LOCUS       NZ_LGRV01000007        24719 bp    DNA     linear   CON 02-MAY-2024
DEFINITION  Lysinibacillus contaminans strain DSM 25560 Scaffold2, whole genome
            shotgun sequence.
ACCESSION   NZ_LGRV01000007
VERSION     NZ_LGRV01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Lysinibacillus contaminans
  ORGANISM  Lysinibacillus contaminans
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae;
            Lysinibacillus.
REFERENCE   1  (bases 1 to 517302)
  AUTHORS   Liu,B., Wang,J., Zhu,Y., Liu,G., Chen,Q., Chen,Z., Lan,J., Che,J.,
            Ge,C., Shi,H., Pan,Z. and Liu,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-JUL-2015) Agricultural Biological Resources Research
            Institute, Fujian Academy of Agricultural Sciences, No. 247, Wusi
            Road, Fuzhou, Fujian 350003, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 150.0x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001278945.1-RS_2024_05_02
            Annotation Date                   :: 05/02/2024 02:42:19
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,940
            CDSs (total)                      :: 3,858
            Genes (coding)                    :: 3,804
            CDSs (with protein)               :: 3,804
            Genes (RNA)                       :: 82
            rRNAs                             :: 3, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 1, 2 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 54
            CDSs (without protein)            :: 54
            Pseudo Genes (ambiguous residues) :: 0 of 54
            Pseudo Genes (frameshifted)       :: 18 of 54
            Pseudo Genes (incomplete)         :: 39 of 54
            Pseudo Genes (internal stop)      :: 18 of 54
            Pseudo Genes (multiple problems)  :: 15 of 54
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:35:59
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 180346
            Orig. end                         :: 205065
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            LGRV01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24719
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..24719
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24719
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:14719](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14719
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            819..1346
                     /locus_tag="AEA09_RS17105"
                     /old_locus_tag="AEA09_17135"
     CDS             819..1346
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /locus_tag="AEA09_RS17105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17135"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_053585165.1"
                     /transl_table=11
                     /translation="MTDDLITSLYKEKAVIIKKYLIKNGCSLLDAEDIVQGTFVKAIQY
                     MVELHEKNLSAWLFKVALHAYYDLCRKNNRFPSCSLEDQNQFFTGLADELDGEKLLLSK
                     EKAEEITQVVNMLNPNQRNLLLLKYEMELSYKEIAELTDMDEKTIKTYLYRARLAFKKK
                     WEETNNEKIKDR"
     gene            1324..2292
                     /locus_tag="AEA09_RS17110"
                     /old_locus_tag="AEA09_17140"
     CDS             1324..2292
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025164.4"
                     /locus_tag="AEA09_RS17110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17140"
                     /product="anti sigma factor C-terminal domain-containing
                     protein"
                     /protein_id="WP_053585166.1"
                     /transl_table=11
                     /translation="MKKSKIDDLFDFENVDTEKMLKEAKGKSYARIILISLSMAIYIFG
                     LIYLEKIQITPFLLDNKISEIDSYYSVYGANTHLGIWDEEYRFIGSSATAPKYKIIDGK
                     PVSLGEVKVPWKVNFNEFSLNSNWPTTDTKDVFTYDGVRKLQFYHPSVTYEEYKNDLSL
                     IAEIPDFKKIEMGISFDKPYTLQEVQNMLPKNVKFQWAWVDIYDETYLQGLKSSDGTPS
                     VVVSEEYAAGFHLYDQVGEAIKNPKEKFVENLELALRNKSDYYNDLKTIDDFLKQENEA
                     INTDNIMIVGAVITGSPKDILSVQHKEYVKAAVLGAVVDKY"
     gene            2304..2663
                     /locus_tag="AEA09_RS17115"
                     /old_locus_tag="AEA09_17145"
     CDS             2304..2663
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AEA09_RS17115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="AEA09_17145"
                     /product="hypothetical protein"
                     /protein_id="WP_053585167.1"
                     /transl_table=11
                     /translation="MVKVFMENRPILFGGLAFGLASLVLNCLYIIFFNMAHVYDVIHVI
                     PIIFLMDPIVEKIGYMATPFMLLPIAIILDFICGLLFGWIAKKLTKTLLAYVVALLLLF
                     GFYWVVITYQWILIL"
     gene            3456..4571
                     /locus_tag="AEA09_RS17120"
                     /old_locus_tag="AEA09_17150"
     CDS             3456..4571
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244: amidohydrolase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225542.1"
                     /locus_tag="AEA09_RS17120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17150"
                     /product="M20 peptidase aminoacylase family protein"
                     /protein_id="WP_053585168.1"
                     /transl_table=11
                     /translation="MNEDLQRLQPKLVEIFKHLHEHPEISWQEQQTTKYIANILKDADM
                     EPHVFEDIPGLYVDIGKGTPKVGFRTDMDALWQDVDGVFKANHSCGHDGHMTMAIGTAL
                     LLKEMESVLSGAVRIIFQPAEEKAEGAHALVQKGLIDDLDYLFGVHVRPLKELPDGTHA
                     PAIYHGAAKIFTGTIIGEDAHGSRPEHGINAIEVGAAIVEGLQKIWTDSNVSASAKMTQ
                     FQAGGSSANIIPGKATFSIDARAQTNEAMLSLTKGIERVKTSVEILYGAMIDLRADVHV
                     VAALVNEDAVEIMRTAIIEVVGEEACAPPVVTPGAEDFHFYTYERPNLKATMLGFGCGV
                     TPGLHHPKMTFNRERLMTGVSIITRAILRAL"
     gene            5610..6521
                     /locus_tag="AEA09_RS17130"
                     /old_locus_tag="AEA09_17160"
     CDS             5610..6521
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008176292.1"
                     /locus_tag="AEA09_RS17130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17160"
                     /product="LysR substrate-binding domain-containing protein"
                     /protein_id="WP_053585170.1"
                     /transl_table=11
                     /translation="MELRDLNIFMAIVKHGSYTKASEVLFISQPTLSKSVKRLENELQA
                     QLLQRTTRQLQVTDIGSVVYEHGQKILYNLQELGQSIQDIRDVQLGTIKLGIPPLIGTL
                     FFPEIARTFHQQYPKVTLELVERGAKLISELVHSGQVDVAFVVLPIEEPAFTIEQFIED
                     DFVLYVHKEHPLAQCAEVSVEELKNEKFILFSNEYALHDFVIRACENGGFSPDIVYKSS
                     QWDLIVELIGLNLGLTILPRAIYEKQSNPNVKIIPLTNSLIWKLGLVSLKDRYKSFALQ
                     ELVKMIRTESWSWQSFIPLKNE"
     gene            6593..7300
                     /locus_tag="AEA09_RS17135"
                     /old_locus_tag="AEA09_17165"
     CDS             6593..7300
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010493529.1"
                     /locus_tag="AEA09_RS17135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17165"
                     /product="CoA transferase subunit A"
                     /protein_id="WP_053585456.1"
                     /transl_table=11
                     /translation="MGMTKVKRSFEEALVDLKDGQTVIVGGFGLCGIPEKAIEAIRQKG
                     TKDLTVVSNNCGVDDFGLGLLLANKQIKKMVASYVGENKIFEQQFLSGELEVELTPQGT
                     LAERIRAGGAGIPAFYTATGVGTPIAEGKPTKEFDGKVYLEERAIVGDYAFVKAWKADT
                     LGNLVYRKTARNFNPLAATAGKITIAEVEEIVEVGALNPDEIHTPGVYVQHVLVGENYE
                     KRIERLLTAKEVG"
     gene            7303..7953
                     /locus_tag="AEA09_RS17140"
                     /old_locus_tag="AEA09_17170"
     CDS             7303..7953
                     /GO_function="GO:0008410 - CoA-transferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012370073.1"
                     /locus_tag="AEA09_RS17140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17170"
                     /product="3-oxoacid CoA-transferase subunit B"
                     /protein_id="WP_053585171.1"
                     /transl_table=11
                     /translation="MSETRDRIVRRAVQEIENGMNVNLGIGMPTLVANEIPADYQVLLQ
                     SENGLLGIGPYPTEAEVDADLINAGKETVTAVAGASYFDSAESFAMIRGGHIDLAILGG
                     MEVSETGDLANWMIPGKMIKGMGGAMDLVQGAKRVIVIMDHMSKHGESKVKKECTLPLT
                     GQGVIHRLITDLAVFDFTPSGMVLVEKIADLSVEEIRARTEASFTVSDGLKVY"
     gene            8120..8767
                     /locus_tag="AEA09_RS17145"
                     /old_locus_tag="AEA09_17175"
     CDS             8120..8767
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003352525.1"
                     /locus_tag="AEA09_RS17145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17175"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_053585457.1"
                     /transl_table=11
                     /translation="MVKKTLKQRIVEASLILFQQDGYHGVTVDRIVEYIGASKGGFYHN
                     FKSKDELLYEIHDVFISYVIKKSQDAYDQYNTPITRLCAMIQTLTEVFDVYQAHITVFY
                     EESGSLPEVYSELIHKKRNQYRGILQKVIVEGQQTNDFRSELPGTIVTMAIVGMINWTY
                     KWYKQTGPLTMEEITVVFMDMILHSIVTEQAREEATQFMIAMKPATETGFIN"
     misc_feature    complement(8123..8138)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: medium, score: 25.99"
                     /tool="antismash"
     gene            8826..9968
                     /locus_tag="AEA09_RS17150"
                     /old_locus_tag="AEA09_17180"
     CDS             8826..9968
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015864021.1"
                     /locus_tag="AEA09_RS17150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17180"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_053585172.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.4e-41, bitscore:
                     136.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 3.8e-28, bitscore:
                     92.4, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4e-52, bitscore:
                     171.2, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNFELTKEQEMIRDMVRDFAEKEIKPYAREVDETSTMRIESFEKM
                     AELGLMGIPFPEEYGGSGGDTVSYAIAVEEIGRACGGTGLSYAAAISLGAAPIYNFGTE
                     EQKREWLVPLAKGETLGSFGLTEPNAGSDAGGTLTTAVVDGDDYVINGEKCWITNAGHA
                     RQIIVTAVTGKREDGKKIISSIIVPTNTPGVTINCNYDKMGVRGSNTCEIVLQNVRVPR
                     ANLLGDEKRGFSQFLNTLDGGRISIAALSVGIAQAAYEKALQFAKERKQFGVSISKFQA
                     IQFKLADMAMEIELARTLVHKAAWLKDQKKPFGKEAAMAKLFASEMGFRTCNQAIQIHG
                     GSGYMKEYDVERHLRDIKLMEIGEGTSEIQRLVISRLIGC"
     gene            10001..11635
                     /locus_tag="AEA09_RS17155"
                     /old_locus_tag="AEA09_17185"
     CDS             10001..11635
                     /NRPS_PKS="Domain: AMP-binding (13-445). E-value: 1.6e-103.
                     Score: 338.4. Matches aSDomain:
                     nrpspksdomains_AEA09_RS17155_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012292658.1"
                     /locus_tag="AEA09_RS17155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17185"
                     /product="AMP-binding protein"
                     /protein_id="WP_053585173.1"
                     /sec_met_domain="AMP-binding (E-value: 1.1e-109, bitscore:
                     361.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAELVYQTIGQLLDEQSEKYPKREALVYADRDLRMTYEEFNRQSR
                     LVARGLMALGIEKGDHIAVWTTNVPEWVQLQFSTGKMGAPLVTVNTNYRASELEYLLKQ
                     SDSKTIILIENYRDHSFINTLQELCPELEHCEPGNLQSKRLPLLKNVILIGDAKYPGVL
                     NWSDVLAAAEQVKEEQLDIRQGTLHYDDVINIQYTSGTTGFPKGVMLTHFNLVNNAVNI
                     AECMKLTHEDRLCIPVPFFHCFGCVLGTLAITTSGGTMVPVQEFSPEEVLRTVEKEKCT
                     ALHGVPTMFISELNLPNFSSFNLSTLRTGIMAGSNCPVEVMKAVIEKMGMRDITISYGQ
                     TESSPVITQTKADDPFNLKVETVGRALPNLEVKIVDPDTNEEVAPNEQGELCTRGYHVM
                     KGYYNNPEETGLAIDRDNWLHTGDLATKDEAGYIRVTGRLKDMIIRGGENLYPREIEEF
                     LYTHPKIFDVQVAGVPDPVYGEEVAAWIILREGEQATAEDIRDFCRNKISKQKIPKHIF
                     FIDSYPMTASGKVQKFKLRDEFVIAVR"
     aSDomain        10040..11335
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AEA09_RS17155_AMP-binding.1"
                     /evalue="1.60E-103"
                     /label="AEA09_RS17155_AMP-binding.1"
                     /locus_tag="AEA09_RS17155"
                     /protein_end="445"
                     /protein_start="13"
                     /score="338.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="DEQSEKYPKREALVYADRDLRMTYEEFNRQSRLVARGLMALGIEK
                     GDHIAVWTTNVPEWVQLQFSTGKMGAPLVTVNTNYRASELEYLLKQSDSKTIILIENYR
                     DHSFINTLQELCPELEHCEPGNLQSKRLPLLKNVILIGDAKYPGVLNWSDVLAAAEQVK
                     EEQLDIRQGTLHYDDVINIQYTSGTTGFPKGVMLTHFNLVNNAVNIAECMKLTHEDRLC
                     IPVPFFHCFGCVLGTLAITTSGGTMVPVQEFSPEEVLRTVEKEKCTALHGVPTMFISEL
                     NLPNFSSFNLSTLRTGIMAGSNCPVEVMKAVIEKMGMRDITISYGQTESSPVITQTKAD
                     DPFNLKVETVGRALPNLEVKIVDPDTNEEVAPNEQGELCTRGYHVMKGYYNNPEETGLA
                     IDRDNWLHTGDLATKDEAGYIRVTGRLKDMIIR"
     CDS_motif       10229..10261
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AEA09_RS17155_0001"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="AEA09_RS17155"
                     /protein_end="87"
                     /protein_start="76"
                     /score="-3.2"
                     /tool="antismash"
                     /translation="FSTGKMGAPLV"
     CDS_motif       10583..10636
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AEA09_RS17155_0002"
                     /evalue="1.30E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="AEA09_RS17155"
                     /protein_end="212"
                     /protein_start="194"
                     /score="24.0"
                     /tool="antismash"
                     /translation="IQYTSGTTGFPKGVMLTH"
     CDS_motif       11162..11227
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_AEA09_RS17155_0003"
                     /evalue="8.30E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="AEA09_RS17155"
                     /protein_end="409"
                     /protein_start="387"
                     /score="18.2"
                     /tool="antismash"
                     /translation="QGELCTRGYHVMKGYYNNPEET"
     gene            11651..13009
                     /locus_tag="AEA09_RS17160"
                     /old_locus_tag="AEA09_17190"
     CDS             11651..13009
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225534.1"
                     /locus_tag="AEA09_RS17160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17190"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_053585174.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 1.2e-12,
                     bitscore: 42.5, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 4.3e-07, bitscore:
                     24.9, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 1.7e-09, bitscore:
                     32.3, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 2.4e-06, bitscore: 22.1,
                     seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKKVLIANRGEIARRIIRTCKRLNIQTIAVYSEADAEALHVRDA
                     DEAYCIGKPPVAHSYLNIERILEVAKESNADAIHPGYGLLSENANFAKRCAEVGLVFIG
                     PNADVIASMGSKLEARKTMKAAGVPIVEGVETPVKDAAEAVEIAARIGYPIMLKASAGG
                     GGIGMQLVENAEELTKAFEGNQRRAESFFGDGTMYMERFIANPHHVEVQIIADHHGNVV
                     PLFERECSIQRRNQKVVEEAPSPFISEETRKQMLDASVQAAEHIGYVNAGTIEYLVDAD
                     QNFYFLEMNTRLQVEHPVTEEITKLDLVEEQLKVAARQPLAFTRDTIEIQGHAIEVRIY
                     AENPTTFFPSPGKITELELPTGVGIRHECGVEAGSIVTPFYDPMISKLVVWGETRAIAC
                     ERLTQALTDYKIEGIQTNIPMLLKTVTHEQFLKGSTTTKFVEEYYLPQLEEMK"
     misc_feature    13332..13351
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 21.06"
                     /tool="antismash"
     gene            13577..13789
                     /locus_tag="AEA09_RS17170"
                     /old_locus_tag="AEA09_17200"
     CDS             13577..13789
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016992214.1"
                     /locus_tag="AEA09_RS17170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17200"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_053585176.1"
                     /transl_table=11
                     /translation="MEVVKASMAGTVWKIVVAEGDQVTAGQDVAILESMKMEIPIAAEE
                     GGVVTKIIANEGDFINLDDPILEIG"
     gene            13802..14719
                     /locus_tag="AEA09_RS17175"
                     /old_locus_tag="AEA09_17205"
     CDS             13802..14719
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012292662.1"
                     /locus_tag="AEA09_RS17175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17205"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_053585177.1"
                     /sec_met_domain="HMGL-like (E-value: 3e-50, bitscore:
                     166.0, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHLPKHVTLKEVGPRDGLQNEKVHMATADKVQLVDLLSQTGLNYI
                     EVTSFVHPKWIPQLADAVEVLQAIKREKDITYAALIPNLRGLERALQANIDEASVFMSA
                     SESHNQNNINKTVTETFPVLEEVVLGAKAAGKRVRGYISTVIGCPYEGYIQPEQVLRVA
                     DKLLEMDVAEISLGDTIGVGVPTQVERLLEELLKRYPAEKFAMHFHDTRGTALTNIVKS
                     LEMGITKFDSALGGLGGCPYAKGASGNVATEDLLYLFDEMGIHTGIEMNAVLEAATFVE
                     KKLGKPVASKQMAIVRNERSGQAL"
     gene            14716..15498
                     /locus_tag="AEA09_RS17180"
                     /old_locus_tag="AEA09_17210"
     CDS             14716..15498
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (11-252). E-value: 4.4e-66. Score:
                     214.6. Matches aSDomain:
                     nrpspksdomains_AEA09_RS17180_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012292663.1"
                     /locus_tag="AEA09_RS17180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17210"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_053585178.1"
                     /transl_table=11
                     /translation="MTQLVQFELLGDGVGIITLMRPEAANAMSVQLLTDLGDMLDQVNK
                     NPAVRVVLLTGAGEKAFCAGADLKERQGMSDRQVKQIVQLIGGTVAKVEALAQPVIAVL
                     NGVAFGGGLELALACDLRIAASHVKVGLTETSLGIIPGAGGTQRLPRLIGIGKAKELIY
                     TARRLNAVEAKSYGIVEYVYEGHELQEKAQQLALEIAKNAPLSLVQAKIAINQGVEVDL
                     ATGLKIESLAYSALIPTEDRLEGLLAFQEKRTPQYSGQ"
     aSDomain        14749..15471
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AEA09_RS17180_ECH.1"
                     /evalue="4.40E-66"
                     /label="AEA09_RS17180_ECH.1"
                     /locus_tag="AEA09_RS17180"
                     /protein_end="252"
                     /protein_start="11"
                     /score="214.6"
                     /tool="antismash"
                     /translation="DGVGIITLMRPEAANAMSVQLLTDLGDMLDQVNKNPAVRVVLLTG
                     AGEKAFCAGADLKERQGMSDRQVKQIVQLIGGTVAKVEALAQPVIAVLNGVAFGGGLEL
                     ALACDLRIAASHVKVGLTETSLGIIPGAGGTQRLPRLIGIGKAKELIYTARRLNAVEAK
                     SYGIVEYVYEGHELQEKAQQLALEIAKNAPLSLVQAKIAINQGVEVDLATGLKIESLAY
                     SALIPTEDRLEGLLAFQEK"
     gene            15797..17335
                     /locus_tag="AEA09_RS17185"
                     /old_locus_tag="AEA09_17215"
     CDS             15797..17335
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012292664.1"
                     /locus_tag="AEA09_RS17185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17215"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_053585179.1"
                     /transl_table=11
                     /translation="MSNVTTDNTANSMKEQILTGGQPKYHEKNTQQGKLFVRERLELLL
                     DDGLQSEDGLFANCLAGDLPADGVVTGIGKIHGRTVCIMANDSTIKAGSWGKRTVEKII
                     RIQETAEKLNCPLLYLVDSAGARITDQLEMFPGRRGAGRIFYNQVKLSGKVPQVCLLFG
                     PSAAGGAYIPAFCDIVVMVEGNASMYLGSPRMAEMVIGEKVDLETMGGAKMHCSVSGCG
                     DVLTKTEQEAIAYARKYLGYFPNNYAERSKVEAPKPPASFEKSIEELIPKNQNVPFDMY
                     QLIDRLIDEDSFCEVKKLFAPELITGLGRINGQSVGIIANQPRAKGGVLFHDSADKAAK
                     FISLCDAFNIPLIFLADVPGFMIGTQVEKAGIIRHGAKMIFAMSEATVPKLTVIVRKAY
                     GAGLYAMAGPAFEPDCCIALSNAQIAVMGPEAAVNAVYANKIAALPKEEQADFIAEKRK
                     EYQEEIDVYRLASELIIDDVIEPNDLRKALETRLELYMSKYVLFSQRKHGVNPV"
     gene            17465..18034
                     /locus_tag="AEA09_RS17190"
                     /old_locus_tag="AEA09_17220"
     CDS             17465..18034
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /GO_process="GO:0071555 - cell wall organization [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008176113.1"
                     /locus_tag="AEA09_RS17190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17220"
                     /product="VanZ family protein"
                     /protein_id="WP_053585180.1"
                     /transl_table=11
                     /translation="MAKNNIANVQDDTKLPLPYRVWIDKYYMEIKFTGWLLFSVYSCIA
                     FYKLVIDRLVNVVLVLFRGEYTLGELGLFDYSTWRGTTNFVPFDTIMRYINYSQYFNID
                     LIVVNLLGNLLIFTPMGFLLPLLSKRFRRVWPVILIGFLSSLAVETVQFIFRVGSTDID
                     DLILNTAGAFIGYVAYKCMLQFSKSK"
     gene            18277..19077
                     /locus_tag="AEA09_RS17195"
                     /old_locus_tag="AEA09_17225"
     CDS             18277..19077
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225526.1"
                     /locus_tag="AEA09_RS17195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17225"
                     /product="putative metalloprotease CJM1_0395 family
                     protein"
                     /protein_id="WP_053585181.1"
                     /transl_table=11
                     /translation="MKISGLIQQERIAALEDRRKILQRKGVGDVYRKNLQYFQPKKNPA
                     LIELENLLFGHKDHDLYEKHKEESKEVTHQEQATIREMQQTEKSVRAHEQAHKAVGGDV
                     TGPISYTHTTGPEGERYITGGEVSITAGAGSTEEETLQILEKVRSAALAPVDPSPQDLR
                     VAASAGEQIQQVQAKLNGTEIEETNDLDEEPAFVREPIEIKVPERFSKELKLDPFADTI
                     FGRSYEESYMANIFKHVAAKYTAHSEMAKNGYLPRYEPTFSWTA"
     gene            19101..19595
                     /gene="ybaK"
                     /locus_tag="AEA09_RS17200"
                     /old_locus_tag="AEA09_17230"
     CDS             19101..19595
                     /GO_function="GO:0002161 - aminoacyl-tRNA editing activity
                     [Evidence IEA]"
                     /GO_process="GO:0043039 - tRNA aminoacylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="ybaK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225525.1"
                     /locus_tag="AEA09_RS17200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17230"
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="WP_053585182.1"
                     /transl_table=11
                     /translation="MAKAKHVKTNAVRLLEQQKIQFDVMEYETGDGQVDGISVAEKIGH
                     PVSRVFKTLVAKASAQKLFVFVIPVAEELDLKAAAKVVGEKKIEMLPVKELLGYTGYVR
                     GGCSPIGMKKLYPTVIDESAREQGSIIVSAGKIGMQIHVQIDDLLAVTKGQLAPITTIH
                     D"
     misc_feature    complement(19717..19729)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            19724..20359
                     /locus_tag="AEA09_RS17205"
                     /old_locus_tag="AEA09_17235"
     CDS             19724..20359
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225524.1"
                     /locus_tag="AEA09_RS17205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17235"
                     /product="membrane protein"
                     /protein_id="WP_053585183.1"
                     /transl_table=11
                     /translation="MRRVIGWRWTFFIAGMLIMSLGITMSIKGKVIGTSPWDVLHVGLF
                     QNFGLTIGTWSILTGLLIITSTSLVLKEWPKLGTWLNMFLIGLFIDVFNWLLPATDVYV
                     LQIAYFVVGVFILSFGCGMYIAPNMGAGPRDTLMMILVEKFGGTIKSARMGIEVLVTIL
                     GGLLGGPVGIGTVLIALTSGYIVQYSLPYCRKVLLKCIGNMEGVKPFY"
     gene            20460..21536
                     /locus_tag="AEA09_RS17210"
                     /old_locus_tag="AEA09_17240"
     CDS             20460..21536
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009371628.1"
                     /locus_tag="AEA09_RS17210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17240"
                     /product="nucleotide kinase"
                     /protein_id="WP_053585184.1"
                     /transl_table=11
                     /translation="MNGNVTYYYGHALTGQGRKHLYKEMMDEAALVYILQGAPTYRGSE
                     LLKELGYFYVKQGFAVEWFKHALLEEIVEAVFIRECNYLFVWSSEWNLEPSLLGTKHRV
                     ISFYDCLEEKQLEGVGGQLATAMRDRELWREKCICMLEIAKKLHDDWEVVTQSCMDWQA
                     LDDQITSLKTDLFQSMTLNKTGIRTHRLLGTLTPTGAQNTVESMTKNLKRRLMIKGKPG
                     TGKSSLMKSLADEANTRGLDAQIVWCGLDAGSVDMIIIPELNFCIFDSTDPHIFDPEEG
                     RSGDAIFDMGQHCKLTEEAEAEIEDIRAAYKESMQNAMGYAVRYAEVEHTIRQLMDRCL
                     STSAWREKTAPLFQRLRK"
     gene            21605..22795
                     /locus_tag="AEA09_RS17215"
                     /old_locus_tag="AEA09_17245"
     CDS             21605..22795
                     /EC_number="2.3.1.29"
                     /GO_function="GO:0008890 - glycine C-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (41-382). E-value:
                     1.3e-67. Score: 220.4. Matches aSDomain:
                     nrpspksdomains_AEA09_RS17215_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1109: 8-amino-7-oxononanoate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008404622.1"
                     /locus_tag="AEA09_RS17215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17245"
                     /product="glycine C-acetyltransferase"
                     /protein_id="WP_053585185.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 9.7e-67, bitscore:
                     220.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKILNAFLDENLQALREQGLYNEIDPVESANGPVIQVRGKQLIN
                     LSSNNYLGLATNDELKRIAKEATDKYGVGAGAVRTINGTLDLHVKLEEKLAEFKGTEAA
                     ISYQSGFNCNMAAISAVMDKNDAILSDQLNHASIIDGCRLSRAKIIAYNHSDMDDLRAK
                     AKDATESGLYNKVMVITDGVFSMDGDIAKLPEIVEIAKEFDLITYVDDAHGSGVTGKGK
                     GTVKHFGLEKEIDFQIGTLSKAIGVVGGYVAGKKNLIDWLKVRSRPFLFSTALPPGDVA
                     AITAAVQMLIDSTELHDKLWDNGDYLKAGLAKLGFNIGNSETPITPCIIGGEKLTQEFS
                     RRLFEEGVYAKSIVFPTVPAGTGRVRNMPTAAHTKEMLDNALAIYEKVGRELGIIQ"
     aSDomain        21728..22750
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_AEA09_RS17215_Aminotran_1_2.1"
                     /evalue="1.30E-67"
                     /label="AEA09_RS17215_Aminotran_1_2.1"
                     /locus_tag="AEA09_RS17215"
                     /protein_end="382"
                     /protein_start="41"
                     /score="220.4"
                     /tool="antismash"
                     /translation="QLINLSSNNYLGLATNDELKRIAKEATDKYGVGAGAVRTINGTLD
                     LHVKLEEKLAEFKGTEAAISYQSGFNCNMAAISAVMDKNDAILSDQLNHASIIDGCRLS
                     RAKIIAYNHSDMDDLRAKAKDATESGLYNKVMVITDGVFSMDGDIAKLPEIVEIAKEFD
                     LITYVDDAHGSGVTGKGKGTVKHFGLEKEIDFQIGTLSKAIGVVGGYVAGKKNLIDWLK
                     VRSRPFLFSTALPPGDVAAITAAVQMLIDSTELHDKLWDNGDYLKAGLAKLGFNIGNSE
                     TPITPCIIGGEKLTQEFSRRLFEEGVYAKSIVFPTVPAGTGRVRNMPTAAHTKEMLDNA
                     L"
     gene            complement(22942..24075)
                     /locus_tag="AEA09_RS17220"
                     /old_locus_tag="AEA09_17250"
     CDS             complement(22942..24075)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010284758.1"
                     /locus_tag="AEA09_RS17220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="AEA09_17250"
                     /product="alpha-hydroxy acid oxidase"
                     /protein_id="WP_053585186.1"
                     /transl_table=11
                     /translation="MTNSDLLLQNIKAEKPFPIAFSDLEKAAKEKLEVGPFGYIQSGAG
                     NEQTLRNNRTAFEKYSITPRFLRDVSQLDTSISLFGKTFPTPLLFAPVGMNGMEHPDGE
                     PAVAKAAEKLSIPYIQSTVSTYSMEDVAKAAPNSTRLFQLYWSKNEDISYSMVERAEKA
                     GFSAIVLTIDTVMLGWRTEDVRNQFSPLKLGFAKGNYMQDPVFTEALPDDSFDSYVASV
                     IDNIYHPHMTWEHVAELKMRTTLPIYLKGILHPDDAQLALENGIDGIIVSNHGGRQLDG
                     VIGSLDALPSIVEVVAGRVPVILDSGVYSGIDVLKALALGADAVAIGRPFVYGLALAGQ
                     AGVEQVMQNIYEEFKVSLALAGASSIAEARKLQLVKA"
     misc_feature    complement(24334..24348)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.5"
                     /tool="antismash"
     misc_feature    24436..24454
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: medium, score: 25.13"
                     /tool="antismash"
ORIGIN
        1 tgtggggcgt gtgtttgtgg tagccaagca gaaaccatac catcaacttc gcccttagaa
       61 attgcttccc acataatacc attgtcaagt ggtgttagtg tgacatcata tcctaaatcc
      121 tcaagtactt gtccaattac atgtgtagaa gcaatttcag tatcccattc cacataggtt
      181 aggttgactt ctttattttt tgtgtcttca tcacctgagc cacaagcaac taataataaa
      241 cttaatccta aagccaatcc taacttagat aatctaccaa atctcatgaa atctcccttt
      301 ctaactgtag tctttaattt tattaagtga tttataacca taaattagta agtaacaacc
      361 taatattaaa ggtaagttgt tacttttgtc aaatagccaa tgaaaatgga aggtttggag
      421 ttttaaggag taggtacagt gattgtaaaa gtttgattaa tcattaaaga gtaactttct
      481 tgtgaaaagg ggaagaataa tcaactctct tatatctgaa cgtatcaaaa aagaggtact
      541 gtggaaaact acatttaaac aagataaaaa tgaggtcaag tggtttttta gttggcaatt
      601 taagtattac ttgtatagag agtaataagt tagcatgccg cttcaaattg ttagatcgaa
      661 tatagacttt ttctacatac taaatttacc gaccgggtat aagtgattca caacactcaa
      721 taattttgtg aatttttttt gtgaagctgt atacattctg cctactcatt cgttaaaaag
      781 gtgaaggcaa tgaaaacatg aaagtgagaa gggtagcggt gacagatgat ttaattacat
      841 cactatataa agaaaaagca gttattatca aaaaatattt aataaagaat ggatgtagtt
      901 tgttagatgc tgaagatatc gtacaaggaa catttgtaaa ggcaattcaa tatatggtag
      961 agcttcatga aaaaaatctt tcagcctggc tgtttaaggt agcgctgcat gcttactatg
     1021 atttatgtag aaaaaacaat cgatttccaa gctgctcttt agaagatcaa aatcaatttt
     1081 tcactggatt agcagatgaa cttgatggag aaaagttgct tttatccaaa gaaaaagctg
     1141 aagaaataac acaagtcgtt aatatgctaa accctaatca acgaaatctt ttgctactaa
     1201 aatatgaaat ggaactctca tataaagaaa tcgcagaact tacggatatg gatgaaaaaa
     1261 cgattaaaac ctatttgtat agggctcgtt tagctttcaa aaagaaatgg gaggagacga
     1321 ataatgaaaa aatcaaagat agatgattta tttgatttcg aaaatgtcga tacagaaaaa
     1381 atgctaaaag aagcaaaagg gaaaagctac gctcgaataa tcttaattag tttaagtatg
     1441 gcaatttata tttttggatt aatttattta gaaaagatac aaatcacacc ttttctactt
     1501 gataataaaa tttcagaaat agattcttat tacagtgtgt atggagcgaa tactcaccta
     1561 ggaatatggg atgaagagta tcgtttcatt ggtagtagtg caacagctcc aaaatataaa
     1621 attattgatg gaaaaccagt aagcttagga gaggtaaaag taccatggaa agtaaacttt
     1681 aatgaattct cgctaaattc taactggcca acaacagaca cgaaagatgt atttacgtac
     1741 gatggagtta gaaagctaca attctatcat ccatctgtaa cttacgagga atataaaaac
     1801 gatttaagtt taatagcaga aattcctgat tttaaaaaaa tagagatggg aatctctttt
     1861 gacaagccat acacattaca agaagttcaa aatatgctac caaaaaacgt gaaatttcaa
     1921 tgggcatggg tagatattta tgatgaaacg tacttacaag gattgaaatc atcagatgga
     1981 acgccttcag tagttgtatc cgaagagtat gccgcgggat ttcatttata tgatcaagta
     2041 ggagaggcaa tcaaaaaccc gaaagaaaaa tttgttgaaa acttagaact agctttaagg
     2101 aataaaagcg attactataa cgatttaaaa acaatagacg attttctaaa acaagaaaat
     2161 gaagcaatca acaccgataa tatcatgatt gttggcgctg ttattacagg cagtccaaaa
     2221 gatattttaa gtgtacaaca taaagaatac gtaaaagcgg ctgttttagg agccgttgta
     2281 gataagtatt aaaggagtga agaatggtga aggtttttat ggaaaataga ccgattctat
     2341 ttggcggttt agcatttgga ctagcctctc ttgtgctaaa ttgtttgtat attatttttt
     2401 tcaacatggc tcatgtttat gatgtgatac atgttatccc aataattttt ttgatggatc
     2461 ctattgtaga aaaaatagga tatatggcta ctccgtttat gcttctacca atagctatta
     2521 ttctagattt tatttgtggc ttgcttttcg ggtggattgc gaagaaactt acaaaaacac
     2581 tactcgctta cgtagtagct ctattacttt tatttggctt ctactgggtc gtgattacgt
     2641 atcaatggat tttgatttta taagtagata aagctaaagg tactttaaat ttaacttcaa
     2701 taatttcgta gctccaaaca acgtgtaaaa tatttatttc ctgttcattg attagtaaaa
     2761 tggacaggtt ttttatttta tccaattcgc aacagcatat gaaaaaacgt taaaaaaata
     2821 agtattgaaa gatacttcga ttaggctatt tacgatacga cttatctaaa aataagtgaa
     2881 aaagagtaac atagacaggg ggaagtgaag tttatttatg aaagcacatt gaaaaaatat
     2941 gatactaaag atgcaccatg cattttcaat gtggcattaa acattttatt gagacgatgc
     3001 cggtacaaaa gcgtgcctat tatgaaagtt agtgcgtaaa ctagaatgaa ttcaaaaaaa
     3061 gctttatctt cattcagaag attccctcca ctatagattg tgagtggaat gggagtttag
     3121 ttttttcagt gggtatctaa acgctgactg aaagaagata aagcctccag ccgatgtcac
     3181 agatgttttt tgcgcgaaag cgaagcgtca gcagcagatt tttagggagt caatttagga
     3241 agttagccta aggtcgtagc atccatgcga caacggctaa cagacctaca tcgtgtaggc
     3301 ctaagcacaa ttcaaaatct agacgcattg tttttctatg cgaaagcgaa gcgtcagcaa
     3361 cagtcgcatt gttttcctgt gcgaaagcga agcgtcagca acaggtacaa ttacgctgag
     3421 tcgtaattga ttgaataatg atggggttga ctagaatgaa cgaggattta caaagattac
     3481 aaccgaagtt agttgagatt tttaaacatt tacatgaaca tcccgaaatt agttggcaag
     3541 aacagcaaac gacgaaatac attgcaaata tattgaaaga tgcagatatg gaaccacatg
     3601 tgttcgaaga tatccctgga ctttatgtcg atatcggaaa aggaacacca aaagttgggt
     3661 ttcgaacaga tatggatgcg ctctggcaag atgtagatgg ggtttttaag gcgaatcatt
     3721 cttgtggaca tgatggtcat atgacgatgg ctattgggac ggcattactt ttaaaagaga
     3781 tggagtccgt tctttctggt gcagtacgga ttatttttca gcccgctgag gaaaaagcgg
     3841 agggtgccca tgccttagtc caaaaaggtc ttatagatga tctagattat ttattcggcg
     3901 tacacgttcg tccactaaaa gaattgccgg atggcacaca tgcaccagca atttatcatg
     3961 gagcagccaa gatttttaca ggaacgatta ttggtgaaga tgcacatgga tcacgtcctg
     4021 aacatggcat taatgctatt gaggtaggcg cagcaatagt tgaaggttta caaaaaattt
     4081 ggacggattc gaatgtatcg gcatcagcca aaatgacgca attccaagca ggaggttcct
     4141 cagcgaatat tatccctgga aaagcgacat ttagtattga tgcacgtgct caaacgaatg
     4201 aagcgatgct ttcattaact aaaggtattg agcgtgtgaa aacttcagtg gaaatacttt
     4261 atggtgcaat gatagattta cgagcagatg tacacgttgt tgctgcttta gtaaatgagg
     4321 atgcagtgga aattatgcga acggctatta ttgaggttgt tggtgaggaa gcatgtgcac
     4381 cgccagttgt tacgccaggc gctgaagatt ttcattttta tacgtatgaa cggcctaacc
     4441 tgaaagcgac gatgcttgga tttggatgtg gtgtaacacc aggattacat catccaaaaa
     4501 tgacatttaa tagagaacga cttatgacgg gtgtaagtat tattacacga gccattttgc
     4561 gtgcgttata aagacgagaa agtaaactta gagatttccc ctttaatgta atgaatgata
     4621 ttaaggggat tttttgtctt tacaccaaaa gctgttcatg caaaatattt gcatgaattc
     4681 tgagcatgtc caaatcgtga ggtcacattc atttttctta cgagcgaaaa ctgaacaaca
     4741 aattctttta gaatattttt caaacgctaa aaagcctatt tgtcgaaatt gatatacgac
     4801 atattaaaaa atatgtgata aatagatgct aaagacctaa aatgacactt attaaaaaat
     4861 aagttgtata tcaaaatcga gcgtttgaat taattcgaga ttgtttaagt cagtgttaga
     4921 attcaactgt gtcaaaacga aatgaactcg ataaaatttt gagagaaaat gtggcttgag
     4981 cgtcctccta gcaactaccg cttcctcttt cgtcgcaaaa aaaagtttcg ctgcgttttg
     5041 tgcggggtct gaaggctcac acgcttttct tgctggatgt agcgaaaggc gaatgctatc
     5101 agctacactt gttaccctcc gttccatgtg cttataaaaa agcaaacttt cttttaaagt
     5161 aaagtccagg ttttgttaat gatccaaata attaatgatc taaattcgga aatattatta
     5221 tttttgctgc tctaattcta taaaatgcat ttttctgatt gaaatcagca tttttatagt
     5281 ctgttttatc agaaagaaca taagtctatt gccctatctg tgttaatttg tagagtggtc
     5341 agcggagaga aaatggctct gtttttagtt gttattgtac tttttttggt gtttttgtaa
     5401 gtataagtgc aatattattt ggcgcatacc tatgaatgaa actattttag tagaatgaca
     5461 tagggtgcct cttgattgga aaaaaagagt gaagtacata ttttagtgta atgccaatct
     5521 tttttatata agtttttatt gggtattgaa gggaaaaagg ggacccaaca ctaataagta
     5581 acagatagag tggaatggag ttggtgagaa tggaattaag agatttaaac atatttatgg
     5641 caattgtgaa gcatggaagt tatacgaagg cgtcggaagt gttatttatt tcgcaaccta
     5701 cattaagtaa aagtgtgaag cgtcttgaaa atgagttgca ggcgcaatta ctgcagcgaa
     5761 cgacaaggca gttacaagtt acagatattg gctcagttgt atacgaacat ggacaaaaaa
     5821 ttttatataa tctgcaggaa ttaggtcagt caatccaaga tatacgagat gtgcaattag
     5881 ggacgattaa gttaggcatt ccaccattga ttggcacatt gtttttccct gaaattgcgc
     5941 gtacctttca tcaacaatat ccaaaagtaa cattagaact cgtggagcgc ggggctaagt
     6001 taattagtga attagtacat tctgggcaag tggatgttgc ctttgtggta ttgccgattg
     6061 aggagcctgc gtttacgatc gagcagttta ttgaagatga ttttgtttta tatgtacata
     6121 aagagcatcc tttagcgcag tgtgcagaag tgtctgtaga agaattaaaa aacgaaaaat
     6181 ttattttatt ttccaatgag tatgccttac atgattttgt tattcgtgca tgtgaaaatg
     6241 ggggtttttc acctgacatt gtttataaaa gttcgcagtg ggatttaatt gtggaattga
     6301 ttgggctcaa tttagggctc acgattttgc ctagagcaat ttacgagaag cagtcaaatc
     6361 ccaatgtgaa aattattccg ctgaccaatt cacttatttg gaagttaggc ttagtcagtt
     6421 taaaagatcg ttacaaatcc tttgccctac aggaattagt gaaaatgatt cgaacagaat
     6481 cgtggtcttg gcagtcattt attccattaa agaatgaata acatgctata tatgtatttt
     6541 tattatggaa ataaatggac taacattata gtacatataa gtataagggg tgatagggat
     6601 gacaaaagta aaacgatcat ttgaagaagc gcttgtagat ttaaaagatg gacaaaccgt
     6661 gattgtgggt ggttttggac tatgtgggat tcctgaaaaa gcgattgagg caatccgtca
     6721 aaaaggtacg aaggatttaa ctgtggtcag taataactgt ggggttgatg attttggcct
     6781 tggactttta ttagcgaaca agcaaattaa gaaaatggtg gcatcttatg taggtgaaaa
     6841 taaaatattt gagcagcaat ttttgagtgg ggagcttgaa gtggagttaa cgcctcaagg
     6901 tacattggca gagcgtattc gtgcgggtgg tgcagggatt ccagcctttt atacagcaac
     6961 tggcgtagga acaccaattg cagaggggaa gcctacgaag gagtttgacg gcaaagtgta
     7021 tttagaagaa cgagcaattg ttggcgacta tgcatttgta aaggcatgga aggcggatac
     7081 acttggcaat ttagtgtacc gtaaaacagc acgcaatttt aatccacttg cagcaacagc
     7141 tgggaaaatt acgattgctg aagtagagga aattgtggaa gtcggcgcat taaatcctga
     7201 tgaaattcat acacctggtg tatatgtgca acatgtttta gtgggcgaaa actacgaaaa
     7261 gcggattgaa cgactattga ctgctaagga ggttggatga ctatgtctga aacaagagat
     7321 cgtatagtac gtcgtgctgt gcaagaaatc gaaaatggca tgaacgttaa tttgggtatc
     7381 gggatgccga cattagtagc aaacgaaatt cctgcggatt atcaagtgtt attacaatct
     7441 gaaaatggtc ttttaggcat tggcccgtat ccgacagaag cggaagtaga tgctgattta
     7501 atcaatgcgg gtaaagaaac agtaacagcc gtggcaggtg cttcttattt tgatagtgcg
     7561 gaatcgtttg caatgattcg tgggggccat atcgatttag cgattttagg tggcatggaa
     7621 gtttcagaga ctggtgattt agctaactgg atgatcccag gaaagatgat taaaggcatg
     7681 ggtggtgcaa tggatcttgt acaaggagca aagcgtgtca ttgtcattat ggatcatatg
     7741 tctaaacatg gggagtccaa ggtaaaaaaa gaatgcacac tgccgttaac aggacagggt
     7801 gtaattcatc gtttgattac ggacttagcg gtatttgatt ttacaccgag tggaatggtg
     7861 ttagtagaaa aaatagctga tttatctgtg gaagaaattc gtgctcgaac ggaagcatcg
     7921 tttactgtaa gtgatggttt gaaagtgtat tgataaaaat tctgcttaat gaagtttata
     7981 tgctcgaaac gacatgaatc gacttaatta tcactggaca tccatttttt agaatgctat
     8041 attgaatttg tcttaatatt ttgctagata ggtaaaatga gtagtgaagt tcagagtaac
     8101 aaatgaggga tagatgctta tggtgaagaa aacgttaaaa caacggattg tagaggcttc
     8161 cctaatactg tttcagcaag atggttatca tggcgtgaca gtcgatcgta ttgtcgaata
     8221 tattggtgca tcaaaaggtg gattttatca taatttcaaa tcaaaagatg agttgttata
     8281 tgaaattcat gatgtcttca tttcttatgt tatcaaaaaa tcacaagatg cctatgatca
     8341 atacaataca ccaatcacca gattatgcgc gatgatccaa acacttaccg aagtgtttga
     8401 cgtgtatcag gcacatatca cggtttttta cgaagaaagc ggttcgttgc cagaagtgta
     8461 cagtgaactt atacacaaaa aacgcaatca gtatcgtgga attttacaga aggtcattgt
     8521 tgaagggcag cagacaaatg attttcgttc agaattaccg ggtacgattg tgacgatggc
     8581 aatcgtgggc atgattaact ggacatataa atggtataag caaacagggc cactgacaat
     8641 ggaagaaatt acagtagtat ttatggacat gattttacat tcaattgtga ccgaacaagc
     8701 tagggaagaa gcaactcaat ttatgatcgc aatgaagcca gctacagaga ctggttttat
     8761 taattagtaa tacaaaccga ctagtcggtt taactttttt agcagatgca aagggggagc
     8821 tagggatgaa ctttgaacta acgaaagagc aagagatgat tcgggatatg gttcgtgatt
     8881 ttgcagagaa ggaaattaag ccatatgcac gtgaagtgga tgaaacttca acaatgcgaa
     8941 tagaaagctt tgaaaaaatg gctgaactcg gtttgatggg tatcccattt ccagaagagt
     9001 acggtggttc gggtggagac acagtttctt atgcgattgc tgttgaagaa attggccgcg
     9061 cctgcggggg tacaggttta agctatgcag ctgcgattag tttaggtgct gcacccattt
     9121 ataattttgg gacagaagag caaaaacgtg aatggctggt tcctttagca aagggtgaga
     9181 cgctcggttc attcggttta accgaaccca atgcagggtc agatgcaggt ggaacgctta
     9241 caacagcagt tgtggatggc gatgattacg tgattaacgg cgaaaaatgc tggataacga
     9301 atgcgggtca tgcgcgtcaa atcatcgtca cagctgtaac gggtaaacgt gaagatggta
     9361 aaaaaattat ttcatcgatt atcgtgccaa ccaatacacc tggtgtcaca attaactgta
     9421 attatgacaa gatgggtgtg cgtggatcta atacgtgtga gattgtattg caaaatgtac
     9481 gtgtaccaag agctaatttg ctaggtgatg aaaagcgggg cttcagtcaa tttttaaata
     9541 ctttagatgg tggacgaatt tccattgcgg cattatcagt agggattgca caagcagctt
     9601 acgagaaggc gctacaattt gcaaaagagc gtaaacaatt cggcgtatcc atttcaaaat
     9661 tccaagcaat acaatttaaa ttagccgata tggcaatgga aatagagctt gctcgtacgt
     9721 tagtacataa agcggcatgg cttaaagacc agaagaaacc gtttggtaaa gaagcggcga
     9781 tggcaaaatt atttgcctcc gaaatgggct tccgtacttg caatcaagca attcagattc
     9841 atggtggttc aggttatatg aaggaatatg atgtagagcg tcatttgcgt gacattaagt
     9901 taatggaaat tggtgaaggt acttctgaaa ttcaacgtct cgttatttct cgtttaattg
     9961 gctgttaaaa aattcaatag caaatacaag gaggattttc atggcagagc ttgtatatca
    10021 aacaattggt cagttgctag atgaacaaag tgaaaagtat ccgaaacgtg aagcgcttgt
    10081 gtatgcagat agagacttac gaatgactta tgaggagttt aatagacaga gccgcttagt
    10141 tgctagaggt ttgatggccc ttgggattga aaaaggcgat catattgctg tgtggacgac
    10201 gaatgttcct gagtgggtgc aattacagtt cagtacaggg aaaatgggcg ctccccttgt
    10261 aacggtaaac acaaattacc gagcgagtga attggaatat ttacttaaac agtctgattc
    10321 aaaaaccatt attttaatcg aaaactatcg agatcattct ttcataaata cactacaaga
    10381 attgtgtcct gaacttgagc attgcgaacc tggaaattta cagtctaagc gtttaccttt
    10441 attgaagaat gttattttaa taggcgatgc gaaatatcca ggggtgttaa attggtcgga
    10501 cgtattagct gccgctgagc aagtgaagga agagcagtta gatatcagac aaggaacttt
    10561 gcattatgat gatgtcatta atatacaata tacatctgga acgactggtt ttccaaaggg
    10621 tgttatgtta acgcatttta acctagttaa taatgcggtc aacattgcag aatgcatgaa
    10681 attaacgcat gaggatcgtt tgtgtattcc cgttccattt ttccactgtt ttggctgtgt
    10741 ccttggtacg ttggccatta caacaagtgg aggcacgatg gtacctgtac aagagttttc
    10801 gccggaagaa gtattgcgaa cggtagaaaa ggaaaagtgt acagcattac atggtgtgcc
    10861 gactatgttt attagcgaat tgaatttacc gaatttttcg tcatttaatt tatcaacgct
    10921 acgtactgga ataatggcag gctcaaactg cccggtcgaa gtgatgaaag ctgttatcga
    10981 aaaaatgggc atgagagata taacaatatc ttatggacaa acagagtctt cgccagttat
    11041 tacgcaaacg aaagcagatg atccattcaa tttaaaggtc gagacagtcg gccgtgcatt
    11101 accaaactta gaagtgaaaa ttgtggatcc tgatacaaat gaggaagtgg caccaaatga
    11161 gcaaggggag ctatgtacaa gaggctacca cgtgatgaaa gggtattaca ataatccaga
    11221 ggaaaccggt ctggctattg atcgtgataa ctggcttcat acgggggatt tagcgacaaa
    11281 ggatgaagca ggttatatac gcgtgacggg tcgtttaaaa gacatgatta ttcgcggtgg
    11341 agaaaatctc tatcctcgtg aaattgaaga gtttctttat acacatccga aaattttcga
    11401 tgtgcaagtt gcgggtgtac ctgatccagt ttacggagaa gaagtggcgg cttggattat
    11461 tttacgtgaa ggcgagcagg caacagctga agatattcga gacttttgcc gaaataaaat
    11521 ttcaaaacaa aaaataccaa aacatatttt ctttatcgat agctatccaa tgacagcttc
    11581 gggtaaagtg caaaagttta aattacgtga tgaatttgtt atagcagtga ggtagggagg
    11641 gggcagggaa atgttcaaga aggttttaat tgcaaaccgt ggtgaaatag cgaggcgtat
    11701 tatcagaaca tgtaaacgat taaatatcca aacgatcgca gtgtactcgg aggcagatgc
    11761 tgaggcgcta catgtaagag acgcagacga agcctactgt attggtaagc cacctgtagc
    11821 gcacagctat ttaaatatcg agcgtattct tgaagttgcg aaggaaagca atgcagatgc
    11881 aatccatcca ggctatggct tgttatcgga aaatgcgaat tttgctaaac gttgtgcgga
    11941 ggtaggtctt gtctttattg gaccaaatgc tgatgtgatt gcgtcgatgg gcagtaaatt
    12001 agaagcgcgt aagacgatga aagcagcggg agtaccaatt gtggaaggtg tggaaacgcc
    12061 ggtgaaggat gcagccgaag ctgtagaaat tgcagcacgc attggctatc caattatgtt
    12121 gaaagcatca gctggtggcg gtggtattgg tatgcaactt gtagaaaatg ccgaggagtt
    12181 gacgaaagcc tttgaaggca atcaaagacg tgcggagtct ttcttcggtg atggcacgat
    12241 gtacatggag cgatttatcg ccaatccgca ccatgtagaa gtgcaaatca ttgctgatca
    12301 tcacggaaat gttgttccat tatttgaacg cgagtgctcg atacaaaggc gtaatcaaaa
    12361 agtagtcgag gaggcgccat ccccgtttat ctcagaggaa acaagaaagc agatgctaga
    12421 tgcttctgtg caagcagccg aacatatcgg ttatgtgaat gcaggcacaa ttgagtattt
    12481 agtagatgca gaccaaaatt tttatttctt agagatgaat acgcgcttac aagtcgaaca
    12541 tccggtgacg gaagagatta cgaagctaga tcttgtagaa gaacaattga aggtagcggc
    12601 aagacagcca ctagcgttta cacgtgacac gattgaaata caaggacatg cgattgaagt
    12661 gcgaatttac gcagaaaacc cgacgacgtt tttcccgtcc cctggcaaga tcacagagct
    12721 agagctaccg acgggtgttg gtattcgcca tgaatgtggt gtagaagcag gctcaattgt
    12781 aacaccattt tatgatccaa tgattagtaa attggtggtg tggggcgaaa cacgtgcgat
    12841 tgcatgcgag cgtcttacac aagctttaac agattacaaa atagaaggta ttcaaacaaa
    12901 catccctatg cttttgaaaa ctgtaaccca tgagcagttt ttaaaaggct ctacaacgac
    12961 taagttcgtt gaggagtact atttacccca actagaagaa atgaagtaaa catggaggag
    13021 tattgcaaag atttgttgca atacctccac atttttgaaa aacaataacg acaataaatg
    13081 ctttatgaac gtttatgaga gtttgttcaa gggacccgtt gatttccgtt ccaggcggac
    13141 gcgttccagg gggcgagcct tgagccgctt cgtcgcttac gctcctgcag ggtctcaagt
    13201 tgctcgctga tcccctagga gtcgccgcct ttcactccaa tcaactagaa ttttcttgga
    13261 tcatcaccaa aagccggaga tgacattttg aataaagtgt ttgttgattg gagtgaagcc
    13321 agcgtgactc cttggggact agcgtcacag ataagaccct ggagcgagca tagcgagtga
    13381 agcggcttat cggacgcccc caggaaagca cgctggcgca acggaaatca atcccatgtt
    13441 ttggtataga gaccattttt aagaacaatt tttttcgcgc tatttctatg gataaaatac
    13501 tttatcaacg gaatggaagt attgcgatgt cttgttgcaa tacttcctta ctatcaacta
    13561 tttggaggga tttatgatgg aagttgtaaa agcgagcatg gcaggaactg tttggaaaat
    13621 tgtcgtagca gagggcgatc aagtaacggc agggcaagat gttgccattt tagaatcaat
    13681 gaagatggaa attccgattg cagcggaaga aggtggcgtt gtcacaaaaa ttattgccaa
    13741 tgaaggtgat ttcattaact tagatgatcc aattttagaa atcggataag ggggcacagt
    13801 tatgcaccta ccaaaacatg tgacgttaaa ggaagttggc cctcgggatg gtctacaaaa
    13861 tgaaaaggta cacatggcta ctgccgataa agtacagctt gtggatttac tcagtcagac
    13921 gggactaaat tatattgaag taacgtcttt tgtacatcca aaatggattc cacaactggc
    13981 agatgcagtg gaggtgttgc aagccattaa gcgtgaaaaa gatattacgt atgcagcact
    14041 cataccaaat ttgcgtggct tagaacgtgc gttacaggca aatatagatg aagccagtgt
    14101 cttcatgtca gcaagtgaaa gccataatca aaataatatt aataaaacgg taactgagac
    14161 atttcctgtg ttagaggaag tcgttttagg ggcaaaggca gctggaaagc gagtacgtgg
    14221 ctatatttca acagtgattg gttgcccata tgaaggctac atacagccgg agcaagtttt
    14281 acgtgtagca gacaaattac ttgaaatgga tgttgctgaa atttcgttag gcgacacgat
    14341 tggcgttggc gttccgacac aagtagagcg tctattagaa gaattgttaa aacgatatcc
    14401 ggcagaaaaa tttgcgatgc attttcacga tacgcgtggt acagcgctta cgaatatagt
    14461 aaagtcccta gaaatgggga ttacaaaatt cgatagtgcg cttggtggac tcggtgggtg
    14521 tccttatgca aaaggagcat ctggcaatgt ggccacagag gatttattgt atctatttga
    14581 tgaaatgggt attcatacgg gtattgaaat gaatgcagtg ctagaagcgg cgacatttgt
    14641 tgagaaaaaa cttggtaaac cagttgcatc aaaacaaatg gcaattgtcc gcaacgaaag
    14701 gagtgggcag gcactatgac acaacttgtt cagtttgaat tactaggtga tggtgtaggg
    14761 atcataacat tgatgagacc tgaagcggca aacgccatgt ctgtacagct cttaacagat
    14821 ctaggtgata tgctcgatca agtaaataaa aatccagcgg tacgtgtcgt gttactaaca
    14881 ggagctggag aaaaggcctt ttgtgcaggc gcagatttaa aagagcgtca aggcatgtct
    14941 gaccgacaag tgaagcagat tgtgcaatta atcggtggga cagtggctaa agtagaagcg
    15001 ctcgcacaac cagtgattgc ggtactaaac ggcgtcgcat ttggcggtgg gctagagcta
    15061 gcacttgctt gtgatttacg tattgccgca tcacatgtaa aagtaggtct tacggaaaca
    15121 tcgcttggta ttattccagg agcaggtgga actcagcgtt taccacgact tattggtatc
    15181 ggaaaagcaa aggaattaat ctatacagca cgacgtttaa atgcggtaga agcgaaaagt
    15241 tatggaattg tagagtacgt atatgaaggt catgaacttc aagaaaaagc ccaacaactt
    15301 gcactggaaa tagcaaaaaa tgcaccttta tctttagtgc aagcgaaaat cgccattaat
    15361 caaggggtgg aagtcgattt agcaacgggt ttgaaaattg aatcactggc atatagtgca
    15421 cttattccaa cagaagatcg tttggaagga ttgctcgctt tccaagaaaa gcgaacgccg
    15481 caatattcag gacagtaaat taatttaatt cagtggtagt tcattatcta tttagatagt
    15541 gaaatgaaat atcaggttca gtgttgattc agtaggcatt caaacaccta ctgaattaaa
    15601 ttaaagcctc cggcggatgt catggatttt gaaaggagtt aattgtgcga gcacaattca
    15661 aaatccggac gcattgttta tctgcgcgaa agcgaagtgt aacgaagcgt cagcggcaga
    15721 tgttttttgt accgaaagca tagcggcagg tacaattgcg ccgaggcgta ttgattggaa
    15781 taaggaggaa tggaacatga gcaatgtaac gacagataat acggcgaatt cgatgaagga
    15841 acaaatttta actgggggtc agccaaaata tcacgagaaa aatacccaac aaggaaaatt
    15901 atttgtacgt gagcgcctcg aattattatt agatgatgga ttacaatcag aggatggctt
    15961 atttgcaaac tgtttagcgg gtgatttgcc agcagacggt gttgtcacag ggattggcaa
    16021 aatccatggt cgtacagtat gtattatggc gaatgattca acgattaaag ctggttcttg
    16081 gggaaaacgc acagtagaaa aaattattcg tattcaagaa acggctgaaa agttaaattg
    16141 tccgttattg tatttagtcg attcagcggg cgcacgtatt acggatcagt tagaaatgtt
    16201 cccaggacgc cgcggtgcag gacgtatttt ctacaatcaa gtaaaacttt caggaaaagt
    16261 accgcaagtt tgcttattgt ttggtccttc tgcagcaggt ggcgcttaca ttccagcatt
    16321 ttgcgatatc gttgtaatgg tggaaggcaa tgcatcgatg tacttgggct caccacgtat
    16381 ggcggaaatg gttattggtg aaaaagtaga tttagaaaca atgggcggtg ctaaaatgca
    16441 ttgctcggta tctggttgtg gtgatgtgct tacaaaaaca gagcaagaag ctattgcata
    16501 tgcacgcaaa tatttgggct acttcccgaa taattacgct gagcgcagta aagtagaggc
    16561 gccgaagcca ccagcatcct ttgaaaagtc aatagaagaa ttaattccaa aaaatcaaaa
    16621 tgtgcctttt gatatgtacc aattaattga tcgattaatc gacgaagatt cgttttgcga
    16681 agtgaagaag ttattcgcac cagaattaat cacagggcta gggcgcatta atgggcaatc
    16741 ggttgggatt attgccaatc aacctcgtgc aaaaggtggg gtattattcc acgattccgc
    16801 ggataaagca gcgaaattca tttcattgtg tgatgcgttt aatattccgc ttattttctt
    16861 agcagacgta cccggcttta tgattgggac gcaagtcgag aaagctggta ttatccgtca
    16921 tggcgcgaag atgatttttg caatgagcga agcgactgta ccgaagctga cggttattgt
    16981 gcgtaaagct tacggggcag gactttatgc aatggcaggc cccgcatttg agccagattg
    17041 ctgtattgcc ctatccaacg cacaaattgc cgtaatggga cctgaagcgg cggtaaatgc
    17101 agtatatgca aataagattg ctgcgcttcc aaaagaggaa caggcagact ttatcgcaga
    17161 gaagcgaaaa gagtaccaag aggaaattga cgtttatcgt ctagcatcag agctgattat
    17221 tgacgatgtc atagagccaa atgatttgcg taaagcactt gagactcgtt tggaactata
    17281 tatgtcgaag tatgttctat tctcacaacg aaagcacggc gtcaacccag tataaatatg
    17341 aaaaccgttt taaaagccga gtaaaaggtt tttaaaacgg ttttttgcta tatttacccc
    17401 attgcatagg taggcatatc gtattaaaat atgagatgga taaaagggag taggtggtga
    17461 tggagtggcg aaaaataata tagcgaatgt gcaggatgat accaagcttc cattgccgta
    17521 ccgcgtgtgg attgataaat attacatgga aataaaattc acaggttggc tactgtttag
    17581 tgtttactct tgtatagcgt tttataaact agtgattgat cgtctagtaa acgttgtact
    17641 cgttttgttc cgtggagaat atacattagg tgaacttggt ctattcgatt atagtacgtg
    17701 gcgtggaaca actaattttg taccgtttga tacgatcatg cgatacataa attactcaca
    17761 gtattttaat atagatttaa ttgttgttaa tttacttggg aacttattga tttttacacc
    17821 gatgggcttt ttgctaccgt tattatcgaa gcgttttcga agagtatggc cggtaattct
    17881 tattggattt ctctcaagcc tagctgtgga aacggtacaa tttattttca gagtgggttc
    17941 gacggatatt gatgatttaa ttttaaatac ggctggtgct tttattggtt acgtagctta
    18001 taaatgtatg ttgcagtttt caaaaagtaa ataaataact tcttaaggct acgtaaaatc
    18061 cacgtagctt tttttgtgga aataaaaagc cttaagacct atgcaagaag gttcattttt
    18121 aactatctgt aaaaaagtag ggaagaccac tttagtttat ttgtgaaaat tccgataata
    18181 agtgtacaga ttctgtttag tgggtaaaag tgtagttaat aaaaagttca tatatattaa
    18241 ataacttaca tattataggg agtagaggtg aatactatga aaatttctgg tttaatccaa
    18301 caagagagaa ttgcagcctt agaggatcgt agaaaaatcc tacaacgtaa aggggttgga
    18361 gatgtatatc gcaaaaatct ccagtatttt caaccaaaga aaaaccccgc tttaatagag
    18421 ttagagaatc tattgtttgg tcataaagat catgatttgt atgaaaaaca taaagaagaa
    18481 tcgaaagaag tcacacatca agaacaggca accattcgag aaatgcaaca aactgaaaaa
    18541 agtgtgcgtg cacatgagca ggcacataaa gcagttggtg gggatgtaac gggcccaatt
    18601 tcgtatacac atacaacagg ccctgaaggc gagcgataca ttacaggtgg cgaagtttct
    18661 attacagctg gagctggatc aactgaagaa gaaacgcttc aaatcttaga aaaagttaga
    18721 agcgcagcgt tagcacctgt agatccttca ccgcaagatt tacgtgtagc agcgagtgct
    18781 ggtgagcaaa ttcagcaagt gcaggcaaaa ctaaatggta ctgaaataga agaaactaat
    18841 gatttggatg aagagccagc gtttgttcga gaaccgattg aaataaaggt accggagcga
    18901 ttctcaaaag aattgaaatt agacccattt gcagatacaa ttttcggtag gagctatgag
    18961 gaatcgtata tggcgaacat ttttaaacat gtagccgcta aatatacagc acattctgaa
    19021 atggcgaaga acggctatct accgaggtat gaacctacgt tttcgtggac agcctaattg
    19081 cataaatggg ggattttcac atggctaaag cgaaacatgt taaaacaaat gcagtgcgac
    19141 tattagagca acaaaaaatt cagtttgatg tgatggaata tgagactggt gatggtcaag
    19201 tggacgggat ttctgtagct gaaaaaattg gacatcccgt ttctcgtgtg ttcaaaacat
    19261 tagtggctaa ggcaagtgca caaaaactat ttgtctttgt tattcccgtt gcggaagaac
    19321 tcgatttaaa agcagcggca aaagtcgttg gggaaaagaa aattgagatg ctacctgtga
    19381 aggaattact tgggtatact ggctatgtac gcggtggttg ttcaccaatt ggtatgaaga
    19441 aattgtatcc cacggttatt gatgaatctg cgcgtgagca agggagtatc attgtgagtg
    19501 caggtaaaat aggcatgcaa atacacgtcc agattgatga tttactggcg gtgacgaaag
    19561 ggcaacttgc cccaattacg accatccatg attaatttta tggatggttt ttttattttc
    19621 atttatctca gcagctagtg agataaatga agaaaaaatc tccggaggat ggaaaaaata
    19681 tgatacagta aagcaatctt atacataagg ggaagtttgt aaaatgcgaa gggttattgg
    19741 atggcgttgg acgtttttta ttgccgggat gttgattatg tcgctcggta ttacgatgtc
    19801 gattaaaggg aaagttattg gaacaagtcc atgggatgtg ttacatgtag ggttattcca
    19861 aaacttcggt ttaactattg gcacatggtc aattttaacg ggactactta ttatcacatc
    19921 gacatcattg gtgctaaaag aatggccgaa actgggcact tggttaaata tgttcttgat
    19981 cggactgttt attgatgtgt ttaattggct attgcccgcg actgatgttt atgtgttaca
    20041 aatcgcatat tttgtagttg gtgtgtttat attaagcttt ggctgtggaa tgtatatcgc
    20101 accaaatatg ggagcgggtc cacgagatac actaatgatg atacttgtag aaaaatttgg
    20161 tgggaccatt aaaagtgcac gaatgggcat tgaagtatta gtaacgattt tgggcgggct
    20221 acttggtggg ccagttggta tcggaacagt tttaattgcg ctaacatcag gttacattgt
    20281 gcaatattca ttaccgtatt gtcgaaaagt gttactgaaa tgcattggga atatggaagg
    20341 cgtaaagcca ttttattaaa attatcgggc tacttttatc aaatatgata aaagtagctt
    20401 ttcatgtttt taggagatgc gtcatataat gcagggcaga aggtaaaggg ggaaggacaa
    20461 tgaacggaaa tgttacttat tattatggac atgcactgac gggacagggg agaaagcatt
    20521 tatataaaga aatgatggac gaagcagcgc ttgtttatat actgcaaggg gcaccgacct
    20581 atagagggtc agagctatta aaagagcttg gctatttcta tgtgaaacaa ggttttgcgg
    20641 tagaatggtt caaacatgca ttgctcgaag agattgtgga agcggtcttc atacgagaat
    20701 gtaattatct ttttgtatgg tcttcagagt ggaatcttga gccatcatta ctgggcacaa
    20761 aacatcgcgt tatttctttc tatgactgtt tggaagaaaa acagttagaa ggtgtaggcg
    20821 ggcagttggc tacagccatg agggaccggg aactatggcg tgaaaaatgt atttgtatgt
    20881 tagagattgc aaagaaattg catgatgact gggaagtggt tacgcaaagt tgtatggact
    20941 ggcaagcatt agatgaccag attactagtt tgaagacaga tcttttccaa tcgatgacac
    21001 tcaacaaaac aggcatacgt acacatcgtt tacttggaac tttaacgcca actggtgcgc
    21061 aaaacacagt ggaaagcatg acgaaaaatt taaaacgacg gttgatgatt aaaggaaagc
    21121 caggtacagg taagtcttca ttaatgaaga gcttggcaga tgaagcaaat acaaggggac
    21181 tagatgctca aattgtttgg tgtggccttg atgcagggtc agtagatatg atcattattc
    21241 ctgagttgaa cttttgtatt ttcgatagta cagatccgca tattttcgat ccggaagaag
    21301 gacgcagtgg ggatgccatt ttcgatatgg gtcagcattg caagctaaca gaagaggcag
    21361 aggcggaaat tgaagatatt cgtgcagcct ataaagagtc catgcaaaat gcaatgggtt
    21421 atgcggtacg atatgcagaa gtagagcata cgattcgtca actaatggac cgttgcttgt
    21481 cgacatcagc gtggcgagaa aaaactgcgc cattatttca aagattacga aaatgaatta
    21541 ttttaataga gtatgaatgt gctaaactag gaacaagtac ggttttttag aaaggacgat
    21601 actagtgtct aaaatattaa atgcattttt agatgaaaac ttacaagcct tacgtgagca
    21661 aggtttatac aatgaaattg acccagtaga aagtgcaaac ggaccagtta ttcaggtgcg
    21721 tggcaaacaa ctcattaacc tatcttccaa taactattta ggtttagcaa caaatgacga
    21781 attaaagcgc attgccaaag aagcgacaga taaatatggt gtaggggcag gggcagtacg
    21841 tacaattaac ggtacacttg accttcacgt aaaactagaa gaaaagctag cagaatttaa
    21901 aggaacagaa gcggcgattt cttatcaatc gggctttaat tgtaatatgg cagcaatttc
    21961 tgctgttatg gataaaaatg atgccattct atccgaccag ttaaatcatg cttcaatcat
    22021 tgatggctgt cgattatcac gtgcgaaaat catcgcatac aatcactctg atatggatga
    22081 tttacgtgcg aaagcaaaag atgcaacgga atcaggtttg tacaacaaag tgatggttat
    22141 tacagatggt gtgttctcaa tggacggcga tattgccaag cttccagaaa tcgtggaaat
    22201 cgcaaaagag ttcgacttaa tcacgtatgt ggatgatgca catggctctg gtgtaaccgg
    22261 taaaggcaag ggtacagtga agcatttcgg tttagaaaaa gaaatcgact tccaaatcgg
    22321 tacgttatca aaagcaattg gcgtagtggg cggttatgta gcaggtaaga agaacctaat
    22381 cgactggttg aaagtacgct ctcgtccgtt cctattctca acagctttac caccaggtga
    22441 tgtagcggct attaccgctg cagtacaaat gctcatcgat tctacggagc ttcatgataa
    22501 gctttgggat aacggggatt acttgaaagc tggacttgcg aaattaggct tcaatatcgg
    22561 taattcagaa acgccgatta cgccatgtat tattggtggt gagaaattaa cacaggaatt
    22621 ctcgcgcaga ctatttgaag aaggtgtcta tgcaaaatca attgtcttcc caacggtccc
    22681 agcaggtaca gggcgtgttc gtaatatgcc aactgcagcg catacgaagg aaatgcttga
    22741 taatgcacta gcgatttatg aaaaagtagg gcgcgaatta ggaattatac aataatattg
    22801 gaaacaggga tgccacaata aatgaggcat ccctcttttt tgaagagatt taaggttaag
    22861 acggataaag ttgtgaaatc gatggataaa aactccaaag tgacggttaa cttcggcttg
    22921 ccctaaatat ttgtctctat tttaggcttt caccaactgt aacttacgtg cctctgcaat
    22981 acttgaagca ccagcaagcg ctaacgatac tttaaattct tcgtaaatat tttgcatcac
    23041 ttgttcaaca cctgcttgcc cggctaatgc aagaccgtaa acaaatggac gaccaatcgc
    23101 aaccgcatct gcgccaagtg ctaatgcctt taacacatca atcccgctat acacgccgct
    23161 gtctaaaatg acaggtacgc gtcctgctac aacctccaca attgagggaa gtgcatctaa
    23221 gctgccgatg acaccatcta attgacggcc accatgattg gaaacgatga tcccatcgat
    23281 tccgttttcg agagcaagct gagcgtcgtc aggatgtaaa atgcctttta agtagattgg
    23341 cagcgttgtg cgcattttca gctctgcgac atgttcccac gtcatatgag ggtggtatat
    23401 attatcgatg actgaagcaa catagctgtc aaagctgtca tcaggtaaag cttctgtgaa
    23461 aacagggtct tgcatgtaat ttcctttggc aaaacctaat tttaatggag agaattgatt
    23521 gcgcacatct tctgttcgcc agccaagcat cactgtatca atcgtaagaa cgatggctga
    23581 gaagcctgct ttttcagcgc gttccaccat gctataggaa atatcctcgt tttttgacca
    23641 atacaattgg aagagacgcg tgctatttgg tgcggctttc gcaacgtctt ccattgaata
    23701 agtcgacact gtactttgga tgtatggtat cgataatttt tctgcagctt ttgcaacagc
    23761 aggttcacca tctggatgct ccatgccgtt cataccaact ggcgcaaaaa gaagcggtgt
    23821 tgggaaggtt ttgccgaaca atgaaatcga cgtgtctaac tgcgatacat ctcgtaaaaa
    23881 acgaggtgta atactatatt tttcgaaggc tgtacggttg ttacgaagtg tttgttcgtt
    23941 accagcacca gattgaatat aaccaaatgg acctacttct agtttttctt ttgcagcttt
    24001 ttctaagtct gaaaaggcga taggaaaggg cttttcagct ttgatgtttt gtaaaagtaa
    24061 atcactattt gtcatgataa tcacctaatc ctttttaagt ttattggcta cacggttacc
    24121 aaatgattga atgctttgta caagaatgat taataagaat accgtgacat acataatgtc
    24181 gacttcataa cgtaaatgac cgtagcggta ggcaaggtca ccaagaccac cagcaccgac
    24241 aagacctgcc attgcagttg caccgattaa gccgatcgtt gcaattgtta agccaagcat
    24301 catcgaaggg cgagcttcac gtaataatac atgccataca atttgtgtac gcttaatgcc
    24361 cattgctttg taagcttcta atacgcctga ttcaacttcg agtaaggcag tttcgattaa
    24421 acgcgctaaa taaggtgctg tataaatgac aagtggcacg atagctcctt ttactccaat
    24481 tgttgtgccg acaatctctt tcgttaatgg caaaataaag aataataaaa taatgaacgg
    24541 taccgagcga ataatgttga tgattaagtt taatagttga tagaaaaatt tattggcata
    24601 catttgccca gggcgtgtca gtacaagaag cgcgccaagg ggaacaccga taagtataga
    24661 aaataacagt gaaatactta ccatttggaa tgtttgtagg gctgcttcaa atataattt
//
