LOCUS       NZ_CFVJ01000033        16543 bp    DNA     linear   CON 04-AUG-2024
DEFINITION  Streptococcus pneumoniae strain 17F/2, whole genome shotgun
            sequence.
ACCESSION   NZ_CFVJ01000033
VERSION     NZ_CFVJ01000033.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1
  AUTHORS   Informatics,Pathogen.
  TITLE     Direct Submission
  JOURNAL   Submitted (10-MAR-2015) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001326475.1-RS_2024_08_04
            Annotation Date                   :: 08/04/2024 01:25:18
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,120
            CDSs (total)                      :: 2,087
            Genes (coding)                    :: 1,951
            CDSs (with protein)               :: 1,951
            Genes (RNA)                       :: 33
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 27
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 136
            CDSs (without protein)            :: 136
            Pseudo Genes (ambiguous residues) :: 0 of 136
            Pseudo Genes (frameshifted)       :: 59 of 136
            Pseudo Genes (incomplete)         :: 74 of 136
            Pseudo Genes (internal stop)      :: 39 of 136
            Pseudo Genes (multiple problems)  :: 30 of 136
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 23:58:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 16543
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CFVJ01000033.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..16543
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..16543
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..16543
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="True"
                     /core_location="[5667:6543](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5668..6543)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            complement(130..1953)
                     /gene="lepA"
                     /locus_tag="AP598_RS09440"
                     /old_locus_tag="ERS012477_01845"
     CDS             complement(130..1953)
                     /EC_number="3.6.5.n1"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="lepA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /locus_tag="AP598_RS09440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01845"
                     /product="translation elongation factor 4"
                     /protein_id="WP_001047222.1"
                     /transl_table=11
                     /translation="MNLEELKKRQRKIRNFSIIAHIDHGKSTLADRILEKTETVSSREM
                     QAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAAC
                     EGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVIGLD
                     ASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQVRVM
                     DGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQDTRVGD
                     TVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETS
                     QALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMDVSNPSEF
                     PDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLA
                     EIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFIVHKDFAYER
                     GKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGGDVSRKRKLLE
                     KQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(2032..2760)
                     /locus_tag="AP598_RS09445"
                     /old_locus_tag="ERS012477_01846"
     CDS             complement(2032..2760)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /locus_tag="AP598_RS09445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01846"
                     /product="metallophosphoesterase family protein"
                     /protein_id="WP_000133332.1"
                     /transl_table=11
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQPQLLFLGDLIDRGEDSHR
                     VLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLDAP
                     VDGVEDAKRVAAEASDLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKVWLR
                     KPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLHGIVF
                     TDQGMTEHHFIENDGFVAED"
     gene            complement(2762..4429)
                     /gene="recN"
                     /locus_tag="AP598_RS09450"
                     /old_locus_tag="ERS012477_01847"
     CDS             complement(2762..4429)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /locus_tag="AP598_RS09450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01847"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_000923570.1"
                     /transl_table=11
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNMM
                     LGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGRSI
                     SRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKETYQT
                     SFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDKLLNH
                     KNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYYVLEDI
                     SKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEYNLLTGN
                     NLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKAQFQVRFS
                     KGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKEGKTSIVFD
                     EVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKISNDHSTVSTV
                     RLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            complement(4436..4867)
                     /locus_tag="AP598_RS09455"
                     /old_locus_tag="ERS012477_01848"
     CDS             complement(4436..4867)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /locus_tag="AP598_RS09455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01848"
                     /product="arginine repressor"
                     /protein_id="WP_001034412.1"
                     /transl_table=11
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRDI
                     KELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVKAQ
                     LIDTFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            complement(4860..5675)
                     /locus_tag="AP598_RS09460"
                     /old_locus_tag="ERS012477_01849"
     CDS             complement(4860..5675)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /locus_tag="AP598_RS09460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01849"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_001041073.1"
                     /transl_table=11
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPGE
                     KIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQNS
                     AKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISLSLI
                     LPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKIHQNVLESVTAMAVEAGFSV
                     LGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            complement(5668..6543)
                     /locus_tag="AP598_RS09465"
                     /old_locus_tag="ERS012477_01850"
     CDS             complement(5668..6543)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /locus_tag="AP598_RS09465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01850"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_000743809.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 4.9e-58, bitscore:
                     186.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRPF
                     LLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFGEA
                     MAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQHLS
                     LEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVLDVTA
                     SFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFETESIV
                     SVVESLRING"
     gene            complement(6540..6752)
                     /locus_tag="AP598_RS09470"
                     /old_locus_tag="ERS012477_01851"
     CDS             complement(6540..6752)
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /locus_tag="AP598_RS09470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01851"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_000043230.1"
                     /transl_table=11
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKEL
                     QATLDKAEKTLVKVMQEDGTESDFE"
     gene            complement(6730..8070)
                     /gene="xseA"
                     /locus_tag="AP598_RS09475"
                     /old_locus_tag="ERS012477_01852"
     CDS             complement(6730..8070)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /locus_tag="AP598_RS09475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01852"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_000417469.1"
                     /transl_table=11
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYF
                     SLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDGVG
                     ALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGV
                     DILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIF
                     ESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLTHLQNQEKRMATA
                     VRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQLVQA
                     RTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLMLDTSRIV
                     ARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            complement(8198..8836)
                     /gene="udk"
                     /locus_tag="AP598_RS09480"
                     /old_locus_tag="ERS012477_01853"
     CDS             complement(8198..8836)
                     /EC_number="2.7.1.48"
                     /GO_function="GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="udk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /locus_tag="AP598_RS09480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01853"
                     /product="uridine kinase"
                     /protein_id="WP_001181378.1"
                     /transl_table=11
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKD
                     QSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEP
                     QDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLG
                     VVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     misc_feature    8876..8890
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.39"
                     /tool="antismash"
     gene            complement(8944..9246)
                     /locus_tag="AP598_RS09485"
                     /old_locus_tag="ERS012477_01854"
     CDS             complement(8944..9246)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /locus_tag="AP598_RS09485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01854"
                     /product="bacteriocin immunity protein"
                     /protein_id="WP_000985089.1"
                     /transl_table=11
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSV
                     MANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            complement(9487..10365)
                     /gene="truB"
                     /locus_tag="AP598_RS09495"
                     /old_locus_tag="ERS012477_01856"
     CDS             complement(9487..10365)
                     /EC_number="5.4.99.25"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="truB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /locus_tag="AP598_RS09495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01856"
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="WP_001013237.1"
                     /transl_table=11
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVL
                     PIAVGKATRMVEFMQDEGKIYEGEIILGYSTTTEDASGEVVAETPVLSSLDEKLVDEAI
                     ASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDGQLA
                     RFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAEKVEA
                     GQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLAILEKR
                     GNLYKPRKVFS"
     misc_feature    complement(10378..10387)
                     /note="TFBS match to AbrC3, Antibiotic production
                     activator, confidence: strong, score: 16.22"
                     /tool="antismash"
     gene            complement(10466..13651)
                     /locus_tag="AP598_RS09500"
                     /old_locus_tag="ERS012477_01857"
     CDS             complement(10466..13651)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512660.1"
                     /locus_tag="AP598_RS09500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01857"
                     /product="hypothetical protein"
                     /protein_id="WP_050090478.1"
                     /transl_table=11
                     /translation="MEDDLNYENLMDDVTEAIKKFNLVIFIGAGVSIAQGYPNWNNYIE
                     HLIKYWQGQVLSVSGEKRLGREHHVVFDLISKSSISNKRKVDLVNYELKKVFGEDFEKR
                     RLDFEKGYFKNLLPYSIVNQTVESLASLNAIFITSNYDYEIENHIKRLKNAVVTINDLN
                     EFTKNKNGKLQFGDVLHIHGTPDCDVKYFVSSSADYSKTYLKNRENFENLVTWFKETKP
                     TVLFVGAGLEEDEILSLLCKDSKNYALMKSENTGNQRVDEHYRGVVEGFFSSENHTQII
                     WYGDEFEKLPLFVKKLVADINEKLGTHDFYNQWNNLLNPSINQEEYNKNLDSISNDFKY
                     LSSVLDKVIENDNNQLDQLMLNALLRSETLTVIKKNFVLAFWRFIVKNIEKLSDNEWDV
                     IYKIIYEGSQNYFIDDVFFVYNYAIDNKISSFTNNNKLNELREIISKDGYIVNSNFNKD
                     KTLLGYWLVSAFEQQNRDLYIKEDSEVEVNLNYECVNKLMSILNNPEFLSYNYYSIEHQ
                     LKEYDVVKFLYELVKSKKLFIEEEKFLESDSEDLISTILIQKLLVQLDNEINLDLEFIK
                     RLIDKIDFSNIHFGEELNTFIKEHRSIIREKNIEIPKKPYRNWISSLEGGFVSQFSYLT
                     QENLVEYDESRVLEILVNAEKEQRGSSFLEEKTINETENFFITVLKESNEISKKVSDLL
                     KNHIDDLYPKYKRLYVKIISFPEIEENLRKIVREKYLKRFNKESFDSNDRKFFEYHIKQ
                     QNTDIDIFEKLLSINVNELSTPKGDNKQLDILHFINSEMGSYFQCLISLFINHSSYRDV
                     IIQIINSVTDTDYREFAQGILLNEYNPNRINVTYNTFLGFAYYHSTITIEAADVFTDVV
                     RDILNKKIEDNQILNKVYLVALERVDPTIESFSLSKNNYSQMINIIFTGDYEFRYSKEW
                     LGALFKFDSSANYLVTIFYLLYNENLKKNRFALFIEELSDYLTTYNQKLSLRGMNYKLN
                     HEELNNFDLLKKMFLKLMETDKIENDIFYLDGIKSILPLLSLDDRRNVLQHIQKQNNCP
                     PPEIEELQRIIVN"
     gene            complement(13663..14937)
                     /locus_tag="AP598_RS09505"
                     /old_locus_tag="ERS012477_01858"
     CDS             complement(13663..14937)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /locus_tag="AP598_RS09505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01858"
                     /product="DUF2130 domain-containing protein"
                     /protein_id="WP_001002635.1"
                     /transl_table=11
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQELA
                     LAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEVQA
                     LENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQLKAA
                     SEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGSKGDF
                     IFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLVTMLEA
                     DNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVREQNIDIT
                     HFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQLRLANNKL
                     EDVSVKKLTRKNPTMKAKFEALKGE"
     gene            complement(15033..16292)
                     /locus_tag="AP598_RS09510"
                     /old_locus_tag="ERS012477_01859"
                     /pseudo=""
     CDS             complement(15033..16292)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /locus_tag="AP598_RS09510"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS012477_01859"
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTRDFKFETLQLHAGQVVAPATKSRAVPIYQTTFFVFDDT"
ORIGIN
        1 ggcgacgctg acgtggtttg aagagatttt cgaagagtat aaaaactaaa aaagcagacc
       61 atctaagcct gctttactat tgattcttat ataaatttcc tgtgaacaag gaaaggcatt
      121 tctgataact tattcttcat ccatactcaa gacgctgagg aaggcttctt gcggaacttc
      181 aactgatccg atggatttca tgcgtttctt accagctttt tgtttttcaa ggagtttacg
      241 cttacgagaa acgtcaccac cataacattt agcaagtacg ttcttacgaa gggccttgat
      301 atcagtacga gcgacaatct tgtgtccaat agccgcttgg attggaactt caaattgttg
      361 gcgagggatg attttcttga gtttatcaac gatgagtttc ccacgttcgt aggcaaagtc
      421 cttgtgaacg ataaagctga gggcatccac cttatctcca ttgagaagga tatccatttt
      481 caccagctta gatgggcgat attctgacaa ttcgtagtca aagcttgcat aaccacgtgt
      541 cgaagactta agtttatcaa agaagtcaaa gacaatttca gcaagaggaa tttgatagat
      601 aacattgaca cggttatcat caatatagtc catagtcaca aagtccccac gcttacgctg
      661 agctagctcc attactgctc cgacgaactc ctgtggtacc atgatttgcg ccttgacata
      721 aggctcttca atggtcgcaa tcttagttgg gtctggaaac tcagatgggt tagacacatc
      781 catagactca ccgtcggtca aattaacttt gtaaataaca gacggagctg tcatgatgag
      841 gtcaatattg aactcacgct ctaaacgttc ctggataaca tccatatgga gaagtccaag
      901 aaatccacaa cggaaaccaa atccaagtgc ctgagatgtt tctggttcaa actgaagact
      961 agcatcattc agttgcaatt tttcaagcgc ttcacgcagg tcattgtatt tgtttgattc
     1021 gattgggtag agacccgcaa agaccatagg attcatctgc ttataaccat gtaatggttc
     1081 tgccgcagga ttggttgcca aggtaacggt atcacccaca cgagtatcct gaaccgtctt
     1141 gatagacgcc gcaatgtaac caacatcacc agtcgcaagg aaatcacgac caaccgcttt
     1201 tggtgtaaaa ataccgactt cggccacatc aaaggtctta ctattgctca tgagctgaat
     1261 cttatcacca ggtttgacca ctccgtccat gacacgcact tggaggataa ccccacggta
     1321 agcatcgtaa acagagtcga aaatcaaggc cttaagtggc gccgtcacat cacccgttgg
     1381 tgctggtact ttttctacaa tttgctcgag gatttcttca atcccaatac cagccttggc
     1441 agaagccaaa actgcttcac tggcatccaa accaatcaca tcttcaatct ctgtacgcac
     1501 gcgctccgga tctgcagccg gcaggtcaat tttattaatg ataggcatga tttccaaatc
     1561 attatccaaa gccagataaa cgttggcaag agtttgagcc tcaattcctt gagccgcatc
     1621 gaccaccaaa atagcaccct cacaggcagc tagcgaacgt gaaacttcat aggtaaagtc
     1681 aacgtgccct ggtgtgtcaa tcaagtggaa aatataagtt tccccatctt ttgcagtgta
     1741 attcaactcg atggcattca acttaatagt aattccacgt tcccgctcta gatccatgct
     1801 atccaaaagc tgggcctgca tttcacgact tgaaaccgtc tctgtttttt ccaaaatgcg
     1861 gtctgctaga gttgatttcc cgtggtcaat atgggcgata atagagaagt tacggatctt
     1921 cctctgtcgt tttttcaatt cttctaagtt catgattctc ttcctttcag ggtatctatt
     1981 tattataaat tgtttttgat attttgacaa gaccataccc tgctaggagt actaatcttc
     2041 agcgacaaag ccgtcatttt cgataaagtg gtgttctgtc attccttggt ctgtaaagac
     2101 aatcccgtga aggacaccac cataaacagc tcctccatcc attccaatct tgccatcttc
     2161 tgtagtccaa agctcagatg taccgcgttc ttgctgtaac aaaccataga ccggtgtatg
     2221 accgaagaca atggtttttc cagtatgatt ttcagctccg tggaatggtt ttctaagcca
     2281 tactttttta taatctgttg tttcatgcca gtcgtccaaa gtcaaatcaa tacctgcgtg
     2341 aacaaatata tacttgtctg tctctactac aaatggcatt tgacgaatga attcgaccaa
     2401 gtctgacgct tcagcggcaa cccgcttggc atcttctact ccatcaactg gtgcatccaa
     2461 gggacgacct aggatagagt taatggttgt atctccacca ttgcgacgat aatggtcata
     2521 actttcttct gggtcatcta gccaagtcaa aaacatatac tcgtggtttc cggacaaaca
     2581 gatagcccct tgattgtcca ccaagtcctt gaccatttca agaacacggt gactatcctc
     2641 acctctgtca atcaaatcac ctagaaagag caactggggc tgaccatccc aggttttgag
     2701 aaggtcttcc agcatcccag cttttccgtg aacatctcca attacataat aatctgtcat
     2761 cttatttctc cctgtttctc aacaattctc tggcttgcgt cagggctgct tctgtcacat
     2821 catcacctgc caacatcttg gcaacttcct ccactcgctc ttcgaccgtc aagagacgaa
     2881 cagtcgaaac cgttgaatgg tcattactaa tcttctcaat aaagaattga taatctgcaa
     2941 tcgcaattac ttgtggcaaa tgggagatag ccaaaacctg accatgctga ccaattttat
     3001 gaattttctg agcaatagct tgagcaacac gacctgaaac tcccgtatcc acctcatcaa
     3061 agacaatgct agtcttgcct tctttacgtg aaaaggcaga cttaatggct aacatgagac
     3121 gagataattc ccctccagaa gcaaccttaa ccaagggttt aaagtcttct ccagggttgg
     3181 ttgaaatata aaactcaacc atttcatttc cctcacgact gaattttccc ttactaaaac
     3241 gaacctgaaa ctgggctttt tccatataaa gatcttgcag ttcttgttta atctcagctt
     3301 cgagttgctg agccaaatta tgacgagcag aagcaagttg acctgccaaa ttgacaagat
     3361 tgacttccaa cttcttaagc tctgcttcca tgtcctcaga cgaaagatta ttgcctgtca
     3421 agagattgta ttcttccgta atcttggcaa aataaagcaa aacatcatca acagtcccac
     3481 catacttacg agtaatagta tgaaggaggt ccaaacgatt ctcaacctgc atcaggcgat
     3541 tgccatcaaa atcaaggtcc tcaatgatag cttccaaacg tttgctaatg tcttctaaaa
     3601 catagtaggt ctcagacaga gagcttgaaa tttcacggta ttcaggatca tactcttcga
     3661 cactttccat gtcattcata gctgaacgaa cattggccag acttgaaaaa tcttcattgt
     3721 ccaacatact gtaggcattg gtcagtgtat ccgcaatatt tttgtggttg aggagtttat
     3781 ctcgctcttg attgagagcc aagtcttctc cagcctgcaa gtttgctgcc tcaatctctg
     3841 ccatttgaaa ttccaacatt tcgatacgtg ccttgtgttc ctgttggttt ttcttgactt
     3901 ccagaacctg cttgcgcatt ttccgatagg catcaaaact cgtttgatag gtttctttca
     3961 agtcccaaaa agcggcatca ccaaattcat ccaacatctg gatatgcagt tggggacgca
     4021 ttaactcctc atggtcatgc tgaccatgaa tatctacaag atgttgccca atagctcgca
     4081 aaacagacag attaaccatc tgaccattta cacggctgat actacgacca ttttgcaaga
     4141 tttcccgacg gatgataatt tcatcaccta attctaaacc ttgctcatca aaaatttcct
     4201 gtaaaaggcg actattctca actgagaaaa gcccctcaat ctctgccttt ggtgcaccat
     4261 gacgaataac atctgtcgtc gcacgagctc ccaacatcat attcatggca tcaatgataa
     4321 tcgacttccc tgcacccgtt tcaccagtca ggacagtcat ccccttttca aaattgaggg
     4381 aaatagcctc aataatggca aagtttttta tcgaaatttc aagtaacata tagacctacc
     4441 aattttttac ttgttcaaag atttcctctg ctagacttcc acttctggca atgactaaaa
     4501 tcgagctatc atcagtcaaa caactaaaaa tcttgtctgc aaaagtatcg attaactgag
     4561 cttttacaaa agccgtattt cctggaataa cttggagatt gatcatctta tccatcaatt
     4621 cagccgattc gatattgtct tcagccagtt gcagactttt tacgattgat tttggtaatt
     4681 cgtagacata ggtgttgtct ctcaaaggaa ttttgacaat acctaactct ttgatatctc
     4741 gggataccgt cgcctgagtg gcagtgatac ctgcttcttt caaatgttct acaatttctt
     4801 cttgcgtgcc gatttgataa tctgtcacca atcttctaat tttttcaagt ctttcttttt
     4861 tattcatttt taaattgact atgcgccctc tctactgctt ctttaatctc agcaagaatc
     4921 tgattgcttg ctgacttttc ttttttcaaa tacgctaaaa attcaatatt tccatgtcca
     4981 ccttggatgg gagaaaagtc caagccaagg actgaaaaac ctgcctctac tgccatagct
     5041 gttacagatt caaggacatt ctgatgaatc ttagcatctc gaataattcc atttttccca
     5101 atctgctcac gtcctgcctc aaactgaggt ttgacaagtg ctaccacctg accttgatca
     5161 gccaagacac ggtgcaaggc tggcaaaatc agactaaggg aaatgaaact cacatcaata
     5221 ctggcaaagc tcggctcctg ctcgaaatca gtcttttcag catagcgaaa attgaactgc
     5281 tccatgctga caactcgtgg gtcttggcgt aatttccaag ccaactgatt ggtaccaaca
     5341 tcgactgcaa agaccaactt ggcactattc tgtagcatga catcggtaaa acctccagta
     5401 gaggccccga tatcaatcgt agtcgcgcca tccaccgaca aatcaaagac ctgcaaggcc
     5461 ttttccagtt tcaaaccacc acggctgaca tacttgagtt tctccccctt gagttttaat
     5521 tcggtgtcat ctggaatttt ctctcctggc ttgtcaaacc gttctccatt aaggactgct
     5581 acgactagac cagccatcac acctcgcttg gcctgctctc tcgtttcaaa caacccctgt
     5641 ttataagcta gtacatccac tctttcctta gccattgatt ctcaaacttt ctactacact
     5701 tacaatcgat tctgtttcaa agggaacctg ctgggcaatt tcttccaatt tttcattagc
     5761 ttgatccagg gtttggttac aaaaggcaat ggactcttcc aagcccaaca aggcaggata
     5821 ggttgatttt tctgcctgca gatccttttg aggtgtctta ccgatttcct caaaactagc
     5881 tgtcacatcc agtacatcat ctctgacttg aaaagcaagt ccaatcaatt cacccacagt
     5941 tttcagcttc acctgcattt caggtgacaa ttcagctata atagctgccg cttggaaggg
     6001 ataggctagt aacttcccag tcttattggc atgaatagtc tgaagttctt ccagagacaa
     6061 gtgctggtgt tcgccctcca tatccaaaac ttgccctgcc accataccca gactacctga
     6121 agcaagggat aagttggcaa tcaagtccac cttgatctga cttggcaaat ctgcctgcgc
     6181 aatcaaggca tatgggtcta agaataaggc atctccagcc aaaatggcca tagcttcacc
     6241 gaatttcttg tgattggtta accgccctct tcgataatcg tcatcatcca tagcaggaag
     6301 gtcatcgtga atcaagctcc ctgtatgaat catctccaag gcagtagcta cctgcgcgtg
     6361 agcaggtttg atggcaacct gcaaggcttc cagaacttct aacaagagaa aaggccgaat
     6421 acgcttgcca ccagcatgaa tagaatagag aacagactcc cgtaaactag aggcaaactg
     6481 ctggtctcca taaaaatctt ccaaagccga ctcgacaaga gctaattttt cttgcttttt
     6541 cattcaaaat cactttctgt tccgtcttct tgcatgacct tgaccaaggt cttttcagcc
     6601 ttgtccagcg tagcttggag ctcttttgac aagaccatgc ccttttgaaa ggcagtaatc
     6661 gcatcttcca gagcaatttc accattttcc aaactttgga caatggtttc cagttctgct
     6721 agattttcct caaatttctt ttgttttgac atctttaacc tctaattcta cttgaccatc
     6781 tcgcatcaaa agcgttactt ggtctttttt cttcaaactc tcaaccgaat ctacaacgga
     6841 ctcttctttt ttgacaatag cataaccacg cgccacgatt cggctagtat ccaacatgag
     6901 caaagcttcc gaaagtcgct tggcctcagc aaccttggcg tcataaacta acgccatttg
     6961 gctacctaag agcttgtcca actgtcctaa acggtcttga tagcgttgga ttttggtaac
     7021 aggtgataat tgtactaatt gatgagttct tgcttgaact aattgtttgt tatcagaaat
     7081 ccgagttcgc aaactttgct tcaaacgcag ttgcagttgg tccaagcgtt gcaaataacc
     7141 gtcatacaag cgctcaggtt gtctaaagat aacagactga ctgcattttt tcaaagcctc
     7201 ttgtttctta gatagaacat ttcggactgc cgttgccatc cgtttttcct gattttgcaa
     7261 atgagttaat acatccaact tggtcacagg tgttgccagt tcagccgccg ctgttggcgt
     7321 tgcagcgcgt cgatctgcca caaaatctgc caaggtcaca tccgtctcat gccccacact
     7381 agagataact ggcaaacgag attcaaaaat agctcgtacc acaatttctt cgttaaaggc
     7441 ccagagatcc tcaatagaac cacctccacg accaataatg agcaaatcca aatcgtcccg
     7501 ttgattagca cgcgcaatat ttctagcaat ttcctccgca gccccttcac cttgaacctt
     7561 ggtaggataa agaaggatgt caacacctgg gaatcgcctg ctgacggtcg tgataatatc
     7621 tcgaataacg gctccactac ggctggttac taccccaatt ctcttagaaa attggggtag
     7681 agcttgcttg aagcgttctt gaaacaggcc ttcttctgtc aattttttct taagttgttc
     7741 aaactgaatc gcaagcgccc caaccccatc aggctcagct ttttcaatga tgatggagta
     7801 gctaccactt ggttcataga cctgtacacg cccaatcaca ttgatcttca ttccttcttc
     7861 caggtcaaac cctaatttct gataaatccc agaccagatg gtcgcttgaa taactgcatg
     7921 gtcatccttt agggagaaat attggtgagt aggtcgttta cgaaagttgg aaacttgacc
     7981 agttaaatag acccgttcca agtatgggtc tttatcgaat ttcattttca gatatttggt
     8041 caaagttgtt accgataaat acttttccat ctccacctac tattcattta cttgctcttt
     8101 tatgggtatt attataccaa aaatatgcct aaaaatctcc atttatgtac cattatgagg
     8161 gaaaaataga aaaaggaggc aaggcctcca catgtaatta tttgctgttt cgagcttctt
     8221 ccaaaatctt tgcaatcttg gtcgtcaaca ggtcgatagc cacggtattg ctaacccctt
     8281 caggaatgac gatatcagca taacgcttag ttgactcgat aaactggtgg tacattggtt
     8341 tgaccacacc taagtactgg ttgataacgc tatcaaggct acggccacgt tcctccatat
     8401 cacgcttgat acgacgaata atgcgcacat cgtcatccgt atccacaaaa atcttgatat
     8461 ccatcaaatc gcgcagacgc ttgtcctcca agaccaaaat gccctcaacg ataaagacat
     8521 cttgaggctc ctgacgatag gtcttgctac tccgtgtatg ctctgtatag tcgtaggtcg
     8581 ggatgtccac cggacgccct gccaacaatt ccttaatctg ctcgatcatc aagtctgtat
     8641 caaaggcaaa aggatggtca tagttggttt tgacacgctc ttcaaaggtc aaatgagact
     8701 gatccttgta gtatgaatca tgctcaatca tggaaatctt ttcatcagga aaatgcgata
     8761 aaatggctct tgaaacactg gttttaccac caccagaacc acctgtcact ccaataatga
     8821 ttggtctatt ttgcatgcta tcctccgtta ttttatccgt cgtctattct atcacatttt
     8881 ttacaaaatt tatagtctca tcagcaaaaa acaccagagt cttccctctg atgttcgaca
     8941 gttttaacga aagccctgta gggtttgagc aagcatctgc aagaaagcca gtctccctct
     9001 ttcctggcta ggagctttgg caatccataa accaaaatca atgacagact taggtgcctg
     9061 gtaatgatgc gtcatgaggt aaagtgacaa cccttgactc aaattggcca tgaccgattg
     9121 gtatttttca tttctgtcta aattttgtat agcaagacga aacaggtgac tcaactcact
     9181 attttcattt atttcttttt gttgaagaag ttgctccacc ctttctcgaa actcatttcg
     9241 catcatggaa ttatcacacc aaatcctggg cctaagttcc caccagaacc tgtaatggac
     9301 tctaaatatt tatctgaaag aattttaaat tgcttcattt cacacctcta aatttctata
     9361 tagattattt gagtacctac aactcgcaac aattggaata ttataattcc caaaaccatt
     9421 ctactattag tatggggttt tatcaagcaa ttgttatcta tcacccgatt tttattccta
     9481 aacgatctag ctaaaaacct tccttggctt atagagattg ccccgttttt ctagaatggc
     9541 taacaattta tcatcttcaa aggcagccag ttctttgtcc gtttggtcta gctcaataaa
     9601 acgaccaaag cgaacttctg tagcctcttc tggagttagg aaaactttga caaggtcacc
     9661 tgtcccaatc tctaaaggat ggagaaaatc taattgccca gcctctactt tttcagcaat
     9721 ttcctccaag gcaagagcgt cttctaattg taagccagca gcactagtac gagtcaaatg
     9781 ggacatatga gccgcataac caagcttttc acccaaatca actgacaaag tacggatgta
     9841 agtcccttta ctgcatttta cacgaaaagt gaatcgggca agttggccat cataagaaat
     9901 cggacttgtt cgttcaaatt gataaatggt cacctgacgt tctggacgct ccacttcctg
     9961 accagcacgc gcatactcat agagcttgcg accattaacc ttaactgccg aatacatagg
    10021 gggaatctga gtaataggcc cagtcaagct agcaatcgct tcatcaacaa gcttttcatc
    10081 caatgaagac aaaacagggg tttctgcgac cacttcccca ctagcatcct cagtcgtcgt
    10141 ggaatagccc agaatgattt ccccctcata gatcttaccc tcgtcctgca taaactcgac
    10201 catgcgtgtc gccttgccaa ccgcaatcgg caaaacaccc accacatccg gatccaaggt
    10261 tccaccatga ccaattttct tggttcccaa aatcttacgc agtttaaaaa ccgcatcatg
    10321 cgaggtcatt cctgcttctt tttttaagtt gataataccg ttcatttttg ctttctactc
    10381 ccccttcagt gcttcgaact tcgctttttt ccgggccaat ttttactgag gcgtcgtcta
    10441 ccttttattc tcttttttac aaattttaat taactataat tctttgtaat tcctcaatct
    10501 ctggaggagg acaattgttc tgtttttgaa tatgttgtaa tacatttcgt ctgtcatcta
    10561 aagataataa tgggagtata cttttgatgc catctaaata aaaaatatca ttctctattt
    10621 tatcggtctc cattaatttc agaaacattt ttttcaacaa atcaaaattg ttaagttctt
    10681 catgattcaa tttataattc atccctcgta aagataattt ctggttataa gttgttaagt
    10741 aatcactcaa ttcctctata aacaaagcaa atctattttt tttaagattt tcattatata
    10801 ataaataaaa aattgtcacc aaataatttg cacttgagtc aaatttgaat aatgctccca
    10861 accattcttt agaatatcta aattcatagt ctcctgtaaa aatgatgttt atcatttgac
    10921 tatagttatt ctttgataaa gaaaatgatt caatagttgg atctaccctc tctaaagcaa
    10981 ctagataaac tttattaaga atttgattgt cctcaatttt tttgtttaga atatccctta
    11041 ctacatctgt gaaaacatcc gcagcttcga tagtaattgt agaatgataa tacgcaaatc
    11101 ctaaaaaggt gttgtaagtt acattgattc tgtttggatt gtattcattt aataaaatac
    11161 cttgagcaaa ctccctataa tcggtatctg ttactgaatt tattatttga ataattacat
    11221 ctctataact tgaatgattt ataaataatg atattaaaca ttgaaaatat gatcccattt
    11281 cactatttat aaaatgaagt atatctaatt gtttattatc accttttggt gttgagagtt
    11341 cattcacatt gatactaagt aatttttcaa aaatatctat atccgtattt tgttgtttta
    11401 tatgatattc aaagaatttc cgatcgttag aatcaaaact ttctttgtta aatcttttta
    11461 aatatttttc tctaacaatc tttctcaaat tttcttctat ttcaggaaaa ctgataattt
    11521 ttacatataa tctcttatat tttggatata agtcatctat atgatttttc aataaatcag
    11581 aaactttttt agatatttca tttgattctt ttaaaacagt aataaagaaa ttttccgttt
    11641 catttatcgt cttttcttcc aaaaatgaag aacctctttg ttccttttcg gcgttgacta
    11701 atatctctaa tactctagat tcatcgtact ctacaagatt ttcttgagtt aaatatgaaa
    11761 attgtgaaac aaaacctcct tctagtgaag atatccaatt tctataaggt ttttttggta
    11821 tttcaatatt tttttctcta ataatacttc tatgttcttt gataaaagtg tttaattcct
    11881 ctccaaagtg aatatttgaa aaatcaattt tatcaattaa cctcttgata aattctaaat
    11941 ccaaattaat ttcattatcc aattgaacaa gcaatttttg aattaatata gtacttatta
    12001 agtcttcaga atcactttct aaaaactttt cctcttcaat aaataatttt ttggacttta
    12061 caagctcata aagaaattta acaacatcat actcttttaa ttgatgctct atagagtagt
    12121 aattataact taaaaattct ggattattta gtatggacat taatttgtta acacattcgt
    12181 aatttaagtt aacttctact tcactatctt cctttatata taaatcacga ttttgctgtt
    12241 caaaagcact tactagccag taacccaaaa gagttttatc tttattaaag ttagaattaa
    12301 cgatatatcc atctttggat ataatttctc tcagttcatt aagcttatta ttatttgtaa
    12361 aactagaaat tttattatct atcgcataat tatagacaaa gaatacatca tctataaagt
    12421 aattttgaga gccttcataa attattttat aaatcacatc ccactcatta tcacttaact
    12481 tttcaatatt cttaacaata aacctccaaa atgcaaggac aaaatttttt ttaattactg
    12541 ttagagtttc actccgaagc agagcattta acattagctg atctagttga ttattatcat
    12601 tttcaataac cttatctaaa acagagctta gatacttaaa atcattagaa atactatcta
    12661 gatttttatt atactcttct tgatttatag aaggattcaa aagattgttc cactgattat
    12721 aaaaatcatg tgtgcccaat ttttcattaa tatcagcaac taattttttt acaaaaagag
    12781 gtagtttctc aaattcatct ccgtaccaaa taatctgagt atgattttct gagctaaaaa
    12841 atccttcaac aacacctcta taatgttcat caactctctg attacctgtg ttctctgact
    12901 tcatcaaggc atagttctta ctatctttac aaagtaaaga taaaatttca tcttcttcaa
    12961 gacctgctcc aacaaataaa acagtaggtt ttgtctcttt aaaccatgtt actaaatttt
    13021 caaaattttc cctatttttt aaataggttt ttgaataatc tgcggatgaa cttacaaaat
    13081 actttacatc acaatctggt gttccatgga tatgtagaac atcaccaaat tgtagtttcc
    13141 cattcttgtt cttagtgaat tcattgagat cattaatagt aactacagca ttctttaaac
    13201 gtttaatatg attttcaatt tcatagtcgt agttagaagt aataaatatt gcattcaaac
    13261 ttgctaaaga ttctactgtt tgattaacta ttgaatatgg taatagattt ttaaaatatc
    13321 ctttttcaaa atctagtcgt cgcttttcaa aatcttcacc aaaaactttt tttaattcat
    13381 agtttacaag atccacttta cgtttattac taatactaga tttgctaatt aaatcaaaaa
    13441 ctacgtgatg ttctcttcca agcctttttt caccacttac cgataaaact tgtccttgcc
    13501 aatacttaat aagatgttca atataattgt tccaattagg ataaccttga gcaattgaaa
    13561 ctcctgcgcc aataaaaatt actaagttaa acttttttat agcctcggtt acatcatcca
    13621 tcaaattttc ataattaaga tcatcttcca taacttattt cctcactccc ccttcaatgc
    13681 ttcgaacttc gctttcattg ttggattttt ccgggtcaat tttttaacag agacatcttc
    13741 caatttgttg ttagctagac ggagttggtt ttcagatgta gtcaggaatt tcttaacctc
    13801 ttccatgcgt ttgatggcct tgtcgatttc atcaatagct tttccaaagt tagtcgaagc
    13861 tgaattatag ttcttagcaa aagctagctt aaaggcatcc aagtcttcct caaaatgcgt
    13921 aatgtcaata ttttgctcgc gaaccaaggc caactcctgc ttgtatttta gggaatttag
    13981 cgccgcatta cgtaagagac caatcaattg gataaagaat tgaggacgaa caacatacat
    14041 tttttcatac tcgtgactga cgtcaacaat ccctgtgtta aagtagtcat tatcagcctc
    14101 aagcatggtc accaaaacgg catactcaca gttcttctcc cgacggtcct tgtccaattc
    14161 cttgtaaaaa tctgcattct tgtgcttctt ctctgttccg tccgcttcgt ttttcatctc
    14221 aaacatgata gaaatgattt caactccatt ttcatcacac tcacggaaga taaagtcccc
    14281 tttagaccca cgcgaagaga ccttgttatc cttctcaaag taagcatttg gaaaggcgaa
    14341 actacgaacc ttgttaaact cactctctgc atactgttct aggctttccc caatcgcttt
    14401 tgtagattgt tgagccttaa aattcttata aaactcgact tgttcactgg ctgctttgag
    14461 ctgggcttcg tagttttgct taacagaagc caaagacaac tcattttcct tttcttgcag
    14521 taggagctga tttttgacct gattgcgttc tttttctagg tcagaaaggg tcttttgcaa
    14581 ttgattttca tgctccaaac gcaaggtcgc caactggttt tccaaggcct gtacttcctt
    14641 gtccttagcc aataaggcct gatggcttgt ctgttcaact tctttcttgg ccaattcttt
    14701 ttctgtatca aagttttgga tttgactctg caattgcgca atttcttgat ccttctgagc
    14761 cagtttagtc tgttgctcat tcatagcctt ttgctcagcc aaggccagtt cctgcctcat
    14821 cctatcgtgt agttccttat caaactctgc cgttctcact tgggacaaaa gttcagcata
    14881 ctggctttca tttactgtaa agacttcccc acagttggga catttgattt cgttcattac
    14941 attcctcttt ctagacttct gtaaccatta tatcatgcct gagggaaaat caaaaacagt
    15001 gagtcaaaac ccactgttta tcttctttta ctttaaattt tttccaaggc caagcgtaag
    15061 tcttcaatca aatcttctac attttcaaga ccgatagaca agtggatttg atttggtgtg
    15121 acacctgctg cttctaggtc tttttctgac aattgaccgt gagtgattgt tgctggatgg
    15181 acaacaagcg atttagcatc tgccgcgttt gcaaggtcag aaaagatttc taaattatca
    15241 atgaccttgc gtgcttcctc ctcgtcacct ttgacgtgga aggtaaagat tgaaccgaca
    15301 ccttttggca agtatttctc agccaaggca taataaggac tatctgcaag ttttggataa
    15361 tttacctttt ctaccttagg atggttgaca agaaaatcaa caattgtctc agcattttgt
    15421 acatggcgtt ccacacgaag tgaaagggtt tcaagtcttt gtagcaagag gaaagcattg
    15481 aatggtgaca aggctgcacc tgtatcacga agcaattgaa ctcgaacagc tataataaag
    15541 gctgctgcac ccacatcatg agtatagctc aaattgtggc agcttggact ctcgtcaaca
    15601 aattgaggga atttccctga agccgtccag tcaaaacgac cactatcgac aattattcct
    15661 ccaatagttg taccatgccc accgataaac ttagtcgcag agtgaatggc aatgtcaacg
    15721 ccatgagaga agacgttaat caaataaggt gttgcaaaag tattgtctga cacaagtggg
    15781 atttgatgtt tatgagcaat ctctgccagt ttttccaggt ctggaatatt aatcaagggg
    15841 ttacccaagg tttcaatcaa gacaagcttg gtattgtctt tgatagctgc ttctacttcc
    15901 tccaaattat caacatcgac aaaggttgtt gtgataccat aacgaggaag gggttctttc
    15961 aaaagattga aggttccacc gtaagtagtc gaagcagcca ctacatgctc accagcatgg
    16021 gcaagcgcca aaatcgtata agtcactgca gtcatacctg atgctgttgc tagcgcttca
    16081 acaccacctt caagggcagc tgttgtagga ttggtgatac gagtataaat gttccctggt
    16141 ttcctcaagg caaacagatc ggcaccttcc tacgtgtcat caaaaacaaa aaatgttgtt
    16201 tgataaatcg gcactgcacg agacttagta gctggagcca caacttgacc agcatgtagt
    16261 tgtagagttt caaatttaaa atcacgagtc ataaggtgac ctccatatta ttttattaag
    16321 gatattgtag caccttgagt tatagtttac aaatatcagt tttctatatt ttgatataag
    16381 aaatagctat taccttattt tgaaaatgaa aaaagcacga ctcaatcgtg ctcattttct
    16441 taatctacat aagtatcttc gtttttattg aggaaggcat atggaagacc catcaagagg
    16501 cctcctccga taaagtttcc gatgaaagtc acaccccagt ggc
//
