LOCUS       NZ_BBOK01000016        21128 bp    DNA     linear   CON 17-AUG-2024
DEFINITION  Streptomyces sp. NBRC 110030, whole genome shotgun sequence.
ACCESSION   NZ_BBOK01000016
VERSION     NZ_BBOK01000016.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. NBRC 110030
  ORGANISM  Streptomyces sp. NBRC 110030
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Katano-Makiyama,Y., Hosoyama,A., Hashimoto,M., Tsuchikane,K.,
            Uohara,A., Kitahashi,Y., Ohji,S., Ichikawa,N., Kimura,A.,
            Yamazoe,A., Komaki,H., Igarashi,Y. and Fujita,N.
  TITLE     Whole genome shotgun sequence of Streptomyces sp. NBRC 110030
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 186614)
  AUTHORS   Hosoyama,A., Kimura,A., Ohji,S., Ichikawa,N., Yamazoe,A. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2014) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 97x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina HiSeq 1000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001417675.1-RS_2024_08_17
            Annotation Date                   :: 08/17/2024 02:44:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,240
            CDSs (total)                      :: 7,152
            Genes (coding)                    :: 7,019
            CDSs (with protein)               :: 7,019
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 4, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 45 of 133
            Pseudo Genes (incomplete)         :: 107 of 133
            Pseudo Genes (internal stop)      :: 8 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:33:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 53332
            Orig. end                         :: 74460
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBOK01000016.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21128
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="1"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21128
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21128
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11128](-)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11128)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    complement(568..582)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.28"
                     /tool="antismash"
     gene            616..1788
                     /locus_tag="APK71_RS32390"
     CDS             616..1788
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016328095.1"
                     /locus_tag="APK71_RS32390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_055469794.1"
                     /transl_table=11
                     /translation="MPKGYSVRSYLAGATAARAGDEMAGPALLLAGLALTGSAAHASSL
                     LAGITVSAAVGGPVLGALLDRAERPGRLLACALALYAVGLAAVLAGLGRLPTAWTVVLA
                     VLTGLLGPALSGGWTAQLPRVAADPHLPRANALDAMTFGAASLAGPALAGGAAEALGAP
                     TAVVLAAALVAAAVPVAWRLPARTGTGPRSRPAPVAGALAAGFRVILRRPPLARATLVS
                     VVCCAAQGVLTACVPLLGARVLGSAGRGALLFSCAAVSALVANAVLARHPRFAAPDTIV
                     RAAALVQAAALALAATGAATGRPAALPVAAVLFGVGEGPQLTALFAVRHRESPEHLRGQ
                     IFTTGASLKVTAFALGAAVAGPLATRSLPGALLVAAGTAAAAAAVGRERV"
     gene            1821..2792
                     /locus_tag="APK71_RS32395"
     CDS             1821..2792
                     /EC_number="2.7.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007268288.1"
                     /locus_tag="APK71_RS32395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_079080723.1"
                     /sec_met_domain="APH (E-value: 3.3e-34, bitscore: 112.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSGQGRREPYDLDERLVRRLVEGQFPRWAGLPLVRHPSAGTVNA
                     MFRLGPDLVVRLPLTGGGAADVTTERQWLPRLAPLLPTAVPEVLGEGVPAEGYPWPWSV
                     YRWLPGELTEAGGLTDPLSLAGDLAGFVAAMRSVTLPGAPAAYRGGPLATLDGPTRAAL
                     DALRDLPEEGVDCEALTEVWQDALHAPAWDGPPRWLHADLMPGNLLVTGGRLSAVIDFG
                     CMGVGDPACDLFPAWNLLPAGAREVFREALGVDDATWRRGRGRTLSQALIALPYYRETN
                     PAMAGNARHVIRAVLGEAERVHRPAKPPAPLGGTDVTSGQLS"
     gene            complement(2780..3886)
                     /gene="paaE"
                     /locus_tag="APK71_RS32400"
     CDS             complement(2780..3886)
                     /EC_number="1.14.13.149"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaE"
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388024.1"
                     /locus_tag="APK71_RS32400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaE"
                     /protein_id="WP_031086647.1"
                     /transl_table=11
                     /translation="MAPTAPVPAAPVRTRRRPAFHTLRVAAVERLCADAAAVSFEIPDE
                     LAREFAFAPGQSLTLRREVDGRDERRSYSICSAAGAAPRIGVRVVPGGLFSAWLVNDVR
                     PGDAVEVMAPTGLFTPDLTTPGHHVLIAAGSGITPMVSIAESVLAADDRSTVTLFYGNR
                     RTDTVMFADELADLKDLHPTRFHLAHVLSREPREAEVLSGRLDAGRLSALIGSLVDVAG
                     ADHWWLCGPQGMVADAQQVLAGLGVPAERVHRELFYADDEPVREVHHEDRGPEGPVSEV
                     TVTLDGRSTTAPLSRERSILDGAQQTRPDLPFACKGGVCGTCRALVTDGSVDMRRNYAL
                     ETAEVDAGYVLTCQSYPVSEKVTVDYDS"
     gene            complement(3886..4404)
                     /gene="paaD"
                     /locus_tag="APK71_RS32405"
     CDS             complement(3886..4404)
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388025.1"
                     /locus_tag="APK71_RS32405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaD"
                     /protein_id="WP_053638956.1"
                     /transl_table=11
                     /translation="MVSDGPALLDARRARHVAEQVPDPELPMLTLADLGVLRDVEVGED
                     GTVVASLTPTYSGCPAMAEMRADVAARLRGAGYPRVEIRTVLDPPWTSDWITEAGRLKL
                     AEHGIAPPGPAPRGGPVPLVLSPTRPAVRCPRCGSADTEETSRFAATSCKALWRCRACR
                     EPFEYVKEI"
     gene            complement(4398..5225)
                     /gene="paaC"
                     /locus_tag="APK71_RS32410"
     CDS             complement(4398..5225)
                     /EC_number="1.14.13.149"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326306.1"
                     /locus_tag="APK71_RS32410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaC"
                     /protein_id="WP_053666076.1"
                     /transl_table=11
                     /translation="MSDDHVYLTLAEGHEDDTRWAYGTGFEDPLHGVDTAVPEGVDAAA
                     LAGECVALADDALVSAQRLAEWVTRAPELEEEVALANIGLDLLGQARLLYSRAGQVDGT
                     GRDEDAYAYFRDAADFRNVRLAELPRGDFAFAVVRLLVLSSWRLAHFRRLGAHPDPVLA
                     AVAVKGVKELTYHRQYAAEWCVRLGDGTDESHRRTRAALDEVAPYLGELHAAYDVRDEV
                     AEDLRQVTEAAGLTLPVYRPLPGSGRAGEHTEHLAPLLTELQGVARAHPEATW"
     misc_feature    5232..5246
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 19.93"
                     /tool="antismash"
     gene            complement(5235..5537)
                     /gene="paaB"
                     /locus_tag="APK71_RS32415"
     CDS             complement(5235..5537)
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971670.1"
                     /locus_tag="APK71_RS32415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaB"
                     /protein_id="WP_053638954.1"
                     /transl_table=11
                     /translation="MTPETPGRQGWPLYEVFVRGKRGLNHVHVGSLHAADDAMALTHAR
                     DLYTRRNEGVSIWVVRSEHIAASTRDEKDPFFAPSADKVYRHPTFYDIPDDVPHI"
     gene            complement(5534..6520)
                     /gene="paaA"
                     /locus_tag="APK71_RS32420"
     CDS             complement(5534..6520)
                     /GO_function="GO:0097266 - phenylacetyl-CoA 1,2-epoxidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031683.1"
                     /locus_tag="APK71_RS32420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="1,2-phenylacetyl-CoA epoxidase subunit PaaA"
                     /protein_id="WP_055469795.1"
                     /transl_table=11
                     /translation="MTTTHAAEAPPPDAPDGLQEHFDATIARDQRIEPRDWMPDGYRKT
                     LIRQIAQHAHSEIIGMQPEGEWITRAPSLRRKAILFAKVQDEAGHGLYLYSAAETLGAD
                     RDDLTQRLVEGRQKYSSIFNYPTLSFADVGVIGWFVDGAAICNQVPLCRSSYGPYARAM
                     VRICKEESFHQRQGYELLMTMMRGTDAQREMVQDAVNRWWWPSLMMFGPPDDASPNSAR
                     SMAWKIKRHSNDELRQRFVDMTVPQAEKLGVTLPDPELRWNEETGHHDFGTPDWDELMR
                     VIKGDGPCNDRRMERRRTAHEDGAWVREAATAHAAKQAARARKGAAA"
     misc_feature    6539..6552
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.77"
                     /tool="antismash"
     misc_feature    complement(6612..6624)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     misc_feature    6657..6672
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.71"
                     /tool="antismash"
     gene            6697..7146
                     /gene="paaI"
                     /locus_tag="APK71_RS32425"
     CDS             6697..7146
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="paaI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971672.1"
                     /locus_tag="APK71_RS32425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hydroxyphenylacetyl-CoA thioesterase PaaI"
                     /protein_id="WP_030403248.1"
                     /transl_table=11
                     /translation="MSQATQRTPTEAMFFADEASRGLGIELVEHGEGTAVLRMTVTPAM
                     VNGHRIAHGGYLFLLADTAFACACNSHGPVTVAAGADIVFVAPAREGDVLVARAEERAR
                     YGRSGIYDVSVRRGGELIAEFRGRSRSVREDTAREAPGTTTKESR"
     gene            7143..8489
                     /gene="paaK"
                     /locus_tag="APK71_RS32430"
     CDS             7143..8489
                     /EC_number="6.2.1.30"
                     /GO_function="GO:0047475 - phenylacetate-CoA ligase
                     activity [Evidence IEA]"
                     /GO_process="GO:0010124 - phenylacetate catabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: AMP-binding (107-352). E-value: 9.7e-20.
                     Score: 62.4. Matches aSDomain:
                     nrpspksdomains_APK71_RS32430_AMP-binding.1"
                     /codon_start=1
                     /gene="paaK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971673.1"
                     /locus_tag="APK71_RS32430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phenylacetate--CoA ligase PaaK"
                     /protein_id="WP_055469796.1"
                     /sec_met_domain="AMP-binding (E-value: 2.4e-26, bitscore:
                     85.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSEPTTGTAPASRPGEPLPHDLLDDAERLSREQLRELQLDRLRA
                     TLRHAYDHVELYRKKFDAAGVTPDDCRSLADLSRFPFTTKADLRDTYPFGMFAVPMSKV
                     RRVHASSGTTGRATVVGYTDNDLSMWADVIARSLRAAGGRPGHKVHISYGYGLFTGGLG
                     AHYGAERAGCTVIPASGGMTARQVQIIQDFRPEIIMVTPSYMLTLLDEFERQGVDPRTS
                     SLKVGIFGAEPWTEEMRREIEERMDIHAVDIYGLSEVIGPGVAQECVETKDGLHIWEDH
                     FYPEVVDPLTDAVLPEGEEGEVVFTSLTKEALPVIRYRTRDLSRLLPGTARPAFRRMQK
                     VTGRCDDMIILRGVNVFPTQVEEVVLRTPGVAPHFQIRLTERGRMDHMTVRVEARPDAG
                     PEQRDAAARAIAQGVKDGVGVTVEVEVVEPETLERSLGKIRRVWDLRGA"
     aSDomain        7464..8198
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS32430_AMP-binding.1"
                     /evalue="9.70E-20"
                     /label="APK71_RS32430_AMP-binding.1"
                     /locus_tag="APK71_RS32430"
                     /protein_end="352"
                     /protein_start="107"
                     /score="62.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="HASSGTTGRATVVGYTDNDLSMWADVIARSLRAAGGRPGHKVHIS
                     YGYGLFTGGLGAHYGAERAGCTVIPASGGMTARQVQIIQDFRPEIIMVTPSYMLTLLDE
                     FERQGVDPRTSSLKVGIFGAEPWTEEMRREIEERMDIHAVDIYGLSEVIGPGVAQECVE
                     TKDGLHIWEDHFYPEVVDPLTDAVLPEGEEGEVVFTSLTKEALPVIRYRTRDLSRLLPG
                     TARPAFRRMQKVTGRCDDMIILR"
     CDS_motif       8166..8228
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS32430_0001"
                     /evalue="5.90E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="APK71_RS32430"
                     /protein_end="362"
                     /protein_start="341"
                     /score="12.7"
                     /tool="antismash"
                     /translation="TGRCDDMIILRGVNVFPTQVE"
     gene            8601..9899
                     /locus_tag="APK71_RS32435"
     CDS             8601..9899
                     /EC_number="1.14.13.-"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FMO-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1092: hypothetical
                     protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971674.1"
                     /locus_tag="APK71_RS32435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_030403250.1"
                     /sec_met_domain="FMO-like (E-value: 4.6e-81, bitscore:
                     266.2, seeds: 5, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.6e-11, bitscore:
                     36.2, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVCVIGAGLSGLAMGHALKSRGISFVCLEKARDVGGIWRQPGAG
                     ERGPGYQTLHLNTAKQLTGYADFPMPSDYPLYPRHTQVAAYLRSFAEWAGLLDHVELRT
                     EVVSVRQDADGGWTVVSRDAEGAQTSRRFEQVVVASGHHNEPALPDPLPDGADSFAGTI
                     LHSLDYRDGSDFAGRRVVVVGLGASAVDIAADLSRHAERTLLSVRRGLHIVPKQVFGMS
                     LDEVAEAPWWNEMPFAERRKWVEQALLVARGRLSDYGLPEPDHPILSSATTVSDEILSR
                     IRHGAVTPKPAIASFEGDRVVFTDGSSETADTVVYCTGFHMTFPFLPPGCPVAADGSVE
                     LYRRIVPADRPGLYFVGLVRPAGALTRLVEAQAQWVARLVDGAAALPGAEEMREEIGTY
                     LTGIAERYGRTRGASIQVDVGPYLAEFREPLPV"
     gene            complement(10001..11128)
                     /locus_tag="APK71_RS32440"
     CDS             complement(10001..11128)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971675.1"
                     /locus_tag="APK71_RS32440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_030403251.1"
                     /sec_met_domain="indole_PTase (E-value: 2.1e-147, bitscore:
                     484.1, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAAPTGTDPQGAPTLGSFTGGQLRRLGSVAGLSRADVETYAQVL
                     TDALGPVAQRPLSLAPPTRSFLSDDHTPVEFSLSFRPGAAPAMRVLVEPGCGATSLADN
                     GRAGLEAVRRMARRWHFTTDALDELLDLFLPPTPQGPLALWCALELRPGGVPGVKVYLN
                     PAAGGEERSAATLREALRRLGHHRAFDTLPQGSGYPFLALDLGDWAEPRAKVYLRHDNL
                     TAGQAGRLSRTDSGPTPTAVEGFFRTAGGLGPDAGGLDGRPVQSCHSFTDLGAARPSGF
                     TLYIPVRDYVRHDGEALARASTVLHHHGMDASVLNRALAALTERRPEDGVGLIAYLALA
                     HQGDRPPRVTAYLSSEAYTVRPPVVETVRQPLSVR"
     gene            complement(11336..12685)
                     /locus_tag="APK71_RS32445"
     CDS             complement(11336..12685)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388030.1"
                     /locus_tag="APK71_RS32445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome P450"
                     /protein_id="WP_055469797.1"
                     /transl_table=11
                     /translation="MNAHDTAPVPPPGCPAHGSGARVPLHGPEFAAHPQAYYEYLRHYG
                     AAAPVELAPGVEATLVTDYAAALQLLQDSGNFRKDARRWRAFNEGRISPDSPVVPLLAH
                     RHNCMFADGADHLRLRQAVTDSMARVDTRRLSRSTEQTSGYLISQFAARGSADLLGDYA
                     KQLPLFVFNELFGCPADIGDRVMFGISGMFDGVNAEKAAAVLFEAVGELVTLKRRKPGD
                     DVASWLMQHEARLDDEETVHQIALLLSAGAEPLRNLLGNTLHRLLTHERYAREGGLIDE
                     ALDDTLWENAPMANFAPHYPAVDTELAGQRMQAGDLVLVSFAAANTGPALQASRQAGSN
                     RAHLAWSAGPHACPSKEPARHITVTAIEHLLNELPDVELAVPEDSLTWRPGPFNRALAN
                     LPARFTPVRAARRGEAGRATVAPGPERPTGPARPAEHKGMWSQFLNWLTR"
     gene            complement(12682..13293)
                     /locus_tag="APK71_RS32450"
     CDS             complement(12682..13293)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971676.1"
                     /locus_tag="APK71_RS32450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_030403253.1"
                     /transl_table=11
                     /translation="MGSAPSLGERDYVREGATQTAVKILVVGHFAVGKTTLIGSISEIE
                     PLSTEETMTQAAEEVDDLKGVRGKTTTTVAMDFGRLTISDRVVLYLFGTPGQQRFVQMW
                     EDMARGALGALVLVDPERLADSFPVIDLIEHYGLDYAIAVNHFDGTPLRDERALREALD
                     LLDDTPVVTCDARDEKSSAAALTTLVRYLLNRTRQELEHP"
     gene            complement(13268..13645)
                     /locus_tag="APK71_RS32455"
     CDS             complement(13268..13645)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971677.1"
                     /locus_tag="APK71_RS32455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_030403254.1"
                     /transl_table=11
                     /translation="MTGHDGWQPEAPELVRPYVITKGRGLPDEDALSLITLVTASADQQ
                     QRPARLSPEEQSLLDLCSAGYLSVAEIAGHTHFPLGVVRILLASLMEGGHLMTRPPVAR
                     ARLADREILEEVLNGLRAKFG"
     misc_feature    complement(13604..13606)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13642..14043)
                     /locus_tag="APK71_RS32460"
     CDS             complement(13642..14043)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971678.1"
                     /locus_tag="APK71_RS32460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_030403255.1"
                     /transl_table=11
                     /translation="MNDDLSWMLDSALEIPGALHAVLISADGLLMARTQDFDKDDADRV
                     AAAMSGVQSLSRTLAFFCEDPSQSWRQTLVEFDGGWVFLISAGEGAYLGVSASPEVDMA
                     DITFRMQQLVAQLGKRLTTPPRENLGSRS"
     gene            complement(14040..15233)
                     /locus_tag="APK71_RS32465"
     CDS             complement(14040..15233)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971679.1"
                     /locus_tag="APK71_RS32465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-binding protein"
                     /protein_id="WP_030403256.1"
                     /transl_table=11
                     /translation="MTEYTGNPLLWVALVALVAAAVLISRQRKAARALRQQVQGLRDHY
                     TELENDYGKSVQAAQERAEDETKTVLKSAMRTLQGLAAEQQLVLSRLQTKYGDSALLQD
                     LLEIDHTNSQFGRRAQSIAVLCDGWLGGRRDTASVYDVVRSAQGRIRHFRRVDILSQVD
                     FGITSRAVEPVALALAELLDNATSYSSPDTVVEINIRTVPKGICVVVDDAGVGMSDEER
                     ARADKLLATERASGVAGLGNPPQFGFAVIGLLCERFGFEVSVDSSSPYGGVRAVVLLPH
                     ELLTAMPEKKAPAPASAPAARGTARPVPEGGPEAALTSSPTGDGLPRRRRKRPMAIVPG
                     SASTPRATGRSDSEQAQVMGAFQRGTQSGRVTEPDSPDHAGRTSETPGASSEGHEVS"
     misc_feature    complement(15422..15436)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.11"
                     /tool="antismash"
     gene            15564..16316
                     /locus_tag="APK71_RS32470"
     CDS             15564..16316
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018104742.1"
                     /locus_tag="APK71_RS32470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="WP_199825971.1"
                     /transl_table=11
                     /translation="MAAVFTAGVGAGAINSVVGSGTLITFPVLLATGLPPVTATVSNAL
                     GLIPGSISGAIGYREELRGQRRRVLKLGSGALVGGLAGASLLLMLPADAFETIVPVLVG
                     LALLLVAFQPQIGRLVQRRRARTGASPRRDGGPLLFGGLTLASVYGGYFTAAQGIIYLS
                     LMGMLLDEPLQRLNGVKNVLAAVVNTVAALFFLFAADFEWTAVGLLAVGSGLGGYVGAK
                     VGRRFSPAVLRTLVVTVGTVALVQLLLR"
     misc_feature    complement(16376..16390)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.86"
                     /tool="antismash"
     gene            16445..17173
                     /locus_tag="APK71_RS32475"
     CDS             16445..17173
                     /EC_number="3.4.21.-"
                     /GO_function="GO:0004252 - serine-type endopeptidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016328090.1"
                     /locus_tag="APK71_RS32475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="trypsin-like serine protease"
                     /protein_id="WP_030403258.1"
                     /transl_table=11
                     /translation="MRTTRLVPALLAALVAALLSALALAPTASAVEPRPGDGGPQPIIG
                     GGYAQNAPWAARLFSNGQQTCTSTIISPTWILTAKHCVSGGNLAFRIGSLDQGSGGTVA
                     NGVQTVTSASADLALVRLDRSVSATYAPLGQPGTVRVGQTVQVYGWGATSRCGSEINCQ
                     SPYLKVANVSVTQGCYDAYYGQAICARPVDGITAGGDSGGPMMAGGVQVGVASTSDRQS
                     TTAYTNVTAYRSWIQSVAGV"
     gene            17381..18220
                     /locus_tag="APK71_RS32480"
     CDS             17381..18220
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971683.1"
                     /locus_tag="APK71_RS32480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_031086660.1"
                     /transl_table=11
                     /translation="MTGQTANSRENEHEAAVLRLQDVCVRRFTTDQSILDAVDWTVRPG
                     EHWALLGANGAGKTTLLRLLGALMHPTTGTVEVLGSRLGRVDVRELRARIGHVNSAQRV
                     PQDLTAHAVVLTGHSGTVQPLWRTYDEEVRLRARDLLTELGVKELADRPYGVCSGGQRA
                     RILIARALMADPALLLLDEPFNALDLPSREDLVEAMHQLAEGRPQLATVTVTHHLEELF
                     PAVSHALLLREGRVLSRGTVDDVLTGPLLTACFGRDITVTRRDGRWSAYSGRRVSGA"
     gene            18474..18638
                     /locus_tag="APK71_RS38575"
     CDS             18474..18638
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="APK71_RS38575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_199825970.1"
                     /transl_table=11
                     /translation="MAGTPEQVADRLQEWFEQGAADGFNVMPPWLTGGFDLFADHVVPL
                     LRPAAEPFS"
     gene            complement(18708..19073)
                     /locus_tag="APK71_RS32485"
     CDS             complement(18708..19073)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971684.1"
                     /locus_tag="APK71_RS32485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transglycosylase family protein"
                     /protein_id="WP_030403260.1"
                     /transl_table=11
                     /translation="MICRRNDRRSDVRGSRGRRIRSAAVTLVAATALGATGQAVAAPSV
                     PLRTDWDAIAACESSGNWQANTGNGYYGGLQFAPSSWAAAGGLEYAPRADLASRAEQIA
                     VAERLARMQGMGAWGCA"
     gene            19287..19778
                     /locus_tag="APK71_RS32490"
     CDS             19287..19778
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971686.1"
                     /locus_tag="APK71_RS32490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5949 family protein"
                     /protein_id="WP_031086662.1"
                     /transl_table=11
                     /translation="MTSISTAPRPLRTADLGTLVIMSWSRDTPDGAVPFLLACSLGDGA
                     GGPEATPAAVEGLLSRSGLAVGGDGVLDGTVLPALPISLLVVPGAAALTMPGVNAQFVP
                     TPQWRAAVDERGYACLIFATRPWPGGETGDAAAVAAFANHEDTLATAAQVVLPVRSLRT
                     "
     gene            complement(19822..20358)
                     /locus_tag="APK71_RS32495"
     CDS             complement(19822..20358)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027: isochorismatase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971687.1"
                     /locus_tag="APK71_RS32495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cysteine hydrolase family protein"
                     /protein_id="WP_030403262.1"
                     /transl_table=11
                     /translation="MGKTALIVIDMINTYDHEDAEFLIPAVESVLPRVTGLLERARRQG
                     VPVIYVNDNFGEWRSHHGEILDKALSGPHSRLVEPLKPDESSLFVVKARHSIFFETPLT
                     YLLHQQGIDRLVLCGQVTEQCVLYSALDAHIRHLQVIVPRDAVAHIHADLADAALRMME
                     RNMGARVCDSGELWT"
     misc_feature    complement(20322..20342)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.55"
                     /tool="antismash"
ORIGIN
        1 ccgcgacgcg ctcccgggtc gcgcagcggc gagagcagta gcggcgctcc gggccactgc
       61 cccggctgat gaagacgtcg gggcaggcac cggacgcgca gaccctgccg ggtgggcgct
      121 ggtggtccca gaggaggacg gccagcgcca tgcaggagga ggccaggaac cactccggcc
      181 acggcgcgtc gtcgtcacgg tcgaggtgcg ggtgccaggg cgtactgccc ccgtgggagg
      241 tcagccggag cgcccccgtg tgcgcgccga ggaggcggtt caggacgtgc gcggcggcgt
      301 cggcggagtc cgccgcgaag acctcccgca gcaggtccgc cgccgcgcgc atcccgtcga
      361 cgtcacgcgg ggtgaggtcg acgggaccgg tctcgccgta ggcccgcagc acttcggcca
      421 ccgcttgggg tgcgggcgcg atgccggtgc cggtgccgga agggccgccc ccgagtgcgt
      481 tcacgagggc ggcggtgcgc cgcgccgtgg tcagtacgga gtgcctggtg gaccagtcgg
      541 cgtcgagagg agaggtcacc ggccgaatgt aacgcatatt gcggagtttt gagttacctc
      601 cgtaacgtct ccccggtgcc aaagggttac tcagtacgct cgtatcttgc cggggcgacg
      661 gcggcgcgcg ccggtgacga gatggcggga ccggcgctgc tgctggccgg gctcgccctc
      721 accggctcgg cggctcacgc gtcgtcgctg ctcgcgggca tcacggtctc cgcggcggtc
      781 ggtgggccgg tgctcggggc cctcctggac cgggcggagc ggccgggtcg cctccttgcc
      841 tgcgcgctgg cgctgtacgc ggtgggactg gccgcggtcc tcgccgggct gggccgtctt
      901 ccgaccgcct ggaccgtggt gctcgcggtg ctcacggggc tgctgggccc ggcgctttcg
      961 ggcggctgga ccgcgcagct cccccgggtg gcggcggacc cccacctgcc cagggccaac
     1021 gcgctggacg cgatgacctt cggcgcggcg agcctggccg gtccggcgct cgccggcggc
     1081 gcggccgagg cgctgggagc ccccaccgcg gtcgtgctcg ccgcggcact ggtcgccgcg
     1141 gccgtgcccg tggcgtggcg gttgccggcc cgcaccggca cgggcccgcg gtcgcggccc
     1201 gcccccgtgg ccggcgccct cgccgccggg ttccgggtca ttctccggcg ccctccgctc
     1261 gcccgggcga ccctcgtctc ggtcgtctgc tgcgccgccc agggcgtgct gacggcctgc
     1321 gtcccgctgc tgggcgcgcg ggttctcggt tcggccggac gcggggccct gctgttctcc
     1381 tgcgcggcgg tctccgcgct ggtggccaac gccgtactgg cacggcaccc gcgtttcgcc
     1441 gcaccggaca cgatcgtgcg ggccgcggca ctggtccagg ccgcggcact ggccctggcc
     1501 gcgacggggg ccgcgacggg ccggccggcc gcgctcccgg tggccgccgt cctcttcggc
     1561 gtcggcgagg gcccgcagct caccgcgctc ttcgcggtac gccaccggga gtcccccgag
     1621 cacctgcgcg gccagatctt caccaccggg gcgagtctca aggtcaccgc gttcgccctg
     1681 ggcgcggccg tcgcgggccc cctggccacg cggtcgctgc ccggcgccct gttggtggcg
     1741 gcgggcacgg cggcggccgc ggcggccgtc ggacgggaaa gggtttgacg tcgtcggcgc
     1801 cgaacggtcg gatggccccc atgagttcag ggcaggggcg ccgggagccg tacgacctcg
     1861 acgagcgcct cgtacggcgg ctggtcgagg ggcagttccc gcggtgggcg gggcttcccc
     1921 tcgtacgcca cccctccgcg ggcacggtca acgccatgtt ccgtctcggc ccggacctgg
     1981 tcgtccggct gcccctgacc gggggcggcg cggcggacgt gacgacggag cggcagtggc
     2041 tgccccggct ggcgcccctg ctgcccaccg ccgttcccga ggtgctcggg gaaggagtgc
     2101 ccgccgaggg ctacccgtgg ccctggtcgg tgtaccggtg gctgcccggg gagcttaccg
     2161 aggccggcgg gctgaccgac cccctctccc tggcgggcga cctggccggg ttcgtcgcgg
     2221 cgatgcggag cgtcaccctg cccggcgcgc cggcggcgta ccgcggtggg ccgctcgcca
     2281 cgctcgacgg gccgacgcgg gccgcgctcg acgccctgcg ggacctgccg gaggagggcg
     2341 tcgactgcga ggcgctgacc gaggtgtggc aggacgcgct gcacgccccc gcctgggacg
     2401 ggccgccccg ctggctgcac gcggacctga tgccgggcaa cctgctggtg accggcggca
     2461 ggctgagcgc ggtgatcgac ttcgggtgca tgggggtggg cgacccggcc tgcgatctct
     2521 tccctgcctg gaacctgctg ccggccggcg cgagggaggt cttccgcgag gcgctgggcg
     2581 tggacgacgc cacctggcgg cgcggccggg gccgcaccct ctcccaggcg ctgatcgccc
     2641 tgccgtacta ccgggagacc aaccccgcga tggccggcaa cgcccgtcac gtgatccggg
     2701 cggtcctggg ggaggcggag cgggtccacc gacccgcgaa gccgccggca cccctcgggg
     2761 ggacggatgt gacgtccggt caactgtcgt agtccaccgt cactttctcg gagaccgggt
     2821 aggactggca ggtcaggacg tagcccgcgt cgacctcggc cgtttcgagc gcgtagttgc
     2881 ggcgcatgtc gacactgccg tcggtgacca gggcccggca ggtgccgcag acgcccccct
     2941 tgcaggcgaa gggcaggtcg gggcgggtct gctgggcgcc gtcgaggatc gagcgctccc
     3001 gggagagcgg ggcggtcgtg gagcgcccgt ccagggtgac ggtgacctcg ctgacggggc
     3061 cctcggggcc gcggtcctcg tggtggacct cccgcacggg ctcgtcgtcg gcgtagaaca
     3121 gctcgcggtg gacgcgctcc gccggaacgc cgaggccggc caggacctgc tgggcgtcgg
     3181 cgaccatgcc ctgcgggccg cacagccacc agtggtccgc gcccgccacg tccaccaggg
     3241 agccgatgag cgccgagagc cgcccggcgt ccagccggcc ggagagcacc tcggcctccc
     3301 ggggttcgcg ggagagcacg tgggcgaggt ggaagcgggt cgggtgcagg tccttcaggt
     3361 cggccagttc gtcggcgaac atcaccgtgt cggtgcggcg gttgccgtag aagagcgtga
     3421 cggtggagcg gtcgtcggcg gcgagcaccg actcggcgat ggagaccatc ggggtgatgc
     3481 ccgaaccggc ggcgatcagg acgtggtggc cgggggtggt caggtcgggc gtgaagaggc
     3541 cggtgggggc catcacctcc acggcgtcgc ccgggcgtac gtcgttgacc agccacgccg
     3601 agaagagccc gcccggcacc acgcggaccc cgatgcgcgg cgccgcaccg gccgccgagc
     3661 agatcgagta cgaacggcgt tcgtcccggc cgtccacctc gcgccgcagc gtgagcgact
     3721 gaccgggtgc gaaggcgaac tcccgggcca gctcgtcggg gatctcgaag ctcacggccg
     3781 cggcgtccgc gcacagccgc tcgacggcgg cgacgcgcag ggtgtggaag gcgggccggc
     3841 ggcgggtgcg caccggggcc gccgggacgg gggcggtcgg ggccatcaga tctccttgac
     3901 gtactcgaac ggctcgcggc aggcccggca gcgccacagc gccttgcatg acgtggcggc
     3961 gaagcgggag gtctcctcgg tgtccgccga gccgcagcgg ggacagcgca ccgccggccg
     4021 ggtgggcgac aggacgaggg ggacggggcc gccgcggggt gcgggcccgg gcggggcgat
     4081 gccgtgctcg gcgagcttca ggcggcccgc ctcggtgatc cagtcgctcg tccagggcgg
     4141 gtccaggacc gtgcggatct ccacgcgcgg gtatcccgcc ccgcgcaggc gcgcggcgac
     4201 gtccgcccgc atctcggcca tggccgggca gcccgagtag gtgggggtga ggctcgcgac
     4261 gacggtgccg tcctcgccga cctcgacgtc gcgcaggacg ccgaggtcgg cgagggtgag
     4321 catgggcagc tcgggatcgg ggacctgctc ggcgacgtgc cgggcgcggc gggcgtccag
     4381 gagtgcgggg ccgtcgctca ccatgtcgcc tccgggtggg cgcgggcgac gccctgcagc
     4441 tcggtcagga gcggcgccag gtgctcggtg tgctcgccgg cgcggcccga gccgggcaac
     4501 gggcggtaca cgggcagggt cagtccggcc gcctcggtga cctggcgcag gtcctcggcg
     4561 acctcgtcgc gcacgtcgta cgccgcgtgc agttcgccga ggtacggggc gacctcgtcc
     4621 agcgcggcgc gcgtccggcg gtgggactcg tccgtgccgt cgcccaggcg cacgcaccac
     4681 tcggcggcgt actgccggtg atacgtcagc tccttgacgc ccttgacggc gaccgccgcg
     4741 agcaccggat cggggtgggc cccgagccgc cggaagtggg ccagccgcca gctggagagc
     4801 accaacagcc gcacgaccgc gaacgcgaag tcgccgcggg ggagttcggc caggcggacg
     4861 ttgcggaagt cagcggcgtc gcggaagtag gcgtaggcgt cctcgtcgcg gccggtgccg
     4921 tccacctgcc cggcgcggga gtacagcagg cgggcctgac cgaggaggtc gaggccgatg
     4981 ttggccagcg ccacctcctc ctccagctcc ggcgcgcggg tgacccactc ggcgagccgc
     5041 tgggcgctca ccagggcgtc gtcggcgagc gccacgcact ccccggccag tgcggcggcg
     5101 tcgacgccct cgggcacggc ggtgtcgacg ccgtgcagcg ggtcctcgaa gccggtgccg
     5161 taggcccagc gggtgtcgtc ctcgtgcccc tcggccaggg tgaggtagac gtggtcgtca
     5221 ctcatgccct gctcctagat gtggggaacg tcgtcgggga tgtcgtagaa ggtcgggtgg
     5281 cggtagacct tgtcggcgct gggggcgaag aaggggtcct tctcgtcgcg ggtggaggcg
     5341 gcgatgtgct cggagcgcac cacccagatg ctcacgccct cgttgcgccg ggtgtagagg
     5401 tcgcgggcgt gggtgagggc catggcgtcg tcggcggcgt gcagcgagcc gacgtggacg
     5461 tggttgagtc cgcgcttgcc gcgcacgaag acctcgtaca gcggccagcc ctgcctgccg
     5521 ggcgtctcgg gggtcatgcc gccgctccct tccgcgcgcg ggcggcctgc ttggcggcgt
     5581 gtgcggtggc cgcctcgcgc acccaggcgc cgtcctcgtg ggcggtccgc cgccgctcca
     5641 tccgccggtc gttgcagggg ccgtcgccct tgatgacgcg catcagctcg tcccagtcgg
     5701 gggtgccgaa gtcgtggtgc ccggtctcct cgttccagcg cagctcgggg tcgggcaggg
     5761 tgacgccgag cttctcggcc tgcgggacgg tcatgtccac aaagcgctgg cgcagctcgt
     5821 cgttgctgtg ccgcttgatc ttccaggcca tcgaccgcgc cgagttgggc gaggcgtcgt
     5881 cgggcgggcc gaacatcatc agggacggcc accaccagcg gttgacggcg tcctggacca
     5941 tctcgcgctg ggcgtcggtg ccgcgcatca tcgtcatcag cagctcgtag ccctgccgct
     6001 ggtggaagga ctcctccttg cagatgcgca ccatcgcgcg cgcgtagggc ccgtacgagc
     6061 tgcggcacag cggcacctgg ttgcagatcg cggcgccgtc cacgaaccag ccgatcacgc
     6121 cgacgtcggc gaagctgagg gtcgggtagt tgaagatcga cgagtacttc tggcggccct
     6181 cgacgagccg ctgggtgagg tcgtcgcggt ccgcgccgag ggtctcggcg gccgagtaca
     6241 ggtacaggcc gtggccggcc tcgtcctgga ccttggcgaa gaggatcgcc ttgcggcgca
     6301 gcgacggggc ccgggtgatc cactcgccct cgggctgcat gccgatgatc tccgagtgcg
     6361 cgtgctgggc gatctgccgg atcagcgtct tgcggtagcc gtcgggcatc cagtcccgcg
     6421 gctcgatgcg ctggtcgcgt gcgatcgtcg cgtcgaagtg ctcctggagt ccgtccggcg
     6481 cgtccggggg cggcgcctcg gcggcgtgtg tcgtggtcat cgtcaccagc ttcccaaccg
     6541 accattcgtt cggtatcagt gtgacgtgtt tccgcctgcc gggcaagacc cggaccccgc
     6601 cggccgcacc cttgacagtg ccaccgcgtg gctggattac ttggccttgc cgcgagctaa
     6661 ccgaatggtc ggtcgggaga caaggtggtg ggtacggtgt cgcaggccac gcagcggacg
     6721 ccgacggagg cgatgttctt cgcggacgag gcctcccggg ggctcgggat cgagctggtg
     6781 gagcacgggg agggaaccgc ggtgctccgc atgaccgtga ccccggcgat ggtgaacgga
     6841 caccggatcg cccacggcgg ctatctgttc ctgctcgccg acaccgcgtt cgcctgcgcc
     6901 tgcaacagcc acggacccgt gacggtcgcg gccggcgccg acatcgtctt cgtcgccccg
     6961 gcgcgcgagg gcgacgtgct cgtggcccgc gccgaggagc gcgcccgcta cggacgcagc
     7021 gggatctacg acgtgagcgt gcgccgcggc ggggagctga tcgcggagtt ccgcggacgc
     7081 agccgcagcg tgcgggagga cacggcgcgc gaggcgccgg gcacgacgac gaaggagtcg
     7141 cgatgagcag cgagccgacg accgggacgg ccccggcatc ccgaccgggc gagcccctcc
     7201 cccacgacct gctcgacgac gccgagcggc tctcccgcga gcagctccgg gagctccagc
     7261 tcgaccgtct gcgcgcgacc ctgcggcacg cctacgacca cgtcgagctg taccgcaaga
     7321 agttcgacgc cgccggggtg acccccgacg actgccgcag cctggcggac ctgtcccgct
     7381 tccccttcac caccaaggca gacctgcggg acacctaccc cttcggcatg ttcgccgtcc
     7441 cgatgtccaa ggtgcggcgg gtgcacgcct ccagcggcac caccggacgt gccacggtcg
     7501 tcgggtacac ggacaacgac ctgtccatgt gggcggacgt catagcccgt tccctgcgcg
     7561 ccgcgggcgg gcgcccgggt cacaaggtgc acatctccta cggctacggc ctgttcaccg
     7621 gcggcctggg agcccactac ggcgccgaac gcgccggctg cacggtgatc cccgcctccg
     7681 ggggcatgac ggcgcgtcag gtgcagatca tccaggactt ccgccccgag atcatcatgg
     7741 tcaccccgtc ctacatgctc accctgctcg acgagttcga gcgccagggc gtcgacccgc
     7801 gcaccagttc cctcaaggtc ggcatcttcg gcgccgagcc gtggaccgag gagatgcggc
     7861 gcgagatcga ggagcgcatg gacatccacg ccgtcgacat ctacggcctg tccgaggtga
     7921 tcggcccggg cgtggcccag gagtgcgtcg agaccaagga cggactgcac atctgggagg
     7981 accacttcta tcccgaggtg gtggacccgc tcacggacgc cgtgctgccc gagggcgagg
     8041 agggcgaggt cgtcttcacc tccctcacca aggaggcgct cccggtgatc cggtaccgca
     8101 cacgggacct gtcccggctg ctgcccggca ccgcgcgccc cgccttccgc cggatgcaga
     8161 aggtcaccgg ccgctgcgac gacatgatca tcctgagggg ggtgaacgtc tttcccaccc
     8221 aggtcgagga ggtcgtgctg cgcaccccgg gcgtcgcccc gcacttccag atccggctca
     8281 ccgagcgcgg ccgcatggac cacatgacgg tgcgggtcga ggcccgcccc gacgccggtc
     8341 ccgagcagcg cgatgccgcc gcgagggcga tcgcgcaggg cgtcaaggac ggggtgggcg
     8401 tcaccgtcga ggtcgaggtc gtcgagccgg agacgctgga gcgctcgctg ggcaagatcc
     8461 gccgggtgtg ggacctgcgg ggcgcgtgaa acgtgagcac ggacacgtgt gttcgtgcgc
     8521 cgtaccggtg tgcgagaagg aacggatggg caggaaaggc atgatcgggg gaggttgagc
     8581 agatcctgag gggacatccc gtgcgtgtgt gtgtgatcgg tgcaggactg tcggggctgg
     8641 cgatgggcca tgccctgaag agccgcggca tctccttcgt ctgcctggag aaggcacgtg
     8701 acgtcggcgg tatctggcga caaccgggcg ccggtgagcg gggaccgggc tatcagaccc
     8761 tgcacctgaa caccgccaag cagctcacgg gttacgcgga cttcccgatg ccgtccgact
     8821 acccgctcta tccccggcac acccaggtcg ccgcctacct gcggtccttc gccgagtggg
     8881 cgggcctgct cgaccacgtg gagctgcgga ccgaggtggt ctccgtccgt caggacgcgg
     8941 acggcgggtg gaccgtcgtc agccgggacg cggagggcgc gcagacctcg cgccggttcg
     9001 agcaggtggt cgtcgcctct ggccaccaca acgagccggc cctgcccgat ccccttccgg
     9061 acggcgccga ctccttcgcc ggaacgattc ttcactccct cgactaccgc gacggcagcg
     9121 acttcgccgg tcggcgcgtc gtcgtggtgg gcctcggcgc ctccgcggtg gacatcgccg
     9181 cggacctctc ccggcacgcg gagcggaccc tgttgtcggt gcgccggggg ctgcacatcg
     9241 tgcccaagca ggtcttcggt atgtccctcg acgaggtcgc cgaagccccg tggtggaacg
     9301 agatgccctt cgccgagcgg cgcaagtggg tggaacaggc cctgctggtg gcccggggca
     9361 ggctctcgga ctacggcctg cccgagcccg accacccgat cctctcctcc gcgacgaccg
     9421 tctcggacga gatcctcagc cggatccggc acggtgcggt gactccgaag cccgcgatcg
     9481 cctcgttcga gggcgaccgg gtcgtgttca cggacggcag ctccgagacc gccgacacgg
     9541 tcgtctactg caccggtttc cacatgacct tccccttcct gccgccgggc tgcccggtcg
     9601 cggccgacgg ctcggtcgag ctctaccggc ggatcgtccc ggccgaccgg cccggtctgt
     9661 acttcgtggg actggtgcgg cccgcgggcg ccctcacccg gctggtggag gcccaggccc
     9721 agtgggtggc gcgcctcgtc gacggcgccg ccgcgctgcc cggggccgag gagatgcgcg
     9781 aggagatcgg cacgtacctg accggcatcg ccgagcgcta cggccggact cgcggcgcct
     9841 cgatccaggt cgacgtgggt ccctacctgg cggagttccg ggagccactg ccggtgtgac
     9901 gtcccggagg acgcggtcgg cgaccacgcc cggccgcgtc cgtgcccacg gctcccggcg
     9961 gatcgcgccg ggagccctgt ctcgcgcgcg gacgttccgt tcagcggacc gacagcggtt
    10021 ggcggacggt ctccacgacc ggcggccgga ccgtgtaggc ctccgaggag aggtacgccg
    10081 tcacccgcgg cgggcggtcc ccttggtggg cgagggccag gtaggcgatc aggccgaccc
    10141 cgtcctcggg ccgccgctcg gtgagtgcgg ccagggcgcg gttgagcacg gaggcgtcca
    10201 tgccgtggtg gtgcagcacc gtggacgccc gtgccagggc ctccccgtca tgccggacgt
    10261 agtcgcgcac cgggatgtac agggtgaatc cactcggccg cgccgcgccg aggtcggtga
    10321 aggagtggca ggactgaaca ggccgcccgt cgagcccacc cgcgtcgggg ccgagacctc
    10381 cggccgtgcg gaagaagccc tcgaccgccg tcggcgtcgg gcccgagtcc gtccgggaca
    10441 gccgtccggc ctggccggcc gtgaggttgt cgtggcgcag gtagaccttc gcccggggtt
    10501 ccgcccagtc cccgaggtcc agggcgagga aggggtatcc gctgccctgg ggaagggtgt
    10561 cgaaggcccg gtggtgcccg agccggcgca gtgcctcgcg cagcgtcgcg gcggaacgtt
    10621 cctccccgcc cgccgccggg ttcaggtaga ccttgacccc gggtacgccg ccgggcctga
    10681 gttccagggc gcaccacagg gcgagggggc cctgcggagt ggggggcagg aacaggtcca
    10741 ggagttcgtc gagggcgtcg gtggtgaagt gccagcgccg cgccatccgg cggaccgcct
    10801 ccagtccggc acggccgttg tcggccaggc tggttgcgcc gcagcccggt tccacgagga
    10861 cccgcatggc cggggccgcc ccgggccgga aggagaggga gaactccacg ggggtgtggt
    10921 cgtcggacag gaaggagcgg gtgggcggcg ccaggctcag cggccgctgg gccaccggtc
    10981 ccagtgcgtc ggtcaggacc tgcgcgtagg tctcgacgtc ggcgcgggag aggccggcga
    11041 ccgagccgag tcttcgcaac tggccgccgg tgaaggagcc gagcgtgggt gcgccctgcg
    11101 ggtccgtgcc cgtcggcgcg gccctcaacg gtccgccccc ggccggggcc gcccaaggcg
    11161 atacccgcct cggggggcgg gtatcagggg attcggcgga gggaaagcgg cgttcgcgga
    11221 tatgtggtcc acgacacctc ctttggctca taagcaactt gaataccgcg ttgctcacta
    11281 cccgtgccgt tcgatcttca tgcggaaggg gcggatggcg agggtgttgc gcacgtcacc
    11341 gtgtgagcca attgaggaac tggctccaca tccccttgtg ttcggccggg cgggccggac
    11401 ccgtcggcct ctccggcccg ggcgccacgg tggcccgccc cgcttcgccg cgccgtgcgg
    11461 cacgcaccgg ggtgaaccgg gccggaaggt tggccagagc gcggttgaag gggcccggac
    11521 gccacgtcag gctgtcctcg ggaacggcga gttcgacgtc gggcagttcg ttgagcaggt
    11581 gctcgatggc cgtgaccgtg atgtgccggg ccggttcctt ggacgggcac gcgtgcgggc
    11641 ccgcgctcca ggcgaggtgc gcgcggttgc tgcccgcctg gcgggacgcc tggagggcgg
    11701 gaccggtgtt ggcggcggcg aagctgacga gcacgaggtc gcccgcctgc atccgctgtc
    11761 cggccagttc cgtgtcgacc gccgggtagt gcggggcgaa gttggccatg ggcgcgttct
    11821 cccacagcgt gtcgtcgagc gcctcgtcga tcaggccgcc ctcacgggcg taccgctcgt
    11881 gggtcaggag ccggtgcagg gtgttgccga ggaggttgcg caggggttcg gctcccgcgc
    11941 tgagcagcag ggcgatctgg tggaccgtct cctcgtcgtc gagtcgggcc tcgtgctgca
    12001 tcagccagga ggcgacgtcg tcgccgggct tgcgccgctt cagcgtgacg agctccccca
    12061 cggcctcgaa gagcaccgcg gcggccttct cggcgttgac gccgtcgaac atgccggaga
    12121 tgccgaacat cacccggtca ccgatgtcgg cggggcagcc gaagagttcg ttgaagacga
    12181 acagcggaag ctgcttggcg tagtccccga gcaggtcggc cgaaccgcgg gcggcgaact
    12241 gggagatgag gtagcccgag gtctgctcgg tgctgcggct cagccgccgg gtgtccaccc
    12301 gtgccatgct gtccgtgacc gcctgacgca gcctgaggtg gtcggcgccg tcggcgaaca
    12361 tgcagttgtg ccggtgggcc agcagcggca cgaccgggct gtccgggctg atcctgccct
    12421 cgttgaaggc ccgccagcgg cgcgcgtcct tgcggaaatt gccggagtcc tgcagcagtt
    12481 ggagcgccgc cgcgtagtcc gtgaccaggg tcgcctcgac ccccggggcc agttcgacgg
    12541 gggccgcggc gccgtagtgg cgcaggtact cgtagtacgc ctgcgggtgg gcggcgaact
    12601 ccggtccgtg cagcggcaca cgggcgccgg agccgtgggc cgggcagccg ggcggcggta
    12661 ccggcgcggt gtcgtgggcg ttcatgggtg ctccagctcc tggcgggtgc ggttcagcaa
    12721 gtagcggacg agggtggtca gtgcggcggc cgaggacttc tcgtcgcggg cgtcgcaggt
    12781 gacgacgggg gtgtcgtcga gcaggtcgag tgcctcgcgc agcgcccgct cgtcgcgcaa
    12841 cggcgtgccg tcgaagtggt tgacggcgat ggcgtagtcg agcccgtagt gctcgatgag
    12901 gtcgatcacg gggaaggagt ccgccagccg ctccgggtcg accagcacca gggcgccgag
    12961 cgcaccgcgg gccatgtcct cccacatttg cacgaagcgc tgctggccgg gggtgccgaa
    13021 gaggtagagc acgacgcggt cgctgatggt caggcggccg aagtccatgg cgaccgtggt
    13081 ggtggtcttg ccccgcacgc ccttgaggtc gtcgacctcc tcggcggcct gcgtcatcgt
    13141 ctcctcggtg gacagcggct cgatctcgga gatcgagccg atgagggtgg tcttgcccac
    13201 cgcgaagtgc ccgacgacga ggatcttgac cgccgtctgg gtcgctccct cgcgtacgta
    13261 gtcccgctca cccaaacttg gcgcggagcc cattgagcac ctcctccagg atctctcggt
    13321 ccgcgaggcg ggcgcgggcc accggcgggc gggtcatgag gtgaccgccc tccatcaggg
    13381 aggccagcag gatccgcacg acgcccagcg ggaagtgggt gtgtccggcg atctcggcga
    13441 ccgagaggta gccggcggag cagaggtcga gcaggctctg ctcctcgggg gacagccggg
    13501 ccggccgctg ctgctggtcg gcggaggccg tgaccagggt gatgagggag agggcgtcct
    13561 cgtcgggaag tccgcggccc ttggtgatga cgtacggacg tactaattcc ggcgcctcgg
    13621 gctgccagcc gtcgtggccg gtcacgagcg gctgcccagg ttctcgcgcg gcggtgtcgt
    13681 cagccgcttg ccgagctggg cgacgagctg ctgcatccgg aaggtgatgt cggccatgtc
    13741 gacctccggg gaggcggaga caccgaggta ggcgccctcg ccggcggaga tcaggaagac
    13801 ccagccgccg tcgaactcga ccagggtctg ccgccaggac tggctggggt cctcacagaa
    13861 gaaggcgagg gtgcggctga gcgactgcac accgctcatc gccgcggcga cccggtcggc
    13921 gtcgtccttg tcgaagtcct gcgtccgggc catcagcagg ccgtcggcgg atatcaggac
    13981 cgcgtgcagg gcgcccggaa tctccagcgc gctgtcgagc atccatgaca gatcgtcgtt
    14041 cacgagacct catgtccttc gctgcttgca ccaggtgttt cgctcgtccg gccggcgtgg
    14101 tccgggctgt ccggctcggt gacccggccg gactgcgttc cgcgctggaa ggcacccatg
    14161 acctgtgcct gctcggagtc ggagcggccc gtcgcgcgcg gggtggacgc gctgccgggc
    14221 acgatggcca tcggccgctt gcggcggcgc cggggcagac cgtcgccggt cggggaggag
    14281 gtgagtgccg cctccggtcc gccttcggga accgggcggg ccgtaccgcg ggcggccggg
    14341 gcggatgcgg gggcgggggc cttcttctcc ggcatggcgg tgagcagttc gtgcgggagc
    14401 aggaccaccg cccgtacacc tccgtagggg gaggaggagt ccaccgacac ctcgaaaccg
    14461 aatcgttcgc acagcaggcc gatgacggcg aagccgaact ggggcgggtt gccgagcccc
    14521 gccacgcccg aggcgcgctc ggtggcgagc agcttgtcgg cgcgggcccg ctcctcgtcg
    14581 ctcatgccga caccggcgtc gtccacgacc acgcagatgc ccttgggcac cgtccggatg
    14641 ttgatctcga cgacggtgtc cgggctggag tagctggtgg cgttgtcgag cagctcggcg
    14701 agggccaggg cgacgggctc gacggcccgg ctggtgatgc cgaagtcgac ctgggagagg
    14761 atgtccaccc ggcggaagtg ccggatgcgc ccctgggcac tgcgcaccac gtcgtacacg
    14821 gaggcggtgt cgcgccgccc gccgagccag ccgtcgcaca gcacggcgat ggactgggcg
    14881 cgccggccga actgcgagtt ggtgtggtcg atctccagca ggtcctggag cagggccgag
    14941 tcgccgtact tggtctgcag ccgggagagc accagctgct gttcggcggc gaggccctga
    15001 agggtccgca tggcggattt cagcaccgtc ttcgtctcgt cctcggcccg ctcctgggcg
    15061 gcctgcacgg acttgccgta atcgttctcc agctcggtgt agtgatccct gagcccctgg
    15121 acctgctgcc gcaacgcccg tgccgccttg cgctggcggc tgatgagcac ggcggcggcg
    15181 acgagggcga cgagggcgac ccagagcaag gggttccctg tgtattccgt cataagactc
    15241 tcttcaggcg actgacagcc ggcttgctga attccgtccg tgcgggcggt ccggtggact
    15301 gcccgcaccg gggaagctgc ccgggctgcc ccttgtgtcg gggatgccgt ctttcaccca
    15361 tccgcccgct ccgcaaacgc ggtgatcgta tcaccgcatg atcaggtgaa ttgacgtcaa
    15421 gaagcttctg aacatgaacg gttgagaccg gcgagcccgc ccctccgcgc ggtgggtaca
    15481 gtcggccccg tgaaagatgc acaagacacg ttccggccga ctacgggtcc ggggccgggc
    15541 ggtacggggt gacaccggag gccatggcgg cggtgttcac ggccggcgtc ggggccggcg
    15601 ccatcaacag cgtcgtcggc tccggcaccc tgatcacctt tcccgtgctg ctggccacgg
    15661 gactgccgcc ggtcaccgcg acggtctcca acgcgctcgg cctcataccc ggctccatca
    15721 gcggggccat cggctaccgc gaggaactcc gcggccagcg ccggcgcgtg ctgaagctgg
    15781 gctcgggagc gctggtgggc ggtctcgcgg gcgcctcgct cctgctgatg ctgccggccg
    15841 acgccttcga gacgatcgtg ccggtcctgg tgggcctcgc cctgctgctg gtggcgttcc
    15901 agccgcagat cggcaggctg gtccagcgcc gccgggcccg caccggcgcc tcgccccgcc
    15961 gggacggcgg cccgctcctg ttcggcggcc tgacgctggc cagcgtctac ggcggctact
    16021 tcaccgcggc ccaggggatc atctacctgt ccctgatggg catgctcctg gacgagcccc
    16081 tgcaacgcct caacggcgtg aagaacgtcc tggccgccgt cgtcaacacc gtcgccgcgc
    16141 tcttcttcct cttcgccgcg gacttcgagt ggaccgccgt cgggctcctc gcggtcggct
    16201 cgggactcgg cggctacgtc ggcgccaagg tgggccgccg cttcagcccg gcggtcctgc
    16261 ggacactggt cgtgacggtc ggcacggtcg ccctcgttca actgctgctg cgctaggcgg
    16321 cgtccggcat aacgccgcgt tatgcgaagc cgggattgtt cggccggcca ccgggcccga
    16381 catgctgtgg gcgcccccac acaccagcac gcgccccggc gcgtgtcgtc ggaatcgagg
    16441 agccttgcga acaacgagac tcgtccccgc cctgctggcc gccctcgtgg ccgcgctgct
    16501 gtccgccctc gcgctcgccc cgaccgcctc cgcggtggag ccacggcccg gtgacggcgg
    16561 cccccagccg atcatcggcg gcggctacgc gcagaacgcc ccctgggcgg cgcggctgtt
    16621 ctccaacggc cagcagacct gtacctcgac catcatctcc cccacctgga tcctcaccgc
    16681 caagcactgc gtcagcggcg gcaacctcgc cttccgcatc ggcagtctcg accagggctc
    16741 cggcggcacg gtggccaacg gcgtgcagac cgtcaccagc gcctcggcgg acctcgcgct
    16801 ggtccggctc gaccgctccg tctccgccac ctacgccccg ctcggccagc cgggcacggt
    16861 gcgggtcggc cagaccgtgc aggtctacgg ctggggcgcg acctcccggt gcggctcgga
    16921 gatcaactgc cagtccccgt acctcaaggt cgccaacgtg agcgtcaccc agggctgcta
    16981 cgacgcctac tacggccagg cgatatgcgc ccgccccgtc gacggcatca ccgcgggcgg
    17041 cgactccggc ggaccgatga tggccggcgg cgtccaggtc ggcgtcgcct cgaccagcga
    17101 ccggcagagc accacggcgt acaccaacgt gaccgcctac cgctcctgga tccagtcggt
    17161 ggccggcgtc tgacgcctcc cgctccaggg gtcccgtgcc cgcctccgcc accgcggagc
    17221 cgggcgcggg gccccgcccc cctcccggac acccccgcgg cccgggccac ccgcccgccg
    17281 ggccgtccag gaagcggacg gcccggcggg cgggtggccg gtacatctag tgtgcacggt
    17341 gaccgaccac ggggtgtccc gcgtgcgaag gagccacggc atgaccggcc agacagccaa
    17401 ctcccgggag aacgagcacg aggcggccgt gctgcggctc caggacgtgt gtgtgcgccg
    17461 cttcaccacg gaccagtcga tcctcgacgc cgtcgactgg acggtccggc cgggcgagca
    17521 ctgggcgctg ctgggggcca acggcgccgg gaagaccacc ttgctgcgcc tgctcggcgc
    17581 gctcatgcat cccaccacgg gcacggtcga ggtcctcggc agccggctgg gccgggtgga
    17641 cgtccgtgag ctgcgggccc gcatcggcca cgtgaactcc gcccagcggg tgccgcagga
    17701 cctcaccgcc cacgcggtcg tgctcaccgg ccacagcggc accgtgcagc ccctgtggcg
    17761 gacgtacgac gaggaggtgc ggctgcgcgc ccgcgacctc ctgaccgagc tcggcgtcaa
    17821 ggagctggcc gaccggccct acggtgtctg ctccggcggg cagcgggcgc ggatcctgat
    17881 cgcgcgggcg ctgatggccg atccggccct gctgctgctg gacgagccgt tcaacgccct
    17941 ggacctgccc tcccgcgagg acctcgtcga ggcgatgcac caattggccg agggcaggcc
    18001 gcagttggcc accgtgacgg tcacccatca tctggaggag ctgttccccg ccgtcagcca
    18061 cgccctgctg ctgcgcgagg gccgggtcct gtcccggggc acggtggacg acgttctcac
    18121 cggccccctg ctgaccgcct gtttcggccg ggacatcacg gtgacccggc gcgacggccg
    18181 ctggtcggcc tattcgggcc ggcgcgtttc cggagcatga cgggcccgcg aaggcgtcgt
    18241 tgcggtcccg gcggcgcccg ccggcagacc tggcggaagg gcgaggaggg ccggaaagga
    18301 gaggcgccgg aatccgggca tgcgtgtgcg cgaggtcatg accccgggct cccgcatcgg
    18361 atcactcgcg gaacgacagc cgcttccggc tggtcctgga catcgtcgac cgcgaacggc
    18421 ccagcgtccg ccaaccgctg caccgcctca cgggcgcccg cggtcaccgg gtggtggcgg
    18481 gcacgcccga gcaggtcgcc gaccggctcc aggagtggtt cgagcagggg gcggccgacg
    18541 gcttcaatgt catgccgccc tggctgaccg gtggcttcga cctcttcgcc gaccatgtgg
    18601 tgccgctcct gcggccggcc gcggaaccct tcagctgagg gcgacggagg ccgcacgtgc
    18661 acgcccacgg ggtgccccgg tcggcgtggc gcggacggcg gttgcggtca ggcgcagccc
    18721 caggcgccca tcccctgcat ccgcgccagg cgttcggcca cggcgatctg ctcggcgcgg
    18781 ctggcgaggt ccgcgcgcgg ggcgtactcg aggccgccgg ccgcggccca gctcgacggc
    18841 gcgaactgca gtccgccgta gtagccgttg ccggtgttcg cctgccagtt gccgctggac
    18901 tcgcaggcgg cgatggcgtc ccagtcggtg cgcaggggca ccgacggcgc ggccacggcc
    18961 tggccggtcg cgccgagggc ggtggcggcg accagggtca ccgcggcgga gcggatcctg
    19021 cggccacgcg aaccgcgcac gtcgctccga cgatcatttc gtctacagat cataagatca
    19081 ctgctacacc aggtgaccgt ggaccgccgc tcaacaccgc cccgtcttgg tccagtcggc
    19141 gcacgcactc acccctgtcc cccactccgc cgcgtgaggg cgaccggtcg gtacacgccc
    19201 ctcgttcgtg tgaagaaccg cgaaggtgtc gtccagtcgg gtgacggccg ggcgggtgcg
    19261 cgcccacgcc cgcttacggt ttcgcggtga cctcgatctc cactgccccg cgccccctgc
    19321 gaaccgccga cctcggaacg ctcgtcatca tgtcctggag ccgtgacacg cccgacggcg
    19381 ccgtcccctt ccttctcgcc tgctccctcg gcgacggggc gggcggcccc gaggcgaccc
    19441 cggccgccgt cgagggactg ctcagccgtt ccggtctcgc cgtgggcggc gacggcgtcc
    19501 tcgacggcac cgtcctgccc gccctgccga tcagcctgct ggtcgtaccg ggtgcggcgg
    19561 cgctgaccat gccgggcgtc aacgcccagt tcgtccccac cccgcagtgg cgggcggcgg
    19621 tggacgaacg ggggtacgcc tgcctcatct tcgccacccg tccctggccc gggggcgaga
    19681 cgggcgacgc cgcggcggtc gccgccttcg ccaaccacga ggacacgctc gccaccgccg
    19741 cgcaggtcgt cctgccggtg cgcagcctgc ggacctgacg ggcgggcgcc cggtccgccc
    19801 accgcgtggc ggcgggtcgt ctcacgtcca caactcgccg ctgtcgcaca cccgggcgcc
    19861 catgttccgc tccatcatgc gcagcgccgc gtccgcgaga tcggcgtgga tgtgggcgac
    19921 cgcgtcgcgc ggcacgatga cctgcagatg gcggatgtgc gcgtcgaggg ccgagtagag
    19981 cacgcactgc tcggtcacct gcccgcacag gaccagccgg tcgattccct gctggtggag
    20041 cagataggtc agtggggtct cgaagaagat cgagtggcgt gccttgacca cgaagagcga
    20101 ggactcgtcc ggtttcagcg gctcgacgag ccgggagtgc ggtcccgaga gggccttgtc
    20161 gaggatctcg ccgtggtgcg agcgccactc cccgaagttg tcgttgacgt agatcacggg
    20221 aacgccctgc cgtcgcgccc gctccagcag gccggtcacc cgcggcagta cggattccac
    20281 ggcggggatc aggaactcgg cgtcctcgtg gtcgtaggtg ttgatcatgt cgatgacgat
    20341 cagcgcggtc ttgcccatac cgcccaggtt gccaccgcgg ggcgcggaat ccccgctcca
    20401 cccgccgacc gcgggcgggc gagccgcccg gctcaccacg acgcccggcc gaggggcccc
    20461 gccccgtccc gctcgggcgg gagcggctcc cagggtgcgg gtccgccgcc ctcgcaccag
    20521 tcgcgcagcc accgcccgtc cacgcagact atgccgcact gctcggcgta gtcggcggcc
    20581 ggtgcggtga acccggtgct ggcgacgagg accgccacgt cggccccgtg cacggtgaag
    20641 caggtgccgc cgaagcgctg gaggtcctgg gagccgacct tgtggtccgg gctgtagcgc
    20701 ttgcactgga tgacgagccg ccggccgtcg ggcgccaccg ccagcacgtc ggcgccgagg
    20761 tcgcccgccc cgcccacgac ctcgacgtcg acgcagccgt cccgccggca caggtcggct
    20821 atcgcctcct cgaactcgtc cgggtcgagc tcctcgtggc cggcggggac gacggccacg
    20881 gtggtctcct caccgcttgc gtacggtgcg ggtgccggcg ccgcctcacg gtcctcctcc
    20941 agcgcgtcca gcgtcgtcgc cgtggccgcc gccagggcgt ccgtggtgcg cagggccgcc
    21001 cgggccgcgg tgggccggcc gcgtgcgcga cgacgcagga ggacggccgt gaccgcgccg
    21061 agcaccagga cgaacaccca gaccggtcgc cgctgcgccg cgtcgcacgc catgcgcacg
    21121 acccatcc
//
