LOCUS       NZ_CP011522            25276 bp    DNA     linear   CON 05-MAY-2024
DEFINITION  Streptomyces sp. CFMR 7 strain CFMR-7 chromosome, complete genome.
ACCESSION   NZ_CP011522
VERSION     NZ_CP011522.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces sp. CFMR 7
  ORGANISM  Streptomyces sp. CFMR 7
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8207742)
  AUTHORS   Sudesh,K.
  TITLE     Complete genome sequence of Streptomyces sp strain CFMR 7, a natural
            rubber degrading Actinomycetes isolated from Penang, Malaysia
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8207742)
  AUTHORS   Sudesh,K.
  TITLE     Direct Submission
  JOURNAL   Submitted (18-MAY-2015) School of Biological Sciences, University
            Science Malaysia, Minden, Gelugor, Georgetown, Penang 11800,
            Malaysia
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 3
            Genome Coverage                   :: 147x
            Sequencing Technology             :: PacBio RS
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001278095.1-RS_2024_05_05
            Annotation Date                   :: 05/05/2024 02:27:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,124
            CDSs (total)                      :: 7,038
            Genes (coding)                    :: 6,918
            CDSs (with protein)               :: 6,918
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 120
            CDSs (without protein)            :: 120
            Pseudo Genes (ambiguous residues) :: 0 of 120
            Pseudo Genes (frameshifted)       :: 35 of 120
            Pseudo Genes (incomplete)         :: 96 of 120
            Pseudo Genes (internal stop)      :: 7 of 120
            Pseudo Genes (multiple problems)  :: 16 of 120
            CRISPR Arrays                     :: 10
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 16:05:14
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3663865
            Orig. end                         :: 3689141
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP011522.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25276
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="20"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25276
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25276
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15276](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15276
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(302..1168)
                     /locus_tag="ABE83_RS15015"
                     /old_locus_tag="ABE83_15045"
     CDS             complement(302..1168)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490593.1"
                     /locus_tag="ABE83_RS15015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15045"
                     /product="TIGR03084 family metal-binding protein"
                     /protein_id="WP_053559932.1"
                     /transl_table=11
                     /translation="MSDVAAVVDDLREESGELDALVGGLGEEAWRRVTPAEGWTVAHQI
                     AHLAWTDEVALLAATEPERFGDEVAKALAAPEAFVDEAADALVAAHAPHALLARWREGR
                     RQLDTVLREAPAGTRIPWYGPPMSVASMATARLMETWAHGQDIADALGVTRTPTARLRH
                     VARIGVRARNYAYAVRGIEAPGEEFRVELRSPGGDLIAYGPEGAAQRVTGPLLDFCLLV
                     TQRAHRSDLAVTAEGSEADRWLSIAQAFAGPPGPGRPPRAEQAEQAVRDEQAERAVRAE
                     RAVRGDR"
     gene            1368..1610
                     /locus_tag="ABE83_RS15020"
                     /old_locus_tag="ABE83_15050"
     CDS             1368..1610
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019763466.1"
                     /locus_tag="ABE83_RS15020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15050"
                     /product="CopG family transcriptional regulator"
                     /protein_id="WP_078562547.1"
                     /transl_table=11
                     /translation="MIKTTVYLPEDLEVRLDAEAAATGISKAELIRRGIALLLEHAERP
                     KRSRELPVFDSGRPRTPDEMDDSVYEHIKERAARR"
     gene            1607..2041
                     /locus_tag="ABE83_RS15025"
                     /old_locus_tag="ABE83_15055"
     CDS             1607..2041
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490591.1"
                     /locus_tag="ABE83_RS15025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15055"
                     /product="PIN domain-containing protein"
                     /protein_id="WP_053559933.1"
                     /transl_table=11
                     /translation="MIIVADTSALYAAFDAAQPEHSAAARILEHERLAISPLVVTELDH
                     LVHRDLGFPAALQVMEALNSRMDDGQYRLAELKLADLRTAHEVRQKYEGLRLDLADAVG
                     VVLADRYRTDRIFTLDQRDFRAMTPLTPGLDAFRIVPADY"
     gene            2169..2891
                     /locus_tag="ABE83_RS15030"
                     /old_locus_tag="ABE83_15060"
     CDS             2169..2891
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967200.1"
                     /locus_tag="ABE83_RS15030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15060"
                     /product="NUDIX domain-containing protein"
                     /protein_id="WP_053559934.1"
                     /transl_table=11
                     /translation="MTAEPHLVNPHFDGDRLVLEEHREADHVRYLFPGTGTGPGGPLRA
                     LTLTEALHARIGPAGTAEAVLRAWAQGAGPAEAVEVKVADPAAVPPVRVRAGAIVIRDG
                     HVLLIHFREPDEDGPHYEIPGGGVEAGETPEEAAVRELREETGLHGSVGRKVARVWKEG
                     RHEHYFLMTAEGSIGPAETLDTYGGTPVWIPVPDLPALPLWPRRLSWRIEHWHRTGWPT
                     PPAELADSITDLQAPCTW"
     gene            complement(2932..3903)
                     /locus_tag="ABE83_RS15035"
                     /old_locus_tag="ABE83_15065"
     CDS             complement(2932..3903)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1166: transporter,
                     EamA family"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510823.1"
                     /locus_tag="ABE83_RS15035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15065"
                     /product="EamA family transporter"
                     /protein_id="WP_053559935.1"
                     /transl_table=11
                     /translation="MNVQRSASEPAAAAAAVAVPEATPALDAAGRKDSGPGKGAALVPV
                     ALVVAGGLSVQFGSAVAALLMPKAGALGVVTLRLAAAALILLVVCRPKVRGHSRADWGT
                     VLAFGVAMGGMNTLFYQALDRIPLGIAVTLEVLGPLALSVFASRRLINVVWAGLALVGV
                     VLLGGGGFDRLDPVGAAYALGAGAMWAAYIVFSARTGRRFPQADGLALAMVVAAVLSLP
                     LGIWESGAKLTVPSTLALGAAVAVLSSVLPYTLELMALRRLPASTFAVMMSLEPAIAAA
                     AGFLILNQALSTTDALAIALVIGASMGAVRSQTGARKRKKTG"
     misc_feature    complement(4335..4348)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            4340..5185
                     /locus_tag="ABE83_RS15040"
                     /old_locus_tag="ABE83_15070"
     CDS             4340..5185
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003967204.1"
                     /locus_tag="ABE83_RS15040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15070"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_053562829.1"
                     /transl_table=11
                     /translation="MRHLRAFLAVAEEGNVTRAAAHLGLTQPAVSRTLAALERHLGLRL
                     VDRSTHHLALTPEGVAFRDKAAAAVAAFDEALDTGRLRHWPLRLGHAWSAFGPYTTPLL
                     RAWRERHPATPLELLRIDDRTAGLTRGEVDAALLRGPVHAPGLVTEVLFTEGRVAAVTA
                     DGPLASRTSLRLADLVDGPVVLNTVSGITTPELWPPHTRPAATLTVANTDDWLAAIAAG
                     RGSGVSAASTAAIHPHPGVAYVPLDDAPGVPVLLARRDGPGHPALPKLAALAREIVARG
                     "
     gene            complement(5358..5885)
                     /locus_tag="ABE83_RS15045"
                     /old_locus_tag="ABE83_15075"
     CDS             complement(5358..5885)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490587.1"
                     /locus_tag="ABE83_RS15045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15075"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_078949685.1"
                     /transl_table=11
                     /translation="MTKVIDLRHYGQGSFPEGFKQMLIDVHADAYADAMDNEFNQRFPW
                     FVDHWSGMDGFTCVVAFDGDEPTGFAYGAPLQPGREWWRSTAFAPNNGYTATYAVSEVM
                     VRPQWRRQGISERLHEALLEGRGEDLAVLLVDVTHPKVQDLYETWGYEKAGEQRPFADS
                     PVYAVMVKRLHA"
     gene            complement(5882..7135)
                     /locus_tag="ABE83_RS15050"
                     /old_locus_tag="ABE83_15080"
     CDS             complement(5882..7135)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380191.1"
                     /locus_tag="ABE83_RS15050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15080"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_053559937.1"
                     /transl_table=11
                     /translation="MGGNLVLQDRLEQLGLTQEELAARLNAALQEITGRPGDISSRTVR
                     NLLNGSSRRPIGRTCAALERVFGCPVADLGFSAPSSMQHPPEGPVRRRDFIASTTGTAA
                     AAVPVVKQRRSVGMTDVARASAGMNQLVEADDRQGGHASLAAAALEARAKVLELQQRNA
                     SERVRRALYALAAEFTTVAAWSCIDLRDLDKARTYLHESSTFAGLSQDPPTAMRVWVNM
                     AMLAYQRKNWPEQLAAAQAANASPAARRDPFFGSMGRVRLALAHSSLGDLRAARRSLGA
                     AQENYRKAAEDERPRWTAFYGPAELNHLAAIILNHNGEPAEAEAMAYRSLARIPAEFQR
                     NRALATCQLALAQLRQGEPEQATATAGTVFTIMEGVPLPGRMRTLIGDFHRDLFRLAPS
                     TTYARDWADRMRDEWSRT"
     misc_feature    complement(6914..6916)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7374..7799
                     /locus_tag="ABE83_RS15055"
                     /old_locus_tag="ABE83_15085"
     CDS             7374..7799
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380190.1"
                     /locus_tag="ABE83_RS15055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15085"
                     /product="ATP-binding protein"
                     /protein_id="WP_053562830.1"
                     /transl_table=11
                     /translation="MTVAQPNAIDSPGYAAEVPCVRESVSLARAFVSQVLAVWGMDDDV
                     TGWGKAIVTELLANAVEHTETPVSRIHIARPSNGAVRIGVSDRSHGAPRLKTADLNAES
                     GRGLSLVAAMSSQWGYDMHSWGKDTWAVVETPVGRER"
     gene            7796..8215
                     /locus_tag="ABE83_RS15060"
                     /old_locus_tag="ABE83_15090"
     CDS             7796..8215
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380189.1"
                     /locus_tag="ABE83_RS15060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15090"
                     /product="DUF6415 family natural product biosynthesis
                     protein"
                     /protein_id="WP_053559938.1"
                     /transl_table=11
                     /translation="MSTAVAPKPPAQEWTPPLDADGLRLVLERFRAWDPLDIEEVFDDL
                     DAAIGSQPPPVASAVALLGRLRRHLKQLSNITVADDNFPPSAEMTRLVERGVPLLEEPT
                     PAGYRQAVGLARRLAFVTADLIEVLIEARYVKEIE"
     misc_feature    7862..7864
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8433..9668
                     /gene="fxlM"
                     /locus_tag="ABE83_RS15065"
                     /old_locus_tag="ABE83_15095"
     CDS             8433..9668
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490583.1"
                     /locus_tag="ABE83_RS15065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15095"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_053559939.1"
                     /sec_met_domain="PCMT (E-value: 9.9e-36, bitscore: 122.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTNTTVEPDEATRLRNKVVDELRAGGDISSSEIEAVMRKVPRHAF
                     IPDTPLDKAYDTYAAVITKTDEHGVQLSSVSAPQIQAMMLEQAQVKPGMRVLEIGSGGL
                     NAAYLAELVGEDGDVVTVDIDPVVTERAQRLLDEHGYGRVRVVTADAAEPIPELGEVDV
                     VMVTAGAWDIAPAWTAQLKQGGRLVVPLRMRGLTRSVAFTQITGEHGPYLESVSALICG
                     FVPMQGSTAHREELLLVNGTPEIGLKFDDGLPADPHRLDNAVTFPRHELWTGVVIGLSE
                     LVDTLQMAMAISLPGFCTMAVDEDLDTGLVAPVNKRFALAAVEDDTFAYLVTRRTEDNK
                     HIEYGVHALGPNAEQFADQVADVLRDWEASRRGGPSPVIRVYPVNTSDDQIPAGRVIDK
                     VHSRVSLSWPSA"
     gene            9724..9915
                     /locus_tag="ABE83_RS15070"
                     /old_locus_tag="ABE83_15100"
     CDS             9724..9915
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380187.1"
                     /locus_tag="ABE83_RS15070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15100"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_053559940.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.1e-14, bitscore:
                     52.7, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSATLSPPAPLAGLDDDFAPLDVKVVIAEHAYGKLMCSTGDGCG
                     TTCATGASACGSFTEDPA"
     gene            10001..13066
                     /locus_tag="ABE83_RS15075"
                     /old_locus_tag="ABE83_15105"
     CDS             10001..13066
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012380186.1"
                     /locus_tag="ABE83_RS15075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15105"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_053559941.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.6e-199,
                     bitscore: 661.7, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 5.7e-17,
                     bitscore: 60.9, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3e-10, bitscore:
                     38.8, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVSRAVADYRWQGAAMLRATTSTGPADIPRTLDLDNVAVTRGWLN
                     RVWEGDGFRNALELATPVLSDAVEAVVQGRQSEPRHVRRTAVSTVSYLLRWQHRPIPLG
                     LFAGTAPVTVGPRASARWRDKHRVLIRPDSEWVTDMVLRLQRIPALLARLPLVANNAAR
                     TRGDRLVAPGPPSDGHAVLLAPVEISVRNARPVAAAMDAARSPIPYGALCGHLRDSFPQ
                     ATPEQIDGLLTGLVEQQFLITSLWAPMTTVDPLQHLCHELEQHDADSIPDVRDLVHKLY
                     ALRDEVSAHQPTLSDISVSALATRMRALTAVTPTPLLIDTALDCETQLPQTVIAEAQAA
                     VSALYRTTPQPYGYQHWRDYHRRFRARYGVGALVPVMDLVADSGLGLPAGYVGSERGAS
                     LKVRTDRDELLLSLMQQVLLDGRDELRLTDDMVHALEKAAGTDERLFVPRVEAAFEIHA
                     PSTRALSSGTFDLLLTAVPRPGSSMAGRFAHVLPPEHQDALATSYRGAPDRLAAQLVFP
                     PRRHRNENVTRTSRLLPHIIELSGHQELDETTIRLADIAVTADPRSFHLVQLSTGRPID
                     VRVLHALEGGTQTPPLARFLTEVANGRYAAYKPFDFGAGSRLPYLPRVRYRRTILTQAR
                     WLLMAEDLPARKAPRKEWEDAFTAWRDRLRVPMQVAVIEYDQRLPLDLSHPVHLRVLRA
                     HLDNARRVELREVPDADAHGWIGRAHEIWLSLDRSDPDTPYVPRPRSTTSPGAQRHLPG
                     GGNVLHAQLHAHPRRYDEILSHHVPHLLSAFGEEPPTWWFTRHREMARPDADQHLDLTL
                     LLSPDSYGVGAQHVRAWADSLHAMGLASGLALATYQPQTGRFGHGPAMDAAHQVFAADS
                     AAALAQIQLAERTDALAPQALAAASALHLVTPLAPNAAAAEEWLVGNLPQGTGRLDRTL
                     RGQVLELTGPNGASALASLPGGRQVAEAWRARAAAVDFYRTALVSERHPLDVARSLLHQ
                     HHVRALGVDPRTEETTIRLVRTAALQHRMADR"
     misc_feature    10448..10450
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     aSDomain        10469..10744
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_ABE83_RS15075_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.30E-19"
                     /identifier="RREFam001.1"
                     /label="ABE83_RS15075"
                     /locus_tag="ABE83_RS15075"
                     /protein_end="248"
                     /protein_start="156"
                     /score="60.9"
                     /tool="antismash"
                     /translation="VANNAARTRGDRLVAPGPPSDGHAVLLAPVEISVRNARPVAAAMD
                     AARSPIPYGALCGHLRDSFPQATPEQIDGLLTGLVEQQFLITSLWAP"
     gene            13063..14302
                     /locus_tag="ABE83_RS15080"
                     /old_locus_tag="ABE83_15110"
                     /pseudo=""
     CDS             13063..14302
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490581.1"
                     /locus_tag="ABE83_RS15080"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15110"
                     /product="lanthionine synthetase C family protein"
                     /pseudo=""
                     /sec_met_domain="LANC_like (E-value: 2e-32, bitscore:
                     111.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTPATAATTILGQYTADLAEPPAPPPEEPWAVQSLADGAAGISL
                     LHMEIASRYGGSWRSAHRWITSAASGPISAADQAGLFLGAPAVGFVLTAVPPAYRHLYA
                     SARTTLHQHITGLAHRRVDAALARIGRGDLPTFAEYDLFYGLTGIGAYLLRTEPEGPAL
                     ERILQYLVALTRPLAADGRGLPGWWVRHDPARGESPHFPGGHGNFGAAHGITGPLLLLA
                     QAMRRGVTVHGHQDAMFTICAHLDAWCQHGDSGPWWPEHISRHDLDRGQPHHDAPARPS
                     WCYGTAGIARADQLAGIALRSPMLQKFYEDALYRALSDPARLTLITDNGLCHGWAGIYQ
                     TAHRSPRSRRRGRRTAAHPPGPSRSRPHRLRPARHLLDSRPDQRRGRHRTRPHHVRLEA
                     GTEHWMGRMSLDQL"
     gene            14392..15276
                     /locus_tag="ABE83_RS15085"
                     /old_locus_tag="ABE83_15115"
     CDS             14392..15276
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03891.1"
                     /locus_tag="ABE83_RS15085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15115"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_239009312.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 2.6e-32, bitscore:
                     111.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPVVLSDAVAVYNQAGREALLHHAATTDWWQTYLHFTGWSNADG
                     TFAAHVLPILRAAEAAGAVDGWWYTRKHPCWRLRLRIQSVNDAKLTIRDGFDRLVSEGR
                     LQRWWPGIYEPETPAFGGMTSMTAAHALFVTDSREIQQLRLRDDLAIGPRELSVLLCTI
                     MMRAARLEWYEQGDVWDRVITTEHRSAVSDVPPEQLNARAQEIRHLLLADSDTLLRPGG
                     PLEPVDEWVAAFHSVGQTLANGVQDGTLDRGLRQVLSYHVIFHWNRLGLSLRGQSILAR
                     AARGAVLQDESPW"
     misc_feature    14857..14859
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15619..16158)
                     /gene="cpt"
                     /locus_tag="ABE83_RS15090"
                     /old_locus_tag="ABE83_15120"
     CDS             complement(15619..16158)
                     /codon_start=1
                     /gene="cpt"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490579.1"
                     /locus_tag="ABE83_RS15090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15120"
                     /product="chloramphenicol phosphotransferase CPT"
                     /protein_id="WP_053559943.1"
                     /transl_table=11
                     /translation="MIVLNGGSSSGKSGIVRCLQALLPDPWLALGTDTMVEAMPAALQA
                     AETGIVFGPDGSVSIGSEFRDLEDAWTEGVAAMARAGARIIVDEVFLSGAAGQRRWSER
                     LGGLGVLWVGVRCAGEVAAGREIARGDRTVGMAAAQAESVHRGVVYDLEVDTTRTESLE
                     CARTIAAHVRGEGAGR"
     gene            complement(16217..19153)
                     /locus_tag="ABE83_RS15095"
                     /old_locus_tag="ABE83_15125"
     CDS             complement(16217..19153)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1138: FAD linked oxidase domain protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490578.1"
                     /locus_tag="ABE83_RS15095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15125"
                     /product="FAD-binding and (Fe-S)-binding domain-containing
                     protein"
                     /protein_id="WP_203228179.1"
                     /transl_table=11
                     /translation="MAELHRPHTGPPAPPADFAAALRTAVRGGTDFGATARALTTMDAS
                     NYRRVPLGVLAPRDADDIAAALTVCQEYGVPVVPRGGGTSIAGQATGTGLVLDLTRHLN
                     AILDVDPAARTATVQPGVVLDDLRAAAAPYGLTFGPDPSTHSRCTLGGMIGNNSCGAHS
                     VAWGTTADNVRALEVVRYGGEALRLEQTRGMGPDGVRGTSAHGPHGVRELIGAHLALLR
                     TGYPDLPRRISGYALDALLPEHPGGPDPVRAFCGSEGTLAVVTEATVRLVETPRARALA
                     VLGYADEAAAAEAAPGLLPYGPLTVEGMAADLVREPAGLPRGAAWLFVETGGATPAEAR
                     AQAERVLRSADAVDGTVVTDPAGQRALWRIREDAAGTATRMPDGSEAWPGWEDCAVPPA
                     RLGPYLRDFRALLTQHALRGTPYGHFGEGCIHVRIDFDLLTPPGIARFRAFSEELADLV
                     VAHGGSLSGEHGDGQARAELLPRMYGDELVALFGAFKDLWDPDGGLNPGILARPAPLDT
                     NLRFEVLPKRPVDVAFGYPQDGGDFAGAVRRCVGVAKCRTAEAPSGGAGVMCPSFRVTG
                     DEEHSTRGRARLLHEMLAGEVITDGWRSTEVRDALDLCLSCKGCRSDCPVGVDMATYKA
                     EFLHHHYRGRIRPAAHYALGRLPQWLRLAAPFARPLNALARVRPLAALAKRLAGIAPER
                     TIPVLATETYSRWLRGHQGEGPGEGEGEGKVTRVLSPDRVVHLWADTFTEYLTPQVGRA
                     AVRVLEEATGRTVLPPPAGVCCGLTYVSTGQLDAARRVMRRTLDRFAPLPGHPVAVLEP
                     SCAATLRTDLPELLPDDPRAAELAARVRTLAQYLEEYAPDWTPPRLDRPVVGQTHCHQH
                     AVLGDAAERRLRERLGLTGELSGGCCGLAGNFGFEKGHWEVSVACAEEQLLPAVRESEP
                     GAELLADGFSCRTQLDRLGPPAGRRARHLAEVIAEGLEGGDGERPSRR"
     misc_feature    complement(19213..19227)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.81"
                     /tool="antismash"
     misc_feature    19214..19227
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.12"
                     /tool="antismash"
     misc_feature    complement(19218..19227)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.63"
                     /tool="antismash"
     misc_feature    complement(19307..19320)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 17.42"
                     /tool="antismash"
     gene            19404..21011
                     /locus_tag="ABE83_RS15100"
                     /old_locus_tag="ABE83_15130"
     CDS             19404..21011
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012379651.1"
                     /locus_tag="ABE83_RS15100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15130"
                     /product="ATP-binding protein"
                     /protein_id="WP_053559944.1"
                     /transl_table=11
                     /translation="MRPSFRPTALALLISAAVTGALTLWAVAAAPDAVRTPLAWGAAAA
                     AVLLSVCVAVTVHTLGTVRALRAQRAADNQRFTAETSRLVSASAAEAQRFTAETARIKA
                     AASAETARVTAEARAENERIAAEAAAEKARLSVTVDRLTARATRAETERSAAVAACANA
                     AGRMQALATSMLADLREMEHRHTDESVLGDLLHLDHRTAQAGRLADSIAVLTGARSGRR
                     WAKPIVMESILRGAMGRIGSYQRVRLHSTSDVAIAGHAAEGVMHALAELLDNAANFSPP
                     TAEVHVYVEEVPAGIVITVEDSGLVMSEVQLRRAEQAVSADHQNLTNLSGTRLGLAVVG
                     RLARKHGLTVSFRPSARGGTGALMMLPQDLISRTAAPALPDRAPAATPAAALPAATPSA
                     APVTAPTPATAPAEPEPSHASAAGAGLSGTVPAARSTAENQASDGSTPLTPAAEPQRTE
                     SESESTGSVPAFGESGLPKRRRGRTLAAAEARNGNAAHGGAETPQARTTDAKVQAARFS
                     TFSRAVRANSQHPEGNTR"
     gene            21008..21430
                     /locus_tag="ABE83_RS15105"
                     /old_locus_tag="ABE83_15135"
     CDS             21008..21430
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018510830.1"
                     /locus_tag="ABE83_RS15105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15135"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_053559945.1"
                     /transl_table=11
                     /translation="MTATTDEKLNWLLEGLLDRTPGTRHALVLSRDGLKLCRTPELSVD
                     QADQLAAISAGIQSLSHGASIEFGDGTGGVRSAMAEFYGGVLFIVEAGAGAHLAVVADE
                     DSDVGLVGHNMSELVEQLGEHLVAPPRTPVAESSAV"
     gene            21427..21798
                     /locus_tag="ABE83_RS15110"
                     /old_locus_tag="ABE83_15140"
     CDS             21427..21798
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015610481.1"
                     /locus_tag="ABE83_RS15110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15140"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_018490575.1"
                     /transl_table=11
                     /translation="MTTAPRPRPGRDDDPDRLYTLTGGRSRSDSAAFDLVTLVVAECDP
                     APGMQSEHVAILRMCQSPTAVVEISATLNLPVSIVRIMLCDLLDTGRVSARHPRTARVA
                     DRLPDPDILEQVLVGLRNL"
     gene            21779..22462
                     /locus_tag="ABE83_RS15115"
                     /old_locus_tag="ABE83_15145"
     CDS             21779..22462
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010071692.1"
                     /locus_tag="ABE83_RS15115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15145"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_053559946.1"
                     /transl_table=11
                     /translation="MDSATSDRATLSDTADNGLKIVVVGGFGVGKTTMVRSVSEIRPLN
                     TEETMTRAGEAVDHLDGVQAKTSTTVAFDFGRITLDARSVLYLFGAPGQERFWFLWDRL
                     FSGTLGAVVLVDTRRLADSWYAIDRLEHHGTPFIVACNDFGGPLHSEQQIREALDLADD
                     VPLVECDARDRSSSKYVLITLVEHLAALSAARLRAPDATVPGADVPGAAVPAGALAGPT
                     PEPAP"
     gene            22459..23910
                     /locus_tag="ABE83_RS15120"
                     /old_locus_tag="ABE83_15150"
     CDS             22459..23910
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490573.1"
                     /locus_tag="ABE83_RS15120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15150"
                     /product="cytochrome P450"
                     /protein_id="WP_053559947.1"
                     /transl_table=11
                     /translation="MTTTSDTTGTTGPTASDPATAAQTGTTASGSTATGTTAATGTTGP
                     AASGAPGPAAAPGSAAPTRSAPSGCPVAHGSVPLSGPRFQSDPVQLYRDMRRDHGAVAP
                     VVLDGDVPAWLVLGYRELHQVTGDPVLFSRDSELWNQWDRIPDDWPLLPMIGRRQNSIL
                     YTVGERHSVRAMMISNALEGVDPFSLKRYAEEFADELIDRFCTKGAVDIIAEYTKLLPA
                     LVLARIYGYPEEVIRPLVGSINDITDGLDRAIAGSQHLGMATFQLLAEKHAEPGDDVVS
                     RMIADEGGFTDEEIVQDLLVMIVAGHQPTADWMGNSLRLMLTDERFAASLSGGRHSVAE
                     AMNEVLWEDTPTQNVAGRWASRDTHLGGRHVRAGDLLLLGIAAANGDPQVRTHASALTG
                     GNNAFLSFGHGEHRCPFPAQETAEVIARTGIEVLLDRLPDMDLAVPAEQLTRRPSPWLR
                     GLTDLPVLFTPTPALGRPASFGGPA"
     gene            23907..25136
                     /locus_tag="ABE83_RS15125"
                     /old_locus_tag="ABE83_15155"
     CDS             23907..25136
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019766990.1"
                     /locus_tag="ABE83_RS15125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ABE83_15155"
                     /product="cytochrome P450"
                     /protein_id="WP_053559948.1"
                     /sec_met_domain="p450 (E-value: 3e-14, bitscore: 51.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRIALDPFVRDLDGESAALRAAGPLAEVELPGGVHVYAVTHHAE
                     ARALLTDSRVVKDINVWNAWRRGEIPMDWPLIGLANPGRSMLTVDGADHRRLRTLVAQA
                     LTVRRVERLREGIEALTNASLEKLAAHPAGEPVDLKAEFAYPLPMNVISELMGVDAADH
                     PRLKELFEKFFSTQTPPQEFVQLMADLDTLFRRIIEDKRANPGDDLTSALIAASENGDH
                     LTDEEILNTLQLIIAAGHETTISLIVNAVKALQTHPEQRKKVLDGEIGWDGVIEETLRW
                     NTPTSHVLIRFATEDIEVGDKILPKGEALIVSFAALGRDERQHGPTAGEFDATRTPNRH
                     IAFGHGPHVCPGAALSRLEAGIALPALYEKFPELELAVPASELRNKPIVTQNDLYELPV
                     KLGCPFGHEE"
ORIGIN
        1 ccgcgctcat gggcaaggcc gagcccttct tcgagctgcc gcaggaaggt ggtggcgtac
       61 cccttctccg ggtccttgag gcggctgcgg ccgaggatga gcatggtcag ctcggccaga
      121 tagtcgccgg tgaggacgtc gaggggaccg ccggtgagca tctcgcgcac ggcatcgaag
      181 cggtccccgt agaagccgga ggcgttgccg atgcggagga cgggggcggg ggcgggggtg
      241 gatccggggg ccgggacggg ggcagggccc ggggccgggg cgggagaggg gccgggggcg
      301 gtcaccggtc acctcgtacg gctcgctcgg cgcgtacggc tcgctcggct tgctcgtctc
      361 gtacagcttg ctcggcttgc tcggcgcggg gcgggcggcc gggcccgggc ggtccggcga
      421 aggcctgggc gatggagagc caccggtcgg cctcgctccc ctcggcggtg acggcgaggt
      481 cggagcgatg ggcgcgctgg gtgaccagga ggcagaagtc gaggagcggc ccggtgacgc
      541 gctgggcggc gccttcgggc ccgtacgcga tcaagtcacc gccaggagag cggagttcaa
      601 cccggaactc ctcccccggt gcctcgatcc cccgtaccgc gtaggcgtag ttccgggccc
      661 gtaccccgat ccgggcgaca tgccgcagcc gggcggtggg ggtccgggtg accccgaggg
      721 cgtccgcgat gtcctggccg tgggcccagg tctccatgag ccgggcggtc gccatggacg
      781 ccacactcat cggcggcccg taccagggga tccgggtccc cgccggggcc tcccgcagca
      841 ccgtgtcgag ctgccgccgc ccctcccgcc accgggcgag cagggcgtgc ggggcatggg
      901 cggcgaccag ggcgtcggcg gcctcgtcga cgaaggcctc gggggcggcg agcgccttcg
      961 ccacctcgtc cccgaaccgc tcgggctcgg tggcggcgag cagcgcgacc tcgtcggtcc
     1021 aggcgaggtg ggcgatctgg tgggcgacgg tccacccctc ggcgggcgtc accctccgcc
     1081 aggcctcctc acccaacccc ccgaccagcg cgtcgagttc gccgctctcc tcgcgcagat
     1141 cgtcgaccac cgctgcgaca tcggacacgt gcgctcccct cgggaccggg tgtggtgccc
     1201 aggagcatgg cagcgcgcca ggaaacaatc aagcacgctt gcatgatttc ttgcccgggc
     1261 ccacggcctc gtcgacaccg gggcccggtc acacgcgcca ggaaggcggg acgtacgggc
     1321 cgaagcacca ccctgcccta tgtagggcag ggtggtaagc tggcggcatg ataaagacga
     1381 ccgtgtacct tccggaggat ctggaagtgc ggctcgacgc cgaggcggcc gcgaccggta
     1441 tcagcaaggc cgagctcatc cggcgcggca tcgccctgct cctggagcac gcggagcggc
     1501 cgaagcggag ccgtgagctg ccggtcttcg acagcgggcg gccccgcaca ccggacgaga
     1561 tggacgactc ggtgtacgag cacatcaagg aacgggccgc acgccgttga tcatcgtcgc
     1621 cgacacttcc gccctctacg ccgccttcga tgccgcacag ccggagcact ccgcagcggc
     1681 caggatcctg gaacacgaaa ggctggccat ctcacccctg gtcgtcaccg agctggacca
     1741 cctggtccac cgcgacctgg ggttcccggc cgccctgcag gtgatggagg cgctgaactc
     1801 ccgcatggac gacgggcagt accgcctcgc cgaactcaag ctcgcggatc tccgtaccgc
     1861 ccacgaggtc cggcagaagt acgagggtct gcggctggat ctggccgacg cggtcggggt
     1921 ggtcctggcc gaccgctatc ggaccgaccg gatcttcacc ctggaccagc gggacttccg
     1981 ggccatgacc ccgctcacgc cgggactgga cgccttccgg atcgtgcccg cggactactg
     2041 aggactcccg ctcccggcac acgcgtccac gcccggtcgg cacaggcccg ctgcggctcc
     2101 gccccgtcac ggccggatcg cggccacgca ccggcgcccg tccgccactc cgctgctaat
     2161 ctccgccgat gactgccgaa ccccacctgg tgaacccgca cttcgacggc gaccggctcg
     2221 tcctggagga acaccgcgag gcggaccacg tccgctacct ctttcccggt acggggacgg
     2281 ggcccggtgg ccccctgcgt gcgctcaccc tgaccgaggc cctgcacgca cgcatagggc
     2341 cggccggtac ggcggaggcc gtcctgcggg cctgggcgca gggggccgga ccggcggagg
     2401 cggtggaggt gaaggtggcc gatccggcgg ccgttcctcc tgtacgggtc cgggccgggg
     2461 cgatcgtgat ccgggacggg cacgtcctgc tcatccactt ccgcgagccg gacgaggacg
     2521 gcccgcacta cgagatcccg ggcggcgggg tcgaggcggg cgagacgccc gaggaggccg
     2581 ccgtacggga actccgcgag gagaccggcc tccacgggag cgtcgggcgg aaggtggcgc
     2641 gggtctggaa ggagggccgg cacgagcact acttcctcat gacggccgag ggcagcatcg
     2701 gccccgccga gaccctggac acctacggcg gcaccccggt ctggatcccc gtacccgacc
     2761 tgcccgccct ccccctctgg ccgcgccgcc tctcctggcg catcgagcac tggcaccgca
     2821 cgggctggcc cacacccccg gccgaactgg ccgactcgat caccgacctc caggcgccct
     2881 gtacgtggtg agcggggcgg cggccgatcc ccgggcccgc cgccgcgacg gtcaccccgt
     2941 cttcttccgc ttccgcgccc ccgtctggct gcgtaccgcg cccatgctcg ccccgatgac
     3001 cagggcgatg gcgagggcat ccgtcgtgga gagcgcctgg ttcaggatga ggaagcccgc
     3061 cgcggccgcg atggccggtt ccaggctcat catgacggcg aacgtggagg cgggcaggcg
     3121 gcgcagggcc atgagttcca gggtgtacgg gaggacggag ctgaggaccg ccaccgccgc
     3181 gccgagcgcc agggtcgagg ggacggtgag cttggcgccg gactcccaga tgcccagggg
     3241 cagcgagagg accgccgcca ccaccatcgc cagcgccagc ccgtccgcct gcgggaagcg
     3301 gcggccggtg cgggcgctga agacgatgta cgcggcccac atcgccccgg cccccagggc
     3361 gtacgccgcg ccgaccgggt ccaggcggtc gaagcccccg ccgccgagca ggaccacgcc
     3421 gaccagggcg agccccgccc agaccacgtt gatcaggcgg cgcgaggcga agacggagag
     3481 cgcgagcggg ccgagcacct ccagggtgac ggcgatcccg agcgggatgc ggtccagcgc
     3541 ctggtagaac agcgtgttca tgccgcccat cgccacgccg aaggccagca ccgtgcccca
     3601 gtccgcccgc gagtggcctc gcaccttggg gcggcacacc accagcagga tcagcgcggc
     3661 cgccgccagc cgcagcgtga ccacgcccag cgcccccgcc ttcggcatca gcagcgccgc
     3721 gacggccgag ccgaactgga ccgagaggcc ccccgcgacc accagcgcga ccggcaccag
     3781 cgccgcgccc tttccgggtc cggagtcctt ccgtccggcg gcgtccagag cgggtgtcgc
     3841 ctcgggtacg gcgacggctg ctgcggcggc ggccggctcc gaagcactgc gctggacgtt
     3901 cacgggcggc cttccggaga tacggggagt aggcgggcgg cacgcccacg cccacccacg
     3961 gtagagaccc gcgcgcctcc cgtgaaatga cttctgcgct cccgttatgc tccggacgca
     4021 tgagccgatg ggagcgcacc gcatgagccg tcccgaggac ccgggacacg ccgcgtcccc
     4081 cggccaccac ccgacacccg cgaccggcca gccagaccgc ggccccggac cggcccccgc
     4141 cgctgccgac caggcagacc ccgtctccgg ccaggcagac cgcagccacc acccggcccc
     4201 cgcagcggac caggcatccc ccgcctccgg ccaggcaggc cgcagccccc acccggcccc
     4261 cgccaccggc caagcagccc ccgcccccgg ccagccagcc cccggccacc cctcaccccc
     4321 cgcctcccgg gccgtcgatc tgcgtcatct gcgggccttc ctcgccgtcg ccgaggaggg
     4381 caacgtcacc cgggccgccg cgcacctcgg cctcacccag cccgccgtct cccgcacgct
     4441 cgccgccctc gaacgccacc tgggcctccg gctcgtcgac cggtccaccc atcacctcgc
     4501 cctcaccccc gagggcgtcg ccttccggga caaggccgcc gccgcggtcg ccgccttcga
     4561 cgaggcgctg gacaccgggc ggctgcgcca ctggcccctg cggctcgggc acgcctggtc
     4621 ggccttcggc ccgtacacca caccgctcct gcgcgcctgg cgggagcgcc acccggccac
     4681 cccgctggag ctgctccgga tcgacgaccg cacggccggg ctcacccggg gcgaggtcga
     4741 cgcggcgctg ctgcgcggac cggtccacgc gccggggctc gtcaccgagg tgctgttcac
     4801 cgagggccgg gtggcggcgg tgacggcgga cggcccgctc gcctcccgta cgtcgctgcg
     4861 cctggccgac ctcgtggacg gccccgtcgt cctgaacacc gtctccggca tcacgacccc
     4921 cgagctgtgg ccgccgcaca cccggcccgc cgccaccctc accgtcgcca acaccgacga
     4981 ctggctggcc gccatcgccg ccgggcgcgg cagcggggtc tcggccgcct ccaccgccgc
     5041 catacacccg cacccgggcg tcgcctacgt gccgctcgac gacgccccgg gcgtccccgt
     5101 cctcctcgcc cgccgcgacg gccccggcca ccccgccctg ccgaaactgg ccgccctagc
     5161 ccgggagatc gtcgcgcggg ggtgagcccg aggacgcccc cccggggggc ggaggccggg
     5221 ccggacacat ccacgggtgc tacccggcgt cccggccgaa agcgccgacg aggtcccatg
     5281 caggtgactt ggccgtcagc atccaccggg cgaccggtac acggcacagc ggtgacgtga
     5341 ctcggagatg gagctgttca ggcgtgcagc ctcttcacca tgaccgcgta caccggggag
     5401 tcagcgaatg gccgctgctc acccgccttc tcgtagcccc acgtctcgta caggtcctga
     5461 accttcgggt gcgtcacgtc gaccaggagc accgcgagat cttcgccgcg tccctccagc
     5521 agggcttcgt ggagccgctc cgagatacct tgcctccgcc actgcgggcg caccatgacc
     5581 tcggagactg cgtaggtcgc ggtgtagccg ttgttcggcg cgaacgcagt ggaacgccac
     5641 cactcacggc ccggctggag cggggcgccg tacgcgaagc cggtcggctc gtcgccgtcg
     5701 aaggcgacga cgcaggtgaa gccgtccatt cccgaccagt gatcgacgaa ccacgggaac
     5761 cgctggttga actcgttgtc catagcgtcg gcgtaggcgt cggcgtgcac atcgatcagc
     5821 atctgcttga agccctcggg gaagcttccc tgtccgtagt gccgcaggtc gatcaccttg
     5881 gtcacgttcg actccattca tctcgcatgc ggtctgccca gtcgcgggcg tacgtcgtcg
     5941 acggcgccag ccggaacagg tctcggtgga agtctccgat cagggtgcgc atgcgccccg
     6001 gcagtgggac gccctccatg atcgtgaaga cggtgcccgc ggtcgccgta gcctgctcgg
     6061 gctcgccctg gcggagttgc gccagggcga gctggcaggt ggccagcgcg cggttgcgct
     6121 ggaactccgc tgggatcctg gccagggatc ggtacgccat tgcctcggcc tcggcgggct
     6181 ccccgttgtg gttgaggatg atcgccgcga ggtggttgag ttccgccggc ccgtagaacg
     6241 cggtccatcg aggacgctcg tcctcggccg ccttccggta gttctcctgc gccgcgccca
     6301 aggaccggcg agcggcccgc aggtctccca gcgacgagtg ggcgagcgcg agacggacgc
     6361 ggcccatgga gccgaagaac ggatctcggc gggcagctgg ggaggcgttg gccgcctgag
     6421 ctgccgcgag ctgttccggc cagttcttcc gctggtaggc gagcatggcc atgttgaccc
     6481 acacgcgcat ggccgtgggc gggtcctggg agaggccggc gaacgtggac gactcgtgca
     6541 ggtacgtccg ggccttgtcc aggtcacgta ggtcgatgca cgaccaggcg gcgacggtgg
     6601 tgaactcggc cgcgagcgcg tacagggcac ggcgtacacg ttcgctggcg ttccgctgct
     6661 gaagctccag caccttggcg cgagcttcga gggctgcggc cgccagggag gcgtgcccgc
     6721 cctggcgatc gtcggcctcc acgagctggt tcatgccggc cgaggctcgg gccacgtccg
     6781 tcatgccgac cgaccgacgt tgcttgacca cgggaacggc tgcggccgcc gtcccggtgg
     6841 tggaagcgat gaagtcgcga cgccgcacgg ggccctccgg gggatgttgc atggagctgg
     6901 gtgcgctgaa ccctaagtcc gccacggggc agccgaacac acgctcaagt gcggcgcaag
     6961 tgcgtccgat tggacgtcgg cttgatccgt tgagcaggtt gcgcaccgtc cgggaggaga
     7021 tgtcgccagg ccgaccggtg atctcctgca gcgcggcgtt caggcgtgcc gccaactcct
     7081 cctgcgtcag accgagttgc tcaagtcggt cctgaagaac gagatttccc cccatgcacc
     7141 gaacgtaacg ccaccgtcac gctgacacct ggagctcggg taatggaaac gtaaagtctt
     7201 ccggttggtg ggcgtgcacg gatcctggac tcttcctgtt gcgctgcgct cgttgctcgt
     7261 tgactggtca tcggtcgcca agccgggttc ggtgcggcgg cacggaggaa agcccggtcc
     7321 tgccttgctt gtacggaccg ggaaccccag ccggagggaa agacctcgtg accatgaccg
     7381 tcgctcaacc gaatgcgatc gactccccgg gttacgccgc agaggtgccc tgcgtacgtg
     7441 agtccgtgag cctcgcccgc gctttcgtct cccaggtact ggcggtctgg ggcatggacg
     7501 acgacgtgac cggctgggga aaggccatcg tcactgaact gctggccaac gccgtcgagc
     7561 acaccgagac ccctgtgtcg cgcatccaca tcgcgcgtcc gagcaacggt gccgtccgca
     7621 tcggagtctc cgaccgctcg cacggcgctc cccgtctgaa gacggccgac ctgaacgctg
     7681 agagcggccg gggtctgagt ctggtcgcgg cgatgagttc gcagtggggc tacgacatgc
     7741 actcgtgggg caaggacacc tgggctgtgg tcgagactcc ggtggggaga gagcggtgag
     7801 caccgcagtg gctccgaaac ctccagccca ggagtggacg ccaccgctcg acgcggacgg
     7861 tttacggctc gtgctggagc ggttccgggc gtgggacccc ctcgacatcg aggaggtctt
     7921 cgacgacctc gacgcggcga tcggcagtca gccgccacct gttgcatcgg ctgtcgccct
     7981 gctcggccgc ctccgcaggc acctgaagca gctcagcaac atcacggtgg ctgacgacaa
     8041 cttcccgccc agcgccgaga tgacccgcct tgtcgagcga ggagttcctc tgctggagga
     8101 gcccactccg gctggctatc ggcaggccgt cggactcgcc cgccgtctcg ccttcgtgac
     8161 cgctgacctg atcgaagtgt tgatcgaggc tcgctacgtc aaggagatcg agtgacgcac
     8221 gccccttgcc acccgcgagc cacccagcgg gctggtcgac acgaaccggc ccgccgggca
     8281 gccctccgcg ggcgtggacc tcccagctcg ccgtccagcg cggccctgtc ggtcacccga
     8341 cgagaaccga gcgcgctctc ccctggacta cccgactcat ccggcacgcg accgccggcc
     8401 tgctcccccg tacgcacgac tgaaggaagt ccatgacgaa cacgaccgtc gagcccgacg
     8461 aagcgacccg tctccggaac aaggtggtgg acgagttgcg cgcaggcggc gacatctcct
     8521 cctcggagat cgaagccgtc atgcgcaagg tgcctcggca cgcgttcatt cccgacaccc
     8581 cgctggacaa ggcgtacgac acgtacgcgg cggtgatcac caagacggac gagcacggtg
     8641 tgcagctcag ctccgtctcc gccccgcaga tccaggcgat gatgctggag caggcccagg
     8701 tgaagcccgg catgcgcgtg ttggagatcg gttcgggcgg gctgaacgcc gcctacctcg
     8761 ccgagctcgt gggtgaggac ggcgacgtcg tcaccgtgga catcgacccc gtcgtcaccg
     8821 agcgggcgca acggctcctg gacgagcacg gctacggcag agtgcgtgtc gtcaccgccg
     8881 acgccgccga gcccattccg gagctcggcg aggtcgacgt cgtcatggtg actgccggag
     8941 cctgggacat cgctccggcg tggaccgcgc agctcaagca gggcggtcgg cttgtggtgc
     9001 cgctgcggat gcgtggcctg acccggtcgg tcgcctttac ccagatcacg ggcgaacacg
     9061 gcccgtacct ggagagcgtg tcggcgctca tctgcggctt cgtcccgatg cagggctcga
     9121 cagcccaccg ggaagaactt cttctcgtca acggcacacc ggagatcggg ctgaagttcg
     9181 acgacggact accggccgac ccacaccgac tggacaacgc ggtcacgttc ccgcgccacg
     9241 agctgtggac aggcgtcgtc atcggcctct cggaactcgt cgacaccctc cagatggcca
     9301 tggccatcag cctgcccggc ttctgcacga tggccgtcga cgaggacctg gacacgggcc
     9361 tggtcgcccc cgtgaacaag cggttcgccc tcgccgccgt cgaggacgac accttcgcct
     9421 atctcgtcac ccgccgtacc gaggacaaca agcacatcga atacggcgtg cacgccctcg
     9481 gcccgaacgc ggagcagttc gccgaccagg tcgccgacgt gctccgtgac tgggaggcca
     9541 gccggcgcgg gggccccagc ccggtcatcc gggtctatcc ggtcaacacc tctgatgacc
     9601 agatcccggc cggccgggtc atcgacaagg tgcacagccg ggtctcgctc tcctggccct
     9661 cggcgtaacg ccggaagcca ggttgttcca caccatccgg acaccaagaa gaaaggcacg
     9721 gacatgacga gcgccactct gtcccctccc gccccgctgg cgggcctgga cgacgacttc
     9781 gcacccctgg acgtgaaggt cgtcatcgcc gagcacgcgt acggcaagct catgtgctcc
     9841 acgggcgacg gctgcggcac cacctgcgcg accggcgcct ccgcctgcgg ctccttcacg
     9901 gaggacccgg cctgatccag gccgttccct gccggtgggc cgagcaaatc gctccgctcg
     9961 gcccaccggc tcctcacccg ccccgccaga cggagggccc atggtttccc gagcagtcgc
    10021 cgactaccga tggcagggcg ccgccatgct gcgcgccacc accagcaccg gaccggcaga
    10081 catcccccgc actctcgacc tggacaacgt ggccgtcact cgcgggtggc tgaaccgcgt
    10141 ctgggaaggc gatggcttcc gcaacgcgct ggagctggcc acccccgtcc tgtccgacgc
    10201 cgtcgaagca gtcgtccaag gccggcagtc cgagccccgt cacgtccgcc gcaccgcggt
    10261 atcgacggtc tcctacctct tgcggtggca acaccggccg atcccgctgg gcctgttcgc
    10321 cggcaccgct ccggtgacgg tcgggcccag ggcaagcgcg cggtggcgcg acaagcaccg
    10381 cgtgctgatc cggccggact ccgaatgggt caccgacatg gtcctccggc tccagcgcat
    10441 ccccgcgtta ctggcgcggc tcccgctcgt cgccaacaac gcagcccgca cgcggggcga
    10501 tcggctcgtg gcgccgggcc cgccctccga cgggcacgcc gtcctgctgg ccccggtcga
    10561 gatatccgtc cggaatgccc ggccggtggc cgccgccatg gacgccgccc gctcgcccat
    10621 cccttacggc gccttgtgcg gccacctgcg cgacagcttc ccgcaggcca caccggagca
    10681 gatcgacggg cttctcaccg gcctggtcga gcagcagttc ctcatcacca gcctgtgggc
    10741 acccatgacc accgtggacc ccctccagca cctgtgccac gaactggaac agcacgacgc
    10801 ggacagcatc cccgacgtgc gggacctggt ccacaagctg tacgcgctgc gcgacgaggt
    10861 atccgcccac cagccgacac tctccgacat cagcgtgagc gccctcgcca cacggatgcg
    10921 cgccctcacc gccgtcaccc cgacaccgtt gctcattgac accgccctcg actgcgagac
    10981 ccagctcccg cagaccgtga tcgcggaagc gcaggcagcc gtgtcagccc tctaccggac
    11041 caccccacag ccctacggct atcagcactg gcgcgactac caccgccggt ttcgggcccg
    11101 gtacggcgtc ggcgccctgg tgccggtgat ggacctggtc gccgacagcg gcctcgggct
    11161 gcccgccgga tacgtgggct ccgaacgcgg agcctccctg aaggtgcgca ccgaccgcga
    11221 cgagctgctg ctctcgctga tgcagcaagt cctcctcgac ggccgcgacg aactgcggct
    11281 gacggacgac atggtccatg ccctggagaa ggccgccgga acggacgagc ggctgttcgt
    11341 gccccgagtg gaggccgcct tcgagatcca cgcccccagc acccgggcgc tgtccagcgg
    11401 cacgttcgac ctcctgctca cggcggtgcc ccgcccaggc agcagcatgg cgggccggtt
    11461 cgcccacgtc ctgccgcccg agcaccaaga cgccctcgcc accagctatc gcggggcacc
    11521 ggaccgcctc gcggcgcagc tcgtgttccc accgcgtcgg caccgcaacg agaacgtcac
    11581 ccgcacatcg cgactgctgc cgcacatcat cgagctctcc ggccaccagg agctcgacga
    11641 gacaacgatc cggctcgccg acatcgccgt aaccgccgac ccgcgcagtt tccatctcgt
    11701 gcagctctcc accggccggc ccatcgacgt gcgggtcctg cacgccctgg aaggcggcac
    11761 ccagaccccg ccgctggccc ggttcctgac agaagtggcc aacggacggt acgccgccta
    11821 caagccgttc gacttcggcg ccggttctcg gctcccgtac ctccctcggg tccgctaccg
    11881 ccgtaccatc ctcacgcagg cccgatggct gctgatggcg gaagacctgc ccgcccggaa
    11941 agccccgagg aaggagtggg aggacgcctt cactgcctgg cgggaccggc tgcgggtccc
    12001 gatgcaggtc gccgtcatcg agtacgacca gcgcctcccg ctcgacctgt cccacccggt
    12061 ccacctccgg gtcctgcgcg cccacctcga caacgcccgg cgcgtggaac tgcgcgaggt
    12121 accggacgca gacgcccacg gctggatcgg acgggcacac gagatctggc tctcgctgga
    12181 ccgttccgat ccggacaccc cgtacgtgcc ccggccacgc tccactacgt cgccgggcgc
    12241 ccagcggcac ctgccgggcg gcggcaacgt tcttcacgca cagctccacg cccatccgcg
    12301 ccgctacgac gagattctga gccaccacgt cccccacctg ctctccgcat tcggggagga
    12361 gccgccgact tggtggttca cccgccaccg ggagatggcc cggccggacg ccgaccagca
    12421 cctcgacctc accctgctcc tgtcgccgga ctcgtacgga gtcggcgcac agcacgtccg
    12481 cgcctgggcc gacagcctgc acgcgatggg gctcgcgtcc ggactcgccc tggccacgta
    12541 ccagccgcag accggacgct tcggccacgg gccggccatg gacgccgcgc accaggtatt
    12601 cgccgcggac tctgccgccg cccttgcgca gatccagctc gccgagcgca ccgatgccct
    12661 cgccccacag gccctcgccg ccgccagcgc cctgcacctc gtcactcccc tggcaccgaa
    12721 cgctgcggcg gccgaagagt ggttggtggg caacctcccc cagggcaccg gacggttgga
    12781 ccggaccctg cgcggccagg tgctcgaact caccgggccg aacggtgcct ctgcgctcgc
    12841 gtccctcccc gggggcaggc aggtcgccga agcgtggcga gcccgcgccg ccgcagtgga
    12901 cttctaccgg accgcattgg tcagtgaacg tcatccgctc gatgtcgccc gctcgctgct
    12961 gcaccagcac cacgtccgag ctcttggcgt cgatccgcgc accgaggaga cgacgatccg
    13021 actcgtgcga acagccgccc tccagcaccg gatggcggac cgatgacgac gccggcaacc
    13081 gccgccacga caatcttggg gcagtacaca gctgatttgg ctgagcctcc tgccccgccc
    13141 ccggaggagc cctgggcggt gcagtcgctc gccgacggcg ctgccggaat cagcctgcta
    13201 cacatggaga tcgccagcag gtacggcggc tcctggcgtt ccgcccaccg gtggatcacg
    13261 agtgcggcct ccggccccat cagcgcggcc gaccaggcgg gcctgttcct cggcgccccg
    13321 gccgtcggct tcgtcctcac cgccgttccc ccggcgtacc ggcatctgta tgcctcggcg
    13381 cgcacgaccc tgcaccagca catcaccggc ctcgcccacc gtcgcgtgga cgccgcgctc
    13441 gcccgcatcg gcaggggaga cctgccgacc ttcgcggagt acgacctctt ctacggcctc
    13501 accgggatcg gcgcctacct cctgcgcacc gagcccgagg gcccagctct ggagaggatc
    13561 ttgcagtacc tcgtcgccct tacccggccg ctcgccgctg acgggcgcgg gctgccaggc
    13621 tggtgggtcc gccatgaccc ggcgcgcggc gagtcgcccc acttcccggg cgggcacggc
    13681 aacttcggcg cggcccacgg catcacaggc ccgctcctcc tcctggccca ggccatgcgc
    13741 cgaggcgtca ccgtccatgg ccaccaggac gccatgttca ccatctgcgc ccacctcgac
    13801 gcctggtgtc agcacggcga ttccggcccg tggtggccag agcacatctc ccggcacgac
    13861 ctcgaccgcg gtcagcctca tcacgacgcc cccgcccgtc cgagctggtg ctacggcacg
    13921 gcaggcatcg cacgggcgga ccagctcgcc gggatcgccc tgcgctcacc catgcttcag
    13981 aagttctacg aggacgccct gtaccgagcc ttgtccgatc ccgctcgact aaccctgatc
    14041 acagacaacg gcctctgcca cggatgggcg ggcatctacc agaccgctca ccgctcaccg
    14101 cgcagccgca gacgcggtcg acgcacggct gcgcatcctc ccggaccgtc tcggtcacgt
    14161 cctcaccgcc tccggccagc ccggcacctc ctcgactccc ggcctgatca acggcgcggc
    14221 cggcaccgca ctcgccctca ccacgttcgc ctcgaagcag gcaccgagca ctggatggga
    14281 cgcatgtctc ttgatcaact gactcagcaa accgagccga acccgacgca gcacgccgtg
    14341 ctcgccgtcc tgaccggcct gccgctcacc gatgcagcgc gccagtaccg gatggacccc
    14401 gtggtcctct ccgacgcagt cgcggtctac aaccaggccg gccgggaagc cctgctccat
    14461 cacgcggcca ccaccgactg gtggcagacg tacctccact tcacgggctg gtcgaacgct
    14521 gacggcacct tcgccgcgca tgtcctgccc atcctgcgcg cggcggaagc cgctggcgcg
    14581 gtcgacggct ggtggtacac gagaaagcac ccctgctggc ggctacgtct ccggatccag
    14641 tccgtaaacg atgccaagct gaccatcagg gacggcttcg accgcctcgt atccgaagga
    14701 cgccttcagc gctggtggcc cggcatctac gaaccggaga cgcctgcgtt cggcggaatg
    14761 accagcatga cggccgcgca cgctctgttc gtcaccgaca gccgagagat ccagcagctg
    14821 cgcctgcgcg acgatctcgc catcgggccc agggagttat ccgtcctgct gtgcaccatc
    14881 atgatgcgcg ccgcacggtt ggagtggtac gagcagggcg atgtctggga ccgcgtcatc
    14941 acgacggaac accgctcggc cgtcagcgac gtaccgccgg aacagctgaa cgcccgagcc
    15001 caggagatcc ggcacctgct tctcgccgac agcgacaccc tgctgcgccc cggaggcccg
    15061 ctggaacccg tcgacgagtg ggtcgcagca ttccacagcg tcggccagac cctcgccaac
    15121 ggcgtccagg acggaactct cgaccgaggg ctacgacagg tgctcagcta ccacgtgatc
    15181 ttccactgga atcgacttgg gctgtccctg cgcgggcaaa gcatcctggc ccgggcggcc
    15241 agaggggcag ttctgcagga cgagtcccct tggtagagac agggcccgtc acgatcctca
    15301 tcgtcgaggg caccaccgtc cggggtcgct ggcacagtgt tctcctacgc cattgcgtca
    15361 gacgcaggta gtccgccagg gacctgtggg tggcctcggg ggtccggagg gggccatcac
    15421 caccgcgtcg gtgaaagcgg ggcgaacctt gcggtcacac ctcggggcga gaccgtcgtc
    15481 cggatggtgc tggaccggat atgagcatcg ctccggacag ggccgcggcg aggaccgccc
    15541 ctctcctccg ccgctttcca ccgtcttcca tgacgttccc ccttgcgaac cacgacgacc
    15601 acggcaaacc cgtcgatgct agcgcccggc cccttcccct cttacgtggg cggcgatggt
    15661 ccgggcgcac tccagggatt ccgtacgggt ggtgtcgacc tccaggtcgt agaccacgcc
    15721 ccggtggacg ctctccgcct gtgccgccgc catgccgacg gtacggtcgc cccgggcgat
    15781 ctcccgcccc gccgccacct cgcccgcgca ccggaccccg acccacaaca ccccgagccc
    15841 gcccagccgt tcgctccacc gccgctggcc cgccgccccg ctgaggaaca cctcgtcgac
    15901 gatgatccgg gcgcccgcgc gggccatcgc ggcgaccccc tcggtccagg cgtcctccag
    15961 gtcccggaac tccgacccga tgctcaccga gccgtccggg ccgaacacga tccccgtctc
    16021 cgcggcctgg agggcggcgg gcatcgcctc gaccatcgtg tcggtgccga gcgcgagcca
    16081 cgggtccggc aggagggcct ggaggcaccg gacgatcccg gacttgccgg agctggaacc
    16141 accgttgagc acgatcactc gcgtctgcgc acgcgtcgga ttcttcacgc gcgccaccgt
    16201 acaagcgccc ccacgctcac cgccgcgatg gccgttcgcc gtcaccgccc tccagccctt
    16261 ccgcgatcac ctccgccagg tggcgggccc ggcgtccggc cggtgggccg agccggtcca
    16321 gttgcgtacg gcaggagaag ccgtccgcca gcagctccgc acccggttcc gattcccgta
    16381 cggcagggag cagttgctcc tctgcacacg caacggacac ctcccagtgg cccttctcga
    16441 agccgaagtt cccggccaga ccgcagcacc cgccgctgag ttcgccggtc agccccagcc
    16501 gctcccgcag ccgccgctcc gccgcgtccc cgaggaccgc gtgctggtgg cagtgggtct
    16561 ggccgacgac cgggcggtcc aggcggggcg gggtccagtc gggggcgtac tcctccaggt
    16621 actgggccaa ggtccgtacc cgtgcggcca gttcggcggc cctcgggtcg tcggggagga
    16681 gttcgggcag gtcggtacgg agggtggcgg cgcagctcgg ttcgaggacg gccaccgggt
    16741 ggccggggag cggggcgaac cggtccaggg tgcggcgcat cacccggcgg gcggcgtcca
    16801 gttggccggt cgacacgtac gtgagcccgc agcagacccc ggccggcggc gggagcaccg
    16861 tacggcccgt cgcctcctcc agtacccgta cggccgcccg gcccacctgc ggggtcaggt
    16921 actcggtgaa ggtgtccgcc cagaggtgga ccacccggtc gggggagagg acgcgcgtta
    16981 ccttgccctc tccctcgccc tcgcccggcc cctccccctg atgtccgcgc agccagcggc
    17041 tgtacgtctc cgtcgccagc accgggatcg tccgctcggg cgcgatcccc gccagccgtt
    17101 tcgcgagggc cgccaacggg cgtacgcgcg caagggcgtt gagcgggcgg gcgaacgggg
    17161 cggccaggcg aagccactgc gggaggcggc ccagggcgta gtgggcggcg gggcggatcc
    17221 ggccccggta gtggtggtgc aggaactccg ccttgtacgt ggccatgtcg acgccgaccg
    17281 ggcagtcgct gcggcacccc ttgcaggaga ggcagaggtc gagcgcatcc cgtacctccg
    17341 tgctccgcca gccgtccgtg atcacctcgc ccgcgagcat ctcgtgcagc agccgggccc
    17401 tcccccgggt ggagtgctcc tcatcgccgg tcacccggaa ggacgggcac atcacgcccg
    17461 ctcccccgct cggcgcctcc gccgtacggc acttggcgac gccgacgcac cgccgtaccg
    17521 cccccgcgaa gtcgccgccg tcctgcggat agccgaaggc cacgtccacc gggcgcttcg
    17581 ggagcacctc gaagcggagg ttcgtgtcca gcggggccgg gcgggcgagg atgccggggt
    17641 tcaggccgcc gtcggggtcc cagagatcct tgaacgcgcc gaagagggcg acgagttcgt
    17701 ccccgtacat ccgggggagc agctccgcgc gggcctggcc gtcgccgtgc tcgccgctga
    17761 gggagccgcc gtgcgcgacg acgaggtccg ccaactcctc ggagaaggcg cggaatcggg
    17821 cgatcccggg cggggtcagc aggtcgaagt cgatgcgtac gtggatgcag ccctcgccga
    17881 agtggccgta cggcgttccg cgcagggcgt gctgggtcag cagggcccgg aagtcgcgga
    17941 ggtaggggcc gagccgggcg ggcgggaccg cgcagtcctc ccagccgggc caggcctcac
    18001 tgccgtcggg catccgggtc gcggtcccgg cggcgtcctc gcggatgcgc cacagggccc
    18061 gctgcccggc cgggtcggtg acgacggtcc cgtccaccgc gtcggcggag cgcaggacgc
    18121 gctcggcctg ggcgcgggcc tcggccgggg tggcgccgcc cgtctcgacg aagagccagg
    18181 cggccccgcg cggcagcccg gccggttcgc gtacgaggtc ggcggccatg ccctcgacgg
    18241 tgagcgggcc gtacgggagg aggcccgggg cggcctcggc ggcggccgcc tcgtcggcgt
    18301 acccgaggac ggccagggcg cgggcgcgcg gggtctccac caggcgcacg gtcgcctcgg
    18361 tgaccacggc gagggtgccc tcgctgccgc agaacgcccg gaccgggtcg gggccgccgg
    18421 ggtgctcggg gagcagggcg tcgagcgcgt agccggagat gcggcggggg aggtcggggt
    18481 agccggtgcg gaggagggcg aggtgggcgc cgatcagttc gcgtacgccg tgggggccgt
    18541 gggccgacgt cccgcgtacg ccgtcggggc ccatgccccg ggtctgttcc agccgcagcg
    18601 cctcgccccc gtaccggacc acctccagcg cccgcacgtt gtccgccgtg gtgccccagg
    18661 ccaccgagtg cgcgccgcac gagttgttgc cgatcatgcc gccgagggtg cagcggctgt
    18721 gggtggacgg gtcggggccg aaggtcaggc cgtacggggc ggcggccgcc cggaggtcgt
    18781 ccaggaccac gccgggctgg acggtggcgg tgcgggcggc cgggtccacg tcgaggatcg
    18841 cgttcaggtg gcgggtgagg tcgagcacca ggccggtgcc ggtggcctgg cccgcgatgg
    18901 aggtgccgcc gccgcgcggg acgacgggga ccccgtactc ctggcagacc gtcagcgccg
    18961 ccgcgatgtc gtcggcgtcg cgcggggcga ggacgccgag ggggacgcgg cggtagttgg
    19021 aggcgtccat cgtcgtcagg gcccgggcgg tggcgccgaa gtcggtcccg ccgcgcacgg
    19081 cggtgcggag cgcggcggcg aagtcggccg gcggtgccgg gggtccggta tgcgggcgat
    19141 gcagttcggc catggcctca ggatgccgtc ggtacagatg aactcttggg atgcggactg
    19201 acaaaaacgc tcaagcttca caaaaaagcc cacaagatct tcccaaacag accgtcaagt
    19261 ctcctatagt gaccaagact tgagcaggaa ctatcagctc cagttgtgca tgatcgtcca
    19321 ctcccgtggt gaactgtccg gattccaccg gtgcggtttc gcctcgtccc acgtcccgca
    19381 ccgtccgcca ccgaggactc cgattgcgcc cctcattcag gcccaccgca ctcgccctgc
    19441 tgatctcggc agccgtcacc ggcgcgctga ccctgtgggc cgtggccgcg gcccccgatg
    19501 cggtacggac cccgctggcc tggggcgcgg ccgcggccgc cgtcctgctg agcgtctgcg
    19561 tggccgtcac cgtccacacc ctggggaccg tccgcgccct gcgcgcccag cgggccgccg
    19621 acaaccagcg gttcaccgcc gagacctcgc ggctggtctc cgcctccgcc gccgaggccc
    19681 agcgcttcac cgccgagacg gcccggatca aggccgccgc ctccgccgag accgcccggg
    19741 tgaccgccga ggcccgcgcc gagaacgagc ggatcgccgc cgaggccgcc gccgagaagg
    19801 cccggctctc cgtcaccgtg gaccggctca ccgcccgcgc cacccgcgcc gagaccgaac
    19861 gctccgccgc cgtcgcggcc tgcgccaacg cggccgggcg gatgcaggcc ctggccacca
    19921 gcatgctggc cgacctgcgg gagatggagc accggcacac cgacgagtcc gtcctcgggg
    19981 acctgctcca cctggaccac cgcaccgccc aggcgggccg gctcgcggac tccatcgccg
    20041 tactgaccgg ggcgcgctcc gggcggcgct gggccaagcc gatcgtcatg gagtcgatcc
    20101 tgcgcggcgc gatgggccgc atcggctcct accagcgcgt ccgcctccac tccaccagcg
    20161 atgtggcgat cgccgggcac gcggccgagg gcgtcatgca cgcgctggcc gaactcctcg
    20221 acaacgcggc caacttctcg ccgcccaccg ccgaggtgca tgtgtacgtg gaggaggtcc
    20281 cggcgggcat cgtcatcacc gtcgaggaca gcgggctcgt gatgagcgag gtgcagctgc
    20341 gccgcgccga gcaggccgtc tccgccgacc accagaacct caccaacctc tccggtaccc
    20401 ggctcggact ggccgtcgtc ggccggctgg cccgtaagca cggcctgacc gtctccttcc
    20461 ggccctccgc gcggggcggc accggcgcgc tgatgatgct gccccaggac ctgatctccc
    20521 ggaccgccgc accggccctc ccggaccggg caccggccgc gacccccgcc gccgcactcc
    20581 cggccgccac gccttcggcc gcacccgtga ccgcgcccac tcccgcgacc gcgcccgccg
    20641 agcccgagcc gtcccacgcg tcggccgcgg gcgcgggcct ctccgggacc gtgcccgcgg
    20701 cccggtccac cgccgagaac caggcctccg acggctccac gcccctgacc ccggcggcgg
    20761 agccgcagcg cacggagtcg gagtccgaat ccaccggcag cgtccccgcg ttcggcgaga
    20821 gcggcctgcc caagcgccgc cggggccgca cgctggccgc cgccgaagcc cgtaacggca
    20881 acgccgccca cggcggagcc gaaacccccc aggcccgtac caccgacgcg aaggtccagg
    20941 ctgcgcgctt cagcaccttc agccgggcgg tacgtgccaa ctcccagcac ccggaaggca
    21001 acacccgatg accgcgacca ccgacgagaa gctcaactgg ctgctggagg ggctgctcga
    21061 ccgcaccccc ggcacccgcc acgccctcgt cctgtcccgc gacggcctca agctgtgccg
    21121 cacccccgaa ctctcggtcg accaggccga ccagctcgcc gcgatctccg ccgggatcca
    21181 gagcctctcg cacggcgcgt ccatcgagtt cggtgacggc accggcggcg tacgctccgc
    21241 gatggccgag ttctacggcg gggtgctgtt catcgtcgag gcgggtgcgg gcgcccacct
    21301 cgcggtcgtc gccgacgagg actccgacgt gggcctggtc ggccacaaca tgagcgagct
    21361 ggtcgaacag ctcggtgagc acctcgtcgc cccgccgcgc acccccgtgg cagagagttc
    21421 ggccgtatga cgacggcgcc ccgcccgcgc ccgggccgcg acgacgatcc ggaccggctg
    21481 tacaccctca ccgggggacg cagccgctcc gactcggccg ccttcgatct ggtgaccctc
    21541 gtcgtcgcgg agtgcgaccc ggcccccggc atgcagtcgg agcacgtggc gatcctgcgg
    21601 atgtgccaga gcccgaccgc cgtcgtcgag atctccgcga ccctgaacct gccggtcagc
    21661 atcgtccgca tcatgctgtg cgacctgctg gacaccggcc gggtcagcgc ccgccacccc
    21721 cgtaccgccc gtgtcgcgga ccggctcccc gaccccgaca tcctggaaca ggtgctcgtt
    21781 ggactccgca acctctgacc gcgccaccct gagcgacacc gccgacaacg gactcaagat
    21841 cgttgtcgtc ggcggcttcg gcgtcggcaa gaccaccatg gtccgatccg tgagcgagat
    21901 ccgtccgctc aacacggagg agacgatgac ccgcgcgggc gaggccgtcg accacctcga
    21961 cggcgtccag gccaagacgt ccaccaccgt ggcgttcgac ttcggccgca tcacgctcga
    22021 cgcccgctcg gtgctgtacc tcttcggcgc gcccggacag gagcggttct ggttcctgtg
    22081 ggaccggctc ttctccggca cgctcggcgc ggtcgtcctc gtcgacaccc gccgactggc
    22141 cgactcctgg tacgccatcg accgcctgga gcaccacggc acgccgttca tcgtggcgtg
    22201 caacgacttc ggcgggccgc tccacagcga gcagcagatc cgcgaggccc tggacctcgc
    22261 ggacgacgta ccgctggtgg agtgcgacgc gcgcgaccgg tcctccagca agtacgtgct
    22321 catcacgctc gtcgagcacc tcgccgcgct ctccgccgcc cggctgcggg cccccgatgc
    22381 gaccgtgccc ggagccgacg tgcccggagc ggccgtaccc gcgggagccc tggccggccc
    22441 gaccccggag cccgccccgt gacgacgacc tcagacacca ccggaaccac cggaccgacg
    22501 gcttccgacc cggcgaccgc cgcgcagacc ggaaccacgg cctccgggtc cacggccacc
    22561 ggaacgacgg ccgccaccgg aacgaccgga ccggccgcct ccggggcccc cgggcccgca
    22621 gcggcccccg ggtccgcagc gcccacccgg tccgccccct ccggctgccc cgtcgcccac
    22681 ggctccgtcc cgctctccgg cccccgcttc cagagcgacc ccgtccagct ctaccgggac
    22741 atgcggcgcg accacggcgc cgtcgccccc gtcgtgctcg acggcgacgt gcccgcctgg
    22801 ctcgtcctcg gctaccgcga gctgcaccag gtcaccggcg acccggtcct tttcagccgc
    22861 gactccgagc tgtggaacca gtgggaccgc atccccgacg actggccgct gctgccgatg
    22921 atcgggcgca ggcagaactc gatcctctac acggtcgggg agcgccacag cgtccgggcc
    22981 atgatgatca gcaacgcgct ggagggcgtc gacccgttct ccctgaagcg gtacgcggag
    23041 gagttcgcgg acgagctgat cgaccggttc tgcaccaagg gcgcggtcga catcatcgcg
    23101 gagtacacca agctgctgcc ggcactcgtg ctggccagga tctacggcta cccggaagag
    23161 gtcatccgcc ccctggtcgg atcgatcaac gacatcacgg acgggctgga tcgggccatc
    23221 gccgggtccc agcacctggg catggccacc ttccaactgc tggccgagaa gcacgccgag
    23281 ccgggcgacg acgtcgtcag ccgcatgatc gcggacgagg gcgggttcac cgacgaggag
    23341 atcgtccagg acctgctggt catgatcgtc gccggccacc agccgaccgc cgactggatg
    23401 ggcaactcgc tgcgcctgat gctcaccgac gagcggttcg ccgcctcgct ctcgggcggc
    23461 cggcacagcg tggcggaggc catgaacgag gtgctctggg aggacacccc gacccagaac
    23521 gtggcgggcc ggtgggcctc ccgcgacacc cacctcggcg ggcgccacgt ccgcgccggt
    23581 gacctgctgc tgctggggat cgccgccgcc aacggcgacc cgcaggtgcg gacccacgcc
    23641 tcggcgctga ccggcggcaa caacgcgttc ctctccttcg gccacggcga gcaccgctgc
    23701 ccgttcccgg cccaggagac cgccgaggtc atcgcccgta ccggcatcga ggtcctgctc
    23761 gaccggctgc cggacatgga cctcgccgtc cccgccgagc agctcacccg ccgcccctcc
    23821 ccatggctgc gcggactcac cgacctgccg gtcctcttca cgcccacgcc cgccctgggc
    23881 agacccgcca gcttcggagg ccccgcatga cccgcatcgc gctcgacccg ttcgtcagag
    23941 acctcgacgg cgagagcgcc gcgctgcggg ccgccgggcc gctggcggag gtggagctgc
    24001 cgggcggtgt acacgtgtat gcggtcacgc accacgcgga ggcccgggcg ctgctcaccg
    24061 acagccgggt ggtcaaggac atcaacgtct ggaacgcctg gcggcgcggc gagataccca
    24121 tggactggcc gctgatcggc ctggccaacc caggacgctc gatgctcacg gtggacgggg
    24181 ccgaccaccg ccggctccgt acgctggtgg cacaggcgct caccgtacgc cgggtggagc
    24241 ggctgcggga gggcatcgag gcgctgacga acgcgagcct ggagaagctg gccgcccacc
    24301 cggccgggga accggtggac ctgaaggcgg agttcgcgta cccgctcccg atgaacgtga
    24361 tcagcgagct gatgggcgtg gacgcggcgg accacccgcg gctgaaggag ctgttcgaga
    24421 agttcttctc gacgcagacc ccgccgcagg agttcgtcca gctgatggcc gacctcgaca
    24481 ccctcttccg gaggatcatc gaggacaagc gggccaaccc cggcgacgac ctcaccagcg
    24541 cgctgatcgc ggcgtccgag aacggcgacc acctcaccga cgaggagatc ctcaacaccc
    24601 tgcaactgat catcgccgcc gggcacgaga ccacgatcag cctcatcgtc aatgcggtga
    24661 aggcgctcca gacccacccc gagcagcgca agaaggtcct cgacggggag atcggctggg
    24721 acggcgtgat cgaggagacg ctccgctgga acaccccgac ctcgcacgtc ctgatccgct
    24781 tcgcgacgga ggacatcgag gtgggcgaca agatcctgcc gaagggcgag gcactgatcg
    24841 tctcgttcgc cgccctgggc cgggacgaac ggcagcacgg cccgacggcg ggcgagttcg
    24901 acgccacccg cacccccaac cgccacatcg ccttcggcca cggcccgcac gtctgccccg
    24961 gcgcggccct gtcccgcctg gaggcgggca tagcgctccc ggcgctctac gagaagttcc
    25021 cggaactgga gctggcggtc ccggcgtccg aactgcgcaa caagccgatc gtgacgcaga
    25081 acgacctgta cgagctgccg gtgaagctgg gctgcccctt cggccacgag gagtagcccc
    25141 tcctccgtgt cgggtccacg agccggagcg gacacgacgg gccggggtcc acgagccgga
    25201 gcgtgcgtct caccggacgg acacggttgc gacgccgtgc cgccgaggga ctacgctccg
    25261 actcgtggcc gacatc
//
