LOCUS       NZ_CP012382            37148 bp    DNA     linear   CON 26-APR-2024
DEFINITION  Streptomyces ambofaciens ATCC 23877 chromosome, complete genome.
ACCESSION   NZ_CP012382
VERSION     NZ_CP012382.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces ambofaciens ATCC 23877
  ORGANISM  Streptomyces ambofaciens ATCC 23877
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303940)
  AUTHORS   Thibessard,A., Haas,D., Gerbaud,C., Aigle,B., Lautru,S.,
            Pernodet,J.-L. and Leblond,P.
  TITLE     Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the
            spiramycin producer
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303940)
  AUTHORS   Thibessard,A., Haas,D., Gerbaud,C., Aigle,B., Lautru,S.,
            Pernodet,J.-L. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUL-2015) Faculte des Sciences et Technologies,
            Universite de Lorraine, Boulevard des Aiguillettes, Vandoeuvre les
            Nancy F-54506, France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC workbench v. 7.0.3
            Genome Coverage                   :: 114
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001267885.1-RS_2024_04_26
            Annotation Date                   :: 04/26/2024 02:57:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,510
            CDSs (total)                      :: 7,418
            Genes (coding)                    :: 7,242
            CDSs (with protein)               :: 7,242
            Genes (RNA)                       :: 92
            rRNAs                             :: 5, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 74 of 176
            Pseudo Genes (incomplete)         :: 131 of 176
            Pseudo Genes (internal stop)      :: 12 of 176
            Pseudo Genes (multiple problems)  :: 39 of 176
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:42:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7931837
            Orig. end                         :: 7968985
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012382.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..37148
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /product="terpene"
                     /region_number="29"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..37148
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="neighbouring"
                     /product="lanthipeptide-class-i"
                     /product="terpene"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..24534
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24534
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14534](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14534)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(660..2102)
                     /locus_tag="SAM23877_RS34440"
                     /old_locus_tag="SAM23877_7253"
     CDS             complement(660..2102)
                     /EC_number="3.1.1.103"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020114285.1"
                     /locus_tag="SAM23877_RS34440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7253"
                     /product="serine hydrolase domain-containing protein"
                     /protein_id="WP_053141708.1"
                     /transl_table=11
                     /translation="MSFDEHGNWSVEGTWGARNSAGRKLDLARWQARLDQLCSQHHVPG
                     ASLAVLVDGTVHEWASGVLHRGTNVETTTDSVFQMGSIAKIYTATLVMQLIESGRLDLD
                     APVTDVLPDFSIGDPGATAMISTRRLLSHTSGLTCDFNHDSGRGDDCLAKYVEATKDVA
                     LDCPPGSAISYSSVGYNVLGRIVEVVTGKTWDAALKDLLLTPLGLTHTMTLPEEALRFR
                     AAMGHLGEPGQEPAPAPEWDMMPRSAGPYGRVIATAGDLARLARMHLAGGVAEDGTRVL
                     SEAAVALMQRREVDCPDKWTVSSDGWGLGWTLYDWNGVKGYGHDGASIGQYGYLRVVPS
                     AGVAVALLTNGGGAREVYAALYRELLADLAGVAMPEPFAPSATPPVVDWGPLVGTYRRE
                     GVVITVTEEDGAGHALYEFVDGMKDLSEPLQIDLLPVTETAFAGTGVGSAFSTDYTPVI
                     FSALPDGTRCVYVGMRCAPKTG"
     misc_feature    complement(2092..2101)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.29"
                     /tool="antismash"
     misc_feature    complement(2179..2194)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.19"
                     /tool="antismash"
     gene            2255..2965
                     /locus_tag="SAM23877_RS34445"
                     /old_locus_tag="SAM23877_7254"
     CDS             2255..2965
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482508.1"
                     /locus_tag="SAM23877_RS34445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7254"
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="WP_053141711.1"
                     /transl_table=11
                     /translation="MPADAKPITSVWARPHRPQREQLTREQIVAATIELLDAEGVEALS
                     MRKLGTRLKAGATSLYRHVANRDELIQLAVDDVFGELGPPAAATRRTWRTSVARAATEL
                     RALVLRHPWVGPELGQVGLLHVGPNAVRMTSGLLAQFQAAGFPEGEEDQAAGALMSYVV
                     GIATSEAAYLSLVTRSGVSERDWLSDHSSNFGEEVDPRQVREDRFAYGLDRILDGLASR
                     LPPGEDSGARRTGR"
     gene            complement(3363..5762)
                     /locus_tag="SAM23877_RS34450"
                     /old_locus_tag="SAM23877_7255"
     CDS             complement(3363..5762)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018956895.1"
                     /locus_tag="SAM23877_RS34450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7255"
                     /product="ricin-type beta-trefoil lectin domain protein"
                     /protein_id="WP_162492136.1"
                     /transl_table=11
                     /translation="MYPRLYPRRLGRRLAGTIIASLLAVGLSSSPSPADDSEAAALPPQ
                     EPGVTLRVFDVQAPLNEICTLKAGQTPNVDKLMPVIDWSSADDFGLESHFVTHVLGNLG
                     AAQSGGYTFRLTSDDGSRLWIDDQLVINHDGLHGPDPKDATVDLTAGSHSLRIEHFERD
                     GGQQLTLSWKPPGASAFSVVPNSVLSTDAGVVRVTAPGRKECEGGTDSPGDGLPLTGVH
                     PNYTLTNLRPNGFEPQVSAMDWLPDGRLAVATWGGSNNTAGEVYLLSNVTGSTGPDKVT
                     AKKVASGLREPMGIKHVDGKLYVSQKHELTELNDTNGDEVTDQYRRVATWPFGGNFHEF
                     AFGLLYQDGFFYLNLSVSINYGGATTDPQPAANRGTTIKVNKATGQVSYVAGGLRTPNG
                     IGWGPEGGMFVTDNQGGWLPSSKLVHIKQGRFFNHHTNPDGPFDSQPVTKPVLWLPQNE
                     IANSPSTPLQLKDGPFAGQMLFGDVTYGGIQRGFLEKVGGEYQGAVFRLTQGLEAGVTR
                     ISVGPDGALYAGGLGAGGNWGQEGKLTYGLQKLTPNGANAFDIRAMRAVPGGFELEYTQ
                     PLSTDTANELAGHYKIKQWRYVPTADYGGPKVDEEALTAQSATLSADRRTVTLAIPGLK
                     ADRVVHVRSPRPFSSAGGETLWSTEAWYTLNRLPGAASGTGEVKGVNGKCLDVDNSQTA
                     DGTKIQLWTCNSTGAQQWTLPGDGTVRALSKCLDVSDGGSTDGTKIQLWTCNGSGAQTW
                     QPQADGTVRNPQSGKCLDASGGTWNDGTPVHLWACHTGANQKWQLP"
     misc_feature    complement(5697..5699)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            6135..6767
                     /locus_tag="SAM23877_RS34455"
                     /old_locus_tag="SAM23877_7256"
     CDS             6135..6767
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452119.1"
                     /locus_tag="SAM23877_RS34455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7256"
                     /product="NAD(P)-binding domain-containing protein"
                     /protein_id="WP_053141713.1"
                     /transl_table=11
                     /translation="MRIGLLGTGNVARALAHGWSTAGHDVLLGSRRPKERTDLGLPVAS
                     LSETAAHAEALVNATPGAVSVELLHSIGASALAGTLLIDVGVGLSDDFTELSHPNSSLG
                     EQIQASFPLTPVVKTLCTMDSTVMTAPDGLDGPSTVFLSGDDAEAKRTTGRLLTDLGWP
                     PSSQLDIGGIVTARGQEHFALLFMGIAGGLGGHTFNINVVTPSSAQV"
     gene            complement(6922..8454)
                     /locus_tag="SAM23877_RS34460"
                     /old_locus_tag="SAM23877_7257"
     CDS             complement(6922..8454)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="other (smcogs) SMCOG1285: ferredoxin fdxC"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044343.1"
                     /locus_tag="SAM23877_RS34460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7257"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_053141714.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.5e-13, bitscore:
                     46.8, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAFAITQTCCSDATCVSVCPVNCIRPTPEEQAFGSTEMLHIDPKT
                     CIDCGACADACPVDAIFPVESLTAGQREYADMNAAYFEQAEEEAEGAGANASGPNFHSW
                     GEPAFDRVLPPDFGPLRVAIVGTGPAGMYAAEDLLLHTRAEVTLIDRLPAAGGLIRYGV
                     APDHPATKKIGDTFARFHTHPRVRMHLGLEVGGDVTTEEIAAHHDAVIYAVGAATDRRL
                     GIPGEDRTGSLSATTFVAWYNAHPDVAPDAVDLSSERVVVIGNGNVALDVARILVTDPE
                     ALADTGIARHALAELRHSKVREVVLLGRRGPDDAACTRPELLALKHLPEVDLVVDAHDP
                     RIGAVIDAAGPKDKAAVLRGVARETVDWSAPPSATGRRRRIVFRFLSTPVEVCGDAHMR
                     AVRVAGGAGELEIPAGMALRAIGYRGVPQPGLPYDEATGTVPHERGRVIGRAGTYVVGW
                     IKRGPSGGIGANRVCAAETVGTLLADAVSGALPAPTPGPKAFHRLARRRSRR"
     gene            complement(8478..9392)
                     /locus_tag="SAM23877_RS34465"
                     /old_locus_tag="SAM23877_7258"
     CDS             complement(8478..9392)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AurF"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019328148.1"
                     /locus_tag="SAM23877_RS34465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7258"
                     /product="diiron oxygenase"
                     /protein_id="WP_053141716.1"
                     /sec_met_domain="AurF (E-value: 5.7e-98, bitscore: 326.3,
                     seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MALNISRPRTKSRTPDDGIARRLLDSSAQLSYDPLTEVDWETPLD
                     TEFHGASPEWSTLYGTAYWNEMTEAQRKALTRQEAASVASTGIWFEMILQQMVLRDIYA
                     KDPTSDTFQWALTEIADECRHSIMFARGAKKLQAPAYRPHRTAVELGRLFKTVAFGEAA
                     YAAILVAEEVLDVMQRDWMRDERVVPFVRTINNIHVVEESRHMKFARDETRRHLARAGR
                     TRRQIQSLLIAVAAYVIVTSMVNRKVYANAGLDEERALREAKANEHHKSMMRSSCSGLM
                     EFLTSVGLLTKPALFFYQRANLI"
     misc_feature    9473..9486
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.9"
                     /tool="antismash"
     misc_feature    9668..9682
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.36"
                     /tool="antismash"
     gene            complement(10001..11362)
                     /locus_tag="SAM23877_RS34470"
                     /old_locus_tag="SAM23877_7259"
     CDS             complement(10001..11362)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978595.1"
                     /locus_tag="SAM23877_RS34470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7259"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_053143155.1"
                     /sec_met_domain="LANC_like (E-value: 1.1e-61, bitscore:
                     207.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNGTTDGGTREHPIGRSGRDLRERAAAVSAEILDRLADPAATMAA
                     TRIPAQAADDGVDEPIWAELTLGSGSPGLALAFAGAARDTTRQVPRAHAYLTAGTRAVS
                     GRPGAAGGIFKGPGALAFAVLLAHRTTGGYVSALQRFDTYQRDLVRTVLPPVEDRPLPT
                     IGHYEVVRGLTGVGRYLLARAESCEEPLTAVLDYLVRLSLGTVEHQGADVPRWWALDAP
                     RVGSEAAFPGGHLNLGLSHGVAGPLALMALAWEQKVRVPGQQEAMEATAALLRTWAVTD
                     EHGLFWPGYLSFAQWQRGPAAYDGSAKWPAWCYGTPGVSRALQLAGQALGRTDFTDLAR
                     ASVDRLLVLPRSAWGIDDHALCHGWAGALHLLGRLDERWQDPRLAELRDDIAADLVAAF
                     DPALPFGLRFTMTKVPFGSDVSGYLDGAAGVALALDSYAVDGTPADWDMPLLLA"
     gene            complement(11397..14534)
                     /locus_tag="SAM23877_RS34475"
                     /old_locus_tag="SAM23877_7260"
     CDS             complement(11397..14534)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004936802.1"
                     /locus_tag="SAM23877_RS34475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7260"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_053141718.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 7.8e-171,
                     bitscore: 568.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 1.2e-19,
                     bitscore: 69.5, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.9e-33, bitscore:
                     113.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAAESEAQQATSAFEVREPVLVRMASRPRGAALATVDAAEPVSGA
                     RQLASDPLLGQAVRVASGSLARSLAGLASDEGATALGRKRTLSAARTLTRYARRAGARP
                     TPFGLFAGVGTARFGSAAKAEPGTGEVAVRLDGAWLRRRVLAWLAEPSVRRRVDVVIND
                     LCFLRDGRLYLRTGGQEQSVRDNALVGAVRERARTPVPYAELLVTLTERFPTLDAERLD
                     RQLAGLVQHGFLLTSITPHRIDAELLDGIEAVLEAALPNDAQALRDVRAACARHQEDPP
                     GLGGDSWQQLLDEVRRLDVPGTDGDAHARPPLHVDLHIPGEFVVPEAVGQEVCRYAAAI
                     WAITPEWTTLAYMRDYRERFIERYGTACAVPLGELVDPHRGLGLPPEYGAEPVYARNGP
                     GDEADGPRRAMIGELLQEAVLSGGDLVLTDDIVGRLAEVAGHDPAAAPPRSLELCFQVL
                     AESTAALDRGDFRLLGSPHIGAWTAGATAGRFAAAAGLTGELARLAADTAVDPDDAVIA
                     AQVELMPHEPRGLNIVQVPRLLPYRIPVGIADDRDDPCCLDWRSLVVAAGSDGLRLLCP
                     ESGRPVRPVLPHMLALDTQAPPVARFLMDLAAARPRMWSGWDWAGHDALPYLPRIRYGR
                     VVAMPGRWLPGRRLRDAARAQGAEVWEQGLDAWRRRLAVPDRLQIARNDQMYPVDLRES
                     WDRSLLRAELTAAHPQFVLYEDLTADGAGLGWNGGHSTEIVVPLAGARRPAGRTAPEDT
                     ARARTALPVRPAPARIHLPGEDWLFVKWYAEPSAHDALLVDHLPAVLAEVEDEVDRWFF
                     LRYQDPEPHLRLRFHGDPAALNGRVLPVVSRVSRALVERGALRTMTLDTYRPESDRYGG
                     EALQEAAERFFRTDSLSALVQLRALRGVARALPAAVLAGLGHAVLLESLGDWDWCGWVD
                     RMFTKTPEHEVYQRHRAVADRLIRPGNAVSSAAEALGAPSLGALWSESPEPRAYGQLLL
                     SAPEADRDEALLSLLHMRHNRLFGIDRAAETRGYAVLRGAVRTHAGRLRHEGGSGR"
     aSDomain        complement(13812..14060)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_SAM23877_RS34475_Lanthipeptide_LanB_R
                     RE.1"
                     /evalue="4.60E-22"
                     /identifier="RREFam001.1"
                     /label="SAM23877_RS34475"
                     /locus_tag="SAM23877_RS34475"
                     /protein_end="241"
                     /protein_start="158"
                     /score="69.5"
                     /tool="antismash"
                     /translation="VVINDLCFLRDGRLYLRTGGQEQSVRDNALVGAVRERARTPVPYA
                     ELLVTLTERFPTLDAERLDRQLAGLVQHGFLLTSITPH"
     gene            complement(14620..14781)
                     /gene="lanA"
                     /locus_tag="SAM23877_RS36835"
                     /old_locus_tag="SAM23877_7261"
     CDS             complement(14620..14781)
                     /codon_start=1
                     /gene="lanA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) strep_PEQAXS"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978597.1"
                     /locus_tag="SAM23877_RS36835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7261"
                     /product="SCO0268 family class II lanthipeptide"
                     /protein_id="WP_063484126.1"
                     /sec_met_domain="strep_PEQAXS (E-value: 1.7e-41, bitscore:
                     138.7, seeds: 4, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTEIVLSHEAPELDLDLDLRVSDLPEQAESFGQGTFTSPSSYAI
                     GTRCPICC"
     CDS_motif       complement(14695..14781)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MRTEIVLSHEAPELDLDLDLRVSDLPEQA"
                     /locus_tag="SAM23877_RS36835_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14620..14694)
                     /prepeptide="core"
                     /locus_tag="SAM23877_RS36835_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-8.70"
                     /molecular_weight="2386.7"
                     /monoisotopic_mass="2385.1"
                     /core_sequence="ESFGQGTFTSPSSYAIGTRCPICC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MRTEIVLSHEAPELDLDLDLRVSDLPEQA"
                     /leader_location="[14694:14781](-)"
                     /alternative_weights="2404.7"
                     /alternative_weights="2422.7"
                     /alternative_weights="2440.7"
                     /alternative_weights="2458.7"
     misc_feature    complement(15484..15499)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.68"
                     /tool="antismash"
     gene            complement(15534..15737)
                     /locus_tag="SAM23877_RS34485"
     CDS             complement(15534..15737)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SAM23877_RS34485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_053141722.1"
                     /transl_table=11
                     /translation="MAASGSGHRRKRHLVALSPGLLLTVTVTWLDEGHRAAEQPADDEV
                     RVGSAQVAAAGEHRPAHPLPLR"
     gene            complement(15738..16241)
                     /locus_tag="SAM23877_RS34490"
                     /old_locus_tag="SAM23877_7263"
     CDS             complement(15738..16241)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512599.1"
                     /locus_tag="SAM23877_RS34490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7263"
                     /product="hypothetical protein"
                     /protein_id="WP_053141725.1"
                     /transl_table=11
                     /translation="MSWLPDDFVHPVLVPLPGGGHHLRPIREADTPLDYPAVMGSRERL
                     WTIYGPAWGWPAATMTFEADRADLLRHEKEIAAHQSFNYALFDSAETALLGCVYIDPPE
                     RVGADGDISWWVVDDLVGSKVEQALDALVPQWIATDWPFEQPRFIGREISWPDFLALPE
                     HPAA"
     cand_cluster    16111..37148
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    16111..37148
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[26110:27148](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(26111..27148)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="2"
     gene            complement(16397..16837)
                     /locus_tag="SAM23877_RS34495"
                     /old_locus_tag="SAM23877_7264"
     CDS             complement(16397..16837)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325555.1"
                     /locus_tag="SAM23877_RS34495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7264"
                     /product="hypothetical protein"
                     /protein_id="WP_053143157.1"
                     /transl_table=11
                     /translation="MFAASALTGCTLTDLARDCEGADARVEEMAALGILDSRPDRATVA
                     RGFEEVDAGCWADSGDVTVYAERTYAFPGTRAEVAAHYRTAAQQDGWSPDPDAAPDDLS
                     FVRKTMSLRVVFLTAELLAEEGHGSRPDLSTDAGYSISVDSY"
     gene            17037..17624
                     /locus_tag="SAM23877_RS34500"
                     /old_locus_tag="SAM23877_7265"
     CDS             17037..17624
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SAM23877_RS34500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAM23877_7265"
                     /product="hypothetical protein"
                     /protein_id="WP_053141726.1"
                     /transl_table=11
                     /translation="MTSGGSDVDAALVALAWERLQSETPPAAVCGELAARTPCWWDAVL
                     AVGRAMGIPESELLRRLHGTPQQVRSEFRPGEEELYGDLMAVLGVFDIPRQLDERESVI
                     AESLRTAMRAMGGVASGHGLGLSRRLVTGELESVFRSLARSGPRADRGRPAEFWGALVA
                     AGELLDPADGDERGTVAQALAECRLHLANCAR"
     gene            <17670..18047
                     /locus_tag="SAM23877_RS34505"
                     /old_locus_tag="SAM23877_7266"
                     /pseudo=""
     CDS             <17670..18047
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020126547.1"
                     /locus_tag="SAM23877_RS34505"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7266"
                     /product="GNAT family N-acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="LRSLHLLAMVQEFGSTCLVARAEDGIRGYVFGFVTPGGTGYVHLI
                     ATRDDARGTGLGRRLYTAFAEAAERHGARTLKAITSVGNTGSVAFHRSLGFDATIVDGY
                     DGPGRAMAVFRRDLPLEFPRP"
     gene            complement(18224..18766)
                     /locus_tag="SAM23877_RS34510"
                     /old_locus_tag="SAM23877_7267"
     CDS             complement(18224..18766)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008735208.1"
                     /locus_tag="SAM23877_RS34510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7267"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_079030861.1"
                     /transl_table=11
                     /translation="MVTLETPRLILRRWREEDVAPMAAVNADPEVMRWIRDGSVLDEQQ
                     TRRRVQAWESEWESEGFGLFAVEIRSTGELAGFTGLSVPNFLPEVLPAVEVGWRLGRSH
                     WGQGLATEAAAAAVRFGFQERGLERIVSIAQVGNNASERIMTKLGMHPVRETVNPSCDR
                     RVRVFELASDQYATTAR"
     misc_feature    complement(18953..18968)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.03"
                     /tool="antismash"
     gene            18987..19529
                     /locus_tag="SAM23877_RS34515"
                     /old_locus_tag="SAM23877_7268"
     CDS             18987..19529
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030151 - molybdenum ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014060654.1"
                     /locus_tag="SAM23877_RS34515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7268"
                     /product="MOSC domain-containing protein"
                     /protein_id="WP_174532275.1"
                     /transl_table=11
                     /translation="MSGTVTAVSSNGEYTFTKPNRDSITLLAGLGVEGDVHAGVTVKHR
                     SRVAQDPTQPNLRQVHLIHEELFAEVRAAGFEVLPGDLGENITTSGIDLLGLPVGTLLR
                     IGDEAVLEVTGLRNPCLQIDNFQDGLLKQVVGRDEAGNIVRKAGIMSIVKNGGVVRPGD
                     TIKVELPGGPHRPLERV"
     gene            complement(19681..20058)
                     /locus_tag="SAM23877_RS34520"
                     /old_locus_tag="SAM23877_7269"
     CDS             complement(19681..20058)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018567842.1"
                     /locus_tag="SAM23877_RS34520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7269"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_079030598.1"
                     /transl_table=11
                     /translation="MAQEQTTDSGRPDQTDRLSAVSTVIDGIRVLALTGEIDNDTGGQL
                     RQALDVAGTDRPRIVLDMRQVTFMDSSGINILIAAHQDIAASGGWLRLAAPTDAVLRVL
                     RLVGVDQVIDCRSTLDGTLTP"
     misc_feature    complement(20176..20189)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.75"
                     /tool="antismash"
     gene            20224..20703
                     /locus_tag="SAM23877_RS34525"
                     /old_locus_tag="SAM23877_7270"
     CDS             20224..20703
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019524904.1"
                     /locus_tag="SAM23877_RS34525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7270"
                     /product="ATP-binding protein"
                     /protein_id="WP_235614656.1"
                     /transl_table=11
                     /translation="MEATPVGEDGPAPYEQVLQTTTALDGDSADIGRARHVAAAFLSRV
                     QAEHGLPVSQRAMEVTQLVISELVTNSRKYAPGPILVDLRITGDMVEVAVWDSDSALPM
                     ARAADAGRVGQHGLEIVMAVAQGFEARREPVGKRITVRIALFDDPGGAVSGRTLL"
     gene            complement(20920..21405)
                     /locus_tag="SAM23877_RS34530"
                     /old_locus_tag="SAM23877_7271"
     CDS             complement(20920..21405)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018383232.1"
                     /locus_tag="SAM23877_RS34530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7271"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_053141733.1"
                     /transl_table=11
                     /translation="MSALLAGDLSGAGREAGISLTEYFMTDSARWLWQFRLDQMAADPG
                     HARWMVRQAVVGDGGLVVGHAGFHGPPDEAGMVEIGYSVAPDFRRQGYGRSALVELLRL
                     AGAEPTVTTVRATIGPDNVASLATISGFGFVQVGEQWDEEDGLELVFEVPACRLPLT"
     gene            complement(21611..>21895)
                     /locus_tag="SAM23877_RS39815"
                     /old_locus_tag="SAM23877_7272"
                     /pseudo=""
     CDS             complement(21611..>21895)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010268081.1"
                     /locus_tag="SAM23877_RS39815"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7272"
                     /product="VOC family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="QVEIGSWVPTVEEVRARQMPPTLVFIRVPEVKTVKNRLHLDVSPI
                     DRSTENEVSRLLGLGATRADVGQGADRNWVVMADPEGNEFCVLRTLVQG"
     gene            complement(21931..22707)
                     /locus_tag="SAM23877_RS40925"
                     /old_locus_tag="SAM23877_7273"
     CDS             complement(21931..22707)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010981524.1"
                     /locus_tag="SAM23877_RS40925"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7273"
                     /product="hypothetical protein"
                     /protein_id="WP_053141735.1"
                     /transl_table=11
                     /translation="MTTQPLPTERSAPQTASVVTDLPFKPQLVKAVFRDVTSLHVSRPA
                     AWAAASVTRTVLTEIIDGARSAAAEEARKRLIPKDLISAIDRNIEVEVGSEWYLHSPTF
                     HGLMGEVRNADGALVSLRQRRGARTPRGVAGAHRFEAGVRRLLESRGVRAVPAMVRDLD
                     GIASVFLTGLARDAAKVVREGGVKRFGTVSPVVPGEPAPVPLLKDPLLALSTRCGDGRT
                     VGGDDVLAAVTMQLFGDLRQRAITEAVEMTRNTRGN"
     gene            complement(23148..24116)
                     /locus_tag="SAM23877_RS34545"
                     /old_locus_tag="SAM23877_7274"
     CDS             complement(23148..24116)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156141.1"
                     /locus_tag="SAM23877_RS34545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7274"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_063796803.1"
                     /transl_table=11
                     /translation="MSPVLDTAFIPPRDREELVRHAVWESLVAVDIEHRPAAEDISVRI
                     GLGDVGPLTFCTARASAVTVRRTERLARADEEPAVFLGLQVSGTSLVVQNDRECVLRPG
                     ELAVYESVSPYTLLFDEGVDHHFLRFPRAALALPDRLLRDTSTVTLGSDNPVARLAFDY
                     FCQLAATDELHQGGHADAVVEPSIELLRAVLTWQHGNSELAKGPLEATLTLRVTQYVRA
                     HLADPDLSAARIARAHGISVRHLYAVLSRSGISLGDWIRTHRLAACRRELAGPKGRSRT
                     IAAVGRSWGFVDASHFSKVFKQAYGLSPRAWRDHHRPRSST"
     gene            24500..25393
                     /locus_tag="SAM23877_RS34550"
                     /old_locus_tag="SAM23877_7275"
     CDS             24500..25393
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SAM23877_RS34550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAM23877_7275"
                     /product="hypothetical protein"
                     /protein_id="WP_053141737.1"
                     /transl_table=11
                     /translation="MKQKAFVAAAVTAVLCCVAGCDVQTKQQATPDVEVRDLTVREEIE
                     IGRAEERLVKTCMEEKGHRYWELPVPGVDERKAGRYVTDDVEWARKHGYGRGFEERSEE
                     IRRTDPTTVYQNKLRPPERAAFNRALDGDYRDRMSVELPGGTGTVDAPRGGCANEARAK
                     LYGDSEAWFVTRKTIEGILPLYGRDLMEDARLKKPLAKWARCMKEAGRPFADPGRLRRN
                     RMVVTDGMPSAKAHEFDRTLAVLDATCARKTSLAEIMRALETSYREKALQRYERERDDY
                     RTMRLHALREAEDVLS"
     gene            25478..25948
                     /locus_tag="SAM23877_RS34555"
                     /old_locus_tag="SAM23877_7276"
     CDS             25478..25948
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003947908.1"
                     /locus_tag="SAM23877_RS34555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7276"
                     /product="hypothetical protein"
                     /protein_id="WP_053141739.1"
                     /transl_table=11
                     /translation="MRKLSAAAVGAALVGISLVGPLPSASAAAAATCADNYDNALAGYM
                     YAYNGANCEGQLGLAVGNDQNWGDSASSFQGSDTNRASSVLNMGRYSQVKFFANPTTGS
                     AFNPHICLTRAEGYASNLSDDYFMEDPVFGSANNSISAHIWVELTACSALAQ"
     gene            complement(26111..27148)
                     /locus_tag="SAM23877_RS34560"
                     /old_locus_tag="SAM23877_7277"
     CDS             complement(26111..27148)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="SAM23877_RS34560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7277"
                     /product="hypothetical protein"
                     /protein_id="WP_053141741.1"
                     /sec_met_domain="T1TS (E-value: 7.2e-39, bitscore: 133.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVIGDVPAFTGTPVVGHPHVEEIQSQSLKWMGDMGLLPDPKVRAR
                     YAGMRVGAWPSHCYPYTSFDYGLLLAYWWSWWTYVDDVAPQMDCDQWLKLSLDMEHVLR
                     CAGDSAVPAGGSDSCQPVLRSLADLCRRTAAAGSDAYYDQVAAGNIDALYGFGLEAFNE
                     RLRRAPDIDLEVSRHCEYLRGRYKTIGLILDVAYIEGALGFDVPSSVRRTTAWQDVLET
                     AFSVMILQNDLVGAARDEAASDTHNAVNLLRRLHGLSRADAEHQITRAIAARIAEFLHL
                     ERVFPDHVTDLGLPALDLERVQDIIGKLKIMSQGALAWYTETSRYIPASRTANRADNFA
                     SRCQT"
     misc_feature    complement(27147..27165)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.68"
                     /tool="antismash"
     misc_feature    complement(27330..27341)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     misc_feature    complement(27422..27436)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.12"
                     /tool="antismash"
     misc_feature    complement(27425..27440)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.74"
                     /tool="antismash"
     gene            27470..28234
                     /locus_tag="SAM23877_RS34565"
                     /old_locus_tag="SAM23877_7278"
     CDS             27470..28234
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014174146.1"
                     /locus_tag="SAM23877_RS34565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7278"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_053143168.1"
                     /transl_table=11
                     /translation="MERNLAEHACHLHRSMTGATVTDAGDLLVADSGLDDDTFNIVAAA
                     RFTAADATARITETAGTLARTGRRFSWWVGPASTPRDLGTRLTAAGLPPSERETAMWAE
                     LDDTLPPPAAQELDIQRVATPGQLADYAMVLAANWDPPAETVRRFFAQATPQALAAQCP
                     ARYLVGYVENRPVCSAEVFHHAGVAGIYNISTLAAHRRRGYGGAITLAALRSARDRGHR
                     IAVLQASADGEPVYHRLGFRSCGQFTEHAVDP"
     gene            28400..29386
                     /gene="bla"
                     /locus_tag="SAM23877_RS34570"
                     /old_locus_tag="SAM23877_7279"
     CDS             28400..29386
                     /EC_number="3.5.2.6"
                     /GO_function="GO:0008800 - beta-lactamase activity
                     [Evidence IEA]"
                     /GO_process="GO:0030655 - beta-lactam antibiotic catabolic
                     process [Evidence IEA]"
                     /GO_process="GO:0046677 - response to antibiotic [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="bla"
                     /gene_functions="resistance (resist) ClassA"
                     /gene_kind="resistance"
                     /inference="COORDINATES: protein motif:HMM:NF033103.1"
                     /locus_tag="SAM23877_RS34570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7279"
                     /product="class A beta-lactamase"
                     /protein_id="WP_063796804.1"
                     /transl_table=11
                     /translation="MTRHLRLRLSLATLTALALLGGLACAVGALTGDTHAADGVKASDS
                     AARVQGSASSASGLSKTLRALEKSYDGRIGAVGIDLGDGRTVAYRADERFPFNSSFKVF
                     ACAAVLDKARTGDPGLMEQVVRWEPADMAGLTANSPETTEYTDTGMTPAQLCRAGITKS
                     DGFAGNLLLEQIGGPRGLTAFFRAVGDRSSRLDRPEPRLTEWEPGGVRDTTTPAAAART
                     FTELTTGDTLQGGDRARLVGWLKASVTGADRIKAGLPKDWTVGNKTGTGGASNHGTASD
                     LAIVWPPGTDAPLILSVYTNRNHDNTAHDDKVIASTATALATALGRV"
     misc_feature    28424..28426
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            29665..30105
                     /locus_tag="SAM23877_RS34575"
                     /old_locus_tag="SAM23877_7280"
     CDS             29665..30105
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386767.1"
                     /locus_tag="SAM23877_RS34575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7280"
                     /product="OsmC family protein"
                     /protein_id="WP_053141743.1"
                     /transl_table=11
                     /translation="MSENSERSVTVERISSGQFVATNARGGSISFGTSPGSGPDTGFTP
                     VELFLAAIGGCTAVDVDVATGRHAEPTQFSVRVTGDKISDDLGNRMTNLEVTFTVAFPD
                     GEEAERARAILPRAVKASHDRLCTVSRTVETGTPVTTTIADA"
     gene            complement(31030..31821)
                     /locus_tag="SAM23877_RS34580"
                     /old_locus_tag="SAM23877_7282"
     CDS             complement(31030..31821)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF020795.4"
                     /locus_tag="SAM23877_RS34580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7282"
                     /product="DUF1963 domain-containing protein"
                     /protein_id="WP_053141744.1"
                     /transl_table=11
                     /translation="MFEKNLAVAAELFRSQAAARNLPPQTVEAFIRGVRPAIHLAESNG
                     PRCVGQRGGDPSLPLGAPIPANPFVFSIDCALLPERATDLPLPPDGRLLFFASVEWDGN
                     GEGITSDAVRYVPAGTPTRPRPSTGPSSTQSPYRQRPLGIVGSGLSALDSYDFARKQWG
                     EEHDEEQEDLALKLGEVWQRATDPQLLDVSGPIQLGGNATATELDELLEAEDGEDWVNL
                     ASWTCQDEDLDSIESATVVWAIQRHDLAALRFDRVFTHQEQ"
     misc_feature    complement(31808..31821)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.15"
                     /tool="antismash"
     misc_feature    complement(31814..31829)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.79"
                     /tool="antismash"
     gene            complement(31934..32554)
                     /locus_tag="SAM23877_RS34585"
                     /old_locus_tag="SAM23877_7283"
     CDS             complement(31934..32554)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019324494.1"
                     /locus_tag="SAM23877_RS34585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7283"
                     /product="hypothetical protein"
                     /protein_id="WP_053141746.1"
                     /transl_table=11
                     /translation="MSNAIWDALVATPLPEVRHRAAVVDDLAEVKPVTVAGAHRLAWND
                     RGGQSAVWYFTDDGRVLLLTFDHESSLNLYAEEDFALQESFFEGVPEPLVALVRDRPEN
                     YESLNLTDSATGRTIHYAGGVFWYDGTHWHVSSGLAEHCRREDVDLFGESGFDYCLGVY
                     RFGQDFTAETSVAIREEDGRYDDEKQKEADLTSVREVLIRHGR"
     gene            32849..33241
                     /locus_tag="SAM23877_RS34590"
                     /old_locus_tag="SAM23877_7284"
     CDS             32849..33241
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040072.3"
                     /locus_tag="SAM23877_RS34590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7284"
                     /product="DUF6355 family natural product biosynthesis
                     protein"
                     /protein_id="WP_053141752.1"
                     /transl_table=11
                     /translation="MKLSLRPRRAVLAAASGALTALAAVALPGPAHAESVRGPEVRQAA
                     AGSLAPCGFFRYSVRESQFAGYGHCGETTVLVHVDVRGGGSTNDYHLCVGPGATQLPGA
                     GPNYLNAYYIGGAGCALGSRTGHSAH"
     gene            complement(33343..34332)
                     /locus_tag="SAM23877_RS34595"
                     /old_locus_tag="SAM23877_7285"
     CDS             complement(33343..34332)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006132796.1"
                     /locus_tag="SAM23877_RS34595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7285"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_053141755.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 2.7e-17, bitscore:
                     62.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIAQHPRAGRILPLALAVPATVLLAAMPTAASESGGPTGSHAS
                     IKPTIVLVHGAWADASGWDEISERLQSQGYPVVATANPLRSLSGDAAYLSARLKSIKGP
                     IVLVGHSYGGAVITNAAAGNPNVTSLVYVAGFAPDKGETTLELAAKYPGSRLTDDPEAP
                     VPTALDAVPLGDGPTDVDLYIKPDKFSDVFLSDRLDRSQADILAAAQRPAAVVTGSEPT
                     EAAAWKTIPSWYLVPTDDRTIGTENLRFMAERADSTTVEVDAPHAVMETNPGDVTRLIL
                     RAAEDSRPSLAGTGTSAPALAAMAGASALAVAGGTTLVLRTRRPAHAS"
     gene            34600..35430
                     /locus_tag="SAM23877_RS34600"
                     /old_locus_tag="SAM23877_7286"
     CDS             34600..35430
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (23-262). E-value:
                     2.2e-37. Score: 120.9. Matches aSDomain:
                     nrpspksdomains_SAM23877_RS34600_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010273204.1"
                     /locus_tag="SAM23877_RS34600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_7286"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_053141757.1"
                     /sec_met_domain="PF00561 (E-value: 7.1e-30, bitscore:
                     103.2, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.2e-17, bitscore:
                     62.6, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGTVTTQDGTEIFYKDWGPRDAQPIVFHHGWPLSSDDWDNQMLYF
                     LGHGYRVIAHDRRGHGRSSQSASGHEMDTYAADVAAMTDALDLHDAVHIGHSTGGGEVA
                     RYVARAKPGRVAKAVLVGAVPPLMVKSEANPGGLPIEVFDGFRASLAANRAQFYIDVPA
                     GPFYGFNRPGAEVSQGVIDNWWRQGMRGAANAHYLCIKAFSETDFTEDLKQIDVPVLVA
                     HGTDDQIVPYDDSAPLSVKLLRNGRLKSYDGYPHGMLTTHPEVLNPDLLAFVKE"
     aSDomain        34669..35385
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAM23877_RS34600_Abhydrolase_1.1
                     "
                     /evalue="2.20E-37"
                     /label="SAM23877_RS34600_Abhydrolase_1.1"
                     /locus_tag="SAM23877_RS34600"
                     /protein_end="262"
                     /protein_start="23"
                     /score="120.9"
                     /tool="antismash"
                     /translation="PIVFHHGWPLSSDDWDNQMLYFLGHGYRVIAHDRRGHGRSSQSAS
                     GHEMDTYAADVAAMTDALDLHDAVHIGHSTGGGEVARYVARAKPGRVAKAVLVGAVPPL
                     MVKSEANPGGLPIEVFDGFRASLAANRAQFYIDVPAGPFYGFNRPGAEVSQGVIDNWWR
                     QGMRGAANAHYLCIKAFSETDFTEDLKQIDVPVLVAHGTDDQIVPYDDSAPLSVKLLRN
                     GRLKSYDGYPHGMLTTH"
     gene            35507..36049
                     /locus_tag="SAM23877_RS34605"
                     /old_locus_tag="SAM23877_7287"
     CDS             35507..36049
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SAM23877_RS34605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SAM23877_7287"
                     /product="hypothetical protein"
                     /protein_id="WP_053141759.1"
                     /transl_table=11
                     /translation="MRTKTSGVTVRRCASIDVILRQHRIALGADFHTYRHHVYRGLNYQ
                     LALLGRDRPSTTMQLAWAVHDLGMWTAGTFDYLGPSAGLARRHAPAVGRVDLPLALTMI
                     ATHHRVRSVPDPEVETFRRADLVDVLHGLPPTASGRVPVRAVTRVFPYLGLHRCLLRRA
                     AAYACRHPRKPLPMVRW"
     gene            36125..36310
                     /locus_tag="SAM23877_RS41975"
                     /pseudo=""
     CDS             36125..36310
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018559356.1"
                     /locus_tag="SAM23877_RS41975"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MHGRPLPASPPGAAFARQGL"
     misc_feature    36868..36883
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.47"
                     /tool="antismash"
ORIGIN
        1 ccgagaagca ggcgcgggcc gtcgtcgacg aggtgcacgg caagggagcc aaggccgtcg
       61 ccctccagtc cgaccaggcg gacacgagcc gggcgccggc actgatcgac gacgtggtgg
      121 cgcacttcgg cggcctggac atcctcgtca acaacgcggc gatctccgcg gccggcgcgg
      181 tggacgaccc ggacgccgac accgccgcgc tggaccggat gcacgccacc aactacctcg
      241 gcgtgatcgc cgtcatccgg gccgccgccc gagtgctgcg cccgggcggc cgcgtcatca
      301 cggtgagttc cggactgggc acccgggtcg gcgccccggg cctcgccgac tactcggcga
      361 ccaagtccgg gatcgagagg tacaccatgg gcgtcgcacg cgacctcggg ccccggaaca
      421 tcacggccaa cgtcgtggag gccggactga tggagggcgg catgcaaccg ccggacgccg
      481 agaccctcaa gctcctggtc ggctcgctgt ccctgcaacg catggggcac cccgacgaaa
      541 tcgccgcggc catcgccttc ctggcgagcc ccgccgcgtc gtacgtcacg ggcgcggtgc
      601 tggacgccca cggcggctac aacgcctgaa cccgaacgtc ggccggccgg cgcggtccgt
      661 cagccggtct tgggggcgca gcgcatgccg acgtagacgc agcgtgtgcc gtcgggcagg
      721 gcggagaaga tcaccggtgt gtagtccgta ctgaaggctg aacccacacc cgtgccggcg
      781 aaggccgttt cagtgaccgg cagcaggtcg atctgcaggg gctccgagag gtccttcatg
      841 ccgtcgacga actcgtagag tgcgtgcccg gcgccgtcct cctcggtcac cgtgatgacc
      901 acgccctcgc gccggtacgt gccgacgagc ggaccccagt ccaccacggg gggcgtggcc
      961 gacggggcga agggctccgg catggccacc cctgccagat cggcgagaag ctcgcggtag
     1021 agggctgcgt acacctcacg cgcgccgccg ccgttggtga gcagcgcgac ggcgacgccg
     1081 gccgacggca ccacgcgcag gtagccgtac tgcccgatgg aggcgccgtc gtgaccgtat
     1141 cccttgacgc cgttccagtc gtacaaggtc cagcccagac cccaaccgtc cgagctgacc
     1201 gtccatttgt cagggcagtc cacctcccgg cgttgcatca gggccactgc cgcctcggag
     1261 agcacgcggg tgccgtcctc ggccacgccg ccggcaaggt gcatccgcgc aagccgggcg
     1321 aggtcgcccg ccgtggcgat gaccctgccg taagggcccg ccgaccgcgg catcatgtcc
     1381 cactccggcg ctggtgccgg ctcctggccc ggctcgccca ggtgccccat ggccgcgcgg
     1441 aagcgcagcg cctcttcggg cagggtcatg gtgtgggtga gaccgagcgg ggtcagcagc
     1501 aggtccttga gagctgcgtc ccacgtcttg ccggtcacca cctcgacgat ccggccgagc
     1561 acgttgtagc cgacgctgct gtacgagatc gcactgccgg gcgggcagtc gagcgcaacg
     1621 tctttcgtgg cctcgacgta cttggcgagg cagtcgtcgc cgcgcccgct gtcgtgattg
     1681 aagtcgcagg tgagcccgct ggtgtggctg agcagtcgac gggtggagat catcgcggtc
     1741 gctccggggt caccgatgga gaagtccggc aacacgtccg tgaccggtgc gtccagatcg
     1801 agtcggccgg actcgatgag ctgcatcacc agggtggccg tgtagatctt ggctatcgag
     1861 cccatctgga agaccgagtc ggtcgtcgtc tccacgttgg tgccgcggtg caggacgccg
     1921 ctcgcccatt cgtggacggt cccgtcgacg aggacggcca gggacgctcc cggcacgtgg
     1981 tgctgggagc agagctggtc gaggcgagcc tgccaccggg cgagatccag ctttcgcccg
     2041 gccgagttcc gggctcccca cgtcccttcg acgctccaat tgccgtgttc gtcaaaactc
     2101 ataccgttca gcacggctga cccccttggt ggcgtacgac gttctctcga tgcgcacact
     2161 gtacgcatca gagatcagcg ttcgcaagcg gcgtacagtg tcggctacgg tgagggacga
     2221 caaacagcag accgaccgat gggagttggc gcgtatgccc gccgacgcga agccgatcac
     2281 ctccgtgtgg gcgcgtccgc atcgcccgca gagagagcag ctgacgcggg agcagatcgt
     2341 ggccgcgacg atcgagctgc tggacgcgga gggtgtcgag gcgctcagca tgcgcaaact
     2401 cggcacccgc ctgaaggccg gggccacttc cctctaccgg catgtcgcca atcgggacga
     2461 gctgatccag ctggccgtgg acgacgtgtt cggtgagctg ggcccgccgg ccgccgccac
     2521 ccgcaggaca tggcgcacgt ccgtcgcccg cgccgccacc gagctgcggg cactcgtcct
     2581 gcgccacccc tgggtcggtc cggaactcgg ccaggtcggg ctactccacg tcggcccgaa
     2641 cgccgtccgt atgacatcgg gtctgctcgc tcagttccag gcggccggtt tccccgaggg
     2701 tgaggaggac caggcggcgg gggcgctcat gtcctacgtc gtcgggatcg ccaccagcga
     2761 ggccgcgtac ctttccctgg tcacccgcag tggtgtttcc gagcgcgact ggctgtcgga
     2821 ccacagttcg aacttcgggg aggaggtgga cccgaggcag gtccgtgagg accgcttcgc
     2881 gtacgggctc gaccggatcc tcgacgggct cgccagtcgg ctcccgccgg gcgaggactc
     2941 tggggctcgc cgcaccgggc ggtgacatgg cgacaaccgt tccgctcggc cgaccgtagc
     3001 gacgagcgtg cgacggagac ccgctggctg cgatgagccg ggcgcggctt cggcatcccg
     3061 cgggtcggcg gtcgggggcc acggaacacg gctgttcgcc ggggctcgca cacctgagag
     3121 tccgttcgga tcaccccgcc gtcacgaccg tccggctcac accgccgtcg cgtccgtcgt
     3181 gagggcgcgg tcgatctgtg cgggggacag ggcgtgctcg atcgccagga tgcccgcgcc
     3241 gagcacgccc gcgttctcgc cgatccgccc cgacaccgaa caggcgggcc cccggctccc
     3301 gtggggagat gccggggccc gccttcggcg ctgccacccg cagggtggtg ccggcctgat
     3361 cgtcagggca gttgccactt ctggttggct ccggtgtggc aggcccacag gtggaccggg
     3421 gtgccgtcgt tccaggtgcc gccggaggcg tcgaggcact tgccggactg cgggttgcgt
     3481 accgtgccgt cggcctgcgg ttgccaggtc tgtgcgccgc tgccgttgca ggtccacaac
     3541 tggatcttcg tgccgtcggt gctgccgccg tccgacacgt ccaggcactt gctcagggct
     3601 cgtacggttc cgtcgccggg cagcgtccac tgctgggcgc cggtgctgtt gcaggtccac
     3661 agctggatct tcgtgccgtc ggccgtctgg gagttgtcga cgtccaggca cttgccgttg
     3721 acgcccttca cctcaccggt cccggacgct gcccccggca gtctgttgag cgtgtaccag
     3781 gcttcggtgc tccagagcgt ttcgccgccg gccgagctga aggggcgggg agagcggacg
     3841 tggaccacgc ggtcggcctt gaggcccggg atggcgaggg tgacggtcct gcggtcggcg
     3901 gagagcgtgg ccgactgcgc ggtgagcgcc tcctcgtcga ccttggggcc gccgtagtcg
     3961 gcggtcggca cgtagcgcca ctgcttgatc ttgtagtggc cggccagttc gttcgccgtg
     4021 tccgtcgaca ggggctgggt gtactccagc tcgaagccgc ccggtacggc gcgcatggcg
     4081 cggatgtcga aggcgttggc gccgttgggg gtcagcttct gcagaccgta ggtgagcttg
     4141 ccctcctggc cccagttgcc gcccgcgccc agcccgccgg cgtagagcgc gccgtccgga
     4201 ccgacgctga tccgggtgac cccggcctcc agtccttgcg tgagacggaa gaccgctcct
     4261 tgatactcgc cgccgacctt ctccaggaaa ccgcgctgga taccgccgta ggtcacgtcc
     4321 ccgaacagca tctggccggc gaacggcccg tccttcagtt gcaaaggcgt gctgggcgag
     4381 ttggcgatct cgttctgcgg gagccacagc accggcttgg tcaccggctg ggagtcgaag
     4441 ggcccgtccg ggttggtgtg gtggttgaag aatcggccct gcttgatgtg cacgagcttg
     4501 gacgagggga gccagccgcc ctggttgtcg gtgacgaaca tgccaccctc ggggccccag
     4561 ccgatgccgt tcggggtgcg cagcccaccg gcgacgtagg agacctggcc cgtcgccttg
     4621 ttcaccttga tggtggtgcc gcggttcgcg gcgggctgcg ggtccgtggt ggcgccgccg
     4681 tagttgatgg agaccgacag gttcaggtag aagaacccgt cctggtagag caggccgaag
     4741 gcgaactcgt ggaagttccc gccgaagggc caggtcgcca cccgccggta ctggtcggtg
     4801 acctcgtcgc cgttggtgtc gttgagctcg gtcagttcgt gtttctggga gacgtagagc
     4861 ttgccgtcga cgtgcttgat ccccatcggc tccctcaggc cggaggccac cttcttggcg
     4921 gtcaccttgt cgggcccggt gctgccggtg acgttgctca gcaggtagac ctctcccgcg
     4981 gtgttgttgc tgcctcccca ggtggccacg gccaggcgtc cgtcagggag ccagtccatc
     5041 gcggagacct gcggctcgaa gccgttcggc cggaggttgg tgagggtgta gttgggatgc
     5101 acaccggtca gcggcaggcc gtctcccggg gagtcggtgc ctccctcgca ctccttgcgg
     5161 cccggagccg tcacgcgcac gacaccggcg tcggtgctga gcaccgagtt cggcacgacg
     5221 ctgaaggccg aggcgcccgg cggtttccag gacagcgtga gctgctgtcc gccgtcgcgc
     5281 tcgaagtgct cgatgcgcag cgagtgagag ccggccgtca ggtcgaccgt ggcgtccttg
     5341 gggtccggtc cgtgcagacc gtcgtggttg atgaccagtt ggtcgtcgat ccagagccgg
     5401 gacccgtcgt cgctggtgag ccggaaggtg tagccgcccg actgtgcggc gccgaggttg
     5461 ccgaggacgt gggtgacgaa gtgggactcc aggccgaagt cgtcggccga ggaccagtcg
     5521 atcacgggca tcagcttgtc gacgttcggc gtctggcccg ccttcagcgt gcagatctcg
     5581 ttcagcgggg cttgcacgtc gaagacgcgc agcgtgacac ccggttcctg cggggggaga
     5641 gccgcggcct ccgagtcgtc cgccggagac ggggacgacg acaggccgac ggccagtaag
     5701 gaagcgatga tcgttccggc caggcgtctg cccagccgac gggggtacag ccgtggatac
     5761 acgtgacctc ctgacggtcc ctcgggcatg aggaactcga tcgggtaagt gggagatcca
     5821 ccgctgccgg gacgcgccgt cgtcccggat acggaggggt gcatacgtgg gcccaagggg
     5881 ggcgcacggc gtcgcaccgg acacagtagg gacttccacc ggggccgtcc acgctttgtc
     5941 atgagcgagg gaaaagttct ggccggtcga gacgtcctcc gcgccgcggc cgggcaccac
     6001 cgtcggaagc cggcgttcgg gtggtcggaa aagcgcaagt ctcgtacgcg gaccacagga
     6061 ctacgtcttt ggtaccggac cacccgggcc cgcggtccga tccgccgcac cccgactccg
     6121 catagcgtca caccatgcgt ataggactac tcggcaccgg caatgtcgcc cgagcactgg
     6181 cccatggctg gagtaccgcg ggacacgacg tgctcctcgg ttcacgccgg cccaaggaac
     6241 gaaccgacct cggtctcccc gtggcgagcc tgagcgagac ggcagcccac gcggaggcac
     6301 tggtcaacgc cactccgggg gccgtctccg tggaactgct gcactccatc ggggcgtctg
     6361 cactggccgg caccctgctg atcgatgtcg gggtcggcct ctccgacgac ttcaccgagc
     6421 tctcgcaccc caacagcagc ctgggtgaac agatccaggc gtccttcccc ctgacgcccg
     6481 tcgtcaagac gctctgcacc atggactcca ccgtgatgac cgccccggac ggtctcgacg
     6541 gtccgagcac cgtcttcctc tccggcgacg acgccgaagc gaagcggacc accggccggc
     6601 tgctcaccga cctcggctgg cctccgtcgt cccagctcga catcggaggc atcgtcaccg
     6661 cacgcgggca ggagcacttc gccctgctct tcatgggtat cgcgggcggt ctggggggcc
     6721 acacgttcaa catcaacgtg gtcaccccgt cttccgccca ggtgtagtga tcacgaccgc
     6781 tgtcagcgcc gatcgggcga ggccgcgcgc cttcgcccca caggcctcga ggtgtggagc
     6841 ctcaaggcct atggggcggg gtccggcccg gggagtgacc cacggcagcc aggtcagcgt
     6901 ccggccgtca cgaaggccgg gtcagcggcg gcttcggcgg cgtgcgagtc ggtggaatgc
     6961 cttcggcccg ggggtcggtg cgggcagtgc tcccgagacc gcgtcggcca gcagggtccc
     7021 gaccgtctcc gccgcgcaga cgcggttggc gccgatgcct ccggaaggcc cccgtttgat
     7081 ccagcccacc acgtacgtcc cggcccttcc gatcacccgg ccgcgctcgt gcgggaccgt
     7141 cccggtcgcc tcgtcgtacg gcagtcccgg ctgcggcact ccgcggtagc cgatcgcccg
     7201 cagcgccatg ccggccggaa tctccagctc accggctccg ccggcgacgc gtacggcgcg
     7261 catgtgcgcg tccccgcaca cttccacggg cgtggacagg aaacggaaga cgatgcgacg
     7321 ccgccgtcct gtcgcgctcg gtggcgcgga ccagtcgacg gtctcccgcg ccacgccccg
     7381 cagcaccgcc gccttgtcct tcggtccggc ggcgtcgatc accgccccga tgcgcggatc
     7441 gtgggcgtcc acgaccaggt ccacctcggg aaggtgtttc agggcgagga gttcgggccg
     7501 ggtgcacgcc gcgtcgtccg gacctcgccg tccgagcagc accacctcgc gcaccttgct
     7561 gtgccgcagc tccgccaggg cgtggcgcgc gatccccgtg tcggccagtg cctccgggtc
     7621 ggtgaccagg atgcgggcga cgtcgagggc gacgttgccg ttgccgatca cgacgacacg
     7681 ttcgctcgag agatcgacgg cgtccggtgc gacgtccgga tgcgcgttgt accaggcgac
     7741 gaaggtggtc gcggacaggc tgcccgtacg gtcctcgccg ggtatgccga gccgccggtc
     7801 cgtggcagcg cccacggcgt agatcaccgc gtcgtggtgt gccgcgatct cctcggtcgt
     7861 gacgtctccg cccacctcga ggccgaggtg catgcgcacg cgcgggtggg tgtggaagcg
     7921 ggcgaacgta tcgccgatct tcttggtcgc cgggtggtcc ggggccacac cgtagcggat
     7981 caggccaccg gcggccggaa gccggtcgat gagcgtcacc tcggcccggg tgtgcagcag
     8041 caggtcctca gcggcgtaca tgccggccgg cccggtaccc acgatcgcga cccgcagtgg
     8101 cccgaagtcc ggcggcagta cgcggtcgaa ggccggctcg ccccaggaat ggaagttcgg
     8161 cccggaggcg ttcgcccctg ccccctccgc ctcttcctcg gcctgctcga agtaggccgc
     8221 gttcatgtcg gcgtactccc gctgaccggc ggtcaggctc tcgaccggga agatggcatc
     8281 caccgggcac gcgtcggcgc aggcgccgca gtcgatgcag gtcttcgggt cgatgtgcag
     8341 catctcggtg ctgccgaacg cctgctcctc gggtgtgggg cgaatgcagt tgaccgggca
     8401 gacggacacg cacgtggcgt cgctgcaaca ggtctgggtg atcgcgaagg ccatgtcgtc
     8461 cgctcggctc cgggtcgtca gatcaggttg gcgcgctggt agaagaacag cgcgggcttg
     8521 gtgagcaggc cgaccgaggt caggaactcc atgagacccg agcagctcga ccgcatcatc
     8581 gacttgtggt gctcgttggc cttcgcctcg cggagggcgc gctcctcgtc caggccggcg
     8641 ttcgcgtaga ccttccggtt caccatgctg gtgacgatga cgtaggccgc cacggcgatc
     8701 aggagcgact ggatctggcg ccgtgtccgt ccggcacgcg cgaggtgcct gcgcgtctcg
     8761 tcacgggcga acttcatgtg ccgtgactcc tcgacgacat ggatgttgtt gatggtccgg
     8821 acgaacggca cgacccgttc gtcgcgcatc cagtcgcgct gcatgacgtc gaggacctcc
     8881 tcggcgacca ggatcgccgc gtacgcggcc tcaccgaacg cgacggtctt gaagagcctg
     8941 ccgagttcga cggctgtccg gtgcggccgg taggccggcg cctgaagctt cttcgcaccc
     9001 cgcgcgaaca tgatcgagtg acggcactcg tcggcgatct ccgtgagcgc ccactggaac
     9061 gtgtcgctgg tcgggtcctt cgcgtagatg tcccgcagca ccatctgctg caggatcatc
     9121 tcgaaccata tgccggtgct cgccaccgac gccgcctcct ggcgcgtcag tgccttgcgc
     9181 tgcgcttcgg tcatctcgtt ccagtacgcc gtcccgtaca gcgtgctcca ctcggggctg
     9241 gcgccgtgga actccgtgtc gagcggcgtc tcccagtcga cctcggtgag cgggtcgtac
     9301 gagagctgcg cggacgagtc gagcaggcgc cgggcgatgc cgtcgtccgg cgtgcggctc
     9361 ttggtcctgg ggcgcgaaat gttgagggcc atgtcgggac tcctcgagtc gggtccgggg
     9421 gttgcctcgt tctcggctgc cattactggc ggtaacagag ccttgttgac ggactttata
     9481 gcaagagacg tcgtgtgcac acccccgaaa ggacagtcgg ccgagccggc acgtcctgcg
     9541 cggcggccga cccgccccga cggatccgcg cacgcacgtg gttagggacc aagtgcccgc
     9601 cccggcgcag cggatgcgcc cgcccgtgcc cctctggccg ggtcgggtcg tgccacgccg
     9661 cccggcagga tgaaccggtc caactcgccc gagccggccg gaaggaacgc gccggtgacc
     9721 gtgcgcggtc cgcttcgttc atccgggcat gagagcgaag cctgacaaag cggacgcctg
     9781 tcgtgtctac gcgcagcccc accgggcagt gtctacgcgc agccccaccg ggcagtgcgg
     9841 aagcagggcc gggcccgacc cgcggacacc gtgaacgggt cggcactgcc gtatccgagc
     9901 ggctggttct gcgtgggcct ggccgaccgc cggcgcccgg gcacggtgca cagggtggcg
     9961 ttcatattcc gcggcacggg cgggtcctgt cgcgtccggg ctaagccagc agcagcggca
    10021 tgtcccagtc ggccggtgtg ccgtccaccg cgtacgagtc cagggcgagc gcgacgccgg
    10081 cggccccgtc gaggtagccg gatacgtcgg acccgaacgg caccttcgtc atcgtgaaac
    10141 gcagcccgaa aggcagtgcc ggatcgaagg cggcgacgag gtcggcggcg atgtcgtcgc
    10201 gcagttcggc cagccggggg tcctgccacc gttcgtcgag tcggccgagc aagtgcaggg
    10261 ccccggccca gccgtggcac agcgcatggt cgtcgatgcc ccaggccgac cggggaagga
    10321 cgagcagccg atccaccgag gcgcgggcga ggtccgtgaa atccgtccgg ccgagcgcct
    10381 gtccggccag ctgcagagcg cgggaaaccc cgggagtccc gtagcaccag gccggccact
    10441 tggcgcttcc gtcgtaggcg gcaggccccc gttgccactg ggcgaaggag aggtagcccg
    10501 gccagaacag gccgtgctcg tccgtcaccg cccaggtccg caacagtgcg gccgtcgcct
    10561 ccatggcctc ctgctgcccc ggtacgcgca ccttctgctc ccacgccagg gccatcaggg
    10621 cgagcggccc ggcgacgccg tgcgagaggc ccaggttgag atggccaccg gggaacgcgg
    10681 cctcggagcc gacccgtggc gcgtccaggg cccaccagcg cggcacgtcc gcgccttggt
    10741 gctccacggt gccgagcgag aggcgcacga ggtagtcgag caccgccgtc agcggctcct
    10801 cacagctctc cgcccgggcc agcaggtaac ggccgacacc ggtcagcccg cggaccacct
    10861 cgtagtgccc gatcgtcggc agcggccggt cctcgacggg cggcaggacc gtccgtacga
    10921 gatcgcgctg gtaggtgtcg aagcgctgga gcgcggagac gtagcccccg gtggtgcggt
    10981 gagcgaggag cacggcgaac gccagggccc ccggaccctt gaagatcccg cccgcggcgc
    11041 cgggccggcc cgagacggcg cgggttcccg ccgtgagata cgcgtgggcg cgtggcacct
    11101 gccgcgtcgt gtcccgggcc gctcccgcga acgcgagcgc cagcccgggg ctgccgctgc
    11161 cgagggtgag ctcggcccag atcggctcgt ccaccccgtc gtccgcggcc tgggcgggga
    11221 tacgcgtggc cgccatcgtg gcggcgggat cggcgagccg gtccaggatc tcggcggaga
    11281 cggcggcagc acgctcccgg aggtcccggc cggaccggcc gatcgggtgc tcccgtgtcc
    11341 cgccgtcggt ggtcccgttc atcgtgtgct cccgcgtccc gccccggtgc tcccgctcat
    11401 cgtccgctcc ctccctcgtg ccgcaggcgc ccggcatggg tccgcaccgc gccccgcaga
    11461 accgcgtacc cgcgcgtctc ggccgcccgg tcgatgccga acaggcggtt gtgccgcatg
    11521 tgcagcagcg acagcagggc ctcgtcgcgg tcggcctccg gagcggacag gagcaactgc
    11581 ccgtacgcgc gcggctcggg cgactcggac cacagcgcgc cgagggacgg cgccccgagt
    11641 gcttccgcgg ccgacgacac cgcgttcccc ggtctgatca gccggtcggc cacggcgcgg
    11701 tgccgctggt agacctcgtg ctccggggtc ttggtgaaca tccggtcgac ccagccgcac
    11761 cagtcccagt ccccgaggga ctccagaagg accgcgtgcc cgagcccggc gagcacggcg
    11821 gcggggagcg cccgcgcgac gccccgcaga gcgcgcaact gcacgagcgc cgacaggctg
    11881 tccgtgcgga agaaccgctc ggccgcctcc tgcagggcct cgcctccgta ccggtcgctc
    11941 tcgggccggt acgtgtcgag ggtcatcgtg cgcagggccc cgcgctcgac gagggcccgt
    12001 gacacacggc tgaccacggg cagcacccgg ccgttcagcg ccgcgggatc gccgtggaaa
    12061 cgcagccgca gatgcggctc gggatcctgg tagcgcagga agaaccagcg gtcgacctcg
    12121 tcctcgacct cggcgagcac ggccggaaga tgatcgacga gcagagcgtc gtgggccgac
    12181 ggctccgcgt accacttgac gaacagccag tcctcgcccg gcagatggat ccgggccggg
    12241 gcaggccgga ccggcagggc ggtccgcgcc cgcgcggtgt cttccggtgc cgtacgcccg
    12301 gcgggccgcc gcgcccccgc gaggggcacc acgatctccg tgctgtgccc gccgttccag
    12361 ccgagcccgg cgccgtcggc cgtcaggtcc tcatagagga cgaactgggg atgtgcggcg
    12421 gtcagttcgg cgcgcagcag gctccggtcc caggactcgc gcaggtcgac ggggtacatc
    12481 tggtcgttgc gcgcgatctg gagccggtcc gggacggcga ggcgccgtcg ccacgcgtcg
    12541 agaccctgct cccacacctc ggcgccctgt gcccgggccg cgtcgcgcag ccggcggccc
    12601 ggcagccagc gccccggcat cgccaccacc cgcccgtacc gaatgcgcgg caggtagggc
    12661 agggcgtcat ggcccgccca gtcccagccc gaccacattc ggggccgggc cgccgcgaga
    12721 tccatgagga accgggccac cggcggagcc tgtgtgtcca gagccagcat gtgcggcagc
    12781 accggacgga ccggccggcc gctctccgga cacagcagcc gcagcccgtc ggagccggcg
    12841 gcgacgacca gcgagcgcca gtcgagacag caggggtcgt cccggtcgtc ggcgatgccg
    12901 acggggatgc ggtacggcag cagccggggc acctggacga tgttgaggcc gcgcggctcg
    12961 tggggcatca actccacctg ggccgcgatc accgcgtcgt cggggtcgac ggcggtgtcg
    13021 gcggccagcc gggcgagttc gccggtgagc cccgcagccg ccgcgaaccg gcccgcggtg
    13081 gcgcccgccg tccaggcccc gatgtgcgga ctgccgagca gccggaagtc gccgcggtcc
    13141 agtgcggcgg tgctctcggc gagcacctgg aagcagagtt cgaggctgcg cggcggcgcg
    13201 gccgcgggat cgtgcccggc gacttcggca agtcgcccca cgatgtcgtc ggtcagcacc
    13261 aggtcgccgc cggacaggac ggcctcctgc agcagctcgc cgatcatcgc gcgcctgggg
    13321 ccgtccgcct cgtctccggg gccgttgcgt gcgtacacgg gctccgcacc gtactcgggg
    13381 ggcaggccga gtccgcggtg cgggtcgacc agctcgccca acggcacggc gcaggcggtg
    13441 ccgtagcgtt cgatgaagcg ttcgcggtag tcccgcatgt acgccagcgt cgtccactcc
    13501 ggggtgatcg cccagatcgc ggccgcatac cggcacacct cctggccgac tgcctccggt
    13561 acgacgaact cgccgggtat gtgcagatcc acgtgcaggg gtggccgggc gtgcgcgtcg
    13621 ccgtccgtgc cggggacgtc gaggcggcgg acctcgtcca ggagctgctg ccaggagtcg
    13681 ccgcccagcc ccggggggtc ctcctggtgc cgtgcacagg ccgcccggac gtcccgcagc
    13741 gcctgcgcgt cgttgggaag cgccgcctcc aggaccgcct cgatgccgtc gagcagctcg
    13801 gcgtcgatgc ggtgcggggt gatcgaggtg agcaggaagc cgtgttgcac gagtccggcc
    13861 agctgacggt cgagccgttc ggcgtccagc gtgggaaagc gttccgtcag cgtgacgagc
    13921 agctcggcat acggcaccgg agtccgcgcc cgttcgcgca cggcgccgac cagggcgttg
    13981 tcgcgcacgg actgctcctg tccgccggtg cgcagataca gccgcccgtc ccgcaggaag
    14041 cacaggtcat tgattacgac gtccacgcgc ctgcggacgg agggctcggc gagccaggcc
    14101 agtacccggc ggcgcagcca cgccccgtcg agccggaccg cgacctcgcc ggtgcccggc
    14161 tccgccttgg ccgcggaacc gaaccgggcg gtgccgacac ccgcgaacag gccgaacggc
    14221 gtggggcgcg ccccggcgcg gcgggcgtac cgcgtcaggg tccgcgcggc gctcagggtc
    14281 cgcttgcggc ccagcgcggt tgcgccttcg tcactggcca ggccggccag gctgcgggcc
    14341 agcgagccgc tggcgacccg gaccgcctgg ccgagcaggg gatcggaggc gagctgccgc
    14401 gccccggaaa ccggctcggc ggcgtcgacc gtggccagag cggcgccgcg tggccgactc
    14461 gccatgcgga cgagcaccgg ctcccgtacc tcgaatgctg acgttgcttg ctgggcttcg
    14521 gactccgccg ccacgtgtgt gctcctcgcc gtcgtacgga agagcggggc ggttccggga
    14581 ccgccccgct cggaagagcc ccgagggggc ctcagtccgt cagcaacaga tggggcagcg
    14641 cgtgccgatc gcgtagctgc tgggcgaggt gaaggtgccc tggccgaacg actcggcctg
    14701 ctccgggaga tcggagacgc gcaggtccag gtcgaggtcg agctcggggg cttcgtggga
    14761 cagaacgatc tcggtacgca tgcttctccc ttgggtggtg gggttgcacg gactcgaaca
    14821 tccagggccc cggtcgaggc ctggacatgc gcaacctttg ctcacgccac tgacagtcgg
    14881 tagacgaaaa cgagccattg atcaagggcc gacagctgcc gaggacgggg cgcggtgaag
    14941 gggtccgcgc gtgtgaaagg cggcagcgcc gcctgaacca cccgagtgcc ccgcccttcg
    15001 gcccaggtca gggggcatga gccgaccagc cgacgatcct ccccgacagt tcgacccgca
    15061 ctcctgcggc acggccgatg cccgcaccga ccgccgtgcc agatcggcca gttcagcgcc
    15121 tcgggcgcac catcgactac cgtctccgcc tcagtctcgg gagtggccca ggggacgcgg
    15181 tgacggccgg cgtcgaacta ctgggcagcg gcctggccat cgaaggtgct ccggccctcg
    15241 aagtccgtag ggccttgcac acagcgggca cccagctgct ggaccgccgg cgggctcacc
    15301 tgggcagcgc gctccggctg ggtgaggagg agctgacccg gctccgtcac gtggccgggt
    15361 tctatgaggc cgtctaccgc aatggcgtct tctcccggcg ccgtaacctg ctcaccctgg
    15421 ccgacgcacg caccaccctg gctcatctga ccgcggcggt gcccgcgtac gtggtggagg
    15481 acatcgcaga gcagttcgag cttgctgaac ggcccttcgc acccttcagg cagctaccgg
    15541 aggggcagcg ggtgtgcggg ccggtgttcg ccggcagcgg cgacctgggc ggagccgacg
    15601 cggacttcat cgtcggcggg ctgctcggcg gcgcgatgac cttcgtcgag ccaggtgacc
    15661 gtcacggtga ggagcaggcc gggggagagg gccacgaggt ggcgcttgcg ccggtggccg
    15721 ctgccggagg cagccactca cgcggcgggg tgctccggca gggcgagaaa gtccggccag
    15781 gagatctcgc ggccgatgaa tcgcggctgc tcgaacggcc agtcggtggc gatccactgc
    15841 ggcaccagcg cgtcgagggc ctgctcgacc ttgctgccca ccagatcgtc caccacccac
    15901 catgagatgt cgccgtccgc gccgaccctc tccggcgggt cgatgtagac gcagccgagc
    15961 agggctgtct ccgccgagtc gaacagcgcg tagttgaagg actggtgtgc ggcgatctcc
    16021 ttctcgtgcc gcaacaggtc ggcccggtcc gcctcgaagg tcatggtggc cgcgggccag
    16081 ccccaggccg ggccgtagat ggtccacagc cgctcgcgcg agcccatcac agccggatag
    16141 tcgagcgggg tgtccgcctc ccggatcggc cgcaggtgat gaccaccacc cggcagcggg
    16201 accagcacgg ggtggacgaa gtcatcggga agccagctca tggggcccga ccgtagcagc
    16261 gcgcggccgt tcgatcccct gggtttcccc cgaagaccgc cgagccctac caagctgccg
    16321 tcccctcgcc ccgctgctga cgcgggcgtg actcttcgat gccgacgtcc ggcagcagcc
    16381 tgcctcgctg ccgcggtcag tacgagtcga cgctgatcga gtaaccggca tccgtgctga
    16441 ggtcgggacg gcttccatgg ccctcttccg cgagaagctc ggcggtgagg aagacgaccc
    16501 gcagactcat cgtcttcctg acgaagctca ggtcgtcggg cgcagcgtcg gggtccgggc
    16561 tccatccgtc ctgttgcgct gctgtccggt aatgcgccgc cacttcggcc cgcgtgccgg
    16621 gaaaggcgta cgtccgctct gcgtacaccg tgacgtcgcc gctgtcggcc cagcagccgg
    16681 cgtcgacctc ctcgaagccc cgggcgacgg tggctctgtc gggccgggag tcaaggatgc
    16741 cgagggccgc catctcctcg acccgggcgt cggccccctc gcagtcccgg gcgagatccg
    16801 tcagcgtgca gccggtgagt gccgaggccg cgaacatggt cgccaggagg agagagacag
    16861 gtcggacgcg gacgcaggct gctgttccca gggacaaggc gggctccagg gcgtagtccg
    16921 aggcagagga cgagtcactc tcggcacggc cggttctacc agaagccgct accgtcgcat
    16981 catccagggc gtgcgccagc cggtcgcctg gccgttgcaa cgaggtaggt agcgagatga
    17041 cgagcggcgg atcggatgtc gacgcagcct tggtggccct ggcgtgggaa aggctgcagt
    17101 cggagacacc gccggccgcg gtctgcggtg aactcgccgc gcggacgcca tgctggtggg
    17161 acgcggtgct ggccgtcggc cgggcgatgg ggattccgga gtcggagctg ctgcggcgcc
    17221 tgcacggcac gccgcaacag gtgcggagcg agttccgccc tggcgaggag gagctgtacg
    17281 gcgacctgat ggcggtgctc ggggtgttcg acatccccag acagctcgac gagcgggagt
    17341 cggtgatcgc ggagagtctg cggaccgcga tgcgtgccat ggggggtgtg gcgagcggcc
    17401 acggcctcgg tctctcacgc cgcctcgtca cgggcgagtt ggagagcgtc ttccgttcgc
    17461 ttgcacgttc cggtccgcgg gccgaccgcg gtcggcccgc ggagttctgg ggagcccttg
    17521 tggccgccgg tgaactactc gatccagcgg acggagacga gcgggggacc gtggcacagg
    17581 cgctcgccga gtgccggctg cacctggcca actgcgcccg ctaggcgacg ggcaggtggg
    17641 aagaggccgc gcgggcccag gcttgcatcc tgcgctcgct gcaccttctg gccatggtgc
    17701 aggagttcgg ctccacctgc ctggtcgccc gggccgagga cggcatccgc gggtacgtct
    17761 tcgggttcgt caccccgggc ggcaccgggt acgtgcatct gatcgccacg cgggacgatg
    17821 cccgtggtac cggtctcggg cgtcgcctgt acacggcgtt cgctgaagca gcggaacgcc
    17881 acggtgcacg gacgttgaag gcgatcacgt cggtcgggaa caccggctcg gtcgccttcc
    17941 accgcagcct cggcttcgac gcgacgatcg tcgacggcta cgacggcccc ggccgggcca
    18001 tggccgtctt ccgccgagat ctgccgctcg aattcccgcg gccctgaccc gcccaccatc
    18061 accggtgctc gtccaccaga tcgtcagcgg tgagatgcgc ttcgctcgta gcaaagcttg
    18121 gctgcccgcc gaggtgagcc cggtgacagc tggtcgacgg catacggtcc cgggttcaca
    18181 ccggtgtccc gtggcgggac aggccccgtc ctcatcgctg cgatcaacga gcggttgtgg
    18241 cgtactgatc cgaagccaac tcgaacaccc gcactcgccg gtcgcaggag gggttcacgg
    18301 tctcacggac cggatgcatg cccagtttgg tcatgatccg ttcggaggcg ttgttgccca
    18361 cttgagcgat gctgacgatc cgttccagcc ctcgctcctg gaacccgaac cgtacagctg
    18421 ccgcagcggc ctcggtggcc agtccctgcc cccagtggga acgtcccagc cgccagccga
    18481 cctcgaccgc cggcagtacc tccggcagga agttgggcac cgagagaccg gtgaacccgg
    18541 ccagttcgcc agtggaccgg atctccacgg cgaacaggcc gaagccttcc gactcccact
    18601 cgctctccca tgcctggacc ctgcggcgag tctgctgttc gtcaaggacg ctgccgtcac
    18661 ggatccaccg catgacctcg ggatcggcat tgacggcggc catgggggca acgtcctcct
    18721 cgcgccagcg acgcaggatc aaacggggag tctcaagagt gaccatcgga tcattctgga
    18781 tcgcagatgg gctctccgcc atcctcacca ggaagttccg gtgcacgctg tcgaggagag
    18841 gccgacggat ccggtcggcg gctgtgcccg ggtcccagtc gtgcggcagg gccgtgccgg
    18901 tacgggggac agcctgcggc gcctggcgcc gagggcgagg gctagagtcg tgggtgatcc
    18961 ttgtcattga ggagggggct cggaggatga gcgggacagt gacagccgtc agcagcaacg
    19021 gcgagtacac gttcaccaag cccaaccggg acagcatcac gctgctcgcc gggcttggtg
    19081 tggagggcga cgtgcatgcc ggcgtgacgg tcaagcaccg ctcacgcgtc gcgcaggacc
    19141 ccacccagcc gaacctgcgc caggtgcacc tcatccatga agagctcttc gccgaagtcc
    19201 gtgcggcggg attcgaggtg ctgcccggtg acctcggcga gaacatcacc accagcggta
    19261 tcgatctgct gggcctgccg gtcggcacct tgctgcgcat cggcgacgag gcggtgctgg
    19321 aggtgaccgg cctgcggaac ccctgcctgc agatcgacaa cttccaggac gggctgctca
    19381 agcaggtcgt cggccgtgac gaagccggca acatcgtgcg caaggcagga atcatgagca
    19441 tcgtgaagaa cggcggcgtg gtgcgcccgg gcgacacgat caaagtggag cttcccggcg
    19501 ggccacaccg gcctctggag cgagtctgac gtctccaccg ggccggccat gacgcgccat
    19561 cgaccgcccg ggttcttgtg gcgtgagcat caagcaggcc cgcgcggccg tctcacaccc
    19621 agaggccgat tcgtccctac gtcgctgtcg cccaaccggt aacggggaag gtccggcccg
    19681 tcagggcgtg agagtaccgt cgagggtgga acggcagtcg atgacctggt ccacgccgac
    19741 gagtcgcagg acgcgcagga cggcgtccgt gggggcggcc aagcgcagcc agccaccgga
    19801 cgcggcgatg tcctggtggg cggcgatgag gatgttgatg ccgctggagt ccatgaaggt
    19861 gacctggcgc atgtcgagca cgatgcgggg ccggtccgtg cccgccacgt ccagggcctg
    19921 cctgagctgc cctccggtgt cgttgtcgat ctccccggtg agggccagga cgcggatgcc
    19981 gtcgatgacg gtggatacgg cggacagtct gtccgtctga tcggggcgtc cgctgtccgt
    20041 cgtctgttcc tgggccatgt gggggatcct tgcacatccc cgcaccgcac ctgacggggc
    20101 ctccgctgcc gtgcttcacg gaagacggtc ctgccagaag accggtgccg gatattggca
    20161 ggcatgggcc gaccgtgcgt gggtatgcgc gcgggcatga acggggtagc gaaggtggcc
    20221 gcagtggaag caacgcctgt gggtgaggac ggcccggcgc cgtatgagca ggtcctccag
    20281 acgacgaccg ccctggacgg tgacagcgcg gacatcggcc gagcccgcca cgtggcagcg
    20341 gccttcctgt cccgggttca ggccgagcac gggctgccgg tgtcccagcg ggcgatggag
    20401 gtgacccagc tggtgatcag cgagctcgtc accaactccc gcaagtacgc gccgggcccg
    20461 atcctggtgg atctgaggat caccggtgac atggtcgagg tggcggtgtg ggactcggac
    20521 tccgccctgc cgatggcacg ggctgccgat gccggccggg tcggccagca cgggctggag
    20581 atcgtcatgg cggtggccca gggcttcgaa gcccgccggg agccggtcgg caagcggatc
    20641 accgtccgca tcgctctgtt cgacgacccc ggcggcgccg tcagcggccg aaccctcctc
    20701 tgaccctccg gctctcgtcc gccaagcgct gtgtccgtga aggtacgccg gttggtgttc
    20761 gcgccggaca ccactcggcc ggccctcgtg caccctcagc gggcgggagg gtcgtcgtcc
    20821 ccgcctgctc agctctgccg agggggactt cgtgtccaga cggcgacgac gtgcccggcc
    20881 ggacccagcc aaccggtcac ccgtcggtcc gtgcccccgt caagtgagcg gaagccggca
    20941 ggcagggacc tcaaagacca gttcgagacc atcctcctca tcccactgct ctccgacctg
    21001 gacgaagccg aagcccgaga tcgtggccag ggacgccacg ttgtcggggc cgatcgtcgc
    21061 ccgcacggtc gtgaccgtgg gctccgctcc tgccaggcga agcaactcga ccagcgcgga
    21121 ccggccatat ccctggcgac ggaagtcggg ggcgacggaa tagccgatct cgaccatgcc
    21181 ggcctcatcg ggaggtccgt ggaacccggc atgtccgacg acgagacctc cgtcgccgac
    21241 gaccgcctgc cgcaccatcc accgcgcatg gccgggatcg gcggccatct ggtcgagccg
    21301 gaactgccac agccaccgtg cgctgtcggt catgaagtac tcggtcagcg aaattccggc
    21361 ctccctgccg gccccggaca ggtctccagc cagcaaggcg gacatcgcac caccggccag
    21421 ctcgacaaaa cggacgcgtt tcgggctccg caggagcggt ctccggagat cggcttcatc
    21481 tgtcacctgc ggatgctcgc tgacgaaccc gaaacatgtc caacgatttc gaagcaggcc
    21541 gccgaccagc tcgcgccact gttcaccgtc accacctcac tgcggtgacc attcctggtc
    21601 acggcgccaa ctagccctgt accagggtgc gcaggacgca gaattcgttc ccctcggggt
    21661 ctgccatgac cacccagttg cggtccgctc cttggcccac gtccgccctg gtggcgccga
    21721 ggccgagcag tctggacacc tcgttctcgg tgctgcggtc gatcggactg acgtcgagat
    21781 gcagccggtt cttgacggtt ttgacctccg gcacgcggat gaacacgagg gtgggcggca
    21841 tctggcgggc ccggacctcc tcgacggtcg gcacccagga gccgatctcg acctggcgct
    21901 cccgcggggc agagcgcacg cgccggccga tcagttgccc cgcgtattcc gtgtcatctc
    21961 gactgcctcg gtgatggcgc gttgcctgag atcgccgaac agctgcatcg tgacggcggc
    22021 caggacgtcg tccccgccga cagtacgccc gtccccgcag cgggtggaca gggcgaggag
    22081 ggggtccttg agcagcggga ccggggccgg ctcgcccggc accaccggac tgaccgtccc
    22141 gaaccgcttg accccgccct cgcggacgac cttcgccgcg tcccgggcca ggcccgtcag
    22201 gaacacgctc gcgattccgt ccaggtcgcg gaccatcgcc gggaccgccc tcaccccccg
    22261 gctctccagc agccttctca ccccggcctc gaaccggtgg gcgccggcca cacccctggg
    22321 tgtacgcgcc ccgcggcgct gacgaagaga cacgagcgca ccatcggcgt tgcgcacctc
    22381 gcccatcagg ccgtggaagg tggggctgtg caggtaccac tccgatccca cctccacctc
    22441 gatgttccgg tcgatcgccg agatgaggtc cttgggaatc agcctcttcc tggcctcctc
    22501 ggccgccgcg cttctcgcgc cgtcgatgat ctccgtcagc acggtccgcg tcaccgacgc
    22561 ggcagcccag gcggccggcc gggagacgtg caacgaggtc acgtccctga acaccgcttt
    22621 gacgagctga ggcttgaacg gcaggtcggt gacgacggaa gcggtctgcg gggcgctgcg
    22681 ctcggtgggt aggggttgtg tggtcatcga agaatggctt tctgctgtcg aaggtgtcag
    22741 tggcccgtgt gccgcaccgg gcggcgagac cacagagctc tgcggagggt gccgagccgg
    22801 cacaggggct gccgggcggt gccgccggca cacagggggc aggcggcccc gcccggatgc
    22861 tcggcgttcc ggcgaccggg cgtgcggcag ggggcgccac acgggcgatg cgctgtggtg
    22921 cgtcgccgtg ccgatcaggc gccccggtac ctgctgactg gttcacttcg ctgatgttgc
    22981 cacctgggtc tgacaacggc agctgcccca atgcggtcgc agagcaccgt cgctgcggac
    23041 gtggttggtg ttcgggcggc gcgccttcga gaagggcggt ctgagcgcgg ctcgtgggag
    23101 tcgggtcctg atcaggcgag gcgaatcctg gaggcggtcg gtgctcctca cgtggaggag
    23161 cgaggacggt ggtggtcgcg ccatgcacgt ggcgagagtc cgtacgcctg tttgaaaacc
    23221 ttgctgaagt gggaggcgtc cacgaagccc caactccgcc ccaccgcagc gatggtgcgc
    23281 gaccgcccct tcgggccggc cagctctcgc ctgcatgcgg caaggcggtg tgtacggatc
    23341 cagtctccga ggctgatgcc cgaccgggac agcaccgcgt agaggtggcg cacggagatg
    23401 ccgtgtgcgc gagcgatccg tgcggccgac agatccgggt ctgccaggtg ggcccggacg
    23461 tactgcgtga cgcgcagggt gagtgtcgcc tccagcggtc ccttggccag ttcggagttg
    23521 ccgtgttgcc acgtcaggac tgcgcggagg agctcgatgc tgggttccac cacggcgtcg
    23581 gcgtgcccgc cctggtgcag ttcgtcggtg gcggccagtt ggcagaaata gtcgaaggcg
    23641 agacgcgcga cggggttgtc ggatcccaga gtgaccgtgc tggtgtcccg tagcagtcgg
    23701 tcggggagtg cgagcgccgc gcgcgggaag cggaggaagt ggtggtcgac cccctcgtcg
    23761 aagagcagtg tgtagggaga gaccgattcg tagacggcca gctctcccgg cctcagcacg
    23821 cattcgcggt cgttctgcac caccaggctg gtgcccgaca cctggaggcc gaggaagacg
    23881 gccggctcct cgtccgcccg ggccagccgc tcagtgcgac ggacagtgac cgcggacgcc
    23941 cgcgccgtac agaacgtgag aggcccgacg tcgccgagcc cgatgcggac ggagatgtcc
    24001 tcggccgcgg gacgatgctc gatgtccacc gccaccagcg attcccacac cgcgtgccgc
    24061 accagctcct cccggtcgcg cggcggaatg aacgcagtgt ccaggaccgg gctcatgagg
    24121 cggacccgtg tccgcggcgg tcacggggtc ggcccgacca ctccacagcc cgttccctca
    24181 cggctcaccc ttcgccacgg acgcatcccg acatcattct ggtagggatc ggtgccgcgg
    24241 ttcaacggac acgacggtca cacgtaggcc cccggcccaa ggtaccgaga cccgcgcacc
    24301 acctcgcgca cggctgacaa agcatcctgc acggctgaca aagttccgcc accgcgtccg
    24361 gcctacggtc ttcaagcgat cccgagacca gatcccccgg aacggccgcg ggccggaggc
    24421 gggcgtcgcg acgggcggcc acgtccgcac gccgggcatc caggcccggc gccacctcgg
    24481 ccggaaaggt gacacgttcg tgaagcagaa ggccttcgtc gccgctgccg tgaccgcggt
    24541 gttgtgctgc gtggccggtt gcgacgtcca gacgaagcag caggccactc cggacgtcga
    24601 ggtgcgggat ctcaccgtcc gggaggagat cgagatcggg cgcgccgagg agcggctcgt
    24661 caagacctgt atggaggaaa agggccatcg ctactgggag ttgccggtgc ccggcgtgga
    24721 cgagcgcaag gccggtcgct atgtcaccga cgacgtggag tgggcgcgga agcacggtta
    24781 cggccgcggc ttcgaggaac ggtccgaaga gatccgtcgg accgacccga ccaccgtcta
    24841 tcagaacaag ctccgtccac cggagcgagc cgccttcaac cgggccctgg acggcgacta
    24901 ccgggaccga atgagcgtcg aactgcccgg cggaacgggc acggtggacg ctccccgcgg
    24961 cgggtgcgcc aacgaggcac gtgcgaagct ctacggggac tccgaggcat ggttcgtcac
    25021 ccgcaagacc atcgagggca tcctgccgct ctacggccgg gacctcatgg aggatgctcg
    25081 actcaagaag cccctcgcga aatgggcgcg gtgcatgaag gaagccggtc gccccttcgc
    25141 cgacccgggc cggctgcgcc ggaaccgcat ggtggtgacg gacgggatgc cttccgccaa
    25201 ggcacacgag ttcgacagga cactcgcggt tctcgacgcg acctgtgccc ggaagacctc
    25261 cctggccgag atcatgcgcg ccctcgaaac ctcgtaccgg gagaaggcac tccagcggta
    25321 cgaaagggaa agggacgact accgcacgat gcgcctgcac gccctgcgtg aggccgaaga
    25381 cgtcctttcc tgacagtcca ccgaatcccc ctgccacttc actcgcggcg gatccctgtc
    25441 cgcgatccct gcaccccacc caccgaagga gctcatcatg cgcaaactct ctgccgcggc
    25501 tgtcggagcg gcgcttgtcg gcatcagctt ggtaggcccc ctgcccagcg cctccgccgc
    25561 cgcggcggcc acgtgcgcgg acaactacga caacgctctc gccggctaca tgtacgccta
    25621 caacggcgcc aactgcgagg ggcaactcgg tctcgcggtc ggcaacgacc agaactgggg
    25681 cgactccgcg agcagcttcc agggctccga caccaacagg gcctcgtcag tgctcaacat
    25741 gggtaggtac tcacaggtca agttcttcgc gaacccgacc accgggtcgg ccttcaaccc
    25801 tcacatctgc ctgacccgcg ccgagggtta cgcctcgaac ctcagcgacg actacttcat
    25861 ggaggacccg gtcttcggca gcgcgaacaa cagcatcagc gctcacatct gggtcgagtt
    25921 gaccgcgtgc agcgccctcg cgcagtgacg gtgccctgac gggccgctcc gtacggcctc
    25981 ccggcatcac ctcggcccga gggacgagct tcggcggggc gagatgatgc cgcgaggaag
    26041 tcggtaaggg agtcggaaac gacttcggca ccgacggcgc tcggcttgga cgatgcggtc
    26101 caccgttcgg tcatgtctgg caccgtgagg cgaagttgtc tgctctgttc gcggtccggc
    26161 tggcgggaat gtagcgggat gtctcggtgt accaggccag cgcaccctgg ctcatgatct
    26221 tcagcttgcc gatgatgtct tggacccgtt cgagatccag ggcgggcagg ccgagatcgg
    26281 tcacgtggtc ggggaagacg cgttcaaggt ggaggaactc ggcaatccgg gctgcgatgg
    26341 cgcgggtgat ctggtgctcg gcgtccgcgc gcgagaggcc gtgcagccgg cgcagaagat
    26401 tgacggcgtt gtgggtgtca ctggctgctt cgtcccgagc cgctccgacc aggtcgttct
    26461 gaaggatcat gacgctgaac gccgtctcca gcacgtcctg ccaggcggtg gtgcggcgca
    26521 ccgaagacgg aacgtcgaag cccagagcgc cctcgatgta agccacgtcg aggatgagcc
    26581 cgatcgtctt gtaccttccc cgcaggtact cgcagtgcct cgacacctcc aggtcgatgt
    26641 ccggcgcgcg acgcagacgc tcgttgaatg cctcgagtcc gaagccgtag agggcgtcga
    26701 tgttaccggc ggcgacctga tcgtagtagg catcgctgcc ggcggcggct gtgcgccggc
    26761 agaggtccgc cagggaacgc agtaccggct gacaggagtc cgagccaccg gccggtaccg
    26821 cgctgtcccc ggcgcaccgc agcacgtgtt ccatgtccag cgacagcttc agccactgat
    26881 cgcagtccat ctgcggtgcg acgtcgtcca cgtaggtcca ccaagaccac cagtaggcga
    26941 gcaacaggcc gtagtcgaag cttgtgtacg gataacaatg gctgggccaa gcccccaccc
    27001 gcatgcccgc ataccgggcc cgtaccttcg ggtcgggaag cagacccatg tcacccatcc
    27061 acttcagtga ctgggactgg atctcttcga cgtgcggatg gcccacgacg ggcgtgccgg
    27121 tgaaagcggg aacgtccccg atgaccatgg aaaacccttc gccttctact tcccagcctt
    27181 gtccttctcg cgccgaagaa cacgaaagag cgtgcctgcg cgcgtgtcac gaccaacgat
    27241 gacagcggcg gccagccgaa aggcgcaaga atgtcggctc gtcagagtga aggtccgcag
    27301 agaccatgca cgaggggtgc actgccggag cgttcacatc ctctgtgctg gtcggcgacg
    27361 cgacactgcc gacggacgcc tcaaaaccac atgcgacctt cgcccaggca tgctgggatc
    27421 gatcgctatg aatgatcatt ccctcaacga agccgacttg ctggacagga tggagcggaa
    27481 cctggcggaa catgcctgtc acctgcaccg gagtatgacc ggtgcgaccg tcacggatgc
    27541 tggtgacctc ctggtcgcgg acagcggcct ggacgacgac acgttcaaca tcgttgcggc
    27601 ggcccgcttc accgccgccg acgccacggc acggatcacc gagactgcag ggacgctggc
    27661 tcgtaccggc cgtcgcttct cctggtgggt ggggcccgcc tcgacaccac gggacctcgg
    27721 cacccgcctg acggcggccg gtctgccgcc atccgaacgc gagacggcga tgtgggccga
    27781 actcgacgac accttgccac cgcctgccgc ccaggaactg gacatccaga gggtggccac
    27841 gcccggacag ctcgcggact acgccatggt tctcgccgcg aactgggacc cgcccgccga
    27901 aaccgtccgc cgcttcttcg cccaggcaac cccgcaggca ctggccgcgc agtgcccggc
    27961 ccggtacctc gtcggctacg tggagaaccg tccggtctgc tccgccgagg tctttcacca
    28021 cgcgggggta gccggcatct acaacatctc gaccctggcc gcccaccgcc gacgcggcta
    28081 cggcggcgcc atcacgctcg cggcactgcg ctcggcccgc gaccgaggcc accgcatcgc
    28141 ggtcctgcag gcatcagccg acggtgagcc cgtctatcac cgcctggggt tccgctcctg
    28201 cggccagttc accgaacacg ccgtcgaccc ctgaaccgcc acactccaat ggccctccgc
    28261 ccgcccttcc tgaaggtgcg ggtcacaacc actcgttgac gtggcgacag cacgacgtat
    28321 ctggaggcgg tcgaagcgcg tggatcggtg ttccagcggt attggacatt gccgagtgct
    28381 ccttggttgt ctttccggta tgacgcgaca tctccgactg cgcttatcgc tcgccacgtt
    28441 gaccgcgttg gcgctgctgg gcggcctcgc ctgtgcggtg ggtgcactca ccggcgacac
    28501 gcacgccgcc gacggggtga aggcctccga cagcgccgcc cgggtgcagg gcagcgcctc
    28561 ctccgcttcc ggcctgtcca agacgctgag agcactcgag aagtcctacg acgggcggat
    28621 cggtgcggtg ggcatcgatc tgggggacgg ccggacggtc gcgtaccgcg ccgacgaacg
    28681 cttcccgttc aattcctcgt tcaaggtgtt cgcatgcgcc gcggtgctgg acaaggcacg
    28741 caccggtgac ccggggctga tggagcaggt ggtgcgctgg gagcccgccg acatggccgg
    28801 gttgaccgcg aactccccgg agaccaccga gtacaccgac accgggatga cgcccgcgca
    28861 gctgtgccgc gccgggatca ccaagtccga cgggttcgcg ggcaatctgc ttctggagca
    28921 gatcggcggg ccgcgcgggt tgaccgcctt cttccgcgcc gtcggcgacc ggtcgagtcg
    28981 cctggaccgc ccggaacctc ggctgaccga gtgggagccc ggcggagtgc gggacaccac
    29041 cacccccgcg gcggccgcac ggaccttcac cgaactcacc accggtgaca cccttcaggg
    29101 cggtgaccgg gcgcgattgg tcggctggtt gaaggccagc gtcaccggcg ccgaccggat
    29161 caaggcgggg ctgccgaagg actggacggt cggaaacaag accggcaccg gcggcgcgag
    29221 caaccatggc accgcaagtg acctggcgat cgtctggcca cccggaacgg acgcgccgct
    29281 catcctgtcg gtgtacacca accgcaacca cgacaacacc gcacacgacg acaaggtgat
    29341 cgcatccacc gccaccgcgc tggccacggc cctcggcaga gtctgagcgg ccatccgccc
    29401 tgcacagggc aaccgggagg acccacacgc gaagccgact acggacaaca cctgacgcga
    29461 taggccgggc cgtacgggct ccagctgtcc ccaggtgtcg ggtaccgtgc cgaacggctc
    29521 cacgctccgt gctgcgtccc ccgccgggtc gccggcgagc aggcgttgcg cctctcggtc
    29581 ggtgagggct gtcgccatac agccacttcc cgacgcgcac gcgcacccga ccagcggcac
    29641 cgcgatacgg ctagtgtcga cggcatgagc gaaaactcgg agcgttccgt caccgtcgaa
    29701 cgcatcagca gcggccagtt cgtagcgacc aacgcccgtg gcggatcgat cagcttcggt
    29761 acctccccgg gtagcggtcc ggacaccgga ttcacgcctg tcgagttgtt cctggccgcg
    29821 atcggcggat gcacggctgt ggacgtcgac gtcgccaccg gccgacacgc agagccgacc
    29881 cagttctccg tgagggtcac cggcgacaag atcagcgatg acctgggcaa ccgcatgacg
    29941 aacctcgagg tcacgttcac cgtggcgttc ccggacgggg aggaagcgga gcgcgcccgt
    30001 gcgatcctgc cccgtgcggt caaggcatcc cacgaccgtc tctgcaccgt gagcagaacc
    30061 gtggagaccg gcacgcccgt gaccacgacg atcgccgacg cctgacagct gggccgcgca
    30121 gaggggtggg tggtcgagcg gccgcacttc gcggccctcg ccgagaccca cccgttttca
    30181 gttgcgtgac ctccccgaag agacgccgcg ccccatgccg ccgagacagg ctggccaagg
    30241 gatgaggcga cagagcaagg gctccgtcac ctatcccggc cggccagcca gcccggctca
    30301 ccggccaccg ccgcgcgcgg cggcgtccta cctgcgttgc cggtggggtg gcgtcggtgg
    30361 ttctcggtcc tcaggcagcc cggcccacac gcgtgcggcc attgcgtcag cctcgtcctg
    30421 cggtgtcccg gcctgcacca ggatgattcc acgggactgg tccggaaacg tgacctcccg
    30481 cattgccgta cccagcgggc gcgggcccat cggctcgtcc ggcatggcgg cctcccttcg
    30541 acggctgccg cccaggttac ggggacgtcc ccggaaaatg gggaccctcg tccggacggg
    30601 gcacaaccgc gagtcgcgac aggacggaac acgtccctga cagaccaagc gggggagcgg
    30661 gtactggcag tagccagtgt gcatgcgtga tccggtgtct gggaggagcg acggtgacgt
    30721 ccgcctcccg aacaggtgcg ccatggccgc gggcacggtt ggtggggttg ttcgtcaccg
    30781 tcaccgccaa gaccgccacc gatgtcgccg aacgcatccc ccgcgatgcc ctcgatgtac
    30841 gctgcgccgc tgcggagatc cgcgcttgaa cacggatgta ggcactggcc aggccacagg
    30901 tcgtgcccaa gccggctcgc caggtttccg cgtcgcgcag gcagcctgcg agaggtgcgc
    30961 tgcgcccgct ttgagctagg ccgcgtgctt cggctgcgca cacggtcccc agtcggcggt
    31021 ggagggcggt cactgttctt ggtgggtgaa gacgcggtcg aagcgcaggg cggccaggtc
    31081 gtggcgctgg atggcccaga cgacggtggc ggattcgatg gagtcgaggt cctcgtcctg
    31141 gcaggtccag gatgccaggt tcacccagtc ttcaccgtcc tcggcttcca acagctcgtc
    31201 cagttccgtg gccgttgcat tgccgccgag ctggatgggc ccgctcacgt ccaggagttg
    31261 cgggtcggtc gccctttgcc agacttcgcc gagcttgagg gcgaggtcct cctgctcttc
    31321 gtcgtgctct tcgccccact gtttgcgggc gaagtcgtac gagtcgagtg cggagaggcc
    31381 ggacccgacg atgccgaggg gccgctgtcg gtacgggctc tgagtcgacg agggccccgt
    31441 ggagggacgt ggcctggtcg gcgtaccggc cgggacgtag cgcacggcgt cggaggtgat
    31501 gccttcgccg ttgccgtccc actcgacaga ggcgaagaac agcagccggc cgtcgggggg
    31561 cagcggaaga tcggttgcgc gctccggcag cagagcgcag tcgatggaga agacgaaggg
    31621 gttggctggg atcggcgcgc ccaacggcag ggacggatca ccgcccctct ggcccacgca
    31681 ccgcggcccg ttgctctctg cgagatgaat cgcggggcgg acgccgcgta tgaacgcctc
    31741 gacggtctgc gggggaagat tcctggcggc ggcctgggaa cggaagagct ccgcggcgac
    31801 agcgaggttt ttctcgaaca tgcatgcacc ctaagggagg tgcgctgtcc acgacgtcgt
    31861 aaccgaggcc ctggaactgc tcgatgcggt accggagttc agggcatcag cgatggacgc
    31921 ttccagcctg ccgtcatcgg ccgtgtcgga tgaggacctc tcgcacgctg gtcaggtccg
    31981 cttccttctg cttttcgtcg tcgtaccgac cgtcctcttc ccggatcgcg acgctggtct
    32041 ccgcggtgaa gtcctggccg aaccggtaga cgcccaggca gtagtcgaaa ccggactcgc
    32101 cgaagaggtc cacgtcctcg cggcggcagt gctccgccag accgctggac acgtgccagt
    32161 gtgtgccgtc gtaccagaag acaccgcctg cgtagtgaat ggtccggccc gtcgcggagt
    32221 ccgtgaggtt cagagactcg tagttttcgg gacggtcgcg gaccagggcg accaggggtt
    32281 cggggacgcc ctcgaagaag gactcctgaa gggcgaaatc ttcctcggcg tacaggttca
    32341 gcgacgactc gtggtcgaac gtcagcagga gtacgcggcc gtcgtccgtg aagtaccaga
    32401 cggcggactg gccgccgcgg tcgttccatg ccagccggtg tgcgccggcc accgtcaccg
    32461 gtttgacctc ggcgaggtcg tccacgacgg ccgctcggtg ccgtacttct gggaggggtg
    32521 tcgccaccag ggcgtcccat atcgcgttac tcatggccgc agagtatcca ccgcctacga
    32581 caaggccgtc acggaccatc tcgccgacct ccccgtcgcc tcatctggtc agcagggcgc
    32641 gttgggcgct gctgactgca gacggacggg gcgccgctcc agcctttccg cttgaccccc
    32701 tcgtcactcg atgtggtgac atgtggtagt tgattcactg caaggagtta ctatcgctgc
    32761 accagtgcga cgcgtcagag gtgtcgtggt gtcaggcaga gccgatcgac tggtcgtcca
    32821 tcgccatggc tcacctcaag gagtgttcgt gaagctctcc ctccgtcctc gccgtgccgt
    32881 tctggcggca gcgtccggtg ccctcaccgc gctggccgcg gtggcgcttc cgggtccggc
    32941 ccatgccgag tccgtgcgtg gtccagaagt gcgtcaggcg gctgccgggt ccctcgcccc
    33001 gtgcggcttc ttccggtaca gcgtccgcga gtcccagttc gccggctacg gccactgtgg
    33061 agagacgacg gtactggtcc acgtcgacgt caggggcggt ggcagtacga acgactacca
    33121 cctctgtgtc ggccccggcg ccacccaact gcccggcgcc ggtccgaact acctcaacgc
    33181 gtactacatc ggtggagccg gttgcgctct cgggtcacgt acggggcact cggcccactg
    33241 agccgagccc gagggttgga tgggccgtcc gcaccgctgc ccacgtgagc gtcggtgatg
    33301 ttcgcgtaga tcgatcaggg tcagggcgac accggggaag gcctaggacg cgtgggcggg
    33361 gcggcgtgtg cgcaggacga gggtcgtgcc gcccgcgacg gcgagtgccg aggctcccgc
    33421 catggcggcg agcgccggag cggacgtgcc ggtgccggcg aggctggggc gggagtcttc
    33481 ggccgcccgc aggatcagtc gggtgacgtc accgggattg gtctccatga ctgcgtgcgg
    33541 cgcgtcgacc tcgacggtgg tggagtcggc acgctcggcc atgaagcgca ggttctcggt
    33601 gccgatggtg cggtcgtccg tgggtaccag gtaccaggag gggatcgtct tccaggccgc
    33661 tgcctcggtc ggctccgatc cggtgacgac cgccgcaggg cgctgggctg ccgccaggat
    33721 gtcggcctgg ctccggtcga gccggtcact caggaacacg tcgctgaact tgtcgggctt
    33781 gatgtacagg tccacatccg tgggcccgtc gccgaggggg actgcgtcca gggcggtggg
    33841 cacgggagcc tcggggtcgt ccgtgaggcg actgccgggg tatttggccg ccagttccag
    33901 cgtggtctca cccttgtccg gcgcgaagcc cgccacgtag acgagcgagg tgacgttcgg
    33961 gttcccggct gcggcgttgg tgatcacggc gccgccgtag gagtggccga ccaggacgat
    34021 gggtcccttg atcgacttga gtcgggccga gaggtaggcg gcgtcgcccg acaggctccg
    34081 cagaggattg gccgtggcga cgaccgggta accctgggac tgcagtctct cggagatctc
    34141 gtcccagccg gaggcgtccg cccaggcccc gtgcacgagc acgatcgtcg gcttgatgct
    34201 cgcgtgggac ccggtgggac cgccgctctc ggaggccgcg gtcggcatgg ccgcgaggag
    34261 gacggtcgcg gggacggcca gcgcgagggg gaggatgcgc ccggcgcggg ggtgctgcgc
    34321 tattcgcttc atgttcactt ccgtgtggag ggggctgctc gccgtcgaca ttgctccggg
    34381 cccggtcacg cgcacagccg gggaggtcca ggcgggtgac tgctctgttc actcattcga
    34441 acgaagtgaa gaaagtcggg cataccagta gatttggttc ctggggtcgc gaccgaccgc
    34501 gcgtcaccag cgccacgccg gttccggcgg ccgcctcacc gcgtgggcat cgccacacgg
    34561 gcaccgcacc gcatcgacag atccgagcgg aggaacgccg tgggaacggt cactacacag
    34621 gacggcacgg aaatcttcta caaggattgg ggaccacgcg acgcccagcc gatcgtgttc
    34681 caccacggct ggccgctgag cagcgacgac tgggacaacc agatgctcta cttcctgggc
    34741 cacggttacc gcgtcatcgc gcacgaccgg cgcggccacg ggcgttccag tcagagcgcg
    34801 tccggccacg agatggacac ctacgcagcc gacgtagcgg cgatgaccga cgcactcgac
    34861 ctgcacgacg ccgtccacat cggccactcc accggaggcg gcgaagtcgc ccggtacgtg
    34921 gcacgggcca agccgggcag ggtggcgaag gccgtgctcg tcggcgccgt gccgcccctc
    34981 atggtcaagt ccgaggccaa ccccggcggc ctgcccatcg aggtcttcga cggcttccgg
    35041 gcctcgctcg cggccaaccg tgcccagttc tacatcgacg tgccggccgg gccgttctac
    35101 gggttcaacc gtcccggcgc cgaggtgtcg cagggcgtga tcgacaactg gtggcggcag
    35161 ggcatgcgcg gcgcggccaa cgctcactac ctctgtatca aggccttctc cgagacggac
    35221 ttcaccgagg acctgaagca gatcgacgta cccgtcctgg tggcgcacgg caccgacgac
    35281 cagatcgtcc cctacgacga ctcggcaccg ctgtcggtga agctgctgcg caacggcagg
    35341 ctgaagagct acgacggcta cccgcacgga atgctgacca cgcaccccga ggtcctgaac
    35401 cccgacctcc tcgcgttcgt caaggaatag agcgggacac gctgccggtc ggcttccccg
    35461 ttcacgttcc ggggactctc ggcgcgcccc ctctcaggag gcggtgatgc ggacgaaaac
    35521 ctccggggtg acggtgcggc gctgcgcgtc gatcgacgtg atcctgcggc agcaccgcat
    35581 cgctctgggc gccgacttcc acacctatcg ccaccacgtc taccgcggcc tgaactacca
    35641 gttggcgctg ctcgggcggg accgcccgtc cacgacgatg caacttgcct gggctgtgca
    35701 cgacttgggt atgtggacgg ccgggacgtt cgactacctc gggccgtcgg ccgggctcgc
    35761 ccgtcggcac gccccggccg tgggtcgggt ggacctcccg ctcgccctca ccatgatcgc
    35821 gacgcatcac cgggtgcgct ccgtgccgga cccggaggtc gagacgttcc gtcgtgcgga
    35881 cctggtcgac gtcctgcacg gcctgccccc gacagcgtcg ggacgtgttc cggtgcgggc
    35941 cgtgacccgc gtcttcccct acctgggcct tcaccggtgc ctgctgcggc gggccgcggc
    36001 gtacgcgtgc cggcaccccc gtaaaccact gccgatggtg cgctggtgag ggcgaggagc
    36061 gcggggcgcg gccgggcccc ggcgcgcccc gccccggctc aggcgtgggc gagggcccag
    36121 tcgagtgcac ggtcggccac ttcctgccag ccctcccgga gcggccttcg cgcgacaggg
    36181 gttgtgatgg atcgcagtga tcgtgccggt gatccgggtc ctgggcttgc tcttccgatc
    36241 cgcggacagc ggcggcccgg agcgccgctg gtgccgctgg tgcgaagccg cccggagcca
    36301 ctccgggtga aatggactga acacggtgac ggccggcagc agggcgagaa gcgggggcca
    36361 aggccgccgt ccgccgcacg gcctccctct cggcccagcc gtgcacggcg tgcgtcgagg
    36421 gcgccccgcc ggcccggcgc ccgtgccggt gtgctcaccc gtctgccggg cacggccgcg
    36481 aggtgcaggc gcctgcggca gactgagggc atgggcgacc tcaagggcgc gggggcgtcg
    36541 tcgcgacggt tgccgcggcg gccgcagagc gtggcggagg cgcggcgctt cgtgcgggcc
    36601 gctgtcgacg gggtcgcgcc ggtcctggcg gacaccgtcg agctcctggt gagcgagctg
    36661 gtgacgaacg ccttgctgca tgcccggacg gacgtcgacg tgtcggcccg cgtcgagggc
    36721 ggcacggtcc atgtgcgcgt acgggatcag cggccggacc ggaagctgct gccgcaggaa
    36781 tgccccgcgt acaccggaac gggacaggga ctcgccgtcg tcggccgact ggcgtcccgg
    36841 tacggtgtcg aggcggacga ggtgagcaag accgtctggt tcgaactggg ccccgacgga
    36901 acgccgtcgc gggtggctga ctgggggtcc gccgagccgt ccgactccgg tgagcatgtg
    36961 acgctcatcg acatgccggg cgcgctgtac gtcgcgtccc agcagcagcg tcacacgctg
    37021 ctgcgcgaga cgatgctcgc cgcggccgcc ggcttcgatc tcggcgtgcc gccggaggac
    37081 ctcaccaccg cccaggacgt gagcaacgtg atcagcgcgc gggtgacggc cgccctgcgc
    37141 cgggagcc
//
