LOCUS       NZ_CP012382            31131 bp    DNA     linear   CON 26-APR-2024
DEFINITION  Streptomyces ambofaciens ATCC 23877 chromosome, complete genome.
ACCESSION   NZ_CP012382
VERSION     NZ_CP012382.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces ambofaciens ATCC 23877
  ORGANISM  Streptomyces ambofaciens ATCC 23877
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8303940)
  AUTHORS   Thibessard,A., Haas,D., Gerbaud,C., Aigle,B., Lautru,S.,
            Pernodet,J.-L. and Leblond,P.
  TITLE     Complete genome sequence of Streptomyces ambofaciens ATCC 23877, the
            spiramycin producer
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8303940)
  AUTHORS   Thibessard,A., Haas,D., Gerbaud,C., Aigle,B., Lautru,S.,
            Pernodet,J.-L. and Leblond,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (29-JUL-2015) Faculte des Sciences et Technologies,
            Universite de Lorraine, Boulevard des Aiguillettes, Vandoeuvre les
            Nancy F-54506, France
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: CLC workbench v. 7.0.3
            Genome Coverage                   :: 114
            Sequencing Technology             :: Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001267885.1-RS_2024_04_26
            Annotation Date                   :: 04/26/2024 02:57:24
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,510
            CDSs (total)                      :: 7,418
            Genes (coding)                    :: 7,242
            CDSs (with protein)               :: 7,242
            Genes (RNA)                       :: 92
            rRNAs                             :: 5, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 72
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 176
            CDSs (without protein)            :: 176
            Pseudo Genes (ambiguous residues) :: 0 of 176
            Pseudo Genes (frameshifted)       :: 74 of 176
            Pseudo Genes (incomplete)         :: 131 of 176
            Pseudo Genes (internal stop)      :: 12 of 176
            Pseudo Genes (multiple problems)  :: 39 of 176
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 12:42:37
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6443951
            Orig. end                         :: 6475082
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP012382.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..31131
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="NI-siderophore"
                     /region_number="19"
                     /rules="IucA_IucC"
                     /tool="antismash"
     cand_cluster    1..31131
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="IucA_IucC"
                     /kind="single"
                     /product="NI-siderophore"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..31131
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[14000:17131]"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      14001..17131
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="IucA_IucC"
                     /neighbourhood="14000"
                     /product="NI-siderophore"
                     /protocluster_number="1"
     gene            113..514
                     /gene="uraH"
                     /locus_tag="SAM23877_RS28260"
                     /old_locus_tag="SAM23877_5950"
     CDS             113..514
                     /EC_number="3.5.2.17"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="uraH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030741.1"
                     /locus_tag="SAM23877_RS28260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5950"
                     /product="hydroxyisourate hydrolase"
                     /protein_id="WP_053139197.1"
                     /transl_table=11
                     /translation="MSTSTTASVSTHILDTSVGRPAEGVAVQLSARSGQDADWHELGGS
                     ATDADGRCKDLPALPEGTTHVRLGFETETYFAKKQAAAQQDAPALRDSENGRPVFFPEV
                     TITFAVVPGEHYHVPLLLNPFGYSVYRGS"
     gene            522..1457
                     /gene="pucL"
                     /locus_tag="SAM23877_RS28265"
                     /old_locus_tag="SAM23877_5951"
     CDS             522..1457
                     /EC_number="1.7.3.3"
                     /GO_function="GO:0004846 - urate oxidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0019628 - urate catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pucL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009191363.1"
                     /locus_tag="SAM23877_RS28265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5951"
                     /product="factor-independent urate hydroxylase"
                     /protein_id="WP_053139199.1"
                     /transl_table=11
                     /translation="MTRFVLGQNQYGKAENRVVKITRDGDTHHIKDLNVSVALSGDMEE
                     VHRSGSNANVLPTDTTKNTVFAFAKEHGIESAEDLGVKLARHFVDNNEPIHQARIRIEE
                     YGWERIETSKGGARFVGSEEIAHSFVRKGQETRVAQITYDGHGIQVLSGFKDLTVLNST
                     NSEFFGYLKDKYTTLKEDYDRILATTVSTWWRHNWDGVDSHAPDWDRSYNGVRKHALQA
                     FAETYSYSLQQTLFEMGVRVLNSRDEVDEIRFSMPNKHHFRSDLSPFGIDNEAKDGAVY
                     YAADRPYGLIEATILRDGAEQLIPVDMTNL"
     gene            1522..2934
                     /locus_tag="SAM23877_RS28270"
                     /old_locus_tag="SAM23877_5952"
     CDS             1522..2934
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015612350.1"
                     /locus_tag="SAM23877_RS28270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5952"
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="WP_053139202.1"
                     /transl_table=11
                     /translation="MALPAKGPAKGLDSTPPEHCEDAVTSVHPVDEKLHPSRLVPAALQ
                     HIAAMYAGVVTPPLIIGQAVGLDLEGRTRLIAASLLIAGVATLLQTLGVKGFVGNRLPF
                     VNAASSAGIAPILAIAETNSDGGQLPAIYGAVMVAGVFCLAVGPFFGRLLRFFPPLVTG
                     VVITLIGVTLMPVPVGWAQGGDETAADFGSMGNLALAAFTLAVILVMQRFGTGFLKQVA
                     LLFGLLVGTLVAIPAGMADFSALKSAPVAALPTPFAFGAPEFQPAAILSLCIVMLVLMT
                     ESSAGMLALGEICDRRADAKVITRGLRTDGLATLIGPVFGGFPTSAFAQNVGVVSLTRV
                     RSRYVVAVAGATLLVLGAFPVLGAVVSLVPMPVLGGAGIVLFGSIAVSGIRTLSEAGLD
                     DSSNIILVAVALGAGIIPLAAPTFYAEFPAWAQTVLGSGISAGALVAVTLNLFFHHLGT
                     RSRPTAPALKSS"
     gene            3007..4395
                     /locus_tag="SAM23877_RS28275"
                     /old_locus_tag="SAM23877_5953"
     CDS             3007..4395
                     /EC_number="3.5.4.32"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330155.1"
                     /locus_tag="SAM23877_RS28275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5953"
                     /product="8-oxoguanine deaminase"
                     /protein_id="WP_053139204.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.9e-61, bitscore:
                     205.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAASSAAERVVIENCAIATVDAGDTEYASGHVVLAGNRIESVGAG
                     AAPKDLENVVRRIDATGHLVTPGLVNTHHHFYQWITRGLATDHNLFNWLVALYPTWARI
                     DEPMAYAAAQGSLAMMARGGVTTAMDHHYVFPRGSGDLSGAIIRAASEMGVRFTLARGS
                     MDRGESDGGLPPDFAVESLDGALAATEATVREHHDSSFDAMTQVAVAPCSPFSVSTELM
                     RQGAELARRLGVRLHTHGSETVEEEKFCHELFGMGPTDYFESTGWLGEDVWMAHCVHMN
                     DSDIAAFARTRTGVAHCPSSNARLAAGIARVPDMLAAGVPVGLGVDGTASNESGELHTE
                     LRNALLINRLGAHREAALNARKALRLGTYGGAQVLGRAAETGSLEAGKLADLVLWRMDT
                     LAHSSIADPVTALVFGAAAPVTALFVNGRQIVEDGRLLTADEDAVARSTREQARRLAGI
                     AAQA"
     gene            4638..6023
                     /locus_tag="SAM23877_RS28280"
                     /old_locus_tag="SAM23877_5954"
     CDS             4638..6023
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494560.1"
                     /locus_tag="SAM23877_RS28280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5954"
                     /product="nucleobase:cation symporter-2 family protein"
                     /protein_id="WP_053139206.1"
                     /transl_table=11
                     /translation="MADHPVDEKLPPLKMATTGLQHVAAMYAGVVAPPLIVGAAIGLSA
                     TELTFLTGACLFTAGLATFLQTLGIWKIGARLPFVNGVTFAGVAPMTAIVASTEDKSDA
                     LPIIFGAVIVAGLLGFLFAPVFCKAIRFFPPVVTGTVITLIGISLLPVAFGWAQGSSPE
                     ADDFGSSTNLGLAAITLVIVLLLRRFTRGFVKQIAVLLGLVAGTLIAIPFGVTDFGPVA
                     DASVVGFPTPFHFGAPQFQLAAILSMCVVMVVSMTESTADMLALGEIVDRKADEKTIAA
                     GLRADTLGSAISPLFNGFMCSAFAQNIGLVAMTKIRSRYVVAAGGGFLVLMGLCPMAAS
                     LIAVVPRPVLGGAGVVLFGSVAASGIQTLVRASLDKDNNVLIVAVSLAVGIIPIAAPEF
                     YHSFPENAKIILDSGISTGCVAAVLLNLVFNHLGKGQDAEDVTHPMEAGEEITGATRAP
                     AGT"
     gene            complement(6111..7547)
                     /locus_tag="SAM23877_RS28285"
                     /old_locus_tag="SAM23877_5955"
     CDS             complement(6111..7547)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014675827.1"
                     /locus_tag="SAM23877_RS28285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5955"
                     /product="MFS transporter"
                     /protein_id="WP_053139209.1"
                     /transl_table=11
                     /translation="MTTMIESPARTQVGAPSRWRALVVLCAGALMTILDGNIVTVAMPA
                     IQADLGFSGPGLAWVVNAYLIPFGGLLLLAGRLGDLVGRKRMFTTGLALFTVASVLCGV
                     ATGQGLLIAARALQGLGGAMTMAVVLGMVVGLFPEPRERARAIAVFSAVGAAGGALGTF
                     LGGALTEALNWHWIFLINLPIGVLAWLAAVRVLAPDPSAGSVRGADYPGAALVTGALML
                     TVYTIVGAGDLGTSTTAVLAASALALFVAFTVRQGRVARPLLRLRLFRSRLLTGANAVQ
                     VLMVATMYGFQFIGALYLQRVLGYGELATGTAFLPAPVAIGVLMLGFSARTVGRFGAYR
                     VLLAGLTLIVAGLALLSRAPVDGSYVTDVLPPMLLLAVGFAAAMPALTGLAMAGVREED
                     AGLASGLFNTTQVVGGSLGLAVLSTLAAGRTEGLLGEGAAPVAATAEGYQLAFRVAVVV
                     AVAALVLAAVVLRERAGRGR"
     gene            7645..8046
                     /locus_tag="SAM23877_RS28290"
                     /old_locus_tag="SAM23877_5956"
     CDS             7645..8046
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656864.1"
                     /locus_tag="SAM23877_RS28290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5956"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_079030493.1"
                     /transl_table=11
                     /translation="MSQRNTGVTSQAVNAHACPVREVLDRVAGKWSVQILVAAAPGPIR
                     FTELERSIEGVSRRMLTLTLRNLERDGLVVRTVHPTVPPKVEYELTDVAQELYSSLRHL
                     TDWAERNRVYIAEARAAYDTEHRPELVDA"
     gene            complement(8060..8482)
                     /locus_tag="SAM23877_RS28295"
                     /old_locus_tag="SAM23877_5957"
     CDS             complement(8060..8482)
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0016790 - thiolester hydrolase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) 4HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972711.1"
                     /locus_tag="SAM23877_RS28295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5957"
                     /product="acyl-CoA thioesterase"
                     /protein_id="WP_053139212.1"
                     /sec_met_domain="4HBT_2 (E-value: 2.8e-21, bitscore: 74.9,
                     seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPFSVPVTVRGYETDTQGHVNQAVYLNYAEHARWSLLRAAGIR
                     QADLVARGVGPVALETTIRYRRELLAGDEVEVSCVFEWGEGRTFRIVQVVRKADGTVAA
                     EIEAVGGLMDLTARKLVADPRRRFGELASEPGLFGL"
     gene            complement(8564..9208)
                     /locus_tag="SAM23877_RS28300"
                     /old_locus_tag="SAM23877_5958"
     CDS             complement(8564..9208)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030745.1"
                     /locus_tag="SAM23877_RS28300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5958"
                     /product="hypothetical protein"
                     /protein_id="WP_053139214.1"
                     /transl_table=11
                     /translation="MALSPTAAQRRVIDAADPVTGRLRGTRAQLAALVKRGLAFRHPRP
                     PHDHFLTPAGHRIREAPAGPGEAPAPEPAAPAAGGVFAARVGGEETAAGDAGPARLREV
                     RGAWQGLLELRRMTHSDGSRDRPCAWERAHLVQAAALALEAAGLRPAGPGGGGGYRVRA
                     TPQPEAVAVHEPDPSALRGCATALEEAGWQVGEHTEPRTRERYLLASPRKV"
     gene            complement(9246..9845)
                     /locus_tag="SAM23877_RS28305"
                     /old_locus_tag="SAM23877_5959"
     CDS             complement(9246..9845)
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972709.1"
                     /locus_tag="SAM23877_RS28305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5959"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_053139216.1"
                     /transl_table=11
                     /translation="MGDLFLVRHGETEWSRSGRHTGLTDVPLTEQGREQARSLVPLIRS
                     HRIGAAFVSPFQRARETAELIGLHGVRVDPDLHEWDYGGYEGITTVEIHRSRPDWFLFT
                     DGVAPGPADRPGETPEQVGERADRVLARVEAAFADTEGCVVLVAHGHFLRVLTARHLGL
                     EPSHGALFQLGTGTLCRLGTEHGRPVVAAWNVRPPS"
     gene            complement(9880..11088)
                     /locus_tag="SAM23877_RS28310"
                     /old_locus_tag="SAM23877_5960"
     CDS             complement(9880..11088)
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (33-389). E-value:
                     7.7e-53. Score: 171.8. Matches aSDomain:
                     nrpspksdomains_SAM23877_RS28310_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_5"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007390030.1"
                     /locus_tag="SAM23877_RS28310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5960"
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="WP_053139218.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 8.9e-51, bitscore:
                     171.9, seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_5 (E-value: 2.9e-05, bitscore:
                     21.9, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2.3e-06,
                     bitscore: 25.9, seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFRQSNKLSEVCYEIRGPVIEQANALEEAGHSVLRLNTGNPALF
                     GFEAPEEIVQDMIRMLPQAHGYTDSRGVLSARRAVAQRYQALGLEVGVDDVFLGNGVSE
                     LVSMAVQALLEDGDEVLIPAPDFPLWTAVTTLAGGKAVHYLCDEQAEWYPDLADMESKI
                     TDRTKAVVLINPNNPTGAVYPKEIVEGILDLARRHGLMVFADEIYDQILYDDAVHHSAA
                     ALAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGPRQHARDYLEGLTMLASMRLCANAPAQ
                     YAIQAALGGRQSIRELTAPGGRLREQRDVAWEKLNEIPGVSCVKPKGALYAFPRIDPKV
                     HPIHDDERFVLDLLLREKIQVVQGTGFNWPGTDHFRILTLPHADDLEAAIGRIGRFLGG
                     YRQ"
     aSDomain        complement(9922..10989)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAM23877_RS28310_Aminotran_1_2.1
                     "
                     /evalue="7.70E-53"
                     /label="SAM23877_RS28310_Aminotran_1_2.1"
                     /locus_tag="SAM23877_RS28310"
                     /protein_end="389"
                     /protein_start="33"
                     /score="171.8"
                     /tool="antismash"
                     /translation="VLRLNTGNPALFGFEAPEEIVQDMIRMLPQAHGYTDSRGVLSARR
                     AVAQRYQALGLEVGVDDVFLGNGVSELVSMAVQALLEDGDEVLIPAPDFPLWTAVTTLA
                     GGKAVHYLCDEQAEWYPDLADMESKITDRTKAVVLINPNNPTGAVYPKEIVEGILDLAR
                     RHGLMVFADEIYDQILYDDAVHHSAAALAPDLVVLTFCGLSKTYRVAGFRSGWLVVTGP
                     RQHARDYLEGLTMLASMRLCANAPAQYAIQAALGGRQSIRELTAPGGRLREQRDVAWEK
                     LNEIPGVSCVKPKGALYAFPRIDPKVHPIHDDERFVLDLLLREKIQVVQGTGFNWPGTD
                     HFRILTLPHADDLEAA"
     gene            11176..11817
                     /locus_tag="SAM23877_RS28315"
                     /old_locus_tag="SAM23877_5961"
     CDS             11176..11817
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972704.1"
                     /locus_tag="SAM23877_RS28315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5961"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_053139221.1"
                     /transl_table=11
                     /translation="MPPRRSYDQYCSAARALDAVGDRWTLLIVRELLAGPRRYTDLHAD
                     LPGVSTDVLASRLREMEQGGLATRRRLPPPGAAYVYELTPRGSGLLPVLEALGAWGAGE
                     LGERRPTDAVRAHWFALPLRRALREAGAGEEVVEVGLDEGEFHLYAGTDGQGPVYGDGP
                     APQGAGARIVLDALTCAALGRGELSLRDAVRDGRVEVTGEGTTAKALREG"
     gene            complement(11861..12664)
                     /locus_tag="SAM23877_RS28320"
                     /old_locus_tag="SAM23877_5962"
     CDS             complement(11861..12664)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972703.1"
                     /locus_tag="SAM23877_RS28320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5962"
                     /product="hypothetical protein"
                     /protein_id="WP_053139223.1"
                     /transl_table=11
                     /translation="MRFRETLTVAVLLLGITAGPAAADASPTASPAEDGGAPTTAGTSF
                     RTATEIEQGRPATANGAAGDYLYWSFPADAGQRPTVRATVSLPETHAAETWRVDVYDGL
                     RRRQACQYGAQTRTAAAGAGSVELACVLRTVRAWSEPWANDPLPGTYYVRLTVVDLPTS
                     DLGVRVGAEVEVDSKDMGGASAVDGSLAEPLVPGAAVGPGADEEDAGRGAVLSAIEPED
                     GWSSGWWSDRWVWTGIGGVLAALAGVGGYALTRGSGRPSRVPPAA"
     gene            complement(12664..13938)
                     /locus_tag="SAM23877_RS28325"
                     /old_locus_tag="SAM23877_5963"
     CDS             complement(12664..13938)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385720.1"
                     /locus_tag="SAM23877_RS28325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5963"
                     /product="VWA domain-containing protein"
                     /protein_id="WP_053139225.1"
                     /transl_table=11
                     /translation="MITRTRLAAGACALVAALAAGIALPAGAAAGEPAGEDAPKVDLVL
                     DVSGSMRTRDIDGGTRMAAAKQAFNEVLDATPEEVRLGIRTLGADYRGDDRRTGCKDTA
                     RLYPVGPLDRTEAKTAVATLAPTGWTPIGPALLAAADDLDGGDGSKRIVLISDGEDTCA
                     PLDPCEVAREIAAKGIGLTIDTLGLVPNATMRQQLSCIAEATGGTYTSIEHTDELTDRV
                     NQLVDRAADPVVTPVATEGADVCTKAPTLESGLYTDREEFGQQRWYRVDVLPGQELRAS
                     VSVGADRAVNPSYGVLLRAVTVHGREIVRGEAAGEGRTDVISAGLRYPKADRDDADADK
                     PAAETVCLQVTHSFSAAEDVKSTPGLPLELTVDVVEGPGDADDVASFGLGRGWWLLGVL
                     VLAGFLAGLLWGWLSRWRFAVWRTN"
     misc_feature    complement(13946..13959)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.01"
                     /tool="antismash"
     gene            complement(14001..15500)
                     /locus_tag="SAM23877_RS28330"
                     /old_locus_tag="SAM23877_5964"
     CDS             complement(14001..15500)
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972701.1"
                     /locus_tag="SAM23877_RS28330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5964"
                     /product="IucA/IucC family siderophore biosynthesis
                     protein"
                     /protein_id="WP_053139226.1"
                     /sec_met_domain="IucA_IucC (E-value: 4.1e-32, bitscore:
                     110.4, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHRPPVAEAEVADELASVRPDLVARFAAELPGARAAVLSRLWRAF
                     AHEPMPWIADREPAGEELVLRLRDGRRLTGPAADPYRTGPYVRVVRLDGVAYDDPARLM
                     TELGVPHAAGFAAELGHSAASLALSYAGREDHPDEWPRSDWAWEQRVVDGHPYHPNCRS
                     RPGFSVAEQLAYGPEHGPVVGLGLVPVPATGCLVTGAWPRELRDGSRLLLPVHPWQAAH
                     VLRRPCEGRLAAHPLMSLRTLAVPGGPHVKTALSARLTSSVRDISVASVAASATLSSFG
                     EELAARMDGLLHVTRTLGAATAHSPDLAAVLRESPRDHAAAGEHVVPVAALATTGLPRS
                     PRWTAALARLALVVGLRALELGVALEAHGQNLLAVLSATGEPLRLVYRDLADIRVSPAR
                     LARHGVRTPELPSRMLTDDPDALRRKLFGSLVGGALASVAGSGAALRDALGAAVRELPR
                     TPDVVALCEAPLPVKALTLMRTSPGGSGDQWARLPNPLHWK"
     gene            15596..17131
                     /locus_tag="SAM23877_RS28335"
                     /old_locus_tag="SAM23877_5965"
     CDS             15596..17131
                     /GO_process="GO:0019290 - siderophore biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NI-siderophore: IucA_IucC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030750.1"
                     /locus_tag="SAM23877_RS28335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5965"
                     /product="IucA/IucC family protein"
                     /protein_id="WP_053139228.1"
                     /sec_met_domain="IucA_IucC (E-value: 1.3e-44, bitscore:
                     151.3, seeds: 168, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERVDFLPPPAGADAALRDDVAERADAYAAVPLLNCLLREVAEPL
                     PDTGARPVYRLPGGRLLRVRAGRRPAEPEVYAAGGWHRAGHTELVKLVAEELRRHTGLP
                     NHELPTEMTDSRDAVAALLTARARATPPDDPYVRSEQSLLTGHTHHPAPKARGGGPHAD
                     WLPYAPETHARFPLALLAVREDTVVDEGDTTALDALGEAPPGYRMLPAHPWQLRLASAA
                     LAPAFADGRIVRLGTTGFPVWPTAAVRTVYAPEYLPGRDLFLKFSLDVRITNDIRRLWR
                     HDLLRLRRTDTAVSEAFDVIGPPAAWLADRGHRTTDFAFEELAVVVRDGLRGRVLPGAT
                     PLLAAALVEGFPGNPLERTADPAAWWEAYLAAVVPPVLTAFADDGVVLEAHLQNTLVAV
                     DAAGTPAQALFRDAEGVKLLPETSRAAGWERLVYCLVVNHLCEIAGALAEHHPGLDPWP
                     AARRALARHDLPEIPALLASPTLPGKTNLLLRWTGADGADARYRPLPNPLREP"
     gene            17262..18176
                     /locus_tag="SAM23877_RS28340"
                     /old_locus_tag="SAM23877_5966"
     CDS             17262..18176
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972685.1"
                     /locus_tag="SAM23877_RS28340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5966"
                     /product="HipA family kinase"
                     /protein_id="WP_053142956.1"
                     /transl_table=11
                     /translation="MLRSVSATRYVTPLHSGGSVPGVVEADDLGTYVVKFTGSAQGRKA
                     LVAEVIVGELARELGLRVPELVLAHFDPGIAADEPHQEVRDLLDASAGLNLGMDYLSGG
                     ADLTPELAQDFSVGSGEAGRVVWLDALTVNVDRTVHSSNLMVWPTLGVAPARLWLIDHG
                     AALVFHHRWDASAPEKAYDFRHHALGRYAPDVRSADAELAPKVTEELLREVVARVPDDW
                     LTCEAGFDTPGEVRDAYVGYLSARVRASRDWLPTDFPSREELAAENAARAARTRRGRPD
                     WLKRVPDLHGKPSAAPDWSRHLS"
     gene            complement(18245..19867)
                     /gene="aceB"
                     /locus_tag="SAM23877_RS28345"
                     /old_locus_tag="SAM23877_5967"
     CDS             complement(18245..19867)
                     /EC_number="2.3.3.9"
                     /GO_function="GO:0004474 - malate synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="aceB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020133434.1"
                     /locus_tag="SAM23877_RS28345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5967"
                     /product="malate synthase A"
                     /protein_id="WP_053139230.1"
                     /transl_table=11
                     /translation="MSAPAPSTLAIVDAEPLPRQEEVLTDAALAFVAELHRRFTPRRDE
                     LLTRRAERRAEIARTSTLDFLPETAAVRADDSWKVAPAPAALQDRRVEITGPTDRKMTI
                     NALNSGARVWLADFEDASAPTWENVVLGQLNLTAAYTRTIDFTDERTGKSYALRPDEEL
                     ATVVMRPRGWHLDERHLQVDGRAVPGALVDFGLYFFHNAQRLLDLGKGPYFYLPKTESH
                     LEARLWNEVFVFAQDYVGIPQGTVRATVLIETITAAYEMEEILYELRDHAAGLNAGRWD
                     YLFSIVKNFRDGGARFVLPDRNAVTMTAPFMRAYTELLVRTCHKRGAHAIGGMAAFIPS
                     RRDAEVNKVAFEKVRADKDREANDGFDGSWVAHPDLVPIAMESFDKVLGDKPHQKDRLR
                     EDVDVRAADLIAIDSLDAKPTYAGLVNAVQVGIRYIEAWLRGLGAVAIFNLMEDAATAE
                     ISRSQIWQWINAEVVLDNGEQVTAELARKVAAEELANVRAEIGDEAFAAGNWQQAHDLL
                     LTVSLDEDYADFLTLPAYEQLKG"
     gene            complement(20086..20685)
                     /locus_tag="SAM23877_RS28350"
                     /old_locus_tag="SAM23877_5968"
     CDS             complement(20086..20685)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007385730.1"
                     /locus_tag="SAM23877_RS28350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5968"
                     /product="nucleotidyltransferase family protein"
                     /protein_id="WP_053139232.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.6e-35, bitscore:
                     119.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNEDQVAGVLLAAGGGRRLGGRPKALLEHHGHPLVEHAIAALR
                     AAGCTRVHVVLGARAEEVRARAALDGCVLVDNPAWEEGMGSSLCAGLGSLAGTGARAAL
                     VSLVDQPGIGARAMARVRAGYRDETSLASAAYAGVRGHPVLLGAAHWAGVSATATGDRG
                     ARAYLREHEAEIALVECGDVALPYDIDTAADLHHLE"
     gene            20887..21201
                     /locus_tag="SAM23877_RS28355"
                     /old_locus_tag="SAM23877_5969"
     CDS             20887..21201
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972682.1"
                     /locus_tag="SAM23877_RS28355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5969"
                     /product="DUF5955 family protein"
                     /protein_id="WP_053139233.1"
                     /transl_table=11
                     /translation="MLRSLGQGQVTVGDEDVRVTALRTAVSRLRRQLALLRADFPDRAV
                     AEDELADLAAMTAHGVPEVSRLHRSLLLIVGAIGSVSALSRGLTEVRQAVELFGDPPRR
                     "
     gene            complement(21389..22192)
                     /gene="allR"
                     /locus_tag="SAM23877_RS28360"
                     /old_locus_tag="SAM23877_5970"
     CDS             complement(21389..22192)
                     /codon_start=1
                     /gene="allR"
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972681.1"
                     /locus_tag="SAM23877_RS28360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5970"
                     /product="allantoin degradation transcriptional regulator
                     AllR"
                     /protein_id="WP_053139235.1"
                     /transl_table=11
                     /translation="MPTSSASTTDSARSATGGVQSLERAFDLLERMADAGGEVGLSELS
                     ASSGLPLPTIHRLMRTLVACGYVRQQPNRRYALGPRLIRLGESASRLLGTWARPHLARL
                     VEETGETANMALLDGDEIVYVAQVPSKHSMRMFTEVGRRVLPHSTGVGKALLADFPADE
                     VRALLGRTGMPAATEKTITTPDGFIAALADVRRQGYAIDDNEQEIGVRCLAVSVPNSPT
                     AAAISISGPAGRVTEAATDRMVPLLQQVAAELSEALLASNGTPAA"
     misc_feature    22281..22297
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.46"
                     /tool="antismash"
     gene            22436..23773
                     /gene="allB"
                     /locus_tag="SAM23877_RS28365"
                     /old_locus_tag="SAM23877_5971"
     CDS             22436..23773
                     /EC_number="3.5.2.5"
                     /GO_function="GO:0004038 - allantoinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0050897 - cobalt ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="allB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007388114.1"
                     /locus_tag="SAM23877_RS28365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5971"
                     /product="allantoinase AllB"
                     /protein_id="WP_053139237.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.8e-26, bitscore:
                     90.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEAELVLRSTRVVTPEGTRAASIAVTGEKITAVLPYDAPVPAGA
                     RLEDVGDHVVLPGLVDTHVHVNDPGRTEWEGFWTATRAAAAGGITTLVDMPLNSIPPTT
                     TVENLRTKREVAADKAHIDVGFWGGALPDNVKDLRPLHESGVFGFKAFLSPSGVDEFPH
                     LDQEQLARSLAEIAAFDGLLIVHAEDPHHLAAAPQQGGPKYSHFLASRPRDAEDTAIAG
                     LLAQAKRLGARVHVLHLSSSDALPLIAEARAEGVRVTVETCPHYLTLTAEEVPDGASEF
                     KCCPPIREAANQDLLWQALVDGTIDCVVTDHSPSTADLKTDDFATAWGGIAGLQLSLPA
                     MWTKARERGLGLEDIVRWMSANTASQVGLDGRKGAIAAGHDADFAVLAPDETFTVDPAA
                     LQHRNRVTAYAGKTLYGVVKSTWLRGRRVVADGAFTEPKGQLLDRA"
     gene            23836..24966
                     /gene="alc"
                     /locus_tag="SAM23877_RS28370"
                     /old_locus_tag="SAM23877_5972"
     CDS             23836..24966
                     /EC_number="3.5.3.4"
                     /GO_function="GO:0004037 - allantoicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003972679.1"
                     /locus_tag="SAM23877_RS28370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5972"
                     /product="allantoicase"
                     /protein_id="WP_053139239.1"
                     /transl_table=11
                     /translation="MTAQQNPSLASFTGDANPYGGGDPYADYRTADLPFTQYANLADRQ
                     LGAGVVAANDEFFAQRENLLVPEPAEFDPEHFGHKGKVMDGWETRRRRGASAEHPWPTE
                     DDHDWALIRLGAPGVIRGIVVDTAHFRGNYPQAVSVEGTSVAGSPSPEELLADDVKWTT
                     LVPRTAVGGHAANGFAVLAEQRFTHLRLKQHPDGGIARLRVYGEVVPDPAWLTALGTFD
                     VVALENGGQVEDASNLFYSPATNTIQPGRSRKMDDGWETRRRRDQGNDWIRYRLVDRSQ
                     IRAVEIDTAYLKGNSAGWASVSVKDGEDGEWREILPRTRMQPDTNHRFVLPETAVGTHA
                     RVDIFPDGGISRLRLFGSLTEDGAAHLAARHQELGG"
     gene            complement(25039..25803)
                     /locus_tag="SAM23877_RS28375"
                     /old_locus_tag="SAM23877_5973"
     CDS             complement(25039..25803)
                     /NRPS_PKS="Domain: PKS_KR (17-191). E-value: 1.2e-13.
                     Score: 43.3. Matches aSDomain:
                     nrpspksdomains_SAM23877_RS28375_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030766.1"
                     /locus_tag="SAM23877_RS28375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5973"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_053139241.1"
                     /sec_met_domain="adh_short (E-value: 5.2e-33, bitscore:
                     113.3, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTNTLTHPTLPPLTGRTALVTGGSRGIGAATVLRLAREGADVAL
                     TYVNGKEAAEDVVRAVEALGRRAVALRADAGDADEAAGAVERAADALGGLDVLVNNAGV
                     GLLGPVEGFSVGDLDRVLAVNVRGVFLTAQAAAARMTAGGRIITVGSCMAQRVPGPGGT
                     LYAMSKSALIGLTKALARELGGRGITANIVHPGPIDTDMNPAGGPYAEGQAALTALGRF
                     GTAEEVASTVAHLATAGYVTGAEFSVDGGHAA"
     aSDomain        complement(25231..25752)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_SAM23877_RS28375_PKS_KR.1"
                     /evalue="1.20E-13"
                     /label="SAM23877_RS28375_PKS_KR.1"
                     /locus_tag="SAM23877_RS28375"
                     /protein_end="191"
                     /protein_start="17"
                     /score="43.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGGSRGIGAATVLRLAREGADVALTYVNGKEAAEDVVRAVE
                     ALGRRAVALRADAGDADEAAGAVERAADALGGLDVLVNNAGVGLLGPVEGFSVGDLDRV
                     LAVNVRGVFLTAQAAAARMTAGGRIITVGSCMAQRVPGPGGTLYAMSKSALIGLTKALA
                     RELGGRGITAN"
     CDS_motif       complement(25681..25746)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_SAM23877_RS28375_0001"
                     /evalue="5.10E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="SAM23877_RS28375"
                     /protein_end="41"
                     /protein_start="19"
                     /score="15.9"
                     /tool="antismash"
                     /translation="LVTGGSRGIGAATVLRLAREGA"
     gene            25965..26360
                     /locus_tag="SAM23877_RS28380"
                     /old_locus_tag="SAM23877_5974"
     CDS             25965..26360
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020119054.1"
                     /locus_tag="SAM23877_RS28380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5974"
                     /product="ribonuclease"
                     /protein_id="WP_053139243.1"
                     /transl_table=11
                     /translation="MRFPPRAARLGAAAAVLSALLVGGTVSATTAGAAPAAVGDICLSD
                     LPSQAHDTLDLIEQGGPYPFEQDGTVFQNREGILPDRSTGYYHEYTVITPGSDTRGARR
                     IVTGEQTREDYYTADHYASFDLVDHGC"
     gene            complement(26394..26591)
                     /locus_tag="SAM23877_RS28385"
                     /old_locus_tag="SAM23877_5975"
     CDS             complement(26394..26591)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010038960.1"
                     /locus_tag="SAM23877_RS28385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5975"
                     /product="hypothetical protein"
                     /protein_id="WP_053139246.1"
                     /transl_table=11
                     /translation="MKELLEFLGLMAVIQGVAGLVHEFTDWNWGVVQRIGVLDGYEVYA
                     SVVLLALGGALFAAAESRRG"
     gene            26771..28021
                     /locus_tag="SAM23877_RS28390"
                     /old_locus_tag="SAM23877_5976"
     CDS             26771..28021
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003996670.1"
                     /locus_tag="SAM23877_RS28390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5976"
                     /product="histidine kinase"
                     /protein_id="WP_053139248.1"
                     /transl_table=11
                     /translation="MNSDKQATTPPAFAKRRWVLPAALVEDMYPQSRRADGRPRRTGRD
                     WIVDFTCFLLAVGVGLLAADTLDQEPNLPRSMELADQVVGALACAAVWLRRRWPVGLAV
                     AMVPVSMVSATSGGAALLSLFTLAVHRPFRYTAWIGGASLALMPLYFWMRPEPDLPFLA
                     SLVIASLLAVAIVGWGLLVRSKRQLLLSLRDRARRAENEARLRAEQAQRLAREAIAREM
                     HDVLAHRLTLLSVHAGALEFRPDASREEVARAAGVIRESSHEALQDLREIIGVLRAGES
                     DDAGRPQPTLAALDALVAECREAGMKITLAGRVTDPAGVPASVGRTAYRVAQEALTNAR
                     KHAPGTEVSVSVAGAPGEGLSLSVRNAPPVGEVPPVPGSGQGLIGLTERATLAGGTLEH
                     GPTSEGGFEVRTRLPWG"
     gene            28090..28770
                     /locus_tag="SAM23877_RS28395"
                     /old_locus_tag="SAM23877_5977"
     CDS             28090..28770
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019330179.1"
                     /locus_tag="SAM23877_RS28395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5977"
                     /product="response regulator transcription factor"
                     /protein_id="WP_053139249.1"
                     /transl_table=11
                     /translation="MTAIRLLLVDDDPLVRAGLSFMLGGADDVEIVGEAADGDQVEALV
                     DRTRPDVVLMDIRMPVVDGLTATERLRSRPDAPQIVVLTTFHADEQVLRALRAGAAGFV
                     LKDTPPAEILDAVRRVAAGDPVLSPAVTRRLMAHAAGGTADTRRTRARARVTALNDRER
                     EVAVAVGRGMANAAIAAELFMSVATVKTHVSRILAKLDLDNRVQIALLAHDAGLLDEYG
                     EEAR"
     gene            complement(29140..30162)
                     /locus_tag="SAM23877_RS28400"
                     /old_locus_tag="SAM23877_5978"
     CDS             complement(29140..30162)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GFO_IDH_MocA_C3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004923018.1"
                     /locus_tag="SAM23877_RS28400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5978"
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="WP_053139251.1"
                     /sec_met_domain="GFO_IDH_MocA (E-value: 3.7e-19, bitscore:
                     68.3, seeds: 39, tool: rule-based-clusters)"
                     /sec_met_domain="GFO_IDH_MocA_C3 (E-value: 1.5e-23,
                     bitscore: 81.9, seeds: 4226, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIGVIGTGRIGTVHANTLSRHRDVGSLILTDADLGRAQDLAHRL
                     GETAAPGVDEIFRWGVDAVVITTATAAHAELIGRAARSGLPVFCEKPIALDVPGTLQAI
                     AEVEAAGTVLQMGFQRRFDAGYTGAREAVRSGRLGRLHTVRAVTSDQAPPPTAYLPQSG
                     GLYRDTLIHDFDVLRWVTGREVTDVYAAGSDAGPPMFRAADDVDTGAALLTLDDGTLAT
                     VTATRLNGAGYDVRMELAGELDQIVVGLDDRTPIASTEPTGPPAADKPWTGFVERFGPA
                     YEAELAAFVQVVRGERANPCDGREALRALLIAEACEISRRERRPVRPAEVPGAGASATG
                     "
     misc_feature    30203..30217
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.66"
                     /tool="antismash"
     gene            30292..31029
                     /locus_tag="SAM23877_RS28405"
                     /old_locus_tag="SAM23877_5979"
     CDS             30292..31029
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011030772.1"
                     /locus_tag="SAM23877_RS28405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SAM23877_5979"
                     /product="myo-inositol degradation transcriptional
                     regulator"
                     /protein_id="WP_079030814.1"
                     /transl_table=11
                     /translation="MSLDLSVDRSSPVPLYFQLSQQLEAAIEHGALTPGSLLGNEIELA
                     ARLGLSRPTVRQAIQSLVDKGLLVRRRGVGTQVVHSKVKRPLELSSLYDDLEAAGQRPA
                     TKVLVNTVVPATAEVAAALGVVQESDVHRVERLRLAHGEPMAYLCNHLPPGLVDLDTGQ
                     LEATGLYRLMRAAGITLHSARQSIGARAATADEAERLGEDVGAPLLTMERTTFDDTGRA
                     VEFGTHTYRPSRYSFEFQLLVRP"
     misc_feature    31068..31082
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.24"
                     /tool="antismash"
     misc_feature    31073..31087
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.7"
                     /tool="antismash"
     misc_feature    complement(31086..31101)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
ORIGIN
        1 tcaaggagcg gatcgggaac tcgcccgagc aggagcggga gatcgtccgc accgaactgg
       61 ggaagatcaa ccgcatccgc ctgaaccgac tcgtcgaaca ggacgcctga ccatgagcac
      121 cagcaccacc gcctccgtgt ccacgcacat cctggacacc agcgtcggcc gccccgccga
      181 gggcgtcgcc gtccagctct ccgcccggtc cgggcaggac gcggactggc acgagctcgg
      241 cggctccgcg accgacgcgg acggccggtg caaggacctc ccggccctgc cggagggcac
      301 cacacacgta cggctcggct tcgagaccga gacgtacttc gccaagaaac aagccgcggc
      361 ccagcaggac gcccccgcgc tccgggacag cgagaacggc cggcccgtgt tcttccccga
      421 ggtcaccatc accttcgcgg tggtgcccgg cgagcactac cacgttccgc tgctgctcaa
      481 cccgttcggc tactccgttt accgagggag ctgaccgaca catgacccgt ttcgtcctgg
      541 gacagaacca gtacggcaag gcagagaacc gcgtcgtcaa gatcacgcgc gacggcgaca
      601 cgcaccacat caaggacctg aacgtctccg tcgccctctc cggcgacatg gaggaggtcc
      661 accgcagcgg gtccaacgcg aacgtcctgc cgaccgacac caccaagaac acggtgttcg
      721 ccttcgccaa ggagcacggc atcgagagcg ccgaggacct cggcgtcaag ctcgcccgcc
      781 acttcgtcga caacaacgag ccgatccacc aggcccgcat ccgcatcgag gagtacggct
      841 gggagcggat cgagacctcg aagggcggag cccgcttcgt cggctccgag gagatcgccc
      901 actccttcgt ccgcaagggc caggagaccc gcgtcgcgca gatcacctac gacggccacg
      961 gcatccaggt gctctccggc ttcaaggacc tgaccgtcct gaactcgacc aactccgagt
     1021 tcttcggcta cctgaaggac aagtacacca ccctcaagga ggactacgac cggatcctcg
     1081 ccaccaccgt ctccacctgg tggcggcaca actgggacgg cgtcgactcg cacgccccgg
     1141 actgggaccg ctcgtacaac ggtgtgcgca agcacgcgct gcaggcgttc gccgagacct
     1201 actcgtactc gctccagcag accctcttcg agatgggcgt gcgggtgctc aactcccgcg
     1261 acgaggtgga cgagatccgc ttctcgatgc ccaacaagca ccacttccgc tcggacctgt
     1321 cgcccttcgg gatcgacaac gaggccaagg acggcgccgt ctactacgcc gccgaccgcc
     1381 cctacggcct gatcgaggcc accatcctgc gcgacggcgc cgagcaactc atcccggtcg
     1441 acatgaccaa cctctgacgc ggaaagcgcg cccccggccg ggcatccgga cccgggggcg
     1501 cgccacaccg gaggaaacac catggcactg cctgcgaaag ggcccgccaa aggcctggat
     1561 tccaccccgc cggagcactg cgaggacgcc gtcacgtccg tgcacccggt ggacgagaag
     1621 ctccacccct cgcggctcgt ccccgccgcg ctccagcaca tcgccgccat gtacgcgggt
     1681 gttgtcactc ctccgctcat catcggccag gccgtcggac tcgacctcga gggccgcacc
     1741 cggctgatcg ccgcgagcct gctcatcgcg ggcgtcgcga ccctgctcca gaccctcggc
     1801 gtcaagggct tcgtcggcaa ccgcctgccc ttcgtcaacg ccgcctcctc ggccggcatc
     1861 gcacccatcc tcgccatcgc cgagacgaac agcgacggtg gccaactccc ggccatctac
     1921 ggcgcggtga tggtcgcggg cgtcttctgc ctcgccgtcg gcccgttctt cggccggctg
     1981 ctccgcttct tcccacccct ggtcaccggc gtggtgatca ccctcatcgg ggtcacgctg
     2041 atgccggtcc cggtcggctg ggcccagggc ggcgacgaga ccgccgccga cttcggctcc
     2101 atgggcaacc tcgcgctcgc cgcgttcacc ctcgccgtca tcctcgtcat gcagcgcttc
     2161 ggcacgggct tcctgaagca ggtcgccctg ctcttcggcc tgctcgtcgg caccctggtc
     2221 gccatcccgg ccggcatggc ggacttcagc gccctgaagt cggcgccggt cgccgcgctg
     2281 cccaccccct tcgccttcgg cgcccccgag ttccagcccg cggccatcct gtcgctgtgc
     2341 atcgtgatgc tggtcctgat gaccgagtcc agcgccggca tgctcgccct cggcgagatc
     2401 tgcgaccgcc gcgccgacgc caaggtcatc acccgcggcc tgcgcaccga cggcctcgcc
     2461 acgctgatcg gccccgtctt cggcggcttc cccacctccg ccttcgcaca gaacgtcggc
     2521 gtggtctccc tcacccgggt acgcagccgc tacgtcgtcg ccgtcgcggg cgccaccctg
     2581 ctggtcctcg gcgccttccc ggtcctcggc gcggtcgtct ccctcgtccc catgccggtc
     2641 ctcggcggcg cgggcatcgt gctcttcggc tcgatcgccg tcagcggcat ccgcaccctg
     2701 tccgaggcgg ggctggacga cagctccaac atcatcctgg tggccgtggc cctcggcgcg
     2761 ggcatcatcc cgctggccgc gccgaccttc tacgccgagt tccccgcctg ggcgcagacc
     2821 gtgctcggct ccggcatcag cgccggcgcg ctcgtcgcgg tcacgctcaa cctgttcttc
     2881 caccatctcg gcacccggag ccgtccgacg gctccggcac tcaaatcctc ctagggtcct
     2941 gccgtgccct ccccgtgggt actcacttcc ccgcccatgg gccccactga aagacaagga
     3001 agcagcatgg cagcatcatc ggcagccgag cgcgtggtca tcgagaactg cgcgatcgcc
     3061 acggtggacg cgggcgacac cgagtacgcc tcgggccacg tcgtcctcgc gggcaaccgg
     3121 atcgagtccg tcggcgcggg agcggcgccc aaggacctgg agaacgtcgt acgccggatc
     3181 gacgcgaccg gccacctggt cacgcccggc ctggtcaaca cccaccacca cttctaccag
     3241 tggatcaccc ggggcctggc caccgaccac aacctgttca actggctggt cgccctctac
     3301 ccgacgtggg cgcgcatcga cgagccgatg gcgtacgcgg cggcccaggg ctccctcgcc
     3361 atgatggccc gcggcggcgt caccaccgcc atggaccacc actacgtctt cccgcgcggc
     3421 tccggcgacc tgtccggcgc gatcatccgc gccgcgagcg agatgggcgt ccgcttcacc
     3481 ctcgcccgcg gttcgatgga ccgcggcgag tccgacggcg ggctgccgcc ggacttcgcg
     3541 gtggagagcc tggacggtgc gctggccgcc accgaggcca ccgtcaggga acaccacgac
     3601 tcctccttcg acgcgatgac ccaggtcgcc gtcgccccct gctccccctt ctccgtctcc
     3661 accgaactga tgcgccaggg cgccgagttg gcccgccggc tcggcgtgcg gctgcacacc
     3721 cacggttcgg agaccgtgga ggaggagaag ttctgccacg agctgttcgg catgggtccc
     3781 accgactact tcgagtccac cggctggctc ggcgaggacg tgtggatggc gcactgcgtc
     3841 cacatgaacg actccgacat cgccgccttc gcccgcacga ggaccggtgt ggcgcactgt
     3901 ccctcctcca acgcccggct ggccgcgggg atcgcgcggg tgcccgacat gctcgccgcc
     3961 ggcgtcccgg tcggcctcgg tgtggacggc accgcctcca acgagtccgg tgaactccac
     4021 accgagctgc ggaacgccct gctcatcaac cgcctcggcg cccaccgcga ggccgcgctg
     4081 aacgcccgca aggcgctgcg cctgggcacc tacggcggcg cgcaggtact cggccgtgcc
     4141 gccgagacgg gctccctgga ggcgggcaag ctcgccgacc tggtgctgtg gcggatggac
     4201 accctcgccc actcctccat cgccgacccg gtgaccgccc tggtcttcgg cgccgccgcc
     4261 ccggtcacgg cgttgttcgt caacggccgc cagatcgtcg aggacggccg gctgctcacg
     4321 gccgacgagg acgccgtcgc ccgctccacc cgggagcagg cgcggcgcct ggcggggatc
     4381 gccgcgcagg cctgaacgaa ccacagctga acaccacctg atctccggcc gagagggacg
     4441 gctctctgcc ggtagccgtg gacccgagcg gggtccatgg cggccgtctc cgggggcgtg
     4501 cgtccatacg cacgccccgg gagcggtcac cgtttcccca gacggtccgt cacggtcccg
     4561 cacgaccgtc accacccgca ccacctccat gacacccgcg tcagagacga cgcgtaaccg
     4621 accggaggga cgccgccgtg gccgaccacc ccgtagacga gaaactcccg cccctgaaga
     4681 tggcgacgac cggcctccag cacgtggccg ccatgtacgc cggagtagtc gcaccacccc
     4741 tgatagtcgg cgcggccata gggctgtccg cgaccgagct caccttcctc accggcgcct
     4801 gcctgttcac cgccggcctc gccaccttcc tgcagaccct cggcatctgg aagatcggtg
     4861 cccggctgcc cttcgtcaac ggcgtcacct tcgcgggtgt cgcccccatg accgcgatcg
     4921 tcgcctccac cgaggacaag tccgacgcgt tgcccatcat cttcggcgcc gtcatcgtcg
     4981 ccggtctgct gggctttctg ttcgcccccg tcttctgcaa ggcgatccgc ttcttcccgc
     5041 cggtcgtcac cggcacggtc atcaccctga tcggcatctc cctgctgccc gtcgccttcg
     5101 gctgggcgca gggctccagt ccggaggcgg acgacttcgg ttcctcgacc aacctgggcc
     5161 tggcggcgat caccctcgtc atcgtcctgc tgctgcgccg cttcacccgc ggcttcgtca
     5221 agcagatcgc cgtgctgctc ggcctggtcg cgggcaccct catcgcgatc cccttcggcg
     5281 tcacggactt cgggccggtc gcggacgcga gcgtcgtcgg cttcccgacc ccgttccact
     5341 tcggcgcccc gcagttccag ctcgccgcga tcctctccat gtgcgtggtg atggtggtct
     5401 cgatgaccga gtccaccgcc gacatgctcg ccctgggcga gatcgtggac cgcaaggccg
     5461 acgagaagac catcgcggcc ggcctgcgcg ccgacaccct cggctcggcc atcagcccgc
     5521 tcttcaacgg cttcatgtgc agcgccttcg cgcagaacat cggcctggtc gcgatgacga
     5581 agatccgcag ccgctacgtc gtcgccgcgg gcggcggctt cctggtgctg atggggctgt
     5641 gtcccatggc ggcctcgctc atcgccgtcg tcccccgccc ggtgctcggc ggcgccggcg
     5701 tggtcctctt cggctccgtc gcggccagcg gcatccagac cctggtccgg gcgagcctcg
     5761 acaaggacaa caacgtcctg atcgtggcgg tttccctggc cgtcggcatc atcccgatcg
     5821 cggcaccgga gttctaccac tcgttcccgg agaacgcgaa gatcatcctc gactcgggca
     5881 tctcgaccgg ttgcgtggcc gccgtcctgc tcaacctggt cttcaaccac ctgggcaagg
     5941 gacaggacgc ggaggacgtc acccatccga tggaggcggg ggaggagatc accggcgcga
     6001 cccgggcccc ggccgggacg tgaggccggc accgggcgac ccccgggcgt tacgggggcc
     6061 ggcgcctctc cccggaggcg ccggccctca cctgtcgtgg ccctcgaggg tcacctgccc
     6121 cgtccggcac gctcccgcag gaccaccgcc gccagcacca gcgccgccac cgcgacgacc
     6181 accgccaccc ggaaggccag ttggtacccc tcggccgtcg ccgccaccgg cgccgcgccc
     6241 tcgccgagca gcccctcggt ccggcccgcg gccagcgtcg acagcaccgc gagccccagc
     6301 gaaccaccca ccacctgtgt ggtgttgaac agcccggagg ccagtcccgc gtcctcctcg
     6361 cgcactcccg ccatcgccag ccccgtcagc gcgggcatcg cggcggcgaa cccgacggcc
     6421 agcagcagca tcggcggcag cacgtcggtg acgtacgagc cgtcgaccgg ggcccggctc
     6481 agcagcgcca gccccgcgac gatcagcgtg agtccggcca gcagcacccg gtacgcaccg
     6541 aaccggccga cggtccgggc cgagaacccc agcatcagca ccccgatcgc cacgggcgcc
     6601 ggcaggaacg ccgtgccggt ggccagctcg ccgtagccga gcacccgctg gaggtacagc
     6661 gcgccgatga actggaagcc gtacatggtc gccaccatca gcacctgcac ggcgttggcg
     6721 ccggtcagca gccgggagcg gaacagccgg agcctcagca gggggcgggc gacgcgtccc
     6781 tgccggacgg tgaaggcgac gaacagggcg agggcggagg cggccaggac ggccgtggtg
     6841 gaggtgccga gatcaccggc gccgacgatc gtgtacaccg tcagcatcag cgcgccggtg
     6901 accagggccg cgcccgggta gtcggcgccc cggacggagc ccgcggacgg gtccggagcg
     6961 aggacgcgga ccgccgcgag ccaggccaag acgccgatcg gcaggttgat caggaagatc
     7021 cagtgccagt tcagtgcctc ggtcagggct ccgccgagga aggtgccgag cgccccgccc
     7081 gccgcgccga ccgcgctgaa cacggcgatc gcccgggccc gttcccgcgg ttcggggaag
     7141 agcccgacca ccatgccgag caccaccgcc atggtcatcg ccccgccgag gccctggagg
     7201 gcccgcgccg cgatcagcag cccctggccg gtggcgaccc cgcacagcac ggacgccacg
     7261 gtgaacagcg cgagcccggt ggtgaacatc cgcttgcggc ccaccaggtc gcccagccgc
     7321 ccggccagca gcagcaggcc gccgaacggg atcaggtagg cgttgaccac ccaggcgagt
     7381 cccggcccgc tgaagccgag gtcggcctgg atcgcgggca tggcgacggt gacgatgttg
     7441 ccgtccagga tcgtcatcag cgctcccgcg cacaggacga cgagggcccg ccaccgcgag
     7501 ggtgctccca cctgcgtccg ggccggggac tcgatcatgg tcgtcatggc gacggggcct
     7561 ccgcttgtcg tggttcccag gtgcacttct tgtgacgggg accatcgtgg gtaaccctgg
     7621 aggccggcat aaggaggcag ttcgatgtcc cagaggaaca ccggtgttac gtcccaggca
     7681 gtcaacgcgc acgcgtgccc ggtccgcgag gttcttgaca gggtggcggg caagtggagc
     7741 gtccagatcc tggtggccgc cgcccccggc cccatccgct tcaccgaact ggagcgcagc
     7801 atcgagggcg tcagccgccg catgctgacg ctgaccctgc gcaacctgga gcgcgacgga
     7861 ctcgtcgtcc gcaccgtcca tccgaccgta ccgcccaagg tcgagtacga actcacggat
     7921 gtggcacagg agttgtacag ctcgctgcgg cacctgacgg actgggccga gcgcaaccgc
     7981 gtctacatcg ccgaggcgcg tgcggcctat gacaccgagc accggccgga gctggtggac
     8041 gcctgagggc ggcggcgggt cacaggccga acagccccgg ctccgaggcc agttccccga
     8101 agcgccgccg cggatcggcc accagcttgc gggcggtcag gtccatgagc ccgccgacgg
     8161 cctcgatctc cgcggcgacg gtgccgtccg ccttgcggac gacctgcacg atccggaagg
     8221 tcctgccctc gccccactcg aagacacagg acacctcgac ctcgtcgccc gcgagcagct
     8281 cccgccggta gcggatggtc gtctccagcg cgaccggacc cacgccccgc gcgaccaggt
     8341 cggcctgccg gatgccggcc gcgcggagca gcgaccagcg ggcgtgctcg gcgtagttca
     8401 ggtacacggc ctggttcacg tgtccctggg tgtcggtctc gtacccgcgg acggtcacgg
     8461 ggacggagaa cggttcgctc acggaagtcg cctctctcgt accggtacgg cgcgcgccga
     8521 tccgtcgatc ctgacacgtc cgtcgatcct gacacgggga gcctcacacc ttccgcggtg
     8581 aggccagcag gtagcgctcc cgcgtccgcg gctcggtgtg ctccccgacc tgccagcccg
     8641 cctcctccag cgccgtcgca cagccccgca gcgccgacgg gtcgggctcg tgcacggcga
     8701 cggcctcggg ctgcggtgtc gcccgcaccc ggtacccgcc gccaccgccc ggccccgccg
     8761 gacgcaggcc cgccgcctcc agggcgagcg cggccgcctg gaccagatgc gcacgctccc
     8821 acgcgcaggg ccggtccctg ctcccgtcgg agtgcgtcat ccggcgcagc tccaacagcc
     8881 cctgccaggc gccgcgcacc tcgcgcagcc gggccggacc ggcatcgccc gccgcggtct
     8941 cctcgccacc cacccgcgcg gcgaacaccc cgcccgcggc cggtgcggcc ggctcagggg
     9001 ccggggcctc gccggggccg gccggcgcct cccgtatccg gtgcccggcg ggggtgagga
     9061 agtggtcgtg cggcgggcgc gggtgccgga aggccagccc tcgcttcacc agggccgcga
     9121 gctgcgcccg cgtcccccgc aggcgcccgg tcacggggtc ggcggcgtcg atgacccgcc
     9181 gctgcgcggc ggtgggcgac agggccacgg cgtcctcctt ccgtcaccgg tgacgccttc
     9241 gaagactacg acggaggtct gacattccag gcggcgacca ccggccgccc gtgctccgtg
     9301 cccagtcggc acagcgtgcc cgtgccgagc tggaacagcg cgccgtggga cggctcgagc
     9361 cccaggtgcc gcgcggtcag tacgcgcagg aagtgcccgt gcgccaccag caccacgcac
     9421 ccctcggtgt cggcgaacgc ggcctccacc cgggccagca cccggtcggc ccgctcgccc
     9481 acctgttcgg gcgtctcccc gggacggtcc gcgggccccg gcgcgacacc gtccgtgaac
     9541 aggaaccagt ccggccggct gcggtggatc tcgaccgtcg tgatcccctc gtacccgccg
     9601 tagtcccact cgtgcaggtc cggatcgacc cgcaccccgt gcagcccgat cagctcggcc
     9661 gtctcccggg cccgctggaa ggggctgacg aacgcggccc cgatccggtg ggagcggatc
     9721 aacggcacca ggctccgcgc ctgctcccgc ccctgttcgg tcagtggaac gtccgtcagc
     9781 ccggtgtgcc gcccggaacg cgaccactcg gtctcaccgt gccggacgag aaagagatca
     9841 cccatgcgtc ccaggctatg cgcccccgcc gggcgtcgct cactgccggt acccgcccag
     9901 gaagcggccg atccggccga tggcggcctc caggtcgtcc gcgtggggca gggtgaggat
     9961 gcggaagtgg tcggtgcccg gccagttgaa gccggtgccc tggaccacct ggatcttctc
    10021 gcgcagcagc aggtccagga cgaaccgctc gtcgtcgtgg atcgggtgca ccttgggatc
    10081 gatgcgcggg aaggcgtaca gcgccccctt gggcttcacg caggagacgc ccgggatctc
    10141 gttcagcttc tcccaggcga cgtcgcgctg ctcgcgcagc ctgccgcccg gcgcggtcag
    10201 ctcgcggatg gactgccggc cgccgagcgc ggcctggatg gcgtactgcg cgggcgcgtt
    10261 ggcgcacagg cgcatggagg ccagcatggt caggccctcg aggtagtcgc gtgcgtgctg
    10321 ccgcggcccg gtgaccacca gccagccgga acggaagccc gccacccggt aggtcttcga
    10381 caggccgcag aaggtcagga cgaccaggtc gggggcgagg gcggcggccg agtggtggac
    10441 ggcgtcgtcg tacaggatct ggtcgtagat ctcgtcggcg aacaccatca ggccgtgccg
    10501 gcgggcgagg tcgaggatgc cctcgacgat ctccttgggg tagacggccc cggtggggtt
    10561 gttcgggttg atgaggacga ccgccttcgt gcggtcggtg atcttggact ccatgtccgc
    10621 gaggtccggg taccactccg cctgttcgtc gcacaggtag tgcacggcct tgccgcccgc
    10681 gagggtggtc accgccgtcc agagggggaa gtcgggggcg gggatcagta cctcgtcgcc
    10741 gtcctccagc agggcctgga cggccatgga gacgagctcg gagacgccgt tgccgaggaa
    10801 gacgtcgtcg acgccgacct ccaggccgag ggcctggtag cgctgggcga cggcccggcg
    10861 ggcggagagg acgccccgcg agtcggtgta gccgtgcgcc tgcgggagca tgcggatcat
    10921 gtcctggacg atctcctccg gcgcctcgaa accgaagagc gcggggttgc cggtgttcag
    10981 gcgcagcacg ctgtgccccg cctcctccag cgcgttggcc tgctcgatga ccgggccgcg
    11041 gatctcgtaa cagacctcgc tgagcttgtt cgactgccgg aactccatgc ggcgcttccc
    11101 ctccggtgac tggtgttgct tggttttacc aagtaggagc ttggaaagtc caacaacttg
    11161 tctacactgc gtcgcatgcc acctcgccga agctacgacc agtactgttc cgccgcccgc
    11221 gcgctcgacg ccgtcggcga ccgctggacc ctgctgatcg tccgggagct cctcgccggt
    11281 ccgcggcgct acaccgacct gcacgccgac ctgcccggcg tcagcacgga cgtactcgcc
    11341 tcgcggctca gggagatgga gcagggcggg ctggcgaccc ggcggcggct gcccccgccg
    11401 ggagcggcgt acgtctacga actgaccccg cgcggaagcg gattgctgcc ggtgctggag
    11461 gcgctcggcg cgtggggcgc cggcgagctg ggcgagcggc gccccacgga cgccgtgcgg
    11521 gcgcactggt tcgcgctgcc gctgcggcgc gccctgcggg aggcgggggc cggcgaggag
    11581 gtcgtcgagg tcgggctcga cgagggggag ttccacctgt acgcggggac ggacggacag
    11641 gggccggtgt acggcgacgg gcccgcaccc caaggggccg gtgcccggat cgtgttggac
    11701 gccctgacct gcgcggccct cggccgcggt gagctgagcc tgcgggacgc ggtgcgggac
    11761 ggccgggtcg aggtgaccgg cgagggcacg acggccaagg cgctccgcga gggctgacac
    11821 ggcggaaggc ccgccccggg ggcgggcctt ccgaaggcgt tcaggcggcc ggcggcaccc
    11881 gggacggccg gcccgagccg cgggtcagcg cgtatccgcc gacgcccgcg agcgcggcca
    11941 gtacgccccc gatcccggtc cacacccacc ggtcggacca ccagccggag gaccagccgt
    12001 cctcgggctc gatcgcggac agtacggcgc cgcggccggc gtcctcctcg tcggcgcccg
    12061 gccccacggc ggcgcccggc accagcggct cggccagcga accgtccacc gccgacgccc
    12121 cgcccatgtc cttggagtcc acctcgacct cggcacccac ccggacgccg aggtcggacg
    12181 tcggcaggtc cacgaccgtc agccggacgt agtacgtccc gggcagcggg tcgttcgccc
    12241 acggctccga ccaggcgcgc acggtgcgca gcacgcaggc gagctccacc gaaccggcgc
    12301 ccgccgccgc cgtacgggtc tgcgcgccgt actggcaggc ctggcggcgg cgcaggccgt
    12361 cgtagacgtc gacccgccag gtctcggcgg cgtgcgtctc gggcaggctc accgtggccc
    12421 gcacggtggg gcgctgtccg gcgtcggccg ggaacgacca gtacaggtag tcgcccgcgg
    12481 cgccgttcgc cgtggccggc cgtccctgct cgatctcggt cgccgtccgg aaggaggtgc
    12541 ccgccgtcgt cggcgcgccg ccgtcctccg ccgggctcgc ggtgggcgac gcatcggccg
    12601 ccgcggggcc ggcggtgatg cccagcagca gcaccgccac cgtcaacgtc tctctgaaac
    12661 gcatcagttg gtcctccaga ccgcgaaccg ccagcgcgac agccagcccc acagcaggcc
    12721 ggcgaggaag ccggcgagca ccagcacgcc gagcagccac cagccgcgtc cgaggccgaa
    12781 ggaggccacg tcgtcggcgt cgcccggtcc ttccacgacg tcgacggtca gctccagcgg
    12841 cagcccgggc gtgctcttca cgtcctcggc ggcggagaag gagtgggtga cctggagaca
    12901 cacggtctcc gcggccggct tgtccgcgtc cgcgtcgtcg cggtcggcct tcggatagcg
    12961 cagccccgcg gagatcacgt ccgtacggcc ctcgcccgcg gcctcaccgc ggacgatctc
    13021 ccggccgtgc accgtgaccg cccgcagcag cacgccgtag gacgggttca cggcacggtc
    13081 ggcgcccacg ctcaccgagg cgcgcaactc ctgcccgggc agcacgtcca cccggtacca
    13141 gcgctgctgc ccgaactcct cgcggtcggt gtacagaccc gactccagcg tcggcgcctt
    13201 cgtgcagacg tcggcgccct cggtggcgac cggcgtcacc accgggtcgg ccgcgcggtc
    13261 caccaactgg ttcacgcgat cggtgagttc gtcggtgtgc tcgatggagg tgtacgtccc
    13321 gccggtcgcc tcggcgatgc agctgagctg ctgccgcatc gtggcgttgg ggaccaggcc
    13381 cagcgtgtcg atggtcagcc cgatgccctt ggcggcgatc tcgcgggcca cctcgcacgg
    13441 gtcgagcggg gcgcaggtgt cctcgccgtc gctgatcagc acgatgcgct tggaaccgtc
    13501 accgccgtcg aggtcgtcgg ccgccgccag cagcgcggga ccgatcggcg tccagccggt
    13561 gggcgccagc gtggccaccg ccgtcttggc ctcggtacgg tccagcggtc cgaccgggta
    13621 gagccgcgcg gtgtccttgc agccggtcct gcggtcgtcg ccccgatagt cggcgcccag
    13681 ggtccggatg cccaaccgga cctcctcggg cgtcgcgtcg agcacctcgt tgaacgcctg
    13741 cttcgccgcg gccatccgcg tgccgccgtc gatgtcccgc gtccgcatcg aaccgctgac
    13801 gtcgagcacc aggtcgacct tcggcgcgtc ctcgccggcg ggttcaccgg cggccgcccc
    13861 ggccgggagg gcgatcccgg ccgccagcgc ggcgaccagg gcacaggcac ccgccgccag
    13921 ccgtgttctt gtgatcatcg gcggatctta ttgatcaatg gtctcgggct ccaaaacgag
    13981 accgcgcgta cgtcccggct tcacttccag tgcagcggat tgggcagccg cgcccactgg
    14041 tccccgctgc cgccgggcga agtgcgcatc agcgtcagcg ccttgaccgg cagcggtgcc
    14101 tcgcacaggg ccacgacgtc cggcgtacgg ggcagttcgc gcacggccgc ccccagggcg
    14161 tcccgcaacg ccgcacccga gcccgcgacc gacgccagcg cgccccccac cagcgacccg
    14221 aacaacttgc ggcgcagggc gtccgggtcg tccgtgagca tgcgggaggg cagttcgggt
    14281 gtccggacgc cgtggcgggc caggcgggcc ggcgagaccc ggatgtcggc caggtcgcgg
    14341 tagaccaggc gcagcggttc gcccgtcgcg gacagcaccg cgaggaggtt ctggccgtgc
    14401 gcctccagag ccacacccag ctccagcgcg cgcaggccca cgacgagcgc gagacgggcc
    14461 agggcggccg tccaccgcgg cgagcggggc agtccggtgg tcgccagcgc cgccaccggg
    14521 acgacgtgct cacccgcggc cgcgtggtcc cgcggcgact cgcgcagtac ggcggccagg
    14581 tcgggggagt gggcggtggc cgcgcccagt gtgcgggtca cgtggagcag gccgtccatg
    14641 cgcgccgcca gctcctcacc gaacgacgac agggtcgccg acgcggcgac ggaggcgacc
    14701 gagatgtccc gcaccgagga cgtcagccgg gcgctcagcg cggtcttgac gtgcggtccg
    14761 ccgggcacgg cgagcgtacg cagggacatg agcggatgcg cggcgagccg tccctcgcac
    14821 gggcgccgca gcacgtgcgc ggcctgccac gggtgcaccg gcagcaagag ccgcgagccg
    14881 tcccgcagct cccgcggcca cgcccccgtc accaggcatc ccgtcgccgg taccggcacc
    14941 aggccgagcc ccaccacggg cccgtgctcg ggcccgtacg ccagctgctc ggccaccgag
    15001 aagccgggcc gggaacggca gttggggtgg tagggatgcc cgtccaccac ccgctgctcc
    15061 caggcccagt cgctccgggg ccactcgtcc gggtgatcct cccggcccgc gtacgacagc
    15121 gccagcgacg cggcactgtg cccgagttcg gcggcgaacc ccgcggcgtg cggtacgccg
    15181 agctcggtca tcagccgcgc cggatcgtcg tacgcgaccc cgtccagccg cacgacgcgt
    15241 acgtacgggc ccgtgcggta cggatccgcc gccgggccgg tcagccgtcg gccgtcccga
    15301 aggcgcagga cgagttcctc cccggccggc tcccggtccg cgatccacgg catcggctcg
    15361 tgggcgaacg cacgccagag ccgggagagc accgccgcgc gggcgccggg cagctcggcc
    15421 gcgaaccggg ccacgagatc ggggcggacg gacgccagct cgtcggcgac ctcggcctcg
    15481 gcgacggggg gacggtgcac gggcggactc ctcgggtagg gacgggacgg cacggctcgg
    15541 gaacgacgac agacatactg atcgtctccg ccctctgaca gaccgtaggg aacgagtgga
    15601 acgcgtggat ttcctgcccc cgcccgccgg cgccgacgcc gcactccggg acgacgtcgc
    15661 cgaacgcgcc gacgcctacg ccgcggtacc gctgctgaac tgtctgctgc gcgaagtggc
    15721 cgaaccgctt ccggacaccg gcgcccggcc ggtgtaccgg ctccccggcg gcagactgct
    15781 gcgggtgcgc gcgggccggc ggcccgccga gccggaggtg tacgcggcgg gcggatggca
    15841 tcgcgccggc cacaccgaac tggtgaaact cgtcgcggag gaactgcgcc ggcacaccgg
    15901 gctgcccaac cacgaactgc ccaccgagat gaccgacagc cgcgacgcgg tggcggcgct
    15961 gctgacggcc cgtgcgcggg cgaccccgcc ggacgacccg tacgtccgct ccgagcagtc
    16021 cctgctcacc ggtcacaccc accaccccgc ccccaaggcg cgcggcggcg gcccgcacgc
    16081 cgactggctc ccgtacgcgc ccgagacgca cgcccgcttc ccgctggcgc tgctggccgt
    16141 gcgcgaggac acggtcgtcg acgagggcga caccaccgcc ctggacgccc tcggcgaagc
    16201 cccgcccggc taccggatgc tgcccgccca cccctggcag ctccggctgg cctcggccgc
    16261 cctggccccg gccttcgccg acgggcggat cgtccggctc ggcaccaccg gcttccccgt
    16321 ctggccgacg gccgcggtcc gcacggtgta cgcccccgag taccttccgg ggcgcgacct
    16381 gttcctcaag ttcagcctcg acgtccgcat caccaacgac atccggcgcc tgtggcgtca
    16441 cgacctgctg aggctgcgcc gcaccgacac ggcggtcagc gaggccttcg acgtcatcgg
    16501 ccccccggcg gcctggctcg ccgaccgcgg gcaccgcacc acggacttcg ccttcgagga
    16561 actggccgtc gtcgtgcgcg acggactgcg cggccgcgtc ctgcccggcg cgaccccgct
    16621 gctcgccgcc gcgctggtcg aaggcttccc gggcaacccg ctggagcgca ccgcggaccc
    16681 ggcggcctgg tgggaggcgt acctggccgc cgtcgtcccg cccgtgctga ccgccttcgc
    16741 cgacgacggg gtggtcctgg aggcacacct gcagaacaca ctggtcgcgg tggacgcggc
    16801 cgggacaccg gcgcaggccc tgttccggga cgccgagggc gtgaagctgc tgccggagac
    16861 ctcccgggcg gccggctggg aacggctggt ctactgcctg gtcgtcaacc acctctgcga
    16921 gatcgccggt gccctggccg agcaccaccc gggcctcgac ccctggcccg ccgcgcgccg
    16981 cgccctggcc cggcacgacc tgcccgagat ccccgccctc ctcgcctcgc ccaccctccc
    17041 cggcaagacc aacctcctgc tccgctggac gggcgcggac ggcgccgacg cccgctaccg
    17101 gccgctgccc aatccactgc gggagccgtg agggtccgcg cccccggccg cgcctcgggg
    17161 accgctcgtc ggtctgtcac gcttggtcac tatgctcagg tgatgccgga gaccaggggc
    17221 aggaagtgcg cagatccgga cgggccgacg tgggagacgg gatgctgagg agtgtcagcg
    17281 cgacacgcta tgtcacgccc ctgcactcgg gcggctccgt ccccggtgtc gtcgaggcgg
    17341 acgacctggg gacctacgtc gtcaagttca ccggttccgc acagggccgc aaggcgctgg
    17401 tggccgaggt gatcgtcggg gagctggccc gtgagctggg gcttcgggtg cccgagctgg
    17461 tcctcgccca cttcgacccc gggatcgccg ccgacgagcc gcaccaggag gtgcgggacc
    17521 tgctggacgc gagcgcgggg ctcaacctcg gcatggacta cctgtcgggc ggcgccgacc
    17581 tgacgccgga gctggcgcag gacttctccg tcggctccgg ggaagccggc cgcgtcgtct
    17641 ggctggacgc cctcaccgtg aacgtcgacc ggaccgtgca cagctccaac ctcatggtct
    17701 ggcccaccct cggcgtcgcg cccgcgcgcc tgtggctcat cgaccacggc gcggccctgg
    17761 tcttccacca ccgctgggac gcctccgcgc cggagaaggc ctacgacttc cgccaccacg
    17821 ccctgggccg gtacgcgccg gacgtccggt cggccgacgc cgagctggcg ccgaaggtga
    17881 cggaggaact gctgcgcgag gtggtggcgc gggtgccgga cgactggctg acctgcgagg
    17941 ccggcttcga caccccgggg gaggtcaggg acgcctacgt gggctacctg tccgcgcggg
    18001 tgcgcgcctc gcgcgactgg ctgcccaccg acttcccgtc ccgcgaggag ctcgccgccg
    18061 agaacgccgc ccgcgcggcc cgtacgcggc gcgggcgccc cgactggctc aagcgcgtcc
    18121 ccgacctgca cggcaagccc tccgccgcgc cggactggtc ccggcacctg tcctgaacac
    18181 aggcccgcgc ccccggtgcc gtgcggtacc gggggcgcgg gcctgtccgt gagcggcgcc
    18241 ggcgtcagcc cttcagctgc tcgtaggcgg gcagcgtcag gaagtcggcg tagtcctcgt
    18301 cgagcgacac cgtgagcagc aggtcgtggg cctgctgcca gttgccggcc gcgaaggcct
    18361 cgtcgccgat ctcggcgcgg acgttcgcca gctcctcggc ggcgaccttg cgggccagct
    18421 cggcggtgac ctgctcgccg ttgtcgagga cgacctccgc gttgatccac tgccagatct
    18481 gcgagcgcga gatctcggcg gtggccgcgt cctccatcag attgaagatg gcgaccgcgc
    18541 cgaggccgcg cagccacgcc tcgatgtaac ggatgccgac ctggacggcg ttgaccagac
    18601 ccgcgtaggt cggcttggcg tccagcgagt cgatcgcgat caggtcggcc gcccgcacgt
    18661 cgacgtcctc gcgcagccgg tccttctggt ggggcttgtc gccgaggacc ttgtcgaagg
    18721 actccatggc gatcgggacc aggtcggggt gggcgaccca ggagccgtcg aacccgtcgt
    18781 tcgcctcgcg gtccttgtcg gcgcggacct tctcgaaggc gaccttgttg acctcggcgt
    18841 cgcgccgcga ggggatgaac gcggccatgc cgccgatcgc gtgcgccccg cgcttgtggc
    18901 aggtgcggac gaggagctcg gtgtacgcgc gcatgaacgg cgcggtcatc gtcacggcgt
    18961 tgcggtccgg cagcacgaac ctggcgccgc cgtcccggaa gttcttcacg atggagaaca
    19021 ggtagtccca gcggccggcg ttcagtccgg cggcgtggtc gcgcagttcg tagaggatct
    19081 cctccatctc gtacgcggcc gtgatcgtct cgatcaggac ggtggcgcgg acggtgccct
    19141 gcgggatgcc gacgtagtcc tgcgcgaaga cgaagacctc gttccagaga cgggcctcca
    19201 ggtgcgactc cgtcttcggg aggtagaagt acgggccctt gccgaggtcc agcaggcgct
    19261 gggcgttgtg gaagaagtac aggccgaagt cgaccagcgc gcccgggacc gcgcggccgt
    19321 cgacctggag gtgacgctcg tcgaggtgcc agccgcgcgg gcgcatgacg accgtcgcca
    19381 gctcctcgtc cgggcgcagg gcgtacgact tgccggtgcg ctcgtcggtg aagtcgatgg
    19441 tgcgggtgta ggcggcggtc aggttgagct ggccgaggac cacgttctcc caggtcggag
    19501 cggaggcgtc ctcgaagtcg gcgagccaga cccgcgcacc cgagttgagc gcgttgatgg
    19561 tcatcttgcg gtcggtcggg ccggtgatct cgacccggcg gtcctgcagc gcggccgggg
    19621 ccggggccac cttccaggag tcgtccgcgc ggacggcggc ggtctccggg aggaagtcga
    19681 gcgtggaggt gcgggcgatc tcggcgcggc gctccgcacg gcgggtgagg agctcgtcac
    19741 gccggggcgt gaacctccgg tgcagctcgg ccacgaaggc gagcgccgca tcggtgagga
    19801 cctcctcctg ccggggcaga ggctcggcgt cgacgatggc cagcgtggac ggcgctggtg
    19861 cggacatgag ctgtcacttc cttcagcggt ggcaccgggt gccagagggc gcgtacgggg
    19921 cattgcgcac tcgcagtggg ggtccccccg gtcgagcgca gccgagagtg gggaggacga
    19981 gtgcttctgg tcagtggata gtagtttcct catcgtggaa cttcaaggag tgttgatgtc
    20041 gagattctct gagtcgaggg aaggtggcgc ccagtgccac gccactcact cgaggtggtg
    20101 caggtcggcc gcggtgtcga tgtcgtaggg cagcgccacg tccccgcact ccacgagcgc
    20161 gatctccgcc tcgtgttccc tcagataggc gcgtgccccc cggtccccgg tcgcagtcgc
    20221 cgagacgccc gcccagtggg cggcgccgag caggacggga tgcccgcgca cgcccgcgta
    20281 cgccgccgag gcgagcgacg tctcgtcccg gtacccggcg cgcacccgtg ccatcgcccg
    20341 cgcgccgatg ccgggctggt ccaccagcga caccagcgcg gcccgcgctc cggtgccggc
    20401 cagtgagccg agcccggcgc acagcgacga gcccatgccc tcttcccagg cggggttgtc
    20461 caccagtacg catccgtcga gcgccgcccg cgcccgcacc tcctcggcgc gcgcccccag
    20521 gacgacgtgc acgcgggtgc agcctgccgc gcgcaacgcg gcgatcgcat gttcgacgag
    20581 cgggtgtccg tggtgttcga gcagggcctt gggccgtccg ccgagccgcc gcccgccgcc
    20641 ggcggccagc agcaccccgg ccacctggtc ttcgttgtcc gtcatgcgtc ctgcataccc
    20701 gaccgcccgt cgaacgcccc ggcgcgcggc gggcttatca gaggactgaa tttcggtccg
    20761 cccggtggcg cgtccggcgc caggtggcgt ttactggccc gcgtccccgg cgcccgacca
    20821 gcgacctggg gcgctcggca cgttcaccag gcaggggcgc acgacggcgt gcgaggggga
    20881 ggggctgtgt tgcggagctt ggggcagggg caggtgacgg tcggcgacga ggacgtcagg
    20941 gtgacggcgc tgcggaccgc ggtgtcccgg ttgcgccgtc aactcgcgtt gctgcgcgcg
    21001 gacttcccgg accgggccgt ggccgaggac gaactggcgg acctggccgc gatgacggcg
    21061 cacggggtcc ccgaggtgtc ccggctgcac cgctccctgc tgctgatagt cggggcgatc
    21121 ggctccgtca gcgccttgtc gcgaggcctg acggaggtcc gtcaggccgt cgagctcttc
    21181 ggcgaccccc cgcgtcggtg agccacgggc cgacgcgttc gccggccacc ccgcgcggcg
    21241 gtgccccgcg ggccggcgtg cccgcctgtc gggcgtcggc tcggggcggc ccggagcggg
    21301 cgtgagcggt gcgtctcgcc gcgccggtgg cggcagccgt cgtgcggggc ggtgacgacc
    21361 ggaagccctc cgtgcgagcg gtggccgctc aggcggccgg ggtgccgttc gaggccagca
    21421 gggcctccga cagttcggcc gcgacctgct ggagcagcgg caccatccgg tcggtggcgg
    21481 cctccgtgac ccggccggcc gggccggaga tggagatggc ggccgcggtg ggggagttcg
    21541 gcaccgagac ggccaggcag cggacgccga tctcctgctc gttgtcgtcg atcgcgtagc
    21601 cctggcgccg cacgtccgcc agcgccgcga tgaaaccgtc cggtgtggtg atggtcttct
    21661 cggtcgcggc cggcatgccg gtccggccca gcagcgcccg cacctcgtcc gccgggaagt
    21721 ccgcgagcag cgccttgccc actccggtgg agtgcggcag cacgcgccgg ccgacctccg
    21781 tgaacatgcg catcgagtgc ttggacggca cctgggcgac gtacacgatc tcgtccccgt
    21841 ccagcagtgc catgttcgcc gtctcaccgg tctcctcgac cagccgggcc aggtgcgggc
    21901 gggcccaggt gccgagcagc cgggaggcgg actcgccgag ccggatcaga cgggggccca
    21961 gcgcgtaccg gcggttgggc tgctggcgta cgtacccgca ggccacgagc gtgcgcatca
    22021 ggcggtggat ggtgggcagc ggcagtccgc tgctcgcgga gagctcgctc aggccgacct
    22081 cgccgcccgc gtccgccatc cgttcgagca ggtcgaaggc gcgctccagg gactggacgc
    22141 cgcctgtggc ggacctggcg gagtcggtgg tgctggcgct ggacgtcggc acggcacgtt
    22201 cctttcgggg ctggcgggag gaaagaagcg tacccggcgg ccggttgact accggcttgt
    22261 acgtagctac gttctgcttg ctggaattct aattccgctt tgtggaaacg tccagggctc
    22321 ggtcgtggtc acgcctacac aaagggtgcc tcttgacggg gcggaaccgg gaatgaagac
    22381 tccttcaaca gaacgttgaa atcgtcggcg gagatcggcg gagagagggg ttcgggtgtc
    22441 cgaggctgaa ctggtgctgc gctcgacgcg cgtcgtcact cccgagggga cacgcgccgc
    22501 gtccatcgcg gtgaccgggg agaagatcac ggccgtcctg ccgtacgacg cccccgtccc
    22561 ggcgggcgcc cggctggagg acgtcggcga ccacgtcgtc ctgcccggcc tggtcgacac
    22621 ccacgtgcac gtgaacgacc ccggccgcac cgagtgggag ggcttctgga ccgccacccg
    22681 cgccgcggcg gccggtggca tcaccaccct cgtcgacatg ccgctcaact ccatcccgcc
    22741 gaccaccacg gtggagaacc tgcgcaccaa gcgcgaggtc gccgccgaca aggcgcacat
    22801 cgacgtcggc ttctggggcg gcgccctgcc cgacaacgtc aaggacctgc gcccgctgca
    22861 cgagtccggc gtcttcggct tcaaggcctt cctgtccccg tcgggcgtgg acgagttccc
    22921 gcacctggac caggagcaac tggcccggtc cctggcggag atcgccgctt tcgacggcct
    22981 gctgatcgtg cacgccgagg acccgcacca cctggccgcg gccccgcagc agggcggccc
    23041 caagtactcc cacttcctcg ccagccgccc gcgcgacgcc gaggacaccg cgatcgccgg
    23101 cctcctcgcc caggcgaaac ggctcggcgc gcgcgtgcac gtgctccacc tgtcctccag
    23161 cgacgccctg ccgctgatcg ccgaggcccg cgccgagggc gtgcgggtga cggtcgagac
    23221 ctgcccgcac tacctcaccc tcaccgccga ggaagtgccc gacggcgcca gcgagttcaa
    23281 gtgctgcccg ccgatccgcg aggccgccaa ccaggacctg ctgtggcagg cgctggtgga
    23341 cggcaccatc gactgcgtgg tcaccgacca ctcgccgtcc acggccgacc tcaagaccga
    23401 cgacttcgcc accgcctggg gcggcatcgc cggcctccag ctcagcctgc cggccatgtg
    23461 gaccaaggcc cgtgagcgcg gcctcggtct ggaggacatc gtgcgctgga tgtccgcgaa
    23521 caccgcaagc caggtggggc tcgacgggcg caagggcgcc atagccgccg gccacgacgc
    23581 cgacttcgcc gtcctcgccc ccgacgagac cttcaccgtc gacccggccg ccctccagca
    23641 ccgcaaccgc gtcaccgcgt acgcgggcaa gaccctgtac ggcgtcgtga agtccacctg
    23701 gctgcgcgga cggcgcgtcg tggcggacgg cgcgttcacc gagccgaagg gacagctcct
    23761 cgaccgggcc tgacgcgtcc ggaccccttg aaccacacac accacgaacg accccgaaag
    23821 gaacacctga tcaccgtgac ggcccagcag aacccctcgt tggccagctt caccggagac
    23881 gcgaacccct acggaggcgg cgacccgtac gcggactacc gcaccgccga cctccccttc
    23941 acccagtacg ccaaccttgc cgaccggcag ctcggcgcgg gtgtcgtcgc cgccaacgac
    24001 gagttcttcg cccagcgcga gaacctgctg gtgccggagc ccgccgagtt cgaccccgag
    24061 cacttcgggc acaagggcaa ggtcatggac ggctgggaga cccgtcggcg ccgcggcgcg
    24121 tcggccgagc acccctggcc caccgaggac gaccacgact gggcgctcat ccgcctcggc
    24181 gcccccggcg tgatccgcgg catcgtcgtc gacacggccc acttccgcgg caactacccg
    24241 caggccgtct ccgtcgaggg cacctcggtc gcgggctccc cgtcgcccga ggaactgctc
    24301 gcggacgacg tcaagtggac gaccctggtc ccgcgcacgg cggtcggcgg ccacgcggcc
    24361 aacggcttcg ccgtcctggc cgagcagcgc ttcacccacc tgcgcctcaa gcagcacccg
    24421 gacggtggta tcgcccgcct gcgggtgtac ggcgaggtcg tccccgaccc cgcgtggctc
    24481 acggccctcg gcaccttcga cgtggtggcg ctggagaacg gcggccaggt cgaggacgcc
    24541 tccaacctct tctactcgcc ggccaccaac accatccagc cgggccgctc ccgcaagatg
    24601 gacgacggct gggagacccg ccgccgacgg gaccagggca acgactggat ccgctaccgg
    24661 ctggtggacc gctcgcagat ccgcgcggtc gagatcgaca cggcctacct gaagggcaac
    24721 tcggccggct gggcgtcggt gtccgtgaag gacggtgagg acggcgagtg gcgcgagatc
    24781 ctgccgcgca cccggatgca gcccgacacc aaccaccgct tcgtgctgcc ggagacggcc
    24841 gtcggcaccc acgcgcgcgt ggacatcttc cccgacggcg gcatctcccg cctgcgcctg
    24901 ttcggttccc tgaccgagga cggcgcggcc cacctcgccg cccgccacca ggagctcggc
    24961 ggctgaccca ccccgacccg tggggcgcgc ccggcctgga cagcaccggc gcgccccacg
    25021 cgcatccccc cgtcggtgtc aggccgcgtg gccgccgtcc accgagaact ccgccccggt
    25081 gacgtacccg gccgtcgcca ggtgggcgac ggtcgacgcc acctcctcgg ccgtgccgaa
    25141 gcggcccagc gcggtcagcg ccgcctgccc ctcggcgtac ggtccgccgg ccgggttcat
    25201 gtcggtgtcg atcggcccgg ggtggacgat gttcgcggtg atgccccgcc cgcccagctc
    25261 ccgggccagg gccttggtca gcccgatgag cgccgacttg ctcatcgcgt acagcgtccc
    25321 gccgggaccc ggcacgcgct gcgccatgca gctgccgacg gtgatgatcc gcccgcccgc
    25381 ggtcatccgg gcggccgcgg cctgagcggt gaggaagacg ccccggacgt tgacggccag
    25441 cacccggtcc aggtcgccca ccgagaagcc ctcgacgggg ccgagcagcc cgacacccgc
    25501 gttgttgacc agcacgtcga gcccgcccag ggcgtccgcg gcccgctcca ccgcccccgc
    25561 ggcctcgtcc gcgtcaccgg cgtccgcccg cagggccacc gcccggcgcc ccagcgcctc
    25621 cacggcccgt acgacgtcct cggccgcctc cttgccgttc acataggtga gggccacgtc
    25681 cgcgccctcc cgggccagcc gcagcacggt cgccgcgccg atgccgcggc tgccgcccgt
    25741 cacgagggcc gtccggccgg tcagcggcgg gagcgtggga tgagtgagtg tgttcgtgtt
    25801 catgcctcca tcccagcgga ccgggacggc tcgtaccggc ggtgaacgga cgtcgtcctc
    25861 gcgcggacga cgcgccgaac tcgccgaaag tacatacgac ttaccggcaa cctccacggt
    25921 cttgtcattg acatgccact gtctacgcgc gtcatcatga cgtcatgcga ttccccccac
    25981 gcgccgcccg gctcggcgcg gcagccgcag tcctgtccgc cctcctcgtg ggcggcaccg
    26041 tctcggcgac caccgcggga gccgcccccg ccgcggtcgg cgacatctgc ctcagcgacc
    26101 tgccctcgca ggcgcacgac accctcgacc tgatcgaaca gggcggcccc taccccttcg
    26161 aacaggacgg gaccgtcttc cagaaccggg agggcatcct gcccgaccgg tccaccggct
    26221 actaccacga gtacacggtg atcacccccg gctccgacac ccggggcgcc cgccggatcg
    26281 tcaccggtga gcagacccgg gaggactact acacggccga ccactacgcc tcgttcgacc
    26341 tcgtcgacca cggctgctga gaaccgcggc ccgggcccgg cccggacccg gggtcacccg
    26401 cgccggctct cggcggcggc gaacagcgcg ccgccgagag ccagcagcac cacgctcgcg
    26461 tagacctcgt agccgtcgag gacgccgatc cgctgcacca cgccccagtt ccagtcggtg
    26521 aactcgtgca ccagaccggc cacgccttgg atcacggcca tcaggcccag gaactccagc
    26581 aactccttca tgccgacgac cctcgccccg cggtcccccc acacgcatcg gccgcggggc
    26641 gagccctgcc cgacggaagg ctccggtgcg cgcgggcccg ggcatcgaaa gtcgacggct
    26701 tcgcgacttc ggtcgctcat cccgctctcc cggccgccgt ggccgccacc gctgcgtaga
    26761 ttcgtcgacc gtgaacagtg acaagcaggc cacgacaccc cccgcgttcg ccaagcggcg
    26821 ctgggtgctg ccggcggcgc tggtcgagga catgtatccg cagtcgcggc gggccgacgg
    26881 acgaccgcga cgcaccgggc gcgactggat cgtcgacttc acctgcttcc tgctcgcggt
    26941 cggcgtcggt ctgctggccg ccgacacgct cgaccaggag ccgaacctgc cgcggagcat
    27001 ggagctggcc gaccaggtgg tcggagcgct ggcctgtgcc gcggtctggc tgcggcgccg
    27061 gtggccggtc gggctggccg tggcgatggt gcccgtctcc atggtctcgg ccacctcggg
    27121 cggcgccgcg ctcctttccc tcttcacgct cgccgtgcac cgtcccttcc gctacaccgc
    27181 ctggatcggt ggcgcgagcc tcgccctgat gcccctgtac ttctggatgc ggccggaacc
    27241 cgacctgccg ttcctggcgt cgctcgtcat cgcctccctg ctcgccgtcg cgatcgtcgg
    27301 ctggggactg ctcgtccgct ccaagcgcca gctcctgctc agcctgcgcg accgtgcccg
    27361 gcgcgccgag aacgaggcgc ggctgcgcgc ggagcaggcg caacgactgg cccgggaggc
    27421 catcgcacgc gagatgcacg acgtcctggc acaccggctg acgctgctca gcgtgcacgc
    27481 gggcgcgctg gagttccggc ccgacgcctc ccgggaggag gtggcgcggg cggccggtgt
    27541 catccgcgag agctcgcacg aggccctcca ggacctgcgg gagatcatcg gtgtcctgcg
    27601 cgccggggag tccgacgacg cgggccgccc ccagccgacc ctcgccgccc tcgacgccct
    27661 ggtcgccgag tgccgggaag ccggcatgaa gatcaccctg gccggtcggg tcaccgaccc
    27721 cgccggtgta cccgcctccg tcggccgcac cgcctaccgc gtcgcccagg aggcgctgac
    27781 caacgcgcgc aagcacgccc ccggcaccga ggtcagcgtc tccgtcgccg gggccccggg
    27841 cgagggcctc tccctgtccg tgcgcaacgc cccgcccgtc ggcgaggtgc cccccgtgcc
    27901 cggttccggg cagggcctca tcgggctgac cgagcgcgcc acgctcgccg gcggcaccct
    27961 ggagcacggc cccacgtccg agggcggttt cgaggtacgg acacggctgc cgtggggctg
    28021 agaccgtccc gggcggcggt cgtcgaagga acggagtcgg ccggcggcaa ccgtgattac
    28081 gtatggccca tgactgcgat cagactgctc ctcgtcgacg acgacccgct cgtgcgggcc
    28141 gggctgtcct tcatgctggg cggcgccgac gacgtcgaga tcgtcggtga ggccgccgac
    28201 ggcgaccagg tcgaggcgct cgtcgaccgc acccggccgg acgtcgtcct catggacatc
    28261 cggatgccgg tggtggacgg cctgacggcg accgagcggc tgcgctcccg ccccgacgcc
    28321 ccgcagatcg tcgtgctcac caccttccac gccgacgagc aggtgctccg ggccctgcgc
    28381 gccggtgccg ccggcttcgt cctcaaggac accccgccgg cggagatcct cgacgcggtg
    28441 cgcagggtcg cggccggcga ccccgtcctg tcgcccgccg tgacccggcg gctgatggcg
    28501 cacgcggccg gcggcaccgc cgacaccagg cgcacccgcg cgcgtgcgcg cgtcaccgcc
    28561 ctcaacgacc gcgagcgcga ggtggccgtc gcggtcggcc gcggcatggc caacgccgcc
    28621 atcgccgcgg agctcttcat gagcgtcgcc accgtcaaga cccacgtctc ccgcatcctc
    28681 gccaagctcg acctggacaa ccgggtgcag atcgcgctgc tggcccacga cgcgggactc
    28741 ctggacgagt acggcgagga agcgcgctga cgccggatac cgacgcgccg tcggcggcgg
    28801 accacgagcc cacggcccgc ccgcctcacc accggcgccc acgccccgcc ggaacacgtc
    28861 ccgccgcgca ccgccgacgt ggccggtgcc cggccgacgg atggccggag cgccccccaa
    28921 aggccggcgg gtggccggcg ggtccgcccc actgggccgg cgggtggccg gcgggctgcc
    28981 cactgggtcg gcgggcctgc accgggccgg cgggcctgca ccgggccggc gggcctgcac
    29041 cgggccggcg ggcctgcact gggacgatgg gcctgcactg ggacggtggt ggtcggaggg
    29101 ccccgcccgc tcggccggcg ggtggtcgaa ggcccgccct caccccgtcg cggacgcccc
    29161 ggcgccgggg acctccgccg gccgtacggg tctgcgctcc cgccgggaga tctcgcaggc
    29221 ctcggcgatc agcagggccc gcagcgcctc gcgcccgtcg cacggattgg cccgctcgcc
    29281 gcgcacgacc tgaacgaagg cggccagctc cgcctcgtac gcgggtccga accgctccac
    29341 gaagccggtc cacggtttgt ccgcggcggg cggcccggtc ggctccgtcg aggcgatcgg
    29401 cgtacggtcg tcgaggccga cgacgatctg gtccagctcc ccggccagct ccatgcgcac
    29461 gtcgtacccc gccccgttca gccgcgtcgc ggtcaccgtg gccagcgtgc cgtcgtccag
    29521 cgtgagcagc gccgcgcccg tgtccacgtc gtcggccgcg cggaacatcg gcggcccggc
    29581 gtccgacccg gcggcgtaca cgtcggtgac ctcccgcccg gtcacccagc gcaggacgtc
    29641 gaagtcgtgg atgagcgtgt cccggtagag cccgccggac tgcggcaggt acgcggtggg
    29701 cggcggcgcc tggtcgctcg tcaccgcccg gacggtgtgc aggcggccca gccgtccgga
    29761 ccgcaccgcc tcgcgggccc ccgtgtaacc ggcgtcgaag cgccgctgga agcccatctg
    29821 gagaaccgtc ccggcggcct ccacctcggc gatcgcctgg agcgtgccgg gcacgtccag
    29881 cgcgatgggc ttctcgcaga acaccggcag ccccgagcgc gctgcccgac cgatcagttc
    29941 ggcgtgggcc gcggtggccg tggtgatcac cacggcgtcc acgccccacc ggaagatctc
    30001 gtccaccccg ggggcggccg tctcgccgag ccggtgggcc aggtcctggg cgcgcccgag
    30061 gtcggcgtcc gtgaggatca gggacccgac gtcgcgatgg cggctgagcg tgttggcgtg
    30121 aacggtgccg atgcggcccg taccgatgac cccgatgcgc atggaatcaa agtgggcgca
    30181 cagcgcacgc cctgtcaatg cgtatgtccg gacaatcgaa ctacacaact tcccgtcaac
    30241 agcgcacgga gctacgctcg ggccgtgccg aaaccagaag tggacccgac cgtgtcgctg
    30301 gacctcagcg tggatcgcag cagccccgtg ccgctgtact tccagctgtc gcagcagctg
    30361 gaggccgcga tcgagcacgg tgcgctgacc cccggcagcc tgctgggcaa cgagatcgag
    30421 ctcgccgcgc ggctcggcct gtcccggccc accgtccgcc aggccatcca gtcgctcgtc
    30481 gacaagggcc tgctcgtgcg ccgccggggc gtcggcaccc aggtcgtgca cagcaaggtc
    30541 aagcgcccgc tcgaactcag cagtctctac gacgacctgg aggccgcggg acagcgtccg
    30601 gccacgaagg tgctggtcaa caccgtcgtc cccgcgaccg cggaggtcgc cgccgcgctc
    30661 ggtgtggtcc aggagagcga cgtgcaccgg gtggagcggc tccggctggc gcacggggag
    30721 ccgatggcgt acctgtgcaa ccacctgccg cccggtctcg tcgatctgga caccggacag
    30781 ctggaggcca ccggcctgta ccggttgatg cgcgccgccg ggatcaccct gcacagcgcc
    30841 cgccagtcca tcggcgcccg ggccgccacc gccgacgagg ccgaacggct cggcgaggac
    30901 gtgggcgccc ccctgctcac catggaacgc acgacgttcg acgacacggg gcgcgcggtc
    30961 gagttcggca cgcacaccta ccgtccgtcc cgctactcct tcgagttcca gctgctcgtg
    31021 cggccctgac cggcgccgtc cggtggcggt ccccgccgtg cgggttcgtc tcaatgtccg
    31081 gacaatgtga ccgtcatcgc actccccgga ggcgagtgct ccgcttgcgt g
//
