LOCUS       NZ_CP011522            22214 bp    DNA     linear   CON 05-MAY-2024
DEFINITION  Streptomyces sp. CFMR 7 strain CFMR-7 chromosome, complete genome.
ACCESSION   NZ_CP011522
VERSION     NZ_CP011522.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CFMR 7
  ORGANISM  Streptomyces sp. CFMR 7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8207742)
  AUTHORS   Sudesh,K.
  TITLE     Complete genome sequence of Streptomyces sp strain CFMR 7, a natural
            rubber degrading Actinomycetes isolated from Penang, Malaysia
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8207742)
  AUTHORS   Sudesh,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2015) School of Biological Sciences, University
            Science Malaysia, Minden, Gelugor, Georgetown, Penang 11800,
            Malaysia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Coverage                   :: 147x
            Sequencing Technology             :: PacBio RS
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001278095.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 02:27:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,124
            CDSs (total)                      :: 7,038
            Genes (coding)                    :: 6,918
            CDSs (with protein)               :: 6,918
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 35 of 120
            Pseudo Genes (incomplete)         :: 96 of 120
            Pseudo Genes (internal stop)      :: 7 of 120
            Pseudo Genes (multiple problems)  :: 16 of 120
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:05:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8091616
            Orig. end                         :: 8113830
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011522.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22214
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="37"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..22214
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22214
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12214](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12214)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    849..869
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.91"
                     /tool="antismash"
     misc_feature    complement(850..870)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.78"
                     /tool="antismash"
     gene            946..1506
                     /locus_tag="ABE83_RS33950"
                     /old_locus_tag="ABE83_34010"
     CDS             946..1506
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1224: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007445205.1"
                     /locus_tag="ABE83_RS33950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34010"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_053562487.1"
                     /transl_table=11
                     /translation="MSPRPMARPGGRSARVQEAVRAAVRDLLGEVGRDGLTVPLVAARA
                     GVTPSTVYRRWGDLRELLSDVAVEHLRPDADPADLGSLRADLDAWAEQFLDEMASPAGR
                     AYIRDALLGDPDGDNAGRCSAYAAQQIGVILDRATRRGEPAPDTETLIDRVVAPVMYRI
                     LFRPGHLDAAYVRGLVTHALGGQ"
     gene            complement(1511..3130)
                     /locus_tag="ABE83_RS33955"
                     /old_locus_tag="ABE83_34015"
     CDS             complement(1511..3130)
                     /NRPS_PKS="Domain: AMP-binding (8-437). E-value: 8e-65.
                     Score: 210.9. Matches aSDomain:
                     nrpspksdomains_ABE83_RS33955_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491125.1"
                     /locus_tag="ABE83_RS33955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34015"
                     /product="acyl-CoA synthetase"
                     /protein_id="WP_053562488.1"
                     /sec_met_domain="AMP-binding (E-value: 1.9e-68, bitscore:
                     229.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYNLADLFESVVDVVPDREALLYVDHPGTGAERRLTYLQLDAAA
                     NRIAHHLIGAGLRPGEHLGLHLYNGIEYLQTVLGALKARLVPVNVNYRYVQEELVYLYR
                     DADLAGLVFDGEFDERVAAASAQAPALRHLVRVGSGEAPPDLGAVPFTEAEASGSPSRG
                     FEPRSADDQFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGEPVKSPQELAERVAAG
                     GDGITFFPTPPLMHGTSTLTAFIGFNFGQRVVVHRKFVPEEVLRTIEREKVTSVSLVGD
                     AMLRPLIDALNGPLRGTDCSSLFSVSSSGAIMSDSVRAEFQALVPTVMLLNNFGSSESG
                     FNGTATADSGPERGFRVQVNARTAVVDPATYEPVAPGEVGRIAQRGHVPLGYYNDPAKT
                     ADTFFHKDGERWVLLGDMATVDADGIVTVLGRGSQCINTGGEKVYPEEVEQALKSHPDV
                     YDALVAGVPDARWGSRVAAVLELRQGAPALDLDAVQAHCRPRLAGYKIPRALVLADRIQ
                     RSPSGKADYRWAKAVAAAGTDG"
     aSDomain        complement(1820..3106)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ABE83_RS33955_AMP-binding.1"
                     /evalue="8.00E-65"
                     /label="ABE83_RS33955_AMP-binding.1"
                     /locus_tag="ABE83_RS33955"
                     /protein_end="437"
                     /protein_start="8"
                     /score="210.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FESVVDVVPDREALLYVDHPGTGAERRLTYLQLDAAANRIAHHLI
                     GAGLRPGEHLGLHLYNGIEYLQTVLGALKARLVPVNVNYRYVQEELVYLYRDADLAGLV
                     FDGEFDERVAAASAQAPALRHLVRVGSGEAPPDLGAVPFTEAEASGSPSRGFEPRSADD
                     QFIIYTGGTTGMPKGVMWRQEDLFFSGLGGGAPTGEPVKSPQELAERVAAGGDGITFFP
                     TPPLMHGTSTLTAFIGFNFGQRVVVHRKFVPEEVLRTIEREKVTSVSLVGDAMLRPLID
                     ALNGPLRGTDCSSLFSVSSSGAIMSDSVRAEFQALVPTVMLLNNFGSSESGFNGTATAD
                     SGPERGFRVQVNARTAVVDPATYEPVAPGEVGRIAQRGHVPLGYYNDPAKTADTFFHKD
                     GERWVLLGDMATVDADGIVTVLGRGSQCIN"
     CDS_motif       complement(1922..1969)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ABE83_RS33955_0002"
                     /evalue="3.10E-04"
                     /label="NRPS-A_a6"
                     /locus_tag="ABE83_RS33955"
                     /protein_end="403"
                     /protein_start="387"
                     /score="13.2"
                     /tool="antismash"
                     /translation="VPLGYYNDPAKTADTF"
     CDS_motif       complement(2564..2614)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ABE83_RS33955_0001"
                     /evalue="3.00E-06"
                     /label="NRPS-A_a3"
                     /locus_tag="ABE83_RS33955"
                     /protein_end="189"
                     /protein_start="172"
                     /score="19.8"
                     /tool="antismash"
                     /translation="FIIYTGGTTGMPKGVMW"
     misc_feature    3208..3221
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: weak, score: 17.99"
                     /tool="antismash"
     misc_feature    3224..3238
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.75"
                     /tool="antismash"
     misc_feature    complement(3228..3243)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 17.75"
                     /tool="antismash"
     gene            3297..4097
                     /locus_tag="ABE83_RS33960"
                     /old_locus_tag="ABE83_34020"
     CDS             3297..4097
                     /NRPS_PKS="Domain: ECH (9-258). E-value: 1.6e-53. Score:
                     173.5. Matches aSDomain:
                     nrpspksdomains_ABE83_RS33960_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956444.1"
                     /locus_tag="ABE83_RS33960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34020"
                     /product="crotonase/enoyl-CoA hydratase family protein"
                     /protein_id="WP_053563149.1"
                     /transl_table=11
                     /translation="MGGTEHLTVEREGATLVLTLNRPEARNALSLPMLVGLYDGWLAAD
                     ADDGVRSIVLTGAGGAFCSGMDLKALAGDGMAGQEHRERLTADPDLHWKAMLRHHRPRK
                     PVIAAVEGPCVAGGTEILQGTDIRIAGAGATFGLFEVRRGLFPIGGSTVRLPRQIPHTH
                     ALEMLLTGRPYTADEAASIGLIGRVVPDGTALEEALAAAERINACGPLAVEAVKASVYE
                     GAELTETEALAAELKRGWPVFATEDAKEGARAFAEKRPPVYRRA"
     aSDomain        3324..4070
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ABE83_RS33960_ECH.1"
                     /evalue="1.60E-53"
                     /label="ABE83_RS33960_ECH.1"
                     /locus_tag="ABE83_RS33960"
                     /protein_end="258"
                     /protein_start="9"
                     /score="173.5"
                     /tool="antismash"
                     /translation="EREGATLVLTLNRPEARNALSLPMLVGLYDGWLAADADDGVRSIV
                     LTGAGGAFCSGMDLKALAGDGMAGQEHRERLTADPDLHWKAMLRHHRPRKPVIAAVEGP
                     CVAGGTEILQGTDIRIAGAGATFGLFEVRRGLFPIGGSTVRLPRQIPHTHALEMLLTGR
                     PYTADEAASIGLIGRVVPDGTALEEALAAAERINACGPLAVEAVKASVYEGAELTETEA
                     LAAELKRGWPVFATEDAKEGARAFAEK"
     gene            4175..5131
                     /locus_tag="ABE83_RS33965"
                     /old_locus_tag="ABE83_34025"
     CDS             4175..5131
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382254.1"
                     /locus_tag="ABE83_RS33965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34025"
                     /product="OB-fold nucleic acid binding domain-containing
                     protein"
                     /protein_id="WP_053562489.1"
                     /transl_table=11
                     /translation="MTEILSAPLVVEFPFTRSLGPVQSAFLTGLRERTVLGVRTDDGRV
                     LVPPVEYDPVTANELRSLVRVAPTGTVTTWAWNPSPRRDQPLGTPFAWVLVRLDGADTA
                     LLHALDAPGPDAVHTGMRVRIRWAATRTGAITDIACFEPYDGEPGPTEPAPHEGEFTDP
                     VTGITVPARLDYVHTPGRAQSAYLKALEDHRTVGERCPACRKVYVPPRGACPTCGIATA
                     EQVEVGPRGTVTTFCIVNIKAAHTANLDIEVPYVYAHIALDGADLALHGRIAGIPYDQV
                     RMGLRVEPVWAEGARHPDHYRPTGEPDADYDTYKELV"
     gene            5132..6184
                     /locus_tag="ABE83_RS33970"
                     /old_locus_tag="ABE83_34030"
     CDS             5132..6184
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019761824.1"
                     /locus_tag="ABE83_RS33970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34030"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_053562490.1"
                     /transl_table=11
                     /translation="MRDVAIVAFAQSPHRRRTDELSEVDLLMPVLHQVLEATGLKANEI
                     GFTCSGSADYLAGRAFSFTMALDGVGAHPPISESHVETDGAWALYEAWVKIMTGEADTA
                     LVYAYGKSSPGQVRDVLTRQLDPYYLAPLWPDSVSLAALQAQALLDAGRTDRAALTAIA
                     TRSRTDATANPYAQLTGDVPAGDLLVHPLRTGDCPPIGDGAAAVVLAAGDTARALCARP
                     AWIRGIDHRIEAHALGVRDLTDSPSTRLAARHAGAFERPVDTAELHAPFTSQEVILRNA
                     LDLGDDVRVNPSGGALAANPIMAAGLIRLGEAAARIHRGASDRALAHATSGPCLQQNLV
                     AVLEGESAHG"
     gene            6177..7343
                     /locus_tag="ABE83_RS33975"
                     /old_locus_tag="ABE83_34035"
     CDS             6177..7343
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971158.1"
                     /locus_tag="ABE83_RS33975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34035"
                     /product="thiolase domain-containing protein"
                     /protein_id="WP_053562491.1"
                     /transl_table=11
                     /translation="MAEEPVAVVGIGQTKHVAARHDVSIAGLVREAAVRALEDAALTWS
                     DIDAVVIGKAPDFFEGVMMPELYLADALGAVGKPMLRVHTAGSVGGSTALVAANLVAAR
                     VHRTVLTLAFEKQSESNAMWGLSLPVPFQQPLLAGAGGFFAPHVRAYMRRTGAPDTVGS
                     LVAYKDRRNALKNPYAHIHDPDLTLEKVQASPMLWDPIRYSETCPSSDGACAMILTDRE
                     GAGRAPYRPAWVHGGAMRSEPTLFAGKDFVSPRAGRDCAADVYRQAGITDPRREIDAVE
                     MYVPFSWYEPMWLENLGFAAEGEGWKLTEAGVTELDGDLPVNPSGGVLSTNPIGASGMI
                     RFAEAALQVRGRAGDHQIDGATRAVGHAYGGGAQFFAMWLVGSQPPPG"
     gene            complement(7395..8963)
                     /locus_tag="ABE83_RS33980"
                     /old_locus_tag="ABE83_34040"
     CDS             complement(7395..8963)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491120.1"
                     /locus_tag="ABE83_RS33980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34040"
                     /product="hypothetical protein"
                     /protein_id="WP_053562492.1"
                     /transl_table=11
                     /translation="MTVEGTVSGLEERVAGRAWMVRLDPADRGGTAVRVSCGRPGCAPQ
                     VLPSAAVGRTAAVAHLATHLRAASGPRPEAYCACRAEDCHTHVRTDGPRDRAPASRCGG
                     PVVLAVINDRQGRWWRALECCARCAAAHPSAKVVATAPAAGPAPAAAGSPAGGARAVAP
                     RPPAQIGPQFSHAASAPAPVPEGVPAARPPRPRRKRRSGKIAQRIVPFDLHPVALREEL
                     IELGDLFRAYQQRPEPDLVELSELHSRKAKAFRTWAEVTGETELRLEAERAEQAAAAAL
                     LQHQQRTGQSPAGDGQVTSRLLPGLTQWDHARAILAHVAEHTPVPGAEARLLAVLLTLR
                     SALTGTGNLVGQDVRGLPLTDPEELIGRLVESGWLSFPGTVEELLASRPESPTPITIPS
                     LMPGEDGPGPFVFGRKTRPKLSGWAQRVVGDKKLRKKKTGADVRLLALALAVRTSADGR
                     LGADGEGVEVEPLAAWCCVEPEGLEALVEQLTVADWLTDAEFTADGLLRGRLTERVLPV
                     SCPLA"
     gene            9280..9780
                     /locus_tag="ABE83_RS33985"
                     /old_locus_tag="ABE83_34045"
     CDS             9280..9780
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018550733.1"
                     /locus_tag="ABE83_RS33985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34045"
                     /product="hypothetical protein"
                     /protein_id="WP_003971159.1"
                     /transl_table=11
                     /translation="MSFLRRRSAATPAGPDFDVLAMDPGDWPGNLGAGLLPAPDGSCQG
                     VFLRYDLYGGRGPAMIIGNLPEGSPARETEEGQVPFEVAQLLLALENDEPIEVVSSEDV
                     PVMQGDNLLIVRRVKLSESRIACVQFDRSDGVLVTIASWDRPITDDLYTLLKPLPAELF
                     QQG"
     gene            complement(10001..12214)
                     /locus_tag="ABE83_RS33990"
                     /old_locus_tag="ABE83_34050"
     CDS             complement(10001..12214)
                     /EC_number="4.2.3.-"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0046246 - terpene biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018515109.1"
                     /locus_tag="ABE83_RS33990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34050"
                     /product="terpene synthase family protein"
                     /protein_id="WP_053562493.1"
                     /sec_met_domain="T1TS (E-value: 3.2e-83, bitscore: 279.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQPFSLPDFYVPYPARLNPHVEAARTHTREWARGMGMLEGSGIW
                     EEKDLEAHDYALLCAYTHPDCSAEALSLVTDWYVWVFFFDDHFLELFKRTPDREGAKRY
                     LDRLPAFMPMERGAAMPEPENPVEAGLADLWERTIPAMSDAWRARFAVATENLLNESLW
                     ELSNINEGRIANPVEYIEMRRKVGGAPWSAGLVEYAANAEVPAAVAGSRPLRVLRDAFS
                     DGVHLRNDLFSYQREVEDEGENSNGVLVLEKFLGCTTQEAAEAVNDLLTSRLHQFENTA
                     LTELGPLCAEKGLDPAQTASVLAYVKGLQDWQSGGHEWHMRSSRYMNGGGAGEAVAGFG
                     MSAASIKFTLRSETARARSHSHRPFQHVGPSIVPELKLPFSTTLSPHLEGARLRLVDWA
                     RSMGILEAQPGVPGSHIWDEERILAIDLPLCAAGIHPDASPDELDLSSAWLAWGTYGDD
                     WFPVVHGRTRDLAGARLANERLSLFMPLDGEATPEPVNALERSLGDLWLRTAEPMDPDA
                     RRAFRTAIESMTESWLWELANQAQNRIPDPVDYTEMRRATFGSDLTMSLCRLAHGRKVP
                     EAVYRSGPMRSLENAAADYACLLNDLFSYQKEIEYEGEVHNGVLVVQNFFGVDYPTGVR
                     IVHDLMESRLRQFLHVAEVELPVLYDDFDLDAEAREVLTGYVQELRHWLAGILVWHRGC
                     RRYREEDLRRGHGSPQILAGPTGLGTSAAQVTRLMAELAGSRA"
     misc_feature    12316..12330
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 20.1"
                     /tool="antismash"
     misc_feature    complement(12335..12350)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.19"
                     /tool="antismash"
     gene            complement(12410..13087)
                     /locus_tag="ABE83_RS33995"
                     /old_locus_tag="ABE83_34055"
     CDS             complement(12410..13087)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971163.1"
                     /locus_tag="ABE83_RS33995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34055"
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="WP_053562494.1"
                     /transl_table=11
                     /translation="MPRTIRITRSHKLAAAVLVAAGSVTAITATGGQSEAQPTAATSSA
                     TAEKAATGAATAKESAAKKAAAENAAKKAAADAAAAKKAAAKERSEKQAANRSTERKAV
                     AAPKKAAPKAAPKKYANNLDGWIRESLDIMKKKNIPGSYEGLHRNIMRESSGNPNAVND
                     WDINARNGIPSKGLLQVIQPTFDAYHVKGTPKKLTDPVANITAAANYAADRYGSIDNVD
                     SAY"
     gene            complement(13610..14749)
                     /locus_tag="ABE83_RS34000"
                     /old_locus_tag="ABE83_34060"
     CDS             complement(13610..14749)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0016310 - phosphorylation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010060711.1"
                     /locus_tag="ABE83_RS34000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34060"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_053562495.1"
                     /sec_met_domain="APH (E-value: 5.2e-17, bitscore: 61.2,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYTASSSVSAPPRPLRPMGTGGGPYLAPHAGAPAQGLGGRTRRAA
                     GPGAGPLSGRIDLSGPQGAQVRMAIASVQRICPEFNPVQVLRRSGRSVLIVGATGRATA
                     VAKCLLDHSPAWTERFQHEIAAYRAFVRHRPPVRVPRLIAADPENCTLVIERMPGRVAA
                     LTRHPAEAPPRADIRAALGAIARVNAWRPPPGLFEAPLDYGSRIARYHELGLFTDRDLG
                     DLQKLLHGLAQAGGRQPMGQFCHGDALLSNILLSPTGPVLVDWEHAGWYLPGYDLATLW
                     AVLGDAPAARRQISQLAQARGPAARDAFLVNLMLVLTREIRNYETAVQRTMREAPPVSA
                     GQDRPGVLSSGEEQRLLLRRLHDDCAMARRAVRAAVGTR"
     misc_feature    complement(14423..14425)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            14981..16477
                     /locus_tag="ABE83_RS34005"
                     /old_locus_tag="ABE83_34065"
     CDS             14981..16477
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606686.1"
                     /locus_tag="ABE83_RS34005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34065"
                     /product="hypothetical protein"
                     /protein_id="WP_019762743.1"
                     /transl_table=11
                     /translation="MTGEPNTRLSDLFGLAGWSKGELARMVNRQAAAMGHPQLATDTSR
                     VRRWIDMGESPRDPVPEVLAALFTERLGRVVTIEDLGFGRRGRAGKRRDSGTERDPDQL
                     PWAPERTAAVLTEFTGMDLMLNRRGLVGAGAALAAGSTIAGPMYDWLHSDPVLAADAPR
                     ANEPQHADPAGLDRYEAAPVGSEEIEALEYSVEVFRAWDASRGGGLQRKAVVGQLNEVG
                     GMLAYRHPDHLQRRLWGVAANLAVLAGWMSHDVGLEPTAQKYFVIAAHAAREGGDRPRA
                     GEALSRAARQMVHLGRPDDALDLMKLAKSGSGDETLPRTQAMLRTIEAWAQAAMGKGQA
                     MRRTLGEAEDLFVSDKGDVPPPSWMQMFDEADLHGMQALAFRTLAEHDPAAAVIAQRHA
                     KQALELRVGGRQRSKLFDHISLASACFIANDPEQGDRYARLALISMGETSSHRTWDRLR
                     EMYRLTGQFAGHARIQDLREQIELSLPQSPIARKAKGAQA"
     misc_feature    15023..15038
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            complement(16671..18155)
                     /locus_tag="ABE83_RS34010"
                     /old_locus_tag="ABE83_34070"
     CDS             complement(16671..18155)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956434.1"
                     /locus_tag="ABE83_RS34010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34070"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_053562496.1"
                     /transl_table=11
                     /translation="MPSHLFADRPAPQPPAHDAVDALIHRARQLRGDVAAVGRDAAATD
                     EDDPQARWQRALCDLAVQHLDNLDQHLGQLKAGPPAQRSGARHAPAEDPSAGGLPPQRV
                     GSAEWNLLTDEVSWSEELYEIFGRPPGSPPLSLDDLPSVLLPDDQPKLTAMVTGCLVDG
                     RPMDGEFRIVLPDNRVRTLHMTGEPVLDAEGCTAAMWAVLRDVGELRRGEESVGRSRDA
                     AVRDEHHDTAPHEAALRDEPTGDTSPGHAEGAAVAEPQETVAPPWRGSLRLPPPGDRPG
                     TLDIAAHHLPSASGGLIGGDWYDAMELPDGRTLLTVGDLTGHALPATSAMSLVLGALRG
                     MAVAGIEPGALMGHLDHLLESSMRSALGSALCCRYDPAGGVLSWAQAGHPPPVLFRDGT
                     GRQLPPPDGVLLGAGSQVAYEQDDVRLLPGDVLVLHTDGLTRRDDRDAGPERLLALAPR
                     FAHARTAQECVRGVVEEFGGAERLDDACVLVARVGA"
     gene            18438..19262
                     /locus_tag="ABE83_RS34015"
                     /old_locus_tag="ABE83_34075"
     CDS             18438..19262
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018515114.1"
                     /locus_tag="ABE83_RS34015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34075"
                     /product="aminoglycoside phosphotransferase"
                     /protein_id="WP_053562497.1"
                     /transl_table=11
                     /translation="MPELPRVPLPPQSVLDAFGLRGVPEPLTGGQGRSVRVGGAVLKPA
                     EGAEEEAVWAASVLERLPRGAGFRVPRPLRSADGDAVVDGWTAAEFLDGRLGPQRQWPG
                     VLAAGRALHAALREEPRPGLLDRRTHPWAVADRVAWGEREADVVAELAEPFALLLSRWR
                     PVEAVAQLVHGDLTGNVLFAPGRDPAVIDFTPYWRPPLYAEAVVIVDGLLWYDLPPELL
                     AVGADDPRWHQMLIRALIFRLVALSGLAGPSWRAGETEAARFLAVAEAVERG"
     misc_feature    complement(19333..19347)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.29"
                     /tool="antismash"
     misc_feature    19334..19345
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.7"
                     /tool="antismash"
     misc_feature    complement(19334..19349)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            19424..19684
                     /locus_tag="ABE83_RS34020"
                     /old_locus_tag="ABE83_34080"
     CDS             19424..19684
                     /GO_component="GO:0005840 - ribosome [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491113.1"
                     /locus_tag="ABE83_RS34020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34080"
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="WP_019762747.1"
                     /transl_table=11
                     /translation="MKPRIHPVSRPVVFRDRAADVAFLTRSTADSGERVTWEDGNTYPV
                     IDVETSSASHPFYTGSRQVLDTAGRVERFRRRYGSDEAPRG"
     gene            complement(19909..20556)
                     /locus_tag="ABE83_RS34025"
                     /old_locus_tag="ABE83_34085"
     CDS             complement(19909..20556)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018524490.1"
                     /locus_tag="ABE83_RS34025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34085"
                     /product="YoaK family protein"
                     /protein_id="WP_053563150.1"
                     /transl_table=11
                     /translation="MLLSAGSGAADAFVFLCVGQVFAGVMTGNLVLLGASAAGAGEDGV
                     AVRVVTALTAYACGAASGALMARLHLAVVLLVEAVLLGAAAVLWGFGLVPSYGDRLGLL
                     ALVSLAMGIQGRARVTPTNYFTGTLTSLAGRAAARELGPGDGWVLGRLGAVVAGAGLAA
                     VTERWWSPGAALGAVVLVAGALALEGGRRGGWRAGPGRGKPRPDRGNPAGAA"
     gene            complement(20779..21279)
                     /locus_tag="ABE83_RS34030"
                     /old_locus_tag="ABE83_34095"
     CDS             complement(20779..21279)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003971171.1"
                     /locus_tag="ABE83_RS34030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34095"
                     /product="tetratricopeptide repeat protein"
                     /protein_id="WP_053562498.1"
                     /transl_table=11
                     /translation="MSAREKKDLLAETDRLREEGRAGEAREKLLALTARFPDDAEVAYR
                     TAWVHDVLGLESEAVAYYERSLAGTGLGAEERRGALLGLGSTYRVLGRYGQAVETLRGG
                     VEEFPDDGALKTFLAMALFNTEEHHEAMQLLLRLVASTSDDPYVQQYRPAIEHYAKDLD
                     ETM"
     misc_feature    21237..21251
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            21438..22130
                     /locus_tag="ABE83_RS34035"
                     /old_locus_tag="ABE83_34100"
     CDS             21438..22130
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018491110.1"
                     /locus_tag="ABE83_RS34035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_34100"
                     /product="VanZ family protein"
                     /protein_id="WP_239009282.1"
                     /transl_table=11
                     /translation="MTVLTVVLLGLVAFSVLLAKVTLTPSPASEDIVTSNLQPGRSLRQ
                     YAEDYTFLAACKQAGGNVLLGVPFGLLLPFLVPRRLRMISMTLLTAALMVLVELIQGAL
                     VTGRAFDIDDVILNTAGALFGYFLLGRRLSHRYHVYAHPSRAEAAKPVPEPRTAEPKAP
                     EPKARDAKTPDAKTAEPKAAKPKAASRTGTKTPAKAGTGARGAGGRPAGDATQPGSGRA
                     LLNRIRRR"
ORIGIN
        1 gagcagcagg gccggggtgt cggcgagcga gtcgagcagc cgggtccggg tccgggccgc
       61 gagagcgggg tcgaggtccg cgcagctgca gattccgggg tgcgcgagct ggacggggtg
      121 gtggatgctg tcgccggtga cgagcgcccg ctcgccgtgg ctgctcagct ccactgccac
      181 ctggcccggt gtgtggccgg gggtcggcag cagacgtacg cccggggcga tgtccgtccc
      241 cccgtcgggg acgtcgagca ggtcgaagag gcccgcctcc cggacggggt gcacggagtc
      301 ccggaacatc tgctgccgcg gctcgtccag ctcggcaccg gcccagtggt cccactcggt
      361 gcgcgaggtg agataccgcg cgttggggaa catgggcacc cagtcgtcgc cctcggcccg
      421 ggtgttccac cccacgtggt cggtgtggag gtgggtcagc acgacgagat cgacgctctc
      481 cggcgcgaag cccgccgccc gcagccgctc ctcgtacgcg gtctgctgct ggtgccaggc
      541 ggggttcgcc cgctgcttcc cgttgccgat gcccgtgtcg acgacgatcc gcaggccgtc
      601 cgcctcgacg gcgaaactgt ggctcgccag ccggagaacc ccctggtcgt cggcgaactc
      661 ggggagaagc cagggcactt gggtgacgag atcggcggtc gcctcgggca gcagccacgg
      721 cccggtctcc ggcgggaggg gcgtctcgtc gatgcgccgg acggtgtggt cgcccacgga
      781 ccacgtgggg gcggggcgcg tggatgccgg ttcggtcctg gctggcctga tcacgggggt
      841 cccctccaga gcagagctaa agcaatgtgt ttgcgttaag agacggtagg ccctaccgtc
      901 tcttaacgca aacacattgc ttttacgtat ccgaggaggg gccgcatgag ccccaggccg
      961 atggcccgcc ccggcggccg cagcgcacgg gtgcaggagg ccgtccgcgc ggcggtccgt
     1021 gacctcctgg gtgaagtggg ccgggacggg ctcactgtcc ccttggtggc ggcccgggcc
     1081 ggtgtcacgc cgtccaccgt ctaccgccgc tggggcgatc tgcgcgaact gctctccgac
     1141 gtcgcggtcg aacacctgcg cccggacgcc gaccccgccg acctcggcag cctccgcgcc
     1201 gacctcgacg cgtgggcgga gcagttcctc gacgagatgg cctccccggc cggacgcgcc
     1261 tacatcaggg acgcgctcct cggtgacccc gacggcgaca acgccggccg ctgctccgcg
     1321 tacgccgccc agcagatcgg cgtcatcctg gaccgcgcca cgcggcgcgg cgaaccggcc
     1381 cccgacacgg aaacgctcat cgaccgggtc gtggcaccgg tcatgtaccg catcctgttc
     1441 cgccccggcc acctggacgc cgcttacgtc cggggcctgg tgacacacgc cctcggcggg
     1501 cagtgacccc tcagccgtcc gtcccggccg ccgccaccgc cttggcccag cggtagtccg
     1561 ccttgccgct cggtgagcgc tggatccggt cggccaggac cagggcgcgc gggatcttgt
     1621 atccggcgag ccggggcctg cagtgggcct ggaccgcgtc caggtccaac gccggggctc
     1681 cctggcggag ttcgaggacg gccgcgaccc tgctgcccca gcgtgcgtcg gggacgcccg
     1741 cgacgagcgc gtcgtacacg tccgggtggg acttgagcgc ctgctcgacc tcctccgggt
     1801 agaccttctc cccgccggtg ttgatgcact gcgacccccg gccgagcacg gtgacgatgc
     1861 cgtccgcgtc cacggtcgcc atgtcgccca gcagcaccca ccgttcgccg tccttgtgga
     1921 agaaggtgtc ggcggtcttg gcggggtcgt tgtagtagcc gagcggtacg tggccccgct
     1981 gggcgatgcg gcccacctcg cccggtgcca ccggctcgta cgtcgccgga tcgaccacgg
     2041 ccgtacgggc gttgacctgg acccggaagc cgcgctcggg gccggagtcg gcggtcgccg
     2101 tgccgttgaa gccggactcg gaggagccga agttgttgag cagcatcacg gtcggcacca
     2161 gcgcctggaa ctccgcccgc accgagtccg acatgatcgc cccggagctg gagacggaga
     2221 agagcgacga gcagtccgtc ccgcgcagcg gcccgttcag ggcgtcgatc agcggacgca
     2281 gcatcgcgtc gcccaccagg gagacactgg tgaccttctc cctctcgatc gtccgcagca
     2341 cctcctcggg gacgaacttg cggtgcacga cgacccgttg accgaagttg aagccgatga
     2401 acgcggtgag cgtggacgtg ccgtgcatca gcgggggagt ggggaagaag gtgatgccgt
     2461 ccccgcccgc cgccacccgc tcggccagct cctgcgggct cttcaccggc tccccggtcg
     2521 gcgcgccgcc gccgaggccg gagaagaaca ggtcctcctg acgccacatc acccccttcg
     2581 gcatcccggt cgtgccgccg gtgtagatga tgaactggtc gtcagcggaa cggggttcga
     2641 agccgcgcga gggcgagccg gaggcctcgg cctcggtgaa ggggacggcc cccaggtccg
     2701 gaggcgcctc acctgaaccc acccggacca gatggcgcag cgccggggcc tgcgcggacg
     2761 ccgccgccac ccgctcgtcg aactcgccgt cgaagaccag ccccgccaga tccgcgtccc
     2821 ggtagaggta gaccaactcc tcctgcacat agcggtagtt gacgttcacc ggaaccagcc
     2881 gcgccttgag cgcccccagg accgtctgga ggtactcgat cccgttgtag aggtgcaggc
     2941 ccaggtgttc gcccgggcgg aggcccgcgc cgatgaggtg gtgggcgatc cggttggcag
     3001 cggcgtccag ttggaggtag gtgagacgcc gctcggcgcc cgtaccggga tggtcgacgt
     3061 acaggagcgc ctcacggtcg gggaccacgt ccacgaccga ctcgaacagg tcggcaaggt
     3121 tgtactccac cgttcctcct gaccccggat gactggcgac tcggccgtca ttagagcgcc
     3181 ggtcggcaca agtgggaagg ggcggcgtcg aaagaatctg actgacagtc agaaaactat
     3241 tgaactgtga acccgcctcc tgcaacctgt tccaggtccg cagaggggag ttcgtcatgg
     3301 gcggtacgga acacctgacc gtggagcgcg agggcgccac actggtgctc accctgaaca
     3361 ggccggaggc caggaacgcg ttgtcgctgc cgatgctcgt cggcctctac gacggctggc
     3421 tcgcggccga cgcggacgac ggggtccgct cgatcgtcct caccggcgcg ggcggcgcgt
     3481 tctgctccgg catggacctc aaggccctgg cgggcgacgg catggcgggg caggagcacc
     3541 gcgagcggct gaccgccgac ccggacctgc actggaaggc gatgctgcgc caccaccgcc
     3601 cgcgcaaacc ggtgatcgcc gccgtggagg gcccctgtgt cgccgggggc accgagatcc
     3661 tccagggaac ggatatccgt atcgccgggg cgggcgccac cttcggcctc ttcgaggtcc
     3721 gccggggcct cttccccatc ggcggctcca ccgtccggct gccgcgccag atcccgcaca
     3781 cccacgccct cgaaatgctc ctcaccggcc gcccgtacac cgccgacgag gccgcctcca
     3841 tcgggctcat cggccgcgtc gtccccgacg gcaccgcgct ggaggaggcc ctcgccgccg
     3901 ccgagcggat caacgcctgc ggcccgctcg ccgtggaggc cgtcaaggcc tcggtctacg
     3961 aaggcgccga gctgaccgag accgaggcgc tggccgccga actcaagcgc ggctggcccg
     4021 tgttcgccac cgaggacgcc aaggagggcg cccgcgcctt cgccgagaag cgcccgcccg
     4081 tctaccgccg cgcctgagcc cgctccccga gccgcgcgcc ccaagtcccc atccctgaga
     4141 ccggagttct gattcctgag cctaggagag agccatgacc gagatcctca gcgccccgct
     4201 ggtggtcgag ttccccttca cccgctccct gggccccgtc cagagcgcct tcctcaccgg
     4261 actgcgcgag cgcaccgtcc tcggcgtccg caccgacgac ggcagggtcc tcgtcccgcc
     4321 cgtcgagtac gaccccgtca ccgcgaacga actccgctca ctcgtccggg tcgcccccac
     4381 cggcaccgtc accacctggg cctggaaccc ctccccgcgc cgcgaccagc ccctgggcac
     4441 ccccttcgcc tgggtgctcg tccgcctcga cggcgccgac accgcgctcc tgcacgccct
     4501 ggacgccccc ggacccgacg ccgtgcacac cgggatgcgc gtccggatcc gctgggccgc
     4561 cacccgcacc ggagccatca ccgacatcgc ctgcttcgag ccgtacgacg gcgagccagg
     4621 gcccaccgaa cccgccccgc acgaggggga gttcaccgac cccgtcaccg gcatcaccgt
     4681 ccccgcccgc ctggactacg tccacacccc cggccgcgcc cagagcgcct acctcaaggc
     4741 cctggaggac caccgcaccg taggcgaacg ctgccccgct tgccgcaagg tctacgtacc
     4801 gccgcgcggc gcctgcccca cctgcggcat cgccaccgcc gaacaggtcg aggtcggccc
     4861 gcgcggcacc gtcaccacct tctgcatcgt caacatcaaa gctgctcata cggcgaatct
     4921 cgacatcgaa gtcccctacg tctacgccca catcgccctc gacggcgccg acctcgccct
     4981 ccacggccgc atcgccggca tcccgtacga ccaggtccgc atggggctgc gcgtcgagcc
     5041 ggtctgggcc gagggcgcac gccaccccga ccactaccgg cccaccgggg agcccgacgc
     5101 cgactacgac acgtacaagg agctggtgta gatgagagac gtggcgatcg tcgccttcgc
     5161 ccagagcccg caccgacggc gtacggacga actctccgag gtcgacctgc tgatgcccgt
     5221 cctccaccag gtgctggagg ccaccggcct caaggccaac gagatcgggt tcacctgctc
     5281 cggctccgcc gactacctcg ccgggcgcgc cttctccttc accatggcgc tcgacggcgt
     5341 cggcgcccac ccgcccatct ccgagtccca tgtcgagacg gacggggcct gggcgctgta
     5401 cgaggcctgg gtgaagatca tgacggggga ggccgacacc gccctcgtct acgcgtacgg
     5461 caagtcctcg cccggccagg tccgcgacgt cctcacccgc cagctcgacc cctactacct
     5521 cgcccccctc tggcccgact ccgtctccct cgccgccctc caggcgcagg cgctcctcga
     5581 cgcgggccgc accgaccggg ccgccctcac cgccatcgcc acccgcagcc gcaccgacgc
     5641 caccgccaac ccctacgccc agctcaccgg agacgtcccc gccggggacc tcctcgtgca
     5701 cccgctgcgc accggcgact gcccgcccat cggtgacggc gccgccgccg tggtcctcgc
     5761 cgccggggac accgcccgcg ccctctgcgc ccgccccgcc tggatccggg gcatcgacca
     5821 ccgcatcgag gcccacgccc tcggcgtccg cgacctcacc gactcaccct ccacgaggct
     5881 cgccgcccgg cacgccggag ccttcgaacg gcccgtggac accgccgagt tgcacgcccc
     5941 gttcacctcg caggaggtga tcctccgcaa cgccctcgac ctcggcgacg acgtccgtgt
     6001 caacccctcc ggaggagccc tcgccgccaa cccgatcatg gccgcgggcc tcatccggct
     6061 cggtgaggcc gccgcccgca tccaccgggg cgcgtccgac cgggcgctcg cccacgccac
     6121 ctccgggccc tgcctgcagc agaacctggt cgccgtcctg gaaggggaga gcgctcatgg
     6181 ctgaggagcc cgtcgcagtc gtcggcatcg gccagaccaa gcacgtcgcc gcccggcacg
     6241 acgtctccat cgccggactg gtccgcgagg cggcggtccg cgcgctggag gacgccgcac
     6301 tgacctggag cgacatcgac gccgtcgtca tcggcaaggc ccccgacttc ttcgagggcg
     6361 tgatgatgcc ggagctgtac ctcgcggacg cgctcggagc cgtcggcaag ccgatgctcc
     6421 gcgtccacac ggccggttcg gtcggcggct cgaccgcgct cgtcgccgcc aacctggtcg
     6481 ccgcccgcgt ccaccggacc gtcctgaccc tcgccttcga gaaacagtcc gagtccaacg
     6541 ccatgtgggg cctttccctg cccgtcccct tccagcagcc gctgctggcc ggggccggcg
     6601 gcttcttcgc cccgcacgtc cgcgcctaca tgcgccgtac gggagcaccc gacacggtcg
     6661 gctccctcgt cgcgtacaag gaccgccgca acgcgctcaa gaacccctac gcgcacatcc
     6721 acgacccgga cctcaccctg gagaaggtcc aggcgtcccc catgctctgg gacccgatcc
     6781 gctactccga gacctgcccc tcctccgacg gggcctgcgc gatgatcctc accgaccgcg
     6841 agggcgcggg ccgcgccccg taccggcccg cctgggtgca cggcggcgcg atgcgcagcg
     6901 aaccgaccct cttcgcgggc aaggacttcg tctccccgcg ggcgggccgg gactgcgccg
     6961 ccgatgtcta ccggcaggcc gggatcaccg acccgcgccg ggagatcgac gccgtcgaga
     7021 tgtacgtccc gttctcctgg tacgagccga tgtggctgga gaacctcggc ttcgccgctg
     7081 agggcgaggg gtggaagctc accgaggcgg gcgtcaccga actcgacggc gacctccccg
     7141 tcaacccgtc gggcggggtg ctgtccacca accccatcgg cgcctccggc atgatccgct
     7201 tcgccgaggc ggcgctccag gtacggggac gggcgggcga ccaccagatc gacggggcca
     7261 cccgggcggt cggccacgcc tacggcggcg gggcgcaatt cttcgccatg tggctcgtcg
     7321 gctcacagcc cccgccgggg tgacggcccg ggcccgggcc tcccgggcgc accctgggag
     7381 gcaccggcac cggctcacgc cagtgggcag ctcaccggca gcacccgttc ggtgagccgc
     7441 ccccggagca ggccgtcggc ggtgaactcc gcatcggtga gccagtccgc caccgtcagc
     7501 tgctccacca gcgcctccag cccctcgggc tccacgcagc accaggcggc gaggggctcc
     7561 acctcgacgc cctccccgtc ggcccccagc cgcccgtcgg cgctcgtccg tacggccagg
     7621 gccagggcca gcagccggac atcggcgccg gtcttcttct tgcggagctt cttgtcgccc
     7681 accacccgct gggcccagcc gctcagcttg gggcgggtct tgcggccgaa gacgaacgga
     7741 cccgggccgt cctcgccggg catcagggac gggatggtga tcggggtggg gctctccgga
     7801 cgggaggcga gcagctcctc gaccgtaccg gggaaggaga gccagccgct ctccacgagc
     7861 cggccgatca gctcctcggg atccgtcagg ggcagccccc tgacgtcctg ccccaccagg
     7921 ttgccggtcc cggtgagcgc cgagcgcagg gtcagcagca ccgccaggag gcgggcctcc
     7981 gcgccgggca ccggggtgtg ctcggcgaca tgggcgagga tcgcccgggc gtggtcccac
     8041 tgcgtgaggc cgggcagcag ccggctggtg acctgaccgt cgcccgccgg gctctggccg
     8101 gtgcgctgct ggtgctggag gagggcggcg gcggccgcct gctcggcgcg ctccgcctcc
     8161 agccgcagtt cggtctcccc ggtgacctcc gcccaggtcc ggaaggcctt ggccttgcgg
     8221 gagtggagct cggacagctc gaccagatcc ggttcggggc gctgctggta ggcgcggaag
     8281 agatcgccca gctcgatcag ctcctcgcgc agggcgacgg ggtgcaggtc gaacggcacg
     8341 atccgctgcg cgatcttccc ggaccggcgc ttgcgacggg gccggggggg acgggccgcg
     8401 ggcaccccct cggggacggg ggccggggcc gacgcggcat gggagaactg cgggccgatc
     8461 tgggcgggcg gccggggcgc gacggcccgg gcccctcccg ccggggaccc ggccgccgcc
     8521 ggggcaggtc cggcggccgg ggcggtggcg acgaccttgg ccgaggggtg ggcggccgca
     8581 cagcgcgcgc agcactccag ggcccgccac cagcggccct gtcggtcgtt gatgacggcc
     8641 aggacgaccg ggccgccgca ccgcgacgcc ggggcccggt cgcgggggcc gtcggtccgt
     8701 acgtgggtgt ggcagtcctc ggcccggcag gcgcagtacg cctcgggccg ggggcccgac
     8761 gcggcccgca gatgcgtcgc caggtgcgcg acggcggcgg tacggccgac ggcggcggac
     8821 ggcaggacct ggggggcgca gcccggacgc ccgcacgaga cgcgtaccgc cgtaccgccc
     8881 cggtcggccg ggtccagacg caccatccac gcgcgtcccg ccacccgctc ttccagcccg
     8941 ctcactgtgc cctccaccgt catcctgtcc tcttctccgg cgcatcgccg tacccgtctc
     9001 gcggcgcacc gccgttcccg cagccaccac tgccacggcg gaccgggcgc ggcggtgatc
     9061 caacggtatg cggcacatgg gcccgtcgtg caggaacttg cgccgattcc acgcggaaga
     9121 gtcgagggtg tgcccgaacg tgcgccgacg cggtgccggg agggtaaggg ccggggcgcc
     9181 gcgcacgatt ccggccggtg gccggaaggc cgggcccggg gcggcggccg ggcccgggcc
     9241 cggctccgca acgtgagccg ggccacgtac catgtcagca tgtccttcct ccgccgccgc
     9301 agcgccgcaa cacccgcggg cccggacttc gatgtcctgg ccatggaccc gggggactgg
     9361 cccggcaatc tgggcgccgg tctgctcccc gcgcccgacg gaagctgcca gggcgtcttc
     9421 ctccgttacg acctgtacgg cggccgtggc ccggccatga tcatcggcaa tctcccggag
     9481 ggctcgcccg cccgcgagac cgaggagggc caggttccct tcgaggtcgc gcagctgctg
     9541 ctggctctgg agaacgacga gccgatcgag gtcgtcagca gcgaggacgt tcccgtgatg
     9601 cagggcgaca acctgctgat cgtccgccgg gtgaagctct cggagagccg tatcgcctgc
     9661 gtccagttcg accgcagcga cggcgtgctc gtcaccatcg cgagctggga ccggcccatc
     9721 accgacgatc tctacaccct tctgaagccc cttcccgccg agctgttcca gcagggctga
     9781 aacgtcactg cataggccgt ccgaatatgc cgggcggcct ttttcatgcc ctgtcccttc
     9841 tcatgcgtgg cctctcttcc atgaccgacc acgggagcgt ccggtcaccg gagcgtccgg
     9901 ccccgggagc gtcccggcat ggcgaacggc ccgccgcgcg tgtgtgccgc gacgggccgt
     9961 gcggcgtacg gcggtggccg tgccgtccgc gggccgggaa ctacgccctg ctgcccgcca
    10021 gttccgccat cagccgggtc acctgggccg ccgaggtgcc gagcccggtc ggcccggcga
    10081 ggatctgcgg ggagccgtgc ccgcgccgca ggtcctcctc gcggtagcgg cggcagcccc
    10141 ggtgccagac gaggatgccc gcgagccagt gcctcagctc ctgcacatag cccgtcagca
    10201 cctcccgcgc ctcggcgtcg agatcgaagt cgtcgtacag caccgggagt tccacctccg
    10261 ccacatgcag gaactgccgc agccgggact ccatcaggtc gtgcacgatc cgtacacccg
    10321 tcggatagtc gacgccgaag aagttctgca cgaccaggac cccgttgtgc acctcaccct
    10381 cgtactcgat ctccttctgg tacgagaaca ggtcgttgag caggcacgcg tagtccgcgg
    10441 ccgcgttctc cagcgaccgc atcgggccac tgcggtagac cgcctccggc accttcctgc
    10501 catgggcgag ccggcacagg ctcatcgtca ggtccgaacc gaaggtcgcc cgccgcatct
    10561 cggtgtagtc gaccggatca gggatacggt tctgcgcctg gttggccagc tcccacagcc
    10621 agctctcggt catcgactcg atcgcggtcc ggaaggcgcg ccgcgcgtcc gggtccatcg
    10681 gctccgccgt ccggagccac agatcgccca gcgaccgctc cagcgcgttc accggctccg
    10741 gggtggcctc gccgtccagc ggcatgaaga gcgagagccg ctcgttggcc agccgggccc
    10801 ccgccaggtc cctggtccgc ccgtgcacca cggggaacca gtcgtcaccg tacgtacccc
    10861 aggccagcca cgccgaggag aggtccagct cgtccggcga cgcgtccggg tggatgcccg
    10921 ccgcgcagag ggggaggtcg atcgcgagga tccgctcctc gtcccagatg tgcgagcccg
    10981 ggacccccgg ctgcgcctcc aggatgccca tgctgcgtgc ccagtcgacc agccggagcc
    11041 gggccccctc cagatgcggg ctcagagtcg tggagaacgg cagcttcagc tcggggacga
    11101 tggaggggcc gacgtgctgg aagggccggt ggctgtggct gcgggcccgt gccgtctccg
    11161 agcggagggt gaacttgatg gaggcggcgg acatgccgaa gcccgccacg gcctctccgg
    11221 ccccgccgcc gttcatgtag cggctggagc gcatgtgcca ctcgtggccg ccggactgcc
    11281 agtcctggag ccccttgacg tacgcgagga cggaggcggt ctgcgccggg tcgaggccct
    11341 tctccgcgca gagcgggccc agttcggtga gggcggtgtt ctcgaactgg tggagccgcg
    11401 aggtcagcag gtcgttgacg gcctcggctg cctcctgggt cgtgcacccg aggaacttct
    11461 ccaggaccag gaccccgttg ctgttctcgc cctcgtcctc gacctcgcgc tggtacgaga
    11521 agaggtcgtt gcgcaggtgc accccgtcgg agaaggcgtc ccgcaggacc cgcagcgggc
    11581 gcgacccggc gacggcggcg ggcacctcgg cgttcgccgc gtactccacg agcccggccg
    11641 accagggggc gccgccgacc ttgcggcgca tctcgatgta ctcgacgggg ttggcgatgc
    11701 ggccctcgtt gatgttggag agctcccaca gcgactcgtt gaggaggttc tccgtcgcca
    11761 ccgcgaaccg ggcgcgccac gcgtccgaca tcgcggggat cgtccgctcc cacaggtcgg
    11821 cgaggcccgc ctcgacgggg ttctccggct cgggcatggc cgccccgcgc tccatcggca
    11881 tgaaggcggg cagccggtcc agatagcgct tggcgccctc acggtcgggc gtgcgcttga
    11941 acagctccag gaagtgatcg tcgaagaaga agacccacac gtaccagtcg gtgaccaggg
    12001 acagggcctc ggccgagcag tcggggtggg tgtaggcgca gagcagggcg tagtcgtgcg
    12061 cctcgaggtc cttctcctcc cagatgccgg atccctccag catccccatc ccgcgtgccc
    12121 actcccgggt atgtgtccgt gccgcctcca catgagggtt gagccgggcc ggatacggaa
    12181 catagaagtc cggcagtgag aagggctgtg ccatgtgcga taggcctttc cggaaggctc
    12241 cgcgcggcga gggcgcggat cgatggtgtc cgcgccagcc ctacccttcg gccaaccggg
    12301 gcacgcacca gagggattag tcagataatc gcggtctggt ctgcgcctat tgggcgtgcc
    12361 tcttcggcgc gcccgctcgg tgtggcggtc cgctcagtgt ggtgtcggct cagtacgcgg
    12421 agtcgacgtt gtcgatcgag ccgtaccggt ccgcggcgta gttggcggcg gcggtgatgt
    12481 tggcgaccgg gtcggtgagc ttcttcgggg tgcccttgac gtggtacgcg tcgaaggtcg
    12541 gctggatcac ctggagcagg cccttggagg ggatgccgtt gcgcgcgttg atgtcccagt
    12601 cgttgacggc gttcgggttg ccgctggact cacgcatgat gttgcggtgc agcccctcgt
    12661 aggagccggg gatgttcttc ttcttcatga tgtcgagcga ctcgcgtatc cagccgtcga
    12721 ggttgttcgc gtacttcttg ggagcggcct tgggggcggc cttcttggga gcggccacgg
    12781 ccttgcgctc ggtggagcgg ttggcggcct gcttctcgga gcgctccttc gcggcggcct
    12841 tcttcgccgc ggcggcatcg gcggccgcct tcttcgcggc gttctccgcc gcagccttct
    12901 tagccgcgct ctccttggcc gtcgcggcgc cggtggcggc cttctcggcg gtggcggagg
    12961 acgtggcggc ggtgggctgc gcctcgctct gcccgccggt cgcggtgatg gccgtgacgg
    13021 aaccggccgc gacgagcacg gcggcggcga gcttgtggga gcgggtgatg cggatggtgc
    13081 ggggcatgcg tagctcttcc tgtgggggac ggggcctgcg gccatgggcc gcgtgagcag
    13141 agaccgagag atgtcggccg cgaccgccgt agggcgctcg tcgcaggctc ggtctcggtg
    13201 cttgccggga tccatggtta acggccgccg acacaggagg caatgaccct atttactagg
    13261 gcaagtagtt gatagggagg aatatccctt ttggtgtttt cgtcgcgccg caggggaggg
    13321 gtcgcaccca ctaccccggc tcgtaggtga cgtgggtctc gtggcgcgcc tcacccggtg
    13381 acgcccctcg ggtggcaatc ggtcagcgct ccatcaccgt gcggtacgcc ctccgcgggc
    13441 ttcgtccgcc ggcccgcgcc cgcgcccgcg cccgccacgc cgtacccgta cgcccccgcc
    13501 cctgtccccg cccccgtccg gacacagcac agcgcgctgc gggaccggtg tgtcggcacc
    13561 tgtcccgcag cgcgcttccc ttacacagtg gctttctcgt cgtccggact cagcgcgtcc
    13621 cgaccgccgc ccgcaccgcc cgccgcgcca tcgcgcagtc gtcgtgcagc cgccgcagca
    13681 gcagccgctg ctcctcgccc gaggagagca cccccggccg gtcctgcccc gcgctcaccg
    13741 ggggcgcctc gcgcatggtg cgctggacgg ccgtctcgta gttacggatc tcgcgggtca
    13801 gcacgagcat caggttcacc aggaaggcat cccgcgcggc cggccccctg gcctgcgcga
    13861 gctggctgat ctggcgccgc gccgccgggg cgtcgcccag caccgcccac agcgtcgcga
    13921 ggtcgtagcc cggcagatac cagcccgcgt gctcccagtc gaccagcacc gggccggtcg
    13981 gcgacagcag gatgttggag agcagtgcgt caccgtggca gaactggccc atgggctgac
    14041 ggccgcccgc ctgggccaga ccgtgcagca gcttctgcag atcgcccagg tcccggtcgg
    14101 tgaacaggcc cagctcgtgg tagcgcgcga tccgtgagcc gtagtcgagc ggcgcctcga
    14161 acagcccggg cggcggccgc caggcgttca cccgggcgat cgccccgagc gcagcccgga
    14221 tgtcggcccg cggcggggcc tccgccggat gccgggtcag cgcggccacc cgtccgggca
    14281 tccgctcgat caccagcgtg cagttctccg gatccgccgc gatcagccgg ggcacccgta
    14341 ccggggggcg gtgccggacg aacgcgcggt atgccgctat ttcgtgctgg aaccgttccg
    14401 tccaggcggg ggagtggtcc agtaaacact tggccacggc ggtggcccgc ccggtggcgc
    14461 ccacgatcag tacggaacgg ccgctgcgcc gcagcacctg gaccgggttg aactcggggc
    14521 agatgcgctg cacggaggcg atggccatcc gcacctgcgc gccctgcggc ccggagaggt
    14581 cgatcctgcc gctgagaggt ccggcacccg gtcccgccgc ccgccgggtc cggccgccca
    14641 ggccctgcgc cggtgcaccg gcgtgggggg cgagatacgg cccgccgccc gtccccatgg
    14701 gacggagcgg ccggggcggg gcggacacgg aggacgatgc tgtgtacatg ggcgagacag
    14761 atcccttcgt gcgccgacaa gttacgtacg ccaacccggc cgacggccgt tcggcaccct
    14821 ggggagtacc tagggctgcc gggcggggtg gcgctttcct acctgacaac gagtcacggg
    14881 tggcagacca tctggcggac cctggcgaac cctggcgaat agtcacagcg catctgacag
    14941 ggggttagtg tcaagtcagc cgagaacctg ggggcttgac gtgaccggag aacccaacac
    15001 ccgtctttcc gacctgttcg gcctggccgg ctggtccaag ggcgaactcg cgagaatggt
    15061 gaacaggcag gcggcggcca tgggccaccc gcagctggcc accgacacct cgcgggtcag
    15121 gcgctggatc gacatggggg agtccccccg tgatcccgtg cccgaagtgc tggcagccct
    15181 gttcaccgag cggctcggcc gtgtcgtgac catcgaggac ctcgggttcg gccgacgcgg
    15241 gcgtgcaggg aaacggcgtg attccgggac ggaacgcgat cccgatcaac tgccgtgggc
    15301 gcccgagcgg acggcggcgg tcctcaccga attcacggga atggacctca tgctcaaccg
    15361 acgcggcttg gtgggtgcgg gcgccgcgct cgccgccggc tcgaccatcg ccggccccat
    15421 gtacgactgg ctgcacagcg accccgtcct ggcggccgac gcaccacgcg ccaacgaacc
    15481 acagcacgcc gaccccgccg gtctcgaccg gtacgaggcc gcgcccgtgg gctccgagga
    15541 gatcgaggcc ctggagtact cggtcgaggt gttccgcgcc tgggacgcct cccggggcgg
    15601 cgggctccag cgcaaggccg tggtgggcca gctcaacgag gtgggcggca tgctcgccta
    15661 ccgccacccc gaccacctcc agcgccgcct gtggggcgtc gccgccaacc tcgccgtgct
    15721 cgcggggtgg atgtcccacg acgtcggcct cgaacccacc gcccagaagt acttcgtcat
    15781 cgccgcccac gcggcccgcg agggcggcga ccggccgcgc gccggtgagg cgctctcccg
    15841 cgccgcccgc cagatggtcc acctgggccg tccggacgac gccctcgacc tgatgaagct
    15901 cgccaagtcc ggctcgggcg acgagaccct gccccgtacg caggcgatgc tgcgcaccat
    15961 cgaggcctgg gcgcaggcgg cgatggggaa gggccaggcc atgcggcgca ccctcggtga
    16021 ggccgaggac ctgttcgtct cggacaaggg cgacgtgccc ccgcccagtt ggatgcagat
    16081 gttcgacgag gccgacctgc acggcatgca ggccctggcg ttccgcacgc tggccgagca
    16141 cgacccggcc gccgccgtca tcgcccagcg ccacgccaag caggccctgg agctgcgggt
    16201 gggcgggcgt cagcggtcca agctcttcga ccacatctcg ctcgcctcgg cctgcttcat
    16261 cgccaacgac cccgaacagg gcgaccggta cgcgaggctc gccctgatct cgatggggga
    16321 gacctcctcg caccgcacct gggaccggct ccgcgagatg taccggctca ccggccagtt
    16381 cgccgggcac gccaggatcc aggacctccg cgagcagatc gagctgtcgt tgccgcagag
    16441 cccgatcgcc aggaaggcca agggggccca ggcgtgaact ccgtacgggt ccgccggcgg
    16501 agaccgtaac cgccgcgcgc acctgccgtc ctgacgcccc gacgacgtga cgtccggacg
    16561 ccctgtcccc gacggtctcc cgtcatggca cccggtggtc ttccctcccg acgctccggc
    16621 gctcctccgt cacggagtcc ggcagccccg ggggccggcc ccgcgccccg tcacgccccg
    16681 acccgggcga ccagcacaca ggcgtcgtcc aggcgctcgg ccccgccgaa ctcctcgacc
    16741 acgccccgca cgcactcctg tgccgtacgg gcgtgtgcga accggggggc gagggcgagc
    16801 agccgctccg ggcccgcatc ccggtcgtcg cgccgggtga ggccgtccgt gtgcagcacc
    16861 agcacatctc cggggagcag ccgcacgtcg tcctgttcgt acgcgacctg ggacccggca
    16921 ccgaggagga ccccgtccgg gggcggcagt tgccgtcccg tcccgtcacg gaagagcacg
    16981 ggcggcgggt gtcccgcctg cgcccaggag agcaccccgc ccgcagggtc gtaccggcag
    17041 cacagggcgc tgcccagggc ggaccgcatc gacgattcga ggaggtggtc gaggtgaccc
    17101 atcagggcgc ccggctcgat accggcgacg gccatgccgc gcagtgcgcc gaggaccagg
    17161 gacatggccg aggtggcggg gagcgcgtgc ccggtcagat caccgacggt cagcagggtc
    17221 cggccgtcgg gcagctccat cgcgtcgtac cagtcgccgc cgatgaggcc gccggacgcg
    17281 gaagggaggt ggtgggcggc gatgtccagg gtgccggggc ggtctccggg cggcgggaga
    17341 cgcagtgaac cgcgccacgg cggcgccacg gtctcctgag gctccgcgac cgccgccccc
    17401 tccgcgtgcc cgggggacgt gtctccggtg ggttcgtcgc gcagggccgc ttcgtgcggg
    17461 gcggtgtcgt ggtgctcgtc gcgcacggcc gcgtcccggc tccggccgac gctctcctcg
    17521 ccccggcgca gctccccgac gtcccggagc acggcccaca tggcggcggt gcagccctcg
    17581 gcgtcgagga ccggttcgcc ggtcatatgg agggtgcgca cccggttgtc ggggagcacg
    17641 atgcggaact ccccgtccat cggccgcccg tcgacgaggc agcccgtcac catggccgtc
    17701 agtttcggct ggtcgtcggg gaggaggacg gacggcaggt cgtccaggga gagcggtggg
    17761 gacccggggg gccggccgaa gatctcgtac agctcctcgg accagctcac ctcgtcggtc
    17821 aggaggttcc attcggcgct gcccacccgc tgcggcggga gaccgccggc cgacgggtcc
    17881 tccgcagggg cgtgccgtgc gccggaacgc tgggcggggg gaccggcctt gagctgaccc
    17941 agatgctggt cgaggttgtc gagatgctgg acggccaggt cgcagagggc gcgctgccag
    18001 cgggcctggg ggtcgtcctc atcggtcgcc gccgcgtcac gtcccacggc cgccacgtcc
    18061 ccgcgcaact gccgggcgcg gtggatcagg gcgtcgacgg catcgtgtgc ggggggctgc
    18121 ggtgcggggc ggtccgcgaa cagatgggac ggcatctcgt actccgatac aggcgcggcg
    18181 cggccgggtc tcaggggcgg ccgctatcga ctttcgcaca ggccgcggcg gcccgtaagg
    18241 cattcgacaa cactcatccc gtagttgctt ctggcatatg ccgcgggctg cacggaagga
    18301 gtcgcactcc gaacgggcgt acggatgagg ggtgttggcg tgtccccgtg gcataggcgg
    18361 cccgtggtga tccccggtcg tagggcccga ccggaaatcg cgtgcgggtg gcggggcggc
    18421 ccggcaggat gccccgcatg cctgaactgc cgcgtgttcc gcttcccccg cagtccgttc
    18481 tcgacgcctt cggcctgcgt ggcgtccccg agccgctgac gggcggtcag gggcggagcg
    18541 tgcgggtcgg cggggccgtc ctgaagcccg cggagggggc ggaggaagag gcggtgtggg
    18601 ccgcgtccgt gctggagcgg ctgccccggg gtgccgggtt ccgggtgccc cggcccctgc
    18661 ggtcggccga cggggacgcc gtggtcgacg gctggaccgc cgccgagttc ctggacggac
    18721 ggctcggccc ccagaggcag tggcccgggg tcctcgcggc gggccgcgct ctccatgccg
    18781 ccctgcggga ggagccccgg cctggccttc tggaccgccg gacgcacccc tgggcggtgg
    18841 ccgaccgggt cgcctggggc gagcgggagg ccgacgtggt cgcggagctg gccgagccgt
    18901 tcgcgctgct gctctcccgg tggcggcccg tggaggcggt ggcgcagctc gtccacggcg
    18961 acctgaccgg caatgtgctc ttcgcgcccg gccgggaccc cgccgtcatc gacttcaccc
    19021 cctactggcg cccgcccctc tatgccgagg ccgtggtgat cgtggacggt ctgctctggt
    19081 acgacctgcc gccggaactc ctggccgtcg gcgcggacga cccccgctgg caccagatgc
    19141 tgatccgggc gctgatcttc cgcctcgtcg cgctgagcgg gctcgccgga ccctcctggc
    19201 gcgccgggga gacggaggcc gcccgcttcc tggcggtggc ggaggccgtc gagcgcggct
    19261 gatccggccc gggagtgccg agggatccgg cccgggaatg ccgacggggt gaggtgcgtt
    19321 gttcaagcag aacgaaaacg aatcccatct ccgttacggt gtcggcgcca ggctcccccc
    19381 ggaggctcgg ccgcccgctc cgcggcgagg aaggaacgca tcgatgaagc cccgtatcca
    19441 ccccgtctcc cgccccgtgg tcttccgtga ccgcgccgcg gacgtcgcct tcctcactcg
    19501 ctcgaccgcc gactccggtg agcgcgtgac ctgggaggac ggcaacacct accccgtcat
    19561 cgacgtggag acctcgtcgg cgagccaccc gttctatacg gggagccgcc aagtgctcga
    19621 cacggccggt cgcgtggagc ggttccgccg ccgttacggc tccgatgagg cgccgcgcgg
    19681 ctgatccgcc gcaccctgaa ccatcgacgg aaccaggggt tccgtgccat gggtcacatg
    19741 ggagggggcc ggttcctagg aacagtccaa gatggtttat cgttcatcta tacgtgggag
    19801 cgagcggaac ggcgtccccg ggtctcaccg gcaacccctg gggagagccc gtaaggccga
    19861 cgctcatcgg agccttccgc cgagaggtga ccgcgcttca ccccaccctc aagccgcccc
    19921 ggctggattc ccccgatccg gccggggctt ccccctgccc ggccccgccc gccacccgcc
    19981 gcgccgcccg ccttcgaggg ccagcgcccc ggccaccaga accaccgcac ccagcgcggc
    20041 ccccgggctc caccaccgct ccgtcaccgc cgcgagcccc gccccggcca ccaccgcgcc
    20101 cagccggccc agcacccagc cgtcgcccgg ccccagctcc cgcgccgccg cacggccggc
    20161 cagagaggtg agggtcccgg tgaaatagtt cgtcggcgtc acccgggcgc gcccctggat
    20221 ccccatcgcc agcgagacga gcgccagcag cccgagccgg tcaccgtacg acgggaccag
    20281 gccgaacccc cagagcacgg ccgccgcacc gagcaggacg gcctcgacca gcagcaccac
    20341 ggccaggtgg agccgggcca tcagggcacc ggacgcggcc ccgcaggcgt acgccgtcaa
    20401 cgccgtgacc acccgcaccg ccacaccgtc ctcgcccgcc cccgccgccg aggccccgag
    20461 cagcaccagg ttcccggtca tcacacccgc gaagacctgg cccacacaga ggaagacgaa
    20521 cgcgtccgcc gcgccggaac ccgcggagag gagcagcaga gtccactgac cgcgccggga
    20581 gaggccgccg gcccggggcg cggcggaggc gggcgaaggg gacgaggggg aggcgggcgg
    20641 gggaggggag tgcacgcgag cattctcgat aggtacgggc ccggggccgc actccacggc
    20701 cgacgcggcg cgccgcgaac ccgtgccccc gccgcccgta cccgccgccc cgagccgccg
    20761 tcacccgcaa cgcgccggtc acatcgtctc gtcgaggtcc ttcgcgtagt gctcgatcgc
    20821 cggacggtac tgctggacat acgggtcgtc gctggtcgac gccaccagcc gcagcagcaa
    20881 ctgcatcgcc tcgtggtgct cctccgtgtt gaacagggcc atcgccagga acgtcttgag
    20941 cgccccgtcg tccgggaact cctcgacgcc cccgcgcagc gtctccacgg cctgcccgta
    21001 ccgccccagc acccggtacg tactgccgag gccgagcagc gctccacgtc gctcctccgc
    21061 accgagtccc gtccccgcca ggctgcgttc gtagtacgcc acggcctcgg actccaggcc
    21121 caggacgtca tggacccacg cggtgcggta ggccacctcc gcgtcgtcgg ggaaccgggc
    21181 cgtcagggcg agcagcttct cccgcgcctc cccggcccgg ccctcctcgc gcagccggtc
    21241 ggtctcggcc agcaggtcct tcttctcacg tgcgctcata cgcccatcgt cgcaggcgcc
    21301 gccggacggc cgggcgattt tccgggccag ggcggccgac cgggtgtctt cggcccgggt
    21361 gggggcacca gtccgccatg actgcggaga cgaacactcc tgcgcgacag gggacatgga
    21421 cacgcgtact gctgagaatg accgtcctga cggtggtgct gctggggctg gtggccttct
    21481 ccgtcctgct ggccaaggtg acgctcaccc cgtcaccggc ctccgaggac atcgtcacct
    21541 ccaacctgca gccggggcgg tccctgcgcc agtacgccga ggactacacc ttcctcgccg
    21601 cctgcaagca ggcgggcgga aacgtgctgc tcggcgtgcc cttcgggctg ctgctgccgt
    21661 tcctcgtgcc ccgccgcctg cggatgatca gcatgacgct gctgaccgcc gccctgatgg
    21721 tcctcgtgga gctgatccag ggcgccctgg tgaccggacg cgccttcgac atcgacgacg
    21781 tcatcctcaa cacggcgggt gccctcttcg gctacttcct gctgggccgc cggctcagcc
    21841 accgctacca cgtgtacgcg catccctcgc gggccgaggc ggcgaagccc gtaccggagc
    21901 cgaggacggc ggagccgaag gcaccggagc ccaaggcgcg ggacgcgaag acgccggacg
    21961 cgaagacggc ggagccgaag gcagcgaagc cgaaggcggc ctcccgcacg gggacgaaga
    22021 cgccggcgaa ggccggaacc ggggccaggg gcgcgggcgg ccgcccggcg ggggacgcca
    22081 cccagcccgg ctccggccgc gccctgctga accggatccg caggcgctga ccgcgtccgc
    22141 acccccggca acagggcaca tcaaggcagt attcgctcac cgaggcggcg ggagcccacc
    22201 gaggcacccg gagt
//
