LOCUS       NZ_CRAW01000005        20876 bp    DNA     linear   CON 12-DEC-2024
DEFINITION  Streptococcus pneumoniae strain SMRU702, whole genome shotgun
            sequence.
ACCESSION   NZ_CRAW01000005
VERSION     NZ_CRAW01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Streptococcaceae; Streptococcus.
REFERENCE   1
  AUTHORS   Informatics,Pathogen.
  TITLE     Direct Submission
  JOURNAL   Submitted (09-MAR-2015) SC, Wellcome Trust Sanger Institute, CB10
            1SA, United Kingdom
COMMENT     ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_001193635.1-RS_2024_12_12
            Annotation Date                   :: 12/12/2024 01:34:22
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 2,202
            CDSs (total)                      :: 2,158
            Genes (coding)                    :: 1,981
            CDSs (with protein)               :: 1,981
            Genes (RNA)                       :: 44
            rRNAs                             :: 2, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 37
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 177
            CDSs (without protein)            :: 177
            Pseudo Genes (ambiguous residues) :: 0 of 177
            Pseudo Genes (frameshifted)       :: 66 of 177
            Pseudo Genes (incomplete)         :: 114 of 177
            Pseudo Genes (internal stop)      :: 46 of 177
            Pseudo Genes (multiple problems)  :: 43 of 177
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:02:04
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3088
            Orig. end                         :: 23964
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CRAW01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20876
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="1"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..20876
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20876
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10876](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10876)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            19..867
                     /locus_tag="AK725_RS03580"
                     /old_locus_tag="ERS020212_00696"
     CDS             19..867
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /locus_tag="AK725_RS03580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00696"
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="WP_050079332.1"
                     /transl_table=11
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITPY
                     NIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSFIK
                     KHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSVEQI
                     VELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYHADML
                     VYQNQVVYGKSFADVRIGQPILYINSLYRVGLAINQGSFAKAYNVGVGSSWTIEIKKIE
                     G"
     gene            882..1430
                     /locus_tag="AK725_RS03585"
                     /old_locus_tag="ERS020212_00697"
     CDS             882..1430
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /locus_tag="AK725_RS03585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00697"
                     /product="ECF-type riboflavin transporter substrate-binding
                     protein"
                     /protein_id="WP_000403170.1"
                     /transl_table=11
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQA
                     LLSIIFGPIIGLLVGLIGHAIKDSLVGYGLWWTWIIASGLFGLVVGLFRKYVRVINSVF
                     DWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAIAGT
                     LLLLAYAGTQTRAGSLKKD"
     gene            1437..1628
                     /locus_tag="AK725_RS12910"
                     /old_locus_tag="ERS020212_00698"
     CDS             1437..1628
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AK725_RS12910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ERS020212_00698"
                     /product="hypothetical protein"
                     /protein_id="WP_050212383.1"
                     /transl_table=11
                     /translation="MKIKEQTRKLAAGCSKQCFEIVDRTDEVSSKHGFEVVDETDEVSN
                     HTYGKVKLTWFEEIFEEY"
     gene            1628..2092
                     /locus_tag="AK725_RS03595"
                     /old_locus_tag="ERS020212_00699"
     CDS             1628..2092
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566071.1"
                     /locus_tag="AK725_RS03595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00699"
                     /product="hypothetical protein"
                     /protein_id="WP_078132853.1"
                     /transl_table=11
                     /translation="MIDKVVRNLLLTFFFCKMTKIINFLTTILVKKKKMCYNVSKLREK
                     RKGAMMWVLGFILFLIFFYSNDSKKIKKLEKKIKRLERKEKGNAEMSRLLQEMIGKEPI
                     ITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFDGE"
     gene            2102..2308
                     /locus_tag="AK725_RS03600"
                     /old_locus_tag="ERS020212_00700"
     CDS             2102..2308
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /locus_tag="AK725_RS03600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00700"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_001176227.1"
                     /transl_table=11
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSII
                     IALKISQIFNETVESVFRLEEDE"
     gene            2308..2505
                     /locus_tag="AK725_RS03605"
                     /old_locus_tag="ERS020212_00701"
     CDS             2308..2505
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /locus_tag="AK725_RS03605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00701"
                     /product="hypothetical protein"
                     /protein_id="WP_050265569.1"
                     /transl_table=11
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFAL
                     IPVTEWIEKKSKNLVSEKGE"
     gene            2508..3242
                     /locus_tag="AK725_RS03610"
                     /old_locus_tag="ERS020212_00702"
     CDS             2508..3242
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /locus_tag="AK725_RS03610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00702"
                     /product="DUF3169 family protein"
                     /protein_id="WP_000730279.1"
                     /transl_table=11
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMPW
                     ISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAFNI
                     TGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLEFFA
                     TPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQLLAFL
                     LVGAIHVYINVMQLPMVKRYFK"
     gene            3254..3895
                     /locus_tag="AK725_RS03615"
                     /old_locus_tag="ERS020212_00703"
     CDS             3254..3895
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /locus_tag="AK725_RS03615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00703"
                     /product="CPBP family intramembrane glutamic endopeptidase"
                     /protein_id="WP_050265568.1"
                     /sec_met_domain="Abi (E-value: 1.8e-21, bitscore: 69.6,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLLKNLGWFLLALLSFFFIYGFIQGLATASLALGASPYAVTLLY
                     VVLAGVYVYGIYKWYQKAPVYIEKSGFNRFIWLPALVWFLSLVVQFFLPDDPSVNQQIA
                     TDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLASSLLFALI
                     HFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            3913..4143
                     /locus_tag="AK725_RS03620"
                     /old_locus_tag="ERS020212_00704"
     CDS             3913..4143
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /locus_tag="AK725_RS03620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00704"
                     /product="hypothetical protein"
                     /protein_id="WP_000832180.1"
                     /transl_table=11
                     /translation="MKRVILLAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAGV
                     LRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            4185..4382
                     /locus_tag="AK725_RS12915"
                     /old_locus_tag="ERS020212_00705"
     CDS             4185..4382
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="AK725_RS12915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="ERS020212_00705"
                     /product="hypothetical protein"
                     /protein_id="WP_050967371.1"
                     /transl_table=11
                     /translation="MKIKEQTRKLTAGCSKHCFEVVDETDEVSSKHGFEVVDETDEVSN
                     HTYGKATMTWFEEIFEEYKN"
     gene            complement(4463..6286)
                     /gene="lepA"
                     /locus_tag="AK725_RS03630"
                     /old_locus_tag="ERS020212_00706"
     CDS             complement(4463..6286)
                     /EC_number="3.6.5.n1"
                     /GO_function="GO:0003924 - GTPase activity [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="lepA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190: GTP-binding protein LepA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /locus_tag="AK725_RS03630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00706"
                     /product="translation elongation factor 4"
                     /protein_id="WP_001047204.1"
                     /transl_table=11
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREM
                     QAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAAC
                     EGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVIGLD
                     ASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQVRVM
                     DGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQDTRVGD
                     TVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPETS
                     QALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMDVSNPSEF
                     PDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVNVIYQIPLA
                     EIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFIVHKDFAYER
                     GKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGGDVSRKRKLLE
                     KQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(6365..7093)
                     /locus_tag="AK725_RS03635"
                     /old_locus_tag="ERS020212_00707"
     CDS             complement(6365..7093)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0042578 - phosphoric ester hydrolase
                     activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /locus_tag="AK725_RS03635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00707"
                     /product="metallophosphoesterase family protein"
                     /protein_id="WP_000133339.1"
                     /transl_table=11
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSHR
                     VLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNGGDTTINSILGRPLDAP
                     VDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKVWLR
                     KPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLHGIVF
                     TDQGMTEHHFIENDGFVAED"
     gene            complement(7095..8762)
                     /gene="recN"
                     /locus_tag="AK725_RS03640"
                     /old_locus_tag="ERS020212_00708"
     CDS             complement(7095..8762)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /gene="recN"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /locus_tag="AK725_RS03640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00708"
                     /product="DNA repair protein RecN"
                     /protein_id="WP_000923595.1"
                     /transl_table=11
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNMM
                     LGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGRSI
                     SRVNGQMVNLSVLRTIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKETYQT
                     SFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLDLNQERDKLLNH
                     KNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYYVLEDI
                     SKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEYNLLTGN
                     NLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKAQFQVRFS
                     KGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKEGKTSIVFD
                     EVDTGVSGRVAQAIAQKIHKIGQHGQVLAISHLPQVIAIADYQFFIEKISNDHSTVSTV
                     RLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            complement(8769..9200)
                     /locus_tag="AK725_RS03645"
                     /old_locus_tag="ERS020212_00709"
     CDS             complement(8769..9200)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /locus_tag="AK725_RS03645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00709"
                     /product="arginine repressor"
                     /protein_id="WP_001034415.1"
                     /transl_table=11
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRDI
                     KELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVKAQ
                     LIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            complement(9193..10008)
                     /locus_tag="AK725_RS03650"
                     /old_locus_tag="ERS020212_00710"
     CDS             complement(9193..10008)
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0032259 - methylation [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /locus_tag="AK725_RS03650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00710"
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="WP_001041079.1"
                     /transl_table=11
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPGE
                     KIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQNS
                     AKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISLSLI
                     LPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEVGFSV
                     LGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            complement(10001..10876)
                     /locus_tag="AK725_RS03655"
                     /old_locus_tag="ERS020212_00711"
     CDS             complement(10001..10876)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /locus_tag="AK725_RS03655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00711"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_050203378.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.2e-57, bitscore:
                     188.4, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKQEKLALVESALEDFYEDQQFASSLRESVLYSIHAGGKRIRPF
                     LLLEVLEALQVTIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFGEA
                     MAILAGDALFLDSYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQHLS
                     LEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVLDVTA
                     SFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQLPFETESIV
                     SVVESLRING"
     gene            complement(10873..11085)
                     /locus_tag="AK725_RS03660"
                     /old_locus_tag="ERS020212_00712"
     CDS             complement(10873..11085)
                     /EC_number="3.1.11.6"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /locus_tag="AK725_RS03660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00712"
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="WP_000043230.1"
                     /transl_table=11
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKEL
                     QATLDKAEKTLVKVMQEDGTESDFE"
     gene            complement(11063..12403)
                     /gene="xseA"
                     /locus_tag="AK725_RS03665"
                     /old_locus_tag="ERS020212_00713"
     CDS             complement(11063..12403)
                     /EC_number="3.1.11.6"
                     /GO_component="GO:0009318 - exodeoxyribonuclease VII
                     complex [Evidence IEA]"
                     /GO_function="GO:0008855 - exodeoxyribonuclease VII
                     activity [Evidence IEA]"
                     /GO_process="GO:0006308 - DNA catabolic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="xseA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000165.1"
                     /locus_tag="AK725_RS03665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00713"
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="WP_000417464.1"
                     /transl_table=11
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYF
                     SLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDGVG
                     ALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGV
                     DILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIF
                     ESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEKRMVTA
                     VRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQLVQA
                     RTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLMLDTSRIV
                     ARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            complement(12531..13169)
                     /gene="udk"
                     /locus_tag="AK725_RS03670"
                     /old_locus_tag="ERS020212_00714"
     CDS             complement(12531..13169)
                     /EC_number="2.7.1.48"
                     /GO_function="GO:0004849 - uridine kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="udk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /locus_tag="AK725_RS03670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00714"
                     /product="uridine kinase"
                     /protein_id="WP_001181378.1"
                     /transl_table=11
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYKD
                     QSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQEP
                     QDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQYLG
                     VVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     misc_feature    13209..13223
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.39"
                     /tool="antismash"
     gene            complement(13277..13579)
                     /locus_tag="AK725_RS03675"
                     /old_locus_tag="ERS020212_00715"
     CDS             complement(13277..13579)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /locus_tag="AK725_RS03675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00715"
                     /product="bacteriocin immunity protein"
                     /protein_id="WP_000985089.1"
                     /transl_table=11
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQSV
                     MANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            complement(13820..14698)
                     /gene="truB"
                     /locus_tag="AK725_RS03685"
                     /old_locus_tag="ERS020212_00717"
     CDS             complement(13820..14698)
                     /EC_number="5.4.99.25"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0009982 - pseudouridine synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0001522 - pseudouridine synthesis [Evidence
                     IEA]"
                     /GO_process="GO:0009451 - RNA modification [Evidence IEA]"
                     /codon_start=1
                     /gene="truB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145474.1"
                     /locus_tag="AK725_RS03685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00717"
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="WP_001013256.1"
                     /transl_table=11
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGVL
                     PIAVGKATRMVEFMQDEGKIYEGEITLGYSTTTEDASGEVVAETPVLSPLDEKLVDEAI
                     ASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDGQLA
                     RFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAEKVEA
                     GQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLAILEKR
                     GNLYKPRKVFS"
     gene            complement(14708..15982)
                     /locus_tag="AK725_RS03690"
                     /old_locus_tag="ERS020212_00718"
     CDS             complement(14708..15982)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /locus_tag="AK725_RS03690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00718"
                     /product="DUF2130 domain-containing protein"
                     /protein_id="WP_001002637.1"
                     /transl_table=11
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQELA
                     LAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEVQL
                     LENQLATLRLEHENQLQKTLSDLEKERDQVKNQLLLQEKENELSLASVKQNYEAQLKAA
                     SEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGSKGDF
                     IFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLVTMLEA
                     DNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVREQNIDIT
                     HFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQLRLANNKL
                     EDVSVKKLTRKNPTMKAKFEALKGE"
     gene            complement(16078..17337)
                     /locus_tag="AK725_RS03695"
                     /old_locus_tag="ERS020212_00719"
                     /pseudo=""
     CDS             complement(16078..17337)
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019346 - transsulfuration [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018365067.1"
                     /locus_tag="AK725_RS03695"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00719"
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase family
                     protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MTCDFKFETLQLHAGQVVTPATKSCVVPIYQTTSFVFDDT"
     gene            complement(17485..18282)
                     /locus_tag="AK725_RS03700"
                     /old_locus_tag="ERS020212_00721"
     CDS             complement(17485..18282)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /locus_tag="AK725_RS03700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00721"
                     /product="formate/nitrite transporter family protein"
                     /protein_id="WP_000254797.1"
                     /transl_table=11
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTAA
                     GAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISWRK
                     TAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLEAIL
                     ANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVAADSI
                     ANFGVGNMLRHWGVTFIGNFIGGGLLMGLPYAFLNKNEDTYVD"
     gene            complement(18517..18756)
                     /gene="kphA"
                     /locus_tag="AK725_RS03705"
                     /old_locus_tag="ERS020212_00723"
     CDS             complement(18517..18756)
                     /codon_start=1
                     /gene="kphA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /locus_tag="AK725_RS03705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00723"
                     /product="RNA-binding protein KphA"
                     /protein_id="WP_000379621.1"
                     /transl_table=11
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDVG
                     RVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
     gene            complement(18776..19048)
                     /gene="rpsP"
                     /locus_tag="AK725_RS03710"
                     /old_locus_tag="ERS020212_00724"
     CDS             complement(18776..19048)
                     /GO_component="GO:0000314 - organellar small ribosomal
                     subunit [Evidence IEA]"
                     /GO_component="GO:0022627 - cytosolic small ribosomal
                     subunit [Evidence IEA]"
                     /GO_function="GO:0003735 - structural constituent of
                     ribosome [Evidence IEA]"
                     /GO_process="GO:0006412 - translation [Evidence IEA]"
                     /codon_start=1
                     /gene="rpsP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /locus_tag="AK725_RS03710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00724"
                     /product="30S ribosomal protein S16"
                     /protein_id="WP_000268761.1"
                     /transl_table=11
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLVA
                     ENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     misc_feature    complement(19108..19124)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 23.37"
                     /tool="antismash"
     gene            19218..19427
                     /locus_tag="AK725_RS03715"
     CDS             19218..19427
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /locus_tag="AK725_RS03715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_000953865.1"
                     /transl_table=11
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDLL
                     VDDSLAGDIILLWRIQFGTFTTET"
     misc_feature    complement(19491..19500)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.31"
                     /tool="antismash"
     gene            19906..20118
                     /locus_tag="AK725_RS03720"
                     /old_locus_tag="ERS020212_00725"
     CDS             19906..20118
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /locus_tag="AK725_RS03720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="ERS020212_00725"
                     /product="hypothetical protein"
                     /protein_id="WP_000011696.1"
                     /transl_table=11
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFIL
                     SSFQKPFTGEEVEDFQDDDEIPTII"
ORIGIN
        1 gatatacaag gagataaaat gaataataat ttactggtat tacaatcaga ctttggtctg
       61 gttgatggtg cggtatcggc tatgattgga gtggctttag aagagtctcc aaccttaaaa
      121 atccatcact tgacgcacga tatcacgcct tataatattt ttgaggggag ctatcgtctc
      181 tttcagacgg tggattactg gcctgaggga acgacgtttg tatcggttgt cgatccaggt
      241 gtcggttcga aacgtaagag tgtagttgcc aagactgcaa aaaatcaata cattgtcacg
      301 ccagataatg ggacgctttc ctttatcaag aaacacgttg gcattgtagc cattcgtgag
      361 atttctgagg tggccaatag gcgtcaaaac acagagcatt cttatacctt ccacggtcgt
      421 gatgtctatg cctatactgg tgctaaactg gccagtggtc acattacttt tgaggaagta
      481 gggccagagc tcagtgtgga acagattgta gagcttccag tcgtagcgac catcatagaa
      541 gatcatctgg tgaagggagc cattgatatt ctggatgtgc gtttcggttc gctttggacc
      601 tctatcacac gggaagaatt ttacaagctg gaaccagaat ttggtgatcg ttttgaagtg
      661 accatctatc atgctgatat gctggtctat caaaatcagg ttgtctatgg caaatcattt
      721 gcagatgtga gaattgggca acccatcctt tacatcaact ctctctatcg tgtaggtttg
      781 gctatcaacc aaggttcctt tgccaaggcc tataatgtag gtgtcggttc atcttggacc
      841 attgaaataa agaaaataga aggataaaat aggagaatag tatggaaatc aaatttacaa
      901 ttaaacaagt tgttgctgtc ggaattggcg ctgccctctt tgtcgtcatc gggatgatca
      961 acattccaac ccctgttcca aatacaagca tccagcttca gtatgcggta caagcgctac
     1021 tttctattat ttttggaccg attatcggtt tgcttgtcgg gttgattggt catgcaatca
     1081 aggactctct tgttggttat ggtctatggt ggacttggat tatcgctagc ggactctttg
     1141 gtttagttgt gggacttttt agaaagtacg ttcgcgtgat caatagtgtt tttgactgga
     1201 aagatattct tatttttaat ctcattcaac tacttgcaaa tgcccttgtt tggggtgtct
     1261 tggcaccact tggagatgtt gtgatttatc aagaagcggc agaaaaagta tttgcacaag
     1321 ggattgttgc gggaattgcc aatggtgtat ctgtagctat tgcaggaact cttctcttac
     1381 ttgcctatgc aggaacccaa actcgtgcag gaagtttgaa aaaggactaa tactcaatga
     1441 aaatcaaaga gcaaactagg aagttagccg caggttgctc aaaacagtgt tttgagattg
     1501 tggatagaac tgacgaagtc agctcaaaac atggttttga ggttgtagat gaaactgacg
     1561 aagtcagtaa ccatacctac ggcaaggtga agctgacgtg gtttgaagag attttcgaag
     1621 agtattaatg atagataaag tggtcaggaa cttactcctg acctttttct tttgcaaaat
     1681 gacaaaaatc ataaactttt tgacaactat acttgtcaaa aagaaaaaga tgtgttacaa
     1741 tgtaagcaag ttaagagaaa agaggaaagg agctatgatg tgggtactag ggtttatact
     1801 atttctgatt ttcttttatt ctaatgattc taaaaaaatc aagaaactag agaagaaaat
     1861 caaaagactt gagcgaaaag agaaaggaaa cgcagaaatg tcgagattat tacaagaaat
     1921 gattggaaag gaaccaatta taacgggagt gtatattggg ccagataact gggaagttgt
     1981 ggatgttgat gaggaatggg tcaaactacg tagtgttgat aatacgggaa aagaaaaatt
     2041 caagttgcaa cgtattgaag atatccaaac cgttgaattt gacggagagt aggtgtgtaa
     2101 cgtgcaacta aaaaatcgtc taaaagagct tcgagctcgc gatggtctca atcaaaccga
     2161 cctagccaaa ctggcagggg tttccagaca gaccattagc ctactagaac gggatgagta
     2221 caccccatcc attatcattg ccctgaaaat atctcaaatt ttcaacgaaa cagtcgaatc
     2281 ggtatttcgt ttggaggagg acgagtgatg aacaagtata aagtgattta ttatgtagtg
     2341 gtcatagctt tattagtcag cgtatttcta ctgattggga tggacctaag ctggtttaat
     2401 ccctatcaaa gcgaccaatt tgtttgggtc tactttgctc tcatcccagt aactgaatgg
     2461 attgaaaaga aatccaaaaa tctagtaagt gaaaaaggag aatgaatatg aaaaagaaac
     2521 gtagattgtt atttttgatg tctattgtct tgggggggtt cttgggcatg tttgtaggga
     2581 tgtttaaggc acgtgtcgaa tcccacgaaa ttattttaga tgtaaaagcc ttgatgccat
     2641 ggatatcagc tatttgttta ctgataggtt tcattagtat gtttttgact ttcaatttct
     2701 taaagaaaag cagaaaattt cattccttgt atcaagagga aatggatgac gatctgaatg
     2761 aaacctatta tgtgcaaatg tatcggaatc ttgagtttgg aaccattgct tttaatatta
     2821 caggtgtagc gattccattg gctattttta tttcattaag tgaggtgatt atattgcata
     2881 caaaccctca aacatttttc ctttctttct tactctttgt ggtattctta gtcgctcaaa
     2941 aatctctttt taaaaccatt gcgattgttc gtcagtttga tttggaattt ttcgctacac
     3001 caaaggatgt cttgaactat ataaattctt atgatgaagg ggagcgtcag gctaatttgg
     3061 aacagagttt tcgaatttta ttccaattac atcaatatgt cttaccagcc ttatatattt
     3121 ttcttattat catttctttc ttgacaggag agattcagtt actagctttc ttgcttgtag
     3181 gagccatcca tgtttatatc aatgtgatgc agttacctat ggtaaaacgt tatttcaaat
     3241 aaaggagtta tctatgaaac tacttaaaaa ccttggctgg tttcttctag cccttctatc
     3301 ctttttcttt atctatggct ttattcaggg gctcgcgact gcgtcgcttg ctttaggcgc
     3361 ttcaccctat gctgttactc tactctatgt ggtcttggct ggagtatatg tgtacggcat
     3421 ttacaaatgg tatcagaaag ctcctgttta tattgagaag agcggcttta accgatttat
     3481 ttggcttcct gccttggttt ggttcttatc tctggtcgtt caattcttct tgccagatga
     3541 tccttcagta aatcaacaaa tagcgacaga cttgaccttg tctcaaccac ttttctcatt
     3601 ctttgctgtg gttatttttg ctcctttgac ggaagagatt gtttttagag ggatgttagc
     3661 acgctatctc tttcctaagc aggacaatag taaacgaacc ctgatttttc ttctggcatc
     3721 tagtcttcta tttgccttga ttcattttcc aggtgatgtg caacaatttt ttgtctattt
     3781 tagccttggt tttagtttgg gtttggctta cattagcaga aaaggtctgg tctacagtat
     3841 ttctcttcac gctttgaata atttagtcgg ctttttgatg attctcatgc tataatagag
     3901 tcaggaggtc acatgaaacg agtaatttta ttagcagtga ttcaggcagt cgttctattt
     3961 ttcatcattg gagcgctagc ttatgccttc aaaggcgatt tcttctataa ctatctagca
     4021 gttgtctttg ctcctattgc aggtgtactg cgttttggga cggcttacat aacggaaatt
     4081 gtcttgcctc gaaaggcagc cgaaatcgct gaaaagcgta aagcaggcaa aaattcaaaa
     4141 taaaagagtc cggtgaagtt catcggattt ttgtattata ctcaatgaaa atcaaagagc
     4201 aaactaggaa gctaaccgca ggttgctcaa aacactgttt tgaggttgtg gatgaaactg
     4261 acgaagtcag ctcaaaacat ggttttgagg ttgtagatga aactgacgaa gtcagtaacc
     4321 atacatacgg taaggcgacg atgacgtggt ttgaagagat tttcgaagag tataaaaact
     4381 aaaaaagcag accatctaag cctgctttac tattgattct tatataaatt tcctgtgaac
     4441 aaggaaaggc atttctgata acttattctt catccatact caagacgctg aggaaggctt
     4501 cttgcggaac ttcaactgat ccgatggatt tcatgcgttt cttaccagct ttttgttttt
     4561 caaggagttt acgcttacga gaaacgtcac caccataaca tttagcaagt acgttcttac
     4621 gaagggcctt gatatcagta cgagcgacaa tcttgtgtcc aatagccgct tggattggaa
     4681 cttcaaattg ttggcgaggg atgattttct tgagtttatc aacgatgagt ttcccacgtt
     4741 cgtaggcaaa gtccttgtga acgataaagc tgagagcatc caccttatct ccattgagaa
     4801 ggatatccat tttcaccagc ttagatgggc gatattctga caattcgtag tcaaagcttg
     4861 cataaccacg tgttgaagac ttaagtttat caaagaagtc aaagacaatt tcagcaagag
     4921 gaatttgata gataacattg acacggttat catcaatata gtccatagtc acaaagtccc
     4981 cacgcttacg ctgagctagc tccattactg ctccgacgaa ctcctgtggt accatgattt
     5041 gcgccttgac ataaggctct tcaatggtcg caatcttagt tgggtctgga aactcagatg
     5101 ggttagacac atccatagac tcaccgtcgg tcaaattaac tttgtaaata acagacggag
     5161 ctgtcatgat gaggtcaata ttgaactcac gctctaaacg ttcctggata acatccatat
     5221 ggagaagtcc aagaaatcca caacgaaaac caaatccaag tgcctgagat gtttctggtt
     5281 caaactgaag actagcatca ttcagttgca atttttcaag cgcttcacgc aggtcattgt
     5341 acttgtttga ttcgattggg tagagacccg caaagaccat aggattcatc tgcttataac
     5401 catgtaatgg ttctgccgca ggattggttg ccaaggtaac ggtatcaccc acacgagtat
     5461 cctgaaccgt cttgatagac gccgcaatgt aaccaacatc accagtcgca aggaaatcac
     5521 gaccaaccgc ttttggtgta aaaataccga cttcggccac atcaaaggtc ttactattgc
     5581 tcatgagctg aatcttatca ccaggtttga ccactccgtc catgacacgc acttggagga
     5641 taaccccacg gtaagcatcg taaacagagt cgaaaatcaa ggccttaagt ggcgccgtca
     5701 catcacccgt tggtgctggt actttttcta caatttgctc gaggatttct tcaatcccaa
     5761 tcccagcctt ggcagaagcc aaaactgctt cactggcatc caaaccaatc acatcttcaa
     5821 tctctgtacg cacgcgctcc ggatctgcag ccggcaggtc aattttatta atgataggca
     5881 tgatttccaa atcattatcc aaagccagat aaacgttggc aagagtttga gcctcaattc
     5941 cttgagccgc atcgaccacc aaaatagcac cctcacaggc agctagcgaa cgtgaaactt
     6001 cataggtaaa gtcaacgtgc cctggtgtgt caatcaagtg gaaaatataa gtttctccat
     6061 cttttgcagt gtaattcaac tcgatggcat tcaacttaat agtaattcca cgttctcgct
     6121 ctagatccat gctatccaaa agctgggcct gcatttcacg acttgaaacc gtctctgttt
     6181 tttccaaaat gcggtctgct agagttgatt ttccgtggtc aatatgggcg ataatagaga
     6241 agttacggat cttctcctgt cgttttttca attcttctaa gttcatgatt ctcttccttt
     6301 cagggtatct atttattata aattgttttt gatattttga caagaccata ccctgctagg
     6361 agtactaatc ttcagcgaca aagccgtcat tttcgataaa gtggtgttct gtcattcctt
     6421 ggtctgtaaa gacaatcccg tgaaggacac caccataaac agctcctcca tccattccaa
     6481 tcttgccatc ttctgtagtc caaagctcag atgtaccgcg ttcttgctgt aacaaaccat
     6541 agaccggtgt atgaccgaag acaatggttt ttccagtatg attttcagct ccgtggaatg
     6601 gttttctaag ccatactttt ttataatctg ttgtttcatg ccagtcatcc aaggtcaaat
     6661 caatacctgc gtgaacaaag atatacttgt ctgtctctac tacaaatggc atttgacgaa
     6721 tgaattcgac caagtctgcc gcttcagcgg caacccgctt ggcatcttct actccatcaa
     6781 ctggtgcatc caagggacga cctaggatag agttaatggt tgtatctcca ccattgcgac
     6841 gataatggtc ataactttct tctgggtcat ctagccaagt caaaaacata tactcgtggt
     6901 ttccagacaa acagatagcc ccttgattgt ccaccaagtc cttgaccatt tcaagaacac
     6961 ggtgactatc ctcacctctg tcaatcaaat cacctagaaa gagcaactgg gtctgaccat
     7021 cccaggtttt aagaaggtct tccagcatcc cagcttttcc gtgaacatct ccaattacat
     7081 aataatctgt catcttattt ctccctgttt ctcaacaatt ctctggcttg cgtcagggct
     7141 gcttctgtca catcatcacc tgccaacatc ttggcaactt cctccactcg ctcttcgacc
     7201 gtcaagagac gaacagtcga aaccgttgaa tggtcattac taatcttctc aataaagaat
     7261 tgataatctg caatcgcaat tacttgtggc aaatgggaga tagccaaaac ctgaccatgc
     7321 tgaccaattt tatgaatttt ctgagcaata gcttgagcaa cacgacctga aactcccgta
     7381 tccacttcat caaagacaat gctagtcttg ccttctttac gtgaaaaggc agacttaatg
     7441 gctaacatga gacgagataa ttcccctcca gaagcaacct taaccaaggg tttaaagtct
     7501 tctccagggt tggttgaaat ataaaactca accatttcat ttccctcacg actgaatttt
     7561 cccttactaa aacgaacctg aaactgggct ttttccatat aaagatcttg cagttcttgt
     7621 ttaatctcag cttcgagttg ctgagccaaa ttatgacgag cagaagcaag ttgacctgcc
     7681 aaattgacaa gattgacttc caacttctta agctctgctt ccatgtcctc agacgaaaga
     7741 ttattgcctg tcaagagatt gtattcttcc gtaatcttgg caaaataaag caaaacatca
     7801 tcaacagtcc caccatactt acgagtaata gtatgaagga ggtccaaacg attctcaacc
     7861 tgcatgaggc gattgccatc aaaatcaagg tcctcaatga tagcttccaa acgtttgcta
     7921 atgtcttcta aaacatagta ggtctcagac agagagcttg aaatttcacg gtattcaggg
     7981 tcatactctt cgacactttc catgtcattc atggctgaac gaacattggc cagacttgaa
     8041 aaatcttcat tgtccaacat actgtaggca ttggtcagtg tatccgcaat atttttgtgg
     8101 ttgaggagtt tatctcgctc ttgattgaga tccaagtctt ctccagcctg caagtttgct
     8161 gcctcaatct ctgccatttg aaattccaac atttcgatac gtgccttgtg ttcctgttgg
     8221 tttttcttga cttccagaac ctgcttgcgc attttccgat aggcatcaaa actcgtttga
     8281 taggtttctt tcaagtccca aaaagcggca tcaccaaatt catccaacat ctggatatgc
     8341 agttggggac gcattaactc ctcatggtca tgctgaccat gaatatctac aagatgttgc
     8401 ccaatagttc gcaaaacaga cagattaacc atctgaccat ttacacggct gatactacga
     8461 ccattttgca agatttcccg acggatgata atttcatcac ctaattctaa accttgctca
     8521 tcaaaaattt cctgtaaaag acgactattc tcaactgaga aaagcccctc aatctctgcc
     8581 tttggtgcac catgacgaat aacatctgtc gtcgcacgag ctcccaacat catattcatg
     8641 gcatcaatga taatcgactt ccctgcaccc gtttcaccag tcaggacagt catccccttt
     8701 tcaaaattga gggaaatagc ctcaataatg gcaaagtttt ttatcgaaat ttcaagtaac
     8761 atatagacct accaattttt tacttgttca aagatttcct ctgctagact tccacttctg
     8821 gcaatgacta aaatcgagct atcatcagtc aaacagctaa aaatcttgtc tgcaaaagtc
     8881 tcgattaact gagcttttac aaaagccgta tttcctggaa taacttggag attgatcatc
     8941 ttatccatca attcagccga ttcgatattg tcttcagcca gttgcagact ttttacgatt
     9001 gattttggca attcgtagac ataggtgttg tctctcaaag gaattttgac aatacctaac
     9061 tctttgatat ctcgggatac cgtcgcctga gtggcagtga tacctgcttc tttcaaatgt
     9121 tctacaattt cttcttgcgt gccgatttga taatctgtca ccaatcttct aattttttca
     9181 agtctctctt ttttattcat ttttaaattg actatgcgcc ctctctactg cttctttaat
     9241 ctcagcaaga atctgattgc ttgctgactt ttcttttttc aaatacgcta aaaattcaat
     9301 atttccatgt ccaccttgga tgggagaaaa gtccaagcca aggactgaaa aacctacctc
     9361 tactgccata gctgttacag attcaaggac attctgatga accttagcat ctcgaataat
     9421 tccatttttc ccaatctgct cacgtcctgc ctcaaactga ggtttgacaa gtgctaccac
     9481 ctgaccttga tcagccaaga cacggtgcaa ggctggcaaa atcagactaa gggaaatgaa
     9541 actcacatca atactggcaa agctcggctc ctgctcgaaa tcagtctttt cagcatagcg
     9601 gaaattgaac tgctccatgc tgacaactcg tgggtcttgg cgtaatttcc aagccaactg
     9661 attggtacca acatcgactg caaagaccaa cttggcacta ttctgtagca tgacatcggt
     9721 aaaacctcca gtagaggccc cgatatcaat cgtagtcgcg ccatccaccg acaaatcaaa
     9781 gacctgcaag gccttttcca gtttcaaacc accacggctg acatacttga gtttctcccc
     9841 cttgagtttt aattcggtgt catctggaat tttctctcct ggcttgtcaa accgttctcc
     9901 attaaggact gctacgacta ggccagccat cacacctcgc ttggcctgct ctctcgtttc
     9961 aaacaacccc tgtttataag ctagtacatc cactctttcc ttagccattg attctcaaac
    10021 tttctactac acttacaatc gattctgttt caaagggaag ctgctgggca atttcttcta
    10081 atttttcatt agcttgatcc agggtttggt tacaaaaggc aatggactct tccaagccca
    10141 acagggcagg ataggttgat ttttctgcct gcagatcctt ttgaggtgtc ttgccgattt
    10201 cctcaaaact agctgtcaca tccagtacat catctctgac ttgaaaagca agtccaatca
    10261 attcacccac agttttcagc ttcacctgca tttcaggtga caattcagct ataatagctg
    10321 ccgcttggaa gggataggct agtaacttcc cagtcttatt ggcatgaata gtctgaagtt
    10381 cttccaaaga caagtgctgg tgttcgccct ccatatccaa aacttgccct gctaccatac
    10441 ccagactacc tgaagcaagg gataagttgg caatcaagtc caccttgatc tgacttggca
    10501 aatctgcctg cgcaatcaag gcatatgagt ctaagaataa ggcatctcca gccaaaatgg
    10561 ccatagcttc accgaatttc ttgtgattgg ttaaccgccc tcttcgataa tcgtcatcat
    10621 ccatagcagg aaggtcatcg tgaatcaagc tccctgtatg aatcatctct aaggcagtag
    10681 ctacctgcgc gtgagcaggt ttgatggtaa cctgcaaggc ttccagaact tctaacaaga
    10741 gaaaaggccg aatacgcttg ccaccagcat gaatagaata gagaacagac tcccgtaaac
    10801 tagaggcaaa ctgctggtct tcataaaaat cttccaaagc cgactcgaca agagctaatt
    10861 tttcttgctt tttcattcaa aatcactttc tgttccgtct tcttgcatga ccttgaccaa
    10921 ggtcttttca gccttgtcca gcgtagcttg gagctctttt gacaagacca tgcccttttg
    10981 aaaggcagta atcgcatctt ccagagcaat ttcaccattt tccaaacttt ggacaatggt
    11041 ttccagttct gctagatttt cctcaaattt cttttgtttt gacatcttta acctctaatt
    11101 ctacttgacc atctcgcatc aaaagcgtta cttggtcttt tttcttcaaa ctctcaaccg
    11161 aatctacaac ggactcttct tttttgacaa tagcataacc acgcgccacg attcggctag
    11221 tatccaacat gagcaaagct tccgaaagtc gcttggcctc agcaaccttg gcgtcataaa
    11281 ctaacgccat ttggctacct aagagcttgt ccaactgtcc taaacggtct tgatagcgtt
    11341 ggattttggt aacaggtgat aattgtacta attgatgagt tcttgcttga actaattgtt
    11401 tgttatcaga aatccgagtt cgcaaacttt gtttcaaacg cagttgcagt tggtccaagc
    11461 gttgcaaata accgtcatac aagcgctcag gttgtctaaa gataacagac tgactgcatt
    11521 ttttcaaagc ctcttgtttc ttagatagaa catttcggac tgccgttacc atccgttttt
    11581 cctgattttg caaatgagct aatacatcca acttggtcac aggtgttgcc agttcagccg
    11641 ccgctgttgg cgttgcagcg cgtcgatctg ccacaaaatc tgccaaggtc acatccgtct
    11701 catgccccac actagagata actggcaaac gagattcaaa aatagctcgt accacaattt
    11761 cttcgttaaa ggcccagaga tcctcaatag aaccacctcc acgaccaata atgagcaaat
    11821 ccaaatcgtc ccgttgatta gcacgcgcaa tatttctagc aatttcctcc gcagcccctt
    11881 caccttgaac cttggtcgga taaagaagga tgtcaacacc tgggaatcgc ctgctgacgg
    11941 tcgtgataat atctcgaata acggctccac tacggctggt tactacacca attctcttag
    12001 aaaattgggg cagagcttgc ttgaagcgtt cttgaaacag gccttcttct gtcaattttt
    12061 tcttaagttg ttcaaactga atcgcaagcg ccccaacccc atcaggctca gctttttcaa
    12121 tgatgatgga gtagctacca cttggttcat agacctgtac acgcccaatc acattgatct
    12181 tcattccttc ttccaggtca aaccctaatt tctgataaat cccagaccag atggtcgctt
    12241 gaataactgc atggtcatcc tttagggaga aatattggtg agtaggtcgt ttacgaaagt
    12301 tggaaacttg accagttaaa tagacccgtt ccaagtatgg gtctttatcg aatttcattt
    12361 tcagatactt ggtcaaagtt gttaccgata aatacttttc catctccacc tactattcat
    12421 ttacttgctc tttcatgggt attattatac caaaaatatg cctaaaaatc tccatttatg
    12481 taccattatg agggaaaaat agaaaaagga ggcaaggcct ccacatgtga ttatttgctg
    12541 tttcgagctt cttccaaaat ctttgcaatc ttggtcgtca acaggtcgat agccacggta
    12601 ttgctaaccc cttcaggaat gacgatatca gcataacgct tagttgactc gataaactgg
    12661 tggtacattg gtttgaccac acctaagtac tggttaataa cgctatcaag gctacggcca
    12721 cgctcctcca tatcacgctt gatacgacga ataatgcgca catcgtcatc cgtatccaca
    12781 aaaatcttga tatccatcaa atcgcgcaga cgcttgtcct ccaagaccaa aataccctca
    12841 acgataaaga catcttgagg ttcctgacga taggtcttgc tactccgtgt atgctctgta
    12901 tagtcgtagg tcgggatgtc caccggacgc cctgccaaca attccttaat ctgctcgatc
    12961 atcaagtctg tatcaaaggc aaaaggatgg tcatagttgg ttttgacacg ctcttcaaag
    13021 gtcaaatgag actgatcctt gtagtatgaa tcatgctcaa tcatggaaat cttttcatca
    13081 ggaaaatgcg ataaaatggc tcttgaaaca ctggttttac caccaccaga accacctgtc
    13141 actccaataa tgattggtct attttgcatg ctatcctccg ttattttatc cgtcgtctat
    13201 tctatcacat tttttacaaa atttatagtc tcatcagcaa aaaacaccag agtcttccct
    13261 ctgatgttcg acagttttaa cgaaagccct gtagggtttg agcaagcatc tgcaagaaag
    13321 ccagtctccc tctttcctgg ctaggagctt tggcaatcca taaaccaaaa tcaatgacag
    13381 acttaggtgc ctggtaatga tgcgtcatga ggtaaagtga caacccttga ctcaaattgg
    13441 ccatgaccga ttggtatttt tcatttctgt ctaaattttg tatagcaaga cgaaacaggt
    13501 gactcaactc actattttca tttatttctt tttgttgaag aagttgctcc accctttctc
    13561 gaaactcatt tcgcatcatg gaattatcac accaaatcct gggcctaagt tcccatcaga
    13621 acctgtaatg gactctaaat atttatctga aagaatttta aattgcttca tttcacacct
    13681 ctaaatttct atatagatta tttgagtacc tacaactcgc aacaattgga atattataat
    13741 tcccaaaacc attctactat tagtatgggg ttttatcaag caattgttat ctatcacccg
    13801 atttttattc ctaaacgatc tagctaaaaa ccttccttgg cttatagaga ttgccccgtt
    13861 tttctagaat ggctaacaat ttatcatctt caaaggcagc cagttctttg tccgtttggt
    13921 ctagctcaat aaaacgacca aagcgaactt ctgtagcctc ttctggagtt aggaaaactt
    13981 tgacaaggtc acctgtccca atctctaaag gatggagaaa atctaattgc ccagcctcta
    14041 ctttttcagc aatttcctcc aaggcaagag cgtcttctaa ttgtaagcca gcagcactag
    14101 tacgagtcaa atgggacata tgagccgcat aaccaagctt ttcacccaaa tcaactgaca
    14161 aagtacggat gtacgtccct ttactgcatt ttacacgaaa agtgaatcgg gcaagttggc
    14221 catcataaga aatcggactt gttcgctcaa attgataaat ggtcacctga cgttctggac
    14281 gctccacttc ctgaccagca cgcgcatact catagagctt gcgaccatta accttaactg
    14341 ccgaatacat agggggaatc tgagtaatag gcccagtcaa gctagcaatc gcttcatcaa
    14401 caagcttttc atccaaggga gacaaaacag gggtttctgc gaccacttcc ccactagcat
    14461 cctcagtcgt cgtggaatag cccagagtga tttccccctc atagatctta ccctcgtcct
    14521 gcataaactc gaccatgcgt gtcgccttgc caaccgcaat cggcaaaaca cccaccacat
    14581 ccggatccaa ggttccgcca tgaccaattt tcttggttcc caaaatctta cgcagtttaa
    14641 aaaccgcatc atgcgaggtc attcctgctt ctttttttaa gttgataata ccgttcattt
    14701 ttgctttcta ctcccccttc agtgcttcga acttcgcttt cattgttgga tttttccggg
    14761 tcaatttttt aacagagaca tcttccaatt tgttgttagc tagacggagt tggttttcag
    14821 atgtagtcag gaatttctta acctcttcca tgcgtttgat ggccttgtcg atttcatcaa
    14881 tagcttttcc aaagttagtc gaagctgaat tatagttctt agcaaaagct agcttaaagg
    14941 catccaaatc ttcctcaaaa tgcgtaatgt caatattttg ctcgcgaacc aaggccaact
    15001 cctgcttgta ttttagggaa tttagcgccg cattacgtaa gagaccaatc aattggataa
    15061 agaattgagg acgaacaaca tacatttttt catactcgtg actgacgtca acaatccctg
    15121 tgttaaagta gtcattatca gcctcaagca tggtcaccaa aacggcatac tcacagttct
    15181 tctcccgacg gtccttgtcc aattccttgt aaaaatctgc attcttgtgc ttcttctctg
    15241 ttccgtccgc ttcgtttttc atctcaaaca tgatagaaat gatttcaact ccattttcat
    15301 cacactcacg gaagataaag tcccctttag acccacgcga agagaccttg ttatccttct
    15361 caaagtaagc atttggaaag gcgaaactac gaaccttgtt aaactcactc tctgcatact
    15421 gttctaggct ttccccaatc gcttttgtag attgttgagc cttaaaattc ttataaaact
    15481 cgacttgttc actagctgct ttaagctggg cttcgtagtt ttgcttaaca gaagccaaag
    15541 ataattcatt ttccttttcc tgcaaaagta gttggttttt aacctggtcc cgttcttttt
    15601 ctaggtcaga aagggtcttt tgcagttgat tttcatgctc caaacgcaag gtcgccaact
    15661 ggttttccaa gagctgtact tccttgtcct tagccaataa ggcctgatgg cttgtctgtt
    15721 caacttcttt cttggccaat tctttttctg tatcaaagtt ttggatttga ctctgcaatt
    15781 gcgcaatttc ttgatccttc tgagccagtt tagtctgttg ctcattcata gccttttgct
    15841 cagccaaggc cagttcctgc ctcatcctat cgtgtagttc cttatcaaac tctgccgttc
    15901 tcacttggga caaaagttca gcatactggc tttcatttac tgtaaagact tccccacagt
    15961 tgggacattt gatttcgttc attacattcc tctttctaga cttctgtaac cattatatca
    16021 tgcctgaggg aaaatcaaaa acagtgagtc aaaacccact gtttatcttc ttttacttta
    16081 aattttttcc aaggccaagc gtaagtcttc aatcaaatct tctacatttt caagaccgat
    16141 agacaagtgg atttgatttg gtgtgacacc tgctgcttct aggtcttttt ctgacaattg
    16201 accgtgagtg attgttgctg gatggacaac aagcgattta gcatctgccg cgtttgcaag
    16261 gtcagaaaag atttctaaat tatcaatgac cttgcgtgct tcttcctcgt cacctttgac
    16321 gtggaaggta aagattgaac cgacaccttt tggcaagtat ttctcagcca aggcataata
    16381 aggactatct gcaagttttg gataatttac cttttctacc ttaggatggt tgacaagaaa
    16441 atcaacaatt gtctcagcat tttgtacatg gcgttccaca cgaagtgaaa gggtttcaag
    16501 tctttgtagc aagaggaaag cattgaatgg tgacaaggct gcacctgtat cacgaagcaa
    16561 ttgaactcga acagctataa taaaggctgc tgcacccaca tcacgagtat aactcaaatt
    16621 gtggcagctt ggaccctcgt caacaaattg agggaatttc cctgaagccg tccagtcaaa
    16681 acgaccacta tcgacaatta ttcctccaat agttgtacca tgcccaccga taaacttagt
    16741 cgcagagtga atggcaatgt caacgccatg agagaagacg ttaatcaaat aaggtgttgc
    16801 aaaagtattg tctgacacaa gtgggatttg atgtttatga gcaatctctg ccagtttttc
    16861 caggtctgga atattaatca aggggttacc caaggtttca atcaagacaa gcttggtatt
    16921 gtctttgata gctgcttcta cttcctccaa attatcaata tcgacaaagg ttgttgtgat
    16981 accataacga ggaaggggtt ctttcaaaag attgaaggtt ccaccgtaaa tagtcgaagc
    17041 agccactaca tggtcaccag catgggcaag cgccaaaatc gtataagtca ctgcagtcat
    17101 acctgatgct gttgctagcg cttcaacacc accttcaagg gcagctgttg taggattggt
    17161 gatacgagta taaatgttcc ctggtttcct caaggcaaac agatcagcac cttcctacgt
    17221 gtcatcaaaa acaaaagatg ttgtttgata aatcggcact acacaagact tagtagctgg
    17281 agtcacaact tgaccagcat gtagttgtag agtttcaaat ttaaaatcac aagtcataag
    17341 gtgacctcca tatcatttta ttaaggatat tgtagcacct tgagttatag tttacaaata
    17401 tcagttttct atattttgat ataagaaata gctattacct tattttgaaa atgaaaaaag
    17461 cacgactcaa tcgtgctcat tttcttaatc tacataagta tcttcgtttt tattgaggaa
    17521 ggcatatgga agacccatca agaggcctcc tccgataaag tttccgatga aagtcacacc
    17581 ccagtggcga agcatatttc caacaccgaa gttggcaatt gaatccgcag caacactgaa
    17641 tttcacaatc gcgaaagaag caaagttcgc cgcaatgtgc tcgtttgtta agaatacaaa
    17701 catgtaaata gctgacaaca caagccaaag tttggcacca ccatctttga ccaaaataaa
    17761 tgacagaatc gcaatattta cgaaaatatt tgccaaaatc gcctcaagca agaccaattc
    17821 atttgagcgg cctaacttca tctcaacaac acctgagatg aaactatcgt gtgtcagatt
    17881 cgcataggct gccgaatgag caaagcccca ccctgctatc aaggctccga taaggttgaa
    17941 caaggtacag tatagtaaaa tctcagctgt ttttctccaa gagatttttt ttaagaaact
    18001 accagcagtc aagaacatca tgtttgaagt gaccaactcg gcattcaaaa aaacaatgta
    18061 ggccaagccc caagcaaaaa cgaatggaaa gaggaagcgt ccactacctg gtgcaatttt
    18121 attaatcaag tcagccccaa ctgcacctgc agcagtactg aaggttaaaa atgcacctgc
    18181 gaacatcgaa cgaatcgcat acttaaattt gctttgacta taaagacttt ctttcttatt
    18241 gcaagcaaat tcaatctttg agataaattc tgaagaaacc ataataaact cctaaatctt
    18301 ttttcttgat aattatatca caaactttag gttttaggaa gcgttttcta tatttcataa
    18361 aagtttatag tagattgaaa ctagaatagt acacctctac ttctaaaaca ttgttagaaa
    18421 tcgatttgac tgtcctgatc gatttgtcct gttcttgttt cattttacta tatcttctat
    18481 tccacacaaa aaagcgaaac atccgtcccg cccttcttat ttttcgtcaa taacgattct
    18541 tacttttttg tattcagttg ggacagagta gacaatcgtt cttatcgcag aaatagtgcg
    18601 acccttacga ccgattacac gacccacatc gctttgatca agattcaaat gatattccaa
    18661 aaattctggt gtatcctcaa tcttgatagt taaggcatct ggttgtgaaa ttaagggttt
    18721 cacaatcgca ataatgagat tttcaatcgt atccatctgt caacctactt taaacttatt
    18781 ttgaaaattt agaatcgtgg aattttttca atacgccttc ttttgaaagg atgttacgta
    18841 ctgtgtctga aggttgagct ccattagcca accatgcaag aacgcggtct tctttcaaag
    18901 ttacttggtt ttcagcaaca agtgggttgt aagttccaac tgtttcgatg aaacgtccgt
    18961 cacgtggtga acgtgaatct gctacgttga tacggtagaa aggttttttc ttagaaccca
    19021 tacgagtcaa acggatttta actgccattt ttaaagtctc atttctttaa ttttttattt
    19081 cggtgaaata gctgagctat ttagcacatg ttctattata gcagatttct ggcatgtgtc
    19141 aagaaaaaaa cttgacagac tataaatttc ttaaagtatt tagaaatttg ttagaatagg
    19201 aaataaatgt ttgaaagatg ctatccgtga atactatttt agaaaaattt tataaagaac
    19261 accaagtcaa acccttcata tcgcctgaac gagagttgga tacttggctt ctaagtccca
    19321 agcccgttcc caagcgaaat atggacttat tagtagatga ttcactagca ggagatatca
    19381 ttttactatg gagaatccag tttggtactt ttaccactga aacatgattt taaaaactcc
    19441 cattcgaata tgattcaaaa ttcgcttaga atcaatgttt tcccactttt tcaaaaaata
    19501 aattttcatc taatttaaat aactttcaat taagtgtgaa ttttgcttaa aatcattaaa
    19561 aaacacccca tggtgtgaac catgaagtgt tgtaaatgct gtgttgtagc tagttcttag
    19621 cgtttagaga actggctagc tttacgagct ttcttaagat ctggtttcca aaatactttg
    19681 agtacactta tggtattgat gcccctaaac atctaaaaac tctggtagaa aaagggtatg
    19741 ctcttgtcga aacttctttt gactcacttg accatctaaa tactaccatg aaaaagaata
    19801 tcctgaagaa gaagggagtt actggacttt ctaaaatgaa atcttgcgac ctggatcaag
    19861 cccttcatga gcatttttca gaagaagaat tagctggtca ctttcatgtc cttctatgga
    19921 cttttttaca atggcattgc tatcacaccc aatacctatc taagcgcctg gttcgtaaac
    19981 tttattgcag ctcttcctct aaatttccta attgttgaac caattgcccg ttttatacta
    20041 agttcttttc agaaaccatt tactggggaa gaagttgaag attttcaaga tgatgatgaa
    20101 atcccaacta ttatctaagc cagttctgta aactactaat atttgaaatc cacttccttt
    20161 tagggtacaa tggttataaa tgaatttttg agaggatcag aatgaaaaaa ctagcaaccc
    20221 ttcttttact gtctactgta gccctagctg ggtgtagcag cgtccaacgc agtctgcgtg
    20281 gtgatgatta tgttgattcc agtcttgctg ctgaagaaag ttccaaagta gctgcccaat
    20341 ctgccaagga gttaaacgat gctttaacaa acgaaaacgc caatttccca caactatcta
    20401 aggaagttgc tgaagatgaa gccgaagtga ttctccacac aagccaaggt gatattcgca
    20461 ttaaactctt ccctaaactc gctcctctag cggttgaaaa tttcctcact cacgccaaag
    20521 aaggctacta taacggtatt accttccacc gtgtcatcga tggctttatg gtccaaactg
    20581 gagatccaaa aggggacggt acaggtggtc agtccatctg gcatgacaag gataagacta
    20641 aagacaaagg aactggtttc aagaacgaga ttactcctta tttgtataac atccgcggtg
    20701 ctcttgctat ggctaatact ggtcaaccaa acaccaatgg cagccagttc ttcatcaacc
    20761 aaaactctac agatacctct tctaaactcc ctacaagcaa gtatccacag aaaattatcg
    20821 aagcctacaa agaaggtgga aaccctagtc tagatggcaa acacccagtc tttggt
//
