LOCUS       NZ_BBOK01000011        22742 bp    DNA     linear   CON 17-AUG-2024
DEFINITION  Streptomyces sp. NBRC 110030, whole genome shotgun sequence.
ACCESSION   NZ_BBOK01000011
VERSION     NZ_BBOK01000011.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. NBRC 110030
  ORGANISM  Streptomyces sp. NBRC 110030
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Katano-Makiyama,Y., Hosoyama,A., Hashimoto,M., Tsuchikane,K.,
            Uohara,A., Kitahashi,Y., Ohji,S., Ichikawa,N., Kimura,A.,
            Yamazoe,A., Komaki,H., Igarashi,Y. and Fujita,N.
  TITLE     Whole genome shotgun sequence of Streptomyces sp. NBRC 110030
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 657429)
  AUTHORS   Hosoyama,A., Kimura,A., Ohji,S., Ichikawa,N., Yamazoe,A. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2014) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 97x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina HiSeq 1000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001417675.1-RS_2024_08_17
            Annotation Date                   :: 08/17/2024 02:44:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,240
            CDSs (total)                      :: 7,152
            Genes (coding)                    :: 7,019
            CDSs (with protein)               :: 7,019
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 4, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 45 of 133
            Pseudo Genes (incomplete)         :: 107 of 133
            Pseudo Genes (internal stop)      :: 8 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:33:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 312631
            Orig. end                         :: 335373
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBOK01000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22742
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22742
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22742
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12742](+)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12742
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(93..107)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.84"
                     /tool="antismash"
     misc_feature    276..290
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.8"
                     /tool="antismash"
     misc_feature    320..335
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.88"
                     /tool="antismash"
     misc_feature    320..336
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 14.77"
                     /tool="antismash"
     gene            436..1362
                     /locus_tag="APK71_RS25490"
     CDS             436..1362
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031087.1"
                     /locus_tag="APK71_RS25490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="AraC family transcriptional regulator"
                     /protein_id="WP_030404005.1"
                     /transl_table=11
                     /translation="MADEHHQDGEGGRGADGGSGEGIRTFPFPVDLSLLGVGMQVGPMG
                     AGRTWHAHAPLHRVHRIDFHTVMLFTGGPVRHMIDFAEYEASAGDLLWIRPGQVHRFAP
                     EGEYRGTVLTMQPGFLPRATVEATGLYRYDLPPLLHPDEARLAGLTAALGQLRREYEDA
                     TTLPLSLHTAVLRHTLSAFLLRLAHLAAGSAREGRTDAPGDSTFTLFRDAVERGFATNH
                     SVSAYADALGYSRRTLVRAVRAATGETPKGFIDKRVVLEAKRLLAHTDLPIGRVGAAVG
                     FPDAANFSKFFQQHTDQTPAAFRAELR"
     gene            complement(1511..2911)
                     /locus_tag="APK71_RS25495"
     CDS             complement(1511..2911)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031088.1"
                     /locus_tag="APK71_RS25495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 16 protein"
                     /protein_id="WP_030404006.1"
                     /transl_table=11
                     /translation="MSQTSGNPPRRRPLRRALVAVVGTLGLAAAATAVTGPSAGAAAPP
                     PPSGWTQVFADDFDGAAGSGVNTANWQYDTGTSYPGGPANWGTGEIETMTSSPSNVSLD
                     GSGNLRITPQRDGAGNWTSGRIETKRADFAPPAGGKLRVEARIQVPNVTGAAAKGYWPA
                     FWMLGAPYRGNYWNWPGVGEIDIMENTQGLNTVWSTLHCGTSPGGPCNETSGIGGNAPC
                     PGTTCQAGFHTYRVEWDRSTSVEEMRFSVDGTTFHTVRANQVDATTWANATNHGYFVIL
                     NVAMGGGFPDAFGGGPDGGTQPGHSMLVDYVQVLSAGGSGTTPPPTGGDRDAYGTIEAE
                     SYDAQSGTLTESTSDSGGGRNLGALANGDWAQYKGVKFGSSPATQFKARVASGAAAGVS
                     GLVEVRLDSRTSTPIGSFAVGNTGGWQSWRTIPANISSVTGTHDVYLTFTSGQGADFVN
                     VNWFGFGH"
     misc_feature    complement(2984..2998)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 27.13"
                     /tool="antismash"
     misc_feature    2985..2999
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.03"
                     /tool="antismash"
     gene            3293..4630
                     /locus_tag="APK71_RS25505"
     CDS             3293..4630
                     /EC_number="3.2.1.86"
                     /GO_function="GO:0008706 - 6-phospho-beta-glucosidase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019058990.1"
                     /locus_tag="APK71_RS25505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="WP_055469248.1"
                     /transl_table=11
                     /translation="MRLTMLGGGGFRVPLVYGALLGDRAEGRVTEVVLHDTDAARLAAV
                     TRVLAEQAADVPDAPAVTATTDLDEALRGADFVFSAIRVGGLQGRADDERVALAEGVLG
                     QETVGAGGIAYGLRTVPVAVDIARRVARLAPDAWVINFTNPAGLVTEAMSRHLGDRVVG
                     ICDSPVGLGRRVARVLGADPGRAFVDYVGLNHLGWLRGLRVEGRDELPRLLADPDLLGS
                     FEEGRLFGPEWLRSLGAIPNEYLHYYYFNRETVRAYQEAELTRGAFLRDQQARFYDEMR
                     RPDAPALATWDRTRAEREATYMAENRETAGAGEREAEDLSGGYEQVALALMRAVARDER
                     TTLILNVRNRGTLSVLDGDAVIEVPCLVDANGAHPMAVDPLPDHATGLVCAVKAVERDV
                     LTAAGTGSRAAAVRAFALHPLVDSVDVARRLVDGYLAVHPGLAYLR"
     gene            complement(4623..5759)
                     /locus_tag="APK71_RS25510"
     CDS             complement(4623..5759)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031094.1"
                     /locus_tag="APK71_RS25510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="WP_055469249.1"
                     /transl_table=11
                     /translation="MASPVRVWLNRTYAENVFFMDQLRRNPADRAVEIHATHGDPDSPV
                     LAAADTADLEPEGLSPAGYVEFALAQCARRGIDVFVPRLHQAAIVAHRAEFEAAGTALL
                     APSPEAVALFGDKVTAYEAVRAIGVPVPPWWRVRTAEELVLAVEELEDGGHRACFKPAS
                     GAGGVGFRMVTRDPFSLAHLNGFPSPSVPLPLVLQALRAAEEPVDWLVMPRLEQPEVSV
                     DCLTGPDNRVRLAVGRTKNGRRRGFTLHERWLAPARLIAEAFGLHHLSNVQFRMYGDRP
                     VLMDVNTRPAGGLHQLALCGLNVPWAAVRLALGDDPGELEPPFLGQDYAVVSGPRPLLP
                     PSLPHRLPDLPAPVPSPEPARPAATAQAPATSAPAGLT"
     misc_feature    complement(6004..6020)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 15.95"
                     /tool="antismash"
     gene            6067..6954
                     /locus_tag="APK71_RS25520"
     CDS             6067..6954
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031095.1"
                     /locus_tag="APK71_RS25520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="metallophosphoesterase"
                     /protein_id="WP_031086498.1"
                     /transl_table=11
                     /translation="MTSRAAAAGRVWAVSDLHIGYPENRALVERMRPESGDDWLLVAGD
                     VAETVADVRWALETLADRFGRVVWVPGNHELWTHPRDPVALRGVARYEHLVAMCRELGV
                     TTPEDPYPLWEGEGGPAVVAPLFLLYDYSFLPPGCATKAEGLEYAHGTGIVCSDEYLLH
                     PDPYPSREAWCRARVAETERRLAAIPADLPVIPVNHYPLHRHPTDILWYPEFAQWCGTS
                     LTADWHRRFRVETMVYGHLHIPRTTWHEGVRFEEVSVGYPREWRKRPGPPGRLRRILPS
                     RAASEAPTSPEVTR"
     gene            6951..7631
                     /locus_tag="APK71_RS25525"
     CDS             6951..7631
                     /NRPS_PKS="Domain: ACPS (103-167). E-value: 6.9e-21. Score:
                     66.5. Matches aSDomain:
                     nrpspksdomains_APK71_RS25525_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1060: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020135528.1"
                     /locus_tag="APK71_RS25525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="WP_031086499.1"
                     /transl_table=11
                     /translation="MIEELLPDPVVAVEAFGGDDAGHLPLFPEEEEFVARAVAKRRREF
                     TVVRSCARRAMEKLGVPPQAVPTGERGAPRWPAGLTGSMTHCDGYGAAALVRLTDLASL
                     GIDAEPDGPLPDGVLEAIALPAEAARLRRLGEARPGVHWDRLLFSAKESVYKAWFPLTG
                     QWLDFSEADIEIRADPADPCRGTLHAALLVPGPTVGGRRLARFEGRWAARNGLVATAVA
                     VPYP"
     aSDomain        7260..7451
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS25525_ACPS.1"
                     /evalue="6.90E-21"
                     /label="APK71_RS25525_ACPS.1"
                     /locus_tag="APK71_RS25525"
                     /protein_end="167"
                     /protein_start="103"
                     /score="66.5"
                     /tool="antismash"
                     /translation="LGIDAEPDGPLPDGVLEAIALPAEAARLRRLGEARPGVHWDRLLF
                     SAKESVYKAWFPLTGQWLD"
     gene            complement(7657..7893)
                     /locus_tag="APK71_RS25530"
     CDS             complement(7657..7893)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972321.1"
                     /locus_tag="APK71_RS25530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_030404012.1"
                     /transl_table=11
                     /translation="MTTAVLTDRERGAVQAYLRLLHTVRAGLDTGPGPGAPPGPPLVPP
                     SVLAEAEQALAAAGLAGNEEAFFRLLREWCPRT"
     gene            complement(8087..8740)
                     /locus_tag="APK71_RS25535"
     CDS             complement(8087..8740)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042996.1"
                     /locus_tag="APK71_RS25535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_055469250.1"
                     /transl_table=11
                     /translation="MTGGFEGPGAMPATTLTAVVARVGALADRLGVPHTEVFDVSRLSV
                     ASGVPEPVVGALLGGRPAGEPDVQTRFVQRLDLLRRTRLKPNGRKYTQQEIADGAGMSR
                     QQAGALINGDRRPTMEHCDAIQRFFRVHAGFLTAEDPEALAGALQRTEQELLQQLADRE
                     REAAADEDPLERLLQDHGVRGIAWRAAQLPTDQHRDKVAEWLDMLLESVQRPEP"
     misc_feature    8769..8784
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.07"
                     /tool="antismash"
     misc_feature    complement(8769..8786)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.4"
                     /tool="antismash"
     gene            8974..9633
                     /locus_tag="APK71_RS25540"
     CDS             8974..9633
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069850.1"
                     /locus_tag="APK71_RS25540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_030404014.1"
                     /transl_table=11
                     /translation="MAFQAGGQRPAPRPGPATPEAQAYLQDYTALLESVPHPSLVVDHR
                     WDVVLANGAFRTLFQGAGPHPTAMPDDNFLRFVLFHPDAATVLGEHESSWCLPMLAHFA
                     ATLERYGHDPGLQAVRRDIAQDPFMEAAYRQGLPHWIRTVGARAVEHDGAVRPLHHPDP
                     RRGTTECRVVVETPGALRQLGYTRLTLVLREPRRAAHRSSAVRRAASHLRVVPAAE"
     misc_feature    9892..9909
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.66"
                     /tool="antismash"
     misc_feature    complement(9923..9935)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.5"
                     /tool="antismash"
     misc_feature    complement(9948..9961)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.42"
                     /tool="antismash"
     misc_feature    complement(9957..9969)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            10001..12742
                     /gene="lanKC"
                     /locus_tag="APK71_RS25545"
     CDS             10001..12742
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006130295.1"
                     /locus_tag="APK71_RS25545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_055469354.1"
                     /sec_met_domain="micKC (E-value: 6.4e-234, bitscore: 773.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.6e-11, bitscore: 39.0,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKGYAVYCDADPYFYDAPHRAADRTGTSRPRYAAASSPVPRGWR
                     RNESGDWLALRPAGARLPDQGWKIHVSACLDNAESVLDRVWRHCVAGGTAFKFVPGRHL
                     LHQRNAKYADRAGSGKFVTVYPADEADFERLVGELSDLLAGEPGPHILSDLRIGDGPVH
                     VRYGGFTRRDCYDADGELRPAVARPDGVLVPDPRGPVFRVPDWVVPPAFLGPHLDARSA
                     VTVTGMPYAVESALHFSNGGGVYLARDTRTGERVVLKEARPHAGLAADGADAVTRLHRE
                     RRALERLSGLDCTPEVLDHLTVGDHHFLVLEHIDGKPLNTFFARRHPLIEADPGERRLA
                     EYTAWALDVHARVERAVEAVHARGVVFNDLHLFNIMVRGDDTVALLDFEAAHPVDEAGR
                     QTVANPGFVAPSDRRGVAVDRYALACLRLALFLPLTSLLAVDRNKAAHLADVVAEQFPV
                     DRAFLDEAVDEITRAGGAPTAGPGARATLSRPNGAGTPGAAGTGEPRSAGPVVRRAHGP
                     VVPVRPDDWPRSRDSMAEAIRASATPSRTDRLFPGDIAQFATAGGGLSFAHGAAGVLYA
                     LAESGAGRDEGGEQWLLERTGRPPSGTPLGFHDGLAGIAWTLERLGHRDRALGLTELLL
                     DQPLDHLGPDLHSGTAGLGLALDSLAGSTGETAPHAAALRCAERAADGAPADRAGRGRA
                     RAGLLYGGAGRALLFLRLFARTRDTALLDLARDALRQDLARCVRGAGGALQVDEGWRTM
                     PYLGAGSVGIGMVLDDYLAHRADEEFARARNEIVAAAQAMFYAQPGLYRGVAGMVLYLG
                     RTTAAVPGTGPAAVRRQLDALSWHALSYRGRLAFPGEQMMRLSMDLSTGTAGCLLAVAS
                     VLGDAPVGLPFLPPLRRSGAPGPGPTRGREKAHPLPNERKSS"
     gene            12739..12867
                     /locus_tag="APK71_RS25550"
     CDS             12739..12867
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018849360.1"
                     /locus_tag="APK71_RS25550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_003972313.1"
                     /transl_table=11
                     /translation="MNLFDLQSMETPKEEAMGDVETGSRASLLLCGDSSLSITTCN"
     CDS_motif       12739..12801
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MNLFDLQSMETPKEEAMGDVE"
                     /locus_tag="APK71_RS25550_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       12802..12867
                     /prepeptide="core"
                     /locus_tag="APK71_RS25550_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="32.20"
                     /molecular_weight="1955.2"
                     /monoisotopic_mass="1954.0"
                     /core_sequence="TGSRASLLLCGDSSLSITTCN"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MNLFDLQSMETPKEEAMGDVE"
                     /leader_location="[12738:12801](+)"
                     /alternative_weights="1973.2"
                     /alternative_weights="1991.2"
                     /alternative_weights="2009.2"
                     /alternative_weights="2027.3"
                     /alternative_weights="2045.3"
                     /alternative_weights="2063.3"
     gene            13102..14826
                     /locus_tag="APK71_RS25555"
     CDS             13102..14826
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327827.1"
                     /locus_tag="APK71_RS25555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_370592531.1"
                     /transl_table=11
                     /translation="MLLCSVAAAGAAVAQPLVLGHTLDLLLRDGDAGWWLALSAGLLLG
                     EVLLDSATSLCTGRCTATWTAAVRLRALRGLLRAVPDQARALPPGDVGTRLTLNAADAG
                     GAPAARAALAASLITPLGALGALAFVDLWVAACVLAGLPALALVLRSFARDTGATVAAY
                     QRTQSLIASRLLEALEGAATVGAAGTVDRERARVLAPLAELAERGRHMWALHGRALARS
                     GALVPLLTLAATAVGGLRLAAGELSVGGLLAAGRYAQLTAGVGAAASLLGAIVRARAAR
                     HRTRELEGMKPLTYGTRRLPPDGPGEVELRGVRVVRDGRQVLRADGVRVPGGSTVAVVG
                     RGGAGKSVLAAVAGRLVDPDEGHVLLDGVRLDRLTRDALRTEVAYAFERPVLGEGTVAE
                     AVAGGARQPSREQVREAARAAGADGFVRRLPHGYDTPLAQAPLSGGEHQRLGLARAFAH
                     AGRLLVMDDATSSLDTATEHEVNLALRRSVRPGTRLVVAHRPSVADRADLVLWLEEGEV
                     RAVGTHRDLWRAAGYRAVFGAGADADGTGAAADGPVPPGAGEAEPSVRRQEPEEAHP"
     gene            14823..16730
                     /locus_tag="APK71_RS25560"
     CDS             14823..16730
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019359197.1"
                     /locus_tag="APK71_RS25560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_079080670.1"
                     /transl_table=11
                     /translation="MTSAGHRAQAPDDAGTGDAGAGAVRRLAPSARRFLARRWGVLVRL
                     ALWSLAESGQAFLVGYGVARSVDDGFLAGDPRRGLLWLAVAVAAVLTGAPVVRGVFAQL
                     AGLTEPLRDALVRRAVDRSLVRVAAGGSGGPDRAAVSRLTNQVEIARDSFAGLVLTLRS
                     FVFTAAGALLGLLSLHPALLVVVMPPLAAGLALFLVTLRPMAAAQRRALAADEALGDHA
                     ARARAALRDLTACGTGPAAERRGADLVADAAAAARTLAGWAAVRTAALGVAGHLPVLAL
                     LVAVGWLRGRGVSAGALLGAFTYLVQSLLPALHTLMTALGAAGARLLVVLDRIVGPPPD
                     PTDAPVATASRADTADGHGHGHGRVHCHGRVHCHGTGGRSPDGASPAQHGAAPVPALEL
                     RSVTLSYGARAEPVLDSLDLSVAAGEHLAVVGPSGIGKSTLTRLAAGTLAPSGGEVRVA
                     GSPVAGRTAPELAALRVLVPQEAYVFSGTVADNLAYLRPDAGREELDAAVRAFGLRPLV
                     ERLGGLDAPVRPVELSPGERQLIALVRAHLSPAPLLLLDEATCHLDPASEARAEEVLAA
                     RPGTLLVVAHRLSSAVRADRTLVLDGVRAVCGTHDELLGRSPLYRDLTGHWCARPSRRP
                     "
     gene            complement(16765..17370)
                     /locus_tag="APK71_RS25565"
     CDS             complement(16765..17370)
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031103.1"
                     /locus_tag="APK71_RS25565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_158716757.1"
                     /transl_table=11
                     /translation="MGEMVRIVVVHDETLLRSALAHLLRSDDRLDVSSQCPDADGEARV
                     TPPTDVCVVDGECLTGPDDGRAVRLRARYGDRLVVLTTAKRPGVLRRAFDGGALGLVDK
                     NAPAHRLITAVHTVAKGERFLDETLTVALLEGAEMPLTTRELSVLALASQGAPIAEIAA
                     RLHLSRGTVRNYMATAIRKVGARNRVDAIRIVQSAGWT"
     gene            17907..18773
                     /locus_tag="APK71_RS25570"
     CDS             17907..18773
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389025.1"
                     /locus_tag="APK71_RS25570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4132 domain-containing protein"
                     /protein_id="WP_055469251.1"
                     /transl_table=11
                     /translation="MGWLAAGDRYEVALVEGRVVARATSATRDGHERTLPAEIRDRPEV
                     VELQRFAEWLDRHAAECAAQVTAWMVSSLPVPAGLLAQVWPDEAWRAALRDIVVVGEGP
                     DETGFLRDADETGGLRVVNLDGETARLTSPTVTMPHPVLLPDLEELRTFAAEAGVVQGV
                     EQIHRATWLKPAGTDGGADSVSEFAGAEYRSWFHLSARATSLGYRISGSAVVDRVRDDG
                     RTVTARVGMSDPYTEEKAWTGRLTWHHGDDRGRLPLREVGPVAWSEGMRMAAALHAGRT
                     VPTDDAR"
     misc_feature    22551..22560
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 18.16"
                     /tool="antismash"
ORIGIN
        1 agctgggtgt agagggtcag cgaggtgtgg ccgggggaga ggacgaagcg gtcacggccg
       61 gtccactcgg gatcggcggg gtcgtgacgc atcaccttct gaaagatcgt gtacgcggcc
      121 ggggcgagcg ccatggccgt ccccgggtga ccgttgccca ccttctgcac ggcgtcggcc
      181 gcgaggatcc gggcggtgtc gacggcacgc cggtccagtt cggtccattc gaagcggtcc
      241 gcgctgtcca ccgtctgctt gctcgcctgc gtgctcatct tcaagaaatc ctcgatcgga
      301 gcggagtagc tggtctgaag tgttcaaatc taaaagtctg actttttgga gtgaaggtcg
      361 tggtgtgcca gcctgtggtg aaactgggac acgccccggc cacggggcgc acgggcggga
      421 cggcgcgaga aggacatggc ggacgaacac caccaagacg gcgagggcgg ccggggtgcc
      481 gacggaggaa gcggcgaggg catcaggacg ttccccttcc cggtcgatct cagcctcctc
      541 ggtgtcggca tgcaggtcgg gcccatgggt gccggccgca cgtggcacgc gcacgccccg
      601 ctgcaccgcg tgcaccgcat cgacttccac accgtcatgc tcttcaccgg cggtccggtc
      661 cgtcacatga tcgacttcgc cgagtacgag gcgtcggccg gtgatctgct gtggatccgt
      721 cccggacagg tccaccgctt cgcgcccgag ggcgagtacc gcggaacggt gctcaccatg
      781 cagcccggat tcctgccccg cgccaccgtg gaggccaccg gcctctaccg ctacgacctg
      841 ccgcccctgc tccaccccga cgaggcccgc ctcgccggac tgacggcggc actcggccaa
      901 ctgcggcgcg agtacgagga cgcgaccacc ctgccgctga gcctgcacac cgccgtgctg
      961 cgccacacgc tctccgcgtt cctgctgcgc ctggcacacc tggcggccgg ctcggcgcgg
     1021 gaggggcgca cggacgcgcc gggggacagc accttcaccc tcttccggga cgccgtcgag
     1081 cggggcttcg ccaccaacca cagcgtcagc gcctacgccg acgcgctcgg ttactcccgc
     1141 cgcaccctcg tgcgcgccgt gcgggccgcc accggcgaga cgcccaaggg gttcatcgac
     1201 aagcgggtcg tcctggaggc caaacggctc ctcgcccaca ccgacctgcc gatcggccgg
     1261 gtcggcgccg cggtcggctt cccggacgcc gcgaacttct ccaagttctt ccagcagcac
     1321 accgaccaga caccggcggc cttccgcgcg gagctgcgct gaaggccgcc cccgcgcgac
     1381 gaacggcccc acggtgcgtg gagccgcagg cacgacgacg gcccccacgg tgcgtggagc
     1441 cgcacgcacg acgaaggggc tccatgccgg gtggagcccc ttcgccctcc tgcggggggt
     1501 tgttcgcggc tcagtggccg aagccgaacc agttcacgtt cacgaagtcg gcgccctggc
     1561 cgctggtgaa ggtcaggtag acgtcatggg tgccggtcac cgaggagatg ttcgccggga
     1621 tcgtccgcca cgactgccag ccgcccgtgt tgcccacggc gaagctgccg atcggcgtgc
     1681 tggtacggct gtccaggcgc acctcgacca ggccgctgac cccggcggcc gcaccgctgg
     1741 ccacccgggc cttgaactgg gtggcgggac tcgaaccgaa cttgacgccc ttgtactgcg
     1801 cccagtcgcc gttggcgagg gcgccgaggt tgcggccgcc gcccgagtcg gaggtggact
     1861 cggtcagggt gccggactgg gcgtcgtacg actcggcctc gatggtgccg tacgcgtcgc
     1921 ggtcaccgcc ggtcggcggc ggcgtggtac cgctcccacc ggccgacagc acctggacgt
     1981 agtccacgag catggagtgg ccgggctggg tgccgccgtc cgggccgccg ccgaaggcgt
     2041 ccgggaagcc gccgcccatc gccacgttga ggatgacgaa gtacccgtgg ttggtggcgt
     2101 tcgcccacgt cgtcgcgtcc acctggttgg cgcggacggt gtggaaggtg gtgccgtcga
     2161 cggagaagcg catctcctcg acgctcgtcg agcggtccca ctccacccgg taggtgtgga
     2221 agccggcctg gcaggtggtg ccggggcagg gggcgttgcc gccgatgccg ctggtctcgt
     2281 tgcacgggcc gccgggcgag gtgccgcagt gcagcgtgga ccagacggtg ttgaggccct
     2341 gggtgttctc catgatgtcg atctcgccga cgccgggcca gttccagtag ttgccccggt
     2401 agggcgcgcc gagcatccag aacgccggcc agtagccctt ggccgcggcc ccggtgacgt
     2461 tcgggacctg gatgcgggcc tccacgcgca gcttgccgcc ggccgggggt gcgaagtcgg
     2521 cgcgcttggt ctcgatgcgg cccgaggtcc agttgccggc gccgtcgcgc tgcggggtga
     2581 tgcgcaggtt gccgctgccg tccagcgaga cgttgctcgg ggaggaggtc atcgtctcga
     2641 tctcgccggt gccccagttg gcggggccgc cggggtacga ggtgccggtg tcgtactgcc
     2701 agttggccgt gttgacgccg gagccggccg cgccgtcgaa gtcgtcggcg aagacctgcg
     2761 tccagccgga cgggggcggg ggcgcggcgg cgcccgccga cggtcccgtc acggccgtcg
     2821 ccgccgcggc gaggccgagc gtgccgacga cggccaccag tgcccggcgc agcggccggc
     2881 gtctgggcgg gttgccggat gtctgactca tgtgggggtc gcctctcggt gcgggggtgg
     2941 gaagcggtgc gcccgagcgc gctccgggga ggaggagctg atgatgagag cgctctcaga
     3001 gtgccgccaa tgtgctcccg gtcctcgtcg ccgtcaagag gtgaagccga gaaagtcctt
     3061 gccgcgcagg ggagttcagc ccgtgaaggt cgcgaacgtc acgaaagtgc cgcacgggcg
     3121 gacgggcgca cgggcgggcg gacgggcgga cggcacgtcg gagccccggc gggccggggg
     3181 cgccgacgtg ccgccccggg cacgggcacc cggccgtgcc atgatcggcg ccaggcgcgc
     3241 caggcgcagg cacggcacgg gcacggctcg gtgacggaag gatgcggacg acgtgaggct
     3301 gacgatgctg ggcggcggcg ggttccgggt gccgctcgtg tacggggcac tgctcgggga
     3361 ccgcgccgag gggcgcgtga ccgaggtcgt cctgcacgac accgacgcgg cccggctggc
     3421 ggcggtgacc agggtgctgg cggagcaggc ggccgacgtg cccgacgcgc cggcggtgac
     3481 cgcgacgacc gacctcgacg aggcgctgcg cggcgccgac ttcgtgttct ccgcgatccg
     3541 cgtcggcggt ctgcagggcc gggccgacga cgaacgggtg gcgctcgccg agggcgtcct
     3601 cggccaggag acggtcggcg cgggcggcat cgcgtacggg ctgcggaccg tcccggtcgc
     3661 cgtcgacatc gcccgccggg tggcccggct ggcgccggac gcctgggtca tcaacttcac
     3721 caacccggcc gggctggtca ccgaggccat gtcccggcac ctgggcgacc gggtcgtcgg
     3781 catctgcgac tcgccggtcg gcctcggccg ccgcgtcgcc cgcgtgctgg gcgccgaccc
     3841 gggccgcgcc ttcgtcgact acgtcggcct caaccacctg ggctggctgc gcgggctgcg
     3901 cgtcgagggg cgcgacgaac tcccgcggct gctcgccgac ccggacctgc tcggttcctt
     3961 cgaggagggc cggctcttcg gcccggagtg gctgcgctcc ctcggcgcga tccccaacga
     4021 gtacctgcac tactactact tcaaccggga gaccgtccgc gcctaccagg aggccgaact
     4081 cacccgcggc gccttcctgc gcgaccagca ggcccgcttc tacgacgaga tgcgccgccc
     4141 cgacgccccg gcgctggcca cctgggaccg cacccgtgcc gaacgcgagg ccacctacat
     4201 ggccgagaac cgcgagacgg cgggcgcggg cgagcgcgag gccgaggacc tgtccggcgg
     4261 ctacgagcag gtggcgctgg cgctgatgcg cgccgtcgcc cgcgacgaac gcaccaccct
     4321 catcctcaac gtccgcaacc gcggcacgct ctccgtcctc gacggcgacg cggtgatcga
     4381 ggtcccctgc ctggtcgacg ccaacggcgc ccacccgatg gcggtcgacc cgctgccgga
     4441 ccacgccacc ggcctggtct gcgcggtcaa ggccgtcgag cgcgacgtcc tgaccgcggc
     4501 cgggaccggc tcccgcgcgg cggcggtgcg ggccttcgcc ctgcaccccc tcgtcgactc
     4561 ggtggacgtc gcccgccgcc tggtcgacgg ctacctggcg gtgcacccgg ggctggccta
     4621 cctcaggtga ggcccgccgg cgcggaggtc gccggggcct gggcggtggc cgccggccgt
     4681 gccggttccg gcgacggcac gggcgccggg aggtccggga ggcggtgggg cagggacggc
     4741 gggagcaggg ggcgcggtcc ggacaccacc gcgtagtcct ggcccaggaa cggcggctcc
     4801 agctcacccg ggtcgtcccc gagggccagc cgcaccgccg cccacggcac gttgaggccg
     4861 cacagcgcca actggtgcag cccgccggcc gggcgggtgt tgacgtccat caggaccggc
     4921 cggtcgccgt acatccggaa ctgcacgttg gacaggtggt gcagcccgaa cgcctccgcg
     4981 atgagccgtg ccggggccag ccaccgttcg tgcagggtga acccccggcg gcggccgttc
     5041 ttcgtgcggc ccacggccag ccggacccgg ttgtcgggcc ccgtgaggca gtccaccgag
     5101 acctccggct gctccaggcg cggcatcacc agccagtcca cgggctcctc ggccgcccgc
     5161 agcgcctgga ggaccagggg cagcggcacc gacgggctcg ggaagccgtt gaggtgcgcg
     5221 agcgagaagg ggtcccgcgt gaccatccgg aagcccacgc cgcccgcgcc ggacgccggt
     5281 ttgaagcatg cccggtggcc gccgtcctcc aactcctcca cggcgaggac gagttcctcc
     5341 gcggtgcgca cccgccacca cggcggcacc ggcacgccga tcgcccgcac cgcctcgtag
     5401 gccgtcacct tgtcgccgaa cagggccacc gcctccggcg agggggccag cagagccgta
     5461 ccggccgcct cgaactcggc acggtgcgcc acgatcgccg cctggtgcag ccggggcacg
     5521 aacacgtcga tgccgcgccg tgcgcactgc gccagggcga actcgacgta accggccggg
     5581 gagagcccct cgggttccag gtcggcggtg tccgcggcgg ccagtacggg ggagtccggg
     5641 tcgccgtgcg tggcgtggat ctcgacggcc cggtcggcgg gatttctccg caactggtcc
     5701 atgaagaaga cgttctccgc gtacgtgcgg ttgagccaga cgcgtacggg agaagccatg
     5761 caagccgcct tccaagggtt cgcgggcagg gcggagcggg ccgtgcccgg ccaggggttc
     5821 gaaagggaca ccgagccgct ctgcgcgagg aatggggcgt ggcggtggtg ttggggcgat
     5881 cataggggta cgcgcggccc ggagcgcaac gcgcttcaca cggatgcctc ggcccggccg
     5941 cacaccggct cgcggggccc gacggggcgg acgccgccgg tgcaccttgt gaccggggcg
     6001 gcgatgtgat ctcgtggcgc aggacgcgcc ggaggcgccg gacgcgtcgg cgggggaggg
     6061 tgggggatga cgtcgagggc cgcggcagcg ggcagggtct gggccgtcag cgacctgcac
     6121 atcgggtatc cggagaaccg ggccctggtc gagcggatgc gtcccgagtc gggggacgac
     6181 tggctcctgg tggccggcga cgtggcggag accgtcgccg acgtccgctg ggcactcgaa
     6241 accctcgcgg accgcttcgg ccgggtcgtg tgggtccccg gcaaccacga actgtggacg
     6301 catccccggg acccggtcgc cctgcgcggc gtcgcccgct acgaacacct cgtcgcgatg
     6361 tgccgcgaac tgggcgtgac cacacccgag gacccctacc ccctctggga gggcgagggc
     6421 ggcccggcgg tcgtcgcacc gctcttcctg ctctacgact actcgttcct gcccccggga
     6481 tgcgcgacca aggccgaggg cctggagtac gcccacggca ccggcatcgt gtgcagcgac
     6541 gagtacctgc tgcaccccga tccctacccc agccgcgagg cgtggtgccg ggcgcgggtg
     6601 gccgagaccg agcgcaggct cgccgcgatc ccggcggacc tgccggtgat ccccgtcaac
     6661 cactacccgc tgcaccgcca tccgaccgac atcctgtggt accccgagtt cgcccagtgg
     6721 tgcggcacct cgctgaccgc ggactggcac cgcaggttcc gggtcgagac catggtctac
     6781 ggccacctgc acatcccgcg caccacctgg cacgagggag tccgcttcga ggaggtctcg
     6841 gtgggctacc cgcgcgagtg gcgcaagcgg cccgggccgc ccggacggct gcgccgcatc
     6901 ctgccctccc gagcggcgtc cgaggcgccg acgagccccg aggtgacccg ttgatcgagg
     6961 aactgctgcc cgaccccgtc gtcgccgtgg aggcgttcgg cggcgacgac gccggacacc
     7021 tgcccctctt cccggaggag gaggagttcg tcgcgcgggc ggtcgccaag cggcgccggg
     7081 agttcaccgt cgtacggtcc tgcgcccgcc gggccatgga gaagctcggc gtgcccccgc
     7141 aggccgtgcc gaccggcgaa cgcggggccc cgcgctggcc ggccgggctc accggcagca
     7201 tgacccactg cgacggctac ggcgccgccg ccctggtccg cctgaccgac ctggcctccc
     7261 tcggcatcga cgcggaaccc gacgggccgc tcccggacgg cgtcctggag gccatcgccc
     7321 tgcccgccga ggcggcccgc ctgcgccggc tcggcgaggc ccggcccggt gtccactggg
     7381 accggctgct gttcagcgcc aaggagtcgg tctacaaggc gtggttcccc ctcaccgggc
     7441 agtggctgga cttctcggag gcggacatcg agatccgcgc cgacccggcc gacccgtgcc
     7501 gcggcaccct gcacgccgcc ctcctggtgc cgggaccgac cgtgggcggc aggcgcctgg
     7561 cccgcttcga gggccgctgg gccgcccgca acggcctggt cgccacggcg gtcgcggtcc
     7621 cgtacccctg accggccctc cggccgcccg cgcccgtcac gtgcgcgggc accactcccg
     7681 cagcagtcgg aagaacgcct cctcgttccc cgcgaggccc gccgccgcga gggcctgctc
     7741 cgcctccgcc agcacggagg gcgggacgag cggcggcccg ggcggggcgc ccggacccgg
     7801 accggtgtcc aggccggccc gcacggtgtg caggagacgc aagtaggcct ggacggcgcc
     7861 gcgttcgcgg tcggtcagta cggcggtggt catcggtcgg ctctccccac aatgacgtca
     7921 gcggtcacgc gcccccgcac ggcgacggca ccctcccagc ttgccgctca ccactgacaa
     7981 tcccgcccgg ccgcgcctga acggcggccc cgtccgcacc gatcgggcca tcgctcggtc
     8041 aggtgcgcga cagacgcacg accgagccgc ggccggggcg gccggctcac ggctcggggc
     8101 gctgcacact ctccagcagc atgtccagcc actcggcgac cttgtcgcgg tgctggtcgg
     8161 tgggcagttg cgcggcccgc cacgcgatgc cgcgcacccc gtggtcctgg agcagccgct
     8221 ccagggggtc ctcgtcggcg gccgcctccc gctcccggtc ggcgagttgc tggagcagtt
     8281 cctgctcggt gcgctgcagg gcgcccgcga gtgcctcggg gtcctcggcg gtgaggaagc
     8341 cggcgtgcac ccggaagaag cgctggatgg cgtcgcagtg ctccatggtg gggcggcggt
     8401 cgccgttgat gagcgcgccc gcctgctgcc gcgacatccc cgcgccgtcg gcgatctcct
     8461 gctgggtgta cttgcggccg ttcggcttca gccgggtgcg gcgcagcagg tcaagacgct
     8521 gaacgaaccg ggtctgcaca tcgggctcgc ccgcgggccg gccgccgagc agggccccca
     8581 cgacgggctc ggggacgccg gaggcgacgg agagccggct gacgtcgaag acctcggtgt
     8641 gcggcacccc gaggcggtcc gcgagggccc ccacccgggc gacgacggcg gtcagcgtgg
     8701 tggccggcat ggcgcccgga ccctcgaagc cacccgtcac cgacagctcc cctacgtctc
     8761 tcacaggcct cacaggcttc tcacaagcag ttgccgtgaa cttcccggag agtagcctgc
     8821 cgctcgaact cacatccaga catcgccaca actgtggcct atttgagccg tcaacaggca
     8881 cgaaatgcca cgatagttga cacgcctcgc gtcggggcgc caggatgcgg gacgccgcga
     8941 gaaggccgca taggcaagag gggtgacctc ccgatggcat ttcaggcagg agggcagcgg
     9001 ccggcgccgc ggcccggacc cgcgaccccc gaggcccagg cctatctcca ggactacacc
     9061 gcgctgctgg agtccgtccc ccatccctcc ctcgtcgtcg accaccgctg ggacgtggtc
     9121 ctggccaacg gtgccttccg gacactcttc cagggggcgg gcccgcatcc gacggccatg
     9181 ccggacgaca acttcctcag gttcgtcctc ttccacccgg acgccgccac cgtcctcggc
     9241 gagcacgagt cgagctggtg cctgcccatg ctggcgcact tcgccgccac cctggagcgg
     9301 tacggccacg accccggcct gcaggccgtc cgccgggaca tcgcccagga ccccttcatg
     9361 gaggccgcct accgccaggg cctgccgcac tggatccgca ccgtcggcgc ccgcgccgtc
     9421 gaacacgacg gtgccgtacg gccgttgcac caccccgacc cccgccgggg caccaccgaa
     9481 tgccgcgtgg tggtcgagac gcccggggcg ctccggcaac tcggctacac ccggctcacg
     9541 ctcgtcctgc gggaaccgcg ccgcgcagcg caccggtcgt cggccgtccg gcgtgccgcc
     9601 tcccacctga gggtcgtccc cgccgcggag tgaccgcggg tcacgggcgg ggcggagccc
     9661 cgctcccgga cggctcctcg acgggcccgt ccgacggcgt gcccgccgcg ccacccgggt
     9721 gcgcacccgg tcccgcccgc ccggcgggtc ggccacgaac cgctcccgta cgacgccggc
     9781 gcacgcgttc tccccgttca ccgggcgtac ggcctcgtcg gtgccgtggg tgacgaacag
     9841 gacggcgtcc gccgcaatcc gcccgctccg ctctcctccc ccccccccgc gaagttacct
     9901 gtgcgttccg cacgtcggag tggtgacagc ggcaactgtg cgcggcggca cggtgcgtga
     9961 cagcgtcgtc cccgtcagcg accggtggga gggagaaggc gtgaacaagg gctacgccgt
    10021 gtactgcgac gcggacccgt acttctacga cgccccgcac cgggcggcgg accggaccgg
    10081 cacctcgcgc ccccggtacg ccgcggcctc ctcgcccgtg ccgcggggat ggcggcgcaa
    10141 cgagagcggg gactggctcg cgctgcgccc ggccggcgcc cgcctgcccg accaggggtg
    10201 gaagatccac gtctccgcct gcctcgacaa cgccgagtcg gtgctcgacc gcgtgtggcg
    10261 gcactgcgtc gccggcggga cggccttcaa gttcgtaccc ggccgccacc tgctgcacca
    10321 gcgcaacgcc aagtacgccg accgagcggg cagcggcaag ttcgtcaccg tgtacccggc
    10381 cgacgaggcg gacttcgaac gcctcgtcgg ggagctgtcc gacctgctgg ccggcgagcc
    10441 cggaccgcac atcctcagcg acctgcgcat cggcgacggc cccgtgcacg tccgctacgg
    10501 cggcttcacc cgccgcgact gctacgacgc ggacggcgaa ctgcggccgg ccgtggcccg
    10561 cccggacggc gtgctggtgc ccgacccgcg cgggccggtc ttccgcgtcc cggactgggt
    10621 cgtcccgccc gccttcctgg gcccccacct cgacgcccgc tccgcggtga ccgtgaccgg
    10681 catgccctac gccgtcgagt cggcgctgca cttctccaac ggcggcggcg tctacctcgc
    10741 ccgcgacacc cgcaccggcg agcgtgtcgt cctcaaggag gcgcgtccgc acgccggtct
    10801 ggcggccgac ggcgccgacg ccgtgacccg gctgcaccgt gaacgacggg cgctggagcg
    10861 gctgtcgggc ctggactgca cgcccgaggt gctcgaccac ctcacggtcg gcgaccacca
    10921 cttcctcgtc ctggagcaca tcgacggcaa gccgctcaac acgttcttcg cccgccgcca
    10981 cccgctcatc gaggccgacc cgggggagcg gagactcgcc gagtacaccg cctgggccct
    11041 cgacgtgcac gcgcgggtgg aacgcgccgt cgaggcggtc cacgcccggg gcgtcgtctt
    11101 caacgacctg cacctgttca acatcatggt ccggggggac gacaccgtcg ccctgctgga
    11161 cttcgaggcc gcccaccccg tcgacgaagc gggacggcag accgtggcca acccgggatt
    11221 cgtggcgccg tccgaccggc gcggcgtcgc ggtggaccgc tacgcgctgg cgtgtctgcg
    11281 gctcgcgctc ttcctgccgc tcaccagcct gctggcggtc gaccggaaca aggcggcgca
    11341 tctcgcggac gtggtggcag agcagttccc ggtggaccgg gcgttcctgg acgaggccgt
    11401 ggacgagatc acgcgcgccg gcggcgcccc gacggcggga ccgggcgccc gtgcgacgct
    11461 gtcgcggccg aacggggcgg ggacgcccgg ggccgccggg acgggggagc cgcggagcgc
    11521 gggtcccgtg gtacggcggg ctcacgggcc ggtggtgccg gtccggccgg acgactggcc
    11581 gcgcagccgg gactccatgg ccgaggcgat ccgtgcctcc gccacaccct cccgcaccga
    11641 ccgcctcttc ccgggcgaca tagcgcagtt cgccacggcc ggcggcgggc tgtccttcgc
    11701 ccacggcgcg gcgggcgtgc tgtatgccct ggccgagagc ggagccggac gggacgaggg
    11761 cggcgagcag tggctgctgg agcggaccgg gcgaccgccc tcgggcacac cgctcggctt
    11821 ccacgacggg ctcgccggga tcgcctggac cctggagcgc ctcggccacc gcgaccgggc
    11881 cctcggcctc accgaactcc tcctcgacca gcccctcgac cacctgggcc ccgacctgca
    11941 cagcggcacc gccggcctcg gcctcgccct ggactcgctg gccggctcca ccggagagac
    12001 cgcaccgcac gcggcggccc tgcgctgcgc cgaacgggcc gccgacggtg cgccggccga
    12061 ccgcgccggc cgtggacggg cccgcgccgg gctgctgtac gggggcgcgg gccgggcgct
    12121 gctcttcctg cggctgttcg cccgcacccg ggacaccgcc ctcctcgacc tcgcccggga
    12181 cgcgctgcgc caggacctgg cccgctgcgt gcgcggcgcg ggcggcgcgc tgcaggtcga
    12241 cgagggctgg cgcacgatgc cctacctcgg cgccggcagc gtgggcatcg gcatggtcct
    12301 cgacgactac ctggcgcacc gggccgacga ggagttcgcg cgggccagga acgagatcgt
    12361 ggccgccgcc caggcgatgt tctacgccca gccgggcctg taccggggcg tggccggcat
    12421 ggtgctgtac ctcggccgca ccacggccgc ggtgcccggc acgggccccg ccgccgtacg
    12481 gcgccagctc gacgcgctgt cctggcacgc cctgtcctac cgcggacgcc tggccttccc
    12541 cggtgagcag atgatgcgcc tgtccatgga cctctccacc ggaacggccg gatgcctgct
    12601 ggccgtcgcc tccgtcctcg gcgacgcgcc cgtcgggctg ccgttcctgc caccgctgcg
    12661 ccgaagcggc gcccccggac ccggccccac tcggggtcgt gagaaagcac acccgttgcc
    12721 gaacgaaagg aagtcgtcat gaacctgttc gacctgcagt cgatggagac ccccaaggaa
    12781 gaggccatgg gggacgtcga gaccggcagc cgcgcgagcc tcctgctctg cggcgacagc
    12841 agcctgagca tcaccacctg taactgacgc cggaggtgac ggccgcggcg acgtggtgag
    12901 ccgtgtcgcc gggcgcgggc gccccgggtt ccggcccggg gcgccgacgc ctgcccggaa
    12961 cgtacggagg tttcgcaggt gcgaacgaga agagccgctg tgtcgcaggc gccagggagg
    13021 cggcgagggg ccgacggacc ggcgtccggg aagcggcacg gggccgacgg cccggcgccc
    13081 gggcgcgcgc cggaggcact ggtgctgctg tgctcggtcg cggcggccgg tgcggccgtg
    13141 gcccagcccc tggtcctcgg ccacaccctc gacctgctcc tgcgggacgg cgacgcgggg
    13201 tggtggcttg cgctgagcgc cgggctgctc ctgggggagg tactgctgga cagcgcgacc
    13261 tccctgtgca ccggacgctg caccgccacc tggacggcgg ccgtccgcct gcgcgccctg
    13321 cgcggactgc tgcgcgccgt gcccgaccag gcgcgggccc tccccccggg ggacgtcggc
    13381 acccgcctca ccctcaacgc cgccgacgcg gggggcgccc cggcggcgcg ggcggcactg
    13441 gcggcctcac tgatcactcc gctgggcgcc ctcggggcac tggccttcgt cgacctgtgg
    13501 gtggcggcct gcgtgctggc gggcctgccc gccctcgccc tggtgctgcg ctccttcgca
    13561 cgcgacacgg gcgccacggt cgccgcctac cagcgcacgc agtccctgat cgcctcgcgg
    13621 ctcctcgaag cgctggaggg cgcggccacc gtcggcgccg ccggcaccgt cgaccgggag
    13681 cgcgcccgcg tcctcgcccc gctggcggaa ctggccgagc ggggccgtca catgtgggcg
    13741 ctgcacggac gggcgctggc caggagcggt gccctggtcc ccctgctgac gctggccgcc
    13801 accgccgtcg gcggactgcg cctggcggcg ggcgaactga gcgtgggggg cctgctcgcc
    13861 gccggccgct acgcacagct caccgcgggt gtcggcgccg ccgcgtcgct gctcggcgcg
    13921 atcgtacggg cccgcgcggc gcggcaccgg acccgggagc tggaagggat gaaaccgctg
    13981 acgtacggaa cgcgacggct gcccccggac ggaccgggcg aggtcgaact gcgcggcgtg
    14041 cgcgtggtgc gcgacggcag gcaggtgctg cgcgccgacg gggtgcgggt gccgggcggc
    14101 agcacggtcg ccgtggtcgg acgcggcgga gcgggcaagt ccgtgctggc ggccgtggcg
    14161 ggccggctcg tcgatccgga cgagggacac gtgctgctgg acggcgtccg gctcgaccgc
    14221 ttgacgcgcg acgcgttgcg caccgaggtg gcctacgcct tcgaacggcc cgtgctgggg
    14281 gaggggacgg tcgcggaagc ggtcgcgggc ggggcgcggc agccgtcccg cgagcaggtg
    14341 agggaagccg cccgcgcggc gggcgccgac ggcttcgtac gccgtctgcc gcacggctac
    14401 gacacaccgc tggcgcaggc gcccctctcg ggcggggaac accaacggct cggcctggca
    14461 cgggcgttcg cgcacgccgg acggctgctg gtcatggacg acgccacttc gagtctggac
    14521 accgccacgg agcacgaggt gaacctggcg ctgcgccgct cggtccggcc cgggacccgg
    14581 ctcgtggtcg cccaccggcc ctcggtggcg gaccgggcgg acctggtgct ctggctggag
    14641 gagggggagg tgcgcgcggt cggaacgcac cgcgacctgt ggcgcgcggc cggctaccgg
    14701 gcggtcttcg gcgccggcgc ggacgcagac ggcaccgggg cggcggccga cgggcccgta
    14761 ccgccggggg cgggggaggc cgaaccttcc gtacgccgtc aagaacccga agaggcgcac
    14821 ccgtgacgtc cgccggacac cgcgcgcagg cacccgacga cgcgggcacc ggggacgccg
    14881 gggccggggc ggtgcgccgg ctggctccgt ccgcgcggcg cttcctcgcc cgccgctggg
    14941 gcgtgctggt gcggctggcg ctctggtcgc tggccgagtc ggggcaggcc ttcctggtgg
    15001 gctacggcgt cgcccgctcc gtcgacgacg gcttcctcgc cggggatccg cgccgggggc
    15061 tgctgtggct cgcggtcgcc gtggccgccg tactgaccgg cgccccggtc gtccgggggg
    15121 tgttcgcgca gctcgccgga ctgacggagc cgctgcgcga cgccctggtg cggcgcgccg
    15181 tcgaccggtc cctggtccgg gtggccgcgg gcggctccgg cgggccggac cgggcggccg
    15241 tgtcccggct gaccaaccag gtcgagatcg cccgcgacag tttcgccggc ctcgtcctca
    15301 ccctgcgctc cttcgtcttc accgccgccg gcgcactgct cggcctcctg tccctgcacc
    15361 cggccctcct cgtcgtcgtg atgcccccgc tggcggccgg tctcgcgctg ttcctggtca
    15421 cgctgcggcc catggcggcc gcccagcgca gagccctggc ggccgacgag gccctgggcg
    15481 accacgcggc acgcgcccgt gccgcgctgc gggacctcac cgcctgcggc accgggcccg
    15541 cggccgaacg gcgcggcgcg gacctggtgg ccgacgccgc cgcggcggcg cggacgctgg
    15601 ccgggtgggc ggcggtgcgc acggcggcac tcggcgtcgc gggccatctg cccgtgctcg
    15661 ccctgctggt ggcggtgggg tggctgcgcg ggcggggggt gagcgcgggc gcgctgctgg
    15721 gcgccttcac ctacctcgtg cagtccctgc tgcccgccct gcacacactg atgaccgcgc
    15781 tcggcgccgc cggggcccgg ctgctggtcg tcctcgaccg gatcgtgggc ccgccaccgg
    15841 accccaccga cgccccggtg gcgacggctt cccgagcgga caccgccgac ggccacggcc
    15901 acggccacgg ccgcgtccac tgccacggcc gcgtccactg ccacggcacc ggcgggcggt
    15961 cacccgacgg tgcaagcccg gcgcagcacg gggccgcccc ggtcccggcg ctggaactgc
    16021 gctccgtcac cctgtcctac ggcgcccgtg ccgagcccgt gctggactcg ctcgacctga
    16081 gcgtcgccgc gggggaacac ctcgccgtcg tcggaccgag cggcatcggc aagtccaccc
    16141 tcacccgcct cgccgcgggc acgctcgcgc cgagcggcgg agaggtgcgg gtggccggga
    16201 gcccggtcgc ggggcgcacc gccccggagc tggccgccct gcgggtgctg gtcccgcagg
    16261 aggcgtacgt cttctccggc acggtcgccg acaaccttgc gtacctccgg ccggacgcgg
    16321 gccgtgagga actcgacgcg gcggtacggg cgttcggcct gcggcccctg gtcgagcggc
    16381 tgggcgggct ggacgcaccg gtgcggcccg tcgaactctc accgggggag aggcagttga
    16441 tcgcgctggt ccgcgcccac ctgtcgcccg cccccctgct gctgctcgac gaggccacct
    16501 gccacctcga cccggcgtcc gaggcccgcg ccgaggaggt cctcgcggcg cggccgggaa
    16561 cgctgctcgt ggtggcgcac cggctctcct ccgcggtccg ggccgaccgg accctggtgc
    16621 tggacggcgt acgggcggtg tgcggcacgc acgacgaact gctgggccgt tcgccgctct
    16681 accgggacct gacgggccac tggtgcgccc ggccgtcccg gcggccctga gcgcggaccg
    16741 cccccgtgcg gcgccgcccg ccgttcacgt ccagccggcg ctctggacga tgcggatcgc
    16801 gtcgacccgg ttgcgggcgc ccaccttccg gatggccgtg gccatgtagt tgcggaccgt
    16861 cccccgggac aggtgcaggc gcgccgctat ctcggcgatc ggcgccccct gcgaggccag
    16921 ggccaggacg ctcagctccc tcgtggtcag cggcatctcc gcgccctcca gcagcgccac
    16981 ggtgagcgtc tcgtccagga agcgttcgcc cttggcgacg gtgtgcaccg cggtgatcag
    17041 ccggtgggcc ggggcgttct tgtcgaccag cccgagggcg cccccgtcga acgcccggcg
    17101 cagcaccccc ggccgcttgg cggtcgtcag cacgacgagc cggtccccgt accgggcccg
    17161 caggcgcacc gcgcgtccgt cgtccgggcc cgtcaggcac tccccgtcga cgacgcagac
    17221 gtccgtcggc ggcgtcacac gcgcctcgcc gtcggcgtcg ggacactgcg aggacacgtc
    17281 cagccggtcg tcggatctga gcaggtgcgc cagcgccgac cgcagcagcg tctcgtcgtg
    17341 caccacgaca atacgaacca tctcccccac ctcattgtcc ggcggcggtc ccgtacggac
    17401 cgccggctcc gcgcgccccc gcgcgccacg ggccatgtgc ccccaaccgg gacggcggaa
    17461 caccacgcgt acgcacgtgc gaacggcttc ggaggcaatg cgccgtcgcc gaagccgtgc
    17521 ggagggacgg gcgggacggg tggcccggtg aagaagggcg gataacacac cggtccgcgg
    17581 acggcgcggg ggcccggggg atccggcggg cggcggccgg ccccgccacc cgcgccctgt
    17641 cgtccaggcc acgagggggt tccggccacc ggagccgccc gcacccgccc tccgggtccg
    17701 ggcggacgcg cttttcggcc gctgccggat cggccgaaaa ccgccgctgc ccaatctggc
    17761 gcgaaaggca ccgcgccgca cgaggtcggg gactgtcggt gggcgcccct agtctttggc
    17821 caacacctca gcagagcgtg ctggttcaca gcccggctcg cgtgctgtgc cgtgtgttcc
    17881 ccgtggtggc gagaggcgaa gagctgatgg gttggctggc agcgggcgac aggtacgaag
    17941 tcgccctggt ggagggccgg gtggtggcgc gggccacgtc cgcgacgcgg gacgggcacg
    18001 agcgcaccct gcccgcggag atacgggacc ggcccgaggt ggtcgaactc cagcgcttcg
    18061 ccgagtggct ggaccggcac gccgccgagt gcgcggccca ggtcaccgcc tggatggtgt
    18121 cctcgctgcc ggtgccggcc gggctgctgg cgcaggtgtg gcccgacgag gcctggcggg
    18181 cggcgctgcg ggacatcgtc gtcgtcggcg agggacccga cgagaccggt ttcctgcgcg
    18241 acgccgacga gacgggcgga ctgcgggtgg tgaacctgga cggcgagacc gcccggctga
    18301 cctcccccac ggtcaccatg ccccacccgg tcctcctgcc cgacctggag gaactgcgga
    18361 ccttcgccgc cgaggcgggc gtggtccagg gcgtggagca gatccaccgc gccacctggc
    18421 tcaagcccgc cggcacggac ggcggtgccg actcggtctc cgagttcgcg ggcgccgagt
    18481 accgctcgtg gttccacctc tccgcccgcg ccacctccct cggctaccgg atctccggca
    18541 gcgccgtggt cgaccgcgtc cgggacgacg gccgcaccgt caccgcacgt gtcggcatga
    18601 gcgaccccta caccgaggag aaggcgtgga ccggccgcct gacctggcac cacggggacg
    18661 atcgcggcag gctcccgctg cgcgaggtcg gccccgtcgc ctggtccgag ggcatgcgca
    18721 tggccgccgc cctgcacgcc ggccgcaccg tgcccacgga cgacgcccgg tgaacgcacc
    18781 ccacgcacgc acacccgaga aaggcaagcg atcatgagcg acggcacgac cccggacggg
    18841 gcggtcgcag aggtggagga actgctgcgc gcgggagccg tactgccgcc gggcaccccc
    18901 cgggcaggcg accgcgccgt gcccgtgttc acccgcgcct accggcaccc gggcctggac
    18961 gaccggatcg tcgtacgcct gacgcccgag gacccgtccg ccgaggagcc cgccgggggc
    19021 ggcggcggat tcctcggcct gcggccggcg ggcgaaccgg tcgaggtcgg ggtcggacag
    19081 caccgggcga tgggcttccc cgaatgggtg ctggtccgcc accccgccga cggccatctc
    19141 gcgatgtccc tggtcgagga gatggacaag atcgcccgga cggtgcgctc ccgtccgaag
    19201 agggcccgcg ccgcctacga gtcggccggt gagcgcctcg cgggctcggt gccgcacttc
    19261 ctgcccacct tctacgagga ggccggccgg gtgttcctgg ccgcgggcca gcaggcgtac
    19321 gcctcccaga tgttcgtcaa cgcgcgcaag gccgagacgg cccacgccct gccgttcgac
    19381 gaggcccgca tggacgccgt gttcctggag ttcgccctcg ccgacgccgt gccgaccaag
    19441 gtgctctccg cctacgccaa ggggctggcg tcccgggtgc cggccgccac cgccttccgg
    19501 cacctgcgcg ggctgttcgt ccggctcgcc gcgcacggcg tggcaccgtc gagccccggc
    19561 gcgagcgacc tgcgcaggct ggcgaaggcc gccgcgggca agaacgcgct cgccgaggag
    19621 atggcctacc tgcgcgaggt gctgccgctg ccgggcaccc tcaaggcacc gcccggctgg
    19681 tggaaggccc acctggccgc cctgcgggaa ctgacccggc gcgaacccgg cgtccgcggc
    19741 accctgctgg ggctgctgcc cgagggctgg gagcaggacg acctgggcca gtggctcggc
    19801 ctgctggaga agaccggcgc gaccgaggga ctgtgcgacg ccgcgctgcc cgccgagacg
    19861 cggtccccgg acggcacggc cggctggatg cgcaggttcc tccacctgtg ccgcaccgac
    19921 gactggcgcc tcgcaccgcc cgagctgtac ccgctcgtcg accggctcgc cgacaccctg
    19981 cgcgccgaac tgcacgccga gggcggcacc ctgccgcccc ccgtcagcga cgtcgacctc
    20041 ctcgaccagc tcctcgccct gcgcatcccg gtcggcgacc ccgaggagcg ccccggcctg
    20101 ggcctgcagg aatgggcggc ccgagacgag cggcgcgacc tgctggccct cgccgccgac
    20161 agccgcttcc gcgcggcctt ccggcgcggc tgccccagct acgaacgcaa gggcatcgac
    20221 aggcgcaccg tgacccggct ggccgagtcg ccgggcggac gcccgatgct cgccgaatgg
    20281 gtcgccggtg tcggccgcag gtatctcacc agcaacctcg gcgagttcgc cgcctacgac
    20341 ggcccgttcc aaacgttggc gtggctgccg ggcgaggtcc tcgccaccgc cgagcaggag
    20401 gtgcgggacg ccctgggcac cggcatggcg ccgggcctcg cccgcgccct gcggtccggg
    20461 atcctcgacg aactgggctg gcccgcctgg gaggaggcgg tcggcacacc cgcgacgccc
    20521 gaggacgcgc ggagcaccct cgtgagcgag gcatggccgc acctgatcgt cttccgcgac
    20581 ggctgcgccc gggtgatcgg agccgagggc acggtcctca gccacgagat gcgcctcccg
    20641 gcgccctcgg agcgctcggg caccgaggcc cgctacgtgg acggcgggct cctcgtcttc
    20701 tggcagggcc tctcctcctc cggcttctcc ggctcctacg gctactggta cgcccccgac
    20761 accggcgcct ccccgcccac ggaggtcgac ggcgacgtcc gctccccgta tgcctgccac
    20821 gcgaacgaga agggcggaac caacggcatg cgcggcacct ccctcccgct ccccgggggc
    20881 ggccgggcca ccggaggccg cgtgctgcgg cggggagaca cccacgtgcc gcacggacgg
    20941 cccgtgatcg gcgacggcac gtcgtactgg gtctgggtca gggactggtc cgacgaggca
    21001 aacagtgcct ggttcgccta cgacccggcc gccggcacgg tgggggagcg cgacgagccg
    21061 gactggttca ggcaggggct gcgcgccgcg ccggagggca gcaccctcgg caccgcctgg
    21121 ctgctgcccg ccccctccgt cgccccggga ccggtgtccg ccccggtgga cggtgtcctc
    21181 ggctggcggg ttctcacgct gcccgacggc acacgacggg gcgaggacct ggccggccgc
    21241 tccgtcgtcg tccccccgcg cgtgggcgga aacccggagc acgcgctggt cttccccggc
    21301 accgaccggg tcgtgaccgt catgcgatgg tcgaccgacc tccaactgcg ggacgccgaa
    21361 ggcgcggtgc tcgcccacgt cgacggccac cagacggccg ggcccttctc cgccggcacc
    21421 ccgctgctgc cgcccctgcg ctactggccc ctgctccgcc cccgcgaccc gcagggctcc
    21481 gccgcactgc gccgggtcgg cgacgacacc gcggcggccc tgctggccgc ggccctggcg
    21541 gaggcacccg caggcaccgc ggaggaccgg gacccggtgc tcgcccccgt gcgcaccctg
    21601 ctgccggagg tcggccacga ggccctgcgc cggggcatca ccggtctggt ccggtacgcc
    21661 gccgagcaac agcgcaccct ggacgccgcc ctggcccggc tggacgcggc ggtccggggc
    21721 accgccccgg aggaaccccg ggccgcgctc ggcgacgccc tgctcgcctc cgcgctgaac
    21781 agcgtcggcc tcaccgaacg cgacgcgcgc tggtactacg acttccagca ctacctcttc
    21841 ggcctgccgc acctcctggc ccagtcgatg aaggacctgc ccgagcccgc caccgccggc
    21901 accccgcggc aggcgcccac cgggcacggg ccgctgaagc acctgaacgc ggtggccctg
    21961 cccgagctgc ccgccgtact ggcgctcagg gcggcctgcg aggccaccgt ggaggagcac
    22021 cggcaggccc tggacgtctt cctcggcgaa ctggacgccc agggactgac cgagctggac
    22081 cccggccact ggcgccgcgt ccacctggcc ctcgaacccc acgccttcga cagccccggc
    22141 gccacgcaca cgcaggggac cgtgctcggt ctgggcggcg gcgagttcct cgtcttcccc
    22201 gactcctggt accggttcgt ccgcgagtac ggcgactacg agatcagggg caggcactac
    22261 ggcgcggtcc accacgaccc ctccggccgc ttcgagacac ccgcaccctt caccctggtg
    22321 tccgaaaagc ccttcgtccc ggaaccggcc cggccgcccg gctgggtcgc cgccttccgc
    22381 gccgaactgg ccgagcgcgg ccccgcgccc tggcgccccg aggccgccga ggagttcgcc
    22441 cggctcaccg gggtcacccc gaccacggcc aggatggtcc tcgccgggat gccgcagatc
    22501 gacgacaagc gcacgaacgt gccctccgcg acgctcaaga ccatcggagt gaaggcggcc
    22561 gacgcccgcg tgtccaagga cgacctcaga tccctcgaca gcgccgccct gcgggccgtc
    22621 gtggccgccc tgctgcccgc cgaaccgtcc cggctgtgga cccacggccc cgacaccgcc
    22681 cgcgcggccg aggtctggaa cgaacgtctc ggccggcgca ccccactgcc cgaggacgtg
    22741 ct
//
