LOCUS       NZ_CP010449            41176 bp    DNA     circular CON 21-JAN-2024
DEFINITION  Streptococcus pyogenes strain NGAS322 chromosome, complete genome.
ACCESSION   NZ_CP010449
VERSION     NZ_CP010449.1
KEYWORDS    RefSeq.
SOURCE      Streptococcus pyogenes
  ORGANISM  Streptococcus pyogenes
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1950469)
  AUTHORS   Fittipaldi,N.
  TITLE     Direct Submission
  JOURNAL   Submitted (05-JAN-2015) Public Health Ontario, 661 University Ave,
            Toronto, Ontario M5G 1M1, Canada
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Celera v. 7.0; Quiver
            Genome Coverage                   :: 114X
            Sequencing Technology             :: SMRT PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 01/21/2024 01:43:10
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 1,960
            CDSs (total)                      :: 1,871
            Genes (coding)                    :: 1,812
            CDSs (with protein)               :: 1,812
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 67
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 59
            CDSs (without protein)            :: 59
            Pseudo Genes (ambiguous residues) :: 0 of 59
            Pseudo Genes (frameshifted)       :: 29 of 59
            Pseudo Genes (incomplete)         :: 33 of 59
            Pseudo Genes (internal stop)      :: 21 of 59
            Pseudo Genes (multiple problems)  :: 20 of 59
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:43:16
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 688373
            Orig. end                         :: 729549
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP010449.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Source DNA available from Nahuel Fittipaldi,
            Nahuel.fittipaldi@oahpp.ca.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..41176
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="2"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41176
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41176
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21176](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21176)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            219..926
                     /locus_tag="SD89_RS03380"
                     /old_locus_tag="SD89_03375"
     CDS             219..926
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990206.1"
                     /locus_tag="SD89_RS03380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03375"
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="WP_002990206.1"
                     /transl_table=11
                     /translation="MTKKKGKLVLISLFVLAACLGAYSAMRQSHKTSNVSAETIASSST
                     RHFIDEIGPTASTIGQERDLYASVMIAQAILESSNGKSSLSQAPYYNFFGIKGAYNGSS
                     VTMSTWEDDGNGNTYTIDQAFRAYPSIADSLNDYADLLSSSTYIGARKSNTLSYQDATA
                     ALTGLYATDTSYNLKLNNIIATYGLTAYDVANSSAQETGLATSGYVWNEYRRNYTDAET
                     LAVDEAWAKRMTY"
     gene            complement(983..>1300)
                     /locus_tag="SD89_RS03385"
                     /old_locus_tag="SD89_03380"
                     /pseudo=""
     CDS             complement(983..>1300)
                     /GO_process="GO:0015074 - DNA integration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /locus_tag="SD89_RS03385"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="SD89_03380"
                     /product="IS3 family transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="KCYDGTI"
     gene            complement(1498..1863)
                     /locus_tag="SD89_RS09760"
     CDS             complement(1498..1863)
                     /GO_component="GO:0005576 - extracellular region [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014875.4"
                     /locus_tag="SD89_RS09760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="exotoxin beta-grasp domain-containing protein"
                     /protein_id="WP_153276780.1"
                     /transl_table=11
                     /translation="MPSTDDGILRTNTIAGNFFIDGQQQKTLINPIKIDKDIVTIQEFD
                     FKIRKFLMESKEIHLTKSPYIRGSLEIHSKNRKHEKIDLYDAKPNSTRSDVFKKYKDNK
                     TINMKDFSHFDIYLWTK"
     gene            complement(1883..2908)
                     /locus_tag="SD89_RS03395"
                     /old_locus_tag="SD89_03390"
     CDS             complement(1883..2908)
                     /EC_number="3.4.22.-"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635407.1"
                     /locus_tag="SD89_RS03395"
                     /note="This family includes IgM or IgG-cleaving cysteine
                     proteases.; This family includes IgM or IgG-cleaving
                     cysteine proteases.; This family includes IgM or
                     IgG-cleaving cysteine proteases; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="SD89_03390"
                     /product="IdeS/Mac family cysteine endopeptidase"
                     /protein_id="WP_053308297.1"
                     /transl_table=11
                     /translation="MRKRCYSTSAAVLAAVTLFALSVDRGVIADSFSANQEIIYSEVTP
                     YHVTSVWTKGVIPPANFTQGEDVFHAPYVANQGWYDITKTFNGKDDLLCGAATAGNMLH
                     WWFDQNNEKIEAYLKKHPDKQKIMFGDQELLDVRKVINTKGDQTNSELFNYFRDKAFPG
                     LSARRIGVMPDLVLDMFINGYYLNVYKTQTTDVNRTYQEKDRRGGIFDAVFTRGDQSKL
                     LTSRHDFKEKNLKEISDLIKKELTEGKALGLSHTYANVRINHVINLWGADFDSNGNLKA
                     IYVTDSDSNASIGMKKYFVGVNSSGKVAISAKEIKEDNIGAQVLGLFTLSTGQDSWNQT
                     N"
     gene            3411..3587
                     /locus_tag="SD89_RS03400"
                     /old_locus_tag="SD89_03395"
     CDS             3411..3587
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="SD89_RS03400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="SD89_03395"
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="WP_002985013.1"
                     /transl_table=11
                     /translation="MIKLYGFKYGLVGEVLRRIERLGFTFERLELRQASSKYLAKHDEA
                     LVINLFILDLKLT"
     gene            3815..4195
                     /locus_tag="SD89_RS03405"
                     /old_locus_tag="SD89_03400"
     CDS             3815..4195
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985011.1"
                     /locus_tag="SD89_RS03405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03400"
                     /product="DUF1149 family protein"
                     /protein_id="WP_002985011.1"
                     /transl_table=11
                     /translation="MQLVREKEFVNQYHYDARNLEWEKENGTPETNFEVTFQLIDKDEQ
                     QKETVIVSVLQFVIVKEEFVISGVISQMVRILDRLVDKPSEFTQEEVESLAAPLLDMVK
                     RLTYEVTEIALDRPGIHLEFKN"
     gene            4195..5043
                     /locus_tag="SD89_RS03410"
                     /old_locus_tag="SD89_03405"
     CDS             4195..5043
                     /GO_function="GO:0005504 - fatty acid binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985007.1"
                     /locus_tag="SD89_RS03410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03405"
                     /product="DegV family protein"
                     /protein_id="WP_002990194.1"
                     /transl_table=11
                     /translation="MKLAVITDSTATLPTDLKQDKAIFSLDIPVIIDDETYFEGRNLSI
                     DDFYQKMADSQNLPKTSQPSLSELDNLLGLLSSKGYTHVIGLFLAGGISGFWQNIQFLA
                     EEHPEIEMAFPDSKITSAPLGSMVKNVLDWSRQGMTFQAILNKLQEQIDGTTAFIMVDD
                     LNHLVKGGRLSNGSALLGNLLSIKPILRFDEEGKIVVYEKVRTEKKAMKRLVEILNDLI
                     ADGQYNVSIIHSKAQDKADYLKRLLQDSGYQYDIEEVHFGAVIATHLGEGAIAFGVTPR
                     L"
     gene            5168..6376
                     /locus_tag="SD89_RS03415"
                     /old_locus_tag="SD89_03410"
     CDS             5168..6376
                     /EC_number="2.7.7.72"
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001680 - tRNA 3'-terminal CCA addition
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880307.1"
                     /locus_tag="SD89_RS03415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03410"
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="WP_002990193.1"
                     /transl_table=11
                     /translation="MKLMTMPSEFQKALPILTKIKEAGYEAYFVGGSVRDVLLERPIHD
                     VDIATSSYPEETKAIFNRTVDVGIEHGTVLVLENGGEYEITTFRTEDVYVDYRRPSQVS
                     FVRSLEEDLKRRDFTVNALALDENGQVIDKFRGLIDLEQKRLRAVGKAEERFEEDALRI
                     MRGFRFAASLDFDIEAATFEAMRSHSPLLEKISVERSFTEFDKLLMAPHWRKGISAMIA
                     CQAYDYLPGLKQQEAGLNHLIVSLKDNFTFSDHHQAWAYVMISLAIEDPKSFLKAWKTS
                     NDFQRYVTKLIALYRIRQERSFEKLDIYQYGKEMASLVEGLRKAQSLSVDMDHIEALDQ
                     ALAIHNKYDIVLNGSHLIKDFGMKPGPQLGLMLEKVELAIVEGRLDNDFTTIEAFVREE
                     LAT"
     gene            6373..8250
                     /locus_tag="SD89_RS03420"
                     /old_locus_tag="SD89_03415"
     CDS             6373..8250
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922163.1"
                     /locus_tag="SD89_RS03420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03415"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_053308298.1"
                     /transl_table=11
                     /translation="MSHFLVEKLTKTVGDKTVFQDISFIIHDFDRIGIIGVNGTGKTTL
                     LDVLSGRLGFDGDHSPFSKANDYKIAYLTQDPEFNDASSVLDTVLSSDVKAIQLIRQYE
                     LLMANYTEDKQETLESLMSEMDRLDAWSIESDVKTVLSKLGITDLEQKVGDLSGGMRRR
                     VQLAQVLLGAADLLLLDEPTNHLDIDTIAWLTTYLKTAKKTVLFITHDRYFLDHVATRI
                     FELDKAGLTEYQGNYQDYVRLKAEQDERDATNLHKKKQLYKQELAWMRTQPQARATKQQ
                     ARINRFTDLKKEVHQDSSADKLEMAFETSRIGKKVIHFEDLSFAYGDRQLIKDFNLIIQ
                     NKDRIGIVGDNGVGKSTLLNLINGDLEPTSGKLDIGDTIRVGYFSQQLKDMDETKRVIN
                     YLQEVADEVKTSVGTTSISELLEQFLFPRSSHGTLIAKLSGGEKKRLYLLKLLIEKPNV
                     LLLDEPTNDLDIATLTVLENFLANFAGPVITVSHDRYFLDKVATKILAFEEGDIRVFYG
                     NYSDYLDEKVFEKETVEADLVKTTVTEEVPLPQKEERKRMSYLEKQEWAQIEDKIATIE
                     ANIEEIENQMLTVVSDYDQLAQLQKELDQHNNDLLLAYERFEYLSGLDI"
     gene            8668..8886
                     /locus_tag="SD89_RS10395"
                     /old_locus_tag="SD89_03420"
     CDS             8668..8886
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002995561.1"
                     /locus_tag="SD89_RS10395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03420"
                     /product="hypothetical protein"
                     /protein_id="WP_014407501.1"
                     /transl_table=11
                     /translation="MALLFYYYVRKNQVKKLSQLKNLTEIFRKFIILTINNISAIKVFQ
                     TAGVLFGPVKVANARESSIWFENLTKQ"
     gene            9142..9552
                     /locus_tag="SD89_RS03430"
                     /old_locus_tag="SD89_03425"
     CDS             9142..9552
                     /EC_number="3.5.1.88"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017671.1"
                     /locus_tag="SD89_RS03430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03425"
                     /product="peptide deformylase"
                     /protein_id="WP_002984994.1"
                     /transl_table=11
                     /translation="MIREIITDHFLLQQKAQVAKKEDLWIGQDLQDTLAFYRQECLGMA
                     ANMIGEQKRIVIVSMGFIDLVMFNPVMVSKKGIYQTKESCLSLSGYRKTQRYDKITVEY
                     LDHNWRPKRLSLTGLTAQICQHELDHLEGILI"
     gene            complement(9634..11646)
                     /locus_tag="SD89_RS03435"
                     /old_locus_tag="SD89_03430"
     CDS             complement(9634..11646)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1283: 2`,3`-cyclic-nucleotide 2`-phosphodiesterase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888982.1"
                     /locus_tag="SD89_RS03435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03430"
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="WP_053308299.1"
                     /transl_table=11
                     /translation="MKKYFILKSSVLSILTSFTLLVTDVQADQVDVQFLGVNDFHGALD
                     NTGTAYTPSGKIPNAGTAAQLGAYMDDAEIDFKQANQDGTSIRVQAGDMVGASPANSAL
                     LQDEPTVKVFNKMKFEYGTLGNHEFDEGLDEFNRIMTGQAPDPESTINDITKQYEHEAS
                     HQTIVIANVIDKKTNDIPYGWKPYAIKDIAINDKIVKIGFIGVVTTEIPNLVLKQNYEH
                     YQFLDVAETIAKYAKELQEQHVHAIVVLAHIPATSKDGVVDHEMATVMEKVNQIYPEHS
                     IDIIFAGHNHQYTNGTIGKTRIVQALSQGKAYADVRGTLDTDTNDFIKTPSANVVAVAP
                     GIKTENSDIKAIINHANDIVKTVTERKIGTATNSSTISKTENIDKESPVGNLVTTAQLT
                     IAKKTFPTVDFAMTNNGGIRSDLVVKNDRTITWGAAQAVQPFGNILQVIQMTGQHIYDV
                     LNQQYDENQTYFLQMSGLTYTYTDNDPKNSDTPFKIVKVYKDNGEEINLTTTYTVVVND
                     FLYGGGDGFSAFKKAKLVGAINTDTEAFITYITNLQASGKTVNATIKGVKNYVTSNLES
                     STKINSAGKHSIISKVFRNRDGNIVSSEVISDLLTSTENTNNSLGKKETTINKNTISSS
                     TLPITGDNYKMSPIMTILALISLGGLNAFIKKRKS"
     misc_feature    11622..11635
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.33"
                     /tool="antismash"
     misc_feature    11637..11650
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.93"
                     /tool="antismash"
     misc_feature    complement(11638..11651)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 23.3"
                     /tool="antismash"
     misc_feature    complement(11717..11730)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: medium, score: 22.6"
                     /tool="antismash"
     gene            11866..12516
                     /locus_tag="SD89_RS03440"
                     /old_locus_tag="SD89_03435"
     CDS             11866..12516
                     /GO_process="GO:0015969 - guanosine tetraphosphate
                     metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984988.1"
                     /locus_tag="SD89_RS03440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03435"
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="WP_053308300.1"
                     /transl_table=11
                     /translation="MKERLEHYSTSSIYSGFEVYLPLVLQTITDVIIAENIKSKKETGF
                     KLYEHFTSRIKSEASMIEKCQRKQLPLTSKSALKIIKDSIGIRIICGFIDDIYRMVDLL
                     KSIPGMSVNTEKDYILNAKPNGYRSYHLILELETHFPDILGEKKGCYFIEVQLRTIAQD
                     SWASLEHQMKYKHQVANAEMITRELKRCADELASCDVTMQTIRQLIQETTGEE"
     gene            12519..13187
                     /locus_tag="SD89_RS03445"
                     /old_locus_tag="SD89_03440"
     CDS             12519..13187
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984985.1"
                     /locus_tag="SD89_RS03445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03440"
                     /product="response regulator transcription factor"
                     /protein_id="WP_002984985.1"
                     /transl_table=11
                     /translation="MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAY
                     DIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFS
                     LKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLN
                     QGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
                     "
     gene            13196..14428
                     /locus_tag="SD89_RS03450"
                     /old_locus_tag="SD89_03445"
     CDS             13196..14428
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888981.1"
                     /locus_tag="SD89_RS03450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03445"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_053308301.1"
                     /transl_table=11
                     /translation="MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRILH
                     LISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDREE
                     AQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLAVSM
                     MLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNELVEL
                     MTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSVIAQDAAEDFKSLV
                     LKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCDPKGLVKVSLTTIGRRRKRA
                     KLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFKGTITVNY
                     KNDAIVFTVVI"
     gene            14721..15599
                     /gene="mvk"
                     /locus_tag="SD89_RS03455"
                     /old_locus_tag="SD89_03450"
     CDS             14721..15599
                     /EC_number="2.7.1.36"
                     /GO_function="GO:0004496 - mevalonate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054375.1"
                     /locus_tag="SD89_RS03455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03450"
                     /product="mevalonate kinase"
                     /protein_id="WP_011284695.1"
                     /transl_table=11
                     /translation="MNENIGYGKAHSKIILIGEHAVVYGYPAIALPLTDIEVVCHIFPA
                     DKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRAVF
                     SYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIEIALNGY
                     LVIADTGIHGHTREAVNKVAQFEETNLPYLAKLGALTQALERAINQKNKVAIGQLMTQA
                     HSALKAIGVSISKADQLVEAALRAGALGAKMTGGGLGGCMIALADTKDMAEKISHRLKE
                     EGAVNTWIQML"
     gene            15581..16525
                     /gene="mvaD"
                     /locus_tag="SD89_RS03460"
                     /old_locus_tag="SD89_03455"
     CDS             15581..16525
                     /EC_number="4.1.1.33"
                     /GO_function="GO:0004163 - diphosphomevalonate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /gene="mvaD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011888980.1"
                     /locus_tag="SD89_RS03460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03455"
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="WP_011284696.1"
                     /transl_table=11
                     /translation="MDPNVITVTSYANIAIIKYWGKENQAKMIPSTSSISLTLENMFTT
                     TSVSFLPDTATSDQFYINGVLQNDEEHTKISTIIDQFRQPGQAFVKMETQNNMPTAAGL
                     SSSSSGLSALVKACDQLFDTQLDQKALAQKAKFASGSSSRSFFGPVAAWDKDSGAIYKV
                     ETDLKMAMIMLVLNAAKKPISSREGMKLCRDTSTTFDEWVEQSAIDYQHMLTYLKTNNF
                     EKVGQLTEANALAMHATTKTANPPFSYLTKESYQAMEAVKELRQEGFACYFTMDAGPNV
                     KVLCLEKDLAQLAERLGKNYRIIVSKTKDLPDV"
     gene            16518..17531
                     /locus_tag="SD89_RS03465"
                     /old_locus_tag="SD89_03460"
     CDS             16518..17531
                     /EC_number="2.7.4.2"
                     /GO_function="GO:0004631 - phosphomevalonate kinase
                     activity [Evidence IEA]"
                     /GO_process="GO:0016126 - sterol biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019287 - isopentenyl diphosphate
                     biosynthetic process, mevalonate pathway [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014635411.1"
                     /locus_tag="SD89_RS03465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03460"
                     /product="phosphomevalonate kinase"
                     /protein_id="WP_053308302.1"
                     /transl_table=11
                     /translation="MSNYCVQTGGKLYLTGEYAILTSGQKALIHFIPLMMTAEISPAAH
                     IQLASDMFAHKAGMTPDASYALIQATVKTFADYLGQSIDQLEPFSLIIMGKMERDGKKF
                     GIGSSGSVTLLTLKALSAYYQITLTPELLFKLAAYTLLKQGDNGSMGDIACIAYQTLVA
                     YTSFDREQVSNWLQTMPLKKLLVKDWGYHIQVIQPALPCDFLVGWTKIPAISRQMIQQV
                     TASITPAFLRTSYQLTQSAMVALQEGHKEELKKSLAGASHLLKELHSAIYHPKLVTLVA
                     ACQKQDAVAKSSGSGGGDCGIALAFNQNARDTLISKWQEADIALLYQERWGENDQP"
     gene            17518..18507
                     /gene="fni"
                     /locus_tag="SD89_RS03470"
                     /old_locus_tag="SD89_03465"
     CDS             17518..18507
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984966.1"
                     /locus_tag="SD89_RS03470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03465"
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_010922169.1"
                     /transl_table=11
                     /translation="MTNRKDDHIKYALKYQSPYNAFDDIELIHHSLPSYDLSDIDLSTH
                     FAGQDFDFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDDSYRL
                     HEVADNLKLATNIGLDKPVALGQQTVQEMQPLFLQVHVNVMQELLMPEGERVFHTWKKH
                     LAEYASQIPVPVILKEVGFGMDVNSIKLAHDLGIQTFDISGRGGTSFAYIENQRGGDRS
                     YLNDWGQTTVQCLLNAQGLMDQVEILASGGVRHPLDMIKCFVLGARAVGLSRTVLELVE
                     KYPTERVIAIVNGWKEELKIIMCALDCKTIKELKGVDYLLYGRLQQVN"
     gene            complement(18737..20014)
                     /locus_tag="SD89_RS03475"
                     /old_locus_tag="SD89_03470"
     CDS             complement(18737..20014)
                     /EC_number="1.1.1.88"
                     /GO_function="GO:0004420 - hydroxymethylglutaryl-CoA
                     reductase (NADPH) activity [Evidence IEA]"
                     /GO_process="GO:0016054 - organic acid catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1187: hydroxymethylglutaryl-CoA reductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009880299.1"
                     /locus_tag="SD89_RS03475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03470"
                     /product="hydroxymethylglutaryl-CoA reductase, degradative"
                     /protein_id="WP_010922170.1"
                     /transl_table=11
                     /translation="MTKTNLNWSGFSKKTFEERLQLIEKFKLLNAENLNQLKTDVLLPI
                     QTANQMTENVLGRLALPFSIAPDFLVNGSTYQMPFVTEEPSVVAAASFAAKLIKRSGGF
                     KAQTLNRQMIGQIVLYDIDQIDNAKAAILHKTKKLIALANKAYPSIVKRGGGARTIHLE
                     EKGEFLIFYLTVDTQEAMGANMVNTMMEALVPDLTRLSKGHCLMAILSNYATESLVTTS
                     CEIPVRLLDHDKTKSLQLAQKIELASRLAQVDPYRATTHNKGIFNGIDAVVIATGNDWR
                     AIEAGAHAYASRNGSYQGLSQWHFDQDKQVLLGQMTLPMPIASKGGSIGLNPTVSIAHD
                     LLNQPDAKTLAQLIASVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGATQDEIAP
                     LVNALLADKPINLEKAHFYLSQLRQS"
     gene            complement(20001..21176)
                     /locus_tag="SD89_RS03480"
                     /old_locus_tag="SD89_03475"
     CDS             complement(20001..21176)
                     /EC_number="2.3.3.10"
                     /GO_function="GO:0004421 - hydroxymethylglutaryl-CoA
                     synthase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043: hydroxymethylglutaryl-CoA synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002993959.1"
                     /locus_tag="SD89_RS03480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03475"
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="WP_032464957.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 4.9e-07,
                     bitscore: 26.2, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGIDKIGFATSQYVLKLEDLALARQVDPAKFSQGLLIESFSVA
                     PITEDIITLAASAADQILTDEDRSKIDMVILATESSTDQSKASAIYVHHLVGIQPFARS
                     FEVKQACYSATAALDYAKLHVASKPDSRVLVIASDIARYGVGSPGESTQGSGSIALLVT
                     ANPRILALNKDNVAQTRDIMDFWRPNYSFTPYVDGIYSTKQYLNCLETTWQAYQKRENL
                     QLSDFAAVCFHIPFPKLALKGLNNIMDNTVPPEHREKLTEAFQASITYSKQIGNIYTGS
                     LYLGLLSLLENSKVLQSGDKIGFFSYGSGAVSEFYSGQLVAGYDKMLMTNRQALLDQRT
                     RLSVSKYEDLFYEQVQLDDNGNANFDIYLTGKFALTAIKEHQRIYHTNDKN"
     gene            21385..22224
                     /locus_tag="SD89_RS03485"
                     /old_locus_tag="SD89_03480"
     CDS             21385..22224
                     /EC_number="2.1.1.45"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /locus_tag="SD89_RS03485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03480"
                     /product="thymidylate synthase"
                     /protein_id="WP_011017679.1"
                     /transl_table=11
                     /translation="MTKADQIFKANIQKIINEGSLSEQARPKYKDGRTAHSKYITGAFA
                     EYDLAKGEFPITTLRPIPIKSAIKELFWIYQDQSNSLDVLEAKYNVHYWNEWEVDQTRT
                     IGQRYGAVVKKHDIISKILKQLAENPWNRRNVISLWDYEAFEETKGLLPCAFQIMFDVR
                     RVGEDLYLDASLTQRSNDILVAHHINAMQYVALQMMIAKHFGWKIGKFFYFVNNLHIYD
                     NQFDQAQELLKRQPVASQPKLVLNVPDGTNFFDIKPDDFELQNYDPVKPQLHFDLAI"
     misc_feature    21415..21429
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 23.77"
                     /tool="antismash"
     gene            22304..22801
                     /locus_tag="SD89_RS03490"
                     /old_locus_tag="SD89_03485"
     CDS             22304..22801
                     /EC_number="1.5.1.3"
                     /GO_function="GO:0004146 - dihydrofolate reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005542 - folic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984955.1"
                     /locus_tag="SD89_RS03490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03485"
                     /product="dihydrofolate reductase"
                     /protein_id="WP_053308303.1"
                     /transl_table=11
                     /translation="MTKEIIAIWAEDEAGLIGVAGKLPWYLPKELEHFKKTTLHQAILM
                     GRVTFEGMNCKRLPQRQTLVMTRNRDYQVDEVLTMTSIEKVLEWYHAQDKTLYIIGGNK
                     VLEAFNGYFDRIIKTVIHHRFKGDTYRPNLDFSHFTQERQTFYARDAKNPYDFTVTALK
                     HK"
     gene            22821..22991
                     /locus_tag="SD89_RS09765"
                     /old_locus_tag="SD89_03490"
     CDS             22821..22991
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302775.1"
                     /locus_tag="SD89_RS09765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03490"
                     /product="hypothetical protein"
                     /protein_id="WP_002990165.1"
                     /transl_table=11
                     /translation="MQRSIFGVFTAFLCVICVLCAIPAFKKNRYGLGSLFLLNAFTNLV
                     NSIHAFYGTLF"
     gene            23121..24350
                     /gene="clpX"
                     /locus_tag="SD89_RS03495"
                     /old_locus_tag="SD89_03495"
     CDS             23121..24350
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0046983 - protein dimerization activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="clpX"
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984948.1"
                     /locus_tag="SD89_RS03495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03495"
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="WP_002984948.1"
                     /transl_table=11
                     /translation="MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEI
                     IKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDD
                     DDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLK
                     LIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVP
                     PQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASY
                     MQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDG
                     VELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVE
                     GKSKPVLETA"
     gene            24360..24959
                     /gene="yihA"
                     /locus_tag="SD89_RS03500"
                     /old_locus_tag="SD89_03500"
     CDS             24360..24959
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0043022 - ribosome binding [Evidence IEA]"
                     /GO_process="GO:0042254 - ribosome biogenesis [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="yihA"
                     /gene_functions="other (smcogs) SMCOG1227: ribosome
                     biogenesis GTP-binding protein YsxC"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011054379.1"
                     /locus_tag="SD89_RS03500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03500"
                     /product="ribosome biogenesis GTP-binding protein
                     YihA/YsxC"
                     /protein_id="WP_053308304.1"
                     /transl_table=11
                     /translation="MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSF
                     INTILGRKNLARTSSKPGKTQLLNFFDIDDKLRFVDVPGYGYAKVSKSERAKWGKMIEE
                     YLTTRDNLRAVVSLVDLRHAPSKEDIQMYDFLKYYDIPVIVVATKADKIPRGKWNKHES
                     VVKKALNFDKSDTFIVFSSVERIGIDDSWDAILEQV"
     gene            25107..25850
                     /locus_tag="SD89_RS03505"
                     /old_locus_tag="SD89_03505"
     CDS             25107..25850
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984942.1"
                     /locus_tag="SD89_RS03505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03505"
                     /product="hypothetical protein"
                     /protein_id="WP_002984942.1"
                     /transl_table=11
                     /translation="MTQVAQGRSKGKSLLCHQCNALFVFIIFLILLAVLFGVRYRNSSI
                     EGIWRTTSIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSQMILTVKNNNVDLSFSVQVER
                     DIFVKRLAAYHQNELLKTLKENHLVVGDLSSKERQIIENSMPASHELEMILDQAFEKLA
                     SQIGGKYNQKTGHLSAVVLKGKVNRILHTIDIKEEVAAGHTSFSKGLLTPNGYFDYTRF
                     GKKLELLGDEKIIFKKALKKSPSSV"
     gene            complement(25908..28007)
                     /locus_tag="SD89_RS03510"
                     /old_locus_tag="SD89_03510"
     CDS             complement(25908..28007)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1223: ATPase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922175.1"
                     /locus_tag="SD89_RS03510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03510"
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="WP_053308305.1"
                     /transl_table=11
                     /translation="MTHFSGKDPFVNMDDIFNQLMANMGGYRSENPRYLVNGREITPEE
                     FQHYRQTGQLPVATTKATNSQMLTPKADSVLTQLGTNLTQEARQGHLDPVIGRNKEIQD
                     TAEILARRTKNNPVLVGDAGVGKTAVIEGLAQAIVNGDVPAAIKNKEIVSIDISSLEAG
                     TQYRGSFEETIQNLIQEVKEAGNIILFFDEIHQIVGAGATSSDSGSKGLADILKPALSR
                     GELTLIGATTQDEYRNTILKNAALARRFNEVKVNAPSAEDTFHILMGIRNLYEQHHHIT
                     LPDNVLKAAVDYSIQYIPQRSLPDKAIDLLDMTAAHLAAQHPVTDLKTLETEIAKQKES
                     QEKAVAKEDFEKALAAKTRIETLQKQIEQHNQSQNVTATVNDIAESVERLTGIPVSNMG
                     TNDLERLKGISSRLKSHVIGQDEAVAAVARAIRRNRAGFDDGKRPIGSFLFVGPTGVGK
                     TELAKQLALDLFGSKDAIIRLDMSEYNDRTAVSKLIGTTAGYVGYDDNNNTLTERVRRN
                     PYAIVLLDEIEKADPQIITLLLQVLDDGRLTDGQGNTINFKNTVIIATSNAGFGQQDTE
                     TSESNIMDRIAPYFRPEFLNRFNSIIKFNHLQKENLEEIVDLMLAEVNQTTAKKGISLT
                     IADDAKAHLIDLGYNHAMGARPLRRIIEQEIRDRITDYYLDHPEVKKLQAILKEGQLVI
                     RQKDQ"
     misc_feature    28138..28151
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 22.77"
                     /tool="antismash"
     gene            28405..29538
                     /locus_tag="SD89_RS03515"
                     /old_locus_tag="SD89_03515"
     CDS             28405..29538
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564846.1"
                     /locus_tag="SD89_RS03515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03515"
                     /product="ISAs1-like element IS1548 family transposase"
                     /protein_id="WP_053308306.1"
                     /transl_table=11
                     /translation="MIDFIISIDDCAVELDSRQSWKIRYPLSTILFLVFVCQLADIETW
                     KEMEDFIEMNEPLFATYVDLSEGCPSHDTLERVISLVNSDRLKELKVQFEQSLTSLDAV
                     HQLISVDGKTIRGNRGKNQKPVHIVTAYDGGHHLSLGQVAVEEKSNEIVAIPQLLRTID
                     IRKSIVTIDAMGTQTAIVDTIIKGKADYCLAVKGNQETLYDDIALYFSDVNLLEELQEN
                     AQYYQTVEKSRGQIEVREYWVSSDIKWLCQNHPKWHKLRGIGMTRNTIDKDGQLSQENR
                     YFIFSFKSDVLTFANCVRGHWQIESMHWLLDVVYHEDHHQTLDKRAAFNLNLIRKMCLY
                     FLKVMVFPKKDLSYRRKQRYISVHLEDYLVQLFGERG"
     gene            29711..30394
                     /gene="rpiA"
                     /locus_tag="SD89_RS03525"
                     /old_locus_tag="SD89_03525"
     CDS             29711..30394
                     /EC_number="5.3.1.6"
                     /GO_function="GO:0004751 - ribose-5-phosphate isomerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009052 - pentose-phosphate shunt,
                     non-oxidative branch [Evidence IEA]"
                     /codon_start=1
                     /gene="rpiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009881270.1"
                     /locus_tag="SD89_RS03525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03525"
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="WP_009881270.1"
                     /transl_table=11
                     /translation="MEALKKIAGVTAAQYVTDGMTIGLGTGSTAYYFVEEIGRRVKQEG
                     LQVVGVTTSSVTSKQAEGLGIPLKSIDDIDSIDLTVDGADEVDKDFNGIKGGGAALLME
                     KIVATPTKEYIWVVDASKMVEHLGAFKLPVEVVQYGADRLFRVFEKAGYKPSFRMKGDS
                     RLVTDMQNYIIDLDLGCIKDPVAFGHLLDGTVGVVEHGLFNGMVDKVIVASKDGVTVLE
                     APKAG"
     gene            30471..31682
                     /locus_tag="SD89_RS03530"
                     /old_locus_tag="SD89_03530"
     CDS             30471..31682
                     /EC_number="5.4.2.7"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008973 - phosphopentomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009117 - nucleotide metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0043094 - cellular metabolic compound
                     salvage [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011184417.1"
                     /locus_tag="SD89_RS03530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03530"
                     /product="phosphopentomutase"
                     /protein_id="WP_002990153.1"
                     /transl_table=11
                     /translation="MSKFNRIHLVVLDSVGIGAAPDADKFFNAGVADTDSDTLGHISET
                     AGLSVPNMAKIGLGNISRPIPLKTIPTEDNPTGYVTKLEEVSLGKDTMTGHWEIMGLNI
                     TEPFDTFWNGFPEEILTKIEEFSGRKIIREANKPYSGTAVIDDFGPRQMETGELIVYTS
                     ADPVLQIAAHEDIIPVEELYKICEYARSITLERPALLGRIIARPYVGEPGNFTRTANRH
                     DYAVSPFQDTVLNKLADAGVPTYAVGKINDIFNGSGITNDMGHNKSNSHGIDTLIKTLQ
                     LPEFTKGFSFTNLVDFDANFGHRRDPEGYRDCLHEFDNRLPEIFANMKEDDLLLITADH
                     GNDPTYAGTDHTREYIPLLAYSASFTGNGLIPQGHFADISATVAENFGVDTAMIGESFL
                     GHLK"
     gene            31698..32138
                     /gene="arsC"
                     /locus_tag="SD89_RS03535"
                     /old_locus_tag="SD89_03535"
     CDS             31698..32138
                     /EC_number="1.20.4.1"
                     /GO_function="GO:0008794 - arsenate reductase
                     (glutaredoxin) activity [Evidence IEA]"
                     /codon_start=1
                     /gene="arsC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922177.1"
                     /locus_tag="SD89_RS03535"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /old_locus_tag="SD89_03535"
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="WP_053308307.1"
                     /transl_table=11
                     /translation="MEEITIYHNPNCGTSRNVLAMIRHAGIEPTIIEYLQTPPNRETLI
                     ELLQSMAISAQELLRTNVPEFEAHGLANQAVAEKDVINAMLTDPILINRPIVVTRKGVK
                     LCRPSETLLDILPVPLPSPYMKEDGESVNPIEVKGEKDVIDD"
     gene            32122..32931
                     /locus_tag="SD89_RS03540"
                     /old_locus_tag="SD89_03540"
     CDS             32122..32931
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015647060.1"
                     /locus_tag="SD89_RS03540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03540"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_053308308.1"
                     /transl_table=11
                     /translation="MSLMTKINETKDFLVTKGIETPEFGLILGSGLGELAEEVENAIVI
                     DYADIPNWGKSTVVGHAGKLVYGDLAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKALG
                     CEGVLVTNAAGGIGYGPGTLMAITDHINMTGNNPLIGENLDEFGPRFPDMSDAYTKVYR
                     NKAHEVAEKMNIKLEDGVYMGLTGPTYETPAEIRAFKVLGADAVGMSTVPEVIVAAHSG
                     LKVLGISAITNFAAGFQSELNHEEVVEVTEHIKEDFKGLVKAILAEL"
     misc_feature    complement(33131..33144)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.2"
                     /tool="antismash"
     gene            33597..34310
                     /gene="deoD"
                     /locus_tag="SD89_RS03545"
                     /old_locus_tag="SD89_03545"
     CDS             33597..34310
                     /EC_number="2.4.2.1"
                     /GO_function="GO:0004731 - purine-nucleoside phosphorylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0043096 - purine nucleobase salvage
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="deoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984928.1"
                     /locus_tag="SD89_RS03545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03545"
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="WP_053308309.1"
                     /transl_table=11
                     /translation="MSIHISAKKGDIADKILLPGDPLRAKFIAENFLEDAVCFNEVRNM
                     FGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKTLIRVGTAGAIDPEVHVRELV
                     LAQAAATNSNIIRNDFPEFDFPQIADFGLLDKAYHIAREMGVTTHVGNVLSSDVFYTNM
                     PERNMALGKLGVKAIEMEAAGLYYLAAQHHVKALGIMTISDNLNDPTEDTTAEERQTTF
                     TDMMKVGLETLIAND"
     gene            34303..35091
                     /locus_tag="SD89_RS03550"
                     /old_locus_tag="SD89_03550"
     CDS             34303..35091
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984926.1"
                     /locus_tag="SD89_RS03550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03550"
                     /product="LytR family transcriptional regulator"
                     /protein_id="WP_053308310.1"
                     /transl_table=11
                     /translation="MTNNQTLDILLDVYAYNHAFRIAKALPNIPKTALYLLEMLKERRE
                     LNLAFLAEHAAENRTIEDQYHCSLWLNQSLEDEQIANYILDLEVKVKNGAIIDFVRSVS
                     PILYRLFLRLITSEIPNFKAYIFDTKNDQYDTWHFQAMLESDYEFFKAYLSQKQSRNVT
                     TKSLADMLTLTSLPQEIKDLVFLLRHFEKAVRNPLAHLIKPFDEEELYRTTHFSSQAFL
                     ENIITLATFSGVIYRCEPFYFDDMNAIIKKELSLWRQSIV"
     gene            complement(35172..36077)
                     /locus_tag="SD89_RS03555"
                     /old_locus_tag="SD89_03555"
     CDS             complement(35172..36077)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011284709.1"
                     /locus_tag="SD89_RS03555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03555"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_002984924.1"
                     /transl_table=11
                     /translation="MRIQQLHYIIKIVECGSMNEAAKQLFITQPSLSNAVKDLEMEMGI
                     TIFNRNPKGITLTKDGVEFLSYARQIIEQTSLLEDRYKNHNTGRELFSVSSQHYAFVVN
                     AFVSLLKRTDMTRYELFLRETRTWEIIDDVKNFRSEIGVLFINDYNRDVLTKLFDDNHL
                     TASPLFKAQPHIFVSKSNPLATKSLLSMDDLRDFPYLSYDQGIHNSFYFSEEMMSQMPH
                     NKSIVVSDRATLFNLMIGLDGYTVASGILNSNLNGDQIVAIPLDVPDEIDIVFIKHEKA
                     NLSKMGERFIEYLLEEVTFD"
     gene            36299..36835
                     /locus_tag="SD89_RS03560"
                     /old_locus_tag="SD89_03560"
     CDS             36299..36835
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002990141.1"
                     /locus_tag="SD89_RS03560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03560"
                     /product="hypothetical protein"
                     /protein_id="WP_002984923.1"
                     /transl_table=11
                     /translation="MNVTEQNSHQILIQKLLVSIHYLTLFRDELKLVERTPSILGGEFP
                     AHLVQSELGDIVAAIDTLDMQQRLIESTFWYEESAFKLMNKTLDIVDNWIKGVDHLIDL
                     CQSKEVFQIIIGDKRIRVFGVLSDVFSSLKVSALSLKEAPIPDVLYEHIQRVNLEEEAF
                     IKYYQSPKVPTGEFE"
     gene            37112..37804
                     /gene="pyrF"
                     /locus_tag="SD89_RS03565"
                     /old_locus_tag="SD89_03565"
     CDS             37112..37804
                     /EC_number="4.1.1.23"
                     /GO_function="GO:0004590 - orotidine-5'-phosphate
                     decarboxylase activity [Evidence IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0044205 - 'de novo' UMP biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984921.1"
                     /locus_tag="SD89_RS03565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03565"
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="WP_053308311.1"
                     /transl_table=11
                     /translation="MKEERPIIALDFSSFEETKAFLDLFPAEEKLYVKIGMELYYAQGP
                     DIVRYIKSLGHNVFLDLKLHDIPNTVRAAMAVLKELDIDMATVHAAGGVEMLKAAREGL
                     GQGSTLIAVTQLTSTSEDQMRGDQNIQTSLLESVLHYSKGAAKAQLDGVVCSAQEVEAI
                     KAVTPTGFNCLTPGIRPKGSNIGDQKRVMTPNQARRIGSDYIVVGRPITQAKDPVAAYQ
                     AIKAEWAG"
     gene            37862..38491
                     /gene="pyrE"
                     /locus_tag="SD89_RS03570"
                     /old_locus_tag="SD89_03570"
     CDS             37862..38491
                     /EC_number="2.4.2.10"
                     /GO_function="GO:0004588 - orotate
                     phosphoribosyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009220 - pyrimidine ribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010922180.1"
                     /locus_tag="SD89_RS03570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03570"
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="WP_002984920.1"
                     /transl_table=11
                     /translation="MTLASQIATQLLDIKAVYLKPEDPFTWASGIKSPIYTDNRVTLSY
                     PKTRDLIENGFVETIRAHFPEVEVIAGTATAGIPHGAIIADKMTLPFAYIRSKPKDHGA
                     GNQIEGRVLKGQKMVIIEDLISTGGSVLDAAAAASREGADVLGVVAIFTYELPKASQNF
                     KEAGIKLITLSNYTELIAVAKLQGYITNDGLHLLKKFKEDQVNWQQ"
     gene            38688..40142
                     /locus_tag="SD89_RS03575"
                     /old_locus_tag="SD89_03575"
     CDS             38688..40142
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407508.1"
                     /locus_tag="SD89_RS03575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03575"
                     /product="amidase"
                     /protein_id="WP_053308312.1"
                     /transl_table=11
                     /translation="MTYQDATAMAIAVQTGQTTPLELVTQAIYKAKKLNPTLNAITSER
                     FEAALEEAKQRDFSGLPFAGVPLFLKDLGQELKGHSSTSGSRLFKEYQATKTDLFVKRL
                     EALGFIILGRSNTPEFGFKNISDSSLHGPVNLPKDNTRNAGGSSGGAAALVSSGISALA
                     TASDGGGSIRIPASFNGLIGLKPSRGRMPVGPGSYRSWQGASVHFALTKSVRDTRNLLY
                     YLQMEQMESPFPLATLTKNSIYQSLQRPLTIAFYQRLSDGSPVSLDTAKALRQAVTWLR
                     EQGHQLVELEEFPVNMTEVIRHYYIMNSVETAAMFADIEDTFGRPMTKDDMETMTWAIY
                     QSGKDIPAWRYSQVLQKWDTYSATMASFHETYDLLLTFTTNTPAPKHGELVPDSKLMAN
                     LAQAEIFSSEEQFNLVETMFGKSLAINPYTALPNLTGQPAISLPTYETKEGLPMGIQLI
                     AAKGREDLLLGIAEQFEAAGLLKIPQ"
     gene            40260..41123
                     /locus_tag="SD89_RS03580"
                     /old_locus_tag="SD89_03580"
     CDS             40260..41123
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003061079.1"
                     /locus_tag="SD89_RS03580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="SD89_03580"
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_031488345.1"
                     /transl_table=11
                     /translation="MKKSVTLLSIGLASLLLAACAPHKSQKSSWETIKEKGVLKVATPG
                     TYQPTSFYNDNNELVGYEVDMVKEIGKRLNIKVKFVETGFDQAFTSVDSGRVDISLNNF
                     DITPKRQKKYNISTPYKYGVGGMIVRADGSSNMAKKDLSDWKGKKAAGASGTEYMKVAQ
                     KQGAELVTYDNVTGDVYLNDVANGRTDFIPNDYPAQKLFVDYMLSQNPNLNVKMSDVQY
                     NPTEQGIVMNKKDDSLKKKIDAVIKDMIKDGSLKKISETYYAGQDLTKPFGKDKKIPVI
                     DTKDVN"
ORIGIN
        1 ccataccaaa ttaaatgaat tgattgaatg gtatcaactc actaattttg atggtctgat
       61 gaaatagtta tccacaattt taaaaaaaat cagaagaaat atgtcgattt caagacaaaa
      121 gttatcaatc tcattaaatt atctgtggaa aagttaattt aaacgttcgt gtgctataat
      181 agaaacatag aaaatgtata aaaaaggata tgtgaataat gacaaaaaag aaaggtaagc
      241 ttgtacttat cagtcttttt gttctagcag cttgtttagg agcttatagt gcaatgagac
      301 aatctcataa aacttcaaac gtgtcagctg agactatcgc cagttcttca acccgacatt
      361 ttattgatga aattggtcca actgctagta ctattggtca agaacgtgat ctttatgcgt
      421 ctgttatgat agcacaagcg attttagaat caagtaatgg taaatcaagt ctaagtcaag
      481 caccttatta taattttttc ggtattaagg gtgcctataa cggttcttct gtgacgatgt
      541 caacttggga agatgatggt aatggcaata cctatacgat tgatcaagcc tttagagctt
      601 atccaagtat tgcagactcc cttaatgact atgcagactt gctaagttct agcacttata
      661 taggtgctag aaaatcaaac acgctatcgt atcaagatgc tacagcagct ctaactggct
      721 tatacgctac agacaccagt tataacttaa aactaaataa tattattgca acctatggtt
      781 tgacggctta tgatgttgct aatagctcag ctcaagaaac tggtctagca acttcgggtt
      841 atgtttggaa tgagtatcgt cgtaattaca ctgatgcgga gaccctagca gttgatgagg
      901 cttgggctaa acgcatgact tattaatgta acactaacaa caatctgctt gcactgaccc
      961 caaaaaagct ggatactcta ttttaagtaa aggatttagt tctgtattgt acagaactaa
     1021 atccttttag ttttactttg atatgtttat cgttgtaata atcaatgtca tttgtaatcg
     1081 cttgttctaa gtcttctagt gatttatagt tattctcata accatagaac atttctgact
     1141 ttaagatgcc aaagaaagat tccatcatgc tattgttagg actgtttctt ttacgtgaca
     1201 tagacggacg aattccttta gagtttagga aatgatgata atagttgtgt tgatattgcc
     1261 aaccttgatc actctatcat atagttccat catagcattt atttggagat gtctttttcc
     1321 attattggtt taatgtgatt taagcaaggt tattagctaa acttaatgcc agacaaaaac
     1381 accccaatta ttagattttt tgtctaactt ttggggcgca attcaatctg agcagtttta
     1441 gatttggtat caatgttatt ataggtcaat tgatcatatt tatccaaagc ttttagctta
     1501 tttagtccaa agataaatat caaaatggct gaaatctttc atgtttatag tcttattgtc
     1561 tttatatttt ttaaagacat cagatctggt gctattgggt tttgcgtcat ataaatcgat
     1621 tttttcatgt ttcctatttt tactgtgaat ttctaaactc ccccttatat aaggagactt
     1681 agtcaaatga atttcttttg attccatcaa aaattttctt attttaaaat cgaactcttg
     1741 aatcgtaaca atatccttat cgatttttat aggatttatt aatgtttttt gctgttgccc
     1801 atctataaaa aaattccctg caatagtatt agtccttaga ataccatcat ctgttgaagg
     1861 tattctttct tattgatacg ctttaattgg tctgattcca actatcttgc cctgttgaaa
     1921 gtgtaaataa ccctagtact tgagcaccaa tattatcttc ttttatttct ttagcagaaa
     1981 tagctacttt tccagaggaa ttaacaccaa caaagtattt cttcatacca atagatgcat
     2041 tactatcaga gtctgttaca taaatagctt taaggttccc gttagaatcg aagtcagctc
     2101 cccacaggtt tataacatgg ttgatgcgta cgttagcgta ggtgtgtgat aggcctagag
     2161 ccttgccttc ggttaactct ttcttaatga gatcactgat ttctttgaga tttttttctt
     2221 taaaatcatg acgacttgtc aatagcttac tttgatcacc tcttgtaaat acggcgtcaa
     2281 aaataccacc tcggcgatct ttctcttgat aggttctatt gacatcagta gtctgtgtct
     2341 tataaacatt taagtaataa ccattgataa acatatctaa aacaagatca ggcataactc
     2401 caattcggcg tgctgacaaa ccggggaaag ctttatctcg gaaataatta aaaagctcgc
     2461 tatttgtttg gtcaccttta gtattaataa cttttcttac atccaataat tcttgatcac
     2521 caaacatgat tttttgttta tctgggtgtt tttttagata tgcttcaatt ttttcgttgt
     2581 tttgatcgaa ccaccagtga agcatattcc ctgctgtggc agccccgcaa agaaggtcgt
     2641 cttttccatt gaatgttttg gtaatatcat accatccttg gttagcaaca taaggagcgt
     2701 gaaaaacatc ttcgccttga gtgaagtttg ctggaggaat aactcctttg gtccaaacgg
     2761 aagtaacgtg ataaggtgtt acttccgaat atataatctc ttgattagca gaaaaactat
     2821 ctgctataac accacgatct accgatagag caaataaagt cactgctgcc aatactgcag
     2881 ctgaagttga atagcatctt tttctcataa taataccttt ttctatataa ttttatgata
     2941 aataaattat ataatataga catatattat tgcaagttct taacataata tttaattttt
     3001 aaaataattt ttaataaaat taaacaagcg attgcaatgg agacatcaca agagatacag
     3061 tagtggttgt gcttaaaaat ggacggtttt ttgatgatat gttgctgcat gaggaagtga
     3121 gcaataggag agctgtgata gaagaaagag aggaagaagc gttgatgaaa ttagacaaat
     3181 aaaaaaaaga cctcatccag aagaggtcgt ggtataactg gggacgatag gttcaattga
     3241 taaaaaatct tgttagctta cgatctatgt tgttttgaat gcctttaact caacatcgtt
     3301 aatggatttt gagataaaaa aataaatcca atagtctggt actttcctat tttttgtctg
     3361 ttaaaacgtt tttattttat aatggataaa aggagaagaa gggcggagcg atgattaagc
     3421 tctatgggtt taagtatggg ttagttggag aggttttgcg gcggattgaa cgcctagggt
     3481 ttacgtttga gcgattagag ctaagacaag ctagttcgaa atacttggct aagcatgatg
     3541 aggctttggt gataaacctt tttatcctgg acttaaaact tacctgacca gtggttctgt
     3601 tttaattgag gtgcagtaca agaccactaa cgggtgtttt tttgatataa tgtcagtata
     3661 aggacgacta aatataaata ggtgaaaaaa tagatatctg ttcgagagat agcactgttt
     3721 aaaacgttat gcgaaaatag tagtttaggg gctactttaa taatcttcaa atctatgcta
     3781 taatggatca tattgatacc aaggagaata aaaaatgcaa ttagttcgtg aaaaagaatt
     3841 tgtcaaccag taccattatg atgctagaaa tttagagtgg gaaaaagaaa acggaacacc
     3901 agagaccaat tttgaagtga cttttcagtt gattgataaa gatgagcagc aaaaagaaac
     3961 agtaattgta tctgtattgc aatttgttat tgtcaaagaa gaatttgtta ttagtggggt
     4021 catctcacaa atggttcgta ttttagatcg tttagtggat aaaccaagcg aatttacgca
     4081 agaggaagtt gaatccttag ctgctccttt gctagacatg gttaagcgat tgacttatga
     4141 agtcacagaa attgccttgg atcgtccagg tattcatttg gagtttaaaa attaatgaaa
     4201 ttagcagtaa ttactgacag tacagcaaca ctaccaacag atctgaaaca agataaagct
     4261 atttttagcc ttgatatacc agttatcatt gacgatgaga cctattttga aggtcgaaat
     4321 ttgagtatag atgattttta tcaaaagatg gctgactccc aaaatcttcc caagacaagt
     4381 cagccaagtt tatctgaact agataatctt ttaggacttt tgtcttctaa gggctataca
     4441 catgttattg gcttgttctt agctggagga atctcaggct tttggcaaaa tattcaattt
     4501 ttagctgaag aacatcctga gattgaaatg gcatttccag acagtaagat cacatctgct
     4561 cctttaggta gtatggtaaa aaatgtgcta gattggtcac gtcaaggaat gacatttcaa
     4621 gctattttaa acaagctgca agaacagatt gatgggacga cagcctttat tatggttgat
     4681 gaccttaatc atctggttaa aggcggacgc ctgtcaaatg ggtctgctct tcttggaaat
     4741 cttttgagta ttaaacctat cttacgcttt gatgaagagg gaaaaatcgt tgtttatgaa
     4801 aaagtgagaa cagaaaagaa agccatgaaa cgcttggttg agattttaaa tgacttgata
     4861 gcagacggtc agtataatgt gtctattatt cactcaaaag cacaagacaa agctgattat
     4921 ttgaaacgac tcttacaaga cagtggttat caatatgaca ttgaagaggt tcattttgga
     4981 gcggtgattg ctactcattt aggagaagga gccattgcat ttggcgtaac accgaggctt
     5041 taattgtcga ttagaaaaaa tagttaattg caagaatcac taaaacaata acaaaatgtg
     5101 atagaaccca agtagcttaa tcacacttta gattgggcta cttggatgat aggttagaaa
     5161 acaacgtatg aaattaatga caatgccttc tgagtttcag aaggctttac ccatattgac
     5221 taaaataaaa gaagctggtt atgaagccta ctttgtggga ggaagcgtca gagatgtttt
     5281 actcgagcgt cccattcatg atgtagatat tgcaactagt tcctatcctg aagagactaa
     5341 agcgattttt aacagaactg tcgatgttgg cattgaacat ggtacagtgc tcgtgcttga
     5401 aaatggcggt gagtatgaaa tcacaacctt taggacagaa gatgtctatg ttgactatcg
     5461 ccgtcctagt caggtttctt ttgtgcgctc tttagaggaa gacttaaaac gaagagactt
     5521 taccgtcaat gccttggcct tggatgaaaa tggtcaagtt attgataaat ttagaggact
     5581 cattgatttg gagcaaaaac ggttacgagc agtgggtaaa gcagaggaac gttttgaaga
     5641 agatgcacta cgcattatga gaggctttcg atttgcggcg agtctggatt ttgacattga
     5701 agctgcaact tttgaagcta tgaggagcca ttcacctcta ttggaaaaga tttctgtgga
     5761 acgttctttt actgaatttg ataaattatt gatggcaccg cactggcgaa aagggatttc
     5821 tgccatgatt gcttgtcagg cttatgacta tttaccaggc ttgaagcagc aggaagcagg
     5881 cttgaatcat ctgatagttt ctttgaaaga taactttacc tttagtgatc accaccaagc
     5941 ttgggcttat gtgatgatta gtttagccat tgaggatcct aaaagcttcc taaaagcatg
     6001 gaagacttca aatgattttc agcgttatgt cacaaagttg attgctcttt atagaattcg
     6061 tcaggaaaga tcttttgaaa aattggatat ttaccagtac ggcaaggaaa tggcaagtct
     6121 agtggaaggc ctccgaaaag ctcaaagctt atctgttgac atggaccaca ttgaagcttt
     6181 agatcaagcg ctagccattc ataacaaata cgatatcgtc cttaatggtt ctcacctgat
     6241 taaggatttt gggatgaaac caggtcctca gctagggctt atgcttgaga aagttgaatt
     6301 agcgattgta gagggacgcc tagataatga tttcactaca attgaagcat ttgttagaga
     6361 ggaattagca acatgagcca ttttttggtg gagaaattga caaaaacggt gggagataaa
     6421 acagtctttc aggatatttc ctttattatt catgactttg accgtattgg gattattggg
     6481 gttaatggaa caggaaaaac aactctttta gatgtcttgt cgggaaggct tggttttgac
     6541 ggagaccatt caccattttc taaagccaat gattacaaaa tcgcttactt aacacaagat
     6601 cctgaattta acgatgcatc ctctgtttta gatacggtat tgtcatctga tgttaaggcg
     6661 attcagctga ttcgtcagta tgaactattg atggcgaatt atactgaaga taaacaagag
     6721 accttagagt ccctcatgtc tgaaatggat cgcttagatg cttggtctat tgaaagtgat
     6781 gtcaaaacag tcctatcaaa attaggcatc acggatttgg aacaaaaagt gggagaccta
     6841 tcaggtggta tgagaagacg tgtccagtta gctcaagtat tgctaggagc tgctgactta
     6901 ctcttgttgg atgagccgac caaccatctc gatattgaca ccatcgcttg gttaacaacc
     6961 tatctcaaga cagctaaaaa aaccgtcctt tttattaccc atgaccgtta tttccttgat
     7021 catgtggcta cccgtatttt tgaattggat aaagcgggac tgacagaata tcaaggcaat
     7081 taccaagact atgtgcgctt aaaagcagaa caagacgaac gagatgctac taatttacac
     7141 aagaagaagc aactctataa acaagaatta gcttggatga ggacgcagcc acaggcgcgt
     7201 gcaaccaaac agcaggctag aatcaatcgt ttcactgact tgaaaaaaga agttcaccaa
     7261 gacagttctg cagataaatt ggagatggct ttcgaaacga gccgaattgg gaagaaggtg
     7321 attcactttg aagacctttc ttttgcttat ggcgaccgac agttgattaa ggattttaac
     7381 ttgattattc aaaataaaga tcgtattgga attgttggag ataacggcgt cggaaaatct
     7441 accctgttga atttaattaa tggagatctt gaaccaactt ctgggaagct tgatattgga
     7501 gatactattc gtgtaggtta tttctctcag cagctcaaag atatggatga gaccaaacgg
     7561 gtcattaatt accttcaaga agtggctgat gaggttaaaa caagtgtggg aacaacgagt
     7621 atcagtgagc ttttagaaca atttcttttt ccgagatcaa gtcatggcac gctgattgct
     7681 aaattatctg gtggggagaa aaaacggctc tacttgctaa aactgctcat tgaaaagcca
     7741 aatgttcttc tccttgatga gccaacaaat gatttagaca ttgccacctt gacggtctta
     7801 gaaaactttt tagctaactt tgcaggacca gtcattacgg ttagtcacga tcgttatttc
     7861 ctagacaaag tagctactaa gattttagcc tttgaagaag gcgatattcg tgttttttat
     7921 ggcaattaca gtgattacct tgatgaaaaa gtttttgaaa aagaaacagt tgaggctgac
     7981 ttggttaaaa caacagtcac tgaagaagtg ccacttcctc aaaaagagga aagaaagcgc
     8041 atgtcctacc ttgaaaaaca agaatgggct cagatagaag ataaaatagc aactattgag
     8101 gctaatattg aagaaattga aaaccaaatg ttaactgtag ttagcgatta tgaccagtta
     8161 gctcaattac aaaaggaact cgatcagcac aataatgatt tattattggc gtatgaacgg
     8221 tttgagtatt tgagtggact agacatataa gaatactatg gtaatgttat gtttataata
     8281 aacaagtgat aatagaaaag aagtgctctt gcactgagcc ccaaaagttg gctactctat
     8341 ttgaagtaaa ggatttagtt ctgtgttgta gaggactaag tccttttcgt tttattttga
     8401 tacgtttatt gttgcaataa tcgatgataa tagtaggtag aacgagtcac tttagccgtt
     8461 cttaaaagaa aatctaatca gaactcgtct ttgtccattc tttataatgg ttttttgtct
     8521 tcttctttgc agagatgctt ctttcaaacg gagttccctc ggttttttta gcgctaaata
     8581 tctagcttat cttcatagct taatgtcata caaaaacacc ccaaacgtta gattttttta
     8641 tctaacgttt ggggtgtagt ttacattatg gcgcttcttt tctattatta cgtgaggaaa
     8701 aatcaagtaa aaaagttaag tcaactgaaa aacttgacag aaatattcag aaaatttata
     8761 atactaacta ttaacaacat atcagctatt aaagtatttc aaacagcagg tgttttattt
     8821 ggacctgtta aggttgcaaa tgcaagagaa agcagtatct ggtttgaaaa tctcacaaag
     8881 caataactat ctctcttaga catttgaaga agcagacagt aaattcgata atattgtgat
     8941 gagaacttag caacaatctg ctgatgcagg tcaattttta tttggtactc atattgcaga
     9001 atttcataaa gttgcccaag atatcttgaa ataaggaatc acctgatgtt ttaaacagat
     9061 gatactaagt ctatcatatg gtgataatag tccattgaac atgtagttta tgaattaaaa
     9121 agaaggttta aggagataag aatgattaga gaaatcataa cagatcattt tttattacag
     9181 caaaaagcgc aagtcgccaa gaaagaagat ctatggattg gccaagattt acaagatacc
     9241 ttagcctttt atagacagga atgtcttggg atggctgcca atatgattgg tgaacaaaag
     9301 cgcattgtta ttgtgagtat gggatttatt gatttggtta tgtttaatcc tgtgatggtt
     9361 tctaaaaagg gaatttacca aactaaagaa tcttgtttgt cgttatctgg ctatcgcaaa
     9421 acacagcggt atgataagat tactgttgag tatttggacc ataattggcg accaaagcga
     9481 ttaagcttaa caggcttaac tgctcaaata tgccagcacg aattagatca tctagaaggt
     9541 attttaattt aacaaaaaac ctagagtagg acgctttagg tttttttggc aaagatgcct
     9601 gattatataa gggtgatcga ttactagtaa acgctaggat ttcctttttt taataaaagc
     9661 gtttagtcca cctaagctta tcaaggcaag gattgtcata ataggagaca ttttataatt
     9721 gtcccctgtt attggaagag tggaactaga gatagtattt ttgtttatcg ttgtttcttt
     9781 tttgccaagg ctgttattag tgttttcagt agaagtcaaa aggtctgaaa tgacttcact
     9841 agacactata ttgccatcac gatttctaaa aaccttacta atgatactgt gtttaccagc
     9901 actattaatt tttgttgagc tttcaaggtt tgaagttaca taatttttaa cccctttgat
     9961 agtagcatta acagttttac ctgatgcttg taaatttgtg atatatgtga tgaaagcttc
    10021 agtatctgtg ttaatagctc cgactaattt agctttttta aatgctgaaa agccatcacc
    10081 gccaccataa agaaagtcgt tgacaacaac ggtgtaagta gttgttaagt taatttcttc
    10141 accattgtct ttataaacct taactatctt gaagggggta tcagagttct taggatcatt
    10201 atctgtataa gtgtatgtta aacctgacat ttgaagaaaa taggtctggt tttcatcgta
    10261 ttgctgattt aggacatcgt aaatgtgttg accagtcatt tgaatgactt gaaggatatt
    10321 accaaatggt tgtacagcct gtgcagctcc ccaggtgatg gtccggtcat ttttgacaac
    10381 taggtcactt cgaataccac cattattggt catagcaaag tcaacagttg gaaaagtttt
    10441 cttagcaata gtaagctgag ccgttgttac taagttaccg acaggggatt ctttatcaat
    10501 attttctgtt ttagaaatag ttgaagaatt agttgcagtt ccgatttttc gttcagtaac
    10561 tgttttaaca atatcattag catgatttat tatagctttg atatctgaat tttctgtttt
    10621 gatacctggt gctacagcaa caacatttgc tgatggagtt ttaataaaat cattggtatc
    10681 agtatctagc gtaccacgga catctgcata agcttttcct tgagagaggg cttgaacgat
    10741 acgtgtttta ccgatagttc cattagtgta ttgatgatta tgtcctgcaa aaataatatc
    10801 aatactatgt tcgggataga tttggttcac tttttccata accgtagcca tttcatgatc
    10861 aacaacacca tctttacttg ttgcaggaat atgagctaaa accacaatag catgaacatg
    10921 ttgttcttgc agttctttag catatttggc aatggtttca gctacatcta aaaattgata
    10981 gtgttcatag ttttgcttta aaacgagatt tggaatctct gtagtcacaa caccaatgaa
    11041 gccaatctta acgattttgt cattaatggc tatgtctttt atagcataag gtttccaacc
    11101 ataggggata tcattggttt ttttatcaat gacattagca atgacgatgg tttgatgcga
    11161 agcttcgtgc tcatattgtt tggtgatatc attaattgtt gattcaggat caggcgcttg
    11221 acctgtcatg atacggttaa attcatctag tccttcgtca aattcatgat taccaagagt
    11281 gccatattca aatttcattt tgttaaagac tttcacagta ggctcatctt gtaaaagtgc
    11341 agagttagca ggactggctc cgaccatatc tccagcttga acacgtatac ttgttccgtc
    11401 ttgatttgct tgcttgaaat ctatctcagc gtcatccata taagcaccta attgagcagc
    11461 cgtcccagca tttggtattt taccacttgg tgtgtaagct gttccggtat tatcaagagc
    11521 gccgtgaaaa tcattgacgc caaggaattg cacatcaact tgatctgctt gaacgtctgt
    11581 aactaataga gtaaaactag tcaggatact caatacacta ctttttaaaa taaaatattt
    11641 tttcataaaa tctcctaata agttaacgta atcgttatag atcaagttta ctatgatttt
    11701 gtttgtaatt caatggtatt tttaaaaaat aacgtataaa aaatatatga aagcgattta
    11761 aaaacaaacg atatagatca tttgcagtta tatagttaga aataaagatg accgatcatt
    11821 gcagagattt aagcatttgt tgagaaaatt tgttataata agcgtatgaa agaaagacta
    11881 gaacattatt ctaccagctc tatatatagc ggatttgaag tgtacttgcc gttggtacta
    11941 cagacaataa cagatgtgat tattgctgag aatatcaaaa gcaaaaaaga aacagggttt
    12001 aaactatacg aacactttac atcccgtatt aaatcggaag cttcgatgat tgaaaaatgt
    12061 caacgcaaac agcttcctct aacaagcaaa tctgcgttaa aaatcattaa agatagtatc
    12121 ggtattcgca ttatttgtgg ttttattgat gatatttatc ggatggtaga cttgctcaaa
    12181 agcattcctg gtatgtcagt taacactgaa aaagattata ttttaaatgc caagcctaat
    12241 ggctatagat catatcatct cattttggaa ttagaaacac attttccaga tattttaggg
    12301 gaaaaaaaag gatgttattt tatagaagtg cagttgcgaa ccattgctca agactcttgg
    12361 gctagcttgg aacatcaaat gaagtacaaa catcaagttg ctaatgcaga aatgattaca
    12421 agagagttaa agcgttgtgc agacgagttg gcatcttgtg atgttaccat gcaaaccatt
    12481 cgtcaattga ttcaagaaac gacgggggaa gagtaactat gaaaattttg ttagctgaag
    12541 acgaatggca aatgtctaat gttttgacaa ctgccatgac tcatcaaggt tatgacgttg
    12601 atgtggtttt taacggtcaa gaggcaattg ataaagccaa agacaatgca tatgatatta
    12661 tgattttaga tatcatgatg ccgattaagt ctggcattga ggctttaaag gagattcgcg
    12721 cttcaggaaa ttgctcacat attattatgc tgacggctat ggcagaaatt aatgaccgtg
    12781 ttaccggact agatgcggga gctgatgatt atctgactaa acctttctca ttaaaagaac
    12841 ttttagctag attaaggtcg atggaaagac gagtagaaag ttttactcct caggtattac
    12901 aatttgctgg tgtcacatta aatattaatg agcaagaatt gagtgccggt aatgctatac
    12961 gattagcttc taaagaaggt aaattaatgg cctttttaat gttaaatcaa ggaaagtact
    13021 tggatactaa aacgctttac caacatgttt ggtcagacca agaagattat gatacttcta
    13081 ttgtttgggt ttatatttct taccttcgtc aaaaattatt agctattcaa gcaaatgtca
    13141 ttattgcagg tgataaagat actagctatt gtttattaga aaaataggag gtgacatgtt
    13201 taatcgtatc cgtattcgtt ttatcatgat tgcttctatt gccattttta ttattttgag
    13261 ttcaattgtt ggtattatta acacggcacg ctgttaccaa agtcaacaag aaattaaccg
    13321 tattttacat ttaatttcct caaataaagg taaattacct ggcactacgg aaagctctaa
    13381 acgacttgga acgaaactgt ctgaagatag cctaagccag tttcggtatt atagtgtcat
    13441 ttttaatgct aatggacatc tactttcttc taatactgct aatatttcag ctttagatag
    13501 agaagaagcc caatattttg ctagactttt tgctaagtct ggggaagaaa aaggcagtta
    13561 ccgtcaccaa gatagtgttt attcgtactt gattactcag ctgccaaatg aagaaaaact
    13621 ggttgttatt ttagatacta ccttttattt tcgtagtgta ggagatttat tagctgtttc
    13681 aatgatgttg gcctttggag gatttatctt ttttgttgtt ttagtgagtc ttttttccgg
    13741 tatggtcatc aaaccttttg tccaaaatta tgagaagcag cgccgcttta ttactaatgc
    13801 aggccacgag ttaaaaacac cactagccat tatctcagcc aataatgaat tggtcgaatt
    13861 aatgactgga gaatcagaat ggaccaagag tacaagtgat caggtgaagc gattgacagg
    13921 cttgattaat caaatgatta ctttggctcg tttggaggaa cagccagatg tggtattaca
    13981 tatggtagac ttttcagtta ttgctcaaga tgcagctgaa gattttaaga gtctggtttt
    14041 gaaagatggt aaacgttttg atttgacgat tcagccgaat attatgatta aagcggagga
    14101 aaagtcatta tttgaacttg tgacaatttt agttgataat gccaataaat attgtgatcc
    14161 taaaggcttg gtcaaggtat ctttaaccac tattggaaga agacgaaaac gagcgaaatt
    14221 agaagtttct aatacctatt tggaaggaaa atccattgat tacagccgct tttttgaacg
    14281 cttttatcgc gaagacgaat cccataatag caaagaaaaa ggttatggaa ttggtttatc
    14341 tatggcagaa agtatggtta agttatttaa aggaacgata actgtaaatt ataaaaacga
    14401 tgctattgtt tttacagtgg tgatttgact taaacatttt tcagtacctt tagctagtaa
    14461 taatgtctag gtaaaggtaa taaacgatgc ttaaccagcc catgaggctg gttttaacgt
    14521 ttaatttagt agaagagtga ttaaagaagg tagtttgaaa taagaaaatt tttgttatga
    14581 tcctaaaaag agtagatagt ctttattgtt aatttcagtg aagaaatgat tttaaaaaga
    14641 tatatcatcg cattttctaa tcatttagtg taaaatagta aggtaaaagt ttagaagaat
    14701 tagtaatgaa aagataaaaa atgaatgaaa acattggata tggtaaggca cacagtaaga
    14761 tcattttgat aggtgagcat gctgttgtgt atggctaccc agctattgct ttgcctttaa
    14821 cagatattga ggtggtttgt catatttttc cagctgataa gccattggtc tttgattttt
    14881 atgatactct atcaacagcc atttatgctg ccttggatta tttgcagcga ctacaagaac
    14941 caattgctta tgagattgtt tcacaagtgc cacaaaagcg tggtatgggg tcttcggcag
    15001 ccgtttctat tgcagctatt agagccgttt tttcttattg tcaagaaccc ctctcggatg
    15061 atttgttgga aattttagtc aacaaggcag aaattattgc ccacaccaat cctagtggtt
    15121 tagatgccaa gacatgcctt agtgaccatg ccattaagtt tatccgaaac attggctttg
    15181 aaactatcga aatcgcctta aatggttatc ttgtcattgc agatacaggg attcacggtc
    15241 atacacgtga ggccgtcaat aaggtagcac agtttgagga aacgaatttg ccctatctgg
    15301 ctaaactagg agctttgaca caagcccttg aaagagcgat taaccaaaaa aataaggtgg
    15361 ctatcggtca gctcatgaca caagcgcact ctgctttaaa ggccattggc gttagcatca
    15421 gtaaagctga ccaacttgtg gaggctgccc taagagcagg tgctttaggc gctaagatga
    15481 caggcggtgg cttgggtggc tgtatgattg ccctagcaga taccaaagac atggccgaaa
    15541 aaatcagtca cagattaaaa gaagaaggag ccgtaaacac gtggatccaa atgttataac
    15601 cgtaacatcc tatgctaaca ttgctattat caaatattgg ggaaaagaga atcaagctaa
    15661 gatgattcct tcgacctcta gcatttcttt gactttggaa aacatgttca ccacaaccag
    15721 cgtttccttc ttaccagata ctgcaaccag tgatcagttt tacattaacg gtgtcttgca
    15781 aaatgacgaa gaacatacca aaatttctac tatcattgac caatttcgcc aacctggtca
    15841 ggcttttgta aagatggaaa ctcaaaataa tatgccaaca gctgcaggtt tatcatcaag
    15901 ttccagtggc ttatcagcct tggttaaagc ctgtgatcaa ttatttgaca ctcagctaga
    15961 tcagaaagct ttagctcaaa aggctaagtt cgcctcagga tcatcttctc gttctttttt
    16021 tggcccagtt gctgcttggg acaaagatag tggtgctatt tacaaggttg agactgactt
    16081 gaaaatggcc atgattatgc tggtcttaaa tgctgcgaaa aagccaattt ctagccgaga
    16141 gggcatgaag ttatgccgcg atacctcaac tacatttgat gaatgggtag aacaatcggc
    16201 aatcgattac caacatatgc ttacctatct caaaactaat aattttgaga aagttggtca
    16261 gttaacagaa gctaatgcct tggccatgca tgccacgaca aagacagcca atcctccctt
    16321 ttcttaccta acaaaagagt cttaccaggc tatggaggct gtgaaagaac tgcgtcaaga
    16381 aggttttgct tgttatttta ccatggacgc aggtccaaat gtgaaggtcc tatgtttaga
    16441 aaaagacttg gctcaactag cagaacgact tggcaagaac taccgtatta tcgtttcaaa
    16501 aacaaaggat ttaccagatg tctaattatt gtgtgcaaac aggtgggaaa ctatacctca
    16561 caggcgaata tgctatctta acatcaggac aaaaagcctt aattcacttt attccactga
    16621 tgatgacagc agaaattagc ccagcagccc atattcaatt agcttcagat atgtttgccc
    16681 ataaagcggg catgacaccc gatgcttctt atgcactgat tcaagcaacg gttaaaacct
    16741 ttgctgatta tctaggacag tcaattgacc aactggagcc attttcctta atcataatgg
    16801 gaaaaatgga gcgcgatggc aaaaaatttg gcattggttc aagtggtagc gtcactctct
    16861 taaccttaaa ggctttatcg gcctattatc agatcacttt aaccccagag ttactcttta
    16921 aactagcggc ttataccttg cttaagcaag gagataatgg gtctatgggg gatattgcct
    16981 gtatcgctta tcagacttta gtcgcctata cctcctttga ccgagaacag gtcagtaact
    17041 ggctgcagac catgccctta aaaaaacttc tcgtcaaaga ttggggttac catatccaag
    17101 tcattcaacc agccttgcct tgtgactttt tggttggctg gactaaaata cctgctattt
    17161 caaggcagat gattcaacaa gtgacagcga gcattacccc agctttctta agaacaagtt
    17221 accagctaac gcaatcagct atggtagctt tgcaagaagg tcataaggaa gaactcaaga
    17281 aaagtttagc aggagcaagt catctcctaa aagagcttca ttcagctatc taccatccta
    17341 agctagtaac cttggtagct gcttgtcaga agcaagatgc tgttgctaaa tcttcaggtt
    17401 ctggtggtgg agattgtggc atcgcgcttg cctttaatca gaatgccaga gataccctta
    17461 tttccaaatg gcaagaagct gatatcgcat tactttatca agaaaggtgg ggagagaatg
    17521 accaaccgta aagatgatca catcaaatat gccctcaagt accaatcgcc ttataatgct
    17581 tttgatgaca tagaactcat acatcattcc ttacctagct atgatttgtc tgatattgat
    17641 ctcagtactc attttgccgg gcaagacttc gactttccct tttacatcaa tgccatgaca
    17701 ggaggaagtc aaaaaggcaa agctgtcaat gaaaaattgg ccaaagtagc agcagcaaca
    17761 gggattgtca tggtgacagg gtcttatagc gctgctttaa aaaatcctaa cgacgattcc
    17821 tatcgtttac atgaggtggc agataacttg aaactagcca cgaatattgg tctagataaa
    17881 cctgtggcgc taggacaaca aacggttcaa gaaatgcagc ccctcttttt acaggttcat
    17941 gtgaatgtga tgcaagagtt gctgatgcca gagggtgagc gcgtctttca tacctggaaa
    18001 aaacacctcg ctgaatacgc tagtcaaata ccagttcctg tcattctcaa agaagttggt
    18061 tttggcatgg atgtcaatag tatcaagcta gcacatgacc taggcattca aacctttgat
    18121 atttcaggaa gaggagggac ctcatttgcc tatattgaaa atcaaagagg aggagaccgc
    18181 tcttacttaa acgattgggg acaaaccacc gttcagtgct tgctaaatgc acaaggactg
    18241 atggaccaag tggaaatctt agcttcgggt ggtgtcagac accccttgga catgattaaa
    18301 tgtttcgtcc taggagcacg tgcagtggga ctctcacgca ccgttttaga attggtcgaa
    18361 aaatacccaa ccgagcgtgt gattgctatc gttaatggct ggaaagaaga attaaaaatc
    18421 attatgtgtg ctcttgactg taaaactatt aaagaattaa agggagtcga ctacttacta
    18481 tatggacgct tgcagcaggt caattaggct tcatcacctc tacaatagtg ccacctacta
    18541 caaagatgat agagcttttt tagaacataa tataaaatat ttataaatac ctcatcaaac
    18601 tcagaataga gtagatgagt aaatagagta tgttatggag actatttcta agacttgtat
    18661 gtatagaaac aaagattaaa cacccatgta aaccaattgt ttacatgggt gtttgcctta
    18721 tattagttgt ttaaatctaa gactgtctta gctgggataa gtaaaaatgt gctttttcta
    18781 gatttattgg tttatcagct agtaaagcat taactaaagg agcaatttcg tcttgggttg
    18841 cccccgccaa aagagctaat gatttcgcat gtagtttcat gtgaccagct tggatgccag
    18901 atgaggtcag agcttttagt gcagcaaagt tttgagctaa ccccacagat gcaatcaatt
    18961 gggctaatgt tttggcatca ggttgattaa gaagatcatg tgcgatagaa acagtagggt
    19021 taagcccgat agatcccccc ttactagcaa taggcatagg gagggtcatt tggccaagca
    19081 gaacttgttt atcttggtca aaatgccact gactaagtcc ttgatagcta ccatttcttg
    19141 aggcataagc atgggcccct gcttcaatag cacgccagtc atttcctgtg gctattacca
    19201 ctgcatcaat gccattaaaa atacctttat tatgagtagt agcccggtaa ggatctactt
    19261 gagctagtcg gctggctagc tctatttttt gagctaactg tagggatttt gttttatcgt
    19321 gatctaaaag gcgcacggga atctcacaac tagtagtaac aagcgactct gttgcgtaat
    19381 tagataaaat cgccattaga caatgcccct tagacagtct tgttaaatca ggaacaagag
    19441 cttccatcat agtattgacc atatttgctc ccatagcttc ttgggtatca acagtcagat
    19501 agaaaatcaa aaattctcct ttttcttcca aatgaatggt tctagcgcct ccacctcttt
    19561 taacaatgga aggataagct ttatttgcca atgcaattag cttttttgtt ttatgaagga
    19621 tggcggcttt agcgttatct atttggtcga tatcgtaaag aacaatttga ccaatcattt
    19681 gtcggtttag ggtttgagct ttaaaaccac ctgagcgttt gattagtttt gctgcgaaag
    19741 atgctgcagc aacaacagaa ggttcttccg tgacaaaagg catctgataa gttgaaccgt
    19801 tgacaagaaa atcaggagct atgctaaagg gcaaagccaa tcgtcctaag acattttcag
    19861 tcatttgatt agctgtttgg ataggcaaaa gaacgtctgt tttgagttga tttaagtttt
    19921 cagcattaag tagtttaaat ttttcgataa gttggaggcg ttcttcgaat gttttctttg
    19981 aaaaaccgct ccagttaaga ttagtttttg tcattggtat gatagatcct ttgatgctcc
    20041 ttgatggctg ttagagcaaa ttttccagtt aagtaaatgt caaaattggc attaccatta
    20101 tcatctaatt ggacttgttc gtagaaaagg tcttcgtatt tagaaacgga aagacgtgtt
    20161 cgttgatcta gtaaagcttg tcgattagtc attaacattt tatcgtaccc agcaactaac
    20221 tgaccggaat aaaattcact tacggcaccg gaaccatagc taaaaaaacc aattttatct
    20281 ccagattgta atactttact attttcaagt aaagataaca atcctagata aagtgagcca
    20341 gtataaatat ttccaatttg tttgctataa gtaatagaag cttgaaaggc ttctgttagt
    20401 ttttctctgt gttcaggagg tactgtgtta tccataatgt tatttagacc ttttagggct
    20461 aacttgggaa atggaatatg gaaacaaact gcagcaaaat cagataactg aaggttttct
    20521 cttttctgat aagcttgcca cgtggtttct aagcaattga gatattgctt ggtagagtaa
    20581 ataccatcaa cataaggtgt gaaactatag ttaggcctcc aaaagtccat aatatcccta
    20641 gtttgagcca cattatcttt atttagagca agaatacgag ggttagcagt taccaaaaga
    20701 gcaatactac cagagccttg agttgattcg ccaggagacc ctacaccgta tctagcaata
    20761 tcactagcaa taacaaggac acgagaatct ggcttagaag ccacatgcag tttagcatag
    20821 tctagagcag cagttgcgct atagcaggct tgttttactt caaaggaacg tgcaaaaggc
    20881 tggataccaa ctaagtgatg tacatagata gctgatgcct ttgactgatc agtactcgat
    20941 tcagttgcca aaataaccat atcaatctta gatcgatctt cgtcggttaa gatttgatct
    21001 gctgcagaag cagctaaagt aataatgtct tcagtgattg gtgccacact aaaagactca
    21061 atgagtagcc cttgactaaa ttttgctgga tccacttggc gtgcaagcgc taaatcttcc
    21121 aatttcaaga catattgact ggttgcaaaa ccaatcttat caattccaat tgtcatattt
    21181 gtccttcttt tagttatttt tatagtctta cccattctat cacattttac tgcaaaatta
    21241 gactgataaa gttatttgtt ttatccttta atagttaaaa tattcatgac cacatgaagt
    21301 ttttcgaatg tttatttatt ctggtatttt ttggtaaaat tagttagaat agtatgaagt
    21361 atgcttacag aaaggttatt agagatgaca aaagctgacc agatttttaa agctaatatt
    21421 caaaaaatta taaacgaagg atcattgagt gagcaagcac gtcctaaata taaagatggc
    21481 cgaacagctc attctaagta tattactggg gcgtttgctg aatatgattt agctaaagga
    21541 gagtttccca tcacaacttt acgacccatt ccaattaaat ctgctataaa ggaattattt
    21601 tggatatatc aagatcagtc taacagttta gatgtgctag aagctaaata taatgttcat
    21661 tattggaatg aatgggaagt tgaccagaca cgtactattg ggcaacgtta tggtgctgta
    21721 gtcaaaaaac atgatatcat ctcaaaaata ctaaagcaat tagcagaaaa tccttggaat
    21781 cgtcgtaatg tcatttctct ctgggactat gaagcatttg aggagacaaa aggattgttg
    21841 ccatgtgcct ttcaaatcat gtttgatgtt agacgtgtag gggaagatct ttatttagat
    21901 gctagtttga cgcaacgttc taatgacata ttagttgctc atcacatcaa tgccatgcaa
    21961 tacgttgcct tgcagatgat gattgctaaa cattttggat ggaaaatagg taagttcttt
    22021 tattttgtta acaatttaca tatttatgac aaccaatttg atcaggctca agaattacta
    22081 aaacgacagc cagttgctag tcagcctaag cttgttttaa atgttccaga tgggactaat
    22141 ttctttgata ttaaaccaga tgattttgaa ttacaaaatt atgatccagt gaagcctcag
    22201 ttgcactttg accttgctat ttaaactcta tttagatttt ttgtgagcat tttgttcata
    22261 aatttggtaa aataaataga gtttaaaatg aaggaaataa ttaatgacaa aggaaattat
    22321 tgctatttgg gcagaggatg aagcagggct tattggtgtt gcgggtaagt taccatggta
    22381 tttaccaaaa gagttagaac attttaaaaa gacaacgcta catcaagcaa tcttaatggg
    22441 ccgtgtgact tttgaaggaa tgaattgcaa aagacttcct caacgtcaaa cccttgtcat
    22501 gacaagaaat agagattatc aagtagatga ggtgttgaca atgactagta ttgaaaaagt
    22561 cttggagtgg taccatgcgc aggataaaac actttatatc attggtggga ataaggtttt
    22621 agaagcgttt aatggttatt ttgatcgtat cataaaaaca gttatccatc atcgttttaa
    22681 aggagatacc taccgaccca atctagattt tagtcatttc acgcaagaaa gacaaacgtt
    22741 ctatgctcga gacgctaaaa atccttatga ttttaccgtt actgctttaa aacacaaata
    22801 gtctgaggag atgataagcg atgcaacgta gtatttttgg agtatttacg gcttttttgt
    22861 gcgtgatttg tgttctttgt gccatcccag cttttaaaaa gaatcgttat ggcttaggaa
    22921 gtctgttctt attaaatgcg tttactaatc tggttaatag tattcacgcc ttctatggta
    22981 cattgttttg agatgcgact tgcaaagaca gcactggtga agatttagct atcaagcaag
    23041 aatcaccaaa aaccaataca acacattgac taatattaaa attcattaaa agataagaga
    23101 aagtaagaga attataagaa atggcaggaa gtagaactaa cgatattaaa gtatactgtt
    23161 cattttgtgg taaaagccag gatgacgtta aaaaaattat cgcaggaaat aatgttttca
    23221 tctgcaatga atgcgtagct ttatcacaag aaattataaa agaagaattg gctgaagaag
    23281 tccttgccga tttgacagaa gttccaaaac caaaagagct tcttgatgtt ttaaatcaat
    23341 atgtggttgg tcaagatcgt gctaaacgtg ctttatcagt tgctgtgtac aatcattata
    23401 agcgtgtctc gtttacagaa agtcgtgatg acgatgatgt ggatttacaa aagtccaaca
    23461 ttttgatgat tggaccaaca ggttcaggaa aaaccttctt agcacaaact ctggctaaaa
    23521 gcctcaatgt accatttgct attgcagatg caacttcttt gactgaagca gggtatgttg
    23581 gagaagatgt ggaaaatatt ttactcaaac tgattcaggc tgctgactat aatgtcgaac
    23641 gagcagagcg tggtattatt tatgttgatg aaatagataa gattgctaaa aaaggtgaga
    23701 acgtatctat cacacgtgat gtatctggtg aaggtgtaca gcaagccctt cttaaaatta
    23761 ttgaaggtac ggtagcaagt gttcccccac aaggtgggcg gaagcatcct aatcaagaaa
    23821 tgatccaaat tgatacaaaa aatatcttgt ttattgttgg cggggctttt gatggcatcg
    23881 aggagattgt taaacaacgt ttaggtgaaa aagttattgg ttttggtcaa aacagccgta
    23941 aaattgatga caatgcttct tatatgcaag aaattatttc agaagatatt caaaagtttg
    24001 ggcttattcc agaatttatt ggccgcttac cagttgtggc agcccttgaa caactaaaca
    24061 catcagattt gattcaaatt ttgacagaac caagaaatgc cctggtcaag caatatcagg
    24121 cccttctttc ttacgatggc gtcgaattgg catttgataa ggaagcctta gaagccattg
    24181 ccaataaagc cattgaacgt aagacaggag cacgtggtct tcgttctatt attgaagaaa
    24241 cgatgttaga cattatgttt gaaattccaa gccaagaaga tgtcacaaaa gtgcgtatca
    24301 ccaaggctgc tgtcgaaggc aagtcaaaac ccgttttaga gacagcttaa ggagaaataa
    24361 tggctgaaga acaagtctta aatacccata acgcctcaat tttattgagt gctgccaata
    24421 aatctcatta cccccaagat gatttgccag aaattgccct cgctggacgt tcaaatgttg
    24481 gtaaatcaag ttttattaat accatattgg ggcgcaaaaa tttggcaaga acctcaagca
    24541 agccaggaaa aacccaacta ttaaattttt tcgatattga tgacaagctt agatttgtgg
    24601 atgtccctgg ttatggctat gccaaggttt ctaaaagtga acgggccaaa tggggaaaga
    24661 tgatcgaaga atacttaacc accagagata atctgcgtgc tgtcgtgagt ttggttgatt
    24721 tacgtcatgc cccttcaaaa gaagatattc agatgtatga ctttttgaag tactatgaca
    24781 ttcctgttat tgttgtggca accaaagcag ataagatccc tcgtggcaaa tggaacaaac
    24841 atgagtctgt ggtcaagaaa gctttgaatt ttgacaaatc tgatactttt atagtatttt
    24901 cttcggtaga acgtattggt atcgatgatt cttgggatgc tattttagag caggtctagc
    24961 gataggtgtt gatttatcta tgctaaaaca ttctcagtag agggtgtttt tcttatcgaa
    25021 aacataaaaa atcatagtta ggtttaccga ttttacttga cgccttaatg atgacatgct
    25081 agtattttat attaaggaga tgagtcatga cacaagtagc ccaagggcgc tctaaaggaa
    25141 agtcattgtt atgccatcaa tgcaatgccc tttttgtatt tattattttt cttatcttgc
    25201 ttgctgtact ttttggtgtt cgatatcgta atagctctat tgaaggtatc tggcgaacaa
    25261 caagcattga tcagaagtta ggcgatgatt ttgctaaacg tcttactggt ttgcatcaga
    25321 gccctcttat tgatgatagt ttattaacgt catctcagat gatactaaca gttaaaaata
    25381 acaacgttga cttgagtttt agtgttcaag ttgaacgaga catttttgtc aaacgtttag
    25441 ctgcttatca ccaaaatgaa ttattaaaga cattaaagga aaatcattta gttgttggtg
    25501 acttgagtag taaagaacgc caaattattg agaatagtat gccagctagc catgaattag
    25561 aaatgatttt agatcaagct tttgagaaat tagcttctca gatcggaggc aaatataatc
    25621 aaaaaacagg acatttatct gctgttgttc tcaaaggaaa agttaatcgt attttgcaca
    25681 ccattgatat caaagaagaa gtagcagcgg gacatacttc tttttcaaaa ggattgctca
    25741 cacctaatgg ttattttgat tacaccagat ttggaaagaa acttgagtta ttaggcgatg
    25801 aaaaaattat ttttaaaaaa gcgctaaaaa aaagtccgtc aagtgtataa cgtagtcaca
    25861 agacggattt tttcatgttt tgaaaattat tcaattgaag aagtttatta ctgatctttt
    25921 tgcctaatca ctagttgtcc ttcttttagg attgcctgaa gttttttgac ttctggatgg
    25981 tcaagataat aatcagttat acggtcacga atttcctgtt cgataatacg tcgtaatgga
    26041 cgagctccca tagcgtgatt gtaccctaaa tctatcaaat gagctttagc gtcatcagca
    26101 atcgttaaac taataccttt ttttgcggtg gtttgattta cttcagctag cattaaatca
    26161 acaatttctt ctaaattttc tttttgcaga tgattaaatt taatgatact attaaaacgg
    26221 ttcaaaaact ctggtctgaa ataaggtgca atgcgatcca taatgttaga ctcagaagtt
    26281 tccgtatctt gttggccaaa accggcattt gatgtagcaa taataacggt atttttaaag
    26341 ttaatagtat ttccttgtcc atctgtcaat cgtccatcat ctaacacttg tagaagaagt
    26401 gtaatgattt gaggatcagc tttttcaatt tcatctagta agacaatagc ataagggtta
    26461 cgacgaacac gctcagttag ggtattatta ttatcatcgt agccaacata accagccgtt
    26521 gtcccaatca attttgacac agcagtgcga tcgttatatt cggacatatc aagtcgaata
    26581 atagcatctt tggaaccaaa taaatcaagt gctaattgtt tagctaactc tgttttacca
    26641 acaccagttg gacccacaaa aaggaaagaa cctattggac gtttaccatc atcaaaacct
    26701 gcccgatttc gtcgaatagc acgtgctact gctgcgacag cctcatcttg tccgatgaca
    26761 tggcttttta agcggctgct aattcctttg agcctttcta aatcattagt ccccatgtta
    26821 gagacaggaa taccagttaa gcgctctaca gactctgcga tatcattgac tgtagcagtg
    26881 acattttggc tttggttatg ttgctcaatt tgcttttgta atgtttcaat ccgtgttttt
    26941 gctgctaaag ctttttcaaa gtcttctttg gcgacagctt tttcttgact ctctttttgt
    27001 ttagctattt cagtttcgag tgtttttaag tcagtgaccg ggtgttgcgc agctaaatga
    27061 gcagctgtca tatccagtaa gtcaattgct ttatctggca ggctacgctg tgggatgtat
    27121 tgaatagaat aatcaacagc agcttttaga acattatcag gaagggtaat atggtggtgt
    27181 tgttcataaa gattacgaat acccattaaa atgtgaaaag tatcttcagc tgatggtgca
    27241 ttcactttaa cttcattaaa gcgacgagca agagcagcat tttttaaaat agtattgcgg
    27301 tattcgtctt gagtagtagc accaatcagt gttaattctc ctcgtgacaa ggctggttta
    27361 agaatatctg caagtccctt tgagcctgaa tcactgcttg tggcaccagc accaactatt
    27421 tgatgaattt catcaaaaaa taagatgata ttcccagctt cttttacttc ttgaatcaag
    27481 ttttgaatgg tctcttcaaa ggaaccacga tactgtgtac cagcttcaag actagaaata
    27541 tcaattgata cgatttcctt gtttttaata gcagctggga catctccatt aacaatggct
    27601 tgagctaaac cttcaatgac tgcagtttta ccgacaccag catctccgac aaggacagga
    27661 ttatttttag ttcgtcgtgc caagatttca gcggtatctt gaatttcttt gttacgacca
    27721 atgacggggt caaggtgccc ttgacgagct tcttgtgtta agttagttcc gagttgagtc
    27781 aatacactat cagctttagg tgttaacatt tgagaatttg ttgctttggt tgtcgctaca
    27841 gggagttgtc ctgtttgacg atagtgttgg aattcttcgg gagttatttc gcgaccgtta
    27901 acgagatagc ggggattttc gctacgataa ccacccatgt ttgccattaa ttgattgaaa
    27961 atatcatcca tatttacaaa aggatcttta ccagaaaaat gtgtcatatc agttacctcg
    28021 caataaaaaa tagactataa gatgtttgta agcagtcgca gaatcgttgt taggatttca
    28081 catgatagga aaccctttgc taataaaatg attcagacat tatttttact catcttatag
    28141 tattattata atcaaaaggt cagtaaaggt caaacaaaaa cacttgattt tcaaaaagct
    28201 aaataaacac gaaaagtaag tgcttatatg atgactttag aataaatcat aagttttaaa
    28261 aagatcatcc tattctatag cacttaggct gtcaatgaga gaaaaacaac acgccaaacg
    28321 catgaagaaa cttttgtttt cagaaaacta gattcataat gacaaaatca atcaaagtag
    28381 tacactatag atgaggtgac tacgatgatt gattttatta tttctattga tgattgcgca
    28441 gttgaattgg atagtcgtca atcttggaaa attcgctacc ccttatcaac cattctattt
    28501 cttgtcttcg tttgtcagtt agctgacatt gaaacctgga aggagatgga agattttatt
    28561 gaaatgaatg aaccattgtt tgcgacctac gttgatttga gtgaaggttg tccgtctcat
    28621 gataccttag agcgtgtgat tagtcttgtt aattcagacc gtttaaaaga gcttaaagtt
    28681 caatttgagc aatcattgac aagcttagat gccgttcatc aactgatttc agtggacggt
    28741 aaaacgattc gaggcaatcg aggtaaaaat cagaagcctg ttcatattgt aacggcttat
    28801 gatgggggtc atcatcttag tttgggacag gtagcggttg aggagaaaag taatgaaatt
    28861 gttgccattc ctcagttatt gcggacaatt gatatccgta aaagcattgt aacgatagac
    28921 gcaatgggca cgcagacggc tatcgttgat acgattatta aaggtaaagc agactattgc
    28981 ttagccgtca aaggaaatca agaaacactt tatgatgata ttgctcttta ttttagtgat
    29041 gtcaacttat tggaagaact tcaagaaaat gcgcagtatt atcagactgt tgaaaaatct
    29101 aggggacaga ttgaagttag agaatactgg gtgtcttccg atatcaaatg gttgtgtcaa
    29161 aaccatccca aatggcataa gttacgtggt attgggatga ctcgtaacac gattgataag
    29221 gatggtcagc tgagtcaaga gaatcgttat tttatcttta gctttaagtc ggatgtcctc
    29281 acatttgcca attgtgtacg aggtcattgg cagatagaga gtatgcactg gttattggac
    29341 gttgtttatc atgaagatca tcatcagaca ttggataaaa gagccgcatt taacctaaat
    29401 cttatccgaa aaatgtgctt atattttctc aaagtgatgg tatttcctaa aaaagacctc
    29461 agttatcgtc gcaaacaacg gtatatttct gtccatttgg aagattattt agtccaatta
    29521 tttggagaaa gaggctaagc agatgattga tttaaaaagg aatcttttca aaattgatgt
    29581 ccgggcacaa aaggatgaag agaaagtttt catgcgtacg gcgtgagaaa aacaaatgtt
    29641 ttcattaaca agttggcgct ttcatggtat aataaagtgc taagacgcaa ttctattata
    29701 agggggaatc atggaagcac tcaaaaaaat tgccggtgtt accgctgcgc aatatgtgac
    29761 tgatggcatg accattgggc ttggaactgg gtcaacggct tactattttg ttgaggaaat
    29821 tggccgtcgc gtaaagcaag aaggactgca agtggttggt gtgaccacgt caagtgtgac
    29881 tagcaagcaa gcagaaggct taggcattcc tttaaaatcg atagatgata ttgatagcat
    29941 tgacctcacc gtagatggtg ctgatgaagt ggataaggat ttcaatggaa tcaagggtgg
    30001 cggcgcagcc ttactaatgg aaaaaattgt tgcaacacca acaaaagaat acatctgggt
    30061 tgttgatgct tctaaaatgg tagagcatct gggtgccttt aagttaccag tcgaagtcgt
    30121 tcaatatggt gctgatcgtt tgttccgtgt ctttgaaaaa gctggttaca aaccgtcttt
    30181 tcgtatgaaa ggtgatagtc gtttggtgac agacatgcaa aactatatta ttgatcttga
    30241 tttgggttgt attaaagatc ctgttgcttt tggtcacctg ctagatggaa cagttggtgt
    30301 tgtggaacac ggtctcttta atggtatggt tgataaggtg attgttgcta gtaaagacgg
    30361 cgttactgtt ttagaagcgc ctaaagcagg ctagtcttag catataacag tgttaatata
    30421 ttttataggt attggggagt caaccgtaac ctcccctaga ttggagactt atgtcaaaat
    30481 ttaatcgtat tcacttggtt gttttagact ctgtcggtat tggtgcagcg ccagatgctg
    30541 acaaattctt taatgctggt gtagctgata cagattctga caccctcggt catatttcag
    30601 aaacagcagg cttatcggtt ccaaatatgg caaaaattgg acttggaaac atttctcgtc
    30661 cgataccact aaaaactatt ccaacagaag acaatcctac tggttacgtg accaaattgg
    30721 aagaagtatc tcttggaaaa gataccatga caggccattg ggaaattatg ggcttgaaca
    30781 ttacggaacc ttttgacact ttctggaatg gtttcccaga agagatttta actaagattg
    30841 aagaattctc aggtcgcaaa attattcgtg aagctaataa accctattca ggaactgcgg
    30901 ttattgatga ttttggtccg cgtcaaatgg aaacaggtga gttgattgtt tacacctcag
    30961 cagacccagt gcttcaaatt gcagcccatg aagacattat tcctgtggaa gagctttaca
    31021 agatttgtga atatgctcgc tccatcacgc ttgaacgccc tgccctttta ggccgtatta
    31081 ttgcgcgtcc ttatgtaggc gaaccaggaa actttacacg tacggctaac cgtcatgact
    31141 atgcagtgtc tcctttccaa gataccgttt tgaacaaact ggctgacgca ggcgtcccaa
    31201 cttatgccgt tggtaagatt aatgacatct ttaatggttc aggtattaca aacgacatgg
    31261 gacacaataa gtcgaacagc catggtattg acacgcttat taagactctt caattacctg
    31321 agtttactaa gggattctcc tttactaacc tcgttgattt tgatgccaac tttggtcatc
    31381 gtcgtgaccc agagggttat cgtgactgct tgcatgaatt tgacaatcgc ctacctgaaa
    31441 tcttcgcaaa tatgaaagaa gacgatttgc ttctcatcac tgctgaccat ggtaatgacc
    31501 caacctatgc aggcaccgac cacactcgtg aatacattcc attgcttgcc tactctgcat
    31561 cctttactgg aaatggtctt attccacaag ggcattttgc ggatatttca gcaactgttg
    31621 cagaaaattt tggagttgat acagccatga ttggggagtc attccttggt cacttaaaat
    31681 aagaaaatta gttgataatg gaagaaatca cgatttatca taatccaaac tgtggtactt
    31741 cacgtaatgt tcttgccatg attcgccatg caggtattga gcctactatt attgagtatt
    31801 tgcagacgcc acctaatcgg gagactttaa ttgagctctt acaatcgatg gcaatctctg
    31861 cgcaagaact cttgcgaacc aatgttcctg aatttgaggc tcatggatta gcaaatcaag
    31921 cagtagctga gaaagacgtt attaatgcca tgttgacgga tccaattttg atcaatcgtc
    31981 ctattgttgt gactcgcaaa ggagtaaaac tttgccgtcc ttctgagacc ttactggata
    32041 ttcttcctgt tcccctgcct agtccttata tgaaagagga tggcgagagt gtgaacccta
    32101 ttgaggtaaa aggagaaaaa gatgtcattg atgactaaaa ttaacgaaac aaaagacttt
    32161 ttagttacta aaggaattga aactcccgaa tttggattaa ttctgggttc aggccttggt
    32221 gaacttgctg aagaagtaga aaatgctatt gttattgatt atgcagatat tccaaactgg
    32281 ggtaaatcaa cagttgttgg ccatgctgga aaattagtct acggtgattt agctggtcgt
    32341 aaagtacttg ccctacaagg tcgtttccat ttttacgaag gaaacccgct tgaagtggtg
    32401 actttccctg ttcgtgtcat gaaagctctg ggatgtgaag gcgttcttgt cacaaatgca
    32461 gctggtggta tcggctacgg cccaggtacc ttgatggcaa tcacagacca tatcaatatg
    32521 accggaaata acccactaat cggtgaaaac ttggacgagt ttggtccacg cttccctgat
    32581 atgtctgatg cctatactaa ggtttatcgc aataaggcac atgaagtggc tgaaaaaatg
    32641 aacatcaaac tagaagatgg tgtttatatg ggcttaactg gtccaactta tgagacacca
    32701 gcagaaatcc gtgctttcaa agtattagga gcagatgctg tcggcatgtc aactgtgcca
    32761 gaagttattg tggctgctca ttctggactt aaagtacttg gcatttcagc catcactaac
    32821 tttgcagctg gtttccaatc agaattgaac cacgaagaag ttgttgaagt gactgaacat
    32881 attaaagaag atttcaaagg tcttgttaaa gctattttag ctgagttgta ggacgaacaa
    32941 aatcaactgg agcattatta caggaatgtt attttatgtc gtcagtttgg cacatctgtt
    33001 cgcaataaaa aaatcaaaaa ataatcacgg ggtgtgagtt ctatgaatgt tgaactcaga
    33061 ttctagcttt tctaactaac ataaccaacg aagggaaaga gacgtattcg gtttaaatta
    33121 agcatggact cgaacatttc ttcgtattaa tttttaaata ataaaggaaa gagagttagt
    33181 cctttcttat ttgaactcga tttttagctc tcttcttcta ttcaatatca attatgaaag
    33241 gaatggggtt gtattcaatt gaatacgggc ggaaagctcg gaaactagat aaactaactt
    33301 ttgtgctcac acatggcgtt agttccctaa atttcagttg ctttctgtcc gccctctgac
    33361 cttctacaaa ataaaaggaa aggtagggct aactgtattc attgaattga atacgggcgg
    33421 agaactgttt ttcttcctta taaaaaataa aaaaataaga aaggtgaggg ctgagttcat
    33481 taatttgaat tcgggctaag gacttggtca agaagataag ttgtctagaa aatcaggatt
    33541 ttctgccaac ttcctatttt gccatcgttc ttttaacgcc ctcagtatca taatttatgt
    33601 ctatccatat ttctgccaaa aaaggcgata ttgctgataa aattcttcta cctggagatc
    33661 ctttgcgcgc gaaatttatc gctgaaaatt tcctagaaga tgcagtgtgt tttaacgaag
    33721 tgcgtaacat gtttggctac acaggaactt acaaagggca ccgcgtttct gtcatgggaa
    33781 ctggtatggg gatgccttcg atctctatct atgctcgtga attaatcgtt gattacggtg
    33841 tcaaaacatt gatccgtgtt ggtactgcgg gtgcgattga cccagaagtt catgtgcgtg
    33901 aattggtgct tgcccaagca gcagcaacca actcaaacat tatccgtaat gacttcccag
    33961 aatttgattt cccacaaatt gctgattttg gtttacttga caaggcttac catatcgcca
    34021 gagaaatggg agtaacaact cacgttggga atgtgctttc ttctgatgtc ttttacacta
    34081 acatgcctga gcgtaatatg gctcttggta aattgggtgt taaagccatc gaaatggaag
    34141 cagcaggtct ttactattta gctgctcagc accatgtcaa agcccttgga atcatgacga
    34201 tctcagataa cttgaatgat ccaaccgaag atactacagc tgaagagcgc caaaccactt
    34261 tcactgatat gatgaaggtc ggcttggaaa ccttaattgc caatgactaa taatcaaaca
    34321 ctagacatcc ttttggatgt ctatgcttat aatcacgcct ttagaattgc taaagccttg
    34381 ccaaatatcc ctaaaactgc cctctattta ctagagatgt taaaagagcg cagagaattg
    34441 aaccttgcct ttctggcgga acatgcagca gagaatcgga ccattgaaga ccagtaccac
    34501 tgttcattat ggcttaacca atcgcttgaa gatgagcaga ttgccaatta cattttggat
    34561 ttagaagtta aagtaaaaaa cggtgctatt attgatttcg tcaggtcagt gtcgcctatt
    34621 ctttaccgac tttttctcag actaatcacg tcagaaattc caaacttcaa ggcttatatt
    34681 tttgatacaa agaatgacca atatgatacc tggcattttc aggccatgtt ggaatctgat
    34741 tacgagtttt tcaaggctta cctgtctcaa aagcagtctc gcaatgtgac gaccaaaagc
    34801 ttagcagaca tgttgacgtt gacctcctta cctcaggaaa tcaaggactt ggtttttttg
    34861 ttacgacatt ttgaaaaggc tgtccgtaat cctctggctc atttgattaa gccttttgat
    34921 gaagaggaac tgtatcgcac cactcatttt tcttctcagg cttttttgga aaacattatc
    34981 accttggcga ctttttctgg tgtaatctac cgatgtgagc ctttttactt tgatgatatg
    35041 aatgccatta ttaaaaagga gttgagcctt tggagacaat ctattgtctg atatttatca
    35101 aaaaacacga taacttgacc gatacaggtc ttactaccgt gtttttttta gtatgacgat
    35161 tgaaaaagac attaatcaaa ggttacttct tcgagaaggt attcgataaa acgttccccc
    35221 attttggaca agttggcttt ttcatgcttg ataaaaacaa tgtcaatttc gtcagggaca
    35281 tctagcggga tagccacaat ctggtcacca tttagattgc tatttagaat accactggca
    35341 acggtgtagc catctaaacc aatcattaag ttaaagaggg tggcacggtc actgaccaca
    35401 attgatttgt tgtggggcat ctgggacatc atctcttctg aaaaataaaa ggagttgtga
    35461 atcccttggt catagctcag gtaaggaaaa tctctcaagt cgtccatgct taataggctt
    35521 ttagttgcta gaggatttga tttgctgaca aaaatatgag gctgtgcctt aaataatgga
    35581 gaggcagtca aatgattgtc atcaaataat ttggtcaaga catctcggtt atagtcgttg
    35641 ataaagagaa caccaatttc agatcgaaag tttttgacat catcaatgat ttcccaagtt
    35701 cttgtctcgc gcaaaaagag ttcgtaccga gtcatgtcgg tccgcttgag gagtgagaca
    35761 aatgcattga ctacgaaggc ataatgttga gatgaaacgc taaagagctc tcggccagta
    35821 ttgtggtttt tatagcggtc ttctaacagt gatgtttgct ctataatttg gcgagcataa
    35881 gataaaaatt ccaccccatc ttttgtcaag gtgatccctt taggatttcg gttgaaaatg
    35941 gtaatgccca tctccatttc caaatccttg accgcattgg atagacttgg ttgtgtgata
    36001 aataattgct tagcagcttc attcatagag ccgcactcaa caattttgat aatataatgc
    36061 agttgttgaa ttctcataag tacagtctag ctcaaaaaaa ataaagacgc aagcacaaac
    36121 gtcatcatgg gtttagaact ttgaaaaagc gctggagtct tttctcaata tggcctagga
    36181 taaatatgat tcaattttga gagttgaatc tatcaatttc attgcccttt tatttttctt
    36241 gtgttatatt aatagtatta acaaataggt atttttctaa tcaaagggtg gtggtcgtgt
    36301 gaatgttact gaacaaaata gtcatcaaat cttaatccaa aaattattgg tcagtatcca
    36361 ctatttgact ctttttcgag atgaactgaa gcttgtagaa cgaactcctt ctatacttgg
    36421 aggggaattt ccagctcatt tagtacagtc tgagttggga gatattgttg cggccattga
    36481 taccttggat atgcagcaac gcttgattga gtctaccttt tggtatgaag aatcagcttt
    36541 taagttgatg aacaaaactt tggatattgt cgataattgg attaaaggag tggatcatct
    36601 gatagattta tgccagtcca aagaagtctt tcaaattatt attggagata aacgcattcg
    36661 agtttttggg gtcttaagtg atgttttttc atctttaaaa gtgagtgctt tgtcacttaa
    36721 ggaagctcct attccggatg tgctctatga acatatccag agggttaatc ttgaagaaga
    36781 agcttttata aaatattacc aaagccctaa ggtacccaca ggtgagtttg aataaatgat
    36841 tcggtaaaaa tgataaaatg agttgacgta agtatacaaa aaaagatata gtaggaaaga
    36901 tgtgttcaaa taacaaaaag ttttgacatc ttgttttaaa aaagctataa tagtttaaat
    36961 ttaggcacct ttaagtgagt ccagagaggc aaacaaggta tacaagataa aaaaagggaa
    37021 ttccctttta gtttgctgta gcctcgcttc tttggtagcg aggctttttg gtgcttaatg
    37081 agatattgac acattataga aaggataagt tatgaaagaa gaacgcccaa ttattgcttt
    37141 agacttttca tcatttgagg agactaaagc atttttagac ttatttccag cagaagaaaa
    37201 gctatacgtg aaaattggta tggaattata ttatgcgcaa ggaccagata ttgttcggta
    37261 tatcaaatcg ttagggcata atgtattttt ggatttaaaa ttgcatgata ttccaaatac
    37321 tgttcgtgct gctatggcag ttcttaaaga attagatatt gatatggcaa ctgttcatgc
    37381 agctggtggt gtagagatgc taaaagcagc tcgagaagga ctaggtcaag gctctacctt
    37441 aattgcggta acgcagctaa cttcaaccag tgaagaccaa atgcgtggtg atcaaaatat
    37501 tcaaacgagt cttttagagt ctgttttgca ttacagcaag ggggcagcta aagctcagct
    37561 agatggggtg gtttgttcgg cacaagaagt agaagctatc aaggcggtga cgcctacagg
    37621 atttaattgc ttaactcctg gcattcgtcc taaaggcagt aatattggcg atcaaaaacg
    37681 agtgatgact ccaaaccaag caagacgcat tggaagtgat tatattgtgg tagggcgacc
    37741 aattacccag gcaaaagacc cagtggctgc ttaccaagct ataaaagctg agtgggcagg
    37801 ctaacagata agattaggaa accaacactt gtctgttaaa gaagaaaaag gagaataaga
    37861 aatgacacta gcaagccaaa ttgcaactca attacttgat attaaagctg tttatttaaa
    37921 gcctgaagat ccttttacgt gggcatctgg cattaaatca cctatttaca ctgataatcg
    37981 tgtcaccctt tcttatccta agactcgtga tttaattgag aatgggtttg tggaaactat
    38041 cagggctcat ttcccagaag ttgaggtcat cgctggtaca gctacagcag gtattcctca
    38101 tggtgccatt atagcagata aaatgactct tccttttgct tatattcgca gtaagccaaa
    38161 agatcatgga gcaggcaacc agattgaggg gcgtgtgctt aaaggccaaa aaatggttat
    38221 cattgaagat ttgatttcaa caggtggttc ggtactagat gcagccgcag cagccagtcg
    38281 tgagggagct gacgttctgg gagttgttgc gattttcact tatgagttac caaaagctag
    38341 tcagaatttt aaagaagctg gtatcaagtt gattacgctt tctaattata ctgagctaat
    38401 tgcagttgca aagttgcaag gctatattac taatgatggt ttacatttac ttaaaaaatt
    38461 taaagaagac caggtaaact ggcaacaata aggaactatc agccaggttt atttttaatg
    38521 aaaaaatctc tttaacccca attcaaaatg ttatgttttg attgttttgt ctacattcct
    38581 tacacatcac attctaattt ctaacctttt aatggtggtt ttcttttatt tgtgttttaa
    38641 taaaaaagaa tgttttagga ttcatatctt agaaaggaag agtagctatg acttatcaag
    38701 atgcgacggc tatggctatt gctgttcaga ctggtcagac cacaccacta gaattagtaa
    38761 cccaggctat ttataaggct aaaaagttga accctacctt aaatgctatt acctcagaac
    38821 gctttgaagc agccctagaa gaagccaaac aaagggattt ttcaggtctg ccttttgctg
    38881 gtgtgcctct ttttttaaaa gatttgggac aagaattaaa aggtcactca tcaacctcag
    38941 gttccagatt gtttaaagag taccaagcaa ctaaaacgga tttatttgtg aaaagattag
    39001 aagctttagg ctttattatt ttagggcgtt ccaacacgcc tgaatttggc tttaaaaata
    39061 ttagcgatag cagtttgcac ggaccagtga atttaccaaa ggataataca cgaaatgctg
    39121 gtggctcatc tgggggagct gctgctctag tgtcatcagg aattagtgcg ctagcaactg
    39181 ctagtgatgg tggtggttct attcggattc cagcctcgtt taacggctta attgggctca
    39241 aacctagccg cgggcgcatg cctgtcggac ctggttctta tcgaagctgg caaggagcct
    39301 cagttcattt tgccttgacc aaatccgtta gagatactag aaatctactc tactatttac
    39361 agatggaaca aatggaaagc cccttccccc tagccacctt aacaaaaaat agtatttatc
    39421 aatcgctaca acgtcccttg acaattgctt tttatcaacg gttaagtgac ggtagcccag
    39481 tatctttaga tactgcaaaa gctttaagac aagcagtaac ttggttaaga gaacaagggc
    39541 atcagctagt tgaattggaa gagtttcctg taaatatgac agaagtgatt cgtcattatt
    39601 atattatgaa tagtgtggaa acggctgcta tgtttgctga tattgaagac acttttggac
    39661 gtccgatgac caaagacgat atggaaacca tgacctgggc tatttaccaa tcaggtaaag
    39721 acatcccagc ttggcgttac tcacaggtcc ttcaaaaatg ggatacgtac agtgcaacca
    39781 tggctagttt tcatgagact tatgacctgt tgttgacgtt cacaaccaac acaccagctc
    39841 ctaagcacgg agaacttgtc ccagattcga aactcatggc taacttggct caagctgaaa
    39901 ttttcagcag tgaagagcaa ttcaatttgg tcgaaaccat gtttggtaag agtctggcta
    39961 ttaatcctta cacagctctg cctaatctaa ctggccagcc agctattagt ttacctactt
    40021 acgaaactaa ggaagggctc ccaatgggca ttcaactaat tgcagccaaa ggtagagagg
    40081 acctattatt aggaattgca gagcagtttg aggcagcagg attattgaag attcctcaat
    40141 aataatctta taaaacagtt taactattat agattaactt tttaaagaga ttgagcgctc
    40201 actgataaca caacttaatc aaaatgttat actattctta tcttaataaa ggagttacta
    40261 tgaagaaatc agttacttta ctgtctatcg gacttgccag ccttttattg gcagcatgtg
    40321 cgccacataa atctcaaaaa tcaagttggg agactatcaa agaaaaaggg gtgttaaaag
    40381 tagctacccc aggaacctat cagccaactt ctttttacaa cgataataat gagttagtag
    40441 gttacgaagt agatatggtc aaggaaatcg gtaaacgact taacattaaa gtcaagtttg
    40501 ttgaaacagg atttgaccaa gcctttacct cagttgatag tggtcgagtg gatatttctt
    40561 tgaacaactt tgacattacc ccaaaacgtc agaaaaaata caatatctct acgccttata
    40621 aatacggggt aggaggcatg attgtccgtg ctgatggcag ctcaaacatg gctaaaaaag
    40681 atcttagcga ctggaaagga aaaaaagcag ctggcgcttc tggaacagag tacatgaaag
    40741 tagcgcaaaa acagggagct gaactggtga cctacgataa tgttacagga gatgtttatc
    40801 taaacgatgt ggctaacggt cgaacagatt tcattccaaa tgattaccca gctcaaaaat
    40861 tatttgtgga ttacatgtta tctcaaaatc caaatctaaa tgtcaaaatg agcgatgttc
    40921 agtacaaccc aaccgaacaa ggaattgtta tgaacaaaaa agacgatagc ctcaagaaaa
    40981 aaatagatgc tgttattaaa gacatgataa aagatggtag cttgaagaaa atatctgaaa
    41041 cctactatgc tggtcaagat ttgacaaaac cttttggcaa agacaaaaaa attcccgtca
    41101 ttgatacgaa agacgttaac taatacttga tgttaaagga gtcctaacca catgattaat
    41161 atcccattaa tgaaag
//
