LOCUS       NZ_CP012382            26772 bp    DNA     linear   CON 26-APR-2024
DEFINITION  Streptomyces ambofaciens ATCC 23877 chromosome, complete genome.
ACCESSION   NZ_CP012382
VERSION     NZ_CP012382.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces ambofaciens ATCC 23877
  ORGANISM  Streptomyces ambofaciens ATCC 23877
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303940)
  AUTHORS   Thibessard,A., Haas,D., Gerbaud,C., Aigle,B., Lautru,S.,
            Pernodet,J.-L. and Leblond,P.
  TITLE     Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the
            spiramycin producer
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303940)
  AUTHORS   Thibessard,A., Haas,D., Gerbaud,C., Aigle,B., Lautru,S.,
            Pernodet,J.-L. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUL-2015) Faculte des Sciences et Technologies,
            Universite de Lorraine, Boulevard des Aiguillettes, Vandoeuvre les
            Nancy F-54506, France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC workbench v. 7.0.3
            Genome Coverage                   :: 114
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001267885.1-RS_2024_04_26
            Annotation Date                   :: 04/26/2024 02:57:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,510
            CDSs (total)                      :: 7,418
            Genes (coding)                    :: 7,242
            CDSs (with protein)               :: 7,242
            Genes (RNA)                       :: 92
            rRNAs                             :: 5, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 74 of 176
            Pseudo Genes (incomplete)         :: 131 of 176
            Pseudo Genes (internal stop)      :: 12 of 176
            Pseudo Genes (multiple problems)  :: 39 of 176
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:42:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6901162
            Orig. end                         :: 6927934
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012382.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26772
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="21"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26772
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26772
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16772](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16772
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(247..840)
                     /gene="idi"
                     /locus_tag="SAM23877_RS30375"
                     /old_locus_tag="SAM23877_6400"
     CDS             complement(247..840)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="idi"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020129457.1"
                     /locus_tag="SAM23877_RS30375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6400"
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_053139949.1"
                     /transl_table=11
                     /translation="MPITPATATHDASNGTADAILLELVDEDGVTIGTAEKLSAHQPPG
                     RLHRAFSVFLFDERGRLLIQQRALGKYHSPGVWSNTCCGHPYPGEAPFAAAARRTYEEL
                     GVSPSLLAEAGTVRYNHPDPASGLVEQEYNHLFVGLVQAPPRPDPEEVAETALVSPAEL
                     IERHGKDTFSAWFMTVLDAARPAVRELTGPSAGW"
     gene            complement(1136..2074)
                     /locus_tag="SAM23877_RS30380"
                     /old_locus_tag="SAM23877_6401"
     CDS             complement(1136..2074)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006133326.1"
                     /locus_tag="SAM23877_RS30380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6401"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_053139950.1"
                     /transl_table=11
                     /translation="MGAGHDHGHAHGARAGGTATAAYLGRLRVALAITLFVMVVQIVGG
                     MLADSLALVADAAHMATDALGLGMALLAVHFANRPPSDRRTFGFARAEILAALANCVLL
                     LGVGGYVLFEAVERFLTPADTEGGLTVVFGVIGLVANMVSLTLLMRGQKESLNVRGAFL
                     EVAADALGSLTVIVSALVILATGWQAADPIASLLIGLMIVPRTLRLLRETLDVLLEAAP
                     KGVDIAEVRAHILALDGVEDVHDLHAWTITSGMPVLSAHVVVSGEALSAIGHEKMLHEL
                     QGCLGDHFDVEHCTFQLEPSGHAEHEARLCH"
     misc_feature    2159..2173
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     misc_feature    complement(2358..2372)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            2545..4407
                     /locus_tag="SAM23877_RS30385"
                     /old_locus_tag="SAM23877_6402"
     CDS             2545..4407
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996269.1"
                     /locus_tag="SAM23877_RS30385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6402"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_053139952.1"
                     /transl_table=11
                     /translation="MPTAILTGQPVPGSSIESELRSLGFEVRAASGAADAELLLAQVSA
                     GERVALVDARFVGHLHSLRLGLTDPRFPLAAIPGAVTAQPAARQALTRAMARENLAVGG
                     AALGGAPARVRQGEGDAESLADRITAALDADGADVHRPELGSLVAAVPADPQARNEARQ
                     SVAAVDDEAVRLKSAVKARDGFVTTFFISPYSRYIARWCARRGLTPNQVTTASLITALI
                     AAGCAATGTRGGFVAAGVLLIASFVLDCTDGQLARYSLQYSTLGAWLDATFDRAKEYAY
                     YAGLALGAARGGDDVWALALGAMVLQTCRHVVDFSFNEANVDSTAAAANTSPTAALSDK
                     LDSVGWTVWARRMIVLPIGERWAMIAVLTAVTTPRITLYALLVGCAFAATYTTAGRVLR
                     SQTRKASRTDRAAKALADLADSGPLAEAVAAGLRKPARRLPGFTAPAVALLGGLAVVAT
                     AALTGFGGPWPVVAAVAYVLTSGLAVARPLKGALDWLVPPFLRAAEYGTVLVLAAKADV
                     NGALPAAFGLVAAVAYHHYDTVYRIRGGAGAPPQWLVRTIGGHEGRTLVITVLAVLLTA
                     TQFKLALTVLAVAVALVVLVESIRFWVAAHQGGAPAVHDEGEPA"
     gene            4404..5156
                     /locus_tag="SAM23877_RS30390"
                     /old_locus_tag="SAM23877_6403"
     CDS             4404..5156
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="SAM23877_RS30390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6403"
                     /product="phosphocholine cytidylyltransferase family
                     protein"
                     /protein_id="WP_053139954.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 7.2e-10, bitscore:
                     38.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVGPEGAEDSITVLDLTLA
                     NFAEVGLTEVGIIVGYRKEAVYDRKEALEQKYGVKLTLIDNDKAEEWNNAYSLWCGRDA
                     LKDGVILANGDTVHPVSVEKTLLAARGDGKKIILALDTVKSLAEEEMKVVVDPDKGVQR
                     ITKLMDPSEATGEYIGVTLIEGEAAVELADALKTTFERDPQLYYEDGYQELVNRGFKVD
                     VAPIGEVKWVEIDNHDDLAKGREIACQY"
     gene            5144..6205
                     /locus_tag="SAM23877_RS30395"
                     /old_locus_tag="SAM23877_6404"
     CDS             5144..6205
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="SAM23877_RS30395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6404"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_053139956.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.3e-22, bitscore: 78.9,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 4.8e-08, bitscore:
                     31.2, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRAGALDDLGCVLADERISHSGKLAVAVSG
                     GSGARLRERVAPSLPGADWFEVGGGTLDDAIKLAGAMKAGHYDAVVGLGGGKIIDCAKF
                     AAARIGLPLVAVPTNLAHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPVRF
                     VRAGIGDAVSNISAIADWELANRVKGERIDGLAAAMARQAGEAVLRHPGGVGDNDFLQV
                     LAEGLVLTGIAMSVSGDSRPASGACHEINHAFDLLFPQRTAAHGEQCGLGAAFAMYLRG
                     AHEESAHMAEVLRRHGLPVLPEEIGFTPEEFFRAVEFAPQTRPGRYTILEHLDLKTDQI
                     KDLYADYVKAIGS"
     gene            6183..6962
                     /locus_tag="SAM23877_RS30400"
                     /old_locus_tag="SAM23877_6405"
     CDS             6183..6962
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="SAM23877_RS30400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6405"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_162492134.1"
                     /transl_table=11
                     /translation="MSRPSVAELRPVVHPAGVKDRRSGEHWAGRLYMREVSLRIDRYLV
                     NTRVTPNQLTYLMTVCGVLAAPALLVPGITGAVLGVVAVQLYLLLDCVDGEVARWKKQY
                     SLGGVYLDRVGAYLTDAAVLVGLGLRAADLWGTGRIDWLWAFLGTLAALGAILIKAETD
                     LVGVARHQTGRAPVQESASEPRSSGMALARRAAGALKFHRLILGIEASLLILVLAIVDE
                     SRGDLFFTRLGTAVLAGIALLQTLLHLVSILASSRLK"
     gene            6971..7843
                     /locus_tag="SAM23877_RS30405"
                     /old_locus_tag="SAM23877_6406"
     CDS             6971..7843
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031159.1"
                     /locus_tag="SAM23877_RS30405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6406"
                     /product="glycosyltransferase"
                     /protein_id="WP_053139959.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 5.6e-12,
                     bitscore: 44.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKVGAVVITMGNRPDELRALLDSVARQDGDRVEVVVVGNGSPVPE
                     VPEGVRTVELPENLGIPGGRNVGIEAFGPGGSDVDILLFLDDDGLLARTDTAELCRQAF
                     AADDELGIISFRIADPDTGETQRRHVPRLRASDPMRSSRVTTFLGGANAVRTRVLTQVG
                     GLPDAFFYAHEETDLAWRALDAGWMIDYRSDMVLNHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPALLVPVYLGVWMLLTLLRRPSRPALKAWFGGFREGWATPCGPRRPMRWRTVWRL
                     TRLGRPPVI"
     gene            7940..8869
                     /locus_tag="SAM23877_RS30410"
                     /old_locus_tag="SAM23877_6407"
     CDS             7940..8869
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994380.1"
                     /locus_tag="SAM23877_RS30410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6407"
                     /product="ABC transporter permease"
                     /protein_id="WP_053139961.1"
                     /transl_table=11
                     /translation="MSETTHDGTVAMTKPVSPDEGLTPARLAAKYGLSVSGARPSLAEY
                     VRQLWSRRHFILAFSQAKLTAQYSQAKLGQLWQVATPLLNALVYFTIFGLILNAGKGMP
                     KDVYIPFLVTGVFVFTFTQSSAMAGVRAISGNLGLVRALHFPRASLPISFALQQLQQLL
                     ASMIVMFAVVIGFGSYPSLSWLLVVPALLLQFLFNMGLALIVARMGAKTPDLAQLMPFI
                     MRTWMYASGVMFSIPIMLEDKPTWLADVLQWNPAAVYMDLIRFALIDGYGSENLPPHVW
                     AVALGWAVVLAVGGFVYFWKAEERYGRG"
     gene            8862..9641
                     /locus_tag="SAM23877_RS30415"
                     /old_locus_tag="SAM23877_6408"
     CDS             8862..9641
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330378.1"
                     /locus_tag="SAM23877_RS30415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6408"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_053139963.1"
                     /transl_table=11
                     /translation="MAEQQQGERVPTVIADELHIVYRVNGARTGKGSATAALSRMIKRG
                     EDRGVRKVHAVRGVSFTAYRGEAIGLIGSNGSGKSTLLRAIAGLLPAERGKVYTDGQPS
                     LLGVNAALMNDLTGERNVILGGLAMGMSREQIKERYQDIVDFSGINEKGDFITLPMRTY
                     SSGMAARLRFSIAAAKDHDVLMIDEALATGDRKFQTRSEERIRELKKEAGTVFLVSHNN
                     KSIRDTCNRVLWLERGELRMDGPTDEVLKEYEKFTGK"
     misc_feature    9729..9742
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 20.42"
                     /tool="antismash"
     gene            10001..10921
                     /gene="hpnC"
                     /locus_tag="SAM23877_RS30420"
                     /old_locus_tag="SAM23877_6410"
     CDS             10001..10921
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010042802.1"
                     /locus_tag="SAM23877_RS30420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6410"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_053139965.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.3e-37, bitscore:
                     128.3, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 5.5e-40,
                     bitscore: 136.2, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATDTARAVDPEHAVDPERATLAKAASENFPVAPFFLPRDWRTD
                     LMAVYGFARLVDDIGDGDLAPGGADARLLGVPGDRADDRLLMLDAFEADLHRVFDGIPR
                     HPLLRRLQPTVRRRSLTPEPFLGLIAANRQDQVVRRYETYDDLLAYCELSANPVGRLVL
                     AVTGTSTPERVRRSDAICTALQIVEHLQDVAEDLGRDRVYLPAEDMERFHVQETDLAAP
                     TAGAAVRALIAYETRRARDLLSEGAPLVGSVRGRLRLLLAGFVAGGRAAVRAIEAADHD
                     VLPGPPKPGKVQLLREVGVTLRGEG"
     gene            10918..11868
                     /gene="hpnD"
                     /locus_tag="SAM23877_RS30425"
                     /old_locus_tag="SAM23877_6411"
     CDS             10918..11868
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972236.1"
                     /locus_tag="SAM23877_RS30425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6411"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_053139967.1"
                     /sec_met_domain="phytoene_synt (E-value: 1.8e-55, bitscore:
                     186.8, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.8e-69,
                     bitscore: 231.6, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGTVESSAHTSAPVLAAYSYCEAVTGQQARNFAYGIRLLPTPKR
                     RAMSALYAFSRRVDDIGDGELAGDVKVARLEETRALLARIQDGAVDEDDTDPVAVALAH
                     AARAFPIPLGGLDELIDGVQMDLRGETYETWDDLKVYCRCVAGAIGRLSLGVFGAEPGA
                     RGAERAPEYADTLGLALQLTNILRDVREDAEDGRTYLPADDLAKFGCSAGFGGPTPPAG
                     SDFAGLVHFEVRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLR
                     GRVSLPGREKAYVAVRGLSGLDARHVTRRAVRKRA"
     gene            11868..12026
                     /locus_tag="SAM23877_RS41465"
     CDS             11868..12026
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039420.3"
                     /locus_tag="SAM23877_RS41465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6380 family protein"
                     /protein_id="WP_079030527.1"
                     /transl_table=11
                     /translation="MDVPGTLDTPDRSGASGEERRATLRWRSASLTETVGRTPFTHCGD
                     RTGKGAP"
     gene            12023..13459
                     /gene="hpnE"
                     /locus_tag="SAM23877_RS30430"
                     /old_locus_tag="SAM23877_6412"
     CDS             12023..13459
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330381.1"
                     /locus_tag="SAM23877_RS30430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6412"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_053139970.1"
                     /sec_met_domain="DAO (E-value: 7.1e-08, bitscore: 31.1,
                     seeds: 521, tool: rule-based-clusters)"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.2e-06, bitscore:
                     26.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHGNGTRDGGQLADVSALRPGGHAVVVGGGIAGVTAALTLADAG
                     VRVTLLEGRPRLGGLAFSFQRGDLTVDNGQHVYLRCCTAYRWFLDRIGGTALAPVQERL
                     DVPVVDLARPAGRRLGRLRRDALPVPLHLGRSLATYPHLSLAERAAVGRAALALKGLDL
                     TDPALDTQDFGSWLAAHGQSARAVEALWDLVGVATLNAVAGDASLGLAAMVFKTGLLSD
                     PGAADIGWARVPLGDLHDRMAREALDAAGVRTEVRTRVTSVRAKENGGWSVEVQGETLE
                     ADAVVLAVPQRETHDLLPAGALDAPANLLEIGTAPILNIHVVYDRKVLAAPFLAALGTP
                     VQWVFDRTEASGLKEGQYLALSQSAAQNEIDEPVAVLRERYLPELERLLPGTRGAGVKD
                     FFVTRERTATFAPDPGVGRLRPGARTKAPGLYLAGAWTATGWPATMESAVRSGVGAAGA
                     ALGALGRSRGLLPDFFGEAA"
     gene            13528..14586
                     /locus_tag="SAM23877_RS30435"
                     /old_locus_tag="SAM23877_6413"
     CDS             13528..14586
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972234.1"
                     /locus_tag="SAM23877_RS30435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6413"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_162492165.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.1e-57, bitscore:
                     192.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPAPKAAEAVDVTALLERGRTLTTPVLRAAVDRLAPPMDTVAAY
                     HFGWIDAQGRPADGDGGKAVRPALAVLSAEVTGAAPETGVPGAVAVELVHNFSLLHDDL
                     MDGDEQRRHRDTVWKVHGPAQAILVGDALFALANEVLLELGTVEAGRATRRLTKASRAL
                     IDGQAQDISYEHRDRVSVEECLEMEGNKTGALLASASSIGAVLGGADEHTADTLERYGY
                     HLGLAFQAVDDLLGIWGDPEATGKQTWSDLRQRKKSLPVVAALAAGGPASERLGEILAA
                     DAKTSDFANFSEEEFAARAALIEEAGGREWTADEARRQHTIAIEALDAVDMPERVRDRF
                     TALADFVVVRKR"
     misc_feature    complement(14681..14693)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            14706..16772
                     /gene="shc"
                     /locus_tag="SAM23877_RS30440"
                     /old_locus_tag="SAM23877_6414"
     CDS             14706..16772
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389111.1"
                     /locus_tag="SAM23877_RS30440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6414"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_053139974.1"
                     /sec_met_domain="T2TS (E-value: 8.7e-152, bitscore: 505.2,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGATLKPLAAAASETDDITIPPAAAGVPEAAARATRR
                     ATDFLLSLQDAQGWWKGDLETNVTMDAEDLLLRQFLGILDEETARAAALFVRGEQREDG
                     TWATFYDGPGDLSATIEAYVALRLAGDAPDTPHMAKAAEWIRSRGGIAAARVFTRIWLA
                     LFGWWKWDDLPELPPELIYFPTWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALD
                     ELHTDPAVPNPPRPLAPAASWDGAFQRLDRALHAYRRVAPRRLRRAAMNTAARWIIERQ
                     ENDGCWGGIQPPAVYSVIALYLLGYDLEHPVMRAGLESLDRFAVWREDGARMIEACQSP
                     VWDTCLAVIALADAGVPADHPQLVKAADWMLGEQIVRPGDWSVKRPGLPPGGWAFEFHN
                     DNYPDIDDTAEVVLALRRVRHHDPERVERAIGRGVRWNLGMQSKNGAWGAFDVDNTSAF
                     PNRLPFCDFGEVIDPPSADVTAHVVEMLAVEGLTHDPRTRRGIQWLLAEQEADGSWFGR
                     WGVNYVYGTGSVVPALTAAGLPASHPAVRRAVTWLESVQNDDGGWGEDLRSYRYVREWS
                     GRGASTASQTAWALMALLAAGERESKAVERGIAWLAATQREDGSWDEPYFTGTGFPWDF
                     SINYHLYRQVFPLTALGRYVHGDPFAEKHGVGNAAARAEQPAAQTSPAEVKGS"
     gene            16772..17416
                     /locus_tag="SAM23877_RS30445"
                     /old_locus_tag="SAM23877_6415"
     CDS             16772..17416
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016431357.1"
                     /locus_tag="SAM23877_RS30445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6415"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_053139976.1"
                     /transl_table=11
                     /translation="MNAQTGPSPLLIACALGIEHLALRTGDRGGAGGPVTVLRTGMGPR
                     AAERSVTRALAEDPTLGDAVVLATGFCAGLAPGMHPGDLVVAEETRDPRSTVACVGTDR
                     LVKELARALPRRTVHTGPLTGSDHVVRGPERADLLATGAIAVDMESAATLLSAVRAGAR
                     PVAAVRVVVDAPEHELVRIGTVRGGISAFRVLRSVLPAFFEWHRSLLLPRR"
     gene            17423..18445
                     /gene="hpnH"
                     /locus_tag="SAM23877_RS30450"
                     /old_locus_tag="SAM23877_6416"
     CDS             17423..18445
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386169.1"
                     /locus_tag="SAM23877_RS30450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6416"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_053139978.1"
                     /sec_met_domain="PF04055 (E-value: 7.1e-18, bitscore: 64.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 6.3e-09, bitscore: 34.3,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSVKVATYLAEQKIRRRDKFPLIVELEPLFACNLKCEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKRKYVF
                     LCTNALLMRKKMDKFKPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAIKEAKRRGF
                     RVTTNSTFFNTDTPQTIVEVLDYLNDDLKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFSGGNRARWRLNHSPLFLDFLEGKVDFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELVEETDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRALRETVSSNRE
                     "
     gene            18450..19604
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="SAM23877_RS30455"
                     /old_locus_tag="SAM23877_6417"
     CDS             18450..19604
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0044237 - cellular metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011031167.1"
                     /locus_tag="SAM23877_RS30455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6417"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_053139980.1"
                     /transl_table=11
                     /translation="MTAIPLGVPEVPVRPLAERRVSRRIQVGPVAVGGGAPVSVQSMTT
                     TRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALPVIAKKSQIPVIADIHFQPKYV
                     FAAIEAGCAAVRVNPGNIKQFDDKVKEIAKAAKDHGTPIRIGVNAGSLDRRLLQKYGKA
                     TPEALAESALWEASLFEEHDFRDIKISVKHNDPVVMVEAYRQLAAQCDYPLHLGVTEAG
                     PAFQGTIKSAVAFGALLSQGIGDTIRVSLSAPPVEEIKVGIQILESLNLRQRGLEIVSC
                     PSCGRAQVDVYKLAEEVTAGLEGMEVPLRVAVMGCVVNGPGEAREADLGVASGNGKGQI
                     FVKGEVIKTVPESKIVETLIEEAMKIAEQLEKDGASGEPAVTVS"
     gene            19632..21572
                     /gene="dxs"
                     /locus_tag="SAM23877_RS30460"
                     /old_locus_tag="SAM23877_6418"
     CDS             19632..21572
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972229.1"
                     /locus_tag="SAM23877_RS30460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6418"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_053139982.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 2.4e-110,
                     bitscore: 366.8, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.9e-06, bitscore:
                     25.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMLENIRGPRDLKALSETELGELTREIRDFLVHAVARTGGHLGP
                     NLGVVELTVALHRVFESPADRILWDTGHQTYVHKLLTGRQDFSKLRGKGGLSGYPSREE
                     SEHDVIENSHASTVLGWADGLAKAHQVLGREDHVVAVIGDGALTGGMAWEALNNIAAAR
                     DRPLIIVVNDNERSYAPTIGGLANHLATLRTTDGYERVLAWGKDVLQRTPVVGNTVYEA
                     LHGAKKGFKDAFAPQGLFEDLGLKYLGPIDGHDIEAVESALRRAKRFHGPVLVHCLTEK
                     GRGYEPALRDEEDHFHTVGAMDPLTCAPLTPPPGPSWTSVFGEEMVRIGEERDDVVAIT
                     AAMLHPVGLAAFAERFPDRVWDVGIAEQHAAVSAAGLATGGLHPVVAVYATFLNRAFDQ
                     LLMDVALHRCGVTFVLDRAGVTGVDGASHNGVWDMSVLQVVPGLRIAAPRDADQLRAQL
                     REAVAVDDAPTLVRFPKESVGPAVPAVGRAGSMDVLRAPDRPEVLLVSVGVMAPVCLRA
                     AELLEARGIGCTVVDPRWVKPVDPALAPLAARHRLVAVVEDNSRAAGVGSAVALALGDA
                     DVDVPVRRFGVPEQFLAHAKRAEVLADIGLTPVDIASRISAGLAVAAETGERAEGPTGD
                     GRTVTPAQGEN"
     gene            21573..22958
                     /locus_tag="SAM23877_RS30465"
                     /old_locus_tag="SAM23877_6419"
     CDS             21573..22958
                     /NRPS_PKS="Domain: Aminotran_3 (41-363). E-value: 7.4e-91.
                     Score: 296.6. Matches aSDomain:
                     nrpspksdomains_SAM23877_RS30465_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389116.1"
                     /locus_tag="SAM23877_RS30465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6419"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_053139984.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.6e-88, bitscore:
                     295.8, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKEFDLAALLAERGAERYELHAKHLNHQLPRMLHTIGFDKVYER
                     AEGAHFWDADGNDYLDMLAGFAVMGLGRHHPVVRKALHDVLDASLADLTRFDCPPLPGL
                     LAERLLSYSPHLDRVFFGNSGTEAVETALKFARYATGRPRVLYCSHAFHGLTTGSLSVN
                     GESGFRDGFAPLLPDTAVPLGDLDALARELRRGDVAALIVEPIQGKGVHEAPPGYLRAA
                     QDLLHRHKALLIADEVQTGLGRTGTFYAFQHEDGVEPDLVCVAKALSGGYVPVGATLGR
                     DWIFQKVYSSMDRVQVHSASFGSNAQAMAAGLAVLSVMENEEIVANAAAVGERLKSRLA
                     ELVDRYEMLADVRGRGLMIGIEFGRPRSLKLRSRWTMLQAARKGLFAQMVVVPLLQRHR
                     ILTQVSGDHLEVIKLIPPLIIDTADADRFVDAFTEVMEDAHHGGGLMWDFGKTLVRQAV
                     ANR"
     aSDomain        21696..22661
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAM23877_RS30465_Aminotran_3.1"
                     /evalue="7.40E-91"
                     /label="SAM23877_RS30465_Aminotran_3.1"
                     /locus_tag="SAM23877_RS30465"
                     /protein_end="363"
                     /protein_start="41"
                     /score="296.6"
                     /tool="antismash"
                     /translation="VYERAEGAHFWDADGNDYLDMLAGFAVMGLGRHHPVVRKALHDVL
                     DASLADLTRFDCPPLPGLLAERLLSYSPHLDRVFFGNSGTEAVETALKFARYATGRPRV
                     LYCSHAFHGLTTGSLSVNGESGFRDGFAPLLPDTAVPLGDLDALARELRRGDVAALIVE
                     PIQGKGVHEAPPGYLRAAQDLLHRHKALLIADEVQTGLGRTGTFYAFQHEDGVEPDLVC
                     VAKALSGGYVPVGATLGRDWIFQKVYSSMDRVQVHSASFGSNAQAMAAGLAVLSVMENE
                     EIVANAAAVGERLKSRLAELVDRYEMLADVRGRGLMIGIEF"
     gene            23025..23663
                     /locus_tag="SAM23877_RS30470"
                     /old_locus_tag="SAM23877_6420"
     CDS             23025..23663
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972227.1"
                     /locus_tag="SAM23877_RS30470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6420"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_053139986.1"
                     /transl_table=11
                     /translation="MSSSETTDPAEGSVAAVAPQLRELRRRAALTLEAAARAAGLSPAH
                     LSRLETGQRQPSLPMLLSLARVYGTTVSELLGETAADRDAVVRAEAMEPTSAGGWTYWQ
                     AGGSGRGMQALRVRVPHGSQGDIVRVHPGEEWLHVLRGRLRLRLGDTVHRLGPGDSAHF
                     DSLTPHRIAAQDADGVELLFVHTLLQSPTAALCLGPATVPPHSTPGEMP"
     gene            23660..23782
                     /locus_tag="SAM23877_RS30475"
                     /old_locus_tag="SAM23877_6421"
     CDS             23660..23782
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330475.1"
                     /locus_tag="SAM23877_RS30475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6421"
                     /product="DUF6126 family protein"
                     /protein_id="WP_053139988.1"
                     /transl_table=11
                     /translation="MNLQDKFPRALWVRLFIYLVVGHAFAAFIYLLFEVGAGSR"
     gene            complement(23793..24590)
                     /locus_tag="SAM23877_RS30480"
                     /old_locus_tag="SAM23877_6422"
     CDS             complement(23793..24590)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019069689.1"
                     /locus_tag="SAM23877_RS30480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6422"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_053139990.1"
                     /transl_table=11
                     /translation="MTQQVPSTEPELAGVRNFRDVGGLPTVDGRRVRQGVLFRSGHLAH
                     ATGGDAAFLASLGLHTIFDFRNAADQKLEGPDVELPGVRNVNLPLSDPADGAEFWKMVR
                     DGDLDQLREILAGDKGAERMIGSYRLIIKERTAEHSRVLHALAEDSVPALMHCAAGKDR
                     AGLSIAITLLALGVERDAIVEDYLKSNATHRRYKVRRSSTAASAYSPEVMELLSPLFDA
                     RAEYLAAAFETVEQTWGGVDAYLEQGLGITPQTRERLRERMLD"
     misc_feature    24692..24707
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.38"
                     /tool="antismash"
     misc_feature    24802..24816
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.85"
                     /tool="antismash"
     misc_feature    24809..24823
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.23"
                     /tool="antismash"
     misc_feature    complement(24980..24994)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 20.54"
                     /tool="antismash"
     regulatory      25015..25172
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            25177..26133
                     /locus_tag="SAM23877_RS30485"
                     /old_locus_tag="SAM23877_6423"
     CDS             25177..26133
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972224.1"
                     /locus_tag="SAM23877_RS30485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_6423"
                     /product="LysM peptidoglycan-binding domain-containing M23
                     family metallopeptidase"
                     /protein_id="WP_053139992.1"
                     /transl_table=11
                     /translation="MPAKGKHRRTRAMRLTRTIAVAGTGGAALALPLMGAAGAHAAPAQ
                     SVSEHSVQSVATSAKKAAGAEKNGDSRTYTVKSGDYLSKIADEQDVDGGWKKLYADNRE
                     VVGSDPSLIHPGLKLAVAGQAAKSSAPSSSAASEKPAAEKPAAAEKPAPAKAESAEQSS
                     DAAKSSADSSNTSAQSAGTGSGFASPVPSGTLGTPYHQTGSMWSSGYHTGTDFVVPTGT
                     SLKAVGAGTVVSAGWGGAYGNQVVIQLADGHYAQYAHLSSLSVSAGQSVTAGQQVGLSG
                     ATGNVTGPHLHFEIRTTPDYGSDVDPVAYLRSHGVSL"
     misc_feature    complement(26290..26300)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 16.96"
                     /tool="antismash"
     misc_feature    complement(26339..26351)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     misc_feature    complement(26378..26390)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     misc_feature    26459..26478
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.46"
                     /tool="antismash"
ORIGIN
        1 cgccggtgct cgccgtggag gtcgccgtgg ggcccgagtg ggtccgggtg tccgtggagg
       61 acaaccaccc ctaccgcccg accgccctgg agaccgatca cggccggacg ggcgggcgcg
      121 ggctgctcct ggtccgggag atcacccggg aggcgggcgg agcgtgcgac gtcgcccaca
      181 cggcgggcgg cggcaaggtg atctgggtcg ccctgccgct cgaacacgcc ctgcgctagg
      241 ccgggctcac cagccggccg acgggcccgt cagctcgcgg acggcgggcc gggccgcgtc
      301 cagcaccgtc atgaaccacg cggagaaggt gtccttcccg tgccgctcga tcagctcggc
      361 cggagacacc agggccgtct cggccacctc ctccgggtcg ggccgcggcg gcgcctgcac
      421 cagacccacg aagagatggt tgtactcctg ctccaccagc cccgaggccg ggtccgggtg
      481 gttgtagcgc accgtgccgg cctcggcgag cagcgacggc gagaccccca gctcctcgta
      541 cgtccgccgg gccgccgccg cgaagggcgc ctcaccggga tagggatggc cgcagcaggt
      601 gttggaccac acaccggggg agtggtactt gccgagcgct cgctgctgga tcagcaaccg
      661 cccccgctcg tcgaacagga acacggagaa cgcgcggtgc agtcgtccgg gcggctggtg
      721 cgcggagagc ttctccgcgg tgccgatcgt cacgccgtcc tcgtcgacca gttccagcaa
      781 aatcgcgtcc gcggtgccgt tcgacgcatc gtgcgtcgcg gtggcaggag tgatcggcat
      841 acccatcctt cacatcggtc ctcgcgcccc aagtgtgccg tacgaatccg gcactctcgg
      901 cacttcccgg cactccgcat gtcccgcgcc gcggcgcggg cggcggtcgt gaccggtcgg
      961 acgccgaggt ggggcccggg ggttgatcgt tcccggaggg cgggccggga acccccgggg
     1021 gcgtcaccgg ctccagtgcc cgggagacag ggagcggacg accggcggac ggctgcgccg
     1081 cccggcgcgt tccctcgcgc acgcgccccc tgcggtggcc ggccgggggc gcggctcagt
     1141 ggcacaaccg cgcctcgtgc tccgcgtggc cgctgggctc cagctggaag gtgcagtgct
     1201 ccacgtcgaa gtggtcgccg aggcagccct gcaactcgtg gagcatcttc tcgtggccga
     1261 tcgcgctcag cgcctcgccg ctcaccacca cgtgcgccga gagcaccggc atgcccgagg
     1321 tgatcgtcca ggcatgcagg tcgtggacgt cctcgacccc gtccagcgcc agtatgtggg
     1381 cgcgcacctc ggcgatgtcc acgcccttgg gcgcggcctc cagcagcacg tccagggtct
     1441 cgcggagcag ccgcagggtg cgtggcacga tcatcaggcc gatgagcagc gacgcgatcg
     1501 ggtccgccgc ctgccagccg gtggccagga tcaccagcgc cgagacgatc acggtcagcg
     1561 atcccagcgc gtcggccgcc acctccagga aggcgccccg cacgttcagg ctctccttct
     1621 gcccgcgcat cagcagcgtc agcgacacca tgttggcgac caggccgatc acaccgaaca
     1681 cgacggtcag accgccctcg gtgtcggcgg gtgtgaggaa gcgctcgacc gcttcgaaca
     1741 gcacgtagcc gccgacgccg agcagcagca cacagttggc cagggccgcg aggatctccg
     1801 cccgggcgaa gccgaaggtg cgccggtcgc tcggcgggcg gttcgcgaag tggacggcga
     1861 gcagcgccat gccgagcccc agggcgtcgg tcgccatgtg ggccgcgtcg gcgaccaggg
     1921 cgagcgagtc cgcgagcatg ccgccgacga tctggaccac catgacgaag agcgtgatcg
     1981 ccagtgccac ccggagcctg ccgaggtacg cggcggtcgc cgtgcccccg gcgcgcgccc
     2041 cgtgcgcatg cccgtgatcg tgcccagccc ccatgagaag cccgcctccc tgtgtcttcg
     2101 gcatccggtg tccggatcac agtcaactac gggcgggggg tatcgggcaa cgcggcactg
     2161 aacaccgttg tcatgtgccc tgacctgcgg aaacggtgtg caggtcaggg cactgcgagg
     2221 ctccgtgagg gccgtccggg tgacggctcg ccgccgtcgc cccgctccgt tgcgatgacc
     2281 ctctgtggcc accctcggac gcttcgcgat gtccgcgatg cccggtctgg gggcgcggtt
     2341 tgtggggcgg ggcccgcatc cacgatgatg atcgcggcaa aggcgggtgc acgtggtgcc
     2401 gaccgaccgt gaaacgggcg gtgaacacgg cgttcggggc atccgataac ctctgccgac
     2461 atgccgcccg ggtgccgcag gcgcgggcgt cccaccatgt acaggaccgg cgccccgggc
     2521 gtcggcacca gggagtgagt tcggttgccg accgccatcc tcaccggtca gccggtcccc
     2581 ggttcgtcga tcgagagcga gctgcggtcc ctgggcttcg aggtgcgtgc cgcctccggt
     2641 gcggccgacg ccgagctgct gctcgcccag gtctccgccg gggaacgggt cgccctggtc
     2701 gacgcccgct tcgtgggcca cctgcactcc ctgcgcctcg gtctcaccga cccccgcttc
     2761 ccgctcgccg cgatcccggg cgctgtgacc gcacagccgg cggcccgcca ggccctgacc
     2821 cgtgcgatgg cccgcgagaa cctcgcggtc ggcggtgccg cgctcggggg cgctcccgct
     2881 cgggtgcggc agggcgaagg ggacgccgag agcctcgccg accggatcac cgccgccctc
     2941 gacgccgacg gcgccgacgt gcaccggccc gagctcggca gcctcgtcgc cgccgtcccc
     3001 gcggacccgc aggcccgcaa cgaggcacgg cagtccgtcg ccgccgtcga cgacgaggcc
     3061 gtacgtctga agtcggcggt gaaggcccgc gacgggttcg tcaccacctt cttcatcagc
     3121 ccctactccc gctacatcgc ccgctggtgc gcgcgacgcg gactgacccc caaccaggtc
     3181 accaccgcct cgctgatcac cgcgctcata gccgcgggtt gcgcggccac cggcacccgc
     3241 ggcggcttcg tcgccgccgg cgtcctgctc atcgcctcct tcgtcctcga ctgcaccgac
     3301 ggacagctgg cccgctactc cctgcagtac tcgacgctcg gcgcctggct ggacgccacc
     3361 ttcgaccgcg ccaaggagta cgcctactac gcgggcctcg ccctgggagc cgcccgtggc
     3421 ggcgacgacg tgtgggccct ggccctcggc gcgatggtcc tccagacctg ccggcacgtc
     3481 gtcgacttct cgttcaacga ggcgaacgtc gacagtacgg ccgccgccgc caacaccagc
     3541 cccaccgccg ccctctccga caagctcgac agcgtcggct ggacggtctg ggcgcgccgc
     3601 atgatcgtcc tgcccatcgg cgaacgctgg gccatgatcg ccgtactgac cgcggtcacc
     3661 accccgcgca tcaccctcta cgcgctgctc gtcggctgcg ccttcgccgc gacgtacacc
     3721 accgccggcc gggtcctgcg ctcgcagacc cggaaggcgt cgcgcaccga ccgggccgcg
     3781 aaggcgctgg ccgacctcgc cgactccgga ccgctcgccg aggccgtcgc cgcgggcctg
     3841 cgcaagcccg cccgccggct gcccggcttc accgcccccg ccgtcgccct cctcggcggc
     3901 ctcgccgtcg tcgccacggc ggcgctcacc ggcttcggcg gcccctggcc ggtcgtcgcc
     3961 gccgtcgcct acgtcctgac ctccggcctc gccgtcgccc gccccctcaa gggcgccctc
     4021 gactggctgg tccccccctt cctgcgcgcc gccgagtacg gcaccgtcct ggtactggcg
     4081 gcgaaagcag acgtgaacgg ggcccttccg gcggctttcg gcctggttgc ggcggtcgcc
     4141 taccatcact acgacacggt ctaccgcatc cgcggtggcg cgggcgcgcc gccgcagtgg
     4201 ctggtgcgga cgatcggggg gcacgagggc cgcacgctgg tgatcaccgt gctggccgtg
     4261 ctgctcaccg ccacacagtt caagctcgcg ctcacggtcc tcgccgtggc cgtggcactc
     4321 gtggtgctcg tcgagagcat ccgcttctgg gtcgccgccc accagggcgg cgcacccgcc
     4381 gtacacgacg aaggagaacc cgcatgatcg gcctcgtgct ggccgccggc gccggccggc
     4441 gtctgcgccc ctacaccgac accctgccga aggcactggt gccggtcggc cccgaggggg
     4501 cggaggacag catcacggtg ctggacctga ccctggcgaa cttcgccgag gtcggcctga
     4561 ccgaggtcgg gatcatcgtc ggctaccgca aggaagccgt gtacgaccgc aaggaggcgc
     4621 tggagcagaa gtacggcgtc aagctcaccc tcatcgacaa cgacaaggcc gaggagtgga
     4681 acaacgccta ctccctgtgg tgtggtcgtg acgccctcaa ggacggcgtg atcctcgcca
     4741 acggcgacac cgtgcacccg gtctccgtcg agaagaccct gctcgccgcc cgcggcgacg
     4801 gcaagaagat catcctcgcc ctcgacacgg tgaagagcct cgccgaggag gagatgaagg
     4861 tcgtcgtcga ccccgacaag ggcgtccagc gcatcaccaa gctgatggac ccgtccgagg
     4921 cgaccggcga gtacatcggc gtcaccctca tcgagggcga ggccgccgtg gagctggccg
     4981 acgccctgaa gacgaccttc gagcgcgacc cgcagctgta ctacgaggac ggctaccagg
     5041 agctcgtcaa ccgcggcttc aaggtcgacg tggcgccgat cggcgaggtc aagtgggtcg
     5101 agatcgacaa ccacgacgac ctcgccaagg gcagggagat cgcgtgccag tactgacgag
     5161 gctcatcccg tcgccggtcg tcgtggacat ccgcgcgggt gccctcgacg acctgggatg
     5221 tgtgctcgcc gacgagcgca tctcccactc gggcaagctc gccgtcgccg tcagcggcgg
     5281 ctcgggcgcc cggctgcgcg agcgcgtcgc cccgtccctg cccggcgccg actggttcga
     5341 ggtcggcggc ggcaccctgg acgacgcgat caagctggcc ggcgccatga aggccggtca
     5401 ctacgacgcg gtcgtcgggc tcggcggcgg caagatcatc gactgcgcca agttcgccgc
     5461 cgcccgtatc ggcctcccgc tggtcgccgt gccgacgaac ctcgcgcacg acggactgtg
     5521 ctcgccggtc gcgaccctcg acaacgacgc gggccgcggc tcctacggcg tcccgaaccc
     5581 gatcgccgtc gtgatcgacc tggacgtcat ccgcgaggcc ccggtgcggt tcgtgcgcgc
     5641 cggtatcggc gacgcggtct ccaacatctc cgcgatcgcg gactgggagc tggccaaccg
     5701 ggtcaagggc gagcgcatcg acggcctggc cgccgcgatg gcccgccagg cgggcgaggc
     5761 cgtcctgagg cacccgggcg gcgtcggcga caacgacttc ctccaggtgc tcgccgaggg
     5821 cctggtcctg accggcatcg ccatgtcggt ctccggtgac tcgcggcccg cctccggcgc
     5881 ctgccacgag atcaaccacg ccttcgacct gctcttcccc cagcgcacgg ccgcccacgg
     5941 tgagcagtgc ggcctgggcg cggccttcgc gatgtacctg cgcggggccc acgaggagtc
     6001 cgcccacatg gccgaggtgc tgcgccggca cgggctgccg gtgctgccgg aggagatcgg
     6061 gttcaccccg gaggagttct tccgggccgt ggagttcgcc ccgcagacgc ggcccggccg
     6121 ctacacgatc ctcgagcacc tcgacctcaa aaccgaccag atcaaggacc tgtacgccga
     6181 ctatgtcaag gccatcggta gctgaactac gtccggtcgt ccatcccgcg ggggtcaagg
     6241 accggcgcag cggtgagcac tgggcgggac gcctctacat gcgcgaggtc tcgctgcgga
     6301 tcgaccgcta cctggtgaac accagggtca cgcccaacca gctcacgtac ctgatgaccg
     6361 tctgcggcgt cctcgcggcc ccggcgctgc tggtgccggg catcacgggc gccgtgctcg
     6421 gcgtcgtggc ggtccagctc tacctgctgc tggactgcgt cgacggcgag gtcgcgcgct
     6481 ggaagaagca gtactcgctc ggcggcgtct acctggaccg ggtcggcgcc tacctgaccg
     6541 acgccgcggt cctggtcggc ctcggcctgc gcgccgccga cctctggggc accggccgga
     6601 tcgactggct gtgggccttc ctcggcaccc tggccgccct cggcgccatc ctgatcaagg
     6661 ccgagaccga cctggtgggc gtggcccggc accagaccgg gagggcaccg gtccaggagt
     6721 ccgcgtccga gccgcgctcc tccggcatgg cgctggcccg ccgggccgcc ggggcgctca
     6781 agttccaccg gctgatcctc ggcatcgagg cgtcgctgct gatcctggtc ctcgcgatcg
     6841 tcgacgagag ccgcggcgac ctgttcttca cccgcctcgg tacggccgta ctggccggca
     6901 tcgcgctgct gcagaccctc ctgcacctgg tgtccatcct cgcctccagc aggctgaagt
     6961 gagcgggtcc atgaaggtcg gcgccgtcgt catcacgatg ggcaaccgcc ccgacgagct
     7021 gcgggccctg ctcgactcgg tcgcccggca ggacggcgac cgcgtcgagg tggtcgtcgt
     7081 cggcaacggc tcgcccgtcc cggaggtgcc ggagggcgtg cgcaccgtcg agctgcccga
     7141 gaacctgggc atccccggcg gccgcaacgt cggcatcgag gccttcggtc cgggcggcag
     7201 cgacgtcgac atcctgctct tcctcgacga cgacggcctg ctcgcccgca ccgacaccgc
     7261 ggagctgtgc cgccaggcct tcgcggccga cgacgagctc ggcatcatca gcttccgcat
     7321 cgccgacccg gacaccggcg agacccagcg ccggcacgtc ccgaggctgc gcgcctccga
     7381 cccgatgcgc tcctcccggg tcaccacctt cctcggcggt gccaacgcgg tgcgtacccg
     7441 cgtcctcacg caggtcggcg gcctgccgga cgcgttcttc tacgcccacg aggagaccga
     7501 cctggcgtgg cgggccctcg acgccggctg gatgatcgac taccggtcgg acatggtgct
     7561 gaaccacccc acgaccgcgc cgtcacggca cgcggtctac caccgcatgg tcgcccgcaa
     7621 ccgcgtctgg ctcgcccgcc ggaaccttcc cgcgctcctc gtcccggtct acctcggcgt
     7681 gtggatgctg ctcaccctgc tgcgccggcc ctcgcgacct gccctcaagg cctggttcgg
     7741 cggcttccgc gagggctggg ccaccccctg cggcccccgg cggcccatga ggtggcgtac
     7801 ggtgtggcgg ctgacccggc tgggccggcc tcccgtgatc tgacaagctc gtacccgaga
     7861 gcgtcccggc ccgcccgggg ccaacaggtc catgccaggc ccgcgcggcc gagcactccg
     7921 aagacgaaag tttccaccag tgagtgagac aacgcacgac ggcacggtcg ccatgaccaa
     7981 gcccgtgtcg cccgacgagg gcctcacacc ggccaggctc gccgccaagt acgggctgtc
     8041 ggtgagcggg gcccggccgt ccctcgcgga gtacgtccgt cagctctgga gccggcggca
     8101 cttcatcctc gccttctccc aggcgaagct gaccgcccag tacagccagg ccaagctcgg
     8161 ccagctgtgg caggtggcca cgcccctgct caacgcgctc gtctacttca cgatcttcgg
     8221 cctgatcctg aacgccggca agggcatgcc gaaggacgtg tacatcccgt tcctggtgac
     8281 gggtgtgttc gtcttcacct tcacccagtc ctcggcgatg gcgggcgtgc gcgcgatctc
     8341 cggcaacctc ggcctggtgc gggcgctgca cttcccgcgc gcctcgctcc cgatctcgtt
     8401 cgccctccag cagctccagc agctcctggc ctcgatgatc gtcatgttcg cggtggtgat
     8461 cggcttcggc agctatccct ccctgtcctg gctcctggtc gtcccggcgc tgctcctgca
     8521 gttcctcttc aacatgggcc tggcgctgat cgtggcccgg atgggcgcca agacgccgga
     8581 cctggcccag ctgatgccct tcatcatgcg gacgtggatg tacgcgtcgg gcgtcatgtt
     8641 ctccatcccg atcatgctgg aggacaagcc gacctggctg gcggacgtcc tccagtggaa
     8701 cccggccgcc gtctacatgg acctgatccg cttcgcgctg atcgacgggt acggctcgga
     8761 gaacctgccg ccgcacgtgt gggcggtcgc gctcggctgg gccgtggtcc tggccgtggg
     8821 cggcttcgtg tacttctgga aggcggagga gaggtacggc cgtggctgag cagcagcagg
     8881 gcgagcgggt gccgacggtc atcgcggacg aactgcacat cgtctaccgg gtcaacggcg
     8941 ccaggaccgg caagggcagc gcgaccgcgg ccctcagccg catgatcaaa cggggcgagg
     9001 acaggggcgt gcgcaaggtg cacgccgtgc ggggcgtgtc gttcaccgcc taccggggcg
     9061 aggcgatcgg cctgatcggt tccaacggat ccggcaagtc gaccctgctg cgggccatcg
     9121 ccggcctgct gcccgccgag cgcggcaagg tctacacgga cggccagccc tccctcctgg
     9181 gcgtgaacgc ggccctgatg aacgacctga ccggcgagcg caacgtcatc ctcggcggtc
     9241 tggccatggg catgtcccgc gagcagatca aggagcgcta ccaggacatc gtcgacttct
     9301 ccggcatcaa cgagaagggc gacttcatca ccctgccgat gcgcacgtac tcctccggca
     9361 tggcggcccg gctgcgcttc tccatcgccg ccgccaagga ccacgacgtc ctgatgatcg
     9421 acgaggccct cgccaccggc gaccggaagt tccagacccg ctccgaggag cgcatccggg
     9481 agctgaagaa ggaagccggc accgtcttcc tggtcagcca caacaacaag tccatccgcg
     9541 acacctgcaa ccgcgtcctg tggctggaac gcggcgagct gcggatggac ggcccgacgg
     9601 acgaggtgct caaggagtac gagaagttca cgggcaagta gggcgacgcg ccgaaggccc
     9661 cgccggagct gttccggcgg ggcacgcgtc tgcaaaggaa gcgtcaactc cggctgttct
     9721 caggaatctt gaggccgatc gatgtgttct tgtgatgcgc ggagcacccc tgcggacctc
     9781 ggtgagttgt acaacgtaag ctggagcggt cccgatacgc ggcacatggg gcgataatcc
     9841 ccgacaccct cgagcgggcc cgccgcgcgg gcggtcgggc ggcgtgtccg aaatagtgtg
     9901 tattgggtcg gcagtgtaga acgggagatg tgacggcaat ggcgacggaa actccccacc
     9961 tccgcgacgc gtgcgccgtc cccgcccagg gctgcccgcg atgacggcca ccgacacggc
    10021 gcgcgccgtg gacccggagc acgccgtgga cccggagcgc gccaccctcg ccaaggcggc
    10081 gagcgagaac ttccccgtgg cccccttctt cctcccccgc gactggcgca ccgacctcat
    10141 ggccgtctac ggcttcgccc gtctggtcga cgacatcggc gacggcgacc tggcccccgg
    10201 cggcgccgac gcccgcctcc tcggcgtccc cggcgaccgg gccgacgacc ggctgctgat
    10261 gctggacgcc ttcgaggccg acctgcacag ggtcttcgac ggcatccccc gccacccgct
    10321 gctgcgccgc ctccagccca ccgtgcgccg ccgctcgctg acccccgagc ccttcctcgg
    10381 cctgatcgcc gccaaccgcc aggaccaggt ggtgcggcgg tacgagacct acgacgacct
    10441 gctcgcctac tgcgagctgt ccgccaatcc ggtcggtcgc ctcgtcctcg ccgtcaccgg
    10501 cacctcgacg cccgagcggg tccgccggtc cgacgcgatc tgcaccgccc tgcagatcgt
    10561 cgagcacctc caggacgtcg ccgaggacct gggccgtgac cgcgtctacc tgcccgccga
    10621 ggacatggaa cgcttccacg tccaggagac ggacctcgcc gcgcccaccg ccggcgccgc
    10681 ggtgcgcgcc ctgatcgcgt acgagacccg acgcgcgcgc gacctgctga gcgagggcgc
    10741 ccccctggtg ggcagcgtcc gcggcaggct ccgcctgctg ctcgccgggt tcgtggcggg
    10801 gggcagggcg gccgtccggg cgatcgaggc cgccgatcac gacgtacttc ccggcccgcc
    10861 caagcccggc aaggtccagt tgctgcgcga ggtgggcgtg accctgcgag gagaggggtg
    10921 atcgggaccg tggagtcgtc agcgcacacg tcggcaccgg tgctcgccgc ctacagctac
    10981 tgcgaggccg tcaccggaca gcaggcccgc aacttcgcct acggcatccg gctcctgccg
    11041 acgcccaagc gccgggccat gtcggcgctg tacgcgttct cacgccgcgt cgacgacatc
    11101 ggcgacggag agctcgcggg tgacgtcaag gtcgcccggc tggaggagac gcgggcgctg
    11161 ctcgcccgga tccaggacgg ggcggtggac gaggacgaca ccgacccggt cgccgtcgcc
    11221 ctcgcccacg ccgcgcgcgc cttcccgatc ccgctcggcg ggctcgacga gctgatcgac
    11281 ggcgtccaga tggacctgcg gggcgagacc tacgagacct gggacgacct gaaggtctac
    11341 tgccgctgtg tggcgggcgc catcggccgc ctctcgctcg gcgtgttcgg cgccgaaccg
    11401 ggggcgcgcg gcgccgaacg cgcgcccgag tacgccgaca cgctcggcct cgcgctccag
    11461 ctcaccaaca tcctgcggga cgtccgcgag gacgccgagg acgggcggac ctacctgccc
    11521 gccgacgacc tcgccaagtt cggctgctcc gccggattcg gcggaccgac gccgcccgcg
    11581 ggctccgact tcgccggcct cgtccacttc gaggtgcgtc gggcccgcgc cctcttcgcc
    11641 gagggctacc ggctgctgcc catgctcgac cggcgcagcg gcgcctgcgt ggccgccatg
    11701 gccggcatct accgccgcct cctggaccgc atcgagcggg acccggaggc cgtcctgcgc
    11761 ggccgggtct cgctccccgg acgcgagaag gcgtacgtcg ccgtgcgcgg cctgtccggg
    11821 ctggacgccc ggcacgtcac ccggcgggcc gtcaggaagc gcgcctgatg gacgtacccg
    11881 gcacactcga cactccggac cggagcggcg cctccggcga ggaacggcgg gcaaccctcc
    11941 ggtggcggtc ggcgtccctg actgagacgg tcggccgtac accgttcaca cactgcggcg
    12001 accggacagg gaagggcgca ccatgacgca cggcaacggc acgcgggacg gcggacagct
    12061 cgcggacgtc tccgccctcc ggcccggcgg acacgccgtc gtggtcggtg gcggaatcgc
    12121 cggggtcacc gccgccctca cgctcgccga tgccggggtg cgcgtcaccc tgctcgaagg
    12181 acggccgcga ctgggcgggc tcgccttctc cttccagcgc ggcgacctca ccgtcgacaa
    12241 cggccagcac gtctacctgc gctgctgcac cgcctaccgc tggttcctcg accgcatcgg
    12301 gggaacggcc ctcgctccgg tgcaggaacg tctcgacgtg ccggtcgtcg acctggcccg
    12361 gcccgcggga cgacggctcg gcagactgcg gcgcgacgcg ctgccggtgc ccctgcacct
    12421 ggggcggagc ctcgccacgt acccgcacct ctcgctcgcc gagcgggccg cggtcgggcg
    12481 ggccgcgctc gcgctcaagg ggctcgatct caccgatccg gcgctggaca cccaggactt
    12541 cggcagctgg ctggccgcgc acggccagtc ggcgcgcgcc gtcgaggcgc tgtgggacct
    12601 cgtcggcgtc gcgaccctca acgcggtcgc gggcgacgcc tcgctggggc tcgccgcgat
    12661 ggtgttcaag accggtctgc tgtccgaccc gggcgcggcc gacatcgggt gggcccgggt
    12721 cccgctgggc gacctgcacg accggatggc ccgcgaggcg ctcgacgccg cgggcgtccg
    12781 caccgaggtc cgtacccgcg tcacctccgt ccgggcgaag gagaacggag gctggagcgt
    12841 cgaggtccag ggcgagaccc tggaggccga cgcggtcgtc ctggccgtgc cgcagcgcga
    12901 gacgcacgac ctgctgcccg cgggcgccct cgacgccccc gcgaacctgc tggagatcgg
    12961 cacggcgccg atcctgaaca tccacgtcgt ctacgaccgc aaggtgctcg ccgcgccgtt
    13021 cctcgcggct ctcggcaccc ccgtgcagtg ggtgttcgac cgtaccgagg cctccgggct
    13081 gaaggagggt cagtacctgg cgctgtcgca gtcggccgcg cagaacgaga tcgacgagcc
    13141 cgtggccgtg ctgcgcgagc ggtacctgcc cgagctggag cggctgctgc ccggcacccg
    13201 gggcgccggg gtgaaggact tcttcgtgac cagggagcgc accgcgacct tcgctcccga
    13261 ccccggcgtc ggccggctcc ggcccggcgc ccgcaccaag gcacccggcc tgtacctggc
    13321 cggagcgtgg accgccaccg ggtggcccgc gaccatggag agtgcggttc gcagcggtgt
    13381 cggggcggcg ggcgccgcgc tcggcgccct gggccggtcc cgcggcctgc ttcccgactt
    13441 cttcggggag gcggcatgag aaccgatccg cgtgggaccg actcccgcac tcccggtacc
    13501 gcaactggag gaaagactgt gcccactgtg cccccggccc cgaaggctgc cgaggcggtg
    13561 gacgtgaccg cgctcctgga gcgtggccgg accctgacca cgccggtcct gcgggctgcc
    13621 gtagaccgtc tggcacctcc catggacacc gtcgccgcct accacttcgg ctggatcgac
    13681 gcccagggca ggcccgcgga cggtgacggc ggcaaggccg tccgccccgc gctcgcggtg
    13741 ctctccgccg aggtcaccgg tgccgcgccc gagacgggcg tccccggcgc ggtggcggtg
    13801 gagctggtgc acaacttctc cctcctgcac gacgacctga tggacggcga cgagcagcgc
    13861 cgccaccgcg acaccgtctg gaaggtgcac ggccccgccc aggccatcct ggtcggcgac
    13921 gccctgttcg cactcgccaa cgaggtgctg ctggagctcg gcaccgtcga ggcgggccgt
    13981 gccacccgcc gcctcaccaa ggcctcccgc gccctgatcg acggtcaggc ccaggacatc
    14041 tcctacgagc accgcgaccg cgtcagtgtc gaggagtgcc tggagatgga gggcaacaag
    14101 accggcgccc tgctcgcctc cgccagctcc atcggcgcgg tgctcggcgg cgccgacgaa
    14161 cacaccgccg acacgctgga gaggtacggc taccacctgg gcctcgcctt ccaggccgtg
    14221 gacgacctgc tcggcatctg gggcgacccg gaggccaccg gcaagcagac ctggagcgac
    14281 ctgcgccagc gcaagaagtc cctcccggtc gtggccgcgc tcgcggccgg cggacccgcc
    14341 tccgagcggc tcggcgagat cctcgccgcc gacgccaaga ccagcgactt cgcgaacttc
    14401 tccgaggagg agttcgcggc ccgcgccgcc ctcatcgagg aagcgggcgg ccgggagtgg
    14461 accgccgacg aggcgcgccg tcagcacacc atcgccatcg aagccctcga cgccgtggac
    14521 atgcccgagc gggtgcggga ccgtttcacg gcactcgcgg acttcgtcgt cgtacgaaag
    14581 agatgatcac tatcggtcga atagccctcg cgtagtcgcc ggccggtgtc gcgggaacga
    14641 ccagcaccgg ccgacggcgg acccacagca gaagcaccac ttgcagactg cacgaagggg
    14701 aagccatgac agcgacgacc gacggaagca ccggggccac cctgaagccc ctcgcagccg
    14761 cggccagcga aaccgacgac atcacgatcc cccccgcggc ggccggggta ccagaagccg
    14821 ccgcccgcgc cacccggcgc gccacggact tcctgctctc cctgcaggac gcccagggct
    14881 ggtggaaggg cgacctcgag acgaacgtca cgatggacgc cgaggacctg ctcctgcgac
    14941 agttcctggg catcctcgac gaggagaccg cccgcgccgc cgccctgttc gtccgcggcg
    15001 agcagcgcga ggacggcacc tgggcgacct tctacgacgg tcccggcgac ctctccgcca
    15061 ccatcgaggc ctacgtcgcc ctgcgcctgg ccggcgacgc ccccgacacg ccgcacatgg
    15121 cgaaggccgc cgagtggatc cggtcccggg gcggcatcgc ggccgcccgc gtcttcaccc
    15181 ggatctggct ggccctgttc ggctggtgga agtgggacga cctgcccgaa ctcccgccgg
    15241 agctcatcta cttccccacc tgggtaccgc tcaacatcta cgacttcggc tgctgggccc
    15301 ggcagaccat cgtgccgctc accatcgtct ccgccaagcg gccggtgcgc cccgcgccct
    15361 tcgcgctgga cgaactgcac accgacccgg ccgtccccaa cccgccgcgg cccctggcac
    15421 cggcggcgag ctgggacggc gccttccagc gcctcgacag ggccctgcac gcctaccgca
    15481 gggtcgcccc gcgccggctg cgccgcgccg cgatgaacac cgccgcgcgc tggatcatcg
    15541 agcggcagga gaacgacggc tgctggggcg gcatccagcc cccggccgtg tactcggtca
    15601 tcgccctgta cctgctcggc tacgacctcg agcaccccgt gatgcgcgcg ggactggagt
    15661 ccctggaccg cttcgccgtg tggcgcgagg acggcgcccg gatgatcgag gcctgccagt
    15721 ccccggtgtg ggacacctgc ctggccgtca tcgcgctggc cgacgccggg gtgcccgccg
    15781 accacccgca actggtcaag gccgccgact ggatgctcgg tgaacagatc gtgcgccccg
    15841 gcgactggtc ggtgaagcgt cccggactgc cgcccggcgg ctgggcgttc gagttccaca
    15901 acgacaacta ccccgacatc gacgacaccg ccgaggtcgt cctcgcgctg cgccgggtcc
    15961 gccaccacga cccggagcgg gtcgagaggg ccatcggccg cggggtccgc tggaacctcg
    16021 gcatgcagtc gaagaacggc gcctggggcg cgttcgacgt cgacaacacc agcgccttcc
    16081 ccaaccggct gcccttctgc gacttcggcg aggtcatcga cccgccgtcc gcggacgtca
    16141 ccgcgcacgt cgtcgagatg ctcgcggtcg agggactcac ccatgacccg cgcacccggc
    16201 ggggcatcca gtggctgctg gccgaacagg aggcggacgg ctcgtggttc ggccgctggg
    16261 gcgtcaacta cgtctacggc accggctccg tcgtccccgc cctgacggcc gccggcctcc
    16321 ccgcctcgca ccccgccgtc cgccgcgcgg tgacctggct ggagtccgtc cagaacgacg
    16381 acggcggctg gggcgaggac ctgcgctcct accggtacgt cagggagtgg agcggccggg
    16441 gcgcctcgac cgcctcgcag accgcctggg cgctgatggc cctgctcgcg gcgggggagc
    16501 gggagtcgaa ggccgtcgaa cgcggcatcg cctggctggc cgccacccag cgggaggacg
    16561 gctcctggga cgagccgtac ttcaccggca ccggcttccc ctgggacttc tccatcaact
    16621 accacctcta ccggcaggtc ttcccgctca ccgccctcgg ccggtacgtg cacggcgacc
    16681 ccttcgccga gaaacacggc gtggggaacg ccgccgcccg cgccgagcag cccgccgccc
    16741 agacctcccc ggccgaggtg aagggcagct gatgaacgcg cagaccggcc cgtccccgct
    16801 gctgatcgcc tgcgcgctcg gcatcgagca cctcgccctg cgcaccggcg accgcggcgg
    16861 cgccggcgga ccggtcaccg tcctgcgcac cggcatgggc cccagggccg ccgagcgctc
    16921 ggtcacccgg gccctggccg aggacccgac gctcggcgac gccgtcgtgc tggccacggg
    16981 cttctgcgcg ggactcgccc ccggcatgca cccgggcgac ctggtcgtcg ccgaggagac
    17041 ccgggacccg cgctccaccg tcgcctgcgt cgggaccgac cggctggtga aggagctcgc
    17101 gcgggccctt ccccggcgca ccgtccacac cgggccgctc accggctcgg accacgtcgt
    17161 ccgcggcccc gagcgcgccg acctgctcgc caccggcgcg atcgccgtcg acatggagtc
    17221 cgcggccacg ctcctgagcg ccgtccgggc gggcgcgcgc ccggttgcgg ccgtccgggt
    17281 ggtcgtggac gctccagaac acgagctggt ccggatcggc acggtgcgcg gtggaatatc
    17341 agctttccgt gttctccgat ccgttcttcc cgcattcttc gaatggcacc gttcgttgct
    17401 gctcccccgg aggtgagccc agatggccat gccgcttcgt cagtccgtca aggtcgctac
    17461 gtacctggcc gaacagaaga tccgccgacg ggacaagttt ccgctcatcg tggagctgga
    17521 gccgcttttc gcctgcaacc tgaagtgcga gggatgcggc aagatccagc acccggcggg
    17581 ggtgctcaag cagcgcatgc cggtggcgca ggccgtcggg gcggtgctcg aatcgggtgc
    17641 gccgatggtc tccatcgccg gcggcgagcc gctgatgcac cctcagatcg acgagatcgt
    17701 acggcagttg gtggccaagc ggaagtacgt gttcctgtgc accaacgcct tgctcatgcg
    17761 caagaagatg gacaagttca agccctcgcc ctacttcgcc ttcgccgtgc acatcgacgg
    17821 gctgcgcgag cggcacgacg agtccgtggc caaggagggc gtgttcgacg aggcggtgga
    17881 ggccatcaag gaggccaagc ggcgcggctt ccgggtgacc accaactcga ccttcttcaa
    17941 caccgacacc ccgcagacca tcgtcgaggt cctcgactac ctcaacgacg acctcaaggt
    18001 cgacgagatg atgatctcgc ccgcctacgc ctacgagaag gcccccgacc aggagcactt
    18061 cctgggcgtg gagcagaccc gcgagctgtt caagaaggcc ttctcgggcg gcaaccgggc
    18121 ccgctggcgg ctcaaccact ccccgctgtt cctcgacttc ctcgagggca aggtcgactt
    18181 cccgtgcacc gcgtgggcga tcccgaacta ctccctgttc ggctggcagc gcccctgcta
    18241 cctgatgagc gacggctacg tcccgaccta ccgggagctg gtcgaggaga ccgactggga
    18301 caagtacggc cgcggcaagg acccgcgctg cgccaactgc atggcgcact gcggttacga
    18361 gcccaccgcc gtcctggcca cgatgggctc gctcaaggag tccctgcgcg ccctgcgcga
    18421 gaccgtctcc tcgaaccggg agtgacgtcg tgaccgccat ccccttgggc gtccccgagg
    18481 tgccggtccg gccgctcgcc gagcgacgtg tgtcgcggcg gatccaggtc ggaccggtgg
    18541 cggtcggggg cggggccccg gtgtcggtgc agtccatgac cacgacgcgt acgtcggaca
    18601 tcggtgcgac gctccagcag atcgcggagc tgaccgcgtc gggctgtcag atcgtgcggg
    18661 tggcctgtcc cacccaggac gacgcggacg cgttgccggt gatcgcgaag aagtcgcaga
    18721 tcccggtgat cgcggacatc cacttccagc ccaagtacgt cttcgcggcg atcgaggcgg
    18781 gctgcgcggc ggtgcgggtg aacccgggca acatcaagca gttcgacgac aaggtcaagg
    18841 agatcgcgaa ggcggcgaag gaccacggca cgccgatccg gatcggggtg aacgcgggtt
    18901 cgctggaccg gcggctgctg cagaagtacg gcaaggcgac gccggaggcg ctggcggagt
    18961 cggcgctgtg ggaggcctcg ctcttcgagg agcacgactt ccgggacatc aagatctcgg
    19021 tgaagcacaa cgacccggtc gtgatggtcg aggcctaccg gcagctcgcc gcgcagtgcg
    19081 actacccgct gcacctgggc gtcaccgagg cgggtccggc cttccagggc accatcaagt
    19141 cggccgtcgc cttcggcgcg ctgctctccc agggcatcgg tgacaccatt cgggtctcgc
    19201 tgtcggcgcc gccggtggag gagatcaagg tgggcatcca gatcctggag tcgctgaacc
    19261 tgcggcagcg gggtctggag atcgtctcct gtccgtcgtg cggccgtgcc caggtggacg
    19321 tctacaagct ggccgaggag gtcaccgccg gtctggaggg catggaggtg ccgctgcgcg
    19381 tcgccgtgat gggctgcgtg gtcaacggtc ccggtgaggc ccgcgaggcc gacctcggtg
    19441 tcgcctcggg caacggcaag ggacagatct tcgtcaaggg cgaggtcatc aagaccgtcc
    19501 ccgagtccaa gatcgtggag accctcatcg aagaggccat gaagatcgcc gaacagttgg
    19561 agaaggacgg cgcgtcgggg gagccggccg tcaccgtgag ctgaacagca cggaccgaag
    19621 ggggcccgag cgtgacgatg ctggagaaca tccggggacc acgcgacctg aaggcgctgt
    19681 ccgagacgga actcggtgaa ctgacccgcg agatacggga cttcctggtg cacgcggtcg
    19741 cccgcaccgg cggtcacctc ggacccaacc tgggggtggt ggaactcacc gtcgccctgc
    19801 accgggtctt cgagtcaccg gccgaccgca tcctgtggga caccggccac cagacctacg
    19861 tgcacaagct cctgaccggg cgtcaggact tctccaagct gcgcggcaag ggcgggctgt
    19921 ccggctaccc gtcgcgcgag gagtccgagc acgacgtcat cgagaacagt cacgcctcca
    19981 ccgtcctcgg ctgggccgac ggcctcgcca aggcccacca ggtcctcggc cgggaggacc
    20041 acgtcgtcgc ggtcatcggt gacggcgcgc tcaccggcgg catggcctgg gaggccctga
    20101 acaacatcgc ggcggccagg gaccggccgc tgatcatcgt cgtcaacgac aacgaacgct
    20161 cgtacgcgcc gaccatcggc ggcctcgcca accacctcgc gacgctccgc acgaccgacg
    20221 gctacgagcg cgtgctggcc tggggcaagg acgtcctcca gcgcaccccg gtggtcggca
    20281 acaccgtcta cgaggcactg cacggcgcga agaagggctt caaggacgcc ttcgccccgc
    20341 aggggctctt cgaggacctg gggctgaagt acctgggccc gatcgacggg cacgacatcg
    20401 aggccgtcga gtccgcgctg cggcgcgcca agcgcttcca cgggccggtg ctggtgcact
    20461 gcctcacgga gaagggccgt ggctacgagc ccgcgctgcg cgacgaggag gaccacttcc
    20521 acaccgtcgg cgcgatggac ccgctcacct gcgcgccgct cacgccgccc ccgggcccct
    20581 cctggacctc cgtgttcggc gaggagatgg tccggatcgg cgaggagcgc gacgacgtcg
    20641 tggcgatcac cgcggccatg ctgcacccgg tcggcctcgc cgccttcgcc gaacgcttcc
    20701 ccgaccgggt ctgggacgtc ggcatcgccg agcagcacgc cgccgtgtcc gccgccggcc
    20761 tcgccaccgg cggcctccac ccggtcgtcg ccgtctacgc caccttcctc aaccgggcct
    20821 tcgaccagct cctgatggac gtggccctgc accgctgcgg ggtcaccttc gtcctggacc
    20881 gggccggcgt gaccggcgtc gacggggcct cgcacaacgg cgtgtgggac atgtccgtcc
    20941 tccaggtcgt cccgggactg cgcatcgccg caccgcgcga cgccgaccag ctccgcgccc
    21001 agctgcgcga ggcggtcgcc gtcgacgacg cgccgaccct ggtgcgcttc ccgaaggagt
    21061 ccgtcggacc ggccgtcccc gccgtcggcc gggccggttc catggacgtc ctgcgcgccc
    21121 ccgaccggcc cgaggtgctg ctggtgtccg tcggcgtgat ggcgcccgtc tgcctgcggg
    21181 ccgccgagct gctcgaggcc cgcggcatcg ggtgcacggt cgtggacccg cgctgggtca
    21241 aacccgtcga cccggcgctc gcgcccctgg ccgcccggca ccggctggtg gccgtcgtcg
    21301 aggacaacag ccgcgcggca ggggtaggtt cggcggtggc actggcgctc ggtgacgcgg
    21361 acgtcgacgt acccgtacgc cgtttcggcg tccccgagca gttcctcgcg cacgccaagc
    21421 gcgccgaagt cctcgccgac atcggtctca cgccggtcga catcgccagc cggatcagcg
    21481 ccggtctggc cgtcgccgcg gagaccggag aacgtgccga agggcccacc ggcgacggac
    21541 ggaccgtcac gccagcgcaa ggagagaact gaatgaccaa ggagttcgac ctcgccgcgc
    21601 tcttggccga gcgcggagcc gagcggtacg agctgcacgc caagcacctc aaccaccagc
    21661 tgccgcgcat gctgcacacc atcggcttcg acaaggtcta cgagcgggcc gagggcgcgc
    21721 acttctggga cgcggacggc aacgactacc tggacatgct cgccgggttc gcggtgatgg
    21781 gcctcggacg ccaccacccc gtcgtccgca aggcgctgca cgacgtcctc gacgcctcgc
    21841 tggccgacct cacccgcttc gactgcccgc cgctgcccgg gctgctggcc gagcggctgc
    21901 tctcctacag tccgcacctg gaccgggtct tcttcggcaa cagcggcacg gaggcggtgg
    21961 agaccgcgct gaagttcgcc cggtacgcga ccggcaggcc gagggtcctg tactgctcgc
    22021 acgccttcca cgggctgacc accggctcgc tctccgtcaa cggcgagagc ggcttccgcg
    22081 acggcttcgc gccgctgctg cccgacacgg ccgtcccgct cggcgacctg gacgccctgg
    22141 cgcgggagtt gcggcgcggg gacgtggccg cgctgatcgt ggagccgatc cagggcaagg
    22201 gcgtgcacga ggccccgccc ggctacctgc gcgccgcgca ggacctgctg caccggcaca
    22261 aggcgctgct gatcgccgac gaggtgcaga ccgggctggg ccggaccggc acgttctacg
    22321 ccttccagca cgaggacgga gtcgagcccg acctggtgtg cgtggccaag gcgctgtccg
    22381 gcggctacgt gccggtgggg gccacgctgg gcagggactg gatcttccag aaggtctact
    22441 cctcgatgga ccgggtgcag gtccattcgg cgagcttcgg gtccaacgca caggccatgg
    22501 cggccggact cgcggtgctc tcggtgatgg agaacgagga gatcgtcgcg aacgccgccg
    22561 ccgtgggcga gcggctgaag tcccggctgg cggagctggt ggaccgctac gagatgctcg
    22621 ccgacgtgcg cggccggggg ctgatgatcg gcatcgagtt cggccgcccc aggtcactga
    22681 agctgcgcag ccgctggacg atgctccagg cggccaggaa gggactgttc gcgcagatgg
    22741 tggtggtgcc gctgctgcag cgccaccgga tcctcaccca ggtgtccggc gatcacctgg
    22801 aggtgatcaa gctgattccg ccgctgatca tcgacaccgc ggacgcggac cggttcgtcg
    22861 acgccttcac cgaggtgatg gaggacgcgc atcacggggg tggactgatg tgggacttcg
    22921 gcaagaccct ggtcaggcag gcggtggcca accgctgagc ccggcacttt tgccccacag
    22981 gcaagaaact tgcccgtggg gcaaggctcg ggctcaatgg aagcatgagc tcctccgaga
    23041 cgacggaccc ggccgaggga tcggtcgccg ccgtcgcacc ccagctgcgc gagctgcggc
    23101 gccgggccgc cctcaccctg gaggccgcgg cgcgcgccgc cgggctgtcg ccggcgcacc
    23161 tgtccaggct ggagaccggg cagcgccagc cctcgctgcc gatgctgctt tccctcgccc
    23221 gggtctacgg tacgaccgta tcggaactgc tcggcgagac ggccgcggac cgggacgccg
    23281 tcgtgcgggc cgaggccatg gagccgacgt ccgcgggcgg ctggacgtac tggcaggccg
    23341 gcgggtccgg ccgcgggatg caggccctgc gggtccgcgt cccgcacggg tcgcagggcg
    23401 acatcgtgcg ggtgcacccc ggtgaggagt ggctccacgt gctgcggggc cggctgcggc
    23461 tgcgcctcgg ggacaccgtg caccggctcg gtccgggcga cagcgcgcac ttcgactcgc
    23521 tgaccccgca ccggatcgcc gcccaggacg ccgacggggt cgagctcctc ttcgtccaca
    23581 ccctgctgca gagcccgacg gcggcgctct gcctggggcc ggccaccgtg ccgccccact
    23641 ccactccggg agagatgcca tgaacctgca ggacaagttc ccgcgtgccc tgtgggtgcg
    23701 gctcttcatc tacctcgtcg tgggccacgc cttcgcggcc ttcatctacc tgctcttcga
    23761 ggtgggagcc ggcagccggt gaacgcgacc cctcagtcca gcatccgctc gcgcagccgc
    23821 tcccgggtct gcggagtgat ccccaggccc tgctccaggt aggcgtcgac tccgccccag
    23881 gtctgctcga cggtctcgaa ggccgccgcg aggtactcgg cgcgcgcgtc gaacaggggg
    23941 ctgagcagct ccatgacctc gggggagtag gcggaggcgg cggtgctgct gcgacgcacc
    24001 ttgtagcggc ggtgcgtggc gttcgacttc aggtagtcct cgacgatggc gtcccgctcg
    24061 acgcccaggg cgaggagggt gatcgcgatc gacaggcccg cgcggtcctt gccggccgcg
    24121 cagtgcatca gcgccgggac gctgtcctcg gcgagcgcgt gcagcacccg cgagtgctcc
    24181 gccgtgcgct ccttgatgat caggcggtag gagccgatca tccgctcggc acccttgtcg
    24241 ccggccagga tctcgcgcag ctggtccagg tcgccgtcgc ggaccatctt ccagaactcg
    24301 gcaccgtcgg ccgggtcgct cagcggcagg ttcacattgc gcacgcccgg cagctcgacg
    24361 tccgggccct cgagcttctg gtcggccgcg ttgcggaagt cgaagatcgt gtgcaggccc
    24421 agcgaggcca ggaacgcggc gtcccctccg gtggcgtgcg ccaggtgacc gctgcggaac
    24481 agcactccct gtcgtacccg ccgtccgtcc acggtcggca ggccgcccac gtcacggaag
    24541 ttgcgcacac cggccagctc gggttcggtc gacgggacct gctgcgtcac gggggctcct
    24601 cccactccgc cccgtcggcg ctgctcgccg ccgggctcca ctcgaagata cggcacgggc
    24661 ctgcgcctcc gggtgccggg acgtccgaca gtggaccatc tgggccttct gtccgtattg
    24721 gtgccttagt cccaactcgc tctgaaataa aaggggctgg agggacggcg cgtgagcagc
    24781 gtcatatccg tgacggtgcg ttgcccgtca tgttcacgta attccgccgg ttttcaagga
    24841 cgtttgcccg aaccggtgcc ccgcgaatcg acggagggtg accggtgatt cccataaagg
    24901 atcaatcgga acaccggccg agggaacccc acgcttgtcg ctgcgcgtcc tggtcgctta
    24961 cgttcaccac cgatccggac ggaacgccta atcctgccgc cgaccggagc ccgcactcat
    25021 cgaccacccg tacacggcag gagcggggga cccacaggta agactgcctg ttccggttcc
    25081 cggaacggct tggggttaag ccgcgtcccg acgcggccgg gcatctccag ctcgcacccg
    25141 acagctcacc tcgcaggcgc cggagaggaa ttcgccatgc ccgcgaaggg taagcaccgc
    25201 cgtaccaggg ccatgcgcct gacccgcacc atcgccgtcg ccggaaccgg cggcgccgcg
    25261 ctcgcgctcc cgctgatggg cgccgccggg gcccacgccg ctcccgcgca gtccgtttcc
    25321 gagcactccg tgcagtccgt cgcgacgtcg gcgaagaagg ccgccggtgc ggagaagaac
    25381 ggggactcgc ggacgtacac cgtcaagagc ggtgactacc tctcgaagat cgccgacgag
    25441 caggacgtcg acggcggctg gaagaagctc tacgccgaca accgcgaggt cgtcggttcg
    25501 gacccgtcgc tgatccaccc cggtctgaag ctcgccgtcg ccggacaggc cgccaagtcc
    25561 tcggccccgt cctcctccgc cgcgtcggag aagccggcgg ccgagaagcc cgccgcggcc
    25621 gagaagcccg cccccgcgaa ggccgagtcg gccgagcagt cctcggacgc cgcgaagagc
    25681 tccgccgact cctcgaacac gagcgcccag tccgccggca ccggcagcgg cttcgcctcg
    25741 cccgtcccga gcggcaccct gggcaccccg taccaccaga cgggcagcat gtggtccagc
    25801 ggctaccaca ccggtacgga cttcgtcgtc ccgaccggca cctccctcaa ggccgtcggc
    25861 gcgggcaccg tcgtctccgc gggctggggc ggcgcctacg gcaaccaggt cgtcatccag
    25921 ctcgccgacg gccactacgc ccagtacgcc cacctctcct cgctctccgt ctccgcgggc
    25981 cagtccgtga cggcgggtca gcaggtcggc ctctcgggtg ccaccggcaa cgtgaccgga
    26041 ccgcacctgc acttcgagat ccgcaccacc ccggactacg gctcggacgt ggacccggtc
    26101 gcgtacctgc gctcgcacgg cgtctccctc tgacgaggag ctgacgcgcc ctcccgcgcc
    26161 accgaaggcc ggaccccgat ccccgggtcc ggccttcggt gtatcaggac cccgcttatt
    26221 ccggaattgg cgaatacttt aggcgtggca tttctcaccg cccgtcaacc ctttcctacg
    26281 gtcgcgtagg tcacattcca aggtgaatca tgggccgatg tggcagacga ttcgaagagt
    26341 gacagcggaa cagtgatcgg gtcgtacgtg gcggtggggg acagcttcac cgagggcgtc
    26401 ggcgaccggg gccccgacgg atcgttcgtc ggttgggccg accggttcgc cgtcctgctc
    26461 gcggaccggc gccccgaggg cgacttcacg tacacgaacc tcgccgtacg cggcaggctg
    26521 ctcgaccgga tcgtggcgga gcaggtgccg cgggccgtcg aactcgcccc cgacctggtc
    26581 tcgttctgtg cgggcggcaa cgacatcatc cggcccggca cggaccccga cgaggtggcc
    26641 gagcggttcg agcgggcggt ggccgcgctg accgccgcgg ccggcaccgt gctggtgacg
    26701 accgggttcg acacccgcgg ggtgcccgtc ctcaggcgtc tgcgcggcaa gatcgccacg
    26761 tacaacgggc ac
//
