_RS34255"
     CDS             5846..6772
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="APK71_RS34255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159042910.1"
                     /transl_table=11
                     /translation="MGTPTLELAVGVTSASLDRGLEQLHARHRELLRGDHSEVMSGVRY
                     SLKWDLRKPPRISLGAPDAARWRKTWKQGSASTLPSSGVVQLVMPELWLQWAAEGGSSR
                     ELSCSVAVPAGLLAVDGGVRVDPLGVWMETPPADSNDRTVLKRVLVPRLLERGGDLLKA
                     LRLPAQQFLGQSVDLTPVLVDVTDRYLVVATGSRPDPSSGSAVDWPTGKEVFCLVAPAL
                     VKRLVNAAAQQEADKHEPVVDVDETLTGVLQATLKAYFRGLKDLRVDARDPTRLTAGVD
                     VAWKGGVTLFPIAPGEGCALVEATQNM"
     gene            6789..7724
                     /locus_tag="APK71_RS34260"
     CDS             6789..7724
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="APK71_RS34260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159042911.1"
                     /transl_table=11
                     /translation="MTRSDLVVALGQDTLNDLLRSSASRPGVRDALMAGTLQVPVGGRS
                     VPLEWSLGEPPVLSLHDPTDDEWRAAIGPRGASPRRVGGAFTVLLPRLTVSGPGIKRAT
                     RRVKVLCLLAAGSGTLGITPLGAELDLRHVPDPSDRAVYRHIVVPRALQAALGPLGGTA
                     LPRVSVAGLSFGDFALTAGAGMVVGAANTDDRPPAPAPDPVALFPRAPAFEVLLSRPAL
                     ERAARAAVSGLTGRSQSVGGSSSFGIGRAQYEGRVHVNAADARVAGNPLDLDVDISLAV
                     HAEAGIDLFQDIGEALNHAAEGIGRALSSY"
     gene            7765..8145
                     /locus_tag="APK71_RS34265"
     CDS             7765..8145
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="APK71_RS34265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_030403515.1"
                     /transl_table=11
                     /translation="MSDIGISYNASVLPEPLRVRVRLHLTGTTVRATLEDVPGFVTTLR
                     PVGNVGEQILSGVAWPVAQTLGILLPQVGNRLLAGQSFDLLPLPAPPPLRLNGQTLTPV
                     LDNPSLSSRDGMLRFTASLRLA"
     gene            8177..8542
                     /locus_tag="APK71_RS34270"
     CDS             8177..8542
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="APK71_RS34270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_055469931.1"
                     /transl_table=11
                     /translation="MALMDFKTITVPDPPEVTVRAGTAPDGKLTLKLVDLKLSDVSFLP
                     LSVAAVPVGILSMLLSKPTASAVRKFFTDQTLDVPLPQPLGTSFPAGDTEVKVRLDQPE
                     LGSHNGMLMISGTASVS"
     gene            8582..9997
                     /locus_tag="APK71_RS34275"
     CDS             8582..9997
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151965.1"
                     /locus_tag="APK71_RS34275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_055469932.1"
                     /transl_table=11
                     /translation="MNDPHVSPDGEPSAAEPLRLADTPGYPLARGVDTTDIDTVPYDTG
                     ALSIRFGDLTLQPLAAPAAVSSEVLGEVTKVTYRIPALSLTGRYALDARPDEISTIDAG
                     GNPFQPLTAEQQEPTFPAAPAPHTPPDEQTQERWHGRARAHRDALMRTENGRKLLVEYG
                     KHNDTYCEVFAGTDSVSKALRKTWRTGGVTRRMAEHTYSVTDPGTPSGEQEPVNEWTDD
                     ESGVSYNGHAWSQRTLLVTTLMTKAGSRRRKGDDHNAERYEAAAEAAESFSLEVQQTGN
                     AGGDTTPLTQQQVYQTVEDHSGTVSPPSAEAMARYQPPAGPEELMTREAPGATAGAEPD
                     GWVALGAQDHAVIENIHRAFYHQEAAEAGPADNTLHLGQVSARLEDVRITVKLPAGPGG
                     LPTEPEDIEVVLPEFDLSVQDEHWEGNAGAVAKERLAGMSFLLGLLRDSTAETLRHSVL
                     AGTPGYTPPTEGA"
     gene            10001..11029
                     /locus_tag="APK71_RS34280"
     CDS             10001..11029
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151964.1"
                     /locus_tag="APK71_RS34280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_055469933.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.5e-46, bitscore:
                     151.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLILDKGTAPEDVAGSVWAELLAEDLVRYEATLEEALEPQREYLS
                     EAEYTVYRRGKRLRPAVLLLAARMVHGPTPLPAKVLQGAVSLEMLHVATLIHDDVVDDS
                     MLRRGMPSVNAARGPGTAVIVGDLQFVQAVRGFVDAIDHDRDMALVKLVLDSAFDTCRG
                     ELDELHTDLSQEPAALVNRYWQTADRKTAVLFGLAAEAGVVLADGRSSDARRAGFYGRG
                     FGRAFQVMDDLFDLARAEAASGKPCGVDLLRGRASLPLIYAMAELGPGHLVSRVMRGEL
                     AGPSALARAVAQVRAGGGFARAYADARTQALDALEFLRPFPDNPYRRALHDLALHVVDR
                     AP"
     gene            11123..12889
                     /locus_tag="APK71_RS34285"
     CDS             11123..12889
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="APK71_RS34285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_055469934.1"
                     /transl_table=11
                     /translation="MGTALVNFVYTTMKKRLNNPGSRYWLPTLLKEVKAPDGGTLTPLR
                     AAEWKLGPIGGEQGTLVGDTIAKAWWTAVADAFDDAQGREDESKNLPEDLDAFTPRRSE
                     ANPLPTLSFSSVEIHHLPNAAVGELTGLTEDSDGYRGSVRITLGAHHCGEWKDRDQIRI
                     KSRYLLCQEVVAADDPDDDSTGPLPPTTTVARGLKGVSWPKQVVEGRGTLELTARDLAF
                     DVQVALHVSGRGPGRTLAARVDSISLAAGVTPTFCLDGKDLTIEDEWTDPKLIESWKRA
                     ALKAVNSPDAGRELRAAMEAALSDPGQRDEFSMVVTQQLAAALDGVLGPVSTGALPVEG
                     SDTRPGPVEQYLFDRVRHAVNSPTSSFYPPAVIHSLDDPVLVPYRIPLLDLGPQSVEGI
                     ELSAVRLHDVTVHGLPNLLIPPEDARLTADGIDLTLRLGRITDRPDIPGTRGADGSPLR
                     VPEPPLVLTGRFEADFPPSGEDEDDVLSGTFKASLTRPSLAAGLVFSGPDADALEISLR
                     SLDLELTAEEVTVDVTTGDLFREVIRSLFNSTQVKTVLLHGMRERTAARKDEIAAGLST
                     AARGIIAAHLTQ"
     gene            12971..16654
                     /locus_tag="APK71_RS34290"
     CDS             12971..16654
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="APK71_RS34290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_055469935.1"
                     /transl_table=11
                     /translation="MHVQELDALLTRRTTDRTISLSSDDFGCAAAPLVTEWLDGTLTVT
                     GVRRSTRPDGTVVLDGTTSLLGVKDRPVTGIEIGLDPADQRPSLYLPFALPTTWNFPVS
                     FPETKDSGLARLGFATEPELLLSSTVRPAADGRPSLLPGLTFHGATVRTPDAAEWLGEL
                     LALASGALSLTGPITRTPGPKDKRRADIALASPPRGAGVLGASFRVWAGSRTTTAADGT
                     STVAYPVRLRADLTLAPGTKATVGAPLPSGTEKVTLTAEVLPSEPQPTASLASWDGSGS
                     ALRQLTDQGFGLGDSVLLTELGLVIDPDKLREGLTEAVTEVTVKASARPTVAWTVAKSV
                     EVTEVGAELTVTRPLTRKRGATVTGYGTFTVTPALHLTASARIPPGTFQLAQHKDTTAK
                     LADVLAGFLPSAPAGPDLTLSEFSGSATPKTGEYSLTAKVATSWSLSLGAAEVELTGGT
                     LKLDRKKKEKKKEEKEGKKEKGEEGGEKQGEKEEEGATAEDPTDHPDSSHEVTGTVSAT
                     AKLGAAGGDRTVDFTATWTLPQSFALEGTFPEIELTELLKRLSCPLELPDGTPAVVLKK
                     SKATLRAGKAMAGQPAADVHYELGLSTNVTFGTRTQHPLTLTGKAGRSAEGTFFAAALW
                     QRDWSWSPKDVEGWGDVLGVLGDLTFRKSGLAICTADGVTLDADAKLPDTLPRTLGRGL
                     TFFTEVGYGEPLAFLRQIFPDTEGIRLRARLTRSIADSEFTAVIGEEDTGSGFGALSLT
                     IVPKDRKIQLSTSFLLDLSAFGSPSGTSLRFVAAGDVAKTDIGWTFSLGLVLRAEEAGG
                     PALPGQPTPQQLSVVTLDRPGHILLPTTDPTPTTAVVPTTRGMPGDLPLAPVSKQRSVW
                     RNAFGIEGFDIAYFYLEMRYGTDGFKLGGGGSVDIGPASLELAVHGRVSPPSVSAFYFS
                     LTGTSPERGVTVLDLVKIVAPDPPAALSPLDSVVVREVALCAVADPDGWTNRATGQNWA
                     PGFYARGDVAFGTNTWQFQVRIQPTGLYVSSQVREPIELGGVFKFAGRDGITGPQFLLD
                     TGDLKAGRLPEKIFYLSGSLSLLGHQVLAVEALLERGGFAFDLAVDIVAVRVGVHCRLN
                     EQGLKARARVDLGFDITLPRDAQIAGIPLGAGLLVGVRVGGEIEVDVASGAMVRLSGAF
                     SLRALDTTLVSTEAELSFGIRSWNDVVNVLKEDPAKVLEKVATDVWETAKNCAVTTAGA
                     LM"
     gene            complement(16629..17546)
                     /locus_tag="APK71_RS34295"
     CDS             complement(16629..17546)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="APK71_RS34295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159042912.1"
                     /transl_table=11
                     /translation="MLETPEVSALRRRLHGRVREVVSRMPRPLAEDVAALLGRHGRTRT
                     ADQGDLFVLFPAPVWSFLHWVPAAGHPDAERLHAAALLLHLWDDHLTDRQLAPDLAALQ
                     LRTELWRCLEQDAAALCAAWGADSGLVARHTERYLCATHAPRTPADLDSYCSLAREQAA
                     LWTLLPRLLETGGRAEAGWSSLVEDFAVAWRLVDDAADVRRDAVAGIRSAVWWELPAAG
                     RARWDERARRPGRDDVSGYVLGDAQQDGSEEAGCAEAVGRVLARAAALLAAAADRAAAA
                     GEEGVATELLTARAGVLTSVRRPW"
     gene            complement(17600..19048)
                     /locus_tag="APK71_RS34300"
     CDS             complement(17600..19048)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1261: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF013714.4"
                     /locus_tag="APK71_RS34300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_055469937.1"
                     /transl_table=11
                     /translation="MAAWRRVLGEAHVLTAPEDRAAAGRCTFPAPRPEAVLCPADAAQT
                     RDCLRIAHHHGVRVHPVSTGRNWGYGSGCPPVEHTVVLRLARLDRILGHDEQLGLVTVQ
                     PGVTFGQLAEALGQRSPEWLPPSTGAGPSTSVLANALQRGQGRGPYQDMASHLRRLEVV
                     RPDGTRLSTGPGPGPGLTGLFLQGGPGVVVSAELWLHPRPRAGRSVIFRLPDERLLPGA
                     VDAARRLLQRTPGGVAVSLWNRARLAAQVLPAPRSRLPEHLGGPWTGYAELWADDPRAL
                     DLRYESVLRAFAPYADHWDSDDVTGHAAAPGAPGPPEGAARYDSAPGLASAYRHKPGGP
                     LYVPAGRERDPDRDRCGVLWFTPQLPMSGARTDTVLRLVERIMTDRGMEPCLALRLGAR
                     DLRCVTGLFWDRDEPGADARALECRRELVRRCARIGVHPCRPVTGDDLGDAGNEGSRLL
                     LDQVASVLDPRGILRARPRRASGR"
     gene            complement(19321..19680)
                     /locus_tag="APK71_RS34305"
     CDS             complement(19321..19680)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="APK71_RS34305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_158716741.1"
                     /transl_table=11
                     /translation="MAAAVQVQPRRVFNYDQLSAAVGGAGAGISTAAIGNHLDPQSFWR
                     DAFLYAAPVLAIVVSVLVNWGCAAAERREIAQGIKRAMATVQEEIEDPTTTLARKEELR
                     SMLRALRDEKIAHRI"
     gene            complement(19685..20011)
                     /locus_tag="APK71_RS39075"
     CDS             complement(19685..20011)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040404.3"
                     /locus_tag="APK71_RS39075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_234353292.1"
                     /transl_table=11
                     /translation="MGRAASGLGVWLSRCSARADALRVAVRTTCDAGGPKGGEVEIESL
                     IAVLGSLTAVSAMARTIALWARSRHPKRVRVQDGEDEVSFDLSNRSEALRFLEKVVDPD
                     RKVR"
     gene            complement(20076..21050)
                     /locus_tag="APK71_RS34315"
     CDS             complement(20076..21050)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669514.1"
                     /locus_tag="APK71_RS34315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_055469938.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.8e-52, bitscore:
                     168.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVAATPADDTCVPLLEAELLRRVGSGDSLLELACLDALFPSGKL
                     LRPVLCVESAKAVGGTADQVLAFAAGIECLHVASLVHDDIIDQDPVRRGRASTAEQYGL
                     AEALVAGDGLSMTGIAALLGAGPAERVLHAARVTVEALRHMCQGFMRETEIRGDLTCGV
                     PTVLDVMQAKTAALTGAACQAGAILAGAAPRQHQALRRYGERLGMAFQIRDDLLPYTTD
                     DRVTGKTTTSDVANLQPTLPVLLAYEAADETDRNRLAAVFRGGTDPVTAHRDVLTVLTR
                     TGALTKAARMASSCAGQAHTELAGLPDSTRLAELATSAADRQH"
     gene            complement(21069..21962)
                     /locus_tag="APK71_RS34320"
     CDS             complement(21069..21962)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004981463.1"
                     /locus_tag="APK71_RS34320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="squalene/phytoene synthase family protein"
                     /protein_id="WP_055469939.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.2e-35, bitscore:
                     113.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.3e-20,
                     bitscore: 64.4, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVRRWLDAADITDPVLRHCYTTCVRELATADGGTARWHGLRSAR
                     AEARPHAAALLAHGCRADRCVDTGPVGDRRRRFAAFADATWAAFAAGGSHDPVLHATVH
                     TYRTFGLPQSVVEDMFTAMRRDFDFRDFATFEELRRWCVRMTGGPMAMVYRVTGAVADP
                     AQELPVRELSVFAQLTDALRDLSEDLDDGRLYLPLEDLDRFDVRAEDIKAKRWTPGMAD
                     LVAFETERVTERLHAAAEVDLGPLSGLWHAHREHMAVIIDAVLAAGQDVLHRPVQPPLG
                     TLLHVWRPLMRTVIPC"
     gene            complement(22077..22922)
                     /locus_tag="APK71_RS34325"
     CDS             complement(22077..22922)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669512.1"
                     /locus_tag="APK71_RS34325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_053638063.1"
                     /transl_table=11
                     /translation="MRRHVRLYLTAARFDLVEHARNRLAMVLVALFIPAWTSLAHAVIP
                     SRTVTFRLRATGRLLAPAGNQITQITGAINAVTLITGFMMFAVTFSGGRFDRRLAMSGY
                     PRIHLVLAKSTSLALASGIIAAYATAVICTAWSPRQPVQLAAALFCGAMTYGALGVVFG
                     SLLRREVEGMFALVMTSLVDVGLQSPLASGGTESAAVHLLPTYGTMQAATAAGFTGHPL
                     PGDLAAQALWFAGAALLGLLAFHRRTKDALTARRPFRLPRPPGHRPPAPPAARAPSAPR
                     "
     gene            complement(22919..23524)
                     /locus_tag="APK71_RS34330"
     CDS             complement(22919..23524)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004981460.1"
                     /locus_tag="APK71_RS34330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_055469958.1"
                     /transl_table=11
                     /translation="MKVRDVRHAYGRREVLRGLDLDLPPGVLAGIVGENGAGKSTLLKI
                     LSGELRPQRGSVRHGGRFGYCPQDVVVNDALTVRQHLEFFRVARGLPDLRHTAEVMEAL
                     RLTEYADERTGALSGGTRQKLNLTLALMHDPQVLLLDEPYQGFDWDTYQRFWDLAARLR
                     DAGRSVLVVSHLAYDAERLDELWRLRGGVLHPATAVPA"
     misc_feature    23644..23658
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.02"
                     /tool="antismash"
     gene            complement(23740..24621)
                     /locus_tag="APK71_RS34335"
     CDS             complement(23740..24621)
                     /NRPS_PKS="Domain: Abhydrolase_1 (30-129). E-value:
                     1.1e-24. Score: 79.3. Matches aSDomain:
                     nrpspksdomains_APK71_RS34335_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014151107.1"
                     /locus_tag="APK71_RS34335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_031185816.1"
                     /sec_met_domain="PF00561 (E-value: 1.3e-20, bitscore: 66.4,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.2e-15, bitscore:
                     49.7, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMDDHTSTPLRTGRAAVNGTSLHYRTAGTGPAVVLLHGVPKTGYH
                     WRHLVPKLTPHHAVVVPDLRGLGDSARPASGYDSATMSDDVAELMARLGHETYAVVGED
                     WGAVIGYQLAARHREHATALVFAEALFPGFGFEEHTALTPENVSGGMHLWHLGFYFQPD
                     VPEMLIAGHERELITYMIKNERSHPDTATPDAIEEYVRCYSLPGGIRAMLAVYRAMLTD
                     AEQNRRAAREKLDIPVLALGGSAFLGERNEDQARLVAHDVTGHVFDAGHDLAEEVPDEM
                     AAVVLPFLAGHR"
     aSDomain        complement(24235..24531)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS34335_Abhydrolase_1.1"
                     /evalue="1.10E-24"
                     /label="APK71_RS34335_Abhydrolase_1.1"
                     /locus_tag="APK71_RS34335"
                     /protein_end="129"
                     /protein_start="30"
                     /score="79.3"
                     /tool="antismash"
                     /translation="PAVVLLHGVPKTGYHWRHLVPKLTPHHAVVVPDLRGLGDSARPAS
                     GYDSATMSDDVAELMARLGHETYAVVGEDWGAVIGYQLAARHREHATALVFAEA"
     gene            complement(24820..25398)
                     /locus_tag="APK71_RS34340"
     CDS             complement(24820..25398)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003977736.1"
                     /locus_tag="APK71_RS34340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_031084435.1"
                     /transl_table=11
                     /translation="MARTREFDTEAAVSRAMDLFWTRGYEATSVRDLTQHLGIGQGSLY
                     AAFGDKDGLYRAALEHYRTTLAADALRSLEEGAGARAAIRALLTERIRIAVGSGGKGCL
                     AVNAVCERVPQDAATRRTVREMQEASREALAEVLRAAAERGEIAARHDPHTAAAFLITF
                     LNGLLVTSKITPDARSLEPLVEVALTALD"
     gene            complement(25471..26220)
                     /locus_tag="APK71_RS34345"
     CDS             complement(25471..26220)
                     /NRPS_PKS="Domain: PKS_KR (8-160). E-value: 3.3e-12. Score:
                     38.6. Matches aSDomain:
                     nrpspksdomains_APK71_RS34345_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669777.1"
                     /locus_tag="APK71_RS34345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_031084434.1"
                     /transl_table=11
                     /translation="MHRLEGKHALITGGTSGIGLETAREFLAEGATVAITGRSRERLDA
                     AARQLDGPLLTIVSDAGDVPGQAALAARLREEWPKLDVLMSNAADVTHLPIEAWTEEAF
                     DRLVATNLKAPFFLIRDLLPLFAQPSSVILVGSVSAYIGHENATVYGAAKAGLLSYTRG
                     LTHELKDRGVRVNGLSPGPTVTNAFASLGPERRAALYEELRQTVPLHRLGTATELAKAA
                     VYLASDESAYTAGTVLRVDGGIGQLAY"
     aSDomain        complement(25741..26196)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS34345_PKS_KR.1"
                     /evalue="3.30E-12"
                     /label="APK71_RS34345_PKS_KR.1"
                     /locus_tag="APK71_RS34345"
                     /protein_end="160"
                     /protein_start="8"
                     /score="38.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALITGGTSGIGLETAREFLAEGATVAITGRSRERLDAAARQLDGP
                     LLTIVSDAGDVPGQAALAARLREEWPKLDVLMSNAADVTHLPIEAWTEEAFDRLVATNL
                     KAPFFLIRDLLPLFAQPSSVILVGSVSAYIGHENATVYGAAKAGLLSY"
     CDS_motif       complement(26104..26193)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS34345_0001"
                     /evalue="2.10E-08"
                     /label="PKSI-KR_m1"
                     /locus_tag="APK71_RS34345"
                     /protein_end="39"
                     /protein_start="9"
                     /score="26.8"
                     /tool="antismash"
                     /translation="LITGGTSGIGLETAREFLAEGATVAITGRS"
     gene            complement(26235..26972)
                     /locus_tag="APK71_RS34350"
     CDS             complement(26235..26972)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (6-165). E-value: 2.8e-11. Score:
                     35.6. Matches aSDomain:
                     nrpspksdomains_APK71_RS34350_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669776.1"
                     /locus_tag="APK71_RS34350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_055469940.1"
                     /sec_met_domain="adh_short_C2 (E-value: 8.3e-34, bitscore:
                     110.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFAGKTALVTGSGAIGGLGHATAKVLAAGGADLILTGTDPQRGA
                     QVVADLGATAGSVRFVAADLSDAAGAHGLAEEAGAVDILVNNASLMTFSPTTGQDLVSY
                     ETAFAVNVRAPFLLTALLAEKMAAGGGGSVVNVSSTAAGLGMPGMAVYGATKAALESLT
                     RTWAAEFAASGVRVNAVAPGPMRTSKVVAAMGPDMGGMGLATALQRTSDPAEVAQVVAF
                     LAGDRASYMTGAIVAADGGRTAI"
     aSDomain        complement(26478..26954)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS34350_PKS_KR.1"
                     /evalue="2.80E-11"
                     /label="APK71_RS34350_PKS_KR.1"
                     /locus_tag="APK71_RS34350"
                     /protein_end="165"
                     /protein_start="6"
                     /score="35.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGSGAIGGLGHATAKVLAAGGADLILTGTDPQRGAQVVADL
                     GATAGSVRFVAADLSDAAGAHGLAEEAGAVDILVNNASLMTFSPTTGQDLVSYETAFAV
                     NVRAPFLLTALLAEKMAAGGGGSVVNVSSTAAGLGMPGMAVYGATKAALESLTRT"
     CDS_motif       complement(26481..26561)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS34350_0001"
                     /evalue="3.90E-04"
                     /label="PKSI-KR_m4"
                     /locus_tag="APK71_RS34350"
                     /protein_end="164"
                     /protein_start="137"
                     /score="13.0"
                     /tool="antismash"
                     /translation="SSTAAGLGMPGMAVYGATKAALESLTR"
     misc_feature    complement(27021..27030)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.37"
                     /tool="antismash"
     misc_feature    complement(27066..27081)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.47"
                     /tool="antismash"
     gene            27090..27743
                     /locus_tag="APK71_RS34355"
     CDS             27090..27743
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016468535.1"
                     /locus_tag="APK71_RS34355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_051909040.1"
                     /transl_table=11
                     /translation="MARTGRPREFDREQTLERALTLFWSRGYGATSIQDLVDALAVERG
                     SLYGTFGDKRRFYLEAVRLYWEVYERHLTATLDTSPLLPALREILTHPARLDELISDMG
                     VPQGCLVGNTTAELVPQDGEATEVVTRSYHRFTDIVTDALRRAQAAGEVTDEARPEAQA
                     HMLLYLVQGLSLVSRAGLDRAAALAAIDTAVDGLRARPKPSGATRGGPVHEPAG"
     gene            complement(27910..29373)
                     /locus_tag="APK71_RS38605"
     CDS             complement(27910..29373)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="APK71_RS38605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_199829970.1"
                     /sec_met_domain="Pkinase (E-value: 5.5e-42, bitscore:
                     136.2, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEELRAGDPDRIGAYRLVGRLGAGGMGQVFLGRSAGGRPVAVKVV
                     RPEYGADAGFRRSFAREVEAARRVGGFFTAQVVDADPDAERPWLVSAFVPGPSLHTVVG
                     AHGGLPTRALRVLAAGLAEGLDAIHRCGLVHRDLKPGNVVLAADGPRVIDFGIARALEA
                     TSHTVSGVAPGTPAYMSPEQARGDREVGPASDVFALGSVLTFAATGRGPFGDGHPAAMM
                     YRIVQEEPDLTPVDHELRGLVAACLAKDPDARPTPVDLLGSLSHDDAADAWLPPAITRM
                     INEFGAAHGVGTTSAHDGVTTLADADAPDDETAVHGPRDGDTRTDGTAPGAPPSSPPRR
                     RGLARLIPTRRKDGAGTPEDAGPAPFGERSVAQGWNGLPWGARVADFRARFPDAAQQNG
                     EWWVTGRGPETFCGITMDTQYAFNNRGEMSLVVFYPEPRDRERLPVSVLETLGAPDGTS
                     TRWTRGKVVVDVKVAGVVATLTHTGFADR"
     gene            29751..29924
                     /locus_tag="APK71_RS38240"
     CDS             29751..29924
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="APK71_RS38240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_159042914.1"
                     /transl_table=11
                     /translation="MREAAHHLPEVPDAPARPVAAVTDAMAGVLGEEIREEAVVTLAGV
                     PDGRTGIAGTVA"
     regulatory      29975..30196
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
ORIGIN
        1 cgtcgcctcg tgcccgaccg cgcggggcag ctcttcggcc cggccgcccg acgcccggcc
       61 gtgcgcatct gccagaaagc gcccggagcg gtggaggaac cgcaggtccc ccacggtctc
      121 gaggacgcgg gaagcgggcc cgagcctcgt ccgttcgagc aggtggcccc ggatcctccg
      181 gtgcagttct gcgaatccgg ccggatcacg ccagcgtaga tcggctctca gcgcctcgcg
      241 tacgacggcg tggggggcca caccgagccg ggtggtctgg acgaacggct ggtcgcgcag
      301 ccagaggaag agatcctcgc cctggtcacc gaggaccgcc cgcagcaacg ccaccgaagt
      361 gacacgggcc tgggcgcaca cgtccagggc tgcctggtga gcctcgtcgg gcggggtacc
      421 gacgaggcgg cgcagcagag tggcgacggc gtcctggccc agcggaggat ccgcgtgatc
      481 ggcaccgcca tcggtctccg tgcgcaccgc cgcctccgcg gccagggcga gagccagggg
      541 atgccctccg gtgaactcca gcagcgcatc gtgcaggtga gggagaacgc ctcgctgcct
      601 gaggaacgcc gctgcgtcgg gcttactcag accgcccacg ggcagtacac gcagcagccc
      661 cgtccagccc gggtcggccg gccagtgagg gtcaggctcg tgacggctcg ccacgacggc
      721 cacggtgccc caggggaggc ggggtaggca ctcctcacgc aaccagtcct ccaaggaccg
      781 gcagtgctcg aaggaatcga cgagcagaac ggctccaggc tcccgcgtga cgggacgtac
      841 ggcacgcgtg aacgcatcgg cggtcgccgg cgtggtccgc ccgtcgaccc gtacgacggt
      901 gcggcctgcg gcacgggcct ccagcgcgaa ccggcgcaag agcatcgact tgcccgtgcc
      961 ctccggaccg tgcaggtaga gaacgcaggc ggcgccggat gctccgtgca acgctgcgcg
     1021 gaagaagtgg agctcatccc tgcgtccgag gaatgaacgc tcccggactc gttccaaccg
     1081 ccggcccagg ctgccgccgc gcgtgctcac tcactccgcc tctccgtccc gcccgacgcg
     1141 cccgggccgc cgaccgcgac agcgcggagc gcggccgcga cgggagtact ccgagaggag
     1201 catatgcgtc cgtgcatcac cacgggcggc cgcccacgag gggcggagag ttcgtcgccc
     1261 ctgcaccctc ggcggccgcc gttgagcaca ggtgagcaca tgacgaccac cgcttgagca
     1321 gccggtggcg cgcgggggtg ccgagcatgg aacggacccg ccacacgagt accacccccc
     1381 gccacacgag taccaccccc atgcccatgc ccatgcccat gcccacaact gcgatgtcct
     1441 cctcctgccc cgtcgatgtc gtcctctcgc tacgccggga gaagacagcc cgtctgctgc
     1501 gcaccatgcg cccgtaccac atgctgccgg ccctgtccca ctcatggggc tccgcaccgg
     1561 cctacatgtc gctgctgcgc aggcccgacg ggctggccgt cctcgatgtg tcagaggacg
     1621 gcggaacgga ccgactcgag cagcgcgtgc gcgtgctcag cacgatctcc tcggtcgtgg
     1681 tgctggcgcc ccgggacgtg gacgtggtcg ccacgctgcg tgcgggggcc gtcaacgtgc
     1741 tcccccggga cacccctcct agggagttgg ccggacggat cgtcgccgaa cgcaggtgga
     1801 tcgatctctc ttcgaggcgt caacgcctgc gggcaccgtc ccagagtcgt ccgcaggtcg
     1861 tgcctcacca ggcttctcag caggtgttgt tggaacttct aagcctgcct tcccgtgagt
     1921 ggtgttgtca cgatctgggt ctgctgctcg gcaccgccgg ggagccggtg agcaaacggg
     1981 cgctgcaagc ccgtgtgatg cgtctgaacg gacgtctggc gccgtacggg gtctctgtcg
     2041 acgccgtaca ccggtggggc cggaccaggt actcgggtgt acgcgaggcc gtgccgtacg
     2101 aggtgccgcc cgcgcagtcg ccgttgcgcc tctgatttca cgccccggat gcgctgacga
     2161 ctcgttcgtg ggaggccgtc agggaggagc agcctgtcag cggacggtgg aagcgtgccc
     2221 gaccggtgtg accaggccgg cgtcgtaggc caggatcacc gcttgtaccc ggtcacgcag
     2281 atggtacttc tccaggatat gagcgatgtg tgtcctgacc gtgttcttgc tgacgtccaa
     2341 ctcctgagcg atctcctcgt tggacagccc ccgactcagc gcacgcaaca cgtcgacctc
     2401 gcgggccgtg agatgctcca gccgcctgga cgcggccccg acggcgggct gaggcagacg
     2461 ggcgaagcgg tccagaagcc gccgagtgac acggggggac aggaccgcgt caccggcggc
     2521 caccatccgt accgcctcca ccagagactg tgcgggcccg tccttgagca ggaaaccgac
     2581 ggccccggcc ctgagagcgt ccaggacgtg ccgatccagg tcgaacgtgg tcaacatcac
     2641 gacctgggct tccgcaccgg actccacgat gcgccgggtg gcctcgacac cgtccgtgcc
     2701 gggcatgcgg acgtccatca ggacgacgtc cggccgcagg gcgaggacct gctcaacagc
     2761 ggagtcgccg tcggacgcct caccgagaac ggcgatgtcc ggttcgcatt cgaggatgag
     2821 acggaaaccg gtgcggatca tctgctggtc gtcgaccagc agaacgcgga cggactccat
     2881 ggaagaggct tccttcgtgc ggtgcaccgg cgtgcggtgc gggtgaaacg ggcggccgac
     2941 tcgactgccg cccgagcgat gcgctgacga cgagcatgtg taccggctct cgatgacgac
     3001 agatcacgat atctgcacgg gtcgtccggg acgcgctggg tcgatgcgcg cagcgtgacg
     3061 cagccgacgt ggagagacga gaaggcacgc tgctccggcc tggcgactga tcaagccggc
     3121 ccgagagggt tgctccagca actgaggaat catctgtcgg atctctcccc cttcgcctta
     3181 ccgcctcacg tgcccccaca gcatgcagta cacgcttacg cagaagtaaa tcacgatcaa
     3241 cttcgtgaag cgtgccgtcc gggcgagggc ctgcgttcgc gggcggtgct gacaccgcac
     3301 gaccgccggt atcgccgtgg gacaccgtgc cgccgtgaca cgtcctcctg tgatccgatg
     3361 ggctcgctgc cccgatcagg ggccgaaggc tcaacgaagg gaaccaccgt ggcaaccacg
     3421 cgctccgcgc acaccgtctg ggaaggcaac ctgctcgagg gcaacggcgt cgtcaccttc
     3481 gactcgtccg gcatcggcga gcagccggtg tcgtggccgt cgcgcgccga gcaggcgaac
     3541 ggcaggacca gcccggagga gctgatcgcc gccgcccact ccagctgctt ctccatggca
     3601 ctgtcgcacg gcctgaccgg cgccggcacc ccgcccacca agctcaccac ctccgccgac
     3661 gtcaccttcc agcccggcga gggcatcaag ggcatccacc tcacggtgga gggcaccgtc
     3721 cccggcctcg acaacgacac cttcgtcgcc gccgccgagg acgccaagaa gaactgcccg
     3781 gtcagccagg ccctgaccgg cacgaccatc accctgaccg cgaagctggc ctgaaacagg
     3841 ggcggggacc gccacatgac gtgtcgggag ggagccggtt ctgtgacgga actgcggtgc
     3901 agtcccccag aggtctgact cacgcacccg ctgaagacac gtagttgcga ttcgaagtgg
     3961 gcaggccacg gcgttgccac cggaggccgg cgcggcctcg ccggcctgcc accctcacgg
     4021 gcggcgggcc ggcccccttc ttgtcgtccc ttgtctgctc ggcgcagggg ggcgtgccgg
     4081 cttccggccg tatgcgggtg ccgaggtcgt ccagcgggcc gccggcggtc atcatgcctc
     4141 tactggtcag cagggccggc tcgccagact tggccacggc gccgtccggc tgctggtcgg
     4201 aggtgcgtag gccgacggcg aagccaccgc tgcgacaaca gtcgatcatg acgaccttct
     4261 gtggcgcgac gcactgttcc aacagctcat cgaagaaacc ggcgctaaca ccggtctcgg
     4321 ccgcccggtc gaagtcggtg tcccgggcga cgacgtagaa ctcgccgccc tctctgaccc
     4381 gtcttgcacc gtgccccgag atgtacagca gggccagttc gtcctcgtcg cacgccgtaa
     4441 gaaactcgcc gatggccagt cgcatgtcat cggcggtgag gtcggtctcc gtctggctgg
     4501 agatgaagct gccgatattt cacggaccct gctcttcgag ctttatagcc tacgactccg
     4561 cttctgatgg ccatcatggc cgtgtgagcc cggccaagtg gtcggcccct cgggcgaagt
     4621 agcaatcgaa atgcatgagc atgtctcgtc gcgctgggag aaagacgcac cccggtacgg
     4681 acggataagc gggtgcgatc gcaaatcagg cacccgagaa agctacaggc acacgcaccg
     4741 ctcaggagca ccgaccacat catgcgcgcc aacgcgttcg acctcacgtc gaagccgcac
     4801 cggagcgctc cggtgcggct tcgacgtttc acggatccgg gcagagaccc cgccaggacg
     4861 gaccgcggcg cttcgccata tcacccgcgt atcacacagc catcaccagc tggggagacg
     4921 ctctcggacc aagaggctcc gacctgcact ttcatgccca cgggagactg gaacagacgc
     4981 ccctggacgg tctctacaac ctgtgccatg tggtgccgag agacggcccc aggatcagga
     5041 ctggtaggtg ttccggcccg tcaaagcggt attgcagcgt ctcggtcttg ccttcggtca
     5101 cgggttcaca ccttcatctg tcacgatctg tcacacgccc cctgcgagac ctccccatgc
     5161 ctccgccgcg ggaagcaggt ccgccacgtc cggcttcacg tgccacttct tcgtcgtctt
     5221 cacgttcgtg tgcccggccc acctggcgag caggtgatcc ggcaccccgt tgtcggcgaa
     5281 gtacgtgagg caagacgccc gagcatcgta cagacggacc ctgcggaggc cgtttgcgtc
     5341 cattgttctg caggcccgcg ttcgaggctg ccggccgttc ggcggggccc cgaggtcgcg
     5401 gcggcacagt ccatccttgc ccggaaaccg ccgagaaggg gcggaaggct gcggacacat
     5461 aaggggcgac aagcggcatt cgtgcttgaa tggcctacag gaccggccaa ggtccctttg
     5521 tgcggtttgc agcccccgat cggcacgccc gtcgggctgg aggtgagcac catggaggac
     5581 ttcttcgccc agcacgacga ctggccgtgg tgccggactc gtccagcgcc gcgtcgaggc
     5641 cctgcggcac gggagggggc cgaggtgcag accctcgtcc cgccagctcg atccgggcgc
     5701 aggggcgcgg ccggccgggc gggtcccggg tctccacgcg tgagcgcaca acccggctcg
     5761 cacggggccg gaccacgcct ccccggttga gtgaacggca cgagaagggg caggtgaggg
     5821 aggattttcc tgccaaggtc tccgtatggg aacccccaca ctcgaactcg ccgtcggagt
     5881 aacctccgcg tctctggaca gagggctgga gcagttgcac gcccgtcaca gggagctgct
     5941 gcgaggtgac cacagcgagg tcatgtccgg cgtccggtac tccctcaagt gggaccttcg
     6001 gaaaccgccg aggatctccc tgggcgctcc cgacgccgct cgctggcgga agacctggaa
     6061 acaggggagc gccagcacgc tgccctcctc cggagtggtc cagttggtga tgccggagtt
     6121 gtggctccag tgggctgcgg agggcggttc gtcccgtgag ctgagctgca gcgtggcggt
     6181 gcccgccggt ctgctggccg tcgacggcgg ggtccgggtc gatccgctcg gggtgtggat
     6241 ggagactccc ccggccgaca gcaacgaccg gacggtcctc aagagagtcc tcgtcccccg
     6301 actcctcgaa cggggtgggg acctgctgaa ggcgctcaga ctccccgccc agcagttcct
     6361 gggccagtcc gtggacctca cgcccgtcct ggtggacgtc accgacaggt acctggtcgt
     6421 cgccaccggg tcgcggccgg acccctcctc gggctccgcg gtcgactggc ccaccggcaa
     6481 ggaggtcttc tgcctggtcg cccccgcgct ggtgaaaagg ctcgtcaacg cggccgcgca
     6541 gcaggaggcg gacaagcacg aacccgtcgt cgacgtcgac gagacgctca caggggtgct
     6601 ccaggccacg ctcaaggcgt atttccgcgg gctcaaggat cttcgggtcg acgcccggga
     6661 tcccacccgg ctcaccgccg gtgtggacgt cgcctggaag ggcggcgtca ctctcttccc
     6721 catcgccccc ggcgagggct gcgcgctcgt cgaggccacc cagaacatgt gacgaggagc
     6781 gtgcccgcgt gacccgaagc gatctcgtgg tggccctggg acaggacaca ctcaacgacc
     6841 tcctgcgcag ctcggcgtcc cgtcccggag tgcgcgacgc cctcatggcc ggcacgctcc
     6901 aggtgcccgt cggtggccgg agcgtcccgc tcgagtggtc gctgggagag ccgccggtgc
     6961 tgtcgctgca cgaccccacc gacgacgagt ggcgggcggc gatcggcccg cgcggcgcct
     7021 cgccccgccg ggtgggaggc gcgttcaccg tgctgctccc ccggctgacc gtcagcggcc
     7081 cgggcatcaa gcgggccact cggagggtga aggtcctgtg tctgctcgcc gcggggtccg
     7141 ggacgctcgg catcaccccg ctgggtgccg aactggacct gcggcacgtc ccggacccca
     7201 gcgaccgggc cgtctaccgg cacatcgtgg taccccgggc gctccaggcc gcactgggtc
     7261 cgctgggcgg taccgcactg ccccgtgtca gcgtggcggg actctccttc ggcgacttcg
     7321 ccctcaccgc cggagccggc atggtggtag gtgccgcgaa caccgacgac cggcctccgg
     7381 ccccggctcc cgatcccgtc gccctgtttc cccgggcccc cgcgttcgag gtgctgctgt
     7441 cgcggcccgc gctcgaacgc gcggcccgcg ccgccgtgtc cggcctgacc ggccgctcgc
     7501 agagcgtcgg cggaagctcc agtttcggga tcgggcgggc ccagtacgag ggccgggtcc
     7561 acgtgaacgc cgccgacgcc cgcgtcgccg gcaacccgct ggacctggac gtcgacatct
     7621 ccctggccgt ccacgccgaa gccgggatcg acctcttcca ggacatcggg gaggccctca
     7681 accacgccgc ggagggcatc ggccgcgctc tgtccagcta ctgacggcac gcctgcccct
     7741 ccgcacccgc ctccatggag tctcgtgtcc gacatcggca tctcctacaa cgcctccgtc
     7801 cttcccgaac cgctgcgcgt acgcgtccgg ctgcacctga ccggcaccac ggtccgggcg
     7861 acgctggaag acgtccccgg cttcgtcacc accctgcgcc cggtcggcaa cgtcggcgag
     7921 cagatcctct ccggtgtcgc ctggcccgtg gcccagaccc tcgggatcct gctgccccag
     7981 gtcgggaacc ggctgctcgc gggccagtcc ttcgacctgc tgccgctccc cgcgccaccg
     8041 cccctgcgcc tgaacggcca gaccctcacc cccgtcctgg acaacccgtc cctgagcagt
     8101 cgcgacggca tgctcagatt caccgcctcg ctccgcctgg cctgaccccc gctcgccgaa
     8161 agaacaggac ccgtacatgg cactcatgga cttcaagacc atcaccgtgc ccgacccccc
     8221 ggaggtcacc gtccgggccg gcaccgcgcc cgacgggaag ctgactctca aactggtgga
     8281 cctgaaactc tcggacgtct ccttcctccc gttgagcgtg gccgccgtcc cggtcgggat
     8341 cctgtccatg ctgctgtcga aacccaccgc ctcggccgtc aggaaattct tcaccgacca
     8401 gactctcgac gtgccgctcc cccagcccct gggaacgtcg ttccccgccg gtgacaccga
     8461 ggtgaaggtg cggctcgacc agccggagct gggctcccac aacgggatgc tcatgatcag
     8521 cggcaccgct tccgtctcct gacccttccc gcaccgcacc cttcccagga gccctctccg
     8581 tatgaacgac cctcacgtct ccccggacgg cgagccctcc gccgccgagc ccctccgcct
     8641 tgccgacaca ccgggctacc ccctggcccg cggtgtggac acgaccgaca tcgacaccgt
     8701 cccctacgac accggcgccc tgagcatccg cttcggcgac ctcaccctgc agcccctggc
     8761 ggcaccggcg gcggtgtcca gcgaagtcct gggggaggtc accaaggtca cgtaccgcat
     8821 cccggccctg tcgctgaccg gccgttacgc gctcgacgcg cggccggacg agatcagcac
     8881 gatcgacgcc ggcggcaacc ccttccagcc gctgaccgca gagcagcagg agccgacgtt
     8941 cccggctgcc cccgcacccc atacgccgcc cgacgagcag acccaggaac gatggcacgg
     9001 gcgggcccgc gcgcaccgcg acgccctgat gcggacggag aacggcagga agctgctggt
     9061 cgagtacggg aagcacaacg acacgtactg cgaggtcttc gccggcaccg acagtgtcag
     9121 caaggctctg aggaagacgt ggaggaccgg cggcgtcacc cgccgcatgg cagagcacac
     9181 ctactccgtc accgatcccg gcactccctc tggtgaacaa gaaccggtca acgagtggac
     9241 cgacgacgaa agcggtgtct cttacaacgg ccatgcctgg agtcagcgga ccctgctggt
     9301 cacgaccctc atgacgaagg ccggcagccg caggcgcaag ggcgacgacc acaacgccga
     9361 gcgctacgag gcggcggccg aagccgccga gtccttcagc ctcgaagtgc agcagaccgg
     9421 caacgccggc ggggacacga ctcccctgac ccagcagcag gtgtaccaga cggtcgagga
     9481 ccactcgggg acggtgtccc cgccgtccgc ggaggccatg gcgcgctacc agccgcccgc
     9541 cggtccggag gagctcatga cccgggaagc gcccggcgcg accgccgggg cggagcccga
     9601 cggctgggtg gcactgggcg cacaggacca cgcggtcatc gagaacatcc accgggcctt
     9661 ctaccaccag gaggccgccg aagccggccc cgctgacaac acgctgcacc tggggcaggt
     9721 ctcggcacgg ctcgaggacg tccggatcac cgtgaagctc ccggccgggc cgggcggtct
     9781 tcccaccgag ccggaagaca tcgaggtcgt cctgccggag ttcgatctca gcgtgcagga
     9841 cgagcactgg gagggaaacg ccggggcggt ggccaaggag cgcctcgccg gcatgtcctt
     9901 cctcctgggg ctgctgcgcg actccacggc cgagacgctg cgccacagcg tcctcgccgg
     9961 cacgcccggg tacacaccgc ccaccgaggg ggcctgaccg gtgctcatcc tcgacaaggg
    10021 cacggccccc gaggacgtgg ccgggtccgt ctgggcggag ctgctggcgg aagacctggt
    10081 ccgctacgaa gcgactctgg aagaggcgct ggaaccccag cgggagtacc tcagcgaagc
    10141 cgagtacacc gtctaccggc ggggcaagag gctgcgcccg gcggtgctgc tgctggccgc
    10201 ccgcatggtg cacgggccca ccccgctgcc ggccaaggtg cttcagggcg ccgtctccct
    10261 ggaaatgctc cacgtcgcca ccctcatcca cgacgacgtg gtggacgact ccatgctgcg
    10321 caggggcatg ccgtcggtga acgccgcccg cggaccgggc accgcggtga tcgtcggcga
    10381 tctgcagttc gtccaggcgg tgcggggctt cgtggacgcc atcgaccacg accgagacat
    10441 ggcactggtc aagctggtgc tcgacagcgc gttcgacacc tgccgcggcg agctggacga
    10501 gctgcacacc gacctctccc aggagccggc cgccctggtg aaccgctact ggcagaccgc
    10561 ggaccgcaaa acggccgtcc tgttcgggct ggccgccgag gccggggtcg tcctggccga
    10621 cgggcgcagc agtgacgcac gccgggccgg cttctacgga cgtgggttcg gccgcgcctt
    10681 ccaggtcatg gacgacttgt tcgacctcgc ccgggcggag gccgcgtccg gcaaaccgtg
    10741 cggggtggac ctgctgcgcg gccgggcttc cctgccgttg atctacgcca tggccgaact
    10801 gggtcccggc cacctcgtga gccgggtcat gcgcggggag ctcgccggcc cgtcggcgct
    10861 ggcgcgggcc gtcgcgcagg tccgtgcggg cggcggcttc gcccgtgcgt acgcggatgc
    10921 ccgcacccag gcgctcgacg ccctggagtt cctgcgcccc ttcccggaca acccctaccg
    10981 ccgggccctg cacgacctgg ccctgcacgt ggtggaccgg gccccctgag cccagcaccg
    11041 ccacgccgcc cgcccagctt ccagacctgg cccgccgtct ccggcaggac caggcatccc
    11101 aagcccgcga cagggagaca ccatgggaac cgccctggtc aacttcgtct acaccaccat
    11161 gaagaagcgg ttgaacaatc cgggcagccg ctactggctg ccgaccctgc tcaaggaggt
    11221 gaaggccccc gacggcggca ccttgacgcc gctacgggca gcggagtgga agctcggccc
    11281 gatcgggggc gagcagggca cactggtggg cgacaccatc gccaaggcct ggtggacggc
    11341 cgtcgcagat gccttcgacg acgcccaggg gcgcgaggac gagtcgaaga acctgcccga
    11401 ggacctggac gccttcaccc cccgccgaag tgaggccaac ccccttccca cgctgtcctt
    11461 ctcctcggtc gagatccacc acctccccaa cgccgccgtg ggagaactca ccggactcac
    11521 cgaggactcc gacggctacc gggggtccgt ccgcatcact ctgggggccc accactgcgg
    11581 tgagtggaag gaccgcgacc agatcaggat caagagccgc tatctgctgt gccaggaagt
    11641 cgtcgccgcg gacgaccccg acgacgactc gaccggtccc ctgcccccga cgacaacggt
    11701 ggcgcgggga ctgaagggtg tgagctggcc gaaacaggtg gtggagggcc gcggaacgct
    11761 cgaactcacc gcccgggacc tcgccttcga cgtccaggtc gccctccacg tctcgggccg
    11821 gggccccggc cggaccctgg cggcccgcgt ggactccatc agcctcgcgg ccggtgtcac
    11881 ccccacgttc tgcctggacg ggaaggacct gaccatcgag gacgaatgga ccgaccccaa
    11941 gttgatcgag agctggaagc gagcagccct gaaggcggtc aacagtccgg acgccggcag
    12001 ggaactccgg gccgccatgg aggccgccct gtcggacccg gggcagcgcg acgagttctc
    12061 catggtggtg acccagcagc ttgcagccgc actcgacggg gtgctgggcc cggtgtccac
    12121 cggcgccctt cccgtcgaag gatcggacac ccgaccggga ccggtggagc agtacctgtt
    12181 cgacagggtc cggcacgcgg tgaactcccc cacctcctcc ttctatccgc cggcggtcat
    12241 ccactccctg gacgacccgg tgctcgtccc ctaccggatc ccgctcctcg acctgggccc
    12301 gcagtccgtc gagggcatcg agctgagcgc cgtccgcctc cacgacgtca ccgtgcacgg
    12361 cctgcccaac ctgctgattc ccccggagga cgcgcggctg acagccgacg gcatcgacct
    12421 gacgctgagg ctcggccgta tcacggaccg gcccgacatc ccgggcacgc ggggagcgga
    12481 cggctcgccg ctccgcgtgc ccgagccccc cttggtcctc accggccggt tcgaggcgga
    12541 cttccccccg agtggcgagg acgaggacga cgtcctgagc gggacgttca aggcatcgct
    12601 cacgcggccc tcgctggcgg cgggacttgt tttcagcggc cccgacgccg acgcgctgga
    12661 gatctccctg cgctcgctcg acctggaact caccgccgag gaagtgacgg tggacgtgac
    12721 caccggtgac ctcttcaggg aagtgatccg cagtctgttc aactccaccc aggtcaagac
    12781 ggtcctcctc cacgggatgc gcgagcgcac ggccgcgcgg aaggacgaga tcgccgccgg
    12841 gctgtccacc gccgcacgcg gcatcatcgc cgcccacctc acccagtaga ccccgccccg
    12901 gccgacgtgc ggctgcgcgc cgcccccttc cgccccgccg cgtcccgcgg cagaacctcc
    12961 gggatccccc atgcacgtac aggaactgga cgccctcctc acccgacgca ccaccgaccg
    13021 caccatcagc ctcagcagcg acgacttcgg ctgcgccgcc gcgcccctgg tgaccgagtg
    13081 gctcgacggc accctcacgg tcacgggagt gcggcgcagc acccggcccg acgggaccgt
    13141 cgtcctggac ggaaccacca gcctgctcgg cgtgaaggac cggccggtca ccggtatcga
    13201 gatcggcctc gaccccgccg atcagcggcc ctccctctac cttcccttcg cgctccccac
    13261 cacctggaac ttccccgtct ccttcccgga gaccaaggac agcggtctgg cccggctcgg
    13321 cttcgccacg gaaccggagt tgctcctcag ctccaccgtc cggccggcgg ccgacgggcg
    13381 cccctctctc ctccccggcc tgaccttcca cggcgccacg gtgaggacgc cggacgccgc
    13441 ggagtggctc ggcgagttgc tcgccctcgc gtcgggcgcc ctctcactca ccggccccat
    13501 cacccgcacg cccggcccca aggacaaacg ccgtgcggac atcgcgctgg cctcgccccc
    13561 gcggggcgcc ggcgtgctgg gggcgtcctt ccgcgtgtgg gccggctccc gcaccaccac
    13621 ggccgccgac ggcaccagca ccgtggccta cccggtgcgc ctgcgcgcgg acctcaccct
    13681 cgccccgggc acgaaggcga ccgtcggcgc accgctgccc tcggggaccg agaaggtgac
    13741 cctcaccgcg gaggtgctgc cgagcgagcc ccagccgacg gcgtccctgg cctcctggga
    13801 cggcagcggg agcgcgctgc ggcaactgac cgaccagggc ttcgggctgg gcgacagcgt
    13861 gttgctcacc gagctgggcc tggtcatcga cccggacaag ctgcgggaag gactgaccga
    13921 ggcggtgacc gaggtcaccg tcaaggccag tgccagaccc acggtcgcct ggacggtcgc
    13981 gaagtccgtc gaggtgaccg aggtgggcgc cgagctgacc gtcacccgcc cgctgacccg
    14041 caaacgcggt gccaccgtga ccgggtacgg cacgttcacc gtcaccccgg cgctccattt
    14101 gaccgccagt gcgcgcattc cgcccggcac tttccaactg gcccagcaca aggacaccac
    14161 cgcgaagctc gccgacgtgc tcgcgggctt tctgccctcc gcgccggccg gccccgacct
    14221 gacgctgagc gagttcagcg gctcggccac ccccaagacc ggcgagtact ccctcaccgc
    14281 caaggtcgcc acctcgtggt ccctgtcgct gggagcggcc gaggtggagc tgaccggggg
    14341 caccctgaag ctcgaccgga agaagaaaga gaagaagaag gaggaaaagg aagggaagaa
    14401 ggaaaaggga gaagagggag gggagaagca gggtgagaag gaagaggagg gggcaaccgc
    14461 agaggacccg acggatcacc cggactcctc ccacgaggtc acgggtacgg tgtcggccac
    14521 ggcgaagctc ggcgccgcag gcggcgacag gaccgtcgac ttcaccgcca cctggaccct
    14581 cccccagtcg ttcgccctgg aggggacctt ccccgagatc gaactgaccg aactgctcaa
    14641 gcgcctgtcc tgcccgctgg aactgcccga cgggactccg gcggtcgtcc tcaagaagtc
    14701 caaggccacg ttgcgcgcgg gcaaggccat ggccgggcag cccgccgcgg acgtgcacta
    14761 cgaactcggc ctgtccacga acgtcacgtt cggaactcgc acacagcacc ccctgacact
    14821 gaccgggaag gccggccggt ccgccgaagg caccttcttc gccgccgccc tctggcagcg
    14881 ggactggtcg tggtcgccca aggacgtcga gggctggggc gacgtcctcg gcgtcctcgg
    14941 cgacctcacc ttccgcaagt cgggcctggc catctgtacc gcggacggcg tcaccctgga
    15001 cgccgacgcc aagctgcccg acacgttgcc caggacgctg ggccgcgggc tgaccttctt
    15061 caccgaagtc ggctacgggg aaccgctcgc cttcctgcgg cagatcttcc cggacaccga
    15121 ggggatccgg ctgcgggccc ggctcacccg ctccatcgcc gactcggagt tcaccgccgt
    15181 catcggcgag gaggacaccg gtagcgggtt cggcgccctc agcctgacca tcgtgcccaa
    15241 ggaccggaag atccagctct ccaccagctt cctcctggac ctctcggcct tcgggtcacc
    15301 gtccgggacc agcctgcgat tcgtcgccgc cggtgacgtg gcgaagacgg acatcggctg
    15361 gaccttcagc ctcggcctcg tcctcagggc agaggaggcc ggtggcccgg ccctgcccgg
    15421 gcaacccacc ccccagcagc tctccgtggt cactctcgac aggcccggac acatcctgct
    15481 gccgaccacg gaccccacgc ccaccacagc cgtcgtcccg accaccaggg ggatgcccgg
    15541 ggacctgcca ctggcgccgg tgtcgaagca acggtccgtc tggcgcaacg cgttcggcat
    15601 cgagggcttc gacatcgcgt acttctacct ggagatgcgc tacggcaccg acgggttcaa
    15661 gctgggcggc ggcggctccg tcgacatcgg accggcctcc ctcgaactgg ccgtgcacgg
    15721 cagagtcagc cctccctcgg tcagtgcctt ctacttctcc ctgacgggga catccccgga
    15781 gcgcggggtg acggtcctcg atctggtcaa gatcgtcgcc ccggacccgc cggccgccct
    15841 gagcccgctg gactcggtgg tcgtccggga agtcgccctg tgcgccgtcg ccgacccgga
    15901 cggctggacc aacagggcta ccgggcagaa ctgggcgccg ggcttctacg ccaggggtga
    15961 tgtcgccttc ggcaccaaca cctggcagtt ccaggtacgc atccagccca ccggcctgta
    16021 cgtcagcagc caggtgcggg aacccatcga actgggtggc gtcttcaagt tcgccggcag
    16081 ggacggcatc acaggcccgc agttcctgct cgacaccgga gacctcaagg cgggccggct
    16141 tccggagaag atcttctacc tctccggaag tctctccctc ctcggccacc aggtcctcgc
    16201 cgtcgaggcg ctgctggaga ggggcggatt cgccttcgat ctcgccgtgg acatcgtcgc
    16261 cgtccgggtg ggggtccact gccgcctcaa cgaacagggg ttgaaggccc gggcccgtgt
    16321 cgacctcggc ttcgacatca ccctcccccg cgacgcccag atcgccggga tccccctggg
    16381 cgccggcctg ctggtcgggg tgcgcgtggg cggtgagatc gaggtcgatg tcgcctcggg
    16441 ggcgatggtc cggctcagcg gcgcgttctc gctccgggcc ctggacacca cgctcgtgtc
    16501 caccgaagcg gaactgagct tcggcatccg gtcctggaac gacgtggtca acgtcctgaa
    16561 ggaggacccg gccaaggtcc tggagaaggt ggccaccgac gtctgggaga ccgccaagaa
    16621 ctgcgccgtc accacggccg gcgcactgat gtgagcaccc ccgcccgggc ggtcagcagt
    16681 tcggtggcca cgccctcctc cccggccgcc gcggcccggt cggccgcggc ggccagcagg
    16741 gcggcggccc gggcgagcac ccggcccacg gcctccgcgc atccggcctc ctcggagccg
    16801 tcctgctgcg cgtctccgag gacgtacccg gaaacgtcgt cgcggccggg gcggcgggcc
    16861 cgctcgtccc accgggcccg cccggcggcg ggcagttccc accacaccgc cgagcggatc
    16921 cccgcgaccg cgtcgcgccg cacgtccgcc gcgtcgtcca ccagccgcca cgccacggcg
    16981 aagtcctcca ccagcgacga ccacccggcc tccgcccggc cgccggtctc cagcagccgg
    17041 ggcagcaggg tccacagcgc ggcctgctca cgggcgaggg aacagtagga gtccaggtcg
    17101 gcgggcgtcc gcggtgcatg cgtggcgcac agataccgct cggtgtgccg ggccaccagc
    17161 ccggagtcgg caccccaggc ggcacacagc gccgccgcgt cctgctccag acaccgccac
    17221 agttcggtgc gcaactgcaa cgccgccaag tcgggggcga gttggcggtc cgtcaggtgg
    17281 tcgtcccaca gatggagcag cagcgcggcg gcgtgcagcc gctcggcgtc cggatgcccg
    17341 gcggcgggca cccagtgcag gaaggaccac accggcgcgg ggaacagcac gaacagatct
    17401 ccctggtcgg cggtccgggt ccggccgtgt cggcccagca gggcggcgac gtcctcggcc
    17461 aggggacgcg gcatccggct cacgacctcc cgcacccggc cgtgcaggcg gcgccggagc
    17521 gccgacacct ccggtgtctc cagcaccgca ccgaagcccg ggggcggtgg gactacggag
    17581 gccgggggaa ggaacccgct caccggccgc tcgcccggcg gggtcgcgcc cgcaggatcc
    17641 cccgcgggtc gagtaccgag gcgacctgat cgagcagcaa ccggctccct tcgtttccgg
    17701 cgtcccccag gtcgtcgccg gtgaccggcc ggcaggggtg gacaccgatg cgcgcgcatc
    17761 tgcgcaccag ttcccggcgg cactccagcg cccgcgcgtc ggctcccggt tcgtcacggt
    17821 cccagaagag cccggtgaca cagcgcaggt cccgtgcgcc gaggcggagg gcgagacagg
    17881 gttccatgcc ccggtccgtc atgatccgtt ccaccagccg cagaacggtg tcggtccggg
    17941 cgcccgacat cgggagctgg ggagtgaacc agaggactcc gcaacggtcc cggtcggggt
    18001 cccgttcccg accggccgga acgtacagcg gtccgccggg tttgtgccgg taggcactcg
    18061 ccaggcccgg ggcgctgtcg taccgtgcag cgccttccgg cggcccggga gcacccgggg
    18121 cggcggcgtg cccggtcacg tcgtcgctgt cccagtggtc ggcgtacggg gcgaaggcac
    18181 gcagcacgga ttcataccgc aggtccagcg ccctggggtc gtcggcccac agctcggcgt
    18241 acccggtcca cggcccgccg aggtgctcgg gcagccggct ccgcggcgcg ggcagcacct
    18301 gtgccgccag ccgggcccgg ttccacaggc tcacggccac accgcccggt gtccgttgca
    18361 gcagtcgccg ggcggcgtcg acggcgccgg ggaggagtcg ctcgtcgggg agccggaaga
    18421 tcacggaccg gcccgcccgc ggcctcggat gcagccacag ctcggcggac acgacgacgc
    18481 cgggaccgcc ttgcaggaag agtccggtga gcccgggccc cggtccggga ccggtcgaca
    18541 gccgagtgcc gtcggggcga accacctcca gccgccgcag gtgggaagcc atgtcctggt
    18601 agggaccccg cccctggccg cgctggagtg cgttggccag gacggaggtg ctcggcccgg
    18661 ccccggtgga cggaggcaac cactccggcg agcgctgccc cagggcctcg gccagctgcc
    18721 cgaaggtgac acccggctgc acggtgacca gaccgagctg ctcgtcatgg ccgaggatcc
    18781 ggtccagccg ggccagccgc agcaccacgg tgtgctcgac gggcgggcaa ccggaaccgt
    18841 agccccagtt ccggccggtg ctgaccgggt gcacacggac gccgtggtga tgggcgatcc
    18901 gcaagcagtc ccgagtctgc gccgcgtcgg ccgggcacag caccgcctcc ggccgcggag
    18961 ccgggaacgt acagcgtccg gcggccgccc ggtcctccgg cgcggtgagc acgtgcgcct
    19021 cgccgagcac cctgcgccag gccgccaccg catcggaggg caactccgtc gtgggccgac
    19081 cggcggacac actgtccgaa cccggacgtc cccggacagc gtccggattc ccgctcatca
    19141 tcacccccgg ccggcgagga gcccggtcga ccccgccacc ccgctcctgc ccacgagggc
    19201 ggtccttgtg ctcccgcagg ccggggacca ctcggacgag ggagcgcgcc cgacggccgc
    19261 gcgccttcga gggagcgcgc gaccgggtgg gaatcgcatg ctccggggtc agagagcacg
    19321 ctagatgcga tgggcgatct tctcgtcacg aagggcccga agcatcgatc tcagttcttc
    19381 cttccgcgcg agagtcgtcg tcggatcttc aatttcctct tgcaccgtcg ccatggccct
    19441 cttgatgccc tgggctatct cgcgccgttc ggcggcggcg catccccagt tgaccaagac
    19501 actgaccacg atggcgagca ccggggccgc gtacagaaag gcgtcgcgcc agaagctctg
    19561 cgggtccaag tggttgccga tcgcggccgt gctgatgccg gctcccgcgc ctccgacggc
    19621 cgcactgagc tggtcgtagt tgaatactct tcgcggctgt acctgcactg cggctgccac
    19681 aggatcaccg caccttacgg tccgggtcga cgaccttctc caagaacctc agcgcctcgc
    19741 tcctgttgga gagatcgaag ctcacctcgt cctctccgtc ttggaccctt actcgtttcg
    19801 ggtgccgcga tctggcccag agtgcgatcg tccgtgccat ggcggagacg gcagtaaggc
    19861 tgccgagcac cgcgatcagc gattcaatct ccacttctcc ccctttggga ccacccgcgt
    19921 cgcaggtagt ccggaccgcg acgcggagcg cgtcagctcg tgccgagcat ctgctcagcc
    19981 atactcccaa cccggaggcc gccctgccca ccgttcggca ccagatcgtc gaacccggaa
    20041 gcccgtgacc acccagctcc tcgcggtggt ccggctcagt gctgtcggtc ggccgccgat
    20101 gtggccagtt cggcgagccg ggtggagtcc ggcaggccgg cgagttcggt gtgtgcttgt
    20161 ccggcgcagg aggacgccat ccgggccgcc ttggtgagag cgcccgtgcg ggtcagcacg
    20221 gtgaggacgt cccggtgcgc ggtgacgggg tcggtgccgc cgcggaacac ggcggccagt
    20281 cggttgcggt cggtttcgtc cgcggcctcg taggcgagca ggacgggcag ggtgggttgg
    20341 aggttggcga cgtcgctggt ggttgttttg ccggtgaccc ggtcgtccgt ggtgtagggg
    20401 agcagatcgt cacggatctg gaaggccatg ccgagccgtt ctccgtaccg gcgcagggcc
    20461 tggtgctgcc ggggggctgc tccggccagg atggcgccgg cctggcaggc ggcgccggtc
    20521 agcgcggcgg tcttggcctg catgacgtcc aggacggtcg gcacgccgca ggtcaggtcg
    20581 ccgcggatct cggtttcccg catgaagccc tggcacatgt gccgcagggc ctcgacggtg
    20641 acccgtgccg cgtgcagcac acgttcggcg gggccggcgc cgagcagggc cgcgatgccg
    20701 gtcatcgaca gcccgtcgcc cgccaccagg gcttcggcga ggccgtactg ctcggcggtg
    20761 gaggcccgtc cgcggcgtac cgggtcctgg tcgatgatgt cgtcgtggac gaggctggcg
    20821 acgtgcaggc actcgatgcc ggccgcgaag gcgagcacct ggtcggcggt gccgccgacg
    20881 gccttggccg actccacgca caggacggga cgcaggagct tgcccgacgg gaacagcgcg
    20941 tccaggcagg ccagttccag caggctgtcg ccgctgccca cccggcgcag cagttcggcc
    21001 tccaggagcg gaacgcaggt gtcgtcggcg ggggtcgcgg caacggacat gactcgtcct
    21061 ttcacaggtc agcaggggat cacggtgcgc atgagagggc gccacacgtg gagcagggtg
    21121 cccagagggg gctgcaccgg tcggtggagg acgtcctggc cagcggccag caccgcgtcg
    21181 atgatcacgg ccatgtgttc ccggtgggcg tgccagaggc cgctcagggg acccaggtcc
    21241 acttccgcag ccgcgtgcag ccgttcggtg acgcgctcgg tctcgaacgc gacgaggtcg
    21301 gccatgcccg gggtccagcg cttggccttg atgtcctcgg cgcgcacgtc gaaccggtcg
    21361 aggtcctcca gtggcaggta gaggcgtccg tcgtcgaggt cctccgacag gtcgcgcagc
    21421 gcatccgtca actgtgcgaa gacggagagt tcgcgtaccg gcagttcctg tgcgggatcg
    21481 gccacggcgc ccgtcacccg gtagaccatg gccatcgggc cgccggtcat ccgcacgcac
    21541 caccggcgca gttcctcgaa ggtggcgaag tcgcggaagt cgaagtcccg ccgcatcgcc
    21601 gtgaacatgt cctcgaccac cgactgcggg aggccgaacg tccggtaggt gtggaccgtg
    21661 gcgtgcagga ccggatcgtg ggagcctccg gcggcgaacg ccgcccaggt ggcgtcggcg
    21721 aacgcggcga agcggcgccg acggtcgccg accgggccgg tgtccacgca gcggtcggca
    21781 cggcacccgt gcgcgagcag tgccgctgcg tgcggccgag cctctgcgcg ggcgctgcgc
    21841 aggccgtgcc agcgggcggt ccctccgtcg gcggtggcca actcccgtac gcacgttgtg
    21901 tagcagtgcc gaaggacggg atcggtgatg tccgccgcgt ccagccatcg ccgtaccagc
    21961 atcggtgaac cctctctgct caaccggctc cccttccggg gccggggctt cgctctgtga
    22021 cgcgggcgcg acgcgccccg gggggacccg tgtgagccgt cgcaccgggg cgttgctcag
    22081 cggggcgccg acggggcccg ggccgccggg ggcgctggtg gccggtgtcc gggtggccgg
    22141 ggcaggcgga agggccgccg tgcggtcagg gcgtccttgg tacggcggtg gaaggcgagc
    22201 aggcccagga gtgcggcgcc ggcgaaccac agggcctggg cggccagatc gccgggcagg
    22261 gggtggccgg tgaagcccgc cgcggtggcg gcctgcatcg tgccgtaggt gggcaggagg
    22321 tgcacggccg cgctctcggt gccgccgctg gccagggggc tctgcagtcc gacatcgacg
    22381 aggctggtca tgaccagcgc gaacatgccc tccacctccc ggcgcagcag ggagccgaag
    22441 acgacaccga gggccccgta ggtcatcgct ccgcagaaga gggcggcggc gagctgcacg
    22501 ggctggcgcg ggctccaggc ggtacagatc accgcggtgg cataggcggc gatgatgccg
    22561 gaggccaggg cgagggaggt gctcttggcc aggacgagat ggatgcgggg gtagccggac
    22621 atggccagcc ggcggtcgaa gcgtccgccg ctgaacgtga cggcgaacat catgaacccg
    22681 gtgatcaggg tgacggcgtt gatggcaccg gtgatctgcg tgatctggtt gccggccggt
    22741 gccaggaggc ggccggtcgc gcggagccgg aacgtcacgg tcctgctggg aatgacggcg
    22801 tgggccaggc tcgtccaggc cgggatgaac agggcgacca ggaccatggc gagcctgttg
    22861 cgggcgtgct cgaccaggtc gaagcgggcc gccgtgaggt acagacgcac gtgccgcctc
    22921 acgccggcac cgccgttgcg gggtgcagga cgccgcctcg aagccgccac aactcgtcca
    22981 ggcgctcggc gtcataggcc aggtgcgaga cgacgaggac ggagcggccc gcgtcacgca
    23041 gccgtgcggc caagtcccag aagcgctggt aggtgtccca gtcgaaaccc tggtagggct
    23101 cgtccagcag cagcacctgc gggtcgtgca tcagcgccag ggtcaggttc agcttctggc
    23161 gggtcccgcc gctgagcgca ccggtccgct cgtcggcgta ctccgtcaac cgcagtgcct
    23221 ccatgacctc cgcggtgtgc cgcaggtccg gcagccctcg cgcgacgcgg aagaactcca
    23281 ggtgctggcg cacggtcagg gcgtcgttga ccaccacgtc ctgcgggcag tatccgaaac
    23341 ggccgccgtg acggaccgag ccacgctgtg ggcgcagttc acccgacagg atcttcagca
    23401 acgtcgactt gcccgcaccg ttctccccca cgatcccggc cagcacaccg ggcggcagat
    23461 cgaggtcgag gccccgcagg acctcacggc gaccgtacgc gtgacgcaca tcccgaacct
    23521 tcaccacacc cccgcgcccg aggaccgtgg cacgctcctg ctgctgacca ctcgcgggca
    23581 ccacaaagct aggcaccacg cgcggccaga accggggcat gatcgtcgat tagcccgcac
    23641 gagtgaagat cacgttcttc tccgcgggac cgacgaggga ggcggcgtcg agcggcagag
    23701 ggcgtgtgcg ggccctctgc cgcggcggac ggacgccggt taccggtggc ccgccaggaa
    23761 cggcaggacc acggcggcca tctcgtcggg gacttcctcc gcgaggtcgt ggccggcgtc
    23821 gaagacgtgt ccggtgacgt cgtgggccac gagccgggcc tggtcctcgt tgcgttcccc
    23881 gaggaaggcg gagccgccga gtgccaggac cgggatgtcc agcttctccc gggcggcccg
    23941 ccgattctgt tcggcgtcgg tgagcatcgc ccggtagacg gcgagcatcg cgcggatgcc
    24001 gccgggcagg gaatagcagc gcacgtactc ctcgatcgcg tcgggggtgg cggtgtcggg
    24061 atgactgcgc tcgttcttga tcatgtaggt gatcagttcg cgttcgtgcc cggcgatcag
    24121 catctcgggg acgtcgggct ggaagtagaa gcccaggtgc cacaggtgca tgccgccgga
    24181 gacgttctcc ggggtgaggg cggtgtgctc ctcgaagccg aagccgggga acagcgcctc
    24241 ggcgaagacg agggcggtgg cgtgttcgcg gtggcgggcg gcgagctggt agccgatcac
    24301 ggcgccccag tcctcgccga cgacggcgta ggtctcgtgg ccgaggcggg ccatcagctc
    24361 ggcgacgtca tcgctcatcg tcgcggagtc gtagccgctc gcggggcggg ccgagtcgcc
    24421 gagaccgcgc aggtcgggca cgacgacggc gtggtggggc gtcagcttcg ggaccaggtg
    24481 gcgccagtgg tagccggtct tgggcacgcc gtgcagcagc acgacggcgg ggccggtccc
    24541 cgccgtccgg tagtgcaggc tcgtgccgtt gacggcggca cgtccggtgc gcaggggcgt
    24601 tgaggtgtgg tcgtccatca tgacgtggtg cttcctgtgg tgggtgtgtg cggtgggtcg
    24661 gccgggccgg caggcggccc ggacggtcgg cgccgacggc ggaggcgctg tcggcacggc
    24721 cgggggggat cccgctatct gtatcgaccg ttccattttt ggggcatgag ttcgggacgt
    24781 gagttcggga cgtgcgaacg cccgcaggac gcgggcgtct cagtcgagag cggtcagcgc
    24841 gacctcgacg agcggttcca gactgcgggc gtccggcgtg atcttcgagg tgaccagcag
    24901 cccgttgagg aaggtgatca gaaacgcggc ggccgtgtgc gggtcgtggc gcgccgcgat
    24961 ctcgccccgc tccgccgccg cccgcagcac ctcggccagc gcctcccggc tcgcctcctg
    25021 catctcgcgc acggtgcgcc gggtcgccgc gtcctgaggc actcgctcgc agacggcgtt
    25081 gacggccaga cagcccttgc cgccgctccc gacggcgatg cggatccgct ccgtcagcag
    25141 cgcgcggatc gccgcgcggg cacccgcccc ctcctccaga ctgcgcaggg cgtccgccgc
    25201 gagggtggtg cggtagtgct ccagcgcggc ccggtagagg ccgtccttgt cgccgaacgc
    25261 cgcgtacagc gacccctgtc cgatcccgag gtgctgcgtg aggtctcgca ccgaggtcgc
    25321 ctcgtaacca cgcgtccaga acaggtccat ggcgcggctc accgccgcct cggtgtcgaa
    25381 ttcccgggtc cttgccatga cgtcaccgta ccttatctgg atcggtcgct caagaaagag
    25441 ggtcgcgaca ccgggccgcg gtcgccgtgc tcagtaggcg agttggccga tgcccccgtc
    25501 gaccctcagg acggtccccg cggtgtaggc ggattcgtcc gaggcgagat agacggccgc
    25561 cttcgccagt tcggtggcgg ttcccaagcg gtggaggggc accgtctgcc ggagttcctc
    25621 gtagagggcg gcccggcgct cggggccgag ggacgcgaac gcgttggtga ccgtcgggcc
    25681 cgggctcagc ccgttgacgc ggacgccccg gtccttgagc tcatgggtca gcccgcgcgt
    25741 gtacgagagc aggcccgcct tggccgcgcc gtagaccgtc gcgttctcgt gcccgatgta
    25801 cgcggagacc gagccgacga gaatgaccga ggacggttgt gcgaagagcg gcaacaggtc
    25861 cctgatcagg aagaacggcg ccttgagatt ggtcgcgacg agcctgtcga acgcctcctc
    25921 ggtccacgcc tcgatgggga ggtgggtgac gtcggcggcg ttgctcatca ggacgtcgag
    25981 cttcggccac tcctcccgga gccgggccgc gagcgccgcc tggccgggta cgtcgccggc
    26041 gtcgctgacg atggtcagca gcggaccgtc cagctgccgg gccgcggcgt ccagcctctc
    26101 ccgggagcgg ccggtgatgg cgaccgtggc cccctcggcg aggaactcgc gggccgtttc
    26161 caggccgatg ccgctcgtcc ccccggtgat cagggcgtgc tttccctcaa gtcggtgcat
    26221 ggctctccct cttctcagat cgcggtgcgg ccgccgtcgg cggccacgat cgcaccggtc
    26281 atgtagctgg cccggtcgcc ggcgagaaag gcgaccacct gggccacctc ggccgggtcg
    26341 gaggtccgct ggagtgcggt ggccaggccc atgccgccca tgtccggccc catggccgcg
    26401 accaccttcg aggtgcgcat gggtcccggg gcgacggcgt tgacccgcac gcccgacgcg
    26461 gcgaactccg ccgcccaggt gcgggtcagc gattcgagcg ccgccttcgt ggcgccgtag
    26521 acggccatgc ccggcatgcc gaggcccgcc gcggtggagc tgacgttgac gacgctgccc
    26581 ccgccgcccg cggccatctt ctccgccagc agcgcggtga gcaggaacgg ggcccgcaca
    26641 ttgaccgcga aggcggtctc gtagctcacg aggtcctgtc cggtggtcgg ggagaacgtc
    26701 atgaggctcg cgttgttgac caggatgtcg acggccccgg cctcctcggc cagcccgtgc
    26761 gcgcccgccg cgtcggacag gtcggcggcg acgaaacgca ccgaaccggc ggtcgcgccg
    26821 aggtccgcca cgacctgcgc gccgcgctgg ggatcggtgc cggtcaggat caggtcggcg
    26881 ccgcccgcgg ccagcacctt cgctgtcgcg tgcccgagtc cgccgatcgc cccggagccc
    26941 gtgacgaggg ccgtcttgcc tgcgaattcc atggtcgtgc ctttcacgcc ggccagtgcg
    27001 accgacttct gtgcgtccgt tcaaaaagta atcgcgaccg gaagctacga cttcttgaac
    27061 ggcaagtcaa gaagtcgtag gatcgacacg tggcacgaac cggacgcccc cgcgagttcg
    27121 acagggaaca gacgctggag cgcgcactca cactgttctg gtcccgcggg tacggggcga
    27181 cgtcgatcca ggacctggtc gacgcgctgg ccgtggaacg cggcagtctc tacgggacct
    27241 tcggcgacaa gcgccgcttc tacctcgaag ccgtcaggct ttactgggag gtctacgagc
    27301 ggcacctgac cgccacgctg gacaccagcc cgctgctgcc cgccctgcgc gagatcctga
    27361 cccatcccgc gcggctggac gagctgatct ccgacatggg cgtgccgcag ggctgcctcg
    27421 tcggcaacac gaccgccgaa ctcgtccccc aggacggcga agccacggag gtcgtcaccc
    27481 gctcctacca ccggttcacc gacatcgtca ccgacgcgct gcgccgcgcc caggccgccg
    27541 gggaggtcac ggacgaagcc cgccccgaag cccaggccca catgctgctc tacctggtcc
    27601 aggggctctc gctcgtatcg agggcggggc tcgaccgggc cgcggccctg gcggcgatcg
    27661 acaccgcggt ggacggacta cgggcgcgac cgaagccctc gggggcgacg cgcggcggcc
    27721 cggtccacga gccggccggg tgaacggtgg cgaacggtcc ggctcccggc gtcggcgggg
    27781 cgcggtccgt ccgtacgcgt ccgagcccga ggacggccgg tgtgcacctc gcgccgggca
    27841 gcgacacctt cggcggccgg ggcgtgttcg gagccgagcc gaactcatgg gggcggccgg
    27901 ggccggacct cagcggtcgg cgaacccggt gtgcgtcagg gtcgccacga cgcccgccac
    27961 cttcacgtcc acgacgacct tgcccctggt ccaccgggtc gacgtgccgt ccggagcgcc
    28021 cagcgtctcc aggaccgaca ccggcaggcg ttcccggtcc cggggctccg gatagaagac
    28081 gaccaggctc atctcgccgc ggttgttgaa ggcgtactgc gtgtccatcg tgattccgca
    28141 gaacgtctcg gggccccgcc ccgtgaccca ccactcgccg ttctgctgcg ccgcgtccgg
    28201 gaacctcgcc cggaagtcgg cgacgcgcgc tccccagggc aggccgttcc agccctgcgc
    28261 gacggagcgt tcgccgaagg gggccggacc ggcgtcctcc ggcgttccgg cgccgtcctt
    28321 gcggcgggtg gggatgagcc gtgccagacc gcggcgccgg ggaggggagg agggcggcgc
    28381 gccgggcgcg gtgccgtccg tcctcgtgtc gccgtcccgc ggcccgtgga ccgccgtctc
    28441 gtcgtcgggg gcgtcggcgt cggcgagggt ggtgacgccg tcgtgcgcgg acgtggttcc
    28501 gacgccgtgt gcggctccga actcgttgat catgcgggtg atcgcgggcg gcagccaggc
    28561 gtcggcggcg tcgtcgtgcg agagggagcc gaggaggtcg accggggtgg gacgggcgtc
    28621 ggggtccttg gcgagacacg cggcgaccag gccgcgcagt tcgtggtcga ccggggtgag
    28681 gtccggttcc tcctgcacga tgcggtacat catcgccgcg gggtgcccgt ccccgaacgg
    28741 gccgcggccg gtggcggcga acgtcagcac cgaaccgagg gcgaacacgt cgctggcggg
    28801 gccgacctcg cggtccccgc gcgcctgttc cggcgacatg taggccgggg tgcccggggc
    28861 gacgccgctg accgtgtgcg acgtggcctc cagcgcccgc gcgatgccga agtcgatgac
    28921 gcggggtccg tcggccgcca ggacgacgtt gcccggcttc aggtcgcggt gcacgaggcc
    28981 gcaccggtga atggcgtcga gcccctccgc cagcccggcg gccaggaccc gcagcgccct
    29041 ggtcggcagc ccgccgtggg cgcccaccac cgtgtgcagc gagggcccgg ggacgaaggc
    29101 actgaccagc caggggcgtt ccgcgtccgg gtcggcgtcg acgacctgcg cggtgaagaa
    29161 cccgccgacc ctccgcgccg cctcgacctc ccgcgcgaag ctccgccgga acccggcgtc
    29221 ggccccgtac tcggggcgca ccaccttgac ggcgacgggt cttccgcccg ccgaccgtcc
    29281 gaggaacacc tgccccatgc cgccggcgcc gagtcggccc acgaggcggt aggcgcctat
    29341 gcggtccgga tcccctgctc gcaactcttc catgggcccc cctggtcacc cgacttgggg
    29401 gagatcttcc cagaagcgga cccgatacgc gggccgatga cggcttcgtc ctcccatgcc
    29461 cggcgacttc cggccgccca cggcccgctc ccggcccggc ccgccatccg gggcgtgagc
    29521 accaacaggg ccctgaccgc gtcgtccact cctttcccgt cgccctcgtc ggcaccgtgc
    29581 cctccgggtg ttgacacggc acaccccttc ccgtttgccc gacgcggtcg gcgccctcta
    29641 cggcgaggag tcgggccggc cggggtggac ctggccggcg tcccgtcgca ccgccggggc
    29701 gtcggcggtg tccgcgccga gaccgacgcg ccccgctcgt cactcgcggc atgcgcgagg
    29761 ccgcccatca cctgcccgag gtcccggacg ccccggcccg cccggtcgcc gccgtcaccg
    29821 acgcgatggc cggcgtcctc ggcgaggaga tccgcgagga ggccgtcgtg acgctcgccg
    29881 gcgtgccgga cggccgcacc gggatcgctg gcacggtggc ctgaaccggc gcaccgcggt
    29941 gaatgtcctg ctgttcctcc cccggcccac cccgtaggct gaccacgcag ccggttcgcc
    30001 ccgtccgcca ggcggggtgt cgcaagaggg aacccggtgg gaatccggga ctgccccgca
    30061 gcggtgagtg ggaacgaccg ccgtcatacg cactgggccc gacgtcaggg cccgggaagc
    30121 gacggccagt aggtgtcctc cggtccggag gacgtgctcg cgagtccgaa gacctgccga
    30181 ctgcccgcgt gcggagcgtt ccgcgcgtgg acatcccggt gacctcgagg gcgggtcggc
    30241 gtacacaccg gacggaacgg ccgtgctcgt gcggcgtgga accgttgccg tccggttcgt
    30301 cggacccttc gcgctctcgt cccgtctccg ggatctcagg gattcatctc gcgaaggaga
    30361 tctccgtgac agcgaagtcc gcagccgcgg cagcacgggc caccgtgtac ggctaccccc
    30421 gccagggacc cgaccggcag ctcaagaagg ccgtcgaggg gtactggaag ggccgcgtcg
    30481 gcgccgacgc cctccgcagg accgcgtccg agctgcgccg cggcacctgg cgccggctcg
    30541 ccgacgccgg tgtccacgag gtgcccaccg gcgacttctc gtactacgac cacgtcctcg
    30601 acgccaccgt catggtcggc gcgatccccg agcggcaccg cgccgccgtc gacgccgacg
    30661 cgaccgacgg ctacttcgcc atggcgcgcg gcacccagga cgtggctccg ctggagatga
    30721 cgaagtggtt cgacaccaac taccactacc tcgtcccgga actcggcccg gacaccgtct
    30781 tcaccgcgga ctccaccaag caggtcgccg aactgaggga agctctcgcc gagggccact
    30841 ccgcccggcc cgtgctggtc ggccccgtca cctacctcct cctcgccaag ccggcccccg
    30901 gcgtaccggc cggcttcgaa ccgctgaccc tgctggaccg gctgctgccc gtgtacgccg
    30961 aggtgctcgc cgacctgcgc gcggccggtg ccgagtgggt gcagctcgac gaacccgcgc
    31021 tggtgcagga ccgcagccgg gcggagctgc aagccgccga gcgcgcctac cgcgacctgg
    31081 gcggccgcac cgaccggccc aagctgctcc tggcctccta cttcgaccgg ctcggcgacg
    31141 ctctgccggt cctggcgcag gcccccgtcg aaggtctcgc cgtggacttc accgaggccg
    31201 ccgccgccaa cctcgacgcg ctggccgccg tcggcgggct gcccgggaaa cggctggtcg
    31261 ccggtgtcgt caacggccgc aacatctgga tcaacgactt gcagaagtcg ctgtccaccc
    31321 tcggcacgct cctcggactc gccgaccggg tcgacgtcgc cgcctcctgc tccctgctgc
    31381 acgtgccgct cgacgcgacc gccgaacggg acatcgaccc gcagatcctg cgctggctcg
    31441 ccttcgcccg gcagaagacc gccgagatcg tgacgctggc caagggcctg gcccggggca
    31501 cgagcaccat cgccggtgaa ctcgccgcca accgcgccgg actcgcctcc cgggccggct
    31561 cgccgatcac ccgtgacccg gtggtgcggg cccgcgccgg ggccgtgacg gacgccgaca
    31621 cccgccgctg ccggccgtac gccgaacggg ccgccgccca gcgcgcccgc ctccggctgc
    31681 cattgctgcc gaccaccacc atcggctcct tcccgcagac cggcgaactc cgtgccgccc
    31741 gcgccgacct gcgcgccggc cgcatcggca ccgccgacta cgaagagcgc atcgaggcgg
    31801 agatccagga ggtcgtctcc ttccaggaga agaccggtct ggacgtcctc gtgcacggcg
    31861 aacccgaacg caacgacatg gtccagtact tcgccgagca gctcaccggc tacctcgcca
    31921 cccggcacgg ctgggtccag tcctacggca cccgctacgt cc
//
