LOCUS       NZ_BBOK01000004        41185 bp    DNA     linear   CON 17-AUG-2024
DEFINITION  Streptomyces sp. NBRC 110030, whole genome shotgun sequence.
ACCESSION   NZ_BBOK01000004
VERSION     NZ_BBOK01000004.1
KEYWORDS    WGS; HIGH_QUALITY_DRAFT; RefSeq.
SOURCE      Streptomyces sp. NBRC 110030
  ORGANISM  Streptomyces sp. NBRC 110030
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1
  AUTHORS   Katano-Makiyama,Y., Hosoyama,A., Hashimoto,M., Tsuchikane,K.,
            Uohara,A., Kitahashi,Y., Ohji,S., Ichikawa,N., Kimura,A.,
            Yamazoe,A., Komaki,H., Igarashi,Y. and Fujita,N.
  TITLE     Whole genome shotgun sequence of Streptomyces sp. NBRC 110030
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 625317)
  AUTHORS   Hosoyama,A., Kimura,A., Ohji,S., Ichikawa,N., Yamazoe,A. and
            Fujita,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-NOV-2014) Contact:Director-General Biological Resource
            Center National Institute of Technology and Evaluation, NITE
            Biological Resource Center; 2-49-10 Nishihara, Shibuya-ku, Tokyo
            151-0066, Japan URL :http://www.bio.nite.go.jp/
COMMENT     ##Genome-Assembly-Data-START##
            Finishing Goal                    :: Improved High-Quality Draft
            Current Finishing Status          :: High-Quality Draft
            Assembly Method                   :: newbler v. 2.6
            Genome Coverage                   :: 97x
            Sequencing Technology :: 454 GS-FLX Titanium; Illumina HiSeq 1000
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001417675.1-RS_2024_08_17
            Annotation Date                   :: 08/17/2024 02:44:29
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,240
            CDSs (total)                      :: 7,152
            Genes (coding)                    :: 7,019
            CDSs (with protein)               :: 7,019
            Genes (RNA)                       :: 88
            rRNAs                             :: 6, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1 (5S, 16S)
            partial rRNAs                     :: 4, 5 (16S, 23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 133
            CDSs (without protein)            :: 133
            Pseudo Genes (ambiguous residues) :: 0 of 133
            Pseudo Genes (frameshifted)       :: 45 of 133
            Pseudo Genes (incomplete)         :: 107 of 133
            Pseudo Genes (internal stop)      :: 8 of 133
            Pseudo Genes (multiple problems)  :: 23 of 133
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 21:33:49
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 88372
            Orig. end                         :: 129557
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            BBOK01000004.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..41185
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41185
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41185
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21185](+)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21185
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     misc_feature    complement(522..536)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.02"
                     /tool="antismash"
     gene            complement(1304..1495)
                     /locus_tag="APK71_RS12175"
     CDS             complement(1304..1495)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389857.1"
                     /locus_tag="APK71_RS12175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF2795 domain-containing protein"
                     /protein_id="WP_030398974.1"
                     /transl_table=11
                     /translation="MADLSPIDLQKALNGMDYPADKKALVDCARRNKADDKVVSRLDGL
                     KESSFDGPNEVQKAVFNG"
     gene            complement(1584..3164)
                     /locus_tag="APK71_RS12180"
     CDS             complement(1584..3164)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389856.1"
                     /locus_tag="APK71_RS12180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_107094262.1"
                     /sec_met_domain="DAO (E-value: 2.1e-09, bitscore: 32.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPPPASRTSRSYDAVIVGGGHNGLVAAAYLARAGRSVLVLERL
                     DHTGGAAVSTRPFAGVDARLSRYSYLVSLLPSKIVRDLGLDFRVRARTVSSYTPVERAG
                     RPTGLLVGGGERRTRASFARLTGSDREYAAWQRFYALTGRVAQRVFPTLTEPLPTRDEL
                     RRRVDDEAAWRALFEEPLGVAIEEHFADDLVRGVVLTDALIGTFADAHDPSLAQNRCFL
                     YHVIGGGTGAWNVPVGGMGALTDALADTARAAGAVLATGHEAVRIEADGRTAEVTHRSA
                     DGEYVTAARHVLVNASPRELAALTGQAPPPPAEGAQLKVNMLLTRLPRLRDPGTDPREA
                     FAGTFHIAEGYGQLAAAHAQAAAGELPGAPPSEIYCHSLTDPTILGPGPAAQGMHTLTL
                     FGLHTPARLFARDNDAVRDELLKSTLAQLDAHLAEPLADCLASDADGRPCIEARSPLDL
                     ERDLRLPGGNIFHRELSWPHAQEGTGHWGVETGRANVLLCGAGAVRGGGVSGVPGHNAA
                     MAVLEGAGS"
     gene            complement(3447..4349)
                     /locus_tag="APK71_RS12185"
     CDS             complement(3447..4349)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971907.1"
                     /locus_tag="APK71_RS12185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="oxygenase MpaB family protein"
                     /protein_id="WP_055468102.1"
                     /transl_table=11
                     /translation="MAATRTGGDPGLFGPDSVTWQAHGDPMMWVAGIRALYLQALHPRA
                     VRGVMQNSDFRRDAWGRLMRTAGFVGTTTYGTTEAAERAGARVRKIHRMLGATDPGTGE
                     RYALDEPALLLWVHCAEIGSYLHVLRRSGFPLTDAHADRYLAEHRHSARLVGLGPGSVP
                     ADRAELAAYFARVRPELAAGAEAREVDAFLRRPPVHPLLVPARALLWRRVARLAYDSLP
                     AYAHELYGRPAPPPATVTRRLRVTGTVLRAIPAGVRWQLPPRHILRAVERLGPAARPAP
                     YRIGRQAAILDPPGEGAAD"
     gene            complement(4389..4766)
                     /locus_tag="APK71_RS12190"
     CDS             complement(4389..4766)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971908.1"
                     /locus_tag="APK71_RS12190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="four-helix bundle copper-binding protein"
                     /protein_id="WP_030398971.1"
                     /transl_table=11
                     /translation="MTSTTTSQQELFRFLEDRFACAQACTECARACALRASLVDPDGTE
                     NQELVRRKGIMCAEVCDATCRVLSEQNQVDESAIRAQLEWCRQVCLESAHVFDDHPGAE
                     ESAKACRDCARACGEFLTTLR"
     gene            4923..5327
                     /locus_tag="APK71_RS12195"
     CDS             4923..5327
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446765.1"
                     /locus_tag="APK71_RS12195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ChaB family protein"
                     /protein_id="WP_030398970.1"
                     /transl_table=11
                     /translation="MPGRQELPSTLERSPQEARRTWIEAHDSAVEEYGEGERAHRVAYG
                     ALKHKFEKVGDHWERKEGGRKGPSDPRSGRPRGQGGRSGEGVDEQASKEHLYGVARRLG
                     VEGRSKMSKADLLAAIRKANRSRTRASRSG"
     gene            5365..5718
                     /locus_tag="APK71_RS12200"
     CDS             5365..5718
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031532.1"
                     /locus_tag="APK71_RS12200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6479 family protein"
                     /protein_id="WP_055468103.1"
                     /transl_table=11
                     /translation="MTNAWRDLAAGGSGGFPVWLIIAAVVVVGVLIGAFAFGSRQKRRE
                     PPPPTADEQPRLPDDGPVHEERERREPNEMPRRDERTLPHEMRHQGSRTASDQQRPRWE
                     EGHSGSFGGGGPG"
     gene            5792..7459
                     /locus_tag="APK71_RS12205"
     CDS             5792..7459
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016328000.1"
                     /locus_tag="APK71_RS12205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ubiquinol-cytochrome c reductase cytochrome b
                     subunit"
                     /protein_id="WP_055468104.1"
                     /transl_table=11
                     /translation="MLLQRKRARAGARARHTAEHTVNWADGRLPVSEGGGLLRKAFPEH
                     WSFLLGEIALYSFVVLLLTGVWLTLFFKPSMTEVLYDGSYEPLVGVSMSEAYRSTVDIS
                     FDVRGGLLIRQVHHWAALVFVSAIGVHLLRIFFTGAFRRPREVNWLIGVTLFLLALVEG
                     FAGYSLPDDLLSGTGLRIAQGVLQSVPVVGTYLTMFAFGGQYPGHDIVPRLYSLHILLL
                     PGLLLALVTVHLILVFYLKHTQWAGRGRTNRNVVGKPLFPNFMANSTGLFFTVFGVLTV
                     LAAVAQINPIWTYGPYRPDIISSGSQPDWYVGFLEGSLRLMPPFETAVAGHTVMWNVLV
                     PAVLLPGALFTVLYAYPFFERWVTGDHEEHHLCDRPRDKPVRTGLGVAAIVFYGVLLLA
                     GGNDILAHTFQLSLNLLTWIFRISLVLAPLLAFVVAKRVCLALQERDRERLEEGEETGE
                     VHQTLAGGYAESNGPLDPEERHVLRSRREPEPLAPSPQEGDGPHVGRLRATLSEWYYGD
                     RVDVEGGEPQQGRESALEAASGQPGAPERDAYSGEPER"
     gene            complement(7435..7845)
                     /locus_tag="APK71_RS12210"
     CDS             complement(7435..7845)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0022900 - electron transport chain
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971910.1"
                     /locus_tag="APK71_RS12210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome c oxidase subunit 4"
                     /protein_id="WP_030398967.1"
                     /transl_table=11
                     /translation="MRTESRLFTGVAVFFGGEAALYGWWSREPAGTAALVLAFLMAALV
                     GFFLRVQYHKRGLRAQDRGEGEIVDTAGPLDFFPPHSPWPVTIAFAAVVLAFGIVFGLW
                     LALIGFGLLGMGVCGLVFQYADRGVQRSGSPE"
     gene            complement(7842..9518)
                     /gene="ctaD"
                     /locus_tag="APK71_RS12215"
     CDS             complement(7842..9518)
                     /EC_number="7.1.1.9"
                     /GO_function="GO:0004129 - cytochrome-c oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015990 - electron transport coupled proton
                     transport [Evidence IEA]"
                     /codon_start=1
                     /gene="ctaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327999.1"
                     /locus_tag="APK71_RS12215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cytochrome c oxidase subunit I"
                     /protein_id="WP_051783116.1"
                     /transl_table=11
                     /translation="MAVDRRTQPPRRTPARQRTNRTLGRALVRWATTTDHKVIGHLYLA
                     TSFGFFLFGGVLAMLMRAELARPGLQLFSNEQYNQLFTMHGAIMLLLFATPLFAGFTNA
                     VMPLQIGAPDLALPRLNALSYWLYLFGGLTVAAGFLTPGGAASFGWFAYAPLNSAVFSP
                     GPGGDLWIMGLVLSGVSTTLSAVNFITTILCLRAPGMTMFRMPIFTWNVLFTSILVLPA
                     FPVLTAALLMLEADRKFGAHVFDAANGGALLWQHLFWFFGHPEVYIIALPFFGIVTEII
                     PVFSRKPIFGYVSLIGATIAITMLSAVVWAHHMFATGAVLLPFFSVMSFLIAVPTGVKF
                     FNWTGTMLRGSLSFETPMLWSCGFLVTFLLGGLSGVLIASPPLDFHLTDSYFIVAHLHY
                     VVFGTVVFAMFAGFYFWWPKLTGKMLDERIGKIHFWTLFVGFQTTFLVQHWLGEQGMPR
                     RYADYLAADGFTTLNTVSSLGAFLLGLSTLPFLYNVWHTHHYGRKVEQDDPWGYGRSLE
                     WATSCPPPRHNFTSLPRIRSESPAFDLHHPDVTRHDQRHVQ"
     gene            complement(9672..12473)
                     /locus_tag="APK71_RS12220"
     CDS             complement(9672..12473)
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612146.1"
                     /locus_tag="APK71_RS12220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="S9 family peptidase"
                     /protein_id="WP_055468105.1"
                     /transl_table=11
                     /translation="MIRARTTWAAATAVLTLVGIAPTAAHADPRPPGSSTAPVRTAPKD
                     TAGLPPGWRITGTGAAAALEWRSPRPVPPGDARVEFHTDGSRLGVPRPDDDGRTFRLPL
                     KDVPPAALESPSGLQVRAAGRRLDGEPGAAARERRRAEAPPAKLPPLLPAGSVDPGRPG
                     RFATTTGEYTLDSVKLPGLPAPVEMRGVVVAPEGATGKRPLALFLHGRHATCYVPGQDE
                     ESVTIDWPCADDARPIPSHRGYLQDQKLLASQGYVTVSISANGVNGQDAVVEDGGAQAR
                     SSLVRAHLARWADWAAGTSAAPAAVRQSPKADLSRVLLVGHSRGGEGVARAAMDSLYPP
                     PASQDGRPGRARWTVRGTVLVGPTAFGQNPVPDVPSLTVLPGCDGDVSDLQGQLYVDGT
                     RGVSRGRALHSAVHITGANHNYFNSEWTPGLAEAPASDDFWEDPGSPDPVCSAGSATRL
                     TAAQQHRAGATYVAAAARLFVAGDDRVRELIDGTGRRAPSADPARVLTHAVGAGRGAGF
                     LPDDGVRVTGGRLCSAVDPDPAVACLDEDTQGASPHFAYWWPERETGRGAVALDWTAPG
                     TATRVRPRAPLSLKGADSLALRVIVPPGSTGTRLDVSVTDAAGRRATLGSVRADGLPGS
                     ERTASYWAQELRVPLTAAGRAGVDLRRVTALELTPRSRAGRAWLMDAHAWHPGTPRVRP
                     APLARVDVGRTTVEEGDSGVRTYHVPVRVSGKGTGTVRMYVMAPDGGAEERLVTVRSGR
                     PFADVAVKVTGNTRYGGDTSHDLLVKAVHGTVVGSYSGGVTVEEDDPMPEISVTPVADE
                     VTEGQALRWRVSLSEPADVDLGTVLVAVPDDTRPELSTKDVDHDWLLERAGEVPDGEVP
                     LSRLDWFVLWAAVPAGETDTEVTVPTVTDEVAEPTEYIGLRGTDDWGRPQGPLLTGAVL
                     DAP"
     gene            complement(12609..13331)
                     /locus_tag="APK71_RS12225"
     CDS             complement(12609..13331)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446757.1"
                     /locus_tag="APK71_RS12225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_234319709.1"
                     /transl_table=11
                     /translation="MNPSARPRTAAPAPRTRPRDGRPGRGARRALPVVLAALLPLAACG
                     IPETGVVEAGEPATGVLQPGVTAVPSETAPEAVPLVKVPLYFVEDGALTAVSRTVAAPG
                     DLGSTVLMLFKGPDAQERGRGLTTELPPAAVAPTIRTDGTAVTVQLPRTAAGLSDTAVD
                     QLACTVAVARLRQDPALGSAQVTVEQPGGRLAGRSSDDCPSGAARPSGAPAETAAAPDP
                     EAGRGTGGSVGGIGPTGG"
     gene            complement(13328..14839)
                     /locus_tag="APK71_RS12230"
     CDS             complement(13328..14839)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019327255.1"
                     /locus_tag="APK71_RS12230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_053665672.1"
                     /transl_table=11
                     /translation="MLRALVGLRLRLVVAFTLVAVVATVTTGALTFREARTGVLQQSQD
                     TVIEEFRHRVNTLVPNYRFPPEPADLQSFADDVSRGGRSQPWRVLVAYRDASATSVPDD
                     RFAELSSAMRESVRSRRATVFQRVSHDGRSALVVGMPVTFAGQYSTERRASGLEVYLTV
                     PQQEEQGYVDALVSAIERATVPALVLAVLIALLAARGVLRPVRALRRATRSIAEGRLDT
                     RLAVQGSDELADLSRTFNETAAALEGSVAELRRMEAGARRFAADVSHELRTPLAAMSAV
                     TDVLDEDAAGLDDDTATAVRLISTETSKLAALVDDLMEISRFDAGAAALHLDEIDLAES
                     LRRTLASRGWQDTVETALPGPGELRGRVDPRRLDVIVANLVANALRHGAPPVRLDLRVQ
                     DDPTAGRQAVVTVRDGGDGIPESVLPHVFDRFYKSADARARSEGSGLGLAIATENVRLH
                     DGTVRAANHPGGGAVFTVVLPLPPDDTEERTTTHQDPNPPTEART"
     gene            complement(14851..15540)
                     /locus_tag="APK71_RS12235"
     CDS             complement(14851..15540)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446760.1"
                     /locus_tag="APK71_RS12235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_030398962.1"
                     /transl_table=11
                     /translation="MPRVLIIEDDRAVRDGLLLALRRQGHEVAAAATGEDGLEQLRSFR
                     PEAVVLDLMLPGMSGLEVCRRIRAHDQLPIIMATARGDDTDIVVGLESGADDYVVKPVR
                     ARVLDARIRAVLRRVGSTSDDPATPRPEHHGDLVIDRAGLTVTHQGRPVALGPSELRLL
                     LTLSASVGQVFSRQQLLEAVWEHNYHGDARLVDACVKRLRSKIGEVPGSPRYVHTVRGF
                     GYRFGPR"
     gene            15654..16568
                     /locus_tag="APK71_RS12240"
     CDS             15654..16568
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031527.1"
                     /locus_tag="APK71_RS12240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF3152 domain-containing protein"
                     /protein_id="WP_031081303.1"
                     /transl_table=11
                     /translation="MNERRRPTPPPSSATGRRRRGGRARRRRGGRSRLLWPGLAAGAVL
                     VLAGGLAFKGATEPTGHSADAAGAPSPTQSGGTKEARKDAPSPPPEKDEEEKGAGEDVE
                     KRTDEKPDPGSIPSSGPGTFATAGGGGDRVGGSGRTLTYVVQVEDGIGIPAREVAAEVE
                     RVLADERGWTADGKVGFRRVTGGTSDFRVRLATASTVDDICGRYGLDTGGEVNCNVGQD
                     VMVNLKRWLLATQYYADDVTSYRALIINHEVGHFLGHGHEGCPGAGRPAPVMMQQIKGL
                     HGCRTNVWPYDAEGRPVTGPALR"
     gene            complement(16573..17598)
                     /locus_tag="APK71_RS12245"
     CDS             complement(16573..17598)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016327994.1"
                     /locus_tag="APK71_RS12245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SPFH domain-containing protein"
                     /protein_id="WP_030398960.1"
                     /transl_table=11
                     /translation="MEASAFLIAGVIVALLAVFTVVRAVRIVPQARARNVERLGRYHRT
                     LKPGLSVVIPYIDRVYPVIDLREQVVSFKPQPVITEDNLVVEIDTVLYFQVTDPRAAFY
                     EIANFLQAVEQLTVTTLRNVVGSMDLEKTLTSRDTINSQLRGVLDEATGKWGLRVNRVE
                     IKAIDPPQSIKDAMQKQMRAERDKRAAILGAEGQRQSQILTAEGDKQAAVLRAEGNRTA
                     EILKAEGQSRAIDEVFQAVHRNDPDPKLLAYQYLQVLPQLAQGSGSTFWVIPSEVTSAL
                     QGVSRAFTEALPQSPATREHPSDDGAAQAASDTAQAAEAAAQALADAARANGVPPEGHA
                     A"
     gene            complement(17601..18032)
                     /locus_tag="APK71_RS12250"
     CDS             complement(17601..18032)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388222.1"
                     /locus_tag="APK71_RS12250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NfeD family protein"
                     /protein_id="WP_031081301.1"
                     /transl_table=11
                     /translation="MDPWLIWLIVSAVMIVAEIFTLTTALGMLGVAALITSASAAAGLS
                     TPFQFLVFTVVSAVTLLFLRPVAVRHLHQPQTERFGVEALVGQAAYVVSDVTGRDGRVR
                     IGGEEWSARSYDETLVIPRGATVDVLEISGTTAFVYPRE"
     misc_feature    complement(18051..18064)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.76"
                     /tool="antismash"
     misc_feature    18051..18067
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 21.43"
                     /tool="antismash"
     misc_feature    18052..18065
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 16.37"
                     /tool="antismash"
     gene            complement(18182..18913)
                     /locus_tag="APK71_RS12255"
     CDS             complement(18182..18913)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031524.1"
                     /locus_tag="APK71_RS12255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="WP_055468106.1"
                     /transl_table=11
                     /translation="MRTKRRVAVAVGALVAPLLAVSLPASTAGAHGWVTSPGSRQDQCA
                     AGVVDCGQIKYEPQSVEGPKGLKSCSGGNSQFAELDDDSKGWRVTPVGTTHTFTWHHTA
                     RHATATWQYFIGDQKIAEFDGRGAQPAPDVSHQVDFGGFTGRQKVLAVWNVADTGNAFY
                     SCIDVNIGGTGGDGGGGDGGSGEPGTCDAPVWSAGSVYGGGDTVSHGGHHWRAKWWVTG
                     EEPGTTGEWGVWEDLGACAAA"
     misc_feature    complement(18931..18946)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.69"
                     /tool="antismash"
     misc_feature    18952..18967
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 23.76"
                     /tool="antismash"
     misc_feature    19088..19103
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: medium, score: 22.47"
                     /tool="antismash"
     gene            19249..19704
                     /locus_tag="APK71_RS12260"
     CDS             19249..19704
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388250.1"
                     /locus_tag="APK71_RS12260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DoxX family protein"
                     /protein_id="WP_030398957.1"
                     /transl_table=11
                     /translation="MEALEKRREHVIALFRIVTGLLFACHGAATLFDVLGGPHGAAPGF
                     AAWPGWWAAVVQLVGGTLVLCGLATRAAAVLCSGSMAYAYFVEHQPDGLFPIENGGESA
                     AMFCWSFLLVAAVGPGRWSLASRLRPRRGEDDRPVTASLPTDTPTSA"
     misc_feature    19781..19796
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     gene            20001..21185
                     /locus_tag="APK71_RS12265"
     CDS             20001..21185
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024: chalcone and stilbene synthase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031521.1"
                     /locus_tag="APK71_RS12265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyketide synthase"
                     /protein_id="WP_107094263.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 2.9e-18,
                     bitscore: 61.3, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAYLCPPAVIHGAHSVHTREIVAEVHDRHPDAAWAPRAEGIAAS
                     TGIETRGWMLPLEAAVAPGNGSGAGPAGPGSAREALLRDGFTERDADRVIAALEAVPAP
                     QTVQERTAPAWEAVQAYGERAARGALQIAGLDVADVDCLITSNSTTPALPGLDVSLANR
                     LPLRGDTMLLPAAQWACVAGTRSLALAADLVAADPDRVVLVVISEALSTTYQPADDTLE
                     SLIVRLLFADTAVAAVVTGRPRPESVLRLDASWHHTLPGTRDLHRLETRADGTHFVMDR
                     RGPRAVQETVAAMWEWLRVRHEDDPRSWHPDLLLAHPGGTRVLEYMEQTMPGEWPSGLL
                     RHSRDSYTTGNRGGAAVFDILRRAHDAGQKAGSRAVLYAAAPGLTATALEGEWL"
     gene            21370..23529
                     /locus_tag="APK71_RS12270"
     CDS             21370..23529
                     /EC_number="3.1.3.16"
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971925.1"
                     /locus_tag="APK71_RS12270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_030398955.1"
                     /transl_table=11
                     /translation="MDSTPPSSSSSRFDLVSSALGRYLPHDRAAGPGPADSPADPAGHP
                     PEHDRHAAGRPEQILGAVNLDRELRVTHRNLDAPVFAGLDAVIGRPFVDLLPQGDVPTV
                     TRRLRQVLETGEAHVARVQRLRRTDGSELVVSMSILPAAAPREGLTVSVIAMARRLHLY
                     AAETAIGTSLDIGETAQSLAESLLAWGDVAAIDLDFAVWTGERVTDRAQDRIRLRRAAL
                     VPDRAWPEGYVTLGEDLPSEASRLLARAIRRADAPRSIVLPDRAAIERVLGSPRLVRAL
                     VPGERSAGVACVPLVLEGDPPVVLGVAEVWRRADRPFADSELFDLQELVARTSHHVDLA
                     RQHQREHTQVLALQRRLLPRSGGGTVETASVYQPTTPDSAGVGGDWVNSFPLPDGRTAL
                     VVGDVVGHGLGAAATMGQLSMEARALLSAGLAPDEVLEHLDETVTLLDDTDSGLAAGYS
                     ALGSTCCIAVYDPVGHRLALSNAGHLPPILVSPDGRAGALPVHPHPGLGAEFALREPFG
                     VHTFAAPPGSLLALYTDGLVEDPALPIDEGIGRLTEAVAAVHPWDALQQAARKVVSEVM
                     PAHRRDDVTLLLARTIGHRKGDTATWRLPAREDAAARARALVSALLRQWDTRDATRDKV
                     LLLVSELVTNAVRHAGGPITVRLIRAGHGLLCEVGDTGNGRPRLGRGRTLDDRGRGLHV
                     VHRLTTRWGVRWTESGKVVWAEVAR"
     gene            23634..24260
                     /locus_tag="APK71_RS12275"
     CDS             23634..24260
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971926.1"
                     /locus_tag="APK71_RS12275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_055468108.1"
                     /transl_table=11
                     /translation="MTGTATRYLCLARHGEASPEGTELTAAGRRQATLLGRRLRGIPFA
                     AFHHGPLPRARQTARLVAGELTGVTPCVSEAAGDYLPHVPERAELPPESADHCLRFLAG
                     VTDEERERGAELARQALRRFTGPVTDGPEDRHELVVTHNFLVGWLVRDALYAPKWRWLG
                     LNHGNAALTVIRYAPGRAASVLVSNDMRHLPPELRWTGFPREEHV"
     gene            complement(24314..24577)
                     /locus_tag="APK71_RS12280"
     CDS             complement(24314..24577)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="APK71_RS12280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_055468109.1"
                     /transl_table=11
                     /translation="MKAPARGRRCTPARRGRASRDVGDTTAGHKRRFLKSSEPLADVSA
                     VRNGRNGRNDWIVTLDSVDLVESSRDPAAVGFLAAVLRGHGS"
     gene            complement(24574..25959)
                     /locus_tag="APK71_RS12285"
     CDS             complement(24574..25959)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (105-422). E-value:
                     1.3e-22. Score: 72.3. Matches aSDomain:
                     nrpspksdomains_APK71_RS12285_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012382.4"
                     /locus_tag="APK71_RS12285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="WP_053639791.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.3e-21, bitscore:
                     72.3, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGEAERVARLLGAWRTDQPVRTALRDALAELVDGAHLPPGWRMP
                     GQRDLAEALGVARGTVARAYADLVADGRLAPRHGSGTYVRGARGAARPGEGRLTSFDGA
                     RPVVDLSSGALPGSDLVADVMPEVGRLLRDHLRGPGYHPAGLPELRQALAADFTRRGVP
                     TREDEVVITAGSQQAVWLIATALTGPGTLTLVEDPSYRGALEAFAGAGGRVQGVRFTSA
                     GLDLDLLARAGAGADLLYVQTALHNPTGVHTPGPRRRALGELAARHGLLVVDDQSQADL
                     GWHRSQPLPGLDQHTDPAGLLTVGTLSKLFWGGIRVGWVRGPRELVGRLVEVRRAVDLG
                     SPVADQLAALLLLPRAAEQREHRRAFLLRHAADTEEVLRATLPHWRWQPPAGGSGLWID
                     TGGNAVRLSGRALERGLRLTPGPAFSPHHSHDRYVRLPVWLPHSTVLDVARTLAGLCAP
                     REE"
     aSDomain        complement(24694..25644)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS12285_Aminotran_1_2.1"
                     /evalue="1.30E-22"
                     /label="APK71_RS12285_Aminotran_1_2.1"
                     /locus_tag="APK71_RS12285"
                     /protein_end="422"
                     /protein_start="105"
                     /score="72.3"
                     /tool="antismash"
                     /translation="PVVDLSSGALPGSDLVADVMPEVGRLLRDHLRGPGYHPAGLPELR
                     QALAADFTRRGVPTREDEVVITAGSQQAVWLIATALTGPGTLTLVEDPSYRGALEAFAG
                     AGGRVQGVRFTSAGLDLDLLARAGAGADLLYVQTALHNPTGVHTPGPRRRALGELAARH
                     GLLVVDDQSQADLGWHRSQPLPGLDQHTDPAGLLTVGTLSKLFWGGIRVGWVRGPRELV
                     GRLVEVRRAVDLGSPVADQLAALLLLPRAAEQREHRRAFLLRHAADTEEVLRATLPHWR
                     WQPPAGGSGLWIDTGGNAVRLSGRALERGLRLTPGP"
     gene            26075..27298
                     /locus_tag="APK71_RS12290"
     CDS             26075..27298
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565366.1"
                     /locus_tag="APK71_RS12290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Tm-1-like ATP-binding domain-containing protein"
                     /protein_id="WP_055468110.1"
                     /transl_table=11
                     /translation="MATVVLLGTLDTKGAEYAWLAERLRGHGVDVVTVDVGPLSDAAAD
                     VTAAEVARAAGADLAALRAAGDRGRAMEAMAAGAARTVTGLHAAGRLDGVLAVGGSGGT
                     SVASRAVQELPVGVPKLLVSTMAAGDVTPYVGAVDVTLMYAVVDVAGINSLSEQVFGNA
                     AAGVSAMAREYARRRAAPATGHRPLVGLSMFGLTTPAVDEAREELDRLGYEPLVFHATG
                     AGGRTLEKLAGDGRFAGVLDLTTTELADDLVGGVLSAGPGRLEAAGARGVPQVVSPGAL
                     DMVNFGPRATVPARFDDRTFVVHNPTVTLMRTTPAENAELGRRIGAKLAAARGPVTVFL
                     PLRGVSGVDRDGGPFRDAEADAALFAALREALAGSAVEVVEDDAHINDPGFGRRAAHRL
                     HELITAGR"
     gene            27377..28246
                     /locus_tag="APK71_RS12295"
     CDS             27377..28246
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018565367.1"
                     /locus_tag="APK71_RS12295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphoenolpyruvate hydrolase family protein"
                     /protein_id="WP_053639793.1"
                     /transl_table=11
                     /translation="MDRATALRRLRETVASGRPVIGGGAGTGISAKSAEAGGIDLLIIY
                     NSGRYRMAGRGSLAGLLAYGDANAIVMEMADEVLPVVRDTPVLAGVNGTDPFRVMGRFL
                     DRLKEAGFTGVQNFPTVGLIDGVFRQNLEETGMGFGHEVEMIAAAHERDLLTAPYVFDP
                     DQAAAMAEAGADVLVPHLGLTTKGTIGATTALGLDECVDRIQAMRDAAVQVNPDIMVLC
                     HGGPIAEPGDAQYVLSRTRGVVGFFGASSIERLPTETGIRRQTEAFKSLALPAAESGGP
                     GSGTSPRG"
     gene            complement(28973..29938)
                     /locus_tag="APK71_RS12300"
     CDS             complement(28973..29938)
                     /NRPS_PKS="Domain: PKS_ER (23-318). E-value: 1.6e-40.
                     Score: 131.1. Matches aSDomain:
                     nrpspksdomains_APK71_RS12300_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979476.1"
                     /locus_tag="APK71_RS12300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_055468111.1"
                     /sec_met_domain="ADH_N (E-value: 2.7e-07, bitscore: 25.6,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 7.7e-14, bitscore:
                     47.0, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDDRMMKAVLYDRYGGPDVLYTGRVPRPEPAPGEILVKVRAFSVN
                     GGELAARAGRLRLLTGRKFPKRVGLDFTGEVAALGAGVTRCAAGDRVWGVLGRTSGFGS
                     AAEYVTVPTERVGRVPDGLDLVDAAALPVATTAITALRDKAGLRPGERLLVRGAAGGVG
                     NAAVQLGRAYGAEVTALARAANLDFVRGLGAHKAVDHRSVRPAELGRFDVVVDTAGTDL
                     RAFRRLLNPGGRMVTIAFDLKRPAASLGYLAASTVHGHGRVRFFSGNPTRADFDDLARH
                     VAQGKLSPAVDTVFPLEETAAAHHALEAGGVQGKYVVRVA"
     aSDomain        complement(28985..29869)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS12300_PKS_ER.1"
                     /evalue="1.60E-40"
                     /label="APK71_RS12300_PKS_ER.1"
                     /locus_tag="APK71_RS12300"
                     /protein_end="318"
                     /protein_start="23"
                     /score="131.1"
                     /tool="antismash"
                     /translation="RVPRPEPAPGEILVKVRAFSVNGGELAARAGRLRLLTGRKFPKRV
                     GLDFTGEVAALGAGVTRCAAGDRVWGVLGRTSGFGSAAEYVTVPTERVGRVPDGLDLVD
                     AAALPVATTAITALRDKAGLRPGERLLVRGAAGGVGNAAVQLGRAYGAEVTALARAANL
                     DFVRGLGAHKAVDHRSVRPAELGRFDVVVDTAGTDLRAFRRLLNPGGRMVTIAFDLKRP
                     AASLGYLAASTVHGHGRVRFFSGNPTRADFDDLARHVAQGKLSPAVDTVFPLEETAAAH
                     HALEAGGVQGKYVV"
     CDS_motif       complement(29432..29491)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS12300_0002"
                     /evalue="4.00E-06"
                     /label="PKSI-ER_m5"
                     /locus_tag="APK71_RS12300"
                     /protein_end="169"
                     /protein_start="149"
                     /score="19.4"
                     /tool="antismash"
                     /translation="GERLLVRGAAGGVGNAAVQL"
     CDS_motif       complement(29525..29566)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_APK71_RS12300_0001"
                     /evalue="6.00E+01"
                     /label="PKSI-ER_m5"
                     /locus_tag="APK71_RS12300"
                     /protein_end="138"
                     /protein_start="124"
                     /score="-3.1"
                     /tool="antismash"
                     /translation="LVDAAALPVATTAI"
     gene            30040..30720
                     /locus_tag="APK71_RS12305"
     CDS             30040..30720
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003979477.1"
                     /locus_tag="APK71_RS12305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_055468112.1"
                     /transl_table=11
                     /translation="MTEASRITARDGMRADARRNRERVLVAARAVFAEHGIDAPMATVA
                     RRAGVGVATLYRHFPTRDALVRGAFAQQMETCARALTEALADPDPWQGFQQLVETICAL
                     QREERGFPAAFAAAFPDSTSEHAPYRQRAERDFTTLVRRAQASGALRADFHPSDLAVAL
                     LAHCGLVTALPDDGAASRRLVAYLLQSFRTDPANKPLPPPTALTLRSFPIATDSPQGQR
                     SSRA"
     misc_feature    30803..30818
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.68"
                     /tool="antismash"
     gene            30849..31274
                     /locus_tag="APK71_RS12310"
     CDS             30849..31274
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062556.1"
                     /locus_tag="APK71_RS12310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_079080563.1"
                     /transl_table=11
                     /translation="MNTKLRYGCLGLLVVTALYTGAWAYFAPESWHENFPGFGLSWLPR
                     LGPYNEHLAKDTGAMFLALAALTLIALRDVRDNRLVRITGAVWLVFNVLHFSYHVQHLG
                     MYGTRDQVLNVLSLSALVLVSVLLLVPLGPVRRNGTR"
     gene            31271..32077
                     /locus_tag="APK71_RS12315"
     CDS             31271..32077
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062555.1"
                     /locus_tag="APK71_RS12315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_234319708.1"
                     /transl_table=11
                     /translation="MTYENTTEARIGVRIAVAGGTGLVGRLVVEEVTAAGHEPVVLARS
                     RGVDLTTGAGLDAALRGAEAVIDVSNLTTTSAKKSCAFFERVSRELLDAGARAGVGHHV
                     ALSIVGIDRVGMGYYQGKLRQEDVVRNGATPWTVLRATQFHEFAQQTLDRVPRPLAVVP
                     RMRTQPVAAREVAQHLVRLALAPAQGMAPDLAGPAVEQLVDLTRRLLRARNERRLLLPV
                     TFPGAAGRAMKGDGLLPTGRGPRGSQTFDAWLAHHVADTAPAAGRG"
     gene            32085..33029
                     /gene="sigJ"
                     /locus_tag="APK71_RS12320"
     CDS             32085..33029
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene="sigJ"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524473.1"
                     /locus_tag="APK71_RS12320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="RNA polymerase sigma factor SigJ"
                     /protein_id="WP_055468113.1"
                     /transl_table=11
                     /translation="MPTPSDAESGSDSALTLHSLLAERRHLLNLGYRMLGSVQEAEDVV
                     QETYARWYALSEEGREAIAAPEAWLTRVASRICLDHLASARMRRERYTGEWLPEPVRHS
                     ATWSSTDAAHAGDPADRITLDESVSMGMLVVLETITPAERVAFVLHDVFGVPFTEIAET
                     VGRTPAACRQLASSARRRLARERTGGSTTPEHRRVVSAFREACETGDLGALVDLLDPGV
                     KSRSDGGGKVRAALRPVLGQDKVARLVLGLLRQEPEVELVEDDVNGAPGLSVRIAGTTV
                     AVLSMGIRDGLIADLWLVVNPDKLRAWTRYGTE"
     misc_feature    complement(33123..33138)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            33806..34915
                     /locus_tag="APK71_RS12325"
     CDS             33806..34915
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1282:
                     extracellular ligand-binding receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435902.1"
                     /locus_tag="APK71_RS12325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_055468114.1"
                     /transl_table=11
                     /translation="MNTPPSPSGAEHTDGSSIRLGALVPLTRPGWVEAGRHLLAGLDLA
                     VREVNDAGGIDGRPLELVVRDTAADPERAAAAVDELAHLGVTAVVGEYHSVVARAAAAR
                     ADALGVPFLCSSAVLDTLTEEPTEWVARLAPAQSYGWRIYADFLLRSGRRRIAVVTQPS
                     VYWASGTRVLRDHLAPRGGTVLELDATLTPEALCDALVDDGATALLLLVGHPEPAVPIV
                     RAVRGDRRLAEILVGAPAGQPEFAEWAAALGEDGAGVPFLRYLPERLGPLGERVGKELR
                     ERLGEAPSFVAFEGWDTVAVLAAVLRSHGTDRAAIAESWPRVAVEGTRRPIRFSRTPGI
                     SVWQWAWTPVQVVDRDPAEPDRFRILHVG"
     misc_feature    35474..35489
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     misc_feature    complement(35562..35574)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            35636..37729
                     /locus_tag="APK71_RS12330"
     CDS             35636..37729
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1035: MMPL domain-containing transport protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016828332.1"
                     /locus_tag="APK71_RS12330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MMPL family transporter"
                     /protein_id="WP_234353166.1"
                     /transl_table=11
                     /translation="MLGTTASSLSPGGYNSVGTESAHADGLLRKFRGDDPGLVLRVRSE
                     DSVDSARARSDGAALARRVAAQPGVAAVEAYWTSRSPALRANDGRSALIGVALEGDEAA
                     QARAASRLVPRVTGRQGALRVSAGGRVWAGIQAAEQGERDLVRAELVVAPVVFGCLVFA
                     FGSLLAALFPLLVGALAVAGSWAFLRLLGGVTEVSAISLNIAATLGFGLAVDYALLVVT
                     RFREEGARGLAVPDAAVRAARTAGRSVLVSAGVVALAFSALWVFPFPWLRSMAVAGIAV
                     VLLAATATVVLVPALLAMLGSRIRHRRAASSPAWRRLVRWVTGSPWLWGACCAVLMAAL
                     VWPFGQAQWGFTDERALPAGSQARQFTERLRTDFPAQPDRDLIVVLTPVPGDREVDQYA
                     RRISALPGVVQVTAPTGRYHDRRRTAVVEAVSDSATAVWLKASTGLDPQSAQAARLVER
                     VRELPPPGPRWVGGSPARHVDAKAALAGRVPWAVLLMSATTLTALLLYTRSVLIPLKAV
                     ALAALSLTASLGSMVYIFQEGHLRWLVGDFTTTGFLDMTIPPLLCAIAFALSLDYEVFL
                     LARVKEHYDAGGDHRDAIVEGVARTGRLITVAAVVFAVSMAGLASSGITTLKMMGVGLG
                     VAVLVDATLVRGILVPAFMQLTGRANWWAPAWVRRPATQEAHAPQHGRDTVAESSAEAP
                     AAH"
     gene            complement(37747..38580)
                     /locus_tag="APK71_RS12335"
     CDS             complement(37747..38580)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016828331.1"
                     /locus_tag="APK71_RS12335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_234319706.1"
                     /transl_table=11
                     /translation="MTLGYLFVAATAVVLGQEAVPHAAWLTGAYAALAGFVLACAAAHR
                     HWASPALANVRALYPLACAPLLFSASGPQSLALHGRLLDDTMLVWEQHLFGAHPNLLLG
                     ALASRPLTEALSLSYSSYYLYFVLPPAYFLAKGMHQALHRYVLGLCLAHYLCFLGFMLL
                     PLAGPVAALAPAFTPDHLHGYLAQPLQAQLMASADPPGTCFPSSHVAGAWAAALSIRGA
                     SVPRPAKRLMIAATALITVSVVYCRYHYVLDAAAGMATAALAVFLTRRLTRRESN"
     misc_feature    complement(38890..38900)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            39035..40129
                     /locus_tag="APK71_RS12340"
     CDS             39035..40129
                     /NRPS_PKS="Domain: Aminotran_1_2 (3-342). E-value: 1e-50.
                     Score: 164.8. Matches aSDomain:
                     nrpspksdomains_APK71_RS12340_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004993543.1"
                     /locus_tag="APK71_RS12340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_234353167.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.3e-50, bitscore:
                     164.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAINAASGDYLGLAADPRVREAAAAAARELGASCSGSPAVIGTW
                     SVHAQLAEELADFLHRPAVLLSTTGYQANLTLACLFGEDRAVVADRHIHASLVDALRLG
                     PAKYRRFRHNAPDHLARLLEEASGQGLSPVVLTEGAFSLGGELAVLPEIADLAGRHGGM
                     LIVDGAHDIGILGPSGRGAGEHLGCEQDIDVLSGTFSKAFGAGGGYLAGSTELIEHCRL
                     LGRATMYSASMPPPTAAAALRALRIIRDEPEQRAVLARLAGRLHDGLAEVGYDRPNWAS
                     PVVTLPAGDADQCLRTWRAMLEAGVFAAPFLPPAAPAGQSLLRLSVTAAHTEAHIDHIL
                     EVVGRLVPTVDTTGVAAAPIPCPA"
     aSDomain        39044..40060
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_APK71_RS12340_Aminotran_1_2.1"
                     /evalue="1.00E-50"
                     /label="APK71_RS12340_Aminotran_1_2.1"
                     /locus_tag="APK71_RS12340"
                     /protein_end="342"
                     /protein_start="3"
                     /score="164.8"
                     /tool="antismash"
                     /translation="INAASGDYLGLAADPRVREAAAAAARELGASCSGSPAVIGTWSVH
                     AQLAEELADFLHRPAVLLSTTGYQANLTLACLFGEDRAVVADRHIHASLVDALRLGPAK
                     YRRFRHNAPDHLARLLEEASGQGLSPVVLTEGAFSLGGELAVLPEIADLAGRHGGMLIV
                     DGAHDIGILGPSGRGAGEHLGCEQDIDVLSGTFSKAFGAGGGYLAGSTELIEHCRLLGR
                     ATMYSASMPPPTAAAALRALRIIRDEPEQRAVLARLAGRLHDGLAEVGYDRPNWASPVV
                     TLPAGDADQCLRTWRAMLEAGVFAAPFLPPAAPAGQSLLRLSVTAAHTEAHIDHILEV"
     misc_feature    complement(40386..40401)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.3"
                     /tool="antismash"
ORIGIN
        1 cttcggccgg gccggcaagc aggacgtgac gatccgtcac ctgctcacgc acacctccgg
       61 cttccgggcc tggatcgcgc tgtacggcgc gcccacccac gaggagaagg tgcggctggt
      121 ctacgacgag gcgccggtga acgcccccgg cacggcgtac ctgtactcgg acctgaacat
      181 gatctcgctc cagtgggtgc tcgagaaggt cacgggccgc accctggacg tgctgctgcg
      241 cgacgggatc acccggccgc tcggtctcgg ccgcacccgt tacaacccgc ccgcttcctg
      301 gcggccgggg atcgcggcca ccgaggacgc ccgccggccc tggtccggcc tggaccgcgg
      361 gctggtgtgg ggcgaggtgc acgacgagaa cgccttcggc ctgggcgggg tggccggcca
      421 cgccggggtg ttctccaccg cgtgggacct cgcggtcctc ggccgcaccc tcctcaacgg
      481 cggttcctac ggccgggcgc gcatcctgcg gccggagtcg gtggagctga tgttcaccga
      541 cttcaacacc gacttcccgg gcgacgagca cggcctgggc ttcgagctgt accagcactg
      601 gtacatgggc gcgatggcga cgccgcgcac ggccgggcac accggtttca cgggcacctc
      661 gctggtgctc gacccgacga ccggctcctt cctcgtcgtg ctcggcaact ccgtccatcc
      721 ggtccgcagt tggcgttccg gctcggctcc ccgggtggcg gcgggcacca gcctggcgcg
      781 ggcggtgccg gtacggcccg cgcacggtcg caccgcctgg ttctcgggga cggcgagttc
      841 cacggcggcc acgctgacgc tgcccgcgct ggacacgtcg gccgggcggg cgaggctgcg
      901 ctgctcgctg tggtgggaca ccgaaccggg gtcggacgcc ctggtcctgg agtcctccgc
      961 cgacggcggc gcgtcgtggc agccggtgcc gttcaccacc gtccggcccg gcgaggcacc
     1021 ccgggagcat ccggagggct cggccaccgg ctggtcgggg cgcgtctggc accggctgag
     1081 cgccggcctg ccggccgcac gcgggctcac cctgcgctgg cggtacacga ccgaccggct
     1141 gtacgtgggc cgcggggcgt acgtcgacgg ggtgcgggtg gaggccgacg gctccgtcct
     1201 gttccacgac gcgcgcccgg cggacgcggc gcgcgtcgag gcggcgggct ggtcggcgtc
     1261 cgccgactga cctgcgggcc ggcggggcgc cggcgcgggg ccgctagccg ttgaagacgg
     1321 ccttctgcac ctcgttcgga ccgtcgaagc tgctctcctt cagtccgtcg agacggctca
     1381 cgaccttgtc gtcggccttg ttcctgcggg cgcagtcgac gagcgccttc ttgtcggccg
     1441 ggtagtccat gccgttgagg gccttctgca ggtcgatggg gctgaggtcc gccatgacgg
     1501 gctccttgtc gcgtgggggt gacatacgga atgtccgtca tgtcgcggta cccagcgcgg
     1561 tgcgggacat gcgcacgtgg ccgtcagctc ccggccccct ccagcaccgc catcgccgcg
     1621 ttgtgtcccg gcaccccgct cacccctccc ccgcgcacgg cgcccgcgcc gcacagcagg
     1681 acgttggccc ggccggtctc caccccccag tggccggtgc cctcctgggc gtggggccag
     1741 gacagctcgc ggtggaagat gttcccgccg ggcaggcgca ggtcgcgttc caggtcgagc
     1801 ggcgacctgg cctcgatgca gggccgcccg tccgcgtcgc tcgccaggca gtcggcgagc
     1861 ggctcggcca ggtgggcgtc gagctgggcg agggtcgact tcagcagttc gtcgcgtacg
     1921 gcgtcgttgt cccgggcgaa gaggcgggcg ggggtgtgca ggccgaacag ggtgagggtg
     1981 tgcatgccct gcgcggccgg gccgggaccg aggatcgtcg ggtcggtcag tgagtggcag
     2041 tagatctcgg agggcggggc gccgggcagt tccccggcgg ccgcctgggc gtgcgcggcg
     2101 gccagttgcc cgtacccctc ggcgatgtgg aaggtgccgg cgaaggcctc gcgcgggtcg
     2161 gtgccggggt cgcgcagccg cgggagccgg gtcagcagca tgttgacctt gagctgggcg
     2221 ccctctgcgg gcgggggcgg cgcctgcccg gtgagcgccg ccagttcccg cggggaggcg
     2281 ttgaccagga cgtggcgggc ggcggtcacg tactcgccgt cggccgagcg gtgggtgacc
     2341 tcggccgtgc ggccgtcggc ctcgatccgt accgcctcgt gtccggtggc gagcacggca
     2401 ccggcggcgc gggccgtgtc cgccagcgcg tcggtgaggg cgcccatgcc gccgacgggc
     2461 acgttccagg cgccggtgcc gccgccgatc acgtggtaga ggaagcagcg gttctgggcc
     2521 agggaggggt cgtgggcgtc ggcgaaggtg ccgatcaggg cgtcggtgag gacgacgccc
     2581 cggaccaggt cgtcggcgaa gtgctcctcg atcgcgacgc cgagcggctc ctcgaacagg
     2641 gcccgccagg ccgcctcgtc gtcgaccctg cggcgcagct cgtcgcgggt gggcaggggc
     2701 tcggtgaggg tcgggaagac ccgctgtgcg acacggccgg tcagggcgta gaagcgctgc
     2761 caggccgcgt actcccggtc ggagccggtg agccgggcga aggacgcccg cgtgcgccgt
     2821 tcgcccccgc cgacgagcag cccggtgggc cgcccggcgc gctcgacggg cgtgtacgag
     2881 gagacggtgc gggcgcgcac ccggaagtcc aggccgaggt cccgcacgat cttgctcggc
     2941 agcaggctga ccaggtacga gtagcgcgac agccgcgcgt ccaccccggc gaacggccgc
     3001 gtggacaccg cggccccgcc ggtgtggtcc agccgctcca gcaccagcac ggagcgtccg
     3061 gcccgggcca ggtaggcggc ggcgaccagg ccgttgtgac caccaccgac gatgacggcg
     3121 tcgtagctgc gggaggtacg ggaagcaggg ggcggggtcg tcatggccct tggtaacacg
     3181 accggatccg aggctgccag cccacggccg gccgccgtcc ggacggccgg ggcgccgccc
     3241 ggcaccccgg ggcgggcgtc cagagtccgg cctgcggcca ggtggcgtct tccgacgccc
     3301 cggggcaggc gtcccggggc cggcctgcga ccaggcagca ccgcccgacg cctccgagca
     3361 ggcgaccccg gcccagcctc cgaccagcag ccggtaccgg ccctggatca gcgtgctgtc
     3421 ccccatgact tcgccgcccc cgtggttcag tccgccgcgc cctcccctgg cgggtccagt
     3481 atggccgctt gtcggccgat tctgtatggc gccggacgcg cggccgggcc gagccgctcc
     3541 acggcacgca ggatgtgccg gggcggcaac tgccagcgca cccctgcggg gatcgcgcgc
     3601 agcacggtgc cggtgacgcg cagccggcgg gtgacggttg cgggcggggg cgcggggcgg
     3661 ccgtagagct cgtgcgcgta cgcgggcagc gagtcgtacg cgagccgggc gaccctccgc
     3721 cacagcaggg cgcgggccgg gaccaggagg gggtgcaccg gcgggcggcg caggaaggcg
     3781 tcgacctcgc gggcctccgc cccggccgcc agttcgggcc ggacccgcgc gaagtaggcg
     3841 gccagctcgg cgcggtcggc gggtacggag ccggggccga ggccgaccag gcgggcgctg
     3901 tgccggtgtt cggcgaggta gcggtcggcg tgggcgtcgg tgagggggaa cccggagcgg
     3961 cgcagaacgt gcaggtagga accgatctcg gcgcagtgca cccacagcag cagcgcgggt
     4021 tcgtcgaggg cgtagcgctc gcccgtgccg gggtcggtgg cgccgagcat gcggtggatc
     4081 ttccgcaccc gggcgccggc ccgctcggcg gcctcggtgg tgccgtacgt cgtggtgccg
     4141 acgaagcccg cggtgcgcat cagccggccc caggcgtcgc gccggaagtc gctgttctgc
     4201 atcactccgc gcacggcgcg cgggtgcagg gcctggaggt acagggcgcg gatgccggcc
     4261 acccacatca tcgggtcgcc gtgcgcctgc caggtcacgg agtccggtcc gaagagcccc
     4321 ggatcgcctc cggtccgcgt cgccgccaca ggggcagact aacgcggcgc gggccccgct
     4381 cccaggggtc agcgcagggt ggtcaggaac tctccgcagg cgcgggcgca gtcgcggcag
     4441 gccttcgcgc tctcctcggc gcccgggtgg tcgtcgaaga cgtgggcgct ctccaggcac
     4501 acctggcggc accactccag ttgggcgcgg atggcggact cgtccacctg gttctgttcg
     4561 gacagcaccc ggcaggtcgc gtcgcagacc tccgcgcaca tgatgccctt gcgccgcacg
     4621 agttcctggt tctcggtccc gtccgggtcc acgaggctcg cccgcagggc acaggcccgg
     4681 gcgcactcgg tgcacgcctg tgcgcacgcg aagcggtcct cgaggaagcg gaacagttcc
     4741 tgctgggaag tcgtcgtcga tgtcacaccg cgcgggttgc cgccggcggc ggtgccaaac
     4801 cgcgcggccc ggtcccggca agggttccgg gccgttttcc gggacggacg gcagggcacc
     4861 cgtggaccgc ccccgcgacc gccgggggcc acgacagcga ggacgcacgg aggtgcacgg
     4921 acatgccggg acgacaggaa ctgccgtcga ccctggaacg ctctccgcag gaggcccggc
     4981 gcacctggat cgaggcccac gactcggccg tcgaggagta cggcgagggc gagcgggccc
     5041 accgggtggc gtacggggcg ctcaagcaca agttcgagaa ggtcggcgac cactgggagc
     5101 gcaaggaggg cggacgcaag gggccctccg acccccggtc cgggcggccc cgcggtcagg
     5161 gcggccgcag tggcgagggc gtcgacgagc aggcctcgaa ggagcacctg tacggcgtcg
     5221 cccggcgcct gggcgtcgag ggccggtcga agatgtcgaa ggcggacctg ctcgcggcga
     5281 tcaggaaggc caaccggtcg cggacgcggg cgtcgcggtc ggggtgagca ggttggcggc
     5341 gcgggcccgg ggtacccgcg cgccatgacc aacgcatgga gggacctggc agcgggcgga
     5401 tccggcggct tccccgtctg gctgatcatc gcggccgtcg tggtggtggg cgtgctgatc
     5461 ggagccttcg ccttcggcag ccggcaaaag cgccgggagc cgccgccgcc gacggccgac
     5521 gagcagccgc gtctgccgga cgacgggccc gtccacgagg agcgggagcg ccgggaaccg
     5581 aacgagatgc cgcggcgcga cgagcgcacc ctgccgcacg agatgcggca ccagggcagc
     5641 cgtaccgcct ccgaccagca gcgcccccgc tgggaggagg gccacagcgg ctcgttcggc
     5701 ggcggcggcc cgggctgacc ccggtgccgg agggtgaccg gaggcggccg gtgcgtagtt
     5761 tccggtacgg cccccgggga acccatgcgc cgtgctgctg cagaggaaga gggcccgcgc
     5821 cggtgcgcgg gcccgtcaca cggccgaaca caccgtcaac tgggccgacg ggcggctccc
     5881 cgtctccgag ggcggggggc tgctgcgcaa ggccttcccc gagcactggt cgttcctgct
     5941 gggcgagatc gccctgtaca gcttcgtcgt cctgctgctg accggggtct ggctgacgct
     6001 gttcttcaag ccctcgatga cggaggtcct ctacgacggc tcgtacgaac ccctggtggg
     6061 cgtgagcatg tcggaggcct accgctcgac ggtggacatc agtttcgacg tgcgcggcgg
     6121 gctgctgatc cggcaggtgc accactgggc ggcgctggtg ttcgtgtccg ccatcggagt
     6181 gcacctgctg cggatcttct tcaccggggc cttccgccgg ccgcgcgagg tcaactggct
     6241 gatcggtgtc acgctgttcc tgctggccct cgtcgagggc ttcgccggct actccctccc
     6301 cgacgacctg ctctccggca cggggctgcg catcgcgcag ggggtcctgc agtccgtccc
     6361 ggtggtgggg acgtacctga ccatgttcgc gttcggcggc cagtatcccg gccacgacat
     6421 cgtcccgcgg ctgtactcgc tgcacatcct gctgctgccc gggctgctgc tggcgctggt
     6481 cacggtccac ctgatcctgg tgttctacct caagcacacc cagtgggcgg ggcgcgggcg
     6541 caccaaccgc aacgtggtgg gcaagccgct gttcccgaac ttcatggcga actcgacggg
     6601 cctgttcttc acggtcttcg gtgtgctgac ggtgctcgcg gcggtggcgc agatcaaccc
     6661 gatctggacg tacggcccgt accgcccgga catcatctcc tcgggttccc agccggactg
     6721 gtacgtcggc ttcctggagg gctcgctgcg gctgatgccc ccgttcgaga cggcggtggc
     6781 gggccacacc gtgatgtgga acgtcctggt gcccgccgtc ctgctgccgg gcgccctgtt
     6841 cacggtgctg tacgcgtacc cgttcttcga gcggtgggtg accggcgacc acgaggagca
     6901 ccatctgtgc gaccggcccc gggacaagcc cgtgcggacc gggctgggcg tcgccgcgat
     6961 cgtcttctac ggggttctgc tcctggccgg cggcaacgac atcctggccc acacgttcca
     7021 gctctcgctg aacctgctga cctggatctt ccggatctcc ctggtgctgg cgccgctgct
     7081 cgccttcgtc gtggccaagc gggtctgcct ggccctgcag gagcgcgacc gcgagcgtct
     7141 ggaggagggc gaggagacgg gcgaggtgca ccagaccctc gccggcggct acgccgagag
     7201 caacgggccc ctcgaccccg aggagcgcca tgtgctgcgt tcccgccggg aacccgagcc
     7261 gctggccccg tcgccccagg agggcgacgg cccgcacgtg ggacggctgc gggcgacgct
     7321 cagcgagtgg tactacggcg accgggtcga cgtcgagggg ggcgagccgc agcagggccg
     7381 ggagtcggcg ctcgaagcgg cgtcggggca gcccggggcc ccggagcggg atgcctactc
     7441 gggcgagccg gagcgctgaa cgccccggtc ggcgtactgg aagaccaggc cgcagacgcc
     7501 catgccgagc aggccgaagc cgatcagtgc cagccacagg ccgaagacga tgccgaaggc
     7561 gagcaccacg gcggcgaacg cgatggtgac cggccagggg ctgtgcggcg ggaagaagtc
     7621 gagcggtccg gccgtgtcga cgatctcgcc ctcgccgcgg tcctgcgcgc gcaggccgcg
     7681 cttgtggtac tgcacccgca ggaagaagcc gacgagcgcg gccatcagga aggcgaggac
     7741 gagcgcggcc gtgccggcgg gctcgcgcga ccaccagccg tagagggccg cctcgccgcc
     7801 gaagaagacc gcgacaccgg tgaacagacg ggattcggtc ctcactgcac atgcctctga
     7861 tcgtgtcggg tgacgtcggg gtggtggagg tcgaaggccg gggactcgga gcggatccgg
     7921 ggcagcgacg tgaagttgtg gcgcggcggc ggacaactgg tggcccattc gagggaacgg
     7981 ccgtagcccc aggggtcgtc ctgctcgacc ttcctgccgt agtggtgggt gtgccacacg
     8041 ttgtagagga acggcagggt ggacagaccg agcaggaagg cgccgaggga gctgacggtg
     8101 ttcagcgtgg tgaagccgtc cgcggccagg tagtcggcgt agcggcgcgg catgccctgc
     8161 tcgccgagcc agtgctggac gaggaaggtg gtctggaagc cgacgaagag cgtccagaag
     8221 tggatcttgc cgatgcgttc gtcgagcatc ttgccggtca gcttcggcca ccagaagtag
     8281 aagccggcga acatcgcgaa gacgaccgtg ccgaagacca cgtagtgcag gtgcgcgacg
     8341 atgaagtacg agtccgtcag gtggaagtcc agcggcgggg aggcgatcag gaccccgctc
     8401 aggccgccga gcaggaacgt caccaggaag ccgcacgacc acagcatggg cgtctcgaag
     8461 gacagcgagc cgcgcagcat cgtgccggtc cagttgaaga acttcactcc ggtcggtacg
     8521 gcgatgagga acgacatgac ggagaagaag gggagcagca cggcgcccgt ggcgaacatg
     8581 tggtgggccc acaccaccgc ggagagcatg gtgatggcga tggtcgcgcc gatgaggctg
     8641 acgtagccga agatcggctt gcggctgaag accgggatga tctcggtgac gatgccgaag
     8701 aacggcagcg cgatgatgta cacctcggga tgcccgaaga accagaacag gtgctgccac
     8761 agcagggccc cgccgttggc cgcgtcgaag acgtgcgcgc cgaacttccg gtcggcctcg
     8821 agcatcagca gcgcggcggt gaggacgggg aaggcgggca ggaccaggat cgacgtgaac
     8881 agcacgttcc aggtgaagat cggcatccgg aacatggtca tgccgggggc gcgcaggcac
     8941 aggatggtgg tgatgaagtt gacggcgctg agcgtggtcg acacaccgct cagcaccagg
     9001 cccatgatcc acaggtcgcc ccccggaccg gggctgaaga ccgcgctgtt caggggggcg
     9061 taggcgaacc agccgaacga ggccgctccg ccgggggtca ggaaccccgc cgccaccgtc
     9121 agtccgccga acaggtacag ccagtacgag agcgcgttga gccggggcag cgcgaggtcc
     9181 ggggcaccga tctgcaacgg catcacggcg ttggtgaacc cggcgaacag cggggtcgcg
     9241 aacagcagca gcatgatggc gccgtgcatg gtgaagagct ggttgtactg ctcgttgctg
     9301 aacaactgca gccccgggcg ggcgagttcc gcgcgcatca gcatggcgag gacgccgccg
     9361 aagaggaaga agccgaacga cgtcgccaag tagagatggc cgatcacctt gtgatcggtc
     9421 gtggtcgccc accgcaccag agcccgcccg agcgtgcggt tcgtccgctg ccgagccggt
     9481 gtccggcgcg gcggctgggt ccttctgtcc accgccatgc ggcggagggt acccaggggc
     9541 catgggccca gacgtacgac gcggccgggg ccggcgccgg gtgtccggcg gatgggccac
     9601 ccggcgtgcg cgggcgcgga acggacggtg ccgcttccgc acccgcgggg ccggggtgac
     9661 gggacgccgg gttacggggc gtcgagcacg gcgccggtca gcagcggacc ctgcggcctg
     9721 ccccagtcgt cggtgccccg cagaccgatg tactcggtcg gttcggcgac ctcgtcggtg
     9781 acggtgggca ccgtcacctc ggtgtccgtc tcaccggccg gcacggcggc ccagagcacg
     9841 aaccagtcca gccgggagag cggcacctca ccgtcgggga cctcccccgc cctctcgagg
     9901 agccagtcgt ggtcgacgtc cttggtggac agctcgggac gggtgtcgtc gggaaccgcc
     9961 accagcaccg tgcccaggtc cacgtcggcg ggttccgaca gcgagacccg ccagcgcagc
    10021 gcctgcccct cggtgacctc gtcggccacc ggcgtcacgc tgatctccgg catcgggtcg
    10081 tcctcctcga ccgtcacacc gcccgagtag gacccgacga cggtgccgtg cacggccttg
    10141 accagcaggt cgtggctcgt gtccccgccg taccgcgtgt tgccggtcac cttcacggcc
    10201 acgtcggcga agggacggcc ggagcgcacg gtgaccaggc gctcctcggc cccgccgtcc
    10261 ggtgccatga cgtacatgcg gaccgtgccg gtgcccttgc cggagacccg caccggcacg
    10321 tggtacgtgc gcacgccgga gtcaccctct tcgacggtgg tccggccgac gtcgacacgg
    10381 gccagcgggg ccggtcgcac ccgtggtgtg ccggggtgcc aggcgtgggc gtccatcagc
    10441 caggcccggc ccgcgcggga acgcggtgtc agttccagcg cggtgacgcg gcgcaggtcc
    10501 actccggcgc ggccggcggc ggtgagcggt acgcgcagtt cctgcgccca gtaggacgcg
    10561 gtgcgctcgc tgcccggcag gccgtcggcg cggacgctgc cgagggtggc gcgccggccg
    10621 gcggcgtcgg tgacggacac gtcgagccgg gtgccggtgc tgccgggcgg cacgatgacg
    10681 cgcagggcga ggctgtcggc gcccttcagc gagagggggg cgcggggccg gacgcgggtc
    10741 gcggtgccgg gcgcggtcca gtccagggcg accgcgccgc ggcccgtctc ccgctccggc
    10801 caccagtacg cgaagtgcgg cgaggcgccc tgcgtgtcct cgtcgaggca ggcgacggcc
    10861 gggtcggggt cgaccgcgga gcacaggcgt ccgccggtca cccgcacacc gtcgtcgggc
    10921 aggaatccgg cgccgcggcc ggcgccgacc gcgtgggtca gcacccgggc cgggtcggcc
    10981 gagggggcgc ggcgtccggt gccgtcgatc agttcgcgca cccggtcgtc accggcgacg
    11041 aacagccggg cggccgcggc gacgtaggtg gcgccggccc ggtgctgctg cgcggcggtg
    11101 agccgggtcg cgcttccggc ggagcagacc gggtcggggg acccggggtc ctcccagaag
    11161 tcgtcggagg cgggggcctc ggcgaggccg ggcgtccact cgctgttgaa gtagttgtgg
    11221 ttggcgcccg tgatgtggac cgcgctgtgc agcgcccggc cccggctgac gccgcgggtg
    11281 ccgtcgacgt agagctggcc ctggaggtcg gagacgtcgc cgtcgcagcc cggcaggacg
    11341 gtcagggacg gcacgtcggg caccgggttc tggccgaagg cggtggggcc gaccagtacg
    11401 gtgccgcgga cggtccagcg ggccctgccc ggccggccgt cctggctcgc gggcggcggg
    11461 tagaggctgt ccatggcggc ccgggcgacg ccttcgccgc cgcgggagtg gccgacgagc
    11521 agcacgcggg acaggtcggc cttcgggctc tggcggacgg cggccggggc ggcggaggtg
    11581 ccggccgccc agtcggccca gcgggccagg tgcgcgcgca ccagcgacga gcgggcctgg
    11641 gcgcccccgt cctcgaccac ggcgtcctgg ccgttgacgc cgttggcgga gatcgagacg
    11701 gtcacgtagc cctgggaggc cagcagcttc tggtcctgga gatagccgcg gtggctgggg
    11761 atgggccggg cgtcgtccgc gcagggccag tcgatggtga cggactcctc gtcctggccg
    11821 gggacgtagc aggtggcgtg gcggccgtgc aggaagagcg cgagggggcg tttgccggtc
    11881 gccccctcgg gcgcgacgac cacgccgcgc atctcgaccg gtgcgggcag cccgggcagc
    11941 ttgacggagt cgagcgtgta ctcgccggtg gtggtggcga accggccggg gcggcccggg
    12001 tccacggagc ctgcggggag caggggcggc agcttcgccg ggggcgcctc ggcgcggcgg
    12061 cgttcgcggg cggcggcgcc cggttccccg tccaggcggc ggcctgcggc gcggacctgg
    12121 agaccggacg ggctctccaa cgcggccggc gggacgtcct tgaggggcag gcggaaggtc
    12181 ctgccgtcgt cgtccggtcg cggtacgccg aggcgactgc cgtcggtgtg gaactccacc
    12241 cgtgcgtcgc cgggcgggac gggacgcggg gagcgccact ccagggcggc ggccgcaccg
    12301 gtgccggtga tccgccagcc cggcggcagg ccggcggtgt ccttcggggc cgtccgtacc
    12361 ggtgcggtgc tgctgccggg cggacgcggg tcggcgtggg ccgcggtggg ggcgatgccg
    12421 acgagggtca gtacggctgt cgctgcggcc catgtggttc gagcacgtat caagaatcgg
    12481 ctcctcaaca cctcggccgt ggctcggtcg tgccacggtt cgggggcgcc cgcccgtgcg
    12541 ggcgccccct ggtgggagga ggggaaggag atcccccggg ttgcctgtga gccgtcaacc
    12601 gcccttcttc agccgccggt tggcccgatt ccgccgacgc tcccgccggt gccccggccg
    12661 gcttcggggt ccggggccgc ggcggtctcg gcgggggcgc cggacgggcg ggccgcgccg
    12721 gacgggcagt cgtcgctgga gcggccggcc agtcggccgc cgggctgctc gacggtcacc
    12781 tgcgcgctcc ccagcgccgg gtcctgccgc agccgggcga cggcgaccgt gcaggccagt
    12841 tggtcgacgg ccgtgtcgct caggcccgcg gcggtccgcg gcagttggac ggtgaccgcc
    12901 gtgccgtcgg tgcggatggt gggggccacg gcggcgggcg gcagctcggt cgtcagcccc
    12961 cgcccccgct cctgggcgtc cggccccttg aacagcatga ggacggtgct gccgaggtcg
    13021 ccgggggccg ccacggtgcg ggacaccgcc gtcagggcgc cgtcctcgac gaagtagagc
    13081 gggaccttga ccaggggcac cgcctcgggt gcggtctccg acggcacggc cgtgacgccc
    13141 ggctgcagga cgccggtcgc gggttcgccc gcctcgacca caccggtctc ggggatgccg
    13201 caggcggcga gggggagcag cgccgcgagg acgacgggga gcgcacgccg ggcaccgcgg
    13261 ccgggacggc cgtcgcgcgg acgcgtgcgc ggggccgggg cggcggtccg cgggcgcgcc
    13321 gaggggttca tgtccgggcc tccgtcggcg ggttcgggtc ctggtgggtg gtcgtccgct
    13381 cctccgtgtc gtccggcgga agcggcagga cgaccgtgaa gacggcaccg cccccgggat
    13441 ggttggcggc gcgcaccgtg ccgtcgtgca ggcgtacgtt ctccgtggcg atggccagcc
    13501 cgaggccgct gccctcgctc cgggcgcggg cgtcggccga cttgtagaag cggtcgaaga
    13561 cgtggggcag gacgctctcg gggatgccgt ccccgccgtc gcggaccgtg acgacggcct
    13621 gcctgccggc ggtcgggtcg tcctggacgc gcaggtccag gcggaccggg ggcgcgccgt
    13681 gtctcagggc gttggcgacg aggttcgcca cgatcacgtc caggcggcgc gggtcgaccc
    13741 ggccgcgcag ttcccccggt cccggcaacg ccgtctccac ggtgtcctgc cagccgcggg
    13801 aggcgagcgt gcggcgcagg gactcggcga ggtcgatctc gtccaggtgc agggcggcgg
    13861 cgcccgcgtc gaaccgggag atctccatga ggtcgtccac gagagcggcc agcttgctgg
    13921 tctcggtgct gatgaggcgt acggccgtcg cggtgtcgtc gtccaggccg gccgcgtcct
    13981 cgtccagcac gtccgtgacc gccgacatcg ccgccagcgg ggtccgcagt tcgtgggaga
    14041 cgtccgcggc gaagcgccgg gcgccggcct ccatgcgccg cagttccgcc accgagccct
    14101 ccagtgccgc ggcggtctcg ttgaacgtgc gggagaggtc ggccagttcg tcggacccct
    14161 gcaccgcgag ccgggtgtcc aggcggccct cggcgatgct gcgggtcgcc cggcgcagcg
    14221 cccgcaccgg ccgcaggacg ccgcgggcgg cgaggagcgc gatcagtacg gccaggacca
    14281 gcgccggcac ggtggcacgt tcgatggcgc tgaccagcgc gtcgacgtaa ccctgctcct
    14341 cctgctgcgg cacggtgagg tagacctcga gtccggaggc gcgccgctcg gtgctgtact
    14401 ggccggcgaa ggtcacgggc atgccgacca ccagcgcgga tcggccgtcg tgcgacacgc
    14461 gctggaacac ggtggcccgg cgggagcgca cggactcgcg catcgccgag gacagttcgg
    14521 cgaagcggtc gtcggggacg gaggtcgcgc tcgcgtcccg gtaggcgacc agcacccgcc
    14581 agggctggga ccgtccgccc ctggatacgt cgtcggcgaa ggactggagg tcggccggct
    14641 cgggcgggaa acggtagttg gggacgaggg tgttgacccg gtgccggaac tcctcgatca
    14701 ccgtgtcctg gctctgctgc aggaccccgg tccgggcctc gcggaaggtc agcgcgccgg
    14761 tggtcaccgt ggccacgacg gcgacgaggg tgaaggccac cacgagcctg aggcgcagcc
    14821 ccaccagtgc gcgcagcacc cgcggcaccc tcaccggggg ccgaaccggt agccgaagcc
    14881 gcgcacggtg tggacgtagc gcggactgcc cggcacttcc ccgatcttgg accgcagccg
    14941 cttgacacag gcgtccacga gccgcgcgtc cccgtggtag ttgtgctccc acacggcctc
    15001 caggagctgc tgacggctga acacctgccc gacggaggcg gacagggtga gcagcagccg
    15061 cagttcggag gggccgaggg cgaccggccg tccctggtgg gtgacggtca gtccggcccg
    15121 gtcgatgacc aggtccccgt ggtgctcggg gcgcggcgtg gccgggtcgt cggacgtgct
    15181 gcccacgcgg cgcagcacgg cgcgtatgcg tgcgtccagg acgcgggcgc ggaccggctt
    15241 gaccacgtag tcgtcggctc cggactccag tccgaccacg atgtcggtgt cgtcgccgcg
    15301 ggcggtggcc atgatgatcg ggagctggtc gtgggcgcgg atgcgacggc acacctccag
    15361 gccggacatg cccggcagca tcaggtcgag gaccacggcc tcgggccgga acgaccggag
    15421 ctgttccagg ccgtcctcgc ccgtcgcggc ggcggcgacc tcgtgcccct gtcggcgcag
    15481 ggcgagcagc aggccgtccc ggacggcgcg gtcgtcttcg atgatcagga cccgtggcat
    15541 ggacctcagt atgcgtgtgc gcgggcgggg gccggcccgc gggtgagggc tgttacacag
    15601 cggtccacca ggcgtccacg cgccatcaca cgccgggagc acgctgtgtg atcatgaacg
    15661 agcgccgccg accgactccc ccaccctcct ccgccacggg ccgccggcgc cgtggcggcc
    15721 gtgcccgccg ccgacggggc ggccggtccc gcctgctgtg gccggggctc gcggccgggg
    15781 ccgtcctggt gctcgccggg ggcctggcgt tcaagggggc cacggagccc accggccact
    15841 ccgccgacgc cgccggcgcg ccctcgccga cgcagagcgg cggcacgaag gaggcccgga
    15901 aggacgcgcc ctcgcccccg ccggagaagg acgaggagga gaagggcgcc ggggaggacg
    15961 tggagaagcg gacggacgag aaaccggacc ccggatcgat accgtcgtcc gggcccggga
    16021 ccttcgccac cgccggcggg ggcggcgacc gggtcggcgg cagcggacgg accctgacct
    16081 acgtggtgca ggtcgaggac ggcatcggga tcccggcacg ggaggtcgct gccgaggtcg
    16141 agcgcgtcct cgccgacgag cggggctgga cggccgacgg gaaggtgggc ttccggcggg
    16201 tgaccggcgg gacgtccgac ttccgggtgc ggctcgccac ggcgtcgacg gtggacgaca
    16261 tctgcggccg gtacggcctg gacaccgggg gcgaggtcaa ctgcaacgtg ggccaggacg
    16321 tgatggtcaa cctcaagcgg tggctgctgg cgacgcagta ctacgcggac gacgtgacgt
    16381 cgtaccgcgc gctgatcatc aatcacgagg tcgggcactt cctcggccac ggtcacgagg
    16441 ggtgtccggg agcggggcgt ccggctcccg tgatgatgca gcagatcaag ggactgcacg
    16501 gctgccggac caatgtctgg ccctacgacg ccgagggccg gcccgttacg ggaccggccc
    16561 tgcgctgagt gctcacgccg cgtggccctc ggggggcacg ccgttggccc tggccgcgtc
    16621 ggcgagggcc tgggcggcgg cctccgcggc ctgtgccgtg tcgctggccg cctgggcggc
    16681 cccgtcgtcg gacgggtgct cccgggtggc cggcgactgg ggcagcgctt cggtgaaggc
    16741 ccgggacact ccctggagcg cggaggtgac ctcgctgggg atgacccaga acgtgctgcc
    16801 ggagccctgt gccagctggg gcagcacctg gaggtactgg taggccagca gcttggggtc
    16861 ggggtcgttg cggtggacgg cctggaagac ctcgtcgatg gcccgggact ggccctccgc
    16921 cttgaggatc tcggcggtgc ggttgccctc ggcgcgcagg acggcggcct gcttgtcgcc
    16981 ctcggccgtg aggatctgcg actggcgctg gccctccgcg cccaggatgg cggcccgctt
    17041 gtcccgctcg gcgcgcatct gcttctgcat cgcgtccttg atggactgcg gcgggtcgat
    17101 cgccttgatc tccacccggt tcacccgcag cccccacttg ccggtggcct cgtcgagcac
    17161 cccgcgcaac tggctgttga tggtgtcgcg cgaggtgagg gtcttctcca ggtccatcga
    17221 gcccacgacg ttgcgcaggg tggtgacggt gagctgctcg accgcctgga ggaagttcgc
    17281 gatctcgtag aaggccgcgc gggggtcggt gacctggaag tacagcacgg tgtcgatctc
    17341 gacgaccagg ttgtcctcgg tgatgaccgg ttgcggcttg aaggagacga cctgttcacg
    17401 caggtcgatc accggataga cgcggtcgat gtacgggatg accacgctca gtccgggttt
    17461 cagggtgcgg tggtagcggc ccagccgttc gacgttgcgg gcacgggcct gcggcacgat
    17521 gcgcaccgcc cgcaccacgg tgaaaacggc gagaagcgcg acgatcacac cggcgatgag
    17581 gaacgccgag gcttccatgg tcactcccgg gggtagacga atgcggtggt gccgctgatc
    17641 tccagaacgt cgacggtcgc accccgggga atcaccagcg tttcgtcgta ggaacgggcc
    17701 gaccattcct caccgccgat acgcaccctg ccgtcccttc ccgtgacgtc ggagacgacg
    17761 taggcggcct ggcccaccag ggcttccacg ccgaaacgct cggtctgggg ctggtgcagg
    17821 tggcgcaccg cgacggggcg caggaaaagg agggtgaccg cggagacgac cgtgaacacc
    17881 aggaattgaa aaggagtgga aaggccggcc gccgcggatg ccgacgtgat cagcgcggcc
    17941 acgccgagca ttccgagtgc ggtggtcagg gtgaagatct ccgccacgat catcacggcg
    18001 gaaacgatca gccagatcag ccacggatcc attgcgaccc cctttccgct ttgaaattat
    18061 tttaccggct ttcgggaaaa gcggacccgg tcgtgggcgg ggatcgtcgg gccgccggcg
    18121 ggggccggcg cgcaccccgg gcggtgcgcg ccggccggtc gcggtcacgc ggccgggagg
    18181 gtcacgccgc cgcgcaggct cccaggtcct cccagacgcc ccactcaccg gtggtgccgg
    18241 gttcctcgcc ggtcacccac cacttggcgc gccagtggtg gccgccgtgg gagacggtgt
    18301 cgccgccgcc gtagacgctg ccggcgctcc acaccggcgc gtcgcaggta ccgggctcgc
    18361 cgcttccgcc gtcgcccccg cccccgtcgc cgccggtccc gccgatgttg acgtcgatgc
    18421 aggagtagaa cgcgttgccg gtgtccgcca cgttccagac cgccagcacc ttctggcggc
    18481 cggtgaagcc gccgaagtcc acctggtggc tcacgtccgg tgcgggctgc gcgccgcggc
    18541 cgtcgaactc ggcgatcttc tggtcgccga tgaagtactg ccaggtggcg gtggcgtgcc
    18601 gcgccgtgtg gtgccaggtg aaggtgtgcg tcgtaccgac cggggtgacc cgccagccct
    18661 tgctgtcgtc gtcgagttcg gcgaactggc tgtttccgcc gctgcagctc ttcaatccct
    18721 tgggcccctc gacgctctgg ggctcgtact tgatctgccc gcagtcgacg acccccgcgg
    18781 cgcactggtc ctgccggctg ccgggcgagg tcacccatcc gtgggcgccg gccgtgctcg
    18841 ccgggaggct gacggcgagc agcggtgcga ccagcgcccc gaccgcgacg gccacccgtc
    18901 tcttcgtgcg catctcgtgc ccctttcgct acaggtctag acctggcaag ttcaggtcta
    18961 gaccatagcg gggaagccgg tgcggtcaag gggtcgcgcg ccctcaaccc ccggacgggg
    19021 gtgcgcatca accgacggac gagagtgccc acttgacgcg acgacaccga gtgcgactcg
    19081 ttgggctatt ggtctagaca agggtggggg cgatggttaa aagtcgaatg ggccgcgcgt
    19141 ctctcccccc tccctcggga cgccgtcgtg ccccgccccg tgctgcgcac catccccacc
    19201 ggccgcccgg tccccccgcg gccgttgcgc aagagaggag caccaccgtt ggaagcgttg
    19261 gagaaacgca gggagcacgt gatcgcgctc ttccgcatcg tcacaggcct gctgttcgcc
    19321 tgccacggag ccgccaccct gttcgacgtc ctgggcggac cgcacggagc cgcacccggc
    19381 ttcgccgcgt ggccgggctg gtgggccgcc gtggtgcagc tcgtcggcgg caccctggtc
    19441 ctgtgcggcc tcgccacccg cgccgcggcc gtcctgtgct ccgggtcgat ggcgtacgcc
    19501 tacttcgtcg agcaccagcc cgacgggctc ttccccatcg agaacggcgg ggagtcggcg
    19561 gccatgttct gctggtcctt cctgctggtc gccgccgtcg ggccgggccg ctggagcctc
    19621 gcctcccgcc tgcgcccccg gcggggcgag gacgaccggc cggtcaccgc gtcgctgccc
    19681 accgacacgc cgacgtcggc ctgagcgggc ggggcgtgcc gtccacgccg acggtcggca
    19741 cgccccgccc cccgcccgga caccgggccg cctccgcgcg tgtgcgccgt ctcacgcatg
    19801 ccgaggccgt ccgcgttgcg tgggtcactg cgcaattgcc cttttcgcgt ccatgctcgt
    19861 aggagagcac acgccgcccg aagtggcgtg cgccgacgac gacttggtcg cgacgcaccg
    19921 aagcgggcca cgccgcagca cgcgtggcgc cgctccgtcg ccgccggctc agcgcagacc
    19981 cccgcagaaa ggtgccgacc gtggccgcat acctgtgccc tcccgccgtg atacacggcg
    20041 cgcactccgt gcacacccga gagatcgtgg cggaggtgca cgaccggcac ccggacgcgg
    20101 cgtgggcacc acgggccgag ggcatcgcgg cgagcacggg gatcgagacc cgcggctgga
    20161 tgctgccgct ggaggccgcc gtcgcgcccg gcaacgggag cggcgcggga ccggccggcc
    20221 ccgggtccgc ccgggaggcg ctgctccgcg acgggttcac cgagcgggac gcggaccgcg
    20281 tgatcgccgc gctcgaggcc gtaccggcac cgcagaccgt gcaggagcgc accgctccgg
    20341 cctgggaggc cgtgcaggcc tacggggagc gtgcggcgcg cggggccctg cagatcgccg
    20401 ggctggacgt cgcggacgtc gactgcctga tcaccagcaa ctccaccacc ccggcactgc
    20461 cgggactgga cgtctccctg gccaaccggc ttccgctgcg cggcgacacc atgctgctgc
    20521 cggccgcgca gtgggcctgc gtggccggga cccgttcgct ggcgctggcg gcggacctgg
    20581 tggcggcgga ccccgaccgg gtggtcctgg tcgtgatctc cgaggccctg agcacgacct
    20641 accagcccgc ggacgacacc ctggagtccc tgatcgtccg gctgctgttc gccgacaccg
    20701 ccgtcgccgc ggtggtcacg ggccgcccga ggcccgagtc ggtgctccgg ctggacgcct
    20761 cctggcacca caccctgccg ggcacgcggg acctgcaccg tctggagacg cgggcggacg
    20821 gcacccactt cgtgatggac cggcgcgggc cgcgggcggt gcaggagacg gtcgccgcga
    20881 tgtgggagtg gctccgggtc cgccacgagg acgacccccg ctcctggcac cccgacctgc
    20941 tgctcgcgca ccccggcggc acccgcgtgc tggagtacat ggagcagacg atgcccgggg
    21001 agtggccgtc gggactcctg cgccacagcc gggacagcta caccaccggc aaccgcggcg
    21061 gcgccgccgt cttcgacatc ctgcgccggg cccacgacgc gggccagaag gcgggcagcc
    21121 gtgccgtcct gtacgcggcg gccccgggcc tgacggccac cgccctggaa ggcgagtggc
    21181 tgtaaggccc ccccccggga cgggaaccgg tcaccgtccg tggccgcccc gcggtccgca
    21241 ggggtgggcg aagcgtccgc gggtgttatt gaatggggtg tgcggtcggg gtactcgggg
    21301 ctcttccgca cgggttcggg cacggccccg gcactgtgcc agggttggcg agtgagctga
    21361 gggagccgca tggactccac acccccctct tcgtcctcgt cgcggttcga cctggtcagc
    21421 agcgccttgg ggcgctacct cccccacgac cgggcggcag ggcccggccc cgccgattcg
    21481 cccgccgacc ccgcggggca cccgccggag cacgaccgcc acgcggcggg ccggcccgag
    21541 cagatcctcg gtgcggtcaa cctcgaccgg gagctgagag tcacccaccg caacctcgac
    21601 gcccccgtct tcgccggact ggacgcggtg atcggcagac cgttcgtcga cctgctgccg
    21661 cagggggacg taccgacggt cacccgccgg ctgcgccagg ttctggagac cggtgaggcg
    21721 cacgtcgccc gggtgcagcg cctgcggcgc accgacgggt cggagctggt cgtctcgatg
    21781 agcatcctgc ccgcggcggc tccccgggag gggctgaccg tctccgtgat cgcgatggcc
    21841 aggaggctgc acctgtacgc cgccgagacc gcgatcggca cctccctgga catcggcgag
    21901 acggcgcagt cgctcgcgga gtccctgctg gcctgggggg acgtggccgc catcgacctc
    21961 gacttcgccg tgtggacggg cgagcgcgtc accgaccggg cgcaggaccg catccggctg
    22021 cgacgggcgg cgctggtgcc ggaccgggcg tggcccgagg ggtacgtcac cctgggcgag
    22081 gacctcccga gcgaggcgag ccggctgctg gcgcgggcga tacggcgtgc cgacgcaccg
    22141 cggtccatcg tcctccccga ccgcgccgcg atcgagcgcg tgctcgggag tccgcgactg
    22201 gtgcgggccc tggtgcccgg ggaacgttcg gcgggggtgg cctgcgtgcc gctggtcctg
    22261 gagggcgatc cgcccgtcgt cctgggcgtg gcggaggtct ggcggcgggc ggaccggccc
    22321 ttcgccgaca gtgagctgtt cgacttgcag gaactggtgg ccaggacctc ccaccacgtg
    22381 gacctggccc gtcagcacca gcgcgagcac acacaggtgc tggccctgca gcgccggctg
    22441 ctgccgcgct ccggcggcgg caccgtcgag accgccagcg tctaccagcc caccacgccc
    22501 gacagcgcgg gcgtcggcgg tgactgggtg aacagcttcc ccctgcccga cggacggacc
    22561 gcgctggtgg tcggcgacgt cgtcggccac ggcctgggag ccgcggcgac gatgggccag
    22621 ttgagcatgg aggcccgggc gctgctgtcg gcggggctcg cgcccgacga ggtgctggag
    22681 cacctggacg agaccgtgac gctgctggac gacacggact ccggcctggc ggccggctac
    22741 agcgccctcg ggtcgacctg ctgcatcgcc gtctacgacc cggtcggcca ccggctggcg
    22801 ctgtccaacg cgggccacct ccccccgatc ctggtgtcgc cggacggacg ggccggcgcc
    22861 ctcccggtcc acccgcaccc cggactgggc gccgagttcg ccctgcggga gccgttcggc
    22921 gtgcacacct tcgccgctcc cccgggctcc ctgctcgccc tctacaccga cggtctggtc
    22981 gaggacccgg ccctgccgat cgacgagggc atcggcaggc tgacggaggc cgtggccgcg
    23041 gtgcacccct gggacgcact gcagcaggcc gcgcggaagg tggtctccga ggtgatgccg
    23101 gcccaccggc gcgacgacgt gacgctgctg ctcgcgcgca cgatcggcca ccgcaagggc
    23161 gacaccgcca cctggcgcct gccggcccgc gaggacgcgg ccgcgcgggc ccgcgcgctg
    23221 gtctccgcgc tgctgcggca gtgggacacc agggacgcca cccgggacaa ggtgctgctc
    23281 ctggtcagcg agctggtcac caacgcggtc cgccacgccg gcggacccat caccgtacgg
    23341 ctgatccggg ccgggcacgg cctgctgtgc gaggtcggcg acaccggcaa cggcaggccg
    23401 cggctgggcc ggggccggac cctcgacgac aggggccgcg gcctgcacgt ggtgcaccgg
    23461 ctcaccaccc ggtggggggt gcgctggacc gagtccggca aggtggtctg ggcggaggtc
    23521 gcccgctgag gccgccgcgg gggcgcacgc cgggagcggg aaccggaacc ggggcgcgga
    23581 gggcctgcgt cggtcgaagc acgagatcac ccgcgcgccc cgaggagtcc gagatgaccg
    23641 gcacggccac ccgttacctc tgtctcgccc ggcacggcga ggcgtccccg gaggggaccg
    23701 aactgacggc ggcgggacga cgccaggcca cgctgctggg caggcggctg cggggcatcc
    23761 ccttcgccgc cttccaccac ggcccgctgc cgcgggcgcg gcagaccgcg cgcctggtcg
    23821 ccggcgagct gaccggtgtc actccgtgcg tctcggaggc cgcgggtgac tacctgcccc
    23881 acgtaccgga acgggccgag ctcccgcccg agtcggcgga ccactgcctc cgcttcctcg
    23941 ccggtgtcac ggacgaggag cgggaacgcg gagcggaact cgcccggcag gcgctgcgcc
    24001 ggttcaccgg gccggtgacg gacggccccg aggaccggca cgaactggtc gtcacccaca
    24061 acttcctcgt cggctggctc gtccgtgacg ccctgtacgc cccgaagtgg cggtggctcg
    24121 gcctcaacca cggcaacgcg gcgctcacgg tcatccgcta cgcccccggc cgggcggcct
    24181 ccgtcctcgt ctccaacgac atgcggcacc tgcctcccga gctgcgctgg acgggttttc
    24241 cccgcgagga gcacgtctga gcgcgggtgt cgccacggcg tccggcgtcg ccttcggcat
    24301 gccggacggg tgctcaggag ccgtgaccgc gcaggacggc cgcgaggaag ccgacggcgg
    24361 ccgggtcgcg ggagctctcg acgaggtcga cggagtcgag ggtgacgatc cagtcgttcc
    24421 ggccgttccg gccgttccgg acggcggaga cgtcggcgag cggctcggag gacttgagga
    24481 agcggcgctt gtgccccgcg gtggtgtcgc cgacgtcgcg gctcgctcgt ccgcggcgtg
    24541 caggcgtgca ccggcggccc cgggcggggg ccttcactcc tcgcgcgggg cgcagaggcc
    24601 ggccagggtg cgggcgacgt cgagcacggt gctgtgcggg agccacaccg ggaggcggac
    24661 gtagcggtcg tggctgtgat gcggggagaa cgccgggccc ggggtgagcc gcaggccgcg
    24721 ctccagggcc cggccggaca gccgcacggc gttgccgccg gtgtcgatcc acaggccgga
    24781 gccgccggcc gggggctgcc accgccagtg cggaagcgtc gcgcggagca cctcctccgt
    24841 gtccgcggcg tgccgcagca ggaacgcgcg ccggtgctcc cgctgctccg cggcacgggg
    24901 cagcaggagg agggcggcga gctggtcggc gacggggctg ccgaggtcca ccgcccggcg
    24961 cacctccacc agccgcccga ccaactcgcg gggaccgcgg acccagccga cgcggatgcc
    25021 gccccagaac agcttggaga gggtgccgac ggtcagcagt ccggcggggt cggtgtgctg
    25081 gtccaggccc ggcagcggct gggaccggtg ccagcccagg tcggcctggg actggtcgtc
    25141 caccaccagc agtccgtggc gcgcggcgag ttcgcccagg gcccggcgcc gcggaccggg
    25201 cgtgtggacg cccgtcggat tgtgcagcgc ggtctggacg tagagcaggt ccgccccggc
    25261 gccggcgcgc gcgagcaggt cgaggtccag gccggcggag gtgaaccgta cgccctggac
    25321 ccggccgccc gcgccggcga acgcctccag cgcaccgcgg tagctcgggt cctccaccag
    25381 cgtgagcgtg ccgggcccgg tgagcgccgt ggcgatcagc cagaccgcct gctgcgatcc
    25441 ggcggtgatc actacctcgt cctcgcgggt cggcaccccc cggcgggtga agtcggccgc
    25501 cagcgcctgc cgcagctcgg ggaggccggc ggggtggtag ccgggtccgc gcaggtggtc
    25561 ccggagcagc cggccgacct ccggcatgac gtcggcgacc aggtcggatc cggggagcgc
    25621 gccggaggac aggtccacca ccggccgtgc gccgtcgaag gaggtcagcc gcccctcccc
    25681 cggccgtgcg gcaccgcgcg caccgcgtac gtaggtgccc gagccgtggc gcggggcgag
    25741 gcggccgtcg gcgacgaggt ccgcgtacgc ccgcgcgacg gtgccccggg cgacgccgag
    25801 cgcctccgcg aggtcccgct gtcccggcat gcgccacccc ggtggcaggt gcgcgccgtc
    25861 gaccagctcg gccagggcgt cccgcagggc cgttcgcacg ggctggtccg tgcgccacgc
    25921 gccgagcagg cgtgccaccc gttccgcctc gccgcgcatg cgcccgctcc tctcccgacc
    25981 ggcgtggacc acttgcctcc aagtggacca cgccgccgac cggcggagcc cgaggatggg
    26041 tacgtcggct cgaaggagag cgggaggtag ggacatggcg acggtggtgc tcctcggcac
    26101 cttggacacc aagggtgccg agtacgcgtg gctcgcggag cggctgcgcg gtcacggggt
    26161 ggacgtggtg acggtggacg tcggtccgct gtcggacgcc gccgcggacg tcaccgcggc
    26221 ggaggtggcg cgggcggcgg gcgccgacct ggcggcgctg cgggccgcgg gcgaccgcgg
    26281 gagggcgatg gaggcgatgg cggcgggcgc cgcccggacc gtcaccggcc tgcacgcggc
    26341 cgggcgcctc gacggcgtgc tggcggtggg cggctcgggc ggcacgtcgg tggcgtcccg
    26401 ggcggtgcag gagctgccgg tgggcgtgcc gaagctgctg gtgtccacga tggccgcggg
    26461 cgatgtcacc ccgtacgtgg gcgcggtgga cgtcacgctc atgtacgcgg tggtggacgt
    26521 ggccgggatc aactcgctgt ccgagcaggt cttcggcaac gcggcggcgg gcgtctccgc
    26581 catggcgcgg gagtacgcgc ggcggcgtgc ggcccccgcc accgggcacc gcccgctggt
    26641 ggggctgtcg atgttcggcc tgaccacccc ggcggtcgac gaggccaggg aggagctgga
    26701 ccggctgggc tacgagccgc tggtcttcca cgccaccggg gccggcggcc gcaccctgga
    26761 gaagctggcc ggtgacggcc gcttcgcggg cgtgctggac ctgacgacga cggagctggc
    26821 cgacgacctg gtcggcggcg tgctcagcgc cgggcccggc cgtctggagg cggccggcgc
    26881 gcgcggagtc ccccaggtcg tgtcgcccgg cgcgctggac atggtcaatt tcgggccgcg
    26941 cgcgaccgtc ccggcccggt tcgacgaccg cacgttcgtg gtccacaacc cgacggtgac
    27001 cctgatgcgt acgacgcccg cggagaacgc cgagctggga cggcgcatcg gcgccaagct
    27061 cgccgcggcg cggggaccgg tcacggtgtt cctcccgctg cgcggcgtga gcggcgtcga
    27121 ccgggacggg ggcccgttcc gggacgcgga ggcggacgcg gcgctgttcg ccgcgctgcg
    27181 cgaggcgctg gccgggtcgg ccgtggaggt cgtggaggac gacgcgcaca tcaacgaccc
    27241 ggggttcggc cggcgggccg cgcaccgcct gcacgagttg atcaccgccg gacggtgacc
    27301 cggggcccgg cccgacccgg cgccgggcag gcagcgaacg gcccacgcac cgtgggcacg
    27361 aggaaggagc gacatcatgg accgcgcaac ggccctgcgg cggctgaggg agacggtggc
    27421 gtccggccgc ccggtcatcg gcggtggcgc cggcaccggc atctccgcca agtccgcgga
    27481 ggcgggcggc atcgatctgc tgatcatcta caactccggg cgctaccgca tggccggccg
    27541 gggttcgctg gcgggcctgc tggcgtacgg cgacgcgaac gcgatcgtga tggagatggc
    27601 cgacgaggtg ctcccggtgg tgcgggacac ccccgtgctc gccggggtca acggcaccga
    27661 tccgttccgg gtgatgggcc ggttcctgga ccggctgaag gaggccggct tcacgggcgt
    27721 gcagaacttc ccgacggtgg ggctgatcga cggcgtcttc cggcagaacc tggaggagac
    27781 cggcatgggc ttcggccacg aggtcgagat gatcgccgcc gcacacgagc gggacctgct
    27841 gacggctccg tacgtcttcg acccggacca ggccgcggcg atggcggagg ccggcgccga
    27901 cgtcctggtg ccccacctgg ggctgaccac caaggggacg atcggggcca ccaccgcgct
    27961 cggtctcgac gagtgcgtcg accggatcca ggcgatgcgc gacgcggccg tgcaggtgaa
    28021 tcccgacatc atggtcctgt gccacggcgg gccgatcgcc gagcccgggg acgcccagta
    28081 cgtgctgtcg cgcacgcgcg gcgtggtcgg cttcttcggc gccagctcga tcgagcggct
    28141 gcccacggag acgggcatcc gccggcagac cgaggccttc aagtcgctgg ccctgccggc
    28201 cgcggagagc ggcggccccg gctccggcac ctccccgcgc ggctgacccc ggtcgccgcc
    28261 ggtacgcctc gccaccctcg ccccgcctca gcggtcatcg tcccggcgtg gacacgcttt
    28321 ccggctcggt actccctccg cgtcgcggga cgcggaccag gacgaggagg tcagcgatgt
    28381 ccacggccgc gcccgcccac acgcgcaccg tggtcgaagg gtcgctgcgc atgaacctgc
    28441 gtgaaagcgg gcgggccgcc gccgacatga tcgccgagcg gctcgcctcg ccgcaggaca
    28501 tacgggggcg gcatcaccgt cagggctggt ggccgcagtc gtgccacggc gcggccggtg
    28561 tcgcgctgct gcacatcgag cgggcccaca ccggccaggg gccgtggcag cgcgcccacg
    28621 actggctcgc ctgcgccgct gccggttggg ggcgtagggg aaggcgaccg cgaggtcggg
    28681 ccacaagccg tcccggtact ggcaggccaa caggaagcgc tagaagccgg agctcagctc
    28741 cgcgatgacc ttcccatgcg gcggggtcgc agcaccgccc gcccggcgcg ctcctgggcc
    28801 tggacgatgt ctccgcgggc cttgccactg aggcagacct gcctgccgac gtaccactcg
    28861 gtggcacgac ggcggcgccg ctggcgggca acgagccaac ggtccgctac gaggcgaccg
    28921 tgctcgtcgc tgccctcaac gagtggatgt gatcaacacc gccacagatg tcctacgcga
    28981 ccctgaccac gtacttgccc tggacgccgc ccgcctccag cgcatggtgt gccgctgctg
    29041 tctcctccag ggggaagact gtgtccaccg cagggctcag cttgccctgg gccacatggc
    29101 gggcgaggtc gtcgaagtcc gcccgcgtgg ggttgccgct gaagaagcgc acccggccgt
    29161 gtccgtggac cgtgctggcc gcgaggtagc cgagcgacgc agcgggccgt ttcaggtcga
    29221 aggcgatggt gaccatgcgc ccgccgggat tcagcaggcg ccggaaggcc cgcaggtcgg
    29281 tccccgcggt gtccacgacc acgtcgaacc ggcccaactc cgccggccgc acgctccggt
    29341 ggtcgacggc cttgtgcgcg ccgagcccgc ggacgaagtc gaggttggct gcgcgggcca
    29401 gggccgtgac ctctgcgccg tacgcccgtc cgagctggac ggcggcgttg ccgacaccgc
    29461 ccgccgcgcc ccggacgagg agtcgttcgc cggggcgcag cccggctttg tcccgcagcg
    29521 cggtgatggc cgtggtggcc accggcagtg cggcggcgtc caccaggtca aggccgtcgg
    29581 ggacccggcc gacccgctcg gtgggtacgg tcacgtactc ggcggcgctg ccgaacccgg
    29641 aggtgcggcc caagaccccc cacacgcggt cgccggccgc gcaccgcgtg acgccggccc
    29701 ccagcgcggc gacctcgccg gtgaagtcca agccgacgcg cttggggaat ttccggccgg
    29761 tcaggaggcg gaggcggccg gcacgggctg ccagttcgcc gccgttgacg ctgaacgcgc
    29821 gcaccttcac caggatctcc ccgggggccg gctcggggcg gggcacgcgg cccgtgtaga
    29881 gcacgtcggg gccgccgtag cggtcgtaga gcactgcctt catcatgcgg tcgtccatgg
    29941 ttctgccttt gccgccgggg gccgtacagg gatctggcat cgaccgtaag ctctcaagtg
    30001 gacgcaatcg tccgcttgga ccggaagtga gagacagtga tgacggaagc ctctcggatc
    30061 acagcccggg acgggatgcg ggcggatgcc cggcgcaacc gggagcgggt cctcgtcgcc
    30121 gcccgtgcgg tcttcgcgga gcacgggatc gacgccccga tggcgaccgt ggcccgacgg
    30181 gccggggtcg gcgtggcgac gctgtaccgg cacttcccga cccgggacgc cttggtgagg
    30241 ggcgcgttcg cgcagcagat ggagacctgc gcgcgggcgc tcaccgaggc tctggccgac
    30301 cctgacccgt ggcaaggctt ccagcagctg gtcgagacga tctgcgctct gcaacgggag
    30361 gaacgcgggt tcccggccgc gttcgccgcg gccttcccgg acagcacgtc ggaacacgcg
    30421 ccgtaccggc aacgagccga gcgggacttc acgactctgg tgcgcagggc ccaggcgtcg
    30481 ggcgcgctgc gggccgattt tcacccttcc gacctcgccg tggccctgtt ggcgcactgc
    30541 ggtctggtga ccgctctgcc ggacgacggt gcagcgtccc ggcgcctggt ggcctatctg
    30601 ctccagtcgt tccgcaccga cccggccaac aaaccgctgc ccccgccgac tgcgctgaca
    30661 ctgcgcagct tcccgattgc aacggacagt ccccagggtc agcggtcctc cagagcctga
    30721 catgaaacgg tacctgccgc agggcacgtc cagtccgaca gctccgcttt cgcgacagga
    30781 cccagccggg ccgaagaatg tgagagggct ggacctcaca tcggacggag ctgtctcgtc
    30841 gtaggggcat gaacacgaaa ctgcgctacg ggtgtctcgg cctgctggtc gtgactgccc
    30901 tgtatacggg cgcgtgggcc tacttcgcac cggagtcgtg gcacgagaac ttccccgggt
    30961 tcggattgag ctggctcccg cggctgggcc cgtacaacga gcacctcgcc aaggacaccg
    31021 gagcgatgtt cctggccctg gccgcgctga cgctgatcgc tctgcgggac gtacgcgaca
    31081 accggctggt ccggatcacg ggcgcggtgt ggctggtgtt caacgtgctc cacttcagct
    31141 atcacgtcca acatctcggc atgtacggga cgcgcgacca ggtgctcaac gtcctgtccc
    31201 tgtccgcgct ggtgctcgtc tccgttctgc tcctggtgcc gctcggcccc gtacgacgga
    31261 acggcacacg gtgacgtacg agaacacgac ggaggcgagg atcggcgtgc ggatcgcggt
    31321 ggctggaggg accgggctgg tcggacggct cgtggtcgag gaggtgaccg cggccggaca
    31381 cgagccggtg gtactcgccc gctcacgagg ggtggacctg acgacggggg cggggctcga
    31441 cgccgccttg cggggcgccg aggcggtcat cgacgtgagc aacctgacca cgacgagcgc
    31501 caagaagtcg tgcgcgttct tcgagcgggt cagccgtgaa ctcctggacg ccggagcgcg
    31561 ggccggggtg ggacaccacg tcgccttgtc gatcgtcggg atcgaccggg tcggcatggg
    31621 ttactaccag ggcaagctgc gccaggagga cgtggtgcgc aacggcgcga cgccgtggac
    31681 cgtcttgcgc gccacccagt tccacgagtt cgcgcagcag acgctcgacc gggtgccgag
    31741 acccctcgcg gtggtgccca ggatgcggac gcagccggtc gccgcccgcg aggtggctca
    31801 gcacctggtc cgcctcgccc tcgcccccgc gcaaggtatg gcccccgatc tcgccgggcc
    31861 ggccgtcgag cagctcgtcg acctgacgcg ccgcctgcta cgggcccgga acgagcggag
    31921 attgctgctg ccggtcacct tccccggcgc cgcgggccgg gccatgaagg gtgacggact
    31981 gctgccgacc ggccggggac cgcgcggcag ccagaccttc gacgcctggc tcgcccacca
    32041 cgtggccgac accgccccgg ccgccggaag ggggtgacga gcggatgccc acgccctccg
    32101 acgccgaatc cggatccgac tccgccctca ccctccactc tctcctggcc gagcgccgcc
    32161 acctgctcaa tctcggctac cggatgctcg gatccgtgca ggaggccgag gatgtcgtcc
    32221 aggagacgta cgcgcgctgg tacgccctct ccgaggaggg ccgggaggcg atcgcggccc
    32281 cggaggcgtg gctgacccgg gtcgcctcgc gcatctgcct cgatcacctc gcttccgcgc
    32341 ggatgcggcg ggagcgctac accggtgaat ggctgcccga acccgtccgg cacagcgcca
    32401 cgtggagcag caccgacgcc gcgcacgcgg gcgaccccgc cgaccggatc accctcgacg
    32461 aatccgtcag catgggcatg ctcgtggtcc tggagacgat cacgcccgcg gaacgcgtcg
    32521 ccttcgtcct gcacgacgtc ttcggcgtgc cgttcacgga gatcgccgag acggtgggcc
    32581 gcacccccgc ggcctgccgc caactcgcct cctccgcccg caggcgcctc gcccgcgaac
    32641 ggaccggcgg cagcacgacg ccggagcacc ggcgggtcgt ctccgccttc cgcgaggcat
    32701 gcgagaccgg tgacctcggc gctctggtcg atctgctcga ccccggcgtc aagtcgcgca
    32761 gcgacggcgg cggcaaggtg cgggcggcgc tgcgtcccgt actcggccag gacaaggtgg
    32821 cccgcctcgt cctcggcctc ctgcgccagg aaccggaggt ggaactcgtc gaggacgatg
    32881 tcaacggcgc cccgggcctg tccgtccgca tcgccggcac cacggtcgcc gtcctgtcca
    32941 tgggcatccg cgacggtctg atcgccgacc tgtggctggt ggtcaacccg gacaagctgc
    33001 gtgcgtggac gaggtacggc acggaatgag gcggcgttcc gatcaccggg tgggagtcag
    33061 gtgagcccgg ccgtggcgtt gtcctcccag ccgtcgaccc gctgtcgggg accatgccgc
    33121 cggtgacgtt cccgtgccgg tcgacgccga cgaacgcggg cgcgccggcc tccgcgccgc
    33181 tcccccgcct tcagcagttc cacggccgcc gcctccagcg tcgcccgcgc ctgcgcctgg
    33241 tcgtcccggc ccacctgcgc accgcggcgg cgcagttcgg ctacggcccc ggcgaggatc
    33301 gtgctcgccg acgaggcggc gtagccctcc cgtccactcg gccccggtcc agcagccaga
    33361 cgacgaacgc caccaacgcg ccgcgcgtgg cctccggttc ggggaacccc agcgccgcgc
    33421 agaaccgcgt cccaaccttc cacgccttcg cgtacgtgtc cgtcgtgttg gccggtcgca
    33481 gtcgccgctg cacctggtcc gcgaagtccc ccgcgtccgc cgggcgctgc gcgacctcca
    33541 cgccgtggcg ctgcgcccac tgaacgacca gaggtgaccg ctccgccggc tgggtgcagg
    33601 ccctcgctgg tgccgatgac gacgaagcct ggcggctcag cgagcgaaat ctcggttgcc
    33661 tatgggcgcg ggagttggat ccaatgaccg gcatgatcac ccgggcgcgc ctgcctcggc
    33721 gggacgtgat gatcgcgcac cgtcagcggc cggcgcgcga tccgggcgga ccgcgaccgc
    33781 atcgtcccag gggagacgcc acccgatgaa cacgccacca tcgccgtccg gagcggagca
    33841 cacagacggg tcgtccatcc gcctgggtgc tctcgtcccg ctgacgcggc ccggctgggt
    33901 cgaggcgggc cgacacctgc tcgcaggact cgacctggcc gttcgcgagg tcaacgacgc
    33961 cggcgggatc gacggcagac cactggagtt ggtggtccgg gacaccgcgg ccgatccgga
    34021 gcgggctgcg gcggccgtgg acgaactggc ccacctgggc gtgaccgccg tggtgggtga
    34081 gtatcacagc gtggtcgccc gcgccgccgc tgcccgagcc gacgcgctcg gcgtgccgtt
    34141 tctctgctcc tccgcggtgc tcgacacgct caccgaggaa ccgacggagt gggtcgcgcg
    34201 tctggccccg gcccagtcct acgggtggcg gatctacgcg gacttcctcc tccgctcggg
    34261 ccggcgtcgg atcgccgtgg tgacccagcc gagcgtctac tgggcgtccg ggacccgcgt
    34321 cctgcgggac cacctcgctc cccgcggcgg caccgtcctc gaactcgacg cgacgctcac
    34381 gcccgaggcc ctgtgcgacg cgctcgtcga cgatggcgcg acggcgctcc tcctgctggt
    34441 cggccatccg gagccggcgg tgccgatcgt ccgggccgtc cggggcgacc ggcggctcgc
    34501 ggagatcctt gtcggcgctc cggccggaca accggagttc gcggaatggg ccgcggcgct
    34561 gggcgaggac ggcgccgggg tcccgttcct gcgctacctg cccgagcgcc tcggtccgct
    34621 cggtgaacgc gtcgggaagg aactccgcga gcggcttggc gaagcgccct ccttcgtcgc
    34681 cttcgagggc tgggacaccg tcgccgtcct cgctgcggtg ctgcgttccc acggcacgga
    34741 ccgggcggcc atcgccgagt catggccgcg cgtggcggtc gagggcaccc gcaggccgat
    34801 ccggttctcc cgcacgccgg gcatcagcgt ctggcaatgg gcctggacac cagtccaagt
    34861 cgttgaccgg gacccggcgg aacccgaccg cttccggatc ctccacgtcg gctgagtgag
    34921 catggaagtc caactgcccc gctctgccga acttcgaaag tgctggtcac agccactcgt
    34981 tgacggcggc gacgaggacg gtcacctcgt agcggacagc aagcttgtcg tacctcgtgg
    35041 cgctggagcg gccggtggtg cgggtccgtc gggtggcgcc ggggctcggt ggggttggcg
    35101 ggtcacgcgg tcagcgcgag ggccagagcg tgtcgcacgc cgcggaggca tgctggttga
    35161 accctccccg ccgatcatgt gatgtgcccc ccgggagggt gagtcaacag tcaaaccccg
    35221 tacagaggga gacagtgccc gatacgaaga tcgcttgtcc gtgatcttcg agaggaatcc
    35281 ccctcgtgtg tctcccccgc gccgttggcg acgcgctcac cgctttggtc aatccggttg
    35341 ccgctcattc cgcccccgga aacacgaccg ctttctccgc ttccgcgtgg ggacttgtgt
    35401 acggcgcggg ggaacttctg tgacctccag gtcggcgtgt gacgaccgtg atgccagcgg
    35461 gccacgggac ggctgtgcac cgagtcacga gggaacgggg ccgggcggac cgggggtggg
    35521 cgtgggtgtg gacgggggcg gatggctgtc cttgctggcc tgtcacagtg tcaggaatcc
    35581 cgcgcgcacg gtgtgggcgg cggtgctctg cactgcggct gtggtgtgcg tggcgatgct
    35641 tggcaccacg gcttcttcct tgtcgccggg gggatacaac tccgtgggta cggagtccgc
    35701 gcacgctgat ggactgttgc ggaagttcag gggggatgac ccggggctgg tgctacgggt
    35761 caggtcggag gactcggtcg attcggcacg ggcgcgttcg gacggggcgg cgctggcgcg
    35821 gcgggttgct gctcaaccgg gagtggccgc ggtggaggcg tactggacgt cgcgttcgcc
    35881 cgccctgcgg gcgaacgatg ggcggtcggc gctcatcggt gtcgcgctgg agggtgatga
    35941 ggcggcgcag gcgcgtgccg cgtcgcggct cgtgccccgg gtgacgggtc ggcagggcgc
    36001 gctgcgggtg tcggccgggg gtcgggtctg ggccgggatc caggcggcgg agcagggcga
    36061 aagggacctt gtccgggcgg aactggtggt ggctccggtg gtcttcgggt gcttggtctt
    36121 cgctttcggc tccctgctgg cggcactgtt tcccctcctg gtgggagcgt tggcggtggc
    36181 gggatcgtgg gcgttcttgc gcctgctggg tggtgtgacg gaggtgtcgg ccatctcgct
    36241 gaatatcgcg gccaccttgg gcttcgggct ggccgtggac tacgccctgc tggtcgtgac
    36301 gcgctttcgt gaggagggcg cgcgagggct ggcagtgccg gatgccgcgg tcagggcggc
    36361 ccggaccgcg ggtcgcagcg tgcttgtctc tgccggcgtg gtggcactgg cgttctcggc
    36421 gctgtgggtg ttcccgttcc cgtggctgcg gtcgatggcc gtggccggga tcgcggtggt
    36481 actgctggcc gcgacggcga ccgtcgtcct ggtgccggcg ctgctggcga tgctgggctc
    36541 ccggatcagg catcgccggg cggcgtcgag tccggcctgg cggcggctcg tccggtgggt
    36601 gaccgggtca ccgtggctgt ggggggcctg ttgcgcggtg ctgatggccg cgctggtgtg
    36661 gccgttcggc caggcccagt gggggttcac cgacgaacgt gcgctccccg ccggctcaca
    36721 ggcccggcag ttcaccgaac gcctccgcac cgatttccct gctcagcccg accgcgatct
    36781 catcgtcgta ctgaccccgg tccccggcga ccgcgaggtc gaccagtacg cgcgacgtat
    36841 cagtgcgctg ccgggcgtcg tccaggtcac cgctccgacg ggccgctacc acgaccgccg
    36901 tcgcaccgcc gtcgtcgagg cggtgtcgga cagtgcgacg gcggtgtggc tgaaggcgtc
    36961 tacggggctg gatccgcagt cggcgcaggc cgcacgcctg gtggagcggg tgcgggagct
    37021 tcccccgccc ggaccgcgct gggtgggggg ttcgcccgcc cgtcatgttg atgcgaaggc
    37081 ggctctggcc ggtcgtgtgc cctgggccgt gctgctgatg tcggccacga cactcactgc
    37141 gctgctgctc tacacccggt cggtgctgat tccgctgaag gccgtcgccc tggcggcgct
    37201 gagcctgacg gccagcctgg gcagcatggt ctacatcttc caggagggcc atctgcgctg
    37261 gctggtcggc gacttcacga ccacgggctt cttggacatg acgattccgc cgctgctgtg
    37321 tgcgatcgcg ttcgcgctgt cgttggacta cgaggtgttt ctgctggccc gggtcaagga
    37381 gcactacgac gccggcgggg atcaccggga cgcgatcgtc gagggcgtcg cccgcacggg
    37441 ccggctcatc accgtggccg ccgtggtctt cgccgtcagc atggccggac tggcgagttc
    37501 cggcatcacg acactgaaga tgatgggcgt gggactcggg gtggcggtcc tggtcgatgc
    37561 cacgctggtg cgcggcatcc tggtgccggc cttcatgcag ctgaccgggc gagccaactg
    37621 gtgggccccg gcatgggtca gacgacccgc cacgcaggaa gcgcatgccc cgcagcacgg
    37681 gcgggacaca gtggctgaga gttccgcgga ggcgcccgcg gctcactgaa ctccgcggtg
    37741 cggcggtcag ttgctctcgc ggcgggtgag ccgcctggtg aggaagacgg ccagtgcggc
    37801 ggtggccatt cccgcggcag cgtcgaggac atagtggtaa cggcagtaca ccacggacac
    37861 ggtgatcagc gcggtggccg cgatcatcag ccgtttcgcg gggcgcggta cggaggcgcc
    37921 ccggatcgag agcgccgctg cccaggcgcc ggcgacgtgg gaggagggga agcaggtgcc
    37981 gggcgggtcg gcgctcgcca tcagttgcgc ctggaggggc tgggcgaggt agccgtgcaa
    38041 gtggtcgggg gtgaacgccg gggcgagcgc ggcgacaggg ccggcgaggg gcagcagcat
    38101 gaagccgagg aagcacaggt agtgggcgag gcacaggccg aggacgtagc ggtgcagggc
    38161 ctggtgcatg cctttggcga ggaagtaggc cgggggcagc acgaagtaca ggtagtagga
    38221 gctgtagctg aggctgaggg cctcggtgag agggcgggag gcgagagcgc cgagcaggag
    38281 gttggggtgg gcgccgaaca ggtgctgttc ccagaccagc atggtgtcgt cgagcaggcg
    38341 gccgtgcaga gcgagcgact gagggccgga cgcggagaac agcagcggag cgcaggccag
    38401 cgggtacagc gcgcgcacgt tcgccagggc cggcgatgcc cagtggcggt gtgccgcggc
    38461 gcaggcgagg acgaacccgg ccagggccgc gtaggccccc gtcagccacg cggcatgcgg
    38521 tacggcctcc tggcccagga ccaccgccgt ggcagccacg aagagatacc cgagggtcac
    38581 cttctccaca gccctcagaa gcggcctgcc tgccaggtgg tgggggtggg gtcggcggac
    38641 gacaagcgat gtggtccgaa cgggtgatag ctgtgcgggg agagagggcc cttgccgcac
    38701 cgcgcgggca ggtgccggcg catggtgagg ccctcggcgc cggcagggtt tccgctgatc
    38761 agatgtggtc aagggacctc gtgcatcctt gcgttgggtg tcaggtgtcc gtacaggaga
    38821 cacccaccat tacagcttgt caccgcgtga ctccaatggg ctaaggttgc cgcgatcttg
    38881 gagcgcaccg tgacagggca ggtaagcgat gtcagatgtg agtggaccgg ccgccacctt
    38941 ggccgccctc gacagggccc ggcaaacagg tggctatccg tgtttccgcc ggatcacggg
    39001 gcagccgggt ccgggagaag tcttcgtcga gggcttgcgt gcgatcaacg cggcctccgg
    39061 tgactacctc ggcctggcgg cggatccacg ggtgcgcgag gcggcggcgg ctgcggcgcg
    39121 cgagctgggc gcctcctgct ccgggtcccc cgcggtgatc ggcacctggt cggtgcacgc
    39181 gcaactggcc gaggaactcg cggacttcct gcaccggccg gcggtgctgc tgtccaccac
    39241 gggataccag gcaaatctca ccctggcctg cctcttcggc gaggaccgtg cagtcgtcgc
    39301 cgaccggcac atccatgcct ctctcgtcga tgcgttgcgg ctcggccccg ccaagtaccg
    39361 ccggttccgc cacaacgcgc ctgaccacct ggcgcggctg ctggaggagg cttcgggaca
    39421 gggcctgtcg ccagtggtcc tgaccgaggg ggcgttctcg ctgggcgggg aactggctgt
    39481 actgcccgag atcgccgatc tcgccggacg tcatgggggg atgctcatcg tcgacggggc
    39541 tcacgacatc ggcatcctgg gaccgtcggg gcgcggagcc ggtgagcacc tcggctgcga
    39601 gcaggacatc gacgtactgt ccgggacctt ctccaaggcg ttcggggccg gtggcggata
    39661 cctcgccgga agcaccgaac tcatcgagca ctgccgcttg ctcgggaggg ccaccatgta
    39721 ctcggcgtcc atgccaccac cgaccgccgc ggcggcactc agggcgctgc gcatcatcag
    39781 ggacgagccc gaacagcgag ccgtcctggc acgcctggcg ggccgtctgc acgacggact
    39841 ggccgaggtg gggtacgacc gtcccaactg ggccagcccg gtcgtcacgc tcccggccgg
    39901 cgacgccgac cagtgcctgc gcacgtggcg ggcgatgctg gaggccggtg tgttcgcggc
    39961 gccgttcctg ccgccggccg ccccggcggg acagtccctg ctgcgcctgt ccgtcaccgc
    40021 ggcccacacc gaggcacaca tcgaccacat cctggaggtc gtgggccgac tcgtgccgac
    40081 cgtcgacacc actggcgtgg cggcggcgcc gatcccgtgt cccgcctgat gcgcgctccg
    40141 cggcccccgc aaggcgctgc cgacatcgtg atggtccgca gccgcgccga gatggatgac
    40201 ttcatcaggc tgccctacca gctgtaccgg gcgcacccgc actgggtcgc cccgctggaa
    40261 gtggaacggc ggcagttcct caacccgcgt cgcaacccct acctgcgcga gagcgacgtg
    40321 agctacttcc tggcgcgccg cggacgggcg cctgtgggcc gggtcgcggc catcatcggc
    40381 ccggacggac cagcccgcca acgccaaggt tacgtgggct tcttcgagtg caccgaagac
    40441 cctgccgtgg cgcgcgccct gtgggagcag gcgatggcct ggctgcggga gcgggacgtg
    40501 cagaccgtga tgggcccgat gaacccgaac atgcaccacg agtgcggcct gctcgtcgac
    40561 ggcttcgacg acgccccccg catcggcatg ccctacaacc ctccctacta cccggacctg
    40621 ttcgccgcga gcggcttcac tccggtcaag gaactgctgt cgtggcggct gtcaccgacc
    40681 gaccccaggc tcaagcggtg ggccggctac cgcgacatgc cgcggcgcaa gggcggcctg
    40741 acggtacgag cagcaaactg gcgccgcttc agcagcgagt ccgatctcgt acgggagctg
    40801 tatcacgcgt gctggcagga caactggggc ttcgcgccgg cgaccgacgc ggagttcacc
    40861 tacctggcac ggcagatccg gctgctcgcc cccaccggcg tccgcatcgt cgagcacgcg
    40921 ggaacccccg tcggcttcag catcctgctg cccgatttca accaggccct ggcgcccgct
    40981 cggggacgcc tgacccgcta cggctggccg gtcggagcct ggcgcgtgtg gcagggccgg
    41041 cacgccatca cccggggccg cgtgatggcc ctgggagtcc gcgaagacag ccgcgcccaa
    41101 ggagccacgc tcgccctggt caccgatgca gtcgccggcg ccctgtctcg gggctggaac
    41161 gagctcgacg tgtcctgggt cctgg
//
